CN104922547A - Traditional Chinese medicine used for treating functional dyspepsia - Google Patents
Traditional Chinese medicine used for treating functional dyspepsia Download PDFInfo
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- CN104922547A CN104922547A CN201510323921.6A CN201510323921A CN104922547A CN 104922547 A CN104922547 A CN 104922547A CN 201510323921 A CN201510323921 A CN 201510323921A CN 104922547 A CN104922547 A CN 104922547A
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Abstract
The invention relates to a traditional Chinese medicine used for treating the functional dyspepsia. The traditional Chinese medicine comprises, by weight, 10 parts of endothelium corneum gigeriae galli, 6 parts of elecampane, 10 parts of betel nuts, 15 parts of medicated leaven, 15 parts of scorched hawthorn fruit, 10 parts of poria cocos, 15 parts of semen raphani, 30 parts of fried rice sprouts and 30 parts of roasted malt. Clinical trials prove that the functional dyspepsia can be safely and effectively treated through the traditional Chinese medicine.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of functional dyspepsia.
Background technology
Functional dyspepsia is modal a kind of functional gastrointestinal disorder clinically also known as dyspepsia, the clinical manifestation of atypism, mainly contains upper abdominal pain, big belly, early full, inappetence, Nausea and vomiting etc.Can occur separately or with one group of symptom.Sustainable or the recurrent exerbation of symptom, accumulative more than 12 weeks in course of disease December more than month or in the past.Functional dyspepsia belongs to the traditional Chinese medical science " feeling of fullness " category, and it is in the majority that dyspepsia belongs to syndrome of spleen-deficiency and QI-stagnation, and how because of exopathogen invasion and attack, injury due to diet, the looking angry strongly fragrant mechanism of qi of reason such as overstrain is pondered over, feelings will is not smooth, impairing the spleen and stomach, taste disorder in ascending and descending, causes gastrointestinal dysfunction.
Statistics display, the sickness rate of primary disease accounts for gastrointestinal special outpatient clinic patient's more than 30%.Pathogenesis for this kind of disease is clinical at present still to be imperfectly understood, and studies display for many years, and the generation of primary disease is mainly subject to the impact of following three aspects, first psychology, spiritual undesirable element; It two is bad dietary habit; It three is impacts of environment.Modern medicine study shows, digestive tract power receives the adjustment of polyneural system, psychologic factors, gut hormone and gastrointestinal local immunity etc., when body occurs that the bad mental such as anxiety, depression affects, just vagus nerve, cholinergic nerve can be suppressed, thus inhibit gastrointestinal function, and then bow I plays the generation of functional dyspepsia.For the treatment of this kind of disease, current doctor trained in Western medicine is advocated based on Comprehensive Treatments such as acid suppression, motivator, antidepressants, but it is unsatisfactory to put into practice display effect for many years.Therefore, develop a kind of newly, safety, effective medicine has important clinical value and industrial value.
Medical material present Research involved in the present invention is as follows:
Endothelium Corneum Gigeriae Galli [another name] ENDOTHELIUM CORNEUM GIGERIAE GALLI.[source] this product is the dry inner wall of sandbag of Phasianidae animal man chicken.After killing chicken, take out chicken gizzard, peel inwall (first do not wash with water, otherwise difficulty being peeled off and easily fragmentation) while hot immediately, cleaning, drying.[nature and flavor] are sweet, flat.[return through] returns spleen, stomach, small intestinal, urinary bladder channel.[function cures mainly] invigorating the stomach and promoting digestion, arresting seminal emission.Do not disappear for food stagnation, vomiting dysentery, infantile malnutrition, the enuresis, seminal emission.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] is insufficiency of the spleen careful clothes of the nothing person of amassing.[extracts] " China's book on Chinese herbal medicine ".
The Radix Aucklandiae [another name] Saussurea lappa Clarke, Radix Aucklandiae (Radix Vladimiriae).[source] this product is the dry root of the feverfew Radix Aucklandiae.Autumn, season in winter two excavate, and removing silt and fibrous root, cutting, large vertical profile again becomes lobe, hits rough bark after drying.[nature and flavor] are pungent, bitter, temperature.[return through] returns spleen, stomach, large intestine, three burnt, gallbladder meridians.[function cures mainly] promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.For breast gastral cavity distending pain, heavy after dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).For stomachache of having loose bowels.[usage and dosage] takes orally: decoct soup, 1.5 ~ 6g.The careful clothes of [attention] deficiency of YIN deficiency of body fluid person.[extracts] " China's book on Chinese herbal medicine ".
Semen Arecae [another name] bulky jade, Bin Men, blue or green son, state horse, Bing Nan, sharp Bin, Cor Gigeriae Galli Semen Arecae.[source] this product is the dry mature seed of babassu Semen Arecae.Gather at the beginning of spring Mo to autumn mature fruit, after decocting in water, dry, removing peel, takes out seed, dry.[nature and flavor] are bitter, pungent, temperature.[return through] returns stomach, large intestine channel.[function cures mainly] killing insect and eliminating accumulation, sending down the abnormal ascending QI, row water, preventing the attack (or recurrence) of malaria.For cestode, ascarid, fasciolopsiasis buski, abdominal pain due to worm stagnation, stagnant dysentery, tenesmus, edema beriberi, malaria.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] disease belongs to deficiency of vital energy person and avoids it.Taste are empty, though there is stagnant person to use; Cardiac and abdominal pain should not be used without staying knot and non-worm to attack the person of stinging; Disease non-epidemic pathogenic factors from mountains person should not use.All diseases belong to deficiency of both YIN and YANG, deficiency of QI in middle-JIAO, and parenteral stops up stagnant, dyspepsia distension person, knows and avoided.[extracts] " China's book on Chinese herbal medicine ".
Massa Medicata Fermentata [another name] Massa Medicata Fermentata, six songs.The medicines such as [source] is Herba polygoni hydropiperis, Herba Artemisiae Annuae, Semen Armeniacae Amarum add flour or wheat bran mixed after, through the herbal leaven of fermentation.[nature and flavor] sweet, acrid, warm.[return through] enters spleen, stomach warp.[function cures mainly] invigorating the spleen and regulating the stomach, helps digestion in adjusting.Control retention of food and drink, feeling of stuffiness in chest abdominal distention, vomiting dysentery, postnatal blood stasis is suffered from abdominal pain, and children's's enlarged abdomen heavily fortified point is long-pending.[usage and dosage] takes orally: decoct soup, 10 ~ 15g.[attention] deficiency of spleen-YIN, stomach-fire Sheng person should not use; Can be fallen tire, and anemia of pregnant woman should eat less.[extracts] " China's book on Chinese herbal medicine ".
[another name] Qiu, fine strain of millet prunus mume (sieb.) sieb.et zucc., loom, Mus look into, Yang Qiu, red pawl real, Tang Qiu, red Chinese date, Fructus Pyri Pashiae fruit, Ziziphi Spinosae to Fructus Crataegi (parched to brown), and in nasal mucus group, Fructus Kaki short, bristly hair or beard, mountain, fruit, thatch short, bristly hair or beard, monkey short, bristly hair or beard, Rhododendron simsii Planch. fruit, Fructus mail micromali, tamarind seed, Pyrusussuriensis, acid are looked into.The fruit that [source] is rosaceous plant Fructus Crataegi or Crataegi cuneatae.Pluck during fruit maturation in autumn.Fructus Crataegi adopt after, crosscut becomes the thin slice of thick 1.5 ~ 3 millimeters, dries immediately.Crataegi cuneatae adopt after, dry, or dry again after being pressed into pie.Commodity Fructus Crataegi slice are called " Fructus Crataegi "; Crataegi cuneatae is called " Fructus Crataegi cuneatae ".[nature and flavor] acid is sweet, tepor.[return through] enters spleen, stomach, Liver Channel.[function cures mainly] helps digestion long-pending, dissipating blood stasis blood, expelling tenia.Control meat to amass, lump in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia after-pains in puerperal, lochiorrhea, children's's breast food is stagnated.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, stomach alkane distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain, hyperlipidemia.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] polyphagia consumption gas, damages tooth, easily hungry, on an empty stomach and thin and weak people or void avoid it after being ill.[extracts] " China's book on Chinese herbal medicine ".
Poria [another name] Poria, Cortex Sclerotii Poriae, Poria block, Poria, Poria.[source] this product is the dry sclerotia of On Polyporaceae Poria.Excavate more than 7 ~ JIUYUE, dig out rear removing silt, bank up after " diaphoresis ", spread out and dry in the air to dry tack free, then " diaphoresis ", after extremely now scatter and disappear in wrinkle, the large portion of internal moisture for several times repeatedly, dry in the shade, be called " Poria "; Or fresh Poria is pressed different parts cutting, dry in the shade, be called " Cortex Sclerotii Poriae " and " Poria block ".[nature and flavor] are sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[attention] deficiency and coldness essence slides or collapse of QI person avoids clothes.[extracts] " China's book on Chinese herbal medicine ".
Semen Raphani [source] this product is the mature seed of crucifer Radix Raphani.The 5-8 month, there is the abundant maturation of fruit to gather and dry, lay seed, removing impurity, put the storage of dry place.[nature and flavor] are pungent, sweet, flat.[return through] returns spleen, stomach, lung, large intestine channel.[function cures mainly] dyspepsia and intestinal stasis relieving, lowering the adverse-rising QI to resolve phlegm.Main stagnation of QI due to dyspepsia, distension and fullness in the abdomen, diarrhoea, heavy after dysentery; Cough ant phlegm, QI rising in reverse order dyspnea with fullness of the chest.[usage and dosage] 5 ~ 10g.[extracts] " China's book on Chinese herbal medicine ".
Fructus Setariae Germinatus (parched) [another name] tiller rice, paddy tiller, rice tiller, Fructus Oryzae Germinatus.[source] this product is that the mature fruit of grass foxtail millet obtains through drying of germinateing.After foxtail millet paddy is soaked in water, keeps suitable epidemic disaster, when fibrous root grows to about 6mm, dry or cold drying.[nature and flavor] are sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] help digestion and in, spleen benefiting and stimulating the appetite.Do not disappear for food stagnation, abdominal distention halitosis, weakness of the spleen and stomach, not hungry lack of appetite.Fructus Setariae Germinatus (parched) relatively helps digestion, for not hungry lack of appetite.It is stagnant that Fructus Setariae Germinatus (parched to brown) is apt to eliminate indigestion, do not disappear for stagnant.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[attention] gastroptosis person avoids use.[extracts] " China's book on Chinese herbal medicine ".
Fructus Hordei Germinatus (parched) [another name] Fructus Hordei Vulgaris tiller, wheat tiller, Fructus Hordei Vulgaris hair, Fructus Hordei Germinatus.[source] this product is that the mature fruit of grass Fructus Hordei Vulgaris obtains through drying of germinateing.After wheat grain is soaked in water, keeps suitable epidemic disaster, when plumelet grows to about 0.5cm, dry or cold drying.[nature and flavor] are sweet, flat.[return through] returns spleen, stomach warp.[function cures mainly] promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back newborn relieving distension.Do not disappear for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, milk smoulders, distending pain of the breast, and women weans.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[attention] all phlegm-fire asthma and anemia of pregnant woman, can't use.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of functional dyspepsia, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing functional dyspepsia.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of functional dyspepsia, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Endothelium Corneum Gigeriae Galli 10 parts, the Radix Aucklandiae 6 parts, Semen Arecae 10 parts, Massa Medicata Fermentata 15 parts, Fructus Crataegi (parched to brown) 15 parts, 10 parts, Poria, Semen Raphani 15 parts, Fructus Setariae Germinatus (parched) 30 parts, Fructus Hordei Germinatus (parched) 30 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects the routine patients with functional dyspepsia of outpatient service patients with functional dyspepsia 60 between year December of October ~ 2014 in 2013 altogether, wherein man 27 example, female 33 example; 19 ~ 59 years old age, average (37.2 ± 1.5) year; The course of disease 6 months ~ 22 years, average course of disease is (5.0 ± 3.9) year.Be divided into observation group and matched group two groups at random, often organize each 30 examples.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
(1) at least have with next symptom: post-prandial fullness is uncomfortable, early full sense, upper abdominal pain, upper abdomen burn feeling, and does not have the organic disease can explaining above-mentioned symptom, and before diagnosis, symptom occurs at least 6 months.(2) following the person in charge and two must be met with disease last time: primary symptom: abdominal part distending pain, two side of body distensions; Secondary disease: painful abdominal mass plug does not relax, susceptible to lose temper due to restlessness, thin white fur of tongue, feelings will is not smooth, sighing frequently etc.
Inclusive criteria: (1) meets functional dyspepsia Western medicine diagnose standard and the diagnostic criteria of dyspepsia TCM syndrome; (2) age >=18 years old; (3) Hospital Ethical Committee's examination & verification person of passing through; (4) patient's informed consent, and signature Informed Consent Form person.
Exclusion standard: (1) gastroscopy does not find organic disease patient, as: esophagus, stomach ulcer, tumor etc.; (2) laboratory, x line, ultrasound diagnosis get rid of patient without liver and gall, pancreatic diseases; (3) serious organ's Diseases such as the heart, brain, lung, liver, kidney, hemopoietic system are merged; (4) gestation and women breast-feeding their children; (5) digestive tract power and sensory function medicine patient was taken in nearly 1 month; (6) ethanol, drug dependence patient; (7) patient signing Informed Consent Form is not agreed to.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.It within 15 days, is 1 course for the treatment of.
The oral motilium 10mg of matched group, every day 3 times 15 days is 1 course for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Effective: the gastrointestinal symptoms such as the glutted discomfort of patient's epigastrium, nausea and vomiting all disappear;
Effective: above-mentioned symptom alleviates or takes a turn for the better;
Invalid: above-mentioned symptom increases the weight of sign without improving or having.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment functional dyspepsia, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Endothelium Corneum Gigeriae Galli 10 grams, the Radix Aucklandiae 6 grams, Semen Arecae 10 grams, Massa Medicata Fermentata 15 grams, Fructus Crataegi (parched to brown) 15 grams, 10 grams, Poria, Semen Raphani 15 grams, Fructus Setariae Germinatus (parched) 30 grams, Fructus Hordei Germinatus (parched) 30 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of functional dyspepsia.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: Endothelium Corneum Gigeriae Galli 10 grams, the Radix Aucklandiae 6 grams, Semen Arecae 10 grams, Massa Medicata Fermentata 15 grams, Fructus Crataegi (parched to brown) 15 grams, 10 grams, Poria, Semen Raphani 15 grams, Fructus Setariae Germinatus (parched) 30 grams, Fructus Hordei Germinatus (parched) 30 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of functional dyspepsia.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: Endothelium Corneum Gigeriae Galli 10 grams, the Radix Aucklandiae 6 grams, Semen Arecae 10 grams, Massa Medicata Fermentata 15 grams, Fructus Crataegi (parched to brown) 15 grams, 10 grams, Poria, Semen Raphani 15 grams, Fructus Setariae Germinatus (parched) 30 grams, Fructus Hordei Germinatus (parched) 30 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of functional dyspepsia.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (1)
1. one kind is used for the treatment of the Chinese medicine of functional dyspepsia, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Endothelium Corneum Gigeriae Galli 10 parts, the Radix Aucklandiae 6 parts, Semen Arecae 10 parts, Massa Medicata Fermentata 15 parts, Fructus Crataegi (parched to brown) 15 parts, 10 parts, Poria, Semen Raphani 15 parts, Fructus Setariae Germinatus (parched) 30 parts, Fructus Hordei Germinatus (parched) 30 parts.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109730981A (en) * | 2019-03-07 | 2019-05-10 | 张春梅 | For treating anorexia, dyspeptic Traditional Chinese medicine composition patch, preparation and its application |
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| CN1397334A (en) * | 2002-07-24 | 2003-02-19 | 桂林漓江制药有限公司 | Medicine for infant to invigorate function of spleen and expel stagnation and its preparing process |
| CN101417090A (en) * | 2008-11-21 | 2009-04-29 | 冯书德 | Pills formulation capable of invigorating the stomach and relieving stagnancy and preparation method thereof |
| CN103623296A (en) * | 2013-12-03 | 2014-03-12 | 天津中新药业集团股份有限公司达仁堂制药厂 | Preparation method of extract of traditional Chinese medicine with functions of regulating qi, relieving pain, invigorating stomach and promoting digestion |
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- 2015-06-12 CN CN201510323921.6A patent/CN104922547A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1397334A (en) * | 2002-07-24 | 2003-02-19 | 桂林漓江制药有限公司 | Medicine for infant to invigorate function of spleen and expel stagnation and its preparing process |
| CN101417090A (en) * | 2008-11-21 | 2009-04-29 | 冯书德 | Pills formulation capable of invigorating the stomach and relieving stagnancy and preparation method thereof |
| CN103623296A (en) * | 2013-12-03 | 2014-03-12 | 天津中新药业集团股份有限公司达仁堂制药厂 | Preparation method of extract of traditional Chinese medicine with functions of regulating qi, relieving pain, invigorating stomach and promoting digestion |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109730981A (en) * | 2019-03-07 | 2019-05-10 | 张春梅 | For treating anorexia, dyspeptic Traditional Chinese medicine composition patch, preparation and its application |
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