CN104147452A - Medicine for treating mid-late stage liver cancer - Google Patents

Abstract

A medicine for treating the mid-late stage liver cancer comprises 6.7-20.4wt% of Radix Astragali, 2.1-5.6wt% of radix bupleuri, 3.2-10.8wt% of white peony root, 2.1-5.6wt% of Atractylodes lancea, 2.1-5.6wt% of Rhizoma Atractylodis Macrocephalae, 3.2-10.8wt% of Polyporus Umbellatus, 3.2-10.8wt% of Poria cocos, 6.7-20.4wt% of Barbed Skullcap Herb, 2.1-5.6wt% of Rhizoma Cyperi, 3.2-10.8wt% of coix seed, 3.2-10.8wt% of Capillary Wormwood Herb, 2.1-5.6wt% of Salvia miltiorrhiza slice, 0.6-1.9wt% of pangolin, 3.2-10.8wt% of Herba Lycopi, 3.2-10.8wt% of Rhizoma Alismatis, 2.1-5.6wt% of gizzard-membrane, 6.7-16.2wt% of Charred Triplet and 1.2-2.3wt% of licorice root. The medicine has the efficacies of qi tonifying, spleen invigorating, liver coursing, stomach harmonizing, stasis dissolving, detoxifying, hardness softening and bind dissipating, has the advantages of simple preparation, taking convenience, no toxic side effects and low price, and is especially suitable for mid-late stage liver cancer chemotherapy embolism.

Description

The medicine for the treatment of mid and late liver cancer

technical field:

The present invention relates to a kind of medicine for the treatment of cancer, particularly one carries out to mid and late liver cancer patient the Chinese herbal medicine of taking for 3 days-2 weeks after hepatic arterial chemoembolization.

background technology:

Hepatocarcinoma is a kind of modal malignant tumor in digestive system, sickness rate ascendant trend is obvious in the recent period, in treatment, mostly adopt hands art, get involved, expectant treatment, along with social development, interventional therapy becomes people's first-selection, a kind of Wicresoft mainly due to interventional therapy, safe hands art, the degree that human body is hurt is less, but, interventional therapy is repeatedly larger to patient's liver function injury, the financial burden of patient's spirit and quality of life and family has great impact, at present, after the patient of implementation interventional therapy, can only treat by Western medicine, particularly postoperative 3 days-2 weeks, can make the empty healthy energy of patient more empty, anticancer power further declines, for the relapse and metastasis of remaining cancer poison provides advantage, the cost of Western medicine is higher, patient's burden is heavier, simultaneously, Western medicine has certain side effect, long-term taking, can also produce certain untoward reaction, now, China does not also have one to utilize Chinese herbal medicine to carry out carrying out hepatoprotective after hepatic arterial chemoembolization to mid and late liver cancer patient.

invention task:

Object of the present invention is exactly a kind of liver function-protecting to patient will be provided, heighten the effect of a treatment, improve quality of life, extend patients ' lives, alleviate the medicine of the treatment mid and late liver cancer of household economy burden.

The object of the present invention is achieved like this: a kind of medicine for the treatment of mid and late liver cancer, it is characterized in that it comprises that following raw material is by weight forming: the Radix Astragali 6.7-20.4%, Radix Bupleuri 2.1-5.6%, the Radix Paeoniae Alba 3.2-10.8%, Rhizoma Atractylodis 2.1-5.6%, the Rhizoma Atractylodis Macrocephalae 2.1-5.6%, Polyporus 3.2-10.8%, Poria 3.2-10.8%, Herba Scutellariae Barbatae 6.7-20.4%, Rhizoma Cyperi 2.1-5.6%, thatch rice 3.2-10.8%, Herba Artemisiae Scopariae 3.2-10.8%, Radix Salviae Miltiorrhizae Tabellae 2.1-5.6%, Squama Manis 0.6-1.9%, Herba Lycopi 3.2-10.8%, Rhizoma Alismatis 3.2-10.8%, Endothelium corneum 2.1-5.6%, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) each 6.7-16.2%, Radix Glycyrrhizae 1.2-2.3%.

The medicine for the treatment of mid and late liver cancer of the present invention, it comprises following raw material by weight: the Radix Astragali 10.1-15.2%, Radix Bupleuri 2.2-5.2%, the Radix Paeoniae Alba 4.5-6.6%, Rhizoma Atractylodis 2.2-5.2%, the Rhizoma Atractylodis Macrocephalae 2.2-5.2%, Polyporus 4.5-6.6%, Poria 4.5-6.6%, Herba Scutellariae Barbatae 10.1-15.2%, Rhizoma Cyperi 2.2-5.2%, thatch rice 4.5-6.6%, Herba Artemisiae Scopariae 4.5-6.6%, Radix Salviae Miltiorrhizae Tabellae 2.2-5.2%, Squama Manis 0.7-1.6%, Herba Lycopi 4.5-6.6%, Rhizoma Alismatis 4.5-6.6%, Endothelium corneum 2.2-5.2%, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) are each 9.1-15.6%, Radix Glycyrrhizae 1.2-2.3%.

The medicine for the treatment of mid and late liver cancer of the present invention, it also comprises following raw material by weight: the Radix Rehmanniae 4.5-6.6%, Radix Cynanchi Atrati 3.1-5.7%.

The medicine for the treatment of mid and late liver cancer of the present invention, it also comprises following raw material by weight: Rhizoma Corydalis 4.5-6.6%, Radix Curcumae 2.2-5.2%, Lignum Sappan 2.2-5.2%.

The medicine for the treatment of mid and late liver cancer of the present invention, it also comprises following raw material by weight: Radix Et Rhizoma Rhei 1.2-3.8%.

The medicine for the treatment of mid and late liver cancer of the present invention, it also comprises following raw material by weight: Radix Notoginseng powder 1.2-3.8%.

The medicine for the treatment of mid and late liver cancer of the present invention, it also comprises following raw material by weight: Radix Trichosanthis 4.5-6.6%.

Medicine after treatment Transcatheter Arterial Chemoembolization On Advanced Hepatocellular Carcinoma of the present invention, to be made as decoction as main, also can be made and be pill, capsule, medicamental pulverata electuary.

Hepatocarcinoma is mainly supplied overall tumor body by the tumor vasa vasorum of Branch of hepatic artery, in the active tumor neighboring area of growth of tumour cell, exist many branch of portal vein simultaneously, in the time there is tumor in liver, its tumor feeding can obtain blood from contiguous tremulous pulse by ramus anastomoticus and supply, the blood supply of hepatocarcinoma more than 90%-95% from Hepatic artery, therefore by hepatic artery catheterization administration, can make medicine directly enter liver cancer tissue, greatly improve local drug level, cell is is farthest killed and wounded, after intervention, carry out partner treatment by Chinese herbal medicine, play the effect of attenuation synergistic, can avoid nauseating, vomiting, degradation digestive tract side effects under appetite, can alleviate the caused bone marrow depression reaction of chemotherapy, can avoid the leukocyte that may occur, platelet decline phenomenon, strengthen the protection to liver function, avoid getting involved that medicine directly acts on liver and the infringement of the liver function that causes, because Chinese herbal medicine has the effect of the tumor of killing, tumor suppression, thereby, can kill to greatest extent cancer poison, reduce the recurrence probability of cancer poison, use Chinese medicine to change cancerous cell characteristic, thereby play the effect that suppresses neoplasm metastasis.

the Radix Astragali: sweet in the mouth, feeble QI temperature, gas is thin and taste is dense, can rise to fall, and the yang aspect of yang is also, nontoxic, specially QI invigorating.The warp lunar, the few the moon of lunar, the hands of foot of starting with, invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema Radix Astragali disk, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes; The present invention is mainly used in healthy energy blood stasis dispelling poison;

radix Bupleuri:nature and flavor: bitter flat, Gui Jing, enter liver, gallbladder meridian, function: deliver, bring down a fever, soothing the liver, resolving depression, yang invigorating, cure mainly cat fever, alternate attack of chill and fever, malaria, side of body distending pain, menoxenia, treating SHAO YANG disease by mediation, soothing liver-QI stomach function regulating, ascending up spleen-Qi and Yang.Control alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste deafness, headache and dizziness, malaria, diarrhea proctoptosis, menoxenia, uterine prolapse, invasion of the blood-chamber by heat; The present invention is mainly used in soothing the liver easing the affected liver;

the Radix Paeoniae Alba:nature and flavor picric acid, cool, nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia; The present invention is mainly used in soothing the liver easing the affected liver;

rhizoma Atractylodis:meridian distribution of property and flavor is pungent, bitter, temperature.Return spleen, stomach, Liver Channel, drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, the edema of having loose bowels, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia; The present invention is mainly used in removing dampness and lets out turbid;

the Rhizoma Atractylodis Macrocephalae:bitter, sweet, temperature, returns spleen, stomach warp, invigorating the spleen and benefiting QI, and dampness diuretic, hidroschesis, antiabortive,

For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement; The present invention is mainly used in spleen invigorating;

polyporus:property is put down, sweet in the mouth, and promoting diuresis to eliminate damp pathogen, cures mainly dysuria, drenches the diseases such as drop burning pain, edema, and has antitumaous effect; The present invention is mainly used in removing dampness and lets out turbid;

poria:sweet in the mouth, light, property are flat, be used as medicine there is promoting diuresis to eliminate damp pathogen, the function of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming, modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect; The present invention is mainly used in spleen invigorating;

herba Scutellariae Barbatae:pungent, bitter, cold.Return lung, liver, kidney channel, function with cure mainly: heat-clearing and toxic substances removing, blood stasis dispelling diuresis.For furuncle swelling toxin, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, edema, jaundice; The present invention is mainly used in the heat clearing away of detoxifying;

rhizoma Cyperi:the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, menoxenia, amenorrhea dysmenorrhea, colic of cold type stomachache, distending pain of the breast; The present invention is mainly used in soothing the liver easing the affected liver;

semen Coicis:nature and flavor are cool in nature, sweet in the mouth, light, and spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, can be used for treating edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen; The present invention is mainly used in spleen invigorating;

herba Artemisiae Scopariae:bitter, pungent, be slightly cold, return spleen, stomach, liver, gallbladder meridian, clearing away damp-heat, jaundice eliminating subcutaneous ulcer, for Huang

Subcutaneous ulcer oliguria, eczema pruritus, infectious jaundice type hepatitis ,. pharmaceutical research has function of gallbladder promoting, liver function protecting,

Antipyretic, antiinflammatory, blood fat reducing, blood pressure lowering, the effects such as coronary dilating; The present invention is mainly used in the heat clearing away of detoxifying;

radix Salviae Miltiorrhizae Tabellae:bitter in the mouth, micro-pungent, cold nature; The medicine of the heart, spleen, liver, kidney blood system; There is blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind, effect of removing heat from blood detumescence; Cure mainly blood stasis head, breast, the side of body, abdomen pain, gather, menoxenia, dysmenorrhea amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, arthralgia, traumatic injury congestive edema, epidemic febrile disease is vexed, palpitation due to deficiency of blood, sore swollen toxin, red rash scabies; The present invention is mainly used in soothing the liver easing the affected liver;

squama Manis:salty, be slightly cold, return liver, stomach warp, the stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, expel wind to dredge collateral, for

Jing Bi WEIJIA, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture; The present invention is mainly used in softening the hard mass

Eliminating stagnation;

herba Lycopi:toil, tepor, enters liver, spleen channel, invigorates blood circulation, and row water, controls amenorrhea ， mass in the abdomen, the stagnant stomachache of the stasis of blood in puerperal, body and face edema, injury from falling down, incised wound, carbuncle; The present invention is mainly used in removing dampness and lets out turbid;

rhizoma Alismatis:sweet in the mouth, light, cold in nature, return kidney, urinary bladder channel, promoting diuresis to eliminate damp pathogen, expels the heat-evil treating stranguria, main little

Just unfavorable, the puckery pain of pyretic stranguria, edema distension, has loose bowels, dizziness due to fluid-retention, seminal emission; Being mainly used in of the present invention

Diarrhea due to damp pathogen is turbid;

endothelium corneum:sweet, flat, puckery, spleen channel, strengthening the spleen to promote digestion, arresting seminal emission, eliminating mass fossil, main dyspepsia, dysentery, infantile malnutrition, the seminal emission enuresis, urinary system calculus, cholelithiasis, lump in the abdomen amenorrhea; The present invention is mainly used in stomach function regulating and helps digestion;

jIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata):be Fructus Hordei Germinatus (parched to brown), Fructus Crataegi (parched to brown), Massa Medicata Fermentata (parched to brown), this three tastes medicine all has the stagnant function of good removing food stagnancyization, but has different separately features, and Fructus Hordei Germinatus (parched to brown) has the effect of good digestible starch group food; Fructus Crataegi (parched to brown) is good at treating meat or greasy dyspepsia due to too much; Massa Medicata Fermentata (parched to brown) is beneficial to digestion rice and flour food, and three medicines share, and can strengthen significantly digestive function; The present invention is mainly used in stomach function regulating and helps digestion;

radix Glycyrrhizae:invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong; The present invention is mainly used in spleen invigorating;

the Radix Rehmanniae:sweet in the mouth, hardship, cold in nature, energy YIN nourishing and the production of body fluid promoting, clearing away heat and cooling blood, Radix Rehmanniae clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis, for consumption of YIN caused by febrile disease, crimson tongue excessive thirst, sends out speckle dermexanthesis, spit blood, epistaxis, laryngopharynx swelling and pain.Radix Rehmanniae clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid, for calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis, sends out speckle dermexanthesis; The present invention is mainly used in the deficiency of YIN and moves back low grade fever;

radix Cynanchi Atrati:bitter in the mouth, salty, cold in nature, cure mainly warm, fever of the body macule, hectic fever hectic fever due to YIN-deficiency, cough due to lung-heat, puerperal fidgets due to deficiency, pyretic stranguria, stranguria with blood, laryngopharynx swelling and pain, sore and toxic, venom; The present invention is mainly used in the deficiency of YIN and moves back low grade fever;

rhizoma Corydalis:acrid in the mouth, hardship, warm in nature, there is promoting blood circulation to remove blood stasis, the function of promoting the circulation of QI pain relieving, for the each portion of whole body gas

Stagnant blood stasis is pain, dysmenorrhea, and amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain; Master of the present invention

Be used for hepatic region or the right shoulder pain qi depression to blood stasis of dispelling;

radix Curcumae:pungent, bitter, cold, return liver, the heart, lung meridian, regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice,

For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine; The present invention

Be mainly used in hepatic region or the right shoulder pain qi depression to blood stasis of dispelling;

lignum Sappan:sweet; Salty; Flat; Nontoxic, return careful; Liver; Stomach; Large intestine channel, blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain, housewife people's amenorrhea due to stagnation of blood, dysmenorrhea, postpartum stagnation cardiac and abdominal pain, puerperal blood faints, carbuncle, traumatic injury, tetanus; The present invention is mainly used in hepatic region or the right shoulder pain qi depression to blood stasis of dispelling;

radix Et Rhizoma Rhei:bitter in the mouth, cold in nature.Return stomach, spleen, large intestine, liver, pericardium channel, there is purging heat to relax the bowels effect,, constipation stagnant for Gastrointestinal excess heat, abdominal part distension, pain with tenderness, there is removing toxicity for eliminating carbuncles effect, for pathopyretic ulcer, sudden and violent acute conjunctivitis pain, aphtha of the mouth and tongue, gingivitis, there is the clots absorbing effect of stimulating the menstrual flow, for menstruation apolipsis, postpartum stagnation, the lump in the abdomen of stagnation of blood stasis, and traumatic injury, swelling and pain due to blood stasis, there is removing damp-heat effect, for jaundice, dysuria, the constipation with dry stool of stagnation of damp-heat; Pyretic stranguria, stranguria caused by urinary stone, as BAZHENG SAN, have cooling blood for hemostasis, for haematemesis, the epistaxis of injury of blood collaterals by heat, have blood in stool, metrorrhagia, leucorrhea with red and white discharge; The present invention is mainly used in constipation with relieving constipation;

radix Notoginseng powder:hemostasis, dissipating blood stasis, detumescence, analgesic therapy, controls haematemesis, hemoptysis, epistaxis, has blood in stool, dysentery, metrorrhagia ， mass in the abdomen, puerperal blood faints, retention of lochia, falls and flutters blood stasis, traumatic hemorrhage, carbuncle pain; The present invention is mainly used in promoting blood circulation and hemostasis;

radix Trichosanthis:sweet, micro-hardship, is slightly cold, attaches to the lung and stomach meridians, and clearing away heat and promoting production of body fluid, detumescence and apocenosis, for calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin; The present invention is mainly used in cough-relieving and promotes the production of body fluid.

All medicine compatibilities above, play effect of replenishing QI to invigorate the spleen, dispersing the stagnated liver-QI for regulating the stomach, dissolving blood stasis and detoxication, hard masses softening and resolving, and make simple, taking convenience, have no side effect, cheap.

The present invention has good result by clinical trial, and two group of 60 routine middle and terminal cancer patient all adopted to Seldinger technology percutaneous femoral artery puncture, conduit is inserted to Hepatic artery and feeding artery carries out chemoembolization; A group is simple hepatic arterial chemoembolization, and B group is the postoperative treatment by Chinese herbs of carrying out, and two groups relatively in table 1,2

Table 1: survival rate situation

?	0.5 year	1 year	2 years	3 years
					A group	90.5%	80.4%	45%	20.1%
B group	96%	86.5%	68.2%	35.5%

Table 2: quality of life situation (symptom occurrence rate in life cycle)

?	Stomachache	Heating	Symptom of digestive tract	Other
					A group	22.6%	19.9%	69.9%	38.8%
B group	11.6%	3%	6%	?

Can find out by above-mentioned two tables, B group patient's survival rate is apparently higher than A group, and especially the survival rate of the 3rd year, learns X by statistics ²inspection, shows notable difference (p ﹤ 005), illustrates that the treatment of Chinese medicine is of value to long-term curative effect; Quality of life aspect, B group patient also apparently higher than A group, and statistically have notable difference (p ﹤ 005), illustrate that the patient of Chinese medicine partner treatment can obtain good life quality; Other refer to affect other factors of patients ' life quality, as bad in weak, emotional lability, sleep etc.; By the treatment of Chinese herbal medicine, after 3 years, still there are 12 routine patient's survivals, stable disease at present.

detailed description of the invention:

Embodiment 1: to make an auxiliary medicine agent as example, get 60 grams of the Radixs Astragali, 10 grams of Radix Bupleuri, 30 grams of the Radix Paeoniae Albas, 15 grams of Rhizoma Atractylodis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 30 grams of Polyporus, 30 grams, Poria, 60 grams of Herba Scutellariae Barbataes, 15 grams of Rhizoma Cyperis, 30 grams, thatch rice, 30 grams of Herba Artemisiae Scopariaes, 15 grams of Radix Salviae Miltiorrhizae Tabellae, 5 grams of Squama Maniss, 30 grams of Herba Lycopi, 30 grams of Rhizoma Alismatis, 10 grams of Endothelium corneum, each 10 grams of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 6 grams, Radix Glycyrrhizae; First above-mentioned raw material is mixed and is put in medicinal cupping, then put 3, Rhizoma Zingiberis Recens, then to injected water in medicinal cupping, water will soak medical herbs, soaked and decocted after 20-30 minutes, decocted altogether 2 times, 400-500 liters of extracting juice, take for 1-2 days, and this formula is suitable for all patients.

Embodiment 2: to make an auxiliary medicine agent as example, get 60 grams of the Radixs Astragali, 15 grams of Radix Bupleuri, 30 grams of the Radix Paeoniae Albas, 15 grams of Rhizoma Atractylodis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 30 grams of Polyporus, 30 grams, Poria, 60 grams of Herba Scutellariae Barbataes, 15 grams of Rhizoma Cyperis, 30 grams, thatch rice, 30 grams of Herba Artemisiae Scopariaes, 15 grams of Radix Salviae Miltiorrhizae Tabellae, 5 grams of Squama Maniss, 30 grams of Herba Lycopi, 30 grams of Rhizoma Alismatis, 15 grams of Endothelium corneum, each 15 grams of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 6 grams, Radix Glycyrrhizae; Add again 15-30 grams, the Radix Rehmanniae, 15 grams of Radix Cynanchi Atratis; Manufacture method is with embodiment 1, the patient that this formula is suitable for having a low fever.

Embodiment 3: to make an auxiliary medicine as example, get 30 grams of the Radixs Astragali, 10 grams of Radix Bupleuri, 15 grams of the Radix Paeoniae Albas, 10 grams of Rhizoma Atractylodis, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of Polyporus, 15 grams, Poria, 30 grams of Herba Scutellariae Barbataes, 10 grams of Rhizoma Cyperis, 15 grams, thatch rice, 15 grams of Herba Artemisiae Scopariaes, 10 grams of Radix Salviae Miltiorrhizae Tabellae, 3 grams of Squama Maniss, 15 grams of Herba Lycopi, 15 grams of Rhizoma Alismatis, 10 grams of Endothelium corneum, each 10 grams of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 6 grams, Radix Glycyrrhizae; Add again 15-30 grams of Rhizoma Corydalis, 10-15 grams of Radix Curcumaes, 10-15 grams of Lignum Sappans; Manufacture method is with embodiment 1, and this formula is suitable for the patient of hepatic region or right shoulder and back ache.

Embodiment 4: to make an auxiliary medicine as example, get 50 grams of the Radixs Astragali, 10 grams of Radix Bupleuri, 20 grams of the Radix Paeoniae Albas, 15 grams of Rhizoma Atractylodis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams of Polyporus, 20 grams, Poria, 40 grams of Herba Scutellariae Barbataes, 10 grams of Rhizoma Cyperis, 20 grams, thatch rice, 20 grams of Herba Artemisiae Scopariaes, 15 grams of Radix Salviae Miltiorrhizae Tabellae, 4 grams of Squama Maniss, 20 grams of Herba Lycopi, 20 grams of Rhizoma Alismatis, 10 grams of Endothelium corneum, each 10 grams of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 6 grams, Radix Glycyrrhizae; Add 6-10 grams of Radix Et Rhizoma Rhei, manufacture method difference from Example 1 is Radix Notoginseng powder mixing in water for oral taking again, and this formula is suitable for the patient of constipation.

Embodiment 5, to make an auxiliary medicine as example, gets 40 grams of the Radixs Astragali, 15 grams of Radix Bupleuri, 25 grams of the Radix Paeoniae Albas, 10 grams of Rhizoma Atractylodis, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 25 grams of Polyporus, 25 grams, Poria, 50 grams of Herba Scutellariae Barbataes, 15 grams of Rhizoma Cyperis, 25 grams, thatch rice, 25 grams of Herba Artemisiae Scopariaes, 15 grams of Radix Salviae Miltiorrhizae Tabellae, 3 grams of Squama Maniss, 25 grams of Herba Lycopi, 25 grams of Rhizoma Alismatis, 10 grams of Endothelium corneum, each 15 grams of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 6 grams, Radix Glycyrrhizae; Add again 6-10 grams of Radix Notoginseng powder; Manufacture method difference from Example 1 is Radix Notoginseng powder mixing in water for oral taking, and this formula is suitable for the patient of tooth epistaxis.

Embodiment 6: to make an auxiliary medicine as example, get 50 grams of the Radixs Astragali, 10 grams of Radix Bupleuri, 15 grams of the Radix Paeoniae Albas, 15 grams of Rhizoma Atractylodis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of Polyporus, 15 grams, Poria, 45 grams of Herba Scutellariae Barbataes, 10 grams of Rhizoma Cyperis, 30 grams, thatch rice, 15 grams of Herba Artemisiae Scopariaes, 10 grams of Radix Salviae Miltiorrhizae Tabellae, 5 grams of Squama Maniss, 15 grams of Herba Lycopi, 15 grams of Rhizoma Alismatis, 15 grams of Endothelium corneum, each 10 grams of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 6 grams, Radix Glycyrrhizae; Add again 15-30 grams of Radix Trichosanthis; Manufacture method is with embodiment 1, and this formula is suitable for thirsty patient.

Embodiment 7: to make an auxiliary medicine as example, get 30 grams of the Radixs Astragali, 15 grams of Radix Bupleuri, 15 grams of the Radix Paeoniae Albas, 10 grams of Rhizoma Atractylodis, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams of Polyporus, 15 grams, Poria, 30 grams of Herba Scutellariae Barbataes, 10 grams of Rhizoma Cyperis, 15 grams, thatch rice, 15 grams of Herba Artemisiae Scopariaes, 10 grams of Radix Salviae Miltiorrhizae Tabellae, 3 grams of Squama Maniss, 15 grams of Herba Lycopi, 15 grams of Rhizoma Alismatis, 15 grams of Endothelium corneum, each 15 grams of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 6 grams, Radix Glycyrrhizae; If having a low fever, patient adds again 15-30 grams, the Radix Rehmanniae, 15 grams of Radix Cynanchi Atratis; If patient's abdominal distention adds 15-30 grams of Rhizoma Corydalis, 10-15 grams of Radix Curcumaes, 10-15 grams of Lignum Sappans again; If patient's constipation adds 6-10 grams of Radix Et Rhizoma Rhei again, if patient's tooth epistaxis adds 6-10 grams of Radix Notoginseng powder again; If thirsty 15-30 grams of the Radix Trichosanthis that add again of patient; First above-mentioned raw material is mixed, clean up; Again cleaned raw material is put into drying baker and dry, then grind to form graininess, more ground raw material is sieved with 100 object sieves, the medicine that granule is little filters out, for future use, what granule was large grinds into powder and sieves again, finally reaches the object of sieving; Then 1 kilogram of Mel is put into the refining of pot low baking temperature, solidifying as maltosemalt sugar shape, the not order of stirring is burnt; Finally refined honey is mixed and is rubbed by evenly with above-mentioned medicamental pulverata, place about half an hour, again rub by, make the honeyed pill of 6 grams of left and right, point within 1-2 days, take.

Embodiment 8, difference from Example 7 are that manufacture method, for first above-mentioned raw material being mixed, cleans up; Again cleaned raw material is put into drying baker and dry, then grind to form graininess, more ground raw material is sieved with 100 object sieves, the medicine that granule is little filters out, for future use, what granule was large grinds into powder and sieves again, finally reaches the object of sieving; Finally, taking 6 grams as unit pack, divide and take for 1-2 days.

Embodiment 9: manufacture method finally incapsulates with 0.5 gram as different from Example 8, divides and takes for 1-2 days.

Claims (7)

1. treat a medicine for mid and late liver cancer, it is characterized in that it comprises that following raw material is by weight forming:

The Radix Astragali 6.7-20.4%, Radix Bupleuri 2.1-5.6%, the Radix Paeoniae Alba 3.2-10.8%, Rhizoma Atractylodis 2.1-5.6%, the Rhizoma Atractylodis Macrocephalae 2.1-5.6%, Polyporus 3.2-10.8%, Poria 3.2-10.8%, Herba Scutellariae Barbatae 6.7-20.4%, Rhizoma Cyperi 2.1-5.6%, thatch rice 3.2-10.8%, Herba Artemisiae Scopariae 3.2-10.8%, Radix Salviae Miltiorrhizae Tabellae 2.1-5.6%, Squama Manis 0.6-1.9%, Herba Lycopi 3.2-10.8%, Rhizoma Alismatis 3.2-10.8%, Endothelium corneum 2.1-5.6%, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) are each 6.7-16.2%, Radix Glycyrrhizae 1.2-2.3%.

2. the medicine for the treatment of mid and late liver cancer according to claim 1, it is characterized in that it comprises that following raw material is by weight forming: the Radix Astragali 10.1-15.2%, Radix Bupleuri 2.2-5.2%, the Radix Paeoniae Alba 4.5-6.6%, Rhizoma Atractylodis 2.2-5.2%, the Rhizoma Atractylodis Macrocephalae 2.2-5.2%, Polyporus 4.5-6.6%, Poria 4.5-6.6%, Herba Scutellariae Barbatae 10.1-15.2%, Rhizoma Cyperi 2.2-5.2%, thatch rice 4.5-6.6%, Herba Artemisiae Scopariae 4.5-6.6%, Radix Salviae Miltiorrhizae Tabellae 2.2-5.2%, Squama Manis 0.7-1.6%, Herba Lycopi 4.5-6.6%, Rhizoma Alismatis 4.5-6.6%, Endothelium corneum 2.2-5.2%, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) each 9.1-15.6%, Radix Glycyrrhizae 1.2-2.3%.

3. the medicine for the treatment of mid and late liver cancer according to claim 1 and 2, is characterized in that it also comprises following raw material by weight: the Radix Rehmanniae 4.5-6.6%, Radix Cynanchi Atrati 3.1-5.7%.

4. the medicine for the treatment of mid and late liver cancer according to claim 1 and 2, is characterized in that it also comprises following raw material by weight: Rhizoma Corydalis 4.5-6.6%, Radix Curcumae 2.2-5.2%, Lignum Sappan 2.2-5.2%.

5. the medicine for the treatment of mid and late liver cancer according to claim 1 and 2, is characterized in that it also comprises following raw material by weight: Radix Et Rhizoma Rhei 1.2-3.8%.

6. the medicine for the treatment of mid and late liver cancer according to claim 1 and 2, is characterized in that it also comprises following raw material by weight: Radix Notoginseng powder 1.2-3.8%.

7. the medicine for the treatment of mid and late liver cancer according to claim 1 and 2, is characterized in that it also comprises following raw material by weight: Radix Trichosanthis 4.5-6.6%.