CN106138922A - A kind of Chinese medicine formula treating rectal cancer - Google Patents

A kind of Chinese medicine formula treating rectal cancer Download PDF

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Publication number
CN106138922A
CN106138922A CN201510169680.4A CN201510169680A CN106138922A CN 106138922 A CN106138922 A CN 106138922A CN 201510169680 A CN201510169680 A CN 201510169680A CN 106138922 A CN106138922 A CN 106138922A
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parts
chinese medicine
rectal cancer
medicine formula
agkistrodon
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CN201510169680.4A
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李湘
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Individual
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Abstract

The present invention relates to a kind of Chinese medicine formula treating rectal cancer, belong to traditional Chinese medicine technology, its efficacy component is made up of the component of following weight portion: Radix Rehmanniae 10 parts-20 parts, Agkistrodon 10 parts-20 parts, the Radix Astragali 10 parts-20 parts, Rhizoma Sparganii 10 parts-14 parts, Scolopendra 5 parts-15 parts, vine of Flos Lonicerae 4 parts-8 parts, Semen Sterculiae Lychnophorae 5 parts-15 parts.Pharmaceutical composition tool benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, anticancer effect of the present invention, it is possible to effectively treat rectal cancer, strengthen patient's appetite, enhancing immunity.

Description

A kind of Chinese medicine formula treating rectal cancer
[technical field]
The present invention relates to technical field of Chinese medicine, particularly to a kind of Chinese medicine formula treating rectal cancer.
[technical background]
At present in the field of Chinese medicines for the treatment of rectal cancer, there is the weak point of two aspects: one is that therapeutic effect is obvious not, Two is that the comparison that takes effect is slow.So that large quantities of rectal cancer patients or can not with treatment Chinese medicine suppression tumor growth, or operation cut Except rear tumor recurrence, shifting, spread, this is unsatisfied with by patient and family members thereof.
For posed problems above, the invention provides a kind of Chinese medicine treating rectal cancer, it can efficiently solve conventional rectum In cancer treatment, effect is obvious not, the problem that the comparison that takes effect is slow, and the present invention is effective, instant effect, has that effect is notable, treats Imitate definite advantage.
[summary of the invention]
It is an object of the invention to provide a kind of Chinese medicine formula that can effectively treat rectal cancer, provided by the present invention is treatment The Chinese medicine formula of rectal cancer can be with invigorating the spleen and benefiting QI, the logical fall of YIN nourishing.Can preferably treat rectal cancer, have no side effect, safety can Lean on.
Technical scheme is as follows:
A kind of Chinese medicine formula treating rectal cancer, it is characterised in that: the active ingredient of described pharmaceutical composition is prepared by following raw material Form:
Radix Rehmanniae, Agkistrodon, the Radix Astragali, Rhizoma Sparganii, Scolopendra, vine of Flos Lonicerae, Semen Sterculiae Lychnophorae.
Further, it is preferable to the active ingredient of described pharmaceutical composition is prepared from by the raw material of following weight portion:
Radix Rehmanniae 10 parts-20 parts, Agkistrodon 10 parts-20 parts, the Radix Astragali 10 parts-20 parts,
Rhizoma Sparganii 10 parts-14 parts, Scolopendra 5 parts-15 parts, vine of Flos Lonicerae 4 parts-8 parts, Semen Sterculiae Lychnophorae 5 parts-15 parts.
Further, it is preferable to the active ingredient of described pharmaceutical composition is prepared from by the raw material of following weight portion:
Radix Rehmanniae 15 parts, Agkistrodon 15 parts, the Radix Astragali 15 parts,
Rhizoma Sparganii 12 parts, Scolopendra 10 parts, vine of Flos Lonicerae 6 parts, Semen Sterculiae Lychnophorae 10 parts.
The dosage form of any of the above-described pharmaceutical composition is preferably oral liquid, granule, capsule or tablet.
The preparation method of any of the above-described pharmaceutical composition, it is characterised in that take by weight ratio Radix Rehmanniae, Agkistrodon, the Radix Astragali, Rhizoma Sparganii, Scolopendra, vine of Flos Lonicerae and Semen Sterculiae Lychnophorae, add water 4-5 times by gross weight, and warm fire decocts 2-3 hour, closes after decocting twice And decocting liquid, filter, make oral liquid.
The preparation method of any of the above-described pharmaceutical composition, it is characterised in that take by weight ratio Radix Rehmanniae, Agkistrodon, the Radix Astragali, Rhizoma Sparganii, Scolopendra, vine of Flos Lonicerae and Semen Sterculiae Lychnophorae, add water 4-5 times by gross weight, and warm fire decocts 2-3 hour, closes after decocting twice And decocting liquid, filter;It is concentrated into the paste that relative density is 1.32-1.40, then dry, pulverize into fine powder below 80 degree, add Enter adjuvant, mixing, make granule.
The preparation method of any of the above-described pharmaceutical composition, it is characterised in that take by weight ratio Radix Rehmanniae, Agkistrodon, the Radix Astragali, Rhizoma Sparganii, Scolopendra, vine of Flos Lonicerae and Semen Sterculiae Lychnophorae, add water 4-5 times by gross weight, and warm fire decocts 2-3 hour, closes after decocting twice And decocting liquid, filter;It is concentrated into the paste that relative density is 1.32-1.40, then dry, pulverize into fine powder below 80 degree, add Enter adjuvant, mixing, make tablet.
The raw material of Chinese medicine medicine details used in the present invention is as follows:
Radix Rehmanniae, removing blood stasis, circulation of qi promoting, removing food stagnancy, pain relieving.Control abdominal mass accumulation, coagulation of QI-blood, trusted subordinate's pain, swollen pain, warp under the side of body Closing, postnatal blood stasis is suffered from abdominal pain, and traumatic injury, skin ulcer swells hard.
Agkistrodon, sweet in the mouth, cold in nature.Returning stomach, lung, large intestine, bladder warp, heat-clearing and toxic substances removing, eliminating carbuncle dissipates straight, promoting urination to remove dampness.
The Radix Astragali, invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, Spontaneous perspiration, frequent fetal movement.
Rhizoma Sparganii, cures mainly spitting of blood, spits blood, and epistaxis is had blood in stool, and metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling down swells and ache.
Scolopendra, has activating QI to eliminate phlegm, preventing or arresting vomiting relieving distension, the liver soothing and the spleen invigorating, the multiple medicinal function of stomach function regulating.
Vine of Flos Lonicerae, has regulating qi-flowing for strengthening spleen, in tune, and dampness, reduce phlegm.Cure mainly the distension and fullness in the abdomen of stagnation of QI in spleen and stomach or pain, digestion not Good.Abdominal distention uncomfortable in chest in turbid damp resistance, indigestion and loss of appetite loose stool, the cough and asthma of phlegm-damp heap soil or fertilizer over and around the roots lung.
Semen Sterculiae Lychnophorae, dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, weight after dysentery, Proctoptosis, uterine prolapse.
The present invention uses above technical scheme, compared with prior art, has the advantage that the pharmaceutical composition tool benefit of the present invention Effect that gas nourishes blood, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing are anticancer, it is possible to effectively treat rectal cancer, strengthens patient's appetite, and enhancing is exempted from Epidemic disease power.
The most directly close detailed description of the invention technical scheme is described further.
[detailed description of the invention]
Embodiment 1
A kind of Chinese medicine formula treating rectal cancer, is made up of (every part of 1g) according to weight classification following components:
Radix Rehmanniae 10 parts, 10 parts of Radixs Astragali of Agkistrodon 10 parts, three210 parts of rib, 5 parts of vine of Flos Lonicerae of Scolopendra 4 parts, Semen Sterculiae Lychnophorae 5 Part.
After above weight classification composition, adding water 4-5 times by gross weight, warm fire decocts 2-3 hour, merges after decocting twice Decocting liquid, filters, adds adjuvant, make oral liquid.
Embodiment 2
A kind of Chinese medicine formula treating rectal cancer, is made up of (every part of 1g) according to weight classification following components:
Radix Rehmanniae 15 parts, Agkistrodon 15 parts, the Radix Astragali 15 parts, Rhizoma Sparganii 12 parts, Scolopendra 10 parts, vine of Flos Lonicerae 6 parts, fat greatly 10 parts of sea.
After above weight classification composition, adding water 4-5 times by gross weight, warm fire decocts 2-3 hour, merges after decocting twice Decocting liquid, filters, is concentrated into the paste that relative density is 1.32-1.40, then dry, pulverize into fine powder below 80 degree, adds Adjuvant (starch oar 10%, dextrin 10%, lactose 5%, dry starch 5%, stearic acid 2%, mannitol 1%, Talcum acid 2%), Mixing, makes capsule.
Embodiment 3
A kind of Chinese medicine formula treating rectal cancer, is made up of (every part of 1g) according to weight classification following components:
Radix Rehmanniae 20 parts, Agkistrodon 20 parts, the Radix Astragali 20 parts, Rhizoma Sparganii 14 parts, Scolopendra 15 parts, vine of Flos Lonicerae 8 parts, fat greatly 15 parts of sea.
After above weight classification composition, adding water 4-5 times by gross weight, warm fire decocts 2-3 hour, merges after decocting twice Decocting liquid, filters, is concentrated into the paste that relative density is 1.32-1.40, then dry, pulverize into fine powder below 80 degree, adds Adjuvant (starch oar 10%, dextrin 10%, lactose 5%, dry starch 5%, stearic acid 2%, magnesium stearate 1%, Talcum acid 2%), Mixing, makes granule.
Three above embodiment gained medicine is used for rectal cancer clinical trial, and use efficacy assessment standard is:
1, effective: body constitution strengthens, limbs are strong, and digestion and defecation etc. are uncomfortable substantially to be alleviated, and CT examination rectum region tumors tumor body contracts Little, other position does not finds nascent tumor.
2, effective: body constitution strengthens, digestion and the discomfort such as defecation have alleviation, CT examination rectal neoplasm tumor body to have no increase, other position Have no nascent tumor.
3, deteriorate: disease is unchanged, and rectal neoplasm tumor body has increased, or other position finds nascent tumor.
The 80 example rectal cancer patients that in February, 2012 in March, 2014 seeks medical advice, male 43 examples, female 37 example, age 20-85 year, The course of disease 3 months to 3 years.
This test is provided with 3 test group altogether, and each test group random assortment patient treats.Test group 1 uses example 1 gained Drug therapy, test group 2 uses the Drug therapy of embodiment 2 gained, test group 3 to use the medicine of embodiment 3 gained Thing is treated, if 20 examples are matched group, matched group uses western medicine treatment, and total effective rate is 50%.
Obtained straight fruit is such as following table:
Test group Number of cases Effectively Effective Deteriorate Effective percentage (%)
Test group 1 20 17 2 1 85%
Test group 2 20 16 4 0 80%
Test group 3 20 17 4 0 85%
Matched group 20 10 6 4 50%
From data above analysis, it can be deduced that the medicine of gained of the present invention treatment rectal cancer, total effective rate reaches more than 80%, peace The most reliably, having no side effect, and embodiment 3 is preferred plan, effective percentage can reach 85%.
Although for reaching illustration purpose, the above is the preferred embodiments of the present invention, is not limited to the present invention, to the greatest extent The present invention has been described in detail by pipe with reference to previous embodiment, and for a person skilled in the art, it still can be right The technical scheme that foregoing embodiments is recorded is modified, or wherein portion of techniques feature is carried out equivalent.All at this Within bright spirit and principle, any modification, equivalent substitution and improvement etc. made, should be included in protection scope of the present invention Within.

Claims (10)

1. the Chinese medicine formula treating rectal cancer, it is characterised in that the active ingredient of described pharmaceutical composition is by following raw material system For forming: Radix Rehmanniae, Agkistrodon, the Radix Astragali, Rhizoma Sparganii, Scolopendra, vine of Flos Lonicerae, Semen Sterculiae Lychnophorae.
2. the Chinese medicine formula treating rectal cancer, it is characterised in that the active ingredient of described pharmaceutical composition is by following weight portion Raw material be prepared from: Radix Rehmanniae 10 parts-20 parts, Agkistrodon 10 parts-20 parts, the Radix Astragali 10 parts-20 parts, Rhizoma Sparganii 10 part-14 Part, Scolopendra 5 parts-15 parts, vine of Flos Lonicerae 4 parts-8 parts, Semen Sterculiae Lychnophorae 5 parts-15 parts.
3. treat the Chinese medicine formula of rectal cancer as claimed in claim 1, it is characterised in that the active ingredient of described pharmaceutical composition It is prepared from by the raw material of following weight portion: Radix Rehmanniae 10 parts, Agkistrodon 10 parts, the Radix Astragali 10 parts, Rhizoma Sparganii 10 parts, Scolopendra 5 parts, vine of Flos Lonicerae 4 parts, Semen Sterculiae Lychnophorae 5 parts.
4. treat the Chinese medicine formula of rectal cancer as claimed in claim 1, it is characterised in that the active ingredient of described pharmaceutical composition It is prepared from by the raw material of following weight portion: Radix Rehmanniae 15 parts, Agkistrodon 15 parts, the Radix Astragali 15 parts, Rhizoma Sparganii 12 parts, Scolopendra 10 parts, vine of Flos Lonicerae 6 parts, Semen Sterculiae Lychnophorae 10 parts.
5. the Chinese medicine formula treating rectal cancer, it is characterised in that the active ingredient of described pharmaceutical composition is by following weight portion Raw material be prepared from: Radix Rehmanniae 20 parts, Agkistrodon 20 parts, the Radix Astragali 20 parts, Rhizoma Sparganii 14 parts, Scolopendra 15 parts, Flos Lonicerae 8 parts of rattan, Semen Sterculiae Lychnophorae 15 parts.
6. the Chinese medicine formula treating rectal cancer as claimed in claim 1, it is characterised in that the dosage form of described pharmaceutical composition For oral liquid, granule, capsule or tablet.
7. the as claimed in claim 1 Chinese medicine formula treating rectal cancer, it is characterised in that take by weight ratio Radix Rehmanniae, Agkistrodon, the Radix Astragali, Rhizoma Sparganii, Scolopendra, vine of Flos Lonicerae and Semen Sterculiae Lychnophorae, add water 4-5 times by gross weight, and warm fire decocts 2-3 hour, Collecting decoction after decocting twice, filters, makes oral liquid.
8. the as claimed in claim 1 Chinese medicine formula treating rectal cancer, it is characterised in that take by weight ratio Radix Rehmanniae, Agkistrodon, the Radix Astragali, Rhizoma Sparganii, Scolopendra, vine of Flos Lonicerae and Semen Sterculiae Lychnophorae, add water 4-5 times by gross weight, and warm fire decocts 2-3 hour, Collecting decoction after decocting twice, filters, and is concentrated into the paste that relative density is 1.32-1.40, then is dried below 80 degree, powder It is broken into fine powder, adds adjuvant, mixing, make granule.
9. the as claimed in claim 1 Chinese medicine formula treating rectal cancer, it is characterised in that take by weight ratio Radix Rehmanniae, Agkistrodon, the Radix Astragali, Rhizoma Sparganii, Scolopendra, vine of Flos Lonicerae and Semen Sterculiae Lychnophorae, add water 4-5 times by gross weight, and warm fire decocts 2-3 hour, Collecting decoction after decocting twice, filters, and is concentrated into the paste that relative density is 1.32-1.40, then is dried below 80 degree, powder It is broken into fine powder, adds adjuvant, mixing, make tablet.
The Chinese medicine formula for the treatment of rectal cancer the most as claimed in claim 1 or 2 or 3 or 4, it is characterised in that by weight Proportioning takes Radix Rehmanniae, Agkistrodon, the Radix Astragali, Rhizoma Sparganii, Scolopendra, vine of Flos Lonicerae and Semen Sterculiae Lychnophorae, adds water 4-5 times by gross weight, temperature Fire decocts 2-3 hour, collecting decoction after decocting twice, filtration, is concentrated into the paste that relative density is 1.32-1.40, then Less than 80 degree dry, pulverize into fine powder, add adjuvant, mixing, make capsule.
CN201510169680.4A 2015-04-13 2015-04-13 A kind of Chinese medicine formula treating rectal cancer Pending CN106138922A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106619870A (en) * 2016-12-26 2017-05-10 成都菱祐生物科技有限公司 Composition for treating digestive system neoplasms, and preparation method of composition

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104069294A (en) * 2014-03-28 2014-10-01 上海远东中医药研究所 Anti-cancer Chinese patent medicine preparation and extraction and compatibility process thereof
CN104324091A (en) * 2014-11-11 2015-02-04 蒋丽红 Traditional Chinese medicine formula for treating rectal cancer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104069294A (en) * 2014-03-28 2014-10-01 上海远东中医药研究所 Anti-cancer Chinese patent medicine preparation and extraction and compatibility process thereof
CN104324091A (en) * 2014-11-11 2015-02-04 蒋丽红 Traditional Chinese medicine formula for treating rectal cancer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
叶晔等: "吴良村治疗肠癌经验撷菁", 《中华中医药学刊》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106619870A (en) * 2016-12-26 2017-05-10 成都菱祐生物科技有限公司 Composition for treating digestive system neoplasms, and preparation method of composition
CN106619870B (en) * 2016-12-26 2020-07-14 成都菱祐生物科技有限公司 Composition for treating digestive system tumor and preparation method thereof

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Application publication date: 20161123

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