CN105381388A - Traditional Chinese medicine composition for treating stomach discomfort and preparing method thereof - Google Patents

Traditional Chinese medicine composition for treating stomach discomfort and preparing method thereof Download PDF

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Publication number
CN105381388A
CN105381388A CN201510963975.9A CN201510963975A CN105381388A CN 105381388 A CN105381388 A CN 105381388A CN 201510963975 A CN201510963975 A CN 201510963975A CN 105381388 A CN105381388 A CN 105381388A
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parts
chinese medicine
medicine composition
stomach discomfort
herba
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李建敏
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9064—Amomum, e.g. round cardamom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237—Notopterygium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/62—Nymphaeaceae (Water-lily family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine composition for treating stomach discomfort and a preparing method thereof. The traditional Chinese medicine composition is prepared from, by weight, 3-5 parts of fructus amomi, 3-5 parts of belladonna herb, 6-8 parts of paederia scandens, 1-3 parts of asarum sieboldi, 8-10 parts of gorgon fruits, 8-12 parts of endothelium corneum gigeriae galli, 1-3 parts of notopterygium roots and 1-3 parts of myristica fragrans.

Description

A kind of Chinese medicine composition for the treatment of stomach discomfort and preparation method thereof
Technical field
The present invention relates to application and the preparation field of pharmaceuticals, relate to a kind of Chinese medicine composition for the treatment of stomach discomfort.
Background technology
Stomachache is also known as gastric abscess, refer to upper abdomen gastral cavilty portion nearly pit of the stomach place pain, the traditional Chinese medical science thinks that stomachache is that taste are impaired, the pain in gastral cavilty portion caused by qi and blood disorder, mainly with diseases caused by exogenous pathogenic factor cold-evil, the causes of disease such as the smooth and emptiness of spleen and stomach of injury due to diet, feelings will and causing, add that modern's eating raw food is cold and cool, pressure is excessive, the people suffering from stomachache gets more and more, the above abdominal pain such as acute gastritis, chronic gastritis, gastric ulcer, duodenal ulcer, functional digestive obstacle of doctor trained in Western medicine is cardinal symptom, belongs to Chinese medicine stomach discomfort scope.The method of current treatment stomach discomfort has Chinese traditional treatment and western medical treatment, western medical treatment is generally with amoxicillin+omeprazole+metronidazole, i.e. triple therapy, antacid infection is main, substantially can only alleviate or remove symptom, and long-term taking antibiotic, injure one's stomach gas, cause patient's anorexia, malnutrition, health is weaker.The traditional Chinese medical science is with cold and heat and asthenia and sthenia, coldheat complex, more common, but ignores taste prolonged deficiency, and long-pending silt is not smooth, only balances taste negative and positive not enough.Therefore cause unsatisfactory curative effect, Most patients feedback is only stomachache transference cure, but dietary amount does not increase, and digests and assimilates and do not improve.
Summary of the invention
One is the object of the present invention is to provide to treat stomachache, and the Chinese medicine composition that can improve appetite and digest and assimilate.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine composition for stomach discomfort, comprise the raw material of following weight portion: Fructus Amomi 3-5, Herba Belladonnae 3-5, fevervine 6-8, Herba Asari 1-3, Semen Euryales 8-10, Endothelium Corneum Gigeriae Galli 8-12, Rhizoma Et Radix Notopterygii 1-3, Semen Myristicae 1-3.
Preferably, comprise the raw material of following weight portion: Fructus Amomi 4, Herba Belladonnae 4, fevervine 7, Herba Asari 2, Semen Euryales 9, Endothelium Corneum Gigeriae Galli 10, Rhizoma Et Radix Notopterygii 2, Semen Myristicae 2.
The present invention also provides a kind of preparation method for the treatment of the Chinese medicine composition of stomach discomfort: comprise following process steps: the Fructus Amomi getting each weight portion by proportion relation, Herba Belladonnae, fevervine, Herba Asari, Semen Euryales, Endothelium Corneum Gigeriae Galli, Rhizoma Et Radix Notopterygii, Semen Myristicae; Add 70% ethanol to soak 15 minutes at 60 ~ 65 DEG C, reflux, extract, 2-3 time, each 1 hour, 100 order filters filter, and obtain extracting solution; Merge extractive liquid, reclaim under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution; By concentrated solution in 70-100 DEG C of spraying dry or oven dry, be ground into 70-100 object fine powder, Conventional compression or encapsulated after granulating, to obtain final product.
Prescription of the present invention is exquisite, each component synergism, analgesia of releiving, warming the stomach spleen invigorating, and desilting helps digestion, warming spleen and stomach for dispelling cold, especially applicable for cold syndrome of the stomach person with Spleen Deficiency.
Detailed description of the invention
Embodiment 1
(1) get Fructus Amomi 3 parts, Herba Belladonnae 3 parts, fevervine 6 parts, Herba Asari 1 part, Semen Euryales 8 parts, Endothelium Corneum Gigeriae Galli 8 parts, Rhizoma Et Radix Notopterygii 1 part, Semen Myristicae 1 part are for subsequent use;
(2) add 70% ethanol to soak 15 minutes at 60 DEG C, reflux, extract, 2 times, each 1 hour, 100 order filters filter, and obtain extracting solution; Merge extractive liquid, reclaim under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution; By concentrated solution in 70 DEG C of spraying dry or oven dry, be ground into 70 object fine powders, encapsulated after granulating, specification 0.45g/ grain. each 3 times of morning, noon and afternoon, bfore meals, each 3-5 grain.
Embodiment 2
(1) get Fructus Amomi 5 parts, Herba Belladonnae 5 parts, fevervine 8 parts, Herba Asari 3 parts, Semen Euryales 10 parts, Endothelium Corneum Gigeriae Galli 12 parts, Rhizoma Et Radix Notopterygii 3 parts, Semen Myristicae 3 parts are for subsequent use;
(2) add 70% ethanol to soak 15 minutes at 65 DEG C, reflux, extract, 3 times, each 1 hour, 100 order filters filter, and obtain extracting solution; Merge extractive liquid, reclaim under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution; By concentrated solution in 100 DEG C of spraying dry or oven dry, be ground into 100 object fine powders, encapsulated after granulating, specification 0.45g/ grain.
Embodiment 3
(1) get Fructus Amomi 4 parts, Herba Belladonnae 4 parts, fevervine 7 parts, Herba Asari 2 parts, Semen Euryales 9 parts, Endothelium Corneum Gigeriae Galli 10 parts, Rhizoma Et Radix Notopterygii 2 parts, Semen Myristicae 2 parts are for subsequent use;
(2) add 70% ethanol to soak 15 minutes at 62 DEG C, reflux, extract, 2 times, each 1 hour, 100 order filters filter, and obtain extracting solution; Merge extractive liquid, reclaim under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution; By concentrated solution in 80 DEG C of spraying dry or oven dry, be ground into 90 object fine powders, encapsulated after granulating, specification 0.45g/ grain.
Clinical efficacy data
1, the effect observation that has a stomach-ache is treated
1.1 objects: stomach discomfort observes 400 people, with gastralgia, hyperchlorhydria and the chronic dietary stagnation of QI, stool first hard rear half congealed, belch.
1.2 medicine compositions: Fructus Amomi 400 grams, Herba Belladonnae 400 grams, fevervine 700 grams, Herba Asari 200 grams, Semen Euryales 900 grams, Endothelium Corneum Gigeriae Galli 1000 grams, Rhizoma Et Radix Notopterygii 200 grams, Semen Myristicae 200 grams.
Said medicine is added 70% ethanol to soak 15 minutes at 62 DEG C, reflux, extract, 2 times, each 1 hour, 100 order filters filter, and obtain extracting solution; Merge extractive liquid, reclaim under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution; By concentrated solution in 80 DEG C of spraying dry or oven dry, be ground into 90 object fine powders, encapsulated after granulating, specification 0.45g/ grain, the morning, noon and afternoon are respectively once, bfore meals, each 3-5 grain.
1.3 curative effect judging standards:
Cure: gastralgia and other transference cures, x line, canel barium meal contrast examination or gastroscopy are normal.
Take a turn for the better: stomachache is alleviated, outbreak minimizing, other symptoms alleviate.
Do not heal: x line, canel barium meal contrast examination or gastroscopy are the same with premorbid, symptom is without improvement and take a turn for the better.
The routine effect for the treatment of stomachache 400
Use after 30 days, effective 291 examples of 400 example stomachache, take a turn for the better 89 examples, invalid 20 examples, obvious effective rate 73%, improvement rate 22%, total effective rate 95%.In use, all user all reflect that appetite improves, and appetite increases, and stool form and color make moderate progress.

Claims (3)

1. treat a Chinese medicine composition for stomach discomfort, it is characterized in that, comprise the raw material of following weight portion: Fructus Amomi 3-5, Herba Belladonnae 3-5, fevervine 6-8, Herba Asari 1-3, Semen Euryales 8-10, Endothelium Corneum Gigeriae Galli 8-12, Rhizoma Et Radix Notopterygii 1-3, Semen Myristicae 1-3.
2. a kind of Chinese medicine composition for the treatment of stomach discomfort according to claim 1, is characterized in that, comprise the raw material of following weight portion: Fructus Amomi 4, Herba Belladonnae 4, fevervine 7, Herba Asari 2, Semen Euryales 9, Endothelium Corneum Gigeriae Galli 10, Rhizoma Et Radix Notopterygii 2, Semen Myristicae 2.
3. a kind of preparation method for the treatment of the Chinese medicine composition of stomach discomfort according to claim 1 and 2: it is characterized in that comprising following process steps: the Fructus Amomi getting each weight portion by proportion relation, Herba Belladonnae, fevervine, Herba Asari, Semen Euryales, Endothelium Corneum Gigeriae Galli, Rhizoma Et Radix Notopterygii, Semen Myristicae; Add 70% ethanol to soak 15 minutes at 60 ~ 65 DEG C, reflux, extract, 2-3 time, each 1 hour, 100 order filters filter, and obtain extracting solution; Merge extractive liquid, reclaim under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution; By concentrated solution in 70-100 DEG C of spraying dry or oven dry, be ground into 70-100 object fine powder, Conventional compression or encapsulated after granulating, to obtain final product.
CN201510963975.9A 2015-12-21 2015-12-21 Traditional Chinese medicine composition for treating stomach discomfort and preparing method thereof Pending CN105381388A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177846A (en) * 2016-08-10 2016-12-07 李建敏 A kind of Chinese medicine composition treating erosive gastritis and preparation method thereof
CN110201047A (en) * 2019-07-18 2019-09-06 重庆市中药研究院 The preparation method of one breeder mistake boisiana extract

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1394629A (en) * 2002-07-10 2003-02-05 石淑纯 Chinese patent medicine for curing gastropathy
CN103751547A (en) * 2014-01-21 2014-04-30 四川绿禾药业有限公司 Traditional Chinese medicinal composition for reducing blood lipid and preparation method thereof
CN104083706A (en) * 2014-07-30 2014-10-08 董宝珍 Dandelion traditional Chinese medicinal decoction for treating gastritis and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1394629A (en) * 2002-07-10 2003-02-05 石淑纯 Chinese patent medicine for curing gastropathy
CN103751547A (en) * 2014-01-21 2014-04-30 四川绿禾药业有限公司 Traditional Chinese medicinal composition for reducing blood lipid and preparation method thereof
CN104083706A (en) * 2014-07-30 2014-10-08 董宝珍 Dandelion traditional Chinese medicinal decoction for treating gastritis and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177846A (en) * 2016-08-10 2016-12-07 李建敏 A kind of Chinese medicine composition treating erosive gastritis and preparation method thereof
CN110201047A (en) * 2019-07-18 2019-09-06 重庆市中药研究院 The preparation method of one breeder mistake boisiana extract

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Application publication date: 20160309