CN106074912A - A kind of Chinese medicine preparation treating cardiovascular and cerebrovascular disease - Google Patents

A kind of Chinese medicine preparation treating cardiovascular and cerebrovascular disease Download PDF

Info

Publication number
CN106074912A
CN106074912A CN201610699043.2A CN201610699043A CN106074912A CN 106074912 A CN106074912 A CN 106074912A CN 201610699043 A CN201610699043 A CN 201610699043A CN 106074912 A CN106074912 A CN 106074912A
Authority
CN
China
Prior art keywords
radix
cerebrovascular disease
chinese medicine
cardiovascular
medicine preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201610699043.2A
Other languages
Chinese (zh)
Other versions
CN106074912B (en
Inventor
李茂坤
彭宣文
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jingzhou Traditional Chinese Medicine Hospital
Original Assignee
Jingzhou Traditional Chinese Medicine Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jingzhou Traditional Chinese Medicine Hospital filed Critical Jingzhou Traditional Chinese Medicine Hospital
Priority to CN201610699043.2A priority Critical patent/CN106074912B/en
Publication of CN106074912A publication Critical patent/CN106074912A/en
Application granted granted Critical
Publication of CN106074912B publication Critical patent/CN106074912B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/346—Platycodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488—Pueraria (kudzu)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The present invention relates to a kind of Chinese medicine preparation treating cardiovascular and cerebrovascular disease, belong to Chinese herbal medicine preparation technology field.The Chinese medicine preparation of this treatment cardiovascular and cerebrovascular disease uses ten Six-element Chinese herbal medicine to make, and the present invention utilizes the comprehensive co-action for treating cardiovascular and cerebrovascular disease of ten Six-element crude drug, little to human body side effect, decocts without patient.There is Therapeutic Method easy, cheap, evident in efficacy feature.Prevention and treatment cardiovascular and cerebrovascular disease there is well effect.

Description

A kind of Chinese medicine preparation treating cardiovascular and cerebrovascular disease
Technical field
The present invention relates to a kind of Chinese medicine preparation treating cardiovascular and cerebrovascular disease, belong to Chinese herbal medicine preparation technology field.
Background technology
Cardiovascular and cerebrovascular disease is the commonly encountered diseases of a kind of serious threat human health, and within particularly more than 50 years old, middle-aged and elderly people is healthy Commonly encountered diseases, refer to the heart owing to hyperlipemia, hyperlipidemia, atherosclerosis and hypertension etc. are caused, brain and There is ischemic or hemorrhage in body tissue.It it has been the common and frequently-occurring disease since China's entrance aged society.People at present Great majority use the means of fall three-hypers to prevent and treat cardiovascular and cerebrovascular disease, but the most medication for blood pressure lowering, it is Make bloody path unimpeded by angiectatic mode.But after such medicine of life-time service, can make blood vessel that medicine tends to paralysis, Make effect of drugs reduce eventually or lost efficacy so that causing the hidden danger of cardiovascular and cerebrovascular disease not to be eliminated.
Summary of the invention
It is an object of the invention to: provide one to be formed by prepared from traditional Chinese medicines, for the pathogeny of cardiovascular and cerebrovascular disease, Blood circulation promoting and blood stasis dispelling, invigorating qi and dredging collateral, to reach the Chinese medicine preparation of the treatment cardiovascular and cerebrovascular disease for the treatment of both the principal and secondary aspects of a disease purpose.
The present invention is to realize above-mentioned purpose by following technical solution:
A kind of Chinese medicine preparation treating cardiovascular and cerebrovascular disease, it is characterised in that: it is made up of the raw material of Chinese medicine of following weight parts: (unit: gram)
Radix Astragali 18-22 Semen Persicae 4-8
Flos Carthami 4-8 Radix Angelicae Sinensis 4-8
Radix Paeoniae Rubra 4-8 Rhizoma Chuanxiong 4-8
Fructus Crataegi 12-16 Radix Salviae Miltiorrhizae 12-16
Pollen Typhae 4-8 Radix Achyranthis Bidentatae 6-10
Radix Rehmanniae 4-8 Radix Puerariae 8-12
Radix Platycodonis 4-8 stir-baked Fructus Aurantii in bran 4-8
Radix Bupleuri 4-8 Radix Glycyrrhizae 1-4
The preparation present invention treats Chinese medicine preparation preferred weight part ratio range of cardiovascular and cerebrovascular disease:
Radix Astragali 19-21 Semen Persicae 5-7
Flos Carthami 5-7 Radix Angelicae Sinensis 5-7
Radix Paeoniae Rubra 5-7 Rhizoma Chuanxiong 5-7
Fructus Crataegi 13-15 Radix Salviae Miltiorrhizae 13-15
Pollen Typhae 5-7 Radix Achyranthis Bidentatae 7-9
Radix Rehmanniae 5-7 Radix Puerariae 9-11
Radix Platycodonis 5-7 stir-baked Fructus Aurantii in bran 5-7
Radix Bupleuri 5-7 Radix Glycyrrhizae 1-3
The preparation present invention treats Chinese medicine preparation optimum weight part ratio range of cardiovascular and cerebrovascular disease:
The Radix Astragali 20 Semen Persicae 6
Flos Carthami 6 Radix Angelicae Sinensis 6
Radix Paeoniae Rubra 6 Rhizoma Chuanxiong 6
Fructus Crataegi 14 Radix Salviae Miltiorrhizae 14
Pollen Typhae 6 Radix Achyranthis Bidentatae 8
Radix Rehmanniae 6 Radix Puerariae 10
Radix Platycodonis 6 stir-baked Fructus Aurantii in bran 6
Radix Bupleuri 6 Radix Glycyrrhizae 2
The preparation method of the Chinese medicine preparation of above-mentioned treatment cardiovascular and cerebrovascular disease comprises the following steps:
1), by the Radix Astragali of above-mentioned weight portion, Semen Persicae, Flos Carthami, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Fructus Crataegi, Radix Salviae Miltiorrhizae, Pollen Typhae, Radix Achyranthis Bidentatae, the Radix Rehmanniae Huang, Radix Puerariae, Radix Platycodonis, stir-baked Fructus Aurantii in bran, Radix Bupleuri, Radix Glycyrrhizae, respectively boiling three times, 1.2 hours for the first time, for the second time, for the third time Each 1 hour, filter, collecting decoction；
2), above-mentioned gained decocting liquid is concentrated into according to a conventional method；The concentration adding concentrated medicament double weight after cooling is 60% Ethanol stir, after stand 24 little layereds at normal temperatures and pressures；
3), by step 2 supernatant take out, after reclaim ethanol according to a conventional method；Supernatant after reclaiming ethanol is centrifuged, and presses After conventional method concentrates, room temperature cools down, and filters；
4), at protein sugar and the sorbic acid of 1.6-2 part weight adding 1.6-2 part weight in the admixing medical solutions that step 3 processes Potassium；Add essence by the weight ratio of 100:3 afterwards and stir；Then add the purified water stirring of 1000 ml；Gained medicinal liquid divides according to quantity Bag, the Chinese medicine preparation finished product for the treatment of cardiovascular and cerebrovascular disease.
Character: this product is brown color liquid, and feeble QI, mildly bitter flavor are puckery, has the precipitation that can shake up a little.
Function cures mainly: benefiting QI for activating blood circulation.Prevention and apoplexy and coronary heart disease.And apoplexy sequela, coronary disease caused by blood stasis due to qi deficiency Sick, hyperlipemia.
The present invention is based on the research pathogenetic to cardiovascular and cerebrovascular disease of motherland's Chinese medicine and Therapeutic Principle, with reference to modern The scientific achievement of Chinese medical theory research, uses a large amount of Qi-tonifying drugs to match with a small amount of blood circulation promoting medicine by theory of Chinese medical science prescription so that it is tool There is the prosperous blood of gas, invigorate blood circulation and don't just hinder, playing effect of collaterals altogether.The Radix Astragali in the present invention, the vigour of big tonifying the spleen and stomach, Making the prosperous blood of gas, the stasis of blood goes network to lead to；Semen Persicae removing blood stasis row is stagnant and moisturizes；Flos Carthami blood circulation promoting and blood stasis dispelling, with pain relieving, is monarch drug altogether.Radix Angelicae Sinensis is longer than work Blood, double can nourish blood, and has blood stasis dispelling and non-blood trouble wonderful, with Radix Paeoniae Rubra, Rhizoma Chuanxiong principal drug assistance blood circulation promoting and blood stasis dispelling；Fructus Crataegi, Radix Salviae Miltiorrhizae, Pollen Typhae, Radix Achyranthis Bidentatae Promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing, conducting blood to flow downwards, is ministerial drug altogether.Radix Rehmanniae, Radix Puerariae nourish blood tonifying YIN, heat clearing and blood circulation promoting;Radix Platycodonis, parched with bran trifoliate orange Shell, one rise and one drop, the chest stuffiness relieving circulation of qi promoting;Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI, rises and reaches clear sun, Radix Platycodonis and the same use of stir-baked Fructus Aurantii in bran, is especially apt to regulating qi-flowing for activating stagnancy, makes Gas row then blood, is adjuvant drug.Radix Platycodonis energy medicine carrying are up, have concurrently and make medicine be used;Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, also for making medicine, close and With it, making blood stasis of blood activating QI row alive, the most all diseases more, and then reach the good result to cardiovascular and cerebrovascular disease treating both the principal and secondary aspects of a disease.
In the above-mentioned raw material of Chinese medicine component of the present invention, property feature and effect of every component raw material of Chinese medicine medicine are as follows:
The Radix Astragali: sweet, temperature.Return lung, spleen channel.Benefiting QI for strengthening the superficies, diuretic, evacuation of pus sore.For deficiency of spleen-QI and stomach-QI, insufficiency of vital energy and blood, Qi and blood deficiency.
Semen Persicae: bitter is flat.GUIXIN, liver, lung, large intestine channel.Promoting blood flow to regulate menstruation, loosening bowel to relieve constipation, relieving cough and asthma.For amenorrhea dysmenorrhea, Abdominal mass abdominal mass mass in the abdomen, lung abscess acute appendicitis, tumbling and swelling, dryness of the intestine constipation.
Flos Carthami: acrid in the mouth, warm in nature.GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, stimulates the menstrual flow.For amenorrhea, macule color is dark, traumatic injury congestive edema, bone Folding pain etc..
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature.Return liver, the heart, spleen channel.Replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Wither for blood deficiency Huang, asthenia cold abdominalgia, rheumatism arthromyodynia, traumatic injury, ulcer sores.
Radix Paeoniae Rubra: bitter in the mouth, cold nature.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.Nutrient blood, blood stasis amenorrhea, traumatic injury is entered for heat Damage, liver-heat.
Rhizoma Chuanxiong: pungent, temperature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, puerperal abdonimal pain, limb Body is numb, traumatic injury, wind-damp numbness.
Fructus Crataegi: sour, sweet, tepor.Enter spleen, stomach, Liver Channel.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For eating accumulation, dyspepsia is not changed, Stimulate the menstrual flow, amenorrhea.
Radix Salviae Miltiorrhizae: bitter in the mouth, is slightly cold.GUIXIN, pericardium, Liver Channel.Promoting blood flow to regulate menstruation, removing heat from blood eliminating carbuncle, nourishing blood to tranquillize the mind.For menstruation not Adjusting, abdominal mass abdominal mass is gathered, and unconsciousness due to high fever, painstaking effort are not supported.
Pollen Typhae: sweet, flat.Return liver, pericardium channel.Hemostasis, blood stasis dispelling, diuresis.For spitting blood, epistaxis, traumatic hemorrhage, amenorrhea leads to Warp, blood strangury and dry pain.
Radix Achyranthis Bidentatae: bitter, sour is flat.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome.For amenorrhea, dysmenorrhea, traumatic injury damages Wound, toothache, excessive rising of liver-YANG.
Radix Rehmanniae: sweet, bitter, cold.Enter the heart, liver, kidney channel.Clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, for thermal burn the moon liquid, interior-heat is quenched one's thirst, Consumption of YIN caused by febrile disease.
Radix Puerariae: sweet in the mouth, pungent, cool in nature.Attach to the lung and stomach meridians.Expelling pathogenic factors from muscles for reducing heat, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal.Do not solve for exterior syndrome, Diarrhea due to hypofunction of the spleen, interior-heat quenches one's thirst, exterior syndrome due to wind-cold.
Radix Platycodonis: bitter in the mouth, pungent, property is put down.Return lung meridian.Lung qi dispersing, sore-throat relieving, eliminate the phlegm, evacuation of pus.For cough with copious phlegm, lung abscess vomiting pus, expectorant Choke is stagnant, and exopathogen violates lung.
Stir-baked Fructus Aurantii in bran: bitter, pungent, sour, temperature.Return spleen, stomach warp.Regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.Coercing the stagnation of QI for breast, distension aches Bitterly, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention；Gastroptosis, proctoptosis, sub-official prolapses.
Radix Bupleuri: bitter, cold nature.Return liver, gallbladder meridian.Evacuation is brought down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang.For cold, fever, stagnation of liver-QI The stagnation of QI, depression of liver-QI, collapse of QI.
Radix Glycyrrhizae: the flat taste of property is sweet, GUIXIN, lung, spleen, stomach warp.Tool invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, relieving spasm to stop pain, the mitigation property of medicine it Merit.
The present invention having the beneficial effects that compared with prior art:
The Chinese medicine preparation of this treatment cardiovascular and cerebrovascular disease uses ten Six-element Chinese herbal medicine to make, and utilizes the comprehensive association of ten Six-element crude drug Same-action treatment cardiovascular and cerebrovascular disease, little to human body side effect, decoct without patient.There is Therapeutic Method easy, cheap, Feature evident in efficacy.Prevention and treatment cardiovascular and cerebrovascular disease there is well effect.
In order to the present invention curative effect to treatment cardiovascular and cerebrovascular disease is described, the present invention has carried out clinic to 100 patients and has controlled Treating and observe, its clinical data is as follows:
1, general data, 100 experimenters, suffer from cardiovascular and cerebrovascular disease, wherein 50 experimenters are compiled as observation group；50 realities The person of testing enrolls matched group, takes common drug and treats cardiovascular and cerebrovascular disease.
2, diagnosis basis:
1) heart and brain color ultrasound, electrocardiogram, the coherence check of CT sheet；
2) Chinese medical discrimination: deficiency of both the heart and spleen, disarmony between the heart and kidney, hyperactivity of heart-fire liver-yang are got angry, qi depression to blood stasis, deficiency of qi and blood, the hepatic and renal YIN deficiency.
3, efficacy assessment standard:
Curing: various Chinese and western medicine clinical symptoms are normal, auxiliary examination result support is cured；
Effective: various Chinese and western medicine clinical symptoms are obviously improved, auxiliary examination result is supported effective；
Effective: various Chinese and western medicine clinical symptoms are improved, auxiliary examination result is supported effectively；
Invalid: various Chinese and western medicine clinical symptoms are without improving；
Deteriorate: various Chinese and western medicine clinical symptoms substantially deteriorate.
4, observed data statistical table is followed the tracks of
Detailed description of the invention
Below embodiments of the present invention are described in detail:
Embodiment 1:
First each raw material of Chinese medicine is weighed by following each embodiment: (unit: gram)
The preparation method of the Chinese medicine preparation of the various embodiments described above treatment cardiovascular and cerebrovascular disease is:
By the Radix Astragali of above-mentioned weight portion, Semen Persicae, Flos Carthami, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Fructus Crataegi, Radix Salviae Miltiorrhizae, Pollen Typhae, Radix Achyranthis Bidentatae, Radix Rehmanniae, Pueraria lobota Root, Radix Platycodonis, stir-baked Fructus Aurantii in bran, Radix Bupleuri, Radix Glycyrrhizae, respectively boiling three times, 1.2 hours for the first time, for the second time, the most each 1 little Time, filter, collecting decoction.The decocting liquid of merging is concentrated into according to a conventional method；The dense of concentrated medicament double weight is added after cooling Degree be 60% ethanol stirring, after stand 24 little layereds at normal temperatures and pressures.Will layering after supernatant take out, after routinely Method reclaims ethanol；Supernatant after reclaiming ethanol is centrifuged, and concentrates according to a conventional method；It is subsequently adding the egg of 1.6-2 part weight White sugar and the potassium sorbate of 1.6-2 part weight；Add essence by the weight ratio of 100:3 afterwards and stir；Add the pure of 1000 ml Change water stirring；Gained medicinal liquid, by metering subpackage, obtains, the Chinese medicine preparation finished product for the treatment of cardiovascular and cerebrovascular disease.

Claims (3)

1. the Chinese medicine preparation treating cardiovascular and cerebrovascular disease, it is characterised in that: it is made up of the raw material of following weight parts:
Radix Astragali 18-22 Semen Persicae 4-8
Flos Carthami 4-8 Radix Angelicae Sinensis 4-8
Radix Paeoniae Rubra 4-8 Rhizoma Chuanxiong 4-8
Fructus Crataegi 12-16 Radix Salviae Miltiorrhizae 12-16
Pollen Typhae 4-8 Radix Achyranthis Bidentatae 6-10
Radix Rehmanniae 4-8 Radix Puerariae 8-12
Radix Platycodonis 4-8 stir-baked Fructus Aurantii in bran 4-8
Radix Bupleuri 4-8 Radix Glycyrrhizae 1-4.
The Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease the most according to claim 1, it is characterised in that: it is by following weight parts Raw material make:
Radix Astragali 19-21 Semen Persicae 5-7
Flos Carthami 5-7 Radix Angelicae Sinensis 5-7
Radix Paeoniae Rubra 5-7 Rhizoma Chuanxiong 5-7
Fructus Crataegi 13-15 Radix Salviae Miltiorrhizae 13-15
Pollen Typhae 5-7 Radix Achyranthis Bidentatae 7-9
Radix Rehmanniae 5-7 Radix Puerariae 9-11
Radix Platycodonis 5-7 stir-baked Fructus Aurantii in bran 5-7
Radix Bupleuri 5-7 Radix Glycyrrhizae 1-3.
The Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease the most according to claim 1, it is characterised in that: it is by following weight parts Raw material make:
The Radix Astragali 20 Semen Persicae 6
Flos Carthami 6 Radix Angelicae Sinensis 6
Radix Paeoniae Rubra 6 Rhizoma Chuanxiong 6
Fructus Crataegi 14 Radix Salviae Miltiorrhizae 14
Pollen Typhae 6 Radix Achyranthis Bidentatae 8
Radix Rehmanniae 6 Radix Puerariae 10
Radix Platycodonis 6 stir-baked Fructus Aurantii in bran 6
Radix Bupleuri 6 Radix Glycyrrhizae 2
The preparation method of the Chinese medicine preparation of above-mentioned treatment cardiovascular and cerebrovascular disease is:
1), by the Radix Astragali of above-mentioned weight portion, Semen Persicae, Flos Carthami, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Fructus Crataegi, Radix Salviae Miltiorrhizae, Pollen Typhae, Radix Achyranthis Bidentatae, the Radix Rehmanniae Huang, Radix Puerariae, Radix Platycodonis, stir-baked Fructus Aurantii in bran, Radix Bupleuri, Radix Glycyrrhizae, respectively boiling three times, 1.2 hours for the first time, for the second time, for the third time Each 1 hour, filter, collecting decoction；
2), above-mentioned gained decocting liquid is concentrated into according to a conventional method；The concentration adding concentrated medicament double weight after cooling is 60% Ethanol stir, after stand 24 little layereds at normal temperatures and pressures；
3), by step 2 supernatant take out, after reclaim ethanol according to a conventional method；Supernatant after reclaiming ethanol is centrifuged, and presses After conventional method concentrates, room temperature cools down, and filters；
4), at protein sugar and the sorbic acid of 1.6-2 part weight adding 1.6-2 part weight in the admixing medical solutions that step 3 processes Potassium；Add essence by the weight ratio of 100:3 afterwards and stir；Then add the purified water stirring of 1000 ml；Gained medicinal liquid divides according to quantity Bag, the Chinese medicine preparation finished product for the treatment of cardiovascular and cerebrovascular disease.
CN201610699043.2A 2016-08-22 2016-08-22 Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases Active CN106074912B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610699043.2A CN106074912B (en) 2016-08-22 2016-08-22 Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610699043.2A CN106074912B (en) 2016-08-22 2016-08-22 Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases

Publications (2)

Publication Number Publication Date
CN106074912A true CN106074912A (en) 2016-11-09
CN106074912B CN106074912B (en) 2020-01-24

Family

ID=58070225

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610699043.2A Active CN106074912B (en) 2016-08-22 2016-08-22 Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases

Country Status (1)

Country Link
CN (1) CN106074912B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648422A (en) * 2017-08-25 2018-02-02 刘志聪 A kind of Chinese medicine with blood circulation invigorating efficacies

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1096697A (en) * 1993-06-24 1994-12-28 乐清健生保健品有限公司 A kind of Chinese medicine electuary of preventing and treating cardiovascular and cerebrovascular disease
CN1465386A (en) * 2002-06-24 2004-01-07 李兆红 Chinese medicine preparation for treating cardio-cerebral vascular disease
CN102335380A (en) * 2010-07-20 2012-02-01 戴海清 Drug for treating cardiovascular and cerebrovascular diseases, and preparation method thereof
CN104606513A (en) * 2015-02-11 2015-05-13 青岛市市立医院 Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and preparation method of traditional Chinese medicine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1096697A (en) * 1993-06-24 1994-12-28 乐清健生保健品有限公司 A kind of Chinese medicine electuary of preventing and treating cardiovascular and cerebrovascular disease
CN1465386A (en) * 2002-06-24 2004-01-07 李兆红 Chinese medicine preparation for treating cardio-cerebral vascular disease
CN102335380A (en) * 2010-07-20 2012-02-01 戴海清 Drug for treating cardiovascular and cerebrovascular diseases, and preparation method thereof
CN104606513A (en) * 2015-02-11 2015-05-13 青岛市市立医院 Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and preparation method of traditional Chinese medicine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张印等: "补阳还五汤治疗心脑血管疾病的辨治分析", 《中国临床康复》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648422A (en) * 2017-08-25 2018-02-02 刘志聪 A kind of Chinese medicine with blood circulation invigorating efficacies

Also Published As

Publication number Publication date
CN106074912B (en) 2020-01-24

Similar Documents

Publication Publication Date Title
CN102579912B (en) Chinese medicinal capsules special for treating acute mastitis and preparation method thereof
CN102988870A (en) Oral liquid for treating diseases of liver, gall, stomach and intestinal canal
CN104127531A (en) Traditional Chinese medicine composition for treating enterogastritis and preparation method thereof
CN101934041A (en) Chinese medicinal herb for treating pleurisy
CN1141133C (en) Chinese medicine for treating hypertension
CN104758711A (en) Chinese herba preparation for treating pulmonary sarcoidosis and preparing method thereof
CN104353051A (en) Traditional Chinese medicine preparation for treating stomachache and preparation method thereof
CN1211434A (en) Oral liquid for resisting altitude stress and its preparation method
CN104367926A (en) Traditional Chinese medicine preparation for treating predawn diarrhea and preparation method thereof
CN106074912A (en) A kind of Chinese medicine preparation treating cardiovascular and cerebrovascular disease
CN103495103B (en) Medicament for promoting digestion and strengthening spleen
CN106267022A (en) A kind of medicine treating the viral myocarditis that deficiency of both QI and YIN causes and preparation method
CN101564522A (en) Chinese medicament for treating intercostal nerve pain and preparation method thereof
CN105056170A (en) Application of traditional Chinese medicine composition in preparing drug for treating acute gastritis
CN104367743A (en) Traditional Chinese medicine composition for treating bacillary dysentery and preparation method of traditional Chinese medicine composition
CN103520686A (en) Medicine for curing diarrhea caused by acquired immune deficiency syndrome
CN103432422B (en) Traditional Chinese medicine for treating chronic gastritis
CN103285130B (en) Chinese medicine composition for liver cancer treatment and preparing method thereof
CN104800792A (en) Traditional Chinese medicine preparation for treating reflux esophagitis and preparation method thereof
CN105663904A (en) Traditional Chinese medicine composition for treating peripheral neuritis
CN105435189A (en) Application of traditional Chinese medicine composition to preparation of drug for treating acute gastritis
CN105288143A (en) Traditional Chinese medicine composition for treating asthma
CN105381414A (en) Traditional Chinese medicine preparation for treating breast lumps and cystic hyperplasia and preparation method thereof
CN104857434A (en) Composition prepared from natural taurine and used for treating liver cirrhosis with portal hypertension as well as preparation method of composition
CN111329960A (en) Health wine for treating diabetes and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant