CN104587251B - A kind of Chinese medicinal capsule and preparation method thereof for treating gout - Google Patents
A kind of Chinese medicinal capsule and preparation method thereof for treating gout Download PDFInfo
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Abstract
The invention belongs to field of traditional Chinese medicine technology, in particular to a kind of Chinese medicinal capsule and preparation method thereof for treating gout.The present invention is formulated by the Chinese medicine material of following parts by weight: 28-30 parts of Caulis Perillae, 20-23 parts of solid carbon dioxide leech, 20-25 parts of cassia seed, 28-30 parts of lopseed, 15-17 parts of corn stigma, 18-20 parts of Poria cocos, 5-7 parts of radix scutellariae, 7-11 parts of radish seed, prolongs and entangle 7-11 parts, 5-7 parts of Radix Notoginseng recklessly, 5-7 parts of asarum, 7-11 parts of radix aconiti agrestis, 20-25 parts of fructus lycii, 10-13 parts of silkworm excrement, 11-15 parts of Ramulus Cinnamomi, 2-4 parts of rhizoma arisaematis, 11-15 parts of Radix Angelicae Pubescentis, 8-12 parts of Dysosma versipellis, 8-12 parts of Chinese yam.The advantage of the invention is that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, drug is safe and reliable, it being capable of the warming channel and expelling cold, promoting flow of qi and blood circulation, kidney tonifying arresting seminal emission, so as to improve gout symptom, progression of the disease is controlled, enhances patient's immunity, and being capable of regulating the function of the stomach to resolve the turbidity, hemostasis stasis, detumescence ding-tong, mitigate patient's pain significantly, prevents complication.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, in particular to a kind of Chinese medicinal capsule and preparation method thereof for treating gout.
Background technique
Gout is the crystal correlation arthropathy caused by monosodium urate mineralization, with purine metabolic disturbance and uric acid excretion
Hyperuricemia caused by reducing is directly related, refers in particular to acute characteristic arthritis and chronic gout stone disease, and main includes anxious
The ictal arthritis of property, tophus formation, tophaceous chornic arthritis, urate nephropathy and uric acid lithangiuria, severe one
It may occur in which joint deformity and renal insufficiency.Currently, gout is present common disease, same people by the rare disease development of the past
Eating habit, lifestyle change are closely related.Gout is more common in middle-aged male, and women only accounts for 5%, mainly post menopausal female
Property, gout has rejuvenation trend.The natural history of gout can be divided into the fourth phase, i.e., the asymptomatic hyperuricemia phase, acute stage,
Intermittent phase, chronic phase.
Gout can be divided into primary and secondary two major classes according to cause of disease difference.Primary gout, which refers to, is excluding other diseases
On the basis of, due to caused by congenital purine metabolic disturbance and uric acid excretion disorder；Secondary gout refers to secondary to kidney trouble
Or the generation of uric acid caused by underexcretion caused by some drugs, myeloproliferative disease and chemotherapy of tumors increases.Gout is more
With multiple complications such as Central obesity, hyperlipidemia, hypertension, diabetes B and cardiovascular diseases, therefore not only to pay attention to acute
The active treatment of stage of attack will also pay attention to the treatment of paracmasis, and gouty arthritis breaking-out can be greatly reduced by carrying out well, delay
Disease progression prevents complication.
In the treatment, Western medicine drug mostly uses colchicin to relieve pain, and allopurinol inhibits uric acid to generate, and probenecid increases urine
Acid excretion.Western medicine generates a variety of side effects during taking, the gastrointestinal reactions such as including nausea,vomiting,diarrhea, reduces white thin
Born of the same parents, damage hepatic and renal function etc..In terms of traditional Chinese medical herbal treatment, medicament categories are few, mainly there is gout stator, heat-clearing arthritis cream, six
Refreshing ball etc. can alleviate the clinical symptoms such as slight illness, but effect is not apparent.
Summary of the invention
Insufficient according to prior art, the present invention provides a kind of pure Chinese medicine formula and its capsule that can effectively treat gout
Preparation method, the deficiency of a variety of side effects can be generated by compensating for Western medicine over the course for the treatment of, while also be provided for Chinese traditional treatment
A kind of good recipe quick, recurrence rate is low, achievees the purpose that treating both manifestation and root cause of disease.
A kind of Chinese medicinal capsule for treating gout disclosed in this invention, by the Chinese medicine material preparation of following parts by weight
At: 28-30 parts of Caulis Perillae, 20-23 parts of solid carbon dioxide leech, 20-25 parts of cassia seed, 28-30 parts of lopseed, 15-17 parts of corn stigma, Poria cocos
18-20 parts, 5-7 parts of radix scutellariae, 7-11 parts of radish seed, prolongs and entangle 7-11 parts recklessly, 5-7 parts of Radix Notoginseng, 5-7 parts of asarum, 7-11 parts of radix aconiti agrestis, Chinese holly
20-25 parts of matrimony vine, 10-13 parts of silkworm excrement, 11-15 parts of Ramulus Cinnamomi, 2-4 parts of rhizoma arisaematis, 11-15 parts of Radix Angelicae Pubescentis, 8-12 parts of Dysosma versipellis, mountain
8-12 parts of medicine.
A kind of Chinese medicinal capsule for treating gout, is preferably formulated by the Chinese medicine material of following parts by weight: Caulis Perillae 29
Part, 21 parts of solid carbon dioxide leech, 22 parts of cassia seed, 29 parts of lopseed, 16 parts of corn stigma, 19 parts of Poria cocos, 6 parts of radix scutellariae, 9 parts of radish seed, prolong
Entangle 9 parts recklessly, 6 parts of Radix Notoginseng, 6 parts of asarum, 9 parts of radix aconiti agrestis, 22 parts of fructus lycii, 11 parts of silkworm excrement, 13 parts of Ramulus Cinnamomi, 3 parts of rhizoma arisaematis, Radix Angelicae Pubescentis
13 parts, 10 parts of Dysosma versipellis, 10 parts of Chinese yam.
A kind of preparation method of Chinese medicinal capsule that treating gout, steps are as follows:
A, Caulis Perillae, solid carbon dioxide leech, cassia seed, lopseed, Poria cocos, radix scutellariae, radish seed and Dysosma versipellis mixing are taken, is added 7 times
The water of amount impregnates 1.5 hours, extracts 3 hours volatile oil, collects volatile oil, and medical fluid filters, and the dregs of a decoction are spare；
B, it takes the dregs of a decoction of surplus stock medicinal material and the step a to mix, adds 75% ethyl alcohol, impregnate 1 hour, extract twice,
1.5 hours every time, for the first time plus 7 times were measured, second plus 7 times of amounts, combined extract, filtering；It concentrates filtrate to opposite
1.30 when density is 80 DEG C, alcohol precipitation twice, adjusts concentration of alcohol to 75%, when to take supernatant to be concentrated into relative density be 80 DEG C
1.30, obtain medicinal extract；
C, above-mentioned medicinal extract is taken, volatile oil and vegetable oil that step a is obtained is added, the additive amount of vegetable oil accounts for medicinal extract and volatilization
The 3% of oily gross mass, mixing are ground 10 minutes with colloid mill, are stirred continuously, are cooled to room temperature, the Chinese medicine composition is filled
Enter in capsule housing to get the capsule.
Preferred embodiment is as follows:
The extraction of volatile oil is extracted using steam distillation or supercritical extraction in the step a.
It is extracted in the step b and uses membrane separation technique, ultrafiltration, alcohol precipitation, high speed centrifugation or macroporous resin method.
Instructions of taking: once in the morning and once at night, 2 tablets each time, warm water takes.10 days as a treatment course.
Pharmacology analysis:
Caulis Perillae: acrid flavour, it is warm-natured.Can regulating the flow of QI to ease the stomach, analgesic.It is bored to cure mainly chest diaphragm ruffian, gastral cavity pain, belch vomiting.
Solid carbon dioxide leech: taste is salty, bitter, mild-natured.Blood-breaking, by the stasis of blood.For abdominal mass lump in the abdomen, blood stasis, injury from falling down.
Cassia seed: sweet in flavor, bitter, salty, cold nature.Heat-clearing improving eyesight, relax bowel and defecation.For the puckery pain of hot eyes, the more tears of photophobia, headache
Dizziness, mesh is secretly unknown, constipation.
Lopseed: acrid flavour, hardship, it is warm-natured.Dispelling wind and eliminating dampness, removing toxic substances analgesic.For rheumatic arthritis, sore swollen toxin is controlled in external application.
Corn stigma: it is sweet in flavor, light, it is mild-natured.Return bladder, liver, gallbladder channel.Major function inducing diuresis to remove edema, calming the liver and benefiting the lungs.For it is anxious,
Chronic nephritis, oedema, acute hepatitis, chronic hepatitis, hypertension, diabetes, chronic nasosinusitis, lithangiuria, Biliary Calculi, urine is not
The diseases such as benefit, neonatal jaundice caused by dampness-heat.
Poria cocos: sweet in flavor, light, mild-natured, return heart, lung, spleen, kidney channel.Major function clearing damp and promoting diuresis, invigorating the spleen calming heart.For oedema
Oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.It is anti-aging with anti-oxidant, increase immune
Power improves the active effect of brain cell.Poria cocos has stronger diuresis, can treat ephritis, heart failure oedema.In addition there are also towns
Quiet effect, it is effective to neurasthenia.It is lightly seasoned mild-natured, it is apt to nourishing qi and blood, antitoxic heart-soothing and sedative, internal heat anticance；Medicinal peace, dampness removing without
Hurt healthy tendency, contained pachymic acid has the function of strengthen immunity, antitumor and calm, hypoglycemic etc.；The alimentary canal that can relax is flat
Sliding flesh, gastric acid secretion inhibiting prevent necrosis of liver cells, antibacterial and other effects.
Radix scutellariae: bitter, cold in nature, return lung, gallbladder, spleen, large intestine, small intestinl channel.There are heat-clearing and damp-drying drug, cool blood miscarriage prevention, detoxicating functions.Function
Warm heat disease, the infection of the upper respiratory tract, cough with lung heat, neonatal jaundice caused by dampness-heat, pneumonia, dysentery, hemoptysis, hot eyes, threatened abortion, high blood can be cured mainly
The diseases such as pressure, carbuncle swells furuncle sore.
Radish seed: acrid flavour, sweet, mild-natured, returns spleen, stomach, lung channel.Function help digestion and eliminate flatulence, lowering the adverse-rising QI to resolve phlegm.Dyspepsia stagnation is cured mainly,
Abdominal distention, belch hiccup, constipation, weight after rush down dysentery, phlegm choking, dyspnea and cough etc..
Prolong and entangles recklessly: acrid flavour, hardship, it is warm-natured.Its stem tuber containing a variety of alkaloids such as corydaline, Biflorine, be made pulvis or
Fluid-acet-extract etc., promoting blood circulation, sharp gas, analgesic.For chest side of body, epigastric pain, amenorrhea and algomenorrhea, postpartum stasis, tumbling and swelling.
Radix Notoginseng: sweet in flavor, slight bitter, it is warm-natured.Hemostasis stasis, detumescence ding-tong have the effect of dissipating stasis and stanching bleeding, detumescence ding-tong.It is main
Control hemoptysis, spit blood, bleeding from five sense organs or subcutaneous tissue, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, chest and abdomen shouting pain, fall servant swelling and pain.
Asarum: property is pungent, taste temperature, return lung, the heart, kidney channel.Function wind-dispelling, cold dispelling, row water are had one's ideas straightened out.Cure mainly air-cooled headache, rheumatism
Numbness pain, dentalgia, nasosinusitis, sip and cough.Modern pharmacological research shows that asarum analgesic activity is obvious.
Radix aconiti agrestis: acrid flavour, hardship, property heat.Dispelling wind and eliminating dampness, antalgic.It is used for treating arthralgia due to cold and dampness, arthralgia, trusted subordinate's crymodynia, trembles with fear
Hernia is had a pain, narcotic analgesic.
Fructus lycii: it is sweet in flavor, it is mild-natured, return liver, kidney, lung channel.Function tonifying kidney and benefiting sperm, nourishes the liver to improve visual acuity, moistening lung and producing body fluid.Treat liver kidney
The deficiency of Yin, essence and blood lose less, out of strength idle dynamic, amnesia insomnia, soreness of waist and knee joint, impotence and seminal emission, dizziness and tinnitus, blurring of vision, Heat Diabetes,
Blood deficiency chlorosis, cough due to consumptive disease etc..Modern pharmacological research report, fructus lycii, which has, improves and adjusts immune function, anti-oxidant, anti-ageing
Always, liver protection, promote body injury reparation, promote hematopoiesis function, protection endocrinal glands, protection retina, enhancing it is antifatigue and
The effect of hypoxia-bearing capability.It is usually used in treating senile dementia caused by liver and kidney deficiency disease, it is simultaneous to control cough due to consumptive disease, the vexed diseases such as quench one's thirst.
Silkworm excrement: it is sweet in flavor, pungent, it is warm-natured.Dispelling wind and eliminating dampness, regulating the function of the stomach to resolve the turbidity, blood circulation.The main rheumatic arthralgia of major function, limbs
It is unsuccessful, rubella itch, spasm of vomiting and diarrhoea, amenorrhoea, metrorrhagia and metrostaxis.
Ramulus Cinnamomi: it is acrid flavour, sweet, it is warm-natured.It is warming channel and expelling cold, the promoting flow of qi and blood circulation, analgesic.For being affected by the cold, stomach abdomen crymodynia, pain
Through pain in rheumatoid joints；Traumatic injury is controlled in external application, fracture.
Rhizoma arisaematis: it is bitter, pungent, it is warm-natured.Return lung, liver, the spleen channel.There is the function of expelling wind and relieving convulsion, reducing phlegm and resolving masses.Cure mainly middle wind phlegm
Heap soil or fertilizer over and around the roots, hemiplegia, paralysis of the limbs, anemophlegmatic vertigo, the insane spare time, infantile convulsion, tetanus, cough ant phlegm, carbuncle swells, scrofula, is fallen at facial paralysis
Scutching numbness, venomous snake bite.
Radix Angelicae Pubescentis: acrid flavour, hardship, slightly warm in nature.Return liver, kidney, bladder meridian.Major function expelling wind and eliminating dampness, eliminating cold to stop pain；Cure mainly chill
Arthritis with fixed pain caused by dampness；Lumbocrural pain, few the moon volt wind headache, dentalgia of having a headache.The modern pharmacology proves that Radix Angelicae Pubescentis have good analgesia, it is calm and
Anti-inflammatory effect.
Dysosma versipellis: it is sweet in flavor, bitter, it is cool in nature.It is clearing heat and detoxicating, activating microcirculation and removing stasis medicinal.Cure mainly venomous snake bite, traumatic injury；Worm is controlled in external application
Snake bite, ulcerative carbuncle furuncle, lymphnoditis, parotitis, breast cancer.
Chinese yam: it is sweet in flavor, it is mild-natured.Returns spleen, lung, kidney channel.Can tonifying spleen nourishing the stomach, engender liquid and benefic lung, kidney tonifying arresting seminal emission.It is eaten for spleen deficiency
Few, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, leukorrhagia, frequent micturition, and abnormal heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) good efficacy to suffering from a deficiency of the kidney.It is eaten for spleen deficiency
It is few, diarrhea loose stool, leukorrhea.
The advantage of the invention is that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, drug is safe and reliable,
Can the warming channel and expelling cold, promoting flow of qi and blood circulation, kidney tonifying arresting seminal emission control progression of the disease so as to improve gout symptom, enhance patient's immunity,
And can regulating the function of the stomach to resolve the turbidity, hemostasis stasis, detumescence ding-tong, significantly mitigation patient pain, prevent complication.
Curative effect judgement:
Effective: the symptoms were significantly improved for gout, arthralgia and ulcer skin lesion it is substantially reduced or disappear, control the state of an illness after supervention
Exhibition.
Effective: gout symptom is eased, and arthralgia mitigates, the remission of ulcer skin lesion.
Invalid: gout symptom is unchanged, and new illness occur in arthralgia and the increase of ulcer skin lesion area or other positions.
Treatment results: 172 patient with gout for the treatment of respectively take two sooner or later.10 days as a treatment course.Use 3 courses for the treatment of
After Chinese medicine of the invention, effective 161,93.61% is accounted for, effective 10,5.81% is accounted for, invalid 1, accounts for 0.58%, totally have
Efficiency is 99.42%.It can be seen that the present invention has preferable effect to the treatment of gout.
Several additional cases have been attached for further description:
Case 1:
In the summer, male, 50 years old, patient often went on business, and drank frequently.There is finger, toes painful swelling of joints, is with hypnalgia
Very, right finger anchylosis ulceration.Once allopurinol, rosickyite acid etc. were taken, the state of an illness is improved, but is stopped because having a stomachache discomfort
Clothes.It is to our hospital afterwards, it is diagnosed as gout, after taking 2 courses for the treatment of of capsule of the present invention, pain relief, the secretion at ulceration has
It is reduced, toes swelling and pain subtract clearly, continue after taking 2 course for the treatment of, and the above symptom of patient disappears, and blood uric acid has been approached normally, patient
A course for the treatment of is continued to strengthen, follow-up 1 year, is not recurred.
Case 2:
Poplar, male, 20 years old, peasant.Patient is after once drinking, burst left foot back, thumb swelling and pain, it is difficult to it falls asleep, office
The scorching hot redness in portion.After anti-inflammatory throe medicine is taken in locality, pain relief after a week.After, it is easily sent out after drinking or catching a cold
Make, on breaking-out, takes the medicines such as prednisone certainly.Breaking-out causes left foot part red and swollen heat pain afterwards, and function limitation comes our hospital and is diagnosed as pain
Wind, gives capsule of the present invention then, and after 2 courses for the treatment of, symptom disappears, and freely, no limping is discharged from hospitals upon recovery after 3 courses for the treatment of for walking.
Specific embodiment
The present invention is described in detail combined with specific embodiments below, but is implemented the invention is not limited to specific
Example.
Embodiment 1:
A kind of Chinese medicinal capsule for treating gout, is formulated by the Chinese medicine material of following parts by weight: 28 parts of Caulis Perillae, being done
23 parts of leech, 20 parts of cassia seed, 30 parts of lopseed, 15 parts of corn stigma, 20 parts of Poria cocos, 5 parts of radix scutellariae, 11 parts of radish seed, prolongs and entangle 7 recklessly
Part, 7 parts of Radix Notoginseng, 5 parts of asarum, 11 parts of radix aconiti agrestis, 20 parts of fructus lycii, 13 parts of silkworm excrement, 11 parts of Ramulus Cinnamomi, 4 parts of rhizoma arisaematis, Radix Angelicae Pubescentis 11
Part, 12 parts of Dysosma versipellis, 8 parts of Chinese yam.
Embodiment 2:
A kind of Chinese medicinal capsule for treating gout, is formulated by the Chinese medicine material of following parts by weight: 30 parts of Caulis Perillae, being done
20 parts of leech, 25 parts of cassia seed, 28 parts of lopseed, 17 parts of corn stigma, 18 parts of Poria cocos, 7 parts of radix scutellariae, 7 parts of radish seed, prolongs and entangle 11 recklessly
Part, 5 parts of Radix Notoginseng, 7 parts of asarum, 7 parts of radix aconiti agrestis, 25 parts of fructus lycii, 10 parts of silkworm excrement, 15 parts of Ramulus Cinnamomi, 2 parts of rhizoma arisaematis, 15 parts of Radix Angelicae Pubescentis,
8 parts of Dysosma versipellis, 12 parts of Chinese yam.
Embodiment 3:
A kind of Chinese medicinal capsule for treating gout, is formulated by the Chinese medicine material of following parts by weight: 29 parts of Caulis Perillae, being done
21 parts of leech, 22 parts of cassia seed, 29 parts of lopseed, 16 parts of corn stigma, 19 parts of Poria cocos, 6 parts of radix scutellariae, 9 parts of radish seed, prolongs and entangle 9 recklessly
Part, 6 parts of Radix Notoginseng, 6 parts of asarum, 9 parts of radix aconiti agrestis, 22 parts of fructus lycii, 11 parts of silkworm excrement, 13 parts of Ramulus Cinnamomi, 3 parts of rhizoma arisaematis, 13 parts of Radix Angelicae Pubescentis,
10 parts of Dysosma versipellis, 10 parts of Chinese yam.
Embodiment 4:
A kind of preparation method of Chinese medicinal capsule that treating gout, steps are as follows:
A, by deal described in embodiment 1, take Caulis Perillae, solid carbon dioxide leech, cassia seed, lopseed, Poria cocos, radix scutellariae, radish seed and
Dysosma versipellis mixing, the water that 5 times of amounts are added impregnate 2 hours, extract 2 hours volatile oil, collect volatile oil, medical fluid filtration, the dregs of a decoction
It is spare；
B, it takes the dregs of a decoction of surplus stock medicinal material and the step a to mix, adds 90% ethyl alcohol, impregnate 0.5 hour, extract two
Secondary, 2 hours every time, for the first time plus 5 times were measured, second plus 10 times of amounts, combined extract, filtering；Concentrate filtrate to phase
1.10 when being 80 DEG C to density, alcohol precipitation twice, adjusts concentration of alcohol to 90%, when to take supernatant to be concentrated into relative density be 80 DEG C
1.10, obtain medicinal extract；
C, above-mentioned medicinal extract is taken, volatile oil and vegetable oil that step a is obtained is added, the additive amount of vegetable oil accounts for medicinal extract and volatilization
The 5% of oily gross mass, mixing are ground 10 minutes with colloid mill, are stirred continuously, are cooled to room temperature, the Chinese medicine composition is filled
Enter in capsule housing to get the capsule.
The extraction of volatile oil uses extraction by steam distillation in the step a.
It is extracted in the step b and uses membrane separation technique.
Instructions of taking: once in the morning and once at night, 2 tablets each time, warm water takes.10 days as a treatment course.
Embodiment 5:
A kind of preparation method of Chinese medicinal capsule that treating gout, steps are as follows:
A, by deal described in embodiment 2, take Caulis Perillae, solid carbon dioxide leech, cassia seed, lopseed, Poria cocos, radix scutellariae, radish seed and
Dysosma versipellis mixing, the water that 10 times of amounts are added impregnate 1 hour, extract 5 hours volatile oil, collect volatile oil, medical fluid filtration, the dregs of a decoction
It is spare；
B, it takes the dregs of a decoction of surplus stock medicinal material and the step a to mix, adds 60% ethyl alcohol, impregnate 1.5 hours, extract two
Secondary, 1 hour every time, for the first time plus 10 times were measured, second plus 5 times of amounts, combined extract, filtering；Concentrate filtrate to phase
1.50 when being 80 DEG C to density, alcohol precipitation twice, adjusts concentration of alcohol to 60%, when to take supernatant to be concentrated into relative density be 80 DEG C
1.50, obtain medicinal extract；
C, above-mentioned medicinal extract is taken, volatile oil and vegetable oil that step a is obtained is added, the additive amount of vegetable oil accounts for medicinal extract and volatilization
The 2% of oily gross mass, mixing are ground 10 minutes with colloid mill, are stirred continuously, are cooled to room temperature, the Chinese medicine composition is filled
Enter in capsule housing to get the capsule.
The extraction of volatile oil is extracted using supercritical extraction in the step a.
It is extracted in the step b and uses macroporous resin method.
Instructions of taking: once in the morning and once at night, 2 tablets each time, warm water takes.10 days as a treatment course.
Embodiment 6:
A kind of preparation method of Chinese medicinal capsule that treating gout, steps are as follows:
A, by deal described in embodiment 3, take Caulis Perillae, solid carbon dioxide leech, cassia seed, lopseed, Poria cocos, radix scutellariae, radish seed and
Dysosma versipellis mixing, the water that 7 times of amounts are added impregnate 1.5 hours, extract 3 hours volatile oil, collect volatile oil, medical fluid filtration, medicine
Slag is spare；
B, it takes the dregs of a decoction of surplus stock medicinal material and the step a to mix, adds 75% ethyl alcohol, impregnate 1 hour, extract twice,
1.5 hours every time, for the first time plus 7 times were measured, second plus 7 times of amounts, combined extract, filtering；It concentrates filtrate to opposite
1.30 when density is 80 DEG C, alcohol precipitation twice, adjusts concentration of alcohol to 75%, when to take supernatant to be concentrated into relative density be 80 DEG C
1.30, obtain medicinal extract；
C, above-mentioned medicinal extract is taken, volatile oil and vegetable oil that step a is obtained is added, the additive amount of vegetable oil accounts for medicinal extract and volatilization
The 3% of oily gross mass, mixing are ground 10 minutes with colloid mill, are stirred continuously, are cooled to room temperature, the Chinese medicine composition is filled
Enter in capsule housing to get the capsule.
The extraction of volatile oil uses extraction by steam distillation in the step a.
It is extracted in the step b and uses high speed centrifugation method.
Instructions of taking: once in the morning and once at night, 2 tablets each time, warm water takes.10 days as a treatment course.
The above has been described in detail, described above, is only a preferred embodiment of the present invention, when cannot
It limit the scope of implementation of the present invention, i.e., it is all according to the made equivalent changes and modifications of the application range, it should still belong to covering scope of the present invention
It is interior.
Claims (3)
1. a kind of Chinese medicinal capsule for treating gout, it is characterised in that be formulated by the Chinese medicine material of following parts by weight: purple perilla
29 parts of stalk, 21 parts of solid carbon dioxide leech, 22 parts of cassia seed, 29 parts of lopseed, 16 parts of corn stigma, 19 parts of Poria cocos, 6 parts of radix scutellariae, radish seed 9
Part, prolong and entangles 9 parts recklessly, 6 parts of Radix Notoginseng, 6 parts of asarum, 9 parts of radix aconiti agrestis, 22 parts of fructus lycii, 11 parts of silkworm excrement, 13 parts of Ramulus Cinnamomi, rhizoma arisaematis 3
Part, 13 parts of Radix Angelicae Pubescentis, 10 parts of Dysosma versipellis, 10 parts of Chinese yam；The preparation method of the Chinese medicinal capsule the following steps are included:
A, Caulis Perillae, solid carbon dioxide leech, cassia seed, lopseed, Poria cocos, radix scutellariae, radish seed and Dysosma versipellis mixing are taken, 5-10 times is added and measures
Water impregnate 1-2 hour, extract 2-5 hour volatile oil, collection volatile oil, medical fluid filters, and the dregs of a decoction are spare；
B, it takes the dregs of a decoction of surplus stock medicinal material and the step a to mix, adds 60%-90% ethyl alcohol, impregnate 0.5-1.5 hours, mention
It takes twice, 1-2 hours each, for the first time plus 5-10 times is measured, and for the second time plus 5-10 times is measured, combined extract, filtering；Filtrate is subtracted
Pressure is concentrated into 1.10-1.50 when relative density is 80 DEG C, and alcohol precipitation twice, adjusts concentration of alcohol to 60%-90%, supernatant is taken to be concentrated
To relative density be 80 DEG C when 1.10-1.50, obtain medicinal extract；
C, above-mentioned medicinal extract is taken, volatile oil and vegetable oil that step a is obtained is added, the additive amount of vegetable oil accounts for medicinal extract and volatile oil
The 2-5% of gross mass, mixing are ground 10 minutes with colloid mill, are stirred continuously, are cooled to room temperature, the Chinese medicine composition is filled
Enter in capsule housing to get the capsule.
2. a kind of Chinese medicinal capsule for treating gout according to claim 1, it is characterised in that: volatilize in the step a
The extraction of oil is extracted using steam distillation or supercritical extraction.
3. a kind of Chinese medicinal capsule for treating gout according to claim 1, it is characterised in that: extracted in the step b
Using membrane separation technique, ultrafiltration, alcohol precipitation, high speed centrifugation or macroporous resin method.
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| CN101406584A (en) * | 2008-11-27 | 2009-04-15 | 蒋月芝 | Agent for treating gout |
| CN102526238A (en) * | 2012-02-09 | 2012-07-04 | 中国中医科学院中药研究所 | Chinese medicinal composition for preventing and treating rheumatoid arthritis |
| CN103933224A (en) * | 2014-04-30 | 2014-07-23 | 周晓明 | Traditional Chinese medicine composition for treating gout |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101406584A (en) * | 2008-11-27 | 2009-04-15 | 蒋月芝 | Agent for treating gout |
| CN102526238A (en) * | 2012-02-09 | 2012-07-04 | 中国中医科学院中药研究所 | Chinese medicinal composition for preventing and treating rheumatoid arthritis |
| CN103933224A (en) * | 2014-04-30 | 2014-07-23 | 周晓明 | Traditional Chinese medicine composition for treating gout |
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