CN104288631A - Medicine composition for treating colon cancer and preparation method thereof - Google Patents

Medicine composition for treating colon cancer and preparation method thereof Download PDF

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CN104288631A
CN104288631A CN201410628447.3A CN201410628447A CN104288631A CN 104288631 A CN104288631 A CN 104288631A CN 201410628447 A CN201410628447 A CN 201410628447A CN 104288631 A CN104288631 A CN 104288631A
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parts
pharmaceutical composition
colon cancer
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treatment
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黄自宇
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/902Sparganiaceae (Bur-reed family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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Abstract

The invention relates to a medicine composition for treating colon cancer and a preparation method thereof, and belongs to technologies of traditional Chinese medicines. The medicine composition with a good efficacy is prepared from the following components in parts by weight: 10-20 parts of rhizoma sparganii, 10-20 parts of long-noded pit viper, 10-20 parts of atractylodes macrocephala koidz, 10-14 parts of pseudo-ginseng, 5-15 parts of fingered citron,4-8 parts of purslane, and 5-15 parts of fructus aurantii. The medicine composition disclosed by the invention has the efficacies of benefiting qi, nourishing blood, promoting blood circulation for removing blood stasis, clearing heat, removing toxicity and resisting cancers, and through the medicine composition, the colon cancer can be effectively treated, the appetite of a patient is enhanced, and the immunity is enhanced.

Description

A kind of pharmaceutical composition for the treatment of colon cancer and preparation method thereof
[technical field]
The present invention relates to technical field of Chinese medicine, particularly a kind of pharmaceutical composition for the treatment of colon cancer and preparation method thereof.
[technical background]
At present in the field of Chinese medicines for the treatment of colon cancer, there is the weak point of two aspects: one is that therapeutic effect is obvious not, two be take effect slower.So that large quantities of colorectal cancer patients or can not with the growth for the treatment of Chinese medicine Tumor suppression, or tumor recurrence, transfer, diffusion after excision, patient and family members thereof are unsatisfied with this.
For problem set forth above, the invention provides a kind of Chinese medicine for the treatment of colon cancer, it can effectively solve in the past in treatment of colon cancer effect obvious not, take effect slower problem, the present invention is effective, instant effect, has the advantage of Be very effective, determined curative effect.
[summary of the invention]
The object of the present invention is to provide a kind of can pharmaceutical composition for the treatment of colon cancer and preparation method thereof effectively, provided by the present invention be pharmaceutical composition for the treatment of colon cancer and preparation method thereof can invigorating the spleen and benefiting QI, YIN nourishing is logical falls.Colon cancer can be treated preferably, have no side effect, safe and reliable.
Technical scheme of the present invention is as follows:
A kind of pharmaceutical composition for the treatment of colon cancer and preparation method thereof, is characterized in that: the active ingredient of described pharmaceutical composition is prepared from by following raw material: Rhizoma Sparganii, Agkistrodon, the Rhizoma Atractylodis Macrocephalae, Radix Notoginseng, Fructus Citri Sarcodactylis, Herba Portulacae, Fructus Aurantii.
Further, the active ingredient of preferred described pharmaceutical composition is prepared from by the raw material of following weight portion: Rhizoma Sparganii 10 parts-20 parts, Agkistrodon 10 parts-20 parts, the Rhizoma Atractylodis Macrocephalae 10 parts-20 parts, Radix Notoginseng 10 parts-14 parts, Fructus Citri Sarcodactylis 5 parts-15 parts, Herba Portulacae 4 parts-8 parts, Fructus Aurantii 5 parts-15 parts.
Further, the active ingredient of preferred described pharmaceutical composition is prepared from+Rhizoma Sparganii 15 parts, Agkistrodon 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Notoginseng 12 parts, Fructus Citri Sarcodactylis 10 parts, Herba Portulacae 6 parts, Fructus Aurantii 10 parts by the raw material of following weight portion.
The dosage form of above-mentioned arbitrary pharmaceutical composition is preferably oral liquid, granule, capsule or tablet.
The preparation method of above-mentioned arbitrary pharmaceutical composition, is characterized in that, gets Rhizoma Sparganii, Agkistrodon, the Rhizoma Atractylodis Macrocephalae, Radix Notoginseng, Fructus Citri Sarcodactylis, Herba Portulacae and Fructus Aurantii by weight ratio, add water 4-5 doubly by gross weight, and temperature fire decocts 2-3 hour, collecting decoction after decocting twice, filter, make oral liquid.
The preparation method of above-mentioned arbitrary pharmaceutical composition, is characterized in that, gets Rhizoma Sparganii, Agkistrodon, the Rhizoma Atractylodis Macrocephalae, Radix Notoginseng, Fructus Citri Sarcodactylis, Herba Portulacae and Fructus Aurantii by weight ratio, adds water 4-5 doubly by gross weight, and temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters; Be concentrated into the paste that relative density is 1.32-1.40, then dry, pulverize into fine powder below 80 degree, add adjuvant, mixing, makes granule.
The preparation method of above-mentioned arbitrary pharmaceutical composition, is characterized in that, gets Rhizoma Sparganii, Agkistrodon, the Rhizoma Atractylodis Macrocephalae, Radix Notoginseng, Fructus Citri Sarcodactylis, Herba Portulacae and Fructus Aurantii by weight ratio, adds water 4-5 doubly by gross weight, and temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters; Be concentrated into the paste that relative density is 1.32-1.40, then dry, pulverize into fine powder below 80 degree, add adjuvant, mixing, makes tablet.
The raw material of Chinese medicine medicine details adopted in the present invention is as follows:
Rhizoma Sparganii, removing blood stasis, circulation of qi promoting, removing food stagnancy, pain relieving.Zhi lumps in the chest and abdomen, coagulation of QI-blood, trusted subordinate's pain, the lower swollen pain of the side of body, amenorrhea, postnatal blood stasis is suffered from abdominal pain, and traumatic injury, skin ulcer swells hard.
Agkistrodon, sweet in the mouth, cold in nature.Return stomach, lung, large intestine, urinary bladder channel, heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, promoting urination to remove dampness.
The Rhizoma Atractylodis Macrocephalae, invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Radix Notoginseng, cures mainly spitting of blood, and spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, and breast ventral spine pain, tumbling down swells and ache.
Fructus Citri Sarcodactylis, has activating QI to eliminate phlegm, preventing or arresting vomiting relieving distension, the liver soothing and the spleen invigorating, the multiple medicinal function of stomach function regulating.
Herba Portulacae, has regulating qi-flowing for strengthening spleen, and in tune, dampness, reduces phlegm.Cure mainly distension and fullness in the abdomen or pain, the dyspepsia of stagnation of QI in spleen and stomach.The cough and asthma of the abdominal distention uncomfortable in chest in turbid damp resistance, indigestion and loss of appetite loose stool, phlegm-damp heap soil or fertilizer over and around the roots lung.
Fructus Aurantii, dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.
The present invention adopts above technical scheme, compared with prior art, has the following advantages: effect that pharmaceutical composition tool benefiting QI and nourishing blood of the present invention, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing are anticancer, effectively can treat colon cancer, strengthens patient's appetite, enhancing immunity.
Below in conjunction with detailed description of the invention, technical scheme of the present invention is described further.
[detailed description of the invention]
Embodiment 1
A kind of pharmaceutical composition for the treatment of colon cancer and preparation method thereof, is made up of (every part of 1g) according to weight classification following component: Rhizoma Sparganii 10 parts, Agkistrodon 10 parts of Rhizoma Atractylodis Macrocephalaes 10 parts, Radix Notoginseng 10 parts, Fructus Citri Sarcodactylis 5 portions of Herba Portulacaes 4 parts, Fructus Aurantii 5 parts.
After above weight classification composition, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters, adds adjuvant, make oral liquid.
Embodiment 2
A kind of pharmaceutical composition for the treatment of colon cancer and preparation method thereof, is made up of (every part of 1g) according to weight classification following component: Rhizoma Sparganii 15 parts, Agkistrodon 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Notoginseng 12 parts, Fructus Citri Sarcodactylis 10 parts, Herba Portulacae 6 parts, Fructus Aurantii 10 parts.
After above weight classification composition, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters, be concentrated into the paste that relative density is 1.32-1.40, below 80 degree, dry, pulverize into fine powder again, add adjuvant (starch oar 10%, dextrin 10%, lactose 5%, dry starch 5%, stearic acid 2%, mannitol 1%, Talcum acid 2%), mixing, makes capsule.
Embodiment 3
A kind of pharmaceutical composition for the treatment of colon cancer and preparation method thereof, is made up of (every part of 1g) according to weight classification following component: Rhizoma Sparganii 20 parts, Agkistrodon 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Radix Notoginseng 14 parts, Fructus Citri Sarcodactylis 15 parts, Herba Portulacae 8 parts, Fructus Aurantii 15 parts.
After above weight classification composition, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters, be concentrated into the paste that relative density is 1.32-1.40, below 80 degree, dry, pulverize into fine powder again, add adjuvant (starch oar 10%, dextrin 10%, lactose 5%, dry starch 5%, stearic acid 2%, magnesium stearate 1%, Talcum acid 2%), mixing, makes granule.
Above three embodiment gained medicines are used for colorectal cancer clinical test, use efficacy assessment standard is:
1, effective: body constitution strengthens, limbs are strong, and digestion and defecation etc. are uncomfortable obviously to be alleviated, and CT examination colon site tumor tumor body reduces, and other position does not find nascent tumor.
2, effective: body constitution strengthens, the discomforts such as digestion and defecation have alleviation, and CT examination colon tumor tumor body has no increase, and other position has no nascent tumor.
3, worsen: disease is unchanged, and colon tumor tumor body increases to some extent, or other position finds nascent tumor.
The 80 routine colorectal cancer patients that year March in February, 2012 to 2014 seeks medical advice, man 43 example, female 37 example, age 20-85 year, the course of disease 3 months to 3 years.
This test is provided with 3 test group altogether, and each test group random assortment patient treats.Test group 1 use-case 1 gained Drug therapy, test group 2 uses the Drug therapy of embodiment 2 gained, and test group 3 uses the Drug therapy of embodiment 3 gained, if 20 examples are matched group, matched group adopts western medicine treatment, and total effective rate is 50%.
The result obtained is as following table:
Test group Number of cases Effectively Effective Worsen Effective percentage (%)
Test group 1 20 17 2 1 85%
Test group 2 20 16 4 0 80%
Test group 3 20 17 4 0 85%
Matched group 20 10 6 4 50%
From above data analysis, can draw the medicine of gained of the present invention treatment colon cancer, total effective rate reaches more than 80%, safe and reliable, have no side effect, and embodiment 3 is preferred plan, and effective percentage can reach 85%.
Although for reaching illustration purpose, the above is the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme that foregoing embodiments is recorded, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. pharmaceutical composition for the treatment of colon cancer and preparation method thereof, is characterized in that, the active ingredient of described pharmaceutical composition is prepared from by following raw material: Rhizoma Sparganii, Agkistrodon, the Rhizoma Atractylodis Macrocephalae, Radix Notoginseng, Fructus Citri Sarcodactylis, Herba Portulacae, Fructus Aurantii.
2. pharmaceutical composition for the treatment of colon cancer and preparation method thereof, it is characterized in that, the active ingredient of described pharmaceutical composition is prepared from by the raw material of following weight portion: Rhizoma Sparganii 10 parts-20 parts, Agkistrodon 10 parts-20 parts, the Rhizoma Atractylodis Macrocephalae 10 parts-20 parts, Radix Notoginseng 10 parts-14 parts, Fructus Citri Sarcodactylis 5 parts-15 parts, Herba Portulacae 4 parts-8 parts, Fructus Aurantii 5 parts-15 parts.
3. pharmaceutical composition for the treatment of colon cancer and preparation method thereof as claimed in claim 1, it is characterized in that, the active ingredient of described pharmaceutical composition is prepared from by the raw material of following weight portion: Rhizoma Sparganii 10 parts, Agkistrodon 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Notoginseng 10 parts, Fructus Citri Sarcodactylis 5 parts, Herba Portulacae 4 parts, Fructus Aurantii 5 parts.
4. pharmaceutical composition for the treatment of colon cancer and preparation method thereof as claimed in claim 1, it is characterized in that, the active ingredient of described pharmaceutical composition is prepared from by the raw material of following weight portion: Rhizoma Sparganii 15 parts, Agkistrodon 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Notoginseng 12 parts, Fructus Citri Sarcodactylis 10 parts, Herba Portulacae 6 parts, Fructus Aurantii 10 parts.
5. pharmaceutical composition for the treatment of colon cancer and preparation method thereof, it is characterized in that, the active ingredient of described pharmaceutical composition is prepared from by the raw material of following weight portion: Rhizoma Sparganii 20 parts, Agkistrodon 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Radix Notoginseng 14 parts, Fructus Citri Sarcodactylis 15 parts, Herba Portulacae 8 parts, Fructus Aurantii 15 parts.
6. pharmaceutical composition for the treatment of colon cancer as claimed in claim 1 and preparation method thereof, it is characterized in that, the dosage form of described pharmaceutical composition is oral liquid, granule, capsule or tablet.
7. pharmaceutical composition for the treatment of colon cancer as claimed in claim 1 and preparation method thereof, it is characterized in that, get Rhizoma Sparganii, Agkistrodon, the Rhizoma Atractylodis Macrocephalae, Radix Notoginseng, Fructus Citri Sarcodactylis, Herba Portulacae and Fructus Aurantii by weight ratio, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, collecting decoction after decocting twice, filters, makes oral liquid.
8. pharmaceutical composition for the treatment of colon cancer as claimed in claim 1 and preparation method thereof, is characterized in that, get Rhizoma Sparganii, Agkistrodon, the Rhizoma Atractylodis Macrocephalae, Radix Notoginseng, Fructus Citri Sarcodactylis, Herba Portulacae and Fructus Aurantii by weight ratio, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters, be concentrated into the paste that relative density is 1.32-1.40, below 80 degree, dry, pulverize into fine powder again, add adjuvant, mixing, makes granule.
9. pharmaceutical composition for the treatment of colon cancer as claimed in claim 1 and preparation method thereof, is characterized in that, get Rhizoma Sparganii, Agkistrodon, the Rhizoma Atractylodis Macrocephalae, Radix Notoginseng, Fructus Citri Sarcodactylis, Herba Portulacae and Fructus Aurantii by weight ratio, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters, be concentrated into the paste that relative density is 1.32-1.40, below 80 degree, dry, pulverize into fine powder again, add adjuvant, mixing, makes tablet.
10. the pharmaceutical composition and preparation method thereof for the treatment of colon cancer as claimed in claim 1 or 2 or 3 or 4, is characterized in that, get Rhizoma Sparganii, Agkistrodon, the Rhizoma Atractylodis Macrocephalae, Radix Notoginseng, Fructus Citri Sarcodactylis, Herba Portulacae and Fructus Aurantii by weight ratio, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters, be concentrated into the paste that relative density is 1.32-1.40, below 80 degree, dry, pulverize into fine powder again, add adjuvant, mixing, makes capsule.
CN201410628447.3A 2014-11-11 2014-11-11 Medicine composition for treating colon cancer and preparation method thereof Pending CN104288631A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105055787A (en) * 2015-09-18 2015-11-18 刘大仟 Capsule for treating colon cancers and preparation method thereof
CN105213571A (en) * 2015-10-22 2016-01-06 丘勇番 A kind of Chinese medicine for the treatment of colon cancer and preparation method thereof
CN105232578A (en) * 2015-10-30 2016-01-13 曹乃月 Anti-colon-cancer medicine composition containing mitomycin
CN106138554A (en) * 2015-04-13 2016-11-23 张金桃 A kind of Chinese medicine treating colon cancer and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101537146A (en) * 2008-03-19 2009-09-23 北京绿源求证科技发展有限责任公司 Chinese medicine for treating carcinoma of colon

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101537146A (en) * 2008-03-19 2009-09-23 北京绿源求证科技发展有限责任公司 Chinese medicine for treating carcinoma of colon

Non-Patent Citations (3)

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Title
刘一等: "《新编家庭医生手册》", 28 February 2002 *
吴和木等: "扶正消瘤汤配合白细胞介素Ⅱ治疗结肠癌60例观察", 《中国中医药科技》 *
黄智芬 等: "健脾化瘀汤配合化疗治疗晚期大肠癌34例临床观察", 《中国中医药科技》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106138554A (en) * 2015-04-13 2016-11-23 张金桃 A kind of Chinese medicine treating colon cancer and preparation method thereof
CN105055787A (en) * 2015-09-18 2015-11-18 刘大仟 Capsule for treating colon cancers and preparation method thereof
CN105213571A (en) * 2015-10-22 2016-01-06 丘勇番 A kind of Chinese medicine for the treatment of colon cancer and preparation method thereof
CN105232578A (en) * 2015-10-30 2016-01-13 曹乃月 Anti-colon-cancer medicine composition containing mitomycin

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Application publication date: 20150121