CN104857434A - Composition prepared from natural taurine and used for treating liver cirrhosis with portal hypertension as well as preparation method of composition - Google Patents
Composition prepared from natural taurine and used for treating liver cirrhosis with portal hypertension as well as preparation method of composition Download PDFInfo
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Abstract
The invention discloses composition prepared from natural taurine and used for treating liver cirrhosis with portal hypertension as well as a preparation method of the composition. The composition is characterized in that the traditional Chinese medicine preparation is prepared from raw materials in parts by weight as follows: 15-25 parts of taurine, 8-12 parts of danshen roots, 20-30 parts of orange fruits, 6-10 parts of largehead atractylodes rhizomes, 15-25 parts of glossy ganoderma, 8-12 parts of milkvetch roots, 14-18 parts of zedoray rhizomes, 6-10 parts of white peony roots, 4-8 parts of dried tangerine peels and 8-12 parts of corydalis roots. The medicine product has the significant treatment effect on the liver cirrhosis with portal hypertension, has functions of invigorating spleen, tonifying qi and supporting healthy energy, and is safe and stable in efficacy and free of toxic and side effects.
Description
[technical field]
The present invention relates to medical art, particularly a kind of composition and method of making the same of natural taurine preparation treatment Cirrhotic Portal Hypertension.
[technical background]
Cause the cause of disease of liver cirrhosis a lot, the Etiological of different regions is also not quite similar, common with hepatitis liver cirrhosis disease in China, is secondly Schistosomal cirrhosis disease, alcoholic cirrhosis disease etc.Clinical often show as with lassitude and weak, loss of appetite, symptom of digestive tract, bleeding tendency and anemia, endocrine secretly pitch-dark etc.If do not treated in time, often bring out the multiple disease having a strong impact on Health and Living such as hepatorenal syndrome, upper gastrointestinal hemorrhage, hepatic encephalopathy, electrolyte and acid base imbalance, primary hepatocarcinoma etc., clinical onset rate has the trend constantly risen in recent years.But modern medicine is for clinical a certain symptom treatment, often falls flat, and can not find suitable Therapeutic Method.
[summary of the invention]
In view of above content; the invention provides the composition and method of making the same of a kind of natural taurine preparation treatment Cirrhotic Portal Hypertension; the compositions of natural taurine preparation treatment Cirrhotic Portal Hypertension provided by the present invention can treat Cirrhotic Portal Hypertension effectively; there is invigorating the spleen and benefiting QI, strengthening the body resistance; drug effect safety and stability, without any side effects.
Technical scheme of the present invention is:
A compositions for natural taurine preparation treatment Cirrhotic Portal Hypertension, described compositions is made primarily of the raw material of following weight parts: taurine 15 ~ 25 parts, Radix Salviae Miltiorrhizae 8 ~ 12 parts, Fructus Aurantii 20 ~ 30 parts, the Rhizoma Atractylodis Macrocephalae 6 ~ 10 parts, Ganoderma 15 ~ 25 parts, the Radix Astragali 8 ~ 12 parts, Rhizoma Curcumae 14 ~ 18 parts, the Radix Paeoniae Alba 6 ~ 10 parts, Pericarpium Citri Reticulatae 4 ~ 8 parts, Rhizoma Corydalis 8 ~ 12 parts.
Further, described compositions is made primarily of the raw material of following weight parts: taurine 15 ~ 20 parts, Radix Salviae Miltiorrhizae 8 ~ 10 parts, Fructus Aurantii 20 ~ 25 parts, the Rhizoma Atractylodis Macrocephalae 6 ~ 8 parts, Ganoderma 15 ~ 20 parts, the Radix Astragali 8 ~ 10 parts, Rhizoma Curcumae 14 ~ 16 parts, the Radix Paeoniae Alba 6 ~ 8 parts, Pericarpium Citri Reticulatae 4 ~ 6 parts, Rhizoma Corydalis 8 ~ 10 parts.
Further, described compositions is made primarily of the raw material of following weight parts: taurine 20 ~ 25 parts, Radix Salviae Miltiorrhizae 10 ~ 12 parts, Fructus Aurantii 25 ~ 30 parts, the Rhizoma Atractylodis Macrocephalae 8 ~ 10 parts, Ganoderma 20 ~ 25 parts, the Radix Astragali 10 ~ 12 parts, Rhizoma Curcumae 16 ~ 18 parts, the Radix Paeoniae Alba 8 ~ 10 parts, Pericarpium Citri Reticulatae 6 ~ 8 parts, Rhizoma Corydalis 10 ~ 12 parts.
Further, described compound preparation is made primarily of the raw material of following weight parts: taurine 20 parts, Radix Salviae Miltiorrhizae 10 parts, Fructus Aurantii 25 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, Ganoderma 20 parts, the Radix Astragali 10 parts, Rhizoma Curcumae 14 parts, the Radix Paeoniae Alba 8 parts, Pericarpium Citri Reticulatae 6 parts, Rhizoma Corydalis 10 parts.
Further, described compound preparation is made primarily of the raw material of following weight parts: taurine 23 parts, Radix Salviae Miltiorrhizae 11 parts, Fructus Aurantii 27 parts, the Rhizoma Atractylodis Macrocephalae 9 parts, Ganoderma 23 parts, the Radix Astragali 11 parts, Rhizoma Curcumae 15 parts, the Radix Paeoniae Alba 9 parts, Pericarpium Citri Reticulatae 7 parts, Rhizoma Corydalis 11 parts.
Further, described taurine is natural taurine.
The compositions its preparation method of natural taurine preparation treatment Cirrhotic Portal Hypertension of the present invention presses the conventional formulation technique of relevant dosage form; add appropriate amount of auxiliary materials and make corresponding dosage form, make oral liquid, granule, capsule, tablet or other pharmaceutically useful dosage form.
The preparation method of the oral liquid of the compositions of above-described natural taurine preparation treatment Cirrhotic Portal Hypertension, 1) get taurine, Radix Salviae Miltiorrhizae, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Ganoderma, the Radix Astragali, Rhizoma Curcumae, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Rhizoma Corydalis; 2) according to after weight classification composition, 5-8 is added water doubly by gross weight; 3) decoct three times, each 2 hours, collecting decoction, filter; 4) add adjuvant, make oral liquid.
The preparation method of other dosage forms of compositions of above-described natural taurine preparation treatment Cirrhotic Portal Hypertension, is characterized in that, 1) get taurine, Radix Salviae Miltiorrhizae, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Ganoderma, the Radix Astragali, Rhizoma Curcumae, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Rhizoma Corydalis; 2) according to after weight classification composition, 5-8 is added water doubly by gross weight; 3) decoct three times, each 2 hours, collecting decoction, filter; 4) be concentrated into the thick paste that relative density is 1.28-1.30, then dry, pulverize into fine powder below 80 degree; 5) add adjuvant, mixing, makes capsule, tablet, granule.
Further, described adjuvant accounts for 35% of total composition, wherein starch oar 10%, dextrin 10%, lactose 5%, dry starch 5%, stearic acid 2%, mannitol 1%, Talcum acid 2%.
In the present invention, Chinese medicine details is as follows:
Taurine, can participate in maintaining organismic internal environment stable state, plays important regulating action, have unique physiological property in the normal performance of the system physiological functions such as maincenter digestion reproduction immunity and endocrine.
Radix Salviae Miltiorrhizae, nature and flavor are sweet, bitter, are slightly cold, and have blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, and clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, lump in the abdomen, gathers, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea, amenorrhea, skin infection swells and ache.
Fructus Aurantii, property is bitter, pungent, sour, warm, has effect of regulating the flow of QI to ease the stomach, the stagnant relieving distension of row, and cure mainly the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, the diseases such as uterine prolapse.
The Rhizoma Atractylodis Macrocephalae, has another name called: the winter Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis Macrocephalae, winter art, has adjustment gastrointestinal motility function, antiulcer, protect the liver, enhancing human body immunity function, anti-stress, enhancing hemopoietic function, antioxidation, slow down aging, blood sugar lowering, anticoagulation, the effect such as antitumor.
Rhizoma Curcumae, nature and flavor are pungent, bitter, temperature.Return liver, spleen channel.Cure mainly coagulation of QI-blood, trusted subordinate's distending pain, lump in the abdomen, gathers, and dyspepsia does not disappear, women's blood stasis amenorrhea, and traumatic injury is had a pain, and has promoting QI circulation for relieving depression, removing blood stasis with potent drugs, the function of pain relieving.
The Radix Paeoniae Alba, cool in nature, bitter in the mouth is sour, is slightly cold, and has the effects such as blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain, astringing YIN to stop sweating, be applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction are anxious, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band.
The Radix Astragali, can enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.Jishengshenqiwan albuminuria can be eliminated, strengthen myocardial contraction, regulate blood sugar content.
Ganoderma, warm in nature, lightly seasoned, gas is special, and mildly bitter flavor is puckery.Malaise, insomnia, palpitation with fear.This product sweet in the mouth is put down, and enters heart channel, can reinforcing the heart blood, the beneficial motive, tranquilizing mind, therefore availablely controls the disease such as malaise caused by insufficiency of vital energy and blood, lack of preservation of spirit, insomnia, palpitation with fear, dreaminess, forgetful, the tired Mental fatigue of body, lack of appetite.
Pericarpium Citri Reticulatae, bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.
Rhizoma Corydalis, Rhizoma Corydalis acrid in the mouth, hardship, warm in nature.There is promoting blood circulation to remove blood stasis, the function of regulating QI to relieve pain.For whole body each portion qi depression to blood stasis pain, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain.
The present invention adopts above technical scheme, compared with prior art, has the following advantages: by the compositions of natural taurine preparation treatment Cirrhotic Portal Hypertension, have invigorating the spleen and benefiting QI, strengthening the body resistance, drug effect safety and stability, without any side effects.Below in conjunction with detailed description of the invention, technical scheme of the present invention is described further.
[detailed description of the invention]
Embodiment 1
A compositions for natural taurine preparation treatment Cirrhotic Portal Hypertension, described compositions forms (every part of 1g) primarily of following component according to weight classification: taurine 15 parts, Radix Salviae Miltiorrhizae 8 parts, Fructus Aurantii 20 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, Ganoderma 15 parts, the Radix Astragali 8 parts, Rhizoma Curcumae 14 parts, the Radix Paeoniae Alba 6 parts, Pericarpium Citri Reticulatae 4 parts, Rhizoma Corydalis 8 parts; After above weight classification composition, make oral liquid according to the following steps: the water 1) adding 5 times by the gross weight of taurine, Radix Salviae Miltiorrhizae, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Ganoderma, the Radix Astragali, Rhizoma Curcumae, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Rhizoma Corydalis; 2) decoct three times, each 2 hours, collecting decoction, filter; 3) add adjuvant, make oral liquid.Wherein, described adjuvant accounts for 35% of total composition, and comprises starch oar 10%, dextrin 10%, lactose 5%, dry starch 5%, stearic acid 2%, mannitol 1%, Talcum acid 2%.
In addition, by following steps, the compositions of above weight portion is made capsule, tablet, granule: the water 1) adding 5 times by the gross weight of taurine, Radix Salviae Miltiorrhizae, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Ganoderma, the Radix Astragali, Rhizoma Curcumae, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Rhizoma Corydalis; 2) decoct three times, each 2 hours, collecting decoction, filter; 3) decocting liquid after filtration is concentrated into the thick paste that relative density is 1.28-1.30, then dry, pulverize into fine powder below 80 degree; 5) add adjuvant, mixing, makes capsule, tablet, granule.
Embodiment 2
A compositions for natural taurine preparation treatment Cirrhotic Portal Hypertension, described compositions forms (every part of 1g) primarily of following component according to weight classification: taurine 20 parts, Radix Salviae Miltiorrhizae 10 parts, Fructus Aurantii 25 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, Ganoderma 20 parts, the Radix Astragali 10 parts, Rhizoma Curcumae 14 parts, the Radix Paeoniae Alba 8 parts, Pericarpium Citri Reticulatae 6 parts, Rhizoma Corydalis 10 parts; After above weight classification composition, make oral liquid according to the following steps: the water 1) adding 6 times by the gross weight of taurine, Radix Salviae Miltiorrhizae, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Ganoderma, the Radix Astragali, Rhizoma Curcumae, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Rhizoma Corydalis; 2) decoct three times, each 2 hours, collecting decoction, filter; 3) add adjuvant, make oral liquid.Described adjuvant accounts for 35% of total composition, and comprises starch oar 10%, dextrin 10%, lactose 5%, dry starch 5%, stearic acid 2%, mannitol 1%, Talcum acid 2%.
In addition, by following steps, the compositions of above weight portion is made capsule, tablet, granule: the water 1) adding 6 times by the gross weight of taurine, Radix Salviae Miltiorrhizae, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Ganoderma, the Radix Astragali, Rhizoma Curcumae, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Rhizoma Corydalis; 2) decoct three times, each 2 hours, collecting decoction, filter; 3) decocting liquid after filtration is concentrated into the thick paste that relative density is 1.28-1.30, then dry, pulverize into fine powder below 80 degree; 5) add adjuvant, mixing, makes capsule, tablet, granule.
Embodiment 3
A compositions for natural taurine preparation treatment Cirrhotic Portal Hypertension, described compositions forms (every part of 1g) primarily of following component according to weight classification: taurine 23 parts, Radix Salviae Miltiorrhizae 11 parts, Fructus Aurantii 27 parts, the Rhizoma Atractylodis Macrocephalae 9 parts, Ganoderma 23 parts, the Radix Astragali 11 parts, Rhizoma Curcumae 15 parts, the Radix Paeoniae Alba 9 parts, Pericarpium Citri Reticulatae 7 parts, Rhizoma Corydalis 11 parts; After above weight classification composition, make oral liquid according to the following steps: the water 1) adding 7 times by the gross weight of taurine, Radix Salviae Miltiorrhizae, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Ganoderma, the Radix Astragali, Rhizoma Curcumae, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Rhizoma Corydalis; 2) decoct three times, each 2 hours, collecting decoction, filter; 3) add adjuvant, make oral liquid.Described adjuvant accounts for 35% of total composition, and comprises starch oar 10%, dextrin 10%, lactose 5%, dry starch 5%, stearic acid 2%, mannitol 1%, Talcum acid 2%.
In addition, by following steps, the compositions of above weight portion is made capsule, tablet, granule: the water 1) adding 7 times by the gross weight of taurine, Radix Salviae Miltiorrhizae, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Ganoderma, the Radix Astragali, Rhizoma Curcumae, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Rhizoma Corydalis; 2) decoct three times, each 2 hours, collecting decoction, filter; 2) decocting liquid after filtration is concentrated into the thick paste that relative density is 1.28-1.30, then dry, pulverize into fine powder below 80 degree; 3) add adjuvant, mixing, makes capsule, tablet, granule.
Embodiment 4
A kind of compositions of natural taurine preparation treatment Cirrhotic Portal Hypertension, described compositions forms (every part of 1g) primarily of following component according to weight classification: taurine 25 parts, Radix Salviae Miltiorrhizae 12 parts, Fructus Aurantii 30 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Ganoderma 25 parts, the Radix Astragali 12 parts, Rhizoma Curcumae 18 parts, the Radix Paeoniae Alba 10 parts, Pericarpium Citri Reticulatae 8 parts, Rhizoma Corydalis 12 parts, after above weight classification composition, make oral liquid according to the following steps: the water 1) adding 8 times by the gross weight of taurine, Radix Salviae Miltiorrhizae, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Ganoderma, the Radix Astragali, Rhizoma Curcumae, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Rhizoma Corydalis; 2) decoct three times, each 2 hours, collecting decoction, filter; 3) add adjuvant, make oral liquid.Described adjuvant accounts for 35% of total composition, and comprises starch oar 10%, dextrin 10%, lactose 5%, dry starch 5%, stearic acid 2%, mannitol 1%, Talcum acid 2%.
In addition, by following steps, the compositions of above weight portion is made capsule, tablet, granule: the water 1) adding 8 times by the gross weight of taurine, Radix Salviae Miltiorrhizae, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Ganoderma, the Radix Astragali, Rhizoma Curcumae, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Rhizoma Corydalis, each 2 hours, collecting decoction, filtered; 3) decocting liquid after filtration is concentrated into the thick paste that relative density is 1.28-1.30, then dry, pulverize into fine powder below 80 degree; 5) add adjuvant, mixing, makes capsule, tablet, granule.
Case 1
Deep certain, female, 34 years old, people from Heng County, hepatitis B.In April, 2012, because occurring that obvious abdominal distention is with symptoms such as general weaknesses, through checking that being diagnosed as " acute hepatitis B " accepts treatment 2 months in hospital, mainly give the liver protecting and ALT lowering treatment.But do not give the antiviral therapy of system.In autumn then, above-mentioned symptom again occurs and increases the weight of, and find that albumin declines in local hospital inspection, transaminase raises, spleen increases, and thicken, portal vein is broadening, be diagnosed as chronic hepatitis b cirrhosis, successively the hospital that a few family is large carry out treating but fashion time bad, for the Therapeutic Method of looking for novelty is examined then.Take Chinese medicine composition of the present invention after 1 month, malaise and abdominal distention sense disappear, right hypochondriac region pain obviously alleviates, appetite increases, and takes again Chinese medicine composition of the present invention after 2 months, has rosy cheeks, glossy, take again Chinese medicine composition of the present invention after 6 months, every inspection is all normal, follows up a case by regular visits to so far, without recurrence.
Case 2
Lin, man, 41 years old, people from Xixiangtang District, suffered from hepatitis B, liver cirrhosis is had a surplus for 5 years, recent aggravation, hepatalgia, patient's dim complexion, in Huang, band is blue or green, lassitude, goes here and there bitterly under two sides of body, bitter taste xerostomia, anorexia, constipation, two stringy,thready and rapid pulse, the tip of the tongue limit is red, and yellow fur is sliding, and two more so.Take Chinese medicine composition of the present invention after 1 month, the lower pain relief of hepatic region, two sides of body, take again Chinese medicine composition of the present invention after 1 month, pain disappears substantially, spirit is gradually shaken, and takes again Chinese medicine composition of the present invention 5 months, and every inspection is all normal, symptom all disappears, and follows up a case by regular visits to so far, without recurrence.
Case 3
Zhang, female, 33 years old, Baise of Guangxi people, suffered from hepatitis before 10 years and heals through treatment.The first half of this year, time sense dizzy weak, distension and fullness in the abdomen, right flank is not relaxed after food more very, and large dry stool is secret, dry mouth, lustreless complexion, and tongue is partially light red, tongue is few, stringy and thready pulse, and on inspection, A/G is inverted, and B ultrasonic is pointed out: liver cirrhosis.Take Chinese medicine composition of the present invention after 1 month, dizzy weak obvious improvement, abdominal distention disappears substantially, takes again Chinese medicine composition of the present invention after 3 months, and complexion takes a turn for the better, routine blood test is normal, spirit is gradually shaken, and take again Chinese medicine composition of the present invention every inspection in 5 months all normal, symptom all disappears, follow up a case by regular visits to so far, without recurrence.
Case 4
Wu, man, 49 years old, people from Yulin City of Guangxi Zhuang Autonomous, suffered from hepatitis B great three positive, and treatment loses effect for many years, and within 2013, certain hospitalize 1 year, spend tens thousand of unit, the state of an illness increased the weight of on the contrary, develops into liver cirrhosis.Liver function test is pointed out: paddy third turn of enzyme 1514U/L, total bilirubin 244umol/L, glutamate-oxaloacetate transaminase 700U/L.Time medical, patient's complexion is black dull, myasthenia of limbs, anorexia, feels sick, vomiting, abdominal distention, hepatalgia, regular diarrhoea, and yellow fur is sliding, stringy,thready and rapid pulse.Take Chinese medicine composition of the present invention 20, hepatalgia is significantly alleviated, check liver function, three transaminase's indexs have dropped to more than 1400, bilirubin Tui Liao120Ge unit, take again Chinese medicine composition of the present invention after 2 months, appetite increases, abdominal distention, diarrhoea is basic to disappear, and again checks liver function close to normal, takes again Chinese medicine composition of the present invention after 6 months, liver function test is completely normal, and above-mentioned symptom all disappears.
Case 5
Huang, man, 54 years old, people from Guangxi Hechi, there is shallow complexion, limbs fatigue, hepatalgia, deficiency of QI with disinclination to talk in February, 2012 in patient, Zeng Yin suffers from hepatitis B successively four hospitalization, leaves hospital after alleviation.5th recurrence at the beginning of 2013 12 months, the poor effect that takes traditional Chinese medicine and diagnose and look into abnormal liver function at that time, B ultrasonic prompting liver cirrhosis.Patient's hepatalgia, skin has purpura, and occasionally have hematemesis, pale complexion, extremities being not warm, lassitude, pale tongue with white fur, tongue has petechia, deep-thready pulse.Take Chinese medicine composition of the present invention 1 month, hepatalgia is significantly alleviated, and skin purpura is disappeared gradually, and hematemesis disappears, take again Chinese medicine composition of the present invention after 2 months, appetite increases, and hepatalgia is greatly alleviated, and check liver function is close to normal, take again Chinese medicine composition of the present invention after 6 months, liver function test is completely normal, and above-mentioned symptom all disappears, and liver cirrhosis is cured.
Case 6
Poplar, female, 37 years old, people from Qinzhou City, patient suffered from chronic hepatitis before 3 years, checked lower 3 centimetres of hepatic region rib, lower 5 centimetres of xiphoid-process, liver pain, controls, in the spring in this year, start a complete rest through treatment state of an illness end.Liver pain, appetite goes down day by day, enters abdominal distention after meal, and be on tenterhooks, waist such as heave hand is tightly restrainted, and is difficult to squat down, headache aversion to cold, greenish-yellow complexion, and cheek is very thin, and eye born of the same parents and the micro-existing edema of biped, dimly pale tongue, edge is slightly red, and the yellowish folder of tongue is white, and root is slightly thick greasy.Take Chinese medicine composition of the present invention after 15 days, edema is decorporated, and hepatalgia is alleviated, take again Chinese medicine composition of the present invention after 2 months, abdominal distention disappears substantially, and stool is normal, can go to work once in a while, spirit is gradually shaken, and takes again Chinese medicine composition of the present invention and has a surplus half a year, every inspection is all normal, have rosy cheeks, body weight increases, and symptom all disappears, be back on the job, normally work.
Clinical findings
The product of medicine of the present invention is used for the treatment of Cirrhotic Portal Hypertension Be very effective, has invigorating the spleen and benefiting QI, strengthening the body resistance, and drug effect safety and stability is without any side effects.Treating liver cirrhosis with liver disease drug of the present invention, is a kind of simple, safety, curative effect reliably Therapeutic Method.But hepatopathy is a kind of chronic disease of complexity, must take by the course for the treatment of, just can reach Comprehensive Treatment object.
Claims (10)
1., by a compositions for natural taurine preparation treatment Cirrhotic Portal Hypertension, it is characterized in that: described compositions is made primarily of the raw material of following weight parts: taurine 15 ~ 25 parts, Radix Salviae Miltiorrhizae 8 ~ 12 parts, Fructus Aurantii 20 ~ 30 parts, the Rhizoma Atractylodis Macrocephalae 6 ~ 10 parts, Ganoderma 15 ~ 25 parts, the Radix Astragali 8 ~ 12 parts, Rhizoma Curcumae 14 ~ 18 parts, the Radix Paeoniae Alba 6 ~ 10 parts, Pericarpium Citri Reticulatae 4 ~ 8 parts, Rhizoma Corydalis 8 ~ 12 parts.
2. the compositions of natural taurine preparation treatment Cirrhotic Portal Hypertension according to claim 1, is characterized in that: described compositions is made primarily of the raw material of following weight parts: taurine 15 ~ 20 parts, Radix Salviae Miltiorrhizae 8 ~ 10 parts, Fructus Aurantii 20 ~ 25 parts, the Rhizoma Atractylodis Macrocephalae 6 ~ 8 parts, Ganoderma 15 ~ 20 parts, the Radix Astragali 8 ~ 10 parts, Rhizoma Curcumae 14 ~ 16 parts, the Radix Paeoniae Alba 6 ~ 8 parts, Pericarpium Citri Reticulatae 4 ~ 6 parts, Rhizoma Corydalis 8 ~ 10 parts.
3. the compositions of natural taurine preparation treatment Cirrhotic Portal Hypertension according to claim 1, is characterized in that: described compositions is made primarily of the raw material of following weight parts: taurine 20 ~ 25 parts, Radix Salviae Miltiorrhizae 10 ~ 12 parts, Fructus Aurantii 25 ~ 30 parts, the Rhizoma Atractylodis Macrocephalae 8 ~ 10 parts, Ganoderma 20 ~ 25 parts, the Radix Astragali 10 ~ 12 parts, Rhizoma Curcumae 16 ~ 18 parts, the Radix Paeoniae Alba 8 ~ 10 parts, Pericarpium Citri Reticulatae 6 ~ 8 parts, Rhizoma Corydalis 10 ~ 12 parts.
4. the compositions of natural taurine preparation treatment Cirrhotic Portal Hypertension according to claim 1, is characterized in that: described compound preparation is made primarily of the raw material of following weight parts: taurine 20 parts, Radix Salviae Miltiorrhizae 10 parts, Fructus Aurantii 25 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, Ganoderma 20 parts, the Radix Astragali 10 parts, Rhizoma Curcumae 14 parts, the Radix Paeoniae Alba 8 parts, Pericarpium Citri Reticulatae 6 parts, Rhizoma Corydalis 10 parts.
5. the compositions of natural taurine preparation treatment Cirrhotic Portal Hypertension according to claim 1, is characterized in that: described compound preparation is made primarily of the raw material of following weight parts: taurine 23 parts, Radix Salviae Miltiorrhizae 11 parts, Fructus Aurantii 27 parts, the Rhizoma Atractylodis Macrocephalae 9 parts, Ganoderma 23 parts, the Radix Astragali 11 parts, Rhizoma Curcumae 15 parts, the Radix Paeoniae Alba 9 parts, Pericarpium Citri Reticulatae 7 parts, Rhizoma Corydalis 11 parts.
6. the compositions of natural taurine preparation treatment Cirrhotic Portal Hypertension according to claim 1, is characterized in that: described taurine is natural taurine.
7., as claimed in claim 1 by a preparation method for the compositions of natural taurine preparation treatment Cirrhotic Portal Hypertension, it is characterized in that: described compositions can make granule, capsule, tablet or oral liquid.
8. the preparation method of the compositions of natural taurine preparation treatment Cirrhotic Portal Hypertension according to claim 7, is characterized in that: this preparation method comprises the following steps:
1) taurine, Radix Salviae Miltiorrhizae, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Ganoderma, the Radix Astragali, Rhizoma Curcumae, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Rhizoma Corydalis is got;
2) according to after weight classification composition, 5-8 is added water doubly by gross weight;
3) decoct three times, each 2 hours, collecting decoction, filter;
4) add adjuvant, make oral liquid.
9. the preparation method of the compositions of natural taurine preparation treatment Cirrhotic Portal Hypertension according to claim 7, is characterized in that: this preparation method comprises the following steps:
1) taurine, Radix Salviae Miltiorrhizae, Fructus Aurantii, the Rhizoma Atractylodis Macrocephalae, Ganoderma, the Radix Astragali, Rhizoma Curcumae, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Rhizoma Corydalis is got;
2) according to after weight classification composition, 5-8 is added water doubly by gross weight;
3) decoct three times, each 2 hours, collecting decoction, filter;
4) decocting liquid after filtration is concentrated into the thick paste that relative density is 1.28-1.30, then dry, pulverize into fine powder below 80 degree;
5) add adjuvant, mixing, makes capsule, tablet, granule.
10. the preparation method of the compositions of natural taurine preparation treatment Cirrhotic Portal Hypertension according to claim 7; it is characterized in that: described adjuvant accounts for 35% of total composition, and comprise starch oar 10%, dextrin 10%, lactose 5%, dry starch 5%, stearic acid 2%, mannitol 1%, Talcum acid 2%.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510252316.4A CN104857434B (en) | 2015-05-18 | 2015-05-18 | A kind of composition that treatment Cirrhotic Portal Hypertension is prepared with natural taurine and preparation method thereof |
| PCT/CN2015/000769 WO2016183703A1 (en) | 2015-05-18 | 2015-11-09 | Composition for treating portal hypertension of cirrhosis, and preparation method therefor |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510252316.4A CN104857434B (en) | 2015-05-18 | 2015-05-18 | A kind of composition that treatment Cirrhotic Portal Hypertension is prepared with natural taurine and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2016183703A1 (en) * | 2015-05-18 | 2016-11-24 | 邓鑫 | Composition for treating portal hypertension of cirrhosis, and preparation method therefor |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101297888A (en) * | 2008-05-29 | 2008-11-05 | 北京凯因生物技术有限公司 | Medicament composition and preparation thereof |
| CN101884761A (en) * | 2009-05-15 | 2010-11-17 | 张春 | Medicament for treating cirrhosis and portal hypertension |
| CN103191379A (en) * | 2013-05-07 | 2013-07-10 | 张金梅 | Traditional Chinese medicinal composition for treating cirrhosis |
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| CN1044974C (en) * | 1994-06-17 | 1999-09-08 | 殷广全 | Anti- hepatitis B preparation |
| CN1053832C (en) * | 1996-08-29 | 2000-06-28 | 李安治 | Chinese patent drug for cirrhosis of liver |
| CN102125630B (en) * | 2011-02-17 | 2013-03-13 | 邓鑫 | Traditional Chinese medicinal preparation for treating chronic hepatitis B and preparation method thereof |
| CN102671056B (en) * | 2012-01-10 | 2013-11-20 | 河南科技大学 | Chinese medicinal composition for treating hepatitis and preparation method thereof |
| CN104857434B (en) * | 2015-05-18 | 2018-06-08 | 邓鑫 | A kind of composition that treatment Cirrhotic Portal Hypertension is prepared with natural taurine and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101297888A (en) * | 2008-05-29 | 2008-11-05 | 北京凯因生物技术有限公司 | Medicament composition and preparation thereof |
| CN101884761A (en) * | 2009-05-15 | 2010-11-17 | 张春 | Medicament for treating cirrhosis and portal hypertension |
| CN103191379A (en) * | 2013-05-07 | 2013-07-10 | 张金梅 | Traditional Chinese medicinal composition for treating cirrhosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2016183703A1 (en) * | 2015-05-18 | 2016-11-24 | 邓鑫 | Composition for treating portal hypertension of cirrhosis, and preparation method therefor |
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| WO2016183703A1 (en) | 2016-11-24 |
| CN104857434B (en) | 2018-06-08 |
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