CN105343797A - Traditional Chinese medicine composition for curing stomach illness and preparation method thereof - Google Patents

Traditional Chinese medicine composition for curing stomach illness and preparation method thereof Download PDF

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Publication number
CN105343797A
CN105343797A CN201510925139.1A CN201510925139A CN105343797A CN 105343797 A CN105343797 A CN 105343797A CN 201510925139 A CN201510925139 A CN 201510925139A CN 105343797 A CN105343797 A CN 105343797A
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radix
chinese medicine
medicine composition
poria
rhizoma dioscoreae
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李建敏
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine composition for curing stomach illness, being prepared from the following raw materials in parts by weight: 1-3 of American ginseng, 3-5 of belladonna herb, 8-10 of rhizoma dioscoreae hypoglaucae, 1-3 of flos daturae, 6-8 of poria cocos, 3-5 of gardenia jasminoides, 1-3 of radix curcumae and 1-3 of scutellaria baicalensis.

Description

A kind of Chinese medicine composition being used for the treatment of gastropathy and preparation method thereof
Technical field
The present invention relates to application and the preparation field of pharmaceuticals, relate to a kind of Chinese medicine composition being used for the treatment of gastropathy.
Background technology
Stomachache is also known as gastric abscess, refer to upper abdomen gastral cavilty portion nearly pit of the stomach place pain, the traditional Chinese medical science thinks that stomachache is that taste are impaired, the pain in gastral cavilty portion caused by qi and blood disorder, mainly with diseases caused by exogenous pathogenic factor cold-evil, the causes of disease such as the smooth and emptiness of spleen and stomach of injury due to diet, feelings will and causing, add that autumn and winter surfeit is pungent dry strong, dry weather, the easy heat-dissipating of stomach, the people suffering from stomachache gets more and more; The above abdominal pain such as acute gastritis, chronic gastritis, gastric ulcer, duodenal ulcer, functional digestive obstacle of doctor trained in Western medicine is cardinal symptom, belongs to Chinese medicine gastropathy scope.The method of current treatment gastropathy has Chinese traditional treatment and western medical treatment, western medical treatment is generally with amoxicillin+omeprazole+metronidazole, i.e. triple therapy, antacid infection is main, substantially can only alleviate or remove symptom, and long-term taking antibiotic, injure one's stomach gas, cause patient's anorexia, malnutrition, health is weaker.The traditional Chinese medical science is with cold and heat and asthenia and sthenia, coldheat complex, more common, but ignores taste prolonged deficiency, and long-pending silt is not smooth, only balances taste negative and positive not enough.Therefore cause unsatisfactory curative effect, Most patients feedback is only stomachache transference cure, but dietary amount does not increase, and digests and assimilates and do not improve.
Summary of the invention
One is the object of the present invention is to provide to treat stomachache, and the Chinese medicine composition that can improve appetite and digest and assimilate.
The present invention is achieved through the following technical solutions:
Be used for the treatment of a Chinese medicine composition for gastropathy, comprise the raw material of following weight portion: Radix Panacis Quinquefolii 1-3, Herba Belladonnae 3-5, Rhizoma Dioscoreae Hypoglaucae 8-10, Flos Daturae 1-3, Poria 6-8, Fructus Gardeniae 3-5, Radix Curcumae 1-3, Radix Scutellariae 1-3.
Preferably, comprise the raw material of following weight portion: Radix Panacis Quinquefolii 2, Herba Belladonnae 4, Rhizoma Dioscoreae Hypoglaucae 9, Flos Daturae 2, Poria 7, Fructus Gardeniae 4, Radix Curcumae 2, Radix Scutellariae 2.
The present invention also provides a kind of preparation method being used for the treatment of the Chinese medicine composition of gastropathy: comprise following process steps: the Radix Panacis Quinquefolii getting each weight portion by proportion relation, Herba Belladonnae, Rhizoma Dioscoreae Hypoglaucae, Flos Daturae, Poria, Fructus Gardeniae, Radix Curcumae, Radix Scutellariae; Add 70% ethanol to soak 15 minutes at 60 ~ 65 DEG C, reflux, extract, 2-3 time, each 1 hour, 100 order filters filter, and obtain extracting solution; Merge extractive liquid, reclaim under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution; By concentrated solution in 70-100 DEG C of spraying dry or oven dry, be ground into 70-100 object fine powder, Conventional compression or encapsulated after granulating, to obtain final product.
Prescription of the present invention is exquisite, each component synergism, analgesia of releiving, clearing stomach spleen invigorating, broken silt removing food stagnancy, tonification is logical fall for gastric heat person with Spleen Deficiency especially applicable.
Detailed description of the invention
Embodiment 1
(1) get Radix Panacis Quinquefolii 1 part, Herba Belladonnae 3 parts, Rhizoma Dioscoreae Hypoglaucae 8 parts, Flos Daturae 1 part, 6 parts, Poria, Fructus Gardeniae 3 parts, Radix Curcumae 1 part, Radix Scutellariae 1 part are for subsequent use;
(2) add 70% ethanol to soak 15 minutes at 60 DEG C, reflux, extract, 2 times, each 1 hour, 100 order filters filter, and obtain extracting solution; Merge extractive liquid, reclaim under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution; By concentrated solution in 70 DEG C of spraying dry or oven dry, be ground into 70 object fine powders, encapsulated after granulating, specification 0.45g/ grain. each 3 times of morning, noon and afternoon, bfore meals, each 3-5 grain.
Embodiment 2
(1) get Radix Panacis Quinquefolii 3 parts, Herba Belladonnae 5 parts, Rhizoma Dioscoreae Hypoglaucae 10 parts, Flos Daturae 3 parts, 8 parts, Poria, Fructus Gardeniae 5 parts, Radix Curcumae 3 parts, Radix Scutellariae 3 parts are for subsequent use;
(2) add 70% ethanol to soak 15 minutes at 65 DEG C, reflux, extract, 3 times, each 1 hour, 100 order filters filter, and obtain extracting solution; Merge extractive liquid, reclaim under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution; By concentrated solution in 100 DEG C of spraying dry or oven dry, be ground into 100 object fine powders, encapsulated after granulating, specification 0.45g/ grain.
Embodiment 3
(1) get Radix Panacis Quinquefolii 2 parts, Herba Belladonnae 4 parts, Rhizoma Dioscoreae Hypoglaucae 9 parts, Flos Daturae 2 parts, 7 parts, Poria, Fructus Gardeniae 4 parts, Radix Curcumae 2 parts, Radix Scutellariae 2 parts are for subsequent use;
(2) add 70% ethanol to soak 15 minutes at 62 DEG C, reflux, extract, 2 times, each 1 hour, 100 order filters filter, and obtain extracting solution; Merge extractive liquid, reclaim under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution; By concentrated solution in 80 DEG C of spraying dry or oven dry, be ground into 90 object fine powders, encapsulated after granulating, specification 0.45g/ grain.
Clinical efficacy data
1, the effect observation that has a stomach-ache is treated
1.1 objects: gastropathy observes 600 people, with gastralgia, hyperchlorhydria and the chronic dietary stagnation of QI, stool first hard rear half congealed, belch, stomach has burn feeling.
1.2 medicine compositions: Radix Panacis Quinquefolii 200 grams, Herba Belladonnae 400 grams, Rhizoma Dioscoreae Hypoglaucae 900 grams, Flos Daturae 200 grams, 700 grams, Poria, Fructus Gardeniae 400 grams, Radix Curcumae 200 grams, Radix Scutellariae 200 grams.
Said medicine is added 70% ethanol to soak 15 minutes at 62 DEG C, reflux, extract, 2 times, each 1 hour, 100 order filters filter, and obtain extracting solution; Merge extractive liquid, reclaim under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution; By concentrated solution in 80 DEG C of spraying dry or oven dry, be ground into 90 object fine powders, encapsulated after granulating, specification 0.45g/ grain, the morning, noon and afternoon are respectively once, bfore meals, each 3-5 grain.
1.3 curative effect judging standards:
Cure: gastralgia and other transference cures, x line, canel barium meal contrast examination or gastroscopy are normal.
Take a turn for the better: stomachache is alleviated, outbreak minimizing, other symptoms alleviate.
Do not heal: x line, canel barium meal contrast examination or gastroscopy are the same with premorbid, symptom is without improvement and take a turn for the better.
The routine effect for the treatment of stomachache 600
Use after 30 days, effective 452 examples of 600 example stomachache, take a turn for the better 101 examples, invalid 47 examples, obvious effective rate 75%, improvement rate 17%, total effective rate 92%.In use, all user all reflect that appetite improves, and appetite increases, and stool form and color make moderate progress.

Claims (3)

1. be used for the treatment of a Chinese medicine composition for gastropathy, it is characterized in that, comprise the raw material of following weight portion: Radix Panacis Quinquefolii 1-3, Herba Belladonnae 3-5, Rhizoma Dioscoreae Hypoglaucae 8-10, Flos Daturae 1-3, Poria 6-8, Fructus Gardeniae 3-5, Radix Curcumae 1-3, Radix Scutellariae 1-3.
2. a kind of Chinese medicine composition being used for the treatment of gastropathy according to claim 1, is characterized in that, comprise the raw material of following weight portion: Radix Panacis Quinquefolii 3, Herba Belladonnae 4, Rhizoma Dioscoreae Hypoglaucae 9, Flos Daturae 2, Poria 7, Fructus Gardeniae 4, Radix Curcumae 2, Radix Scutellariae 2.
3. a kind of preparation method being used for the treatment of the Chinese medicine composition of gastropathy according to claim 1 and 2: it is characterized in that comprising following process steps: the Radix Panacis Quinquefolii getting each weight portion by proportion relation, Herba Belladonnae, Rhizoma Dioscoreae Hypoglaucae, Flos Daturae, Poria, Fructus Gardeniae, Radix Curcumae, Radix Scutellariae; Add 70% ethanol to soak 15 minutes at 60 ~ 65 DEG C, reflux, extract, 2-3 time, each 1 hour, 100 order filters filter, and obtain extracting solution; Merge extractive liquid, reclaim under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution; By concentrated solution in 70-100 DEG C of spraying dry or oven dry, be ground into 70-100 object fine powder, Conventional compression or encapsulated after granulating, to obtain final product.
CN201510925139.1A 2015-12-11 2015-12-11 Traditional Chinese medicine composition for curing stomach illness and preparation method thereof Pending CN105343797A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106138533A (en) * 2016-08-10 2016-11-23 李建敏 A kind of Chinese medicine composition treating flatulence pain and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1149465A (en) * 1995-10-27 1997-05-14 孔繁营 Traditional Chinese medicine metabolic powder
CN102018947A (en) * 2010-11-17 2011-04-20 朱长义 Medicine for diminishing inflammation and smoothing stomach

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1149465A (en) * 1995-10-27 1997-05-14 孔繁营 Traditional Chinese medicine metabolic powder
CN102018947A (en) * 2010-11-17 2011-04-20 朱长义 Medicine for diminishing inflammation and smoothing stomach

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张东锋等: "清化汤治疗脾胃湿热型慢性浅表性胃炎32 例", 《河南中医》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106138533A (en) * 2016-08-10 2016-11-23 李建敏 A kind of Chinese medicine composition treating flatulence pain and preparation method thereof

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Application publication date: 20160224