CN105232975A - Preparation for improving symptoms of night sweat and preparation method of preparation - Google Patents
Preparation for improving symptoms of night sweat and preparation method of preparation Download PDFInfo
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Abstract
The invention discloses a preparation for improving symptoms of night sweat and a preparation method of the preparation. The preparation is mainly prepared from the following medicinal raw materials in parts by weight: 8-13 parts of radix bupleuri, 10-15 parts of common cowpea root, 6-9 parts of dark plum, 10-14 parts of white clover herb, 8-15 parts of intermediate peashrub root, 9-14 parts of lily, 7-12 parts of ivy glorybind herb or root, 5-9 parts of franchet groundcherry persistent calyx or fruit, 9-15 parts of dried orange peel, 8-12 parts of wight parnassia herb, 7-13 parts of radix asparagi, 8-14 parts of Yunnan bulbophyllum herb, 7-11 parts of common canscora herb, 6-13 parts of purpleflower violet and 9-12 parts of lotus petiole. The preparation disclosed by the invention, which is mainly prepared from pure natural Chinese herbal medicines through scientific combination and researches, is safe and free from side effect, and the preparation is significant in curative effect, not easy to cause reoccurrence and is capable of treating both symptoms and root causes.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of preparation and the method for making of improving night sweat symptom.
Background technology
Night sweat is a disease name of the traditional Chinese medical science, be after falling asleep sweating abnormal, namely after waking up, antiperspirant is let out is only a kind of symptom of feature.The patient of night sweat, the sleep had and night sweat go out, and after some sleeps to midnight, night sweat goes out, and the firm shut my eyes had is that night sweat goes out a little while.Etiology and pathogenesis: 1, deficiency of the kidney yin: void is the excess of YANG then, raw in deficiency-heat, cloudy gas is hollow, sleeps, defends gas and be absorbed in an opponent's defence in the moon, and table is without escorting, and flesh table is not close, and the fire in honor is solely prosperous in outward, steaming, and leak then antiperspirant in urgent Tianjin.Awake then gas-solid in table, the airtight and perspiration stopped in profound mansion.2, tuberculosis.According to the clinical manifestation of night sweat patient, light-duty, medium-sized and heavy three kinds can be divided into.Light-duty night sweat: the patient of light-duty night sweat, most in sleep deeply, or in the morning 5 time permitted or easily gone out at awake front 1 ~ 2 little perspiration constantly, sweating amount is less, only after awake, thinks that whole body or some position of health are slightly made soaked with sweat, then releases once again without perspiration after awake.General without uncomfortable sensation.Medium-sized night sweat: the patient of medium-sized night sweat, most fall asleep after soon perspiration can release, the dress that very then can make to sleep is drenched, and after waking up, namely antiperspirant stop, and after cleaning perspiration with it, then falls asleep and namely no longer perspires.Such night sweat, patient Chang You warms sense, hotwork sweating, sometimes occurs the sensation of dry mouth and throat after awake.Heavy night sweat: the patient of heavy night sweat, perspiration very easily releases.Soon close eye after sleep or just by when falling asleep, namely have antiperspirant to pour out night, can wake up with a start after sweating, after waking up, perspiration can be restrained suddenly.Falling asleep can sweating again again.Volume of perspiration is large, and perspiration is often with light saline taste, or sweating is mixed with fetid sweat simultaneously.Sweating notably can make bedding soak, one night non-several replace dress of sleeping and then cannot sleep peacefully, have and heavily demonstrate,prove patient bedding can be made to drench individually, bedding is thinner or when using mat, perspiration can print off antiperspirant mark on bed board.These patients are often with significantly warming sense, and the agitation that mood also shows, dry mouth and tougue after antiperspirant, likes cold water.At ordinary times can with low grade fever or hectic fever, dysphoria with feverish sensation in the chest palms and soles, flushed cheeks, dizzy, become thin, be weary, urine color depth, urine volume is few, is hard and dry.
The clinical syndrome differentiation typing of night sweat is divided into deficiency of heart-blood and hyperactivity of fire caused by deficiency of YIN two type more.Deficiency of heart-blood, often shows as then sweating of sleeping, awake then perspiration stopped, palpitation and sleeplessness, lustreless complexion, shortness of breath and tired spirit.Pale tongue with thin fur, deficient pulse.Control suitable replenishing blood for nourishing heart arresting sweating, can Yangxin Decoction be selected: Semen Platycladi 12 grams, Semen Ziziphi Spinosae 30 grams, Radix Polygalae 12 grams, Flos Albiziae 15 grams, Caulis Polygoni Multiflori 30 grams, Colla cornus cervi 10 grams, Colla Plastri Testudinis 6 grams, Radix Ophiopogonis 12 grams, Radix Angelicae Sinensis 15 grams, the Radix Paeoniae Alba 20 grams, 20 grams, the Radix Rehmanniae, Rhizoma Coptidis 3 grams, Poria cum Radix Pini 15 grams, Radix Codonopsis 20 grams, the Radix Astragali 30 grams, 6 grams, Radix Glycyrrhizae, is decocted in water for oral dose.Anshen Wan, GUIPI WAN are oral.Hyperactivity of fire caused by deficiency of YIN, often occur hectic fever night sweat, fidgets due to deficiency is slept less, dysphoria with feverish sensation in the chest palms and soles, emaciated physique.Woman's menoxenia, man's nocturnal emission.The few tongue of red tongue, stringy,thready and rapid pulse.Control suitable nourishing YIN to lower pathogenic fire, can yin-nourishing soup be selected: Rhizoma Polygonati 15 grams, Rhizoma Polygonati Odorati 12 grams, Radix Adenophorae (Radix Glehniae) 15 grams, Radix Ophiopogonis 15 grams, Radix Asparagi 12 grams, Fructus Mori 20 grams, Radix Angelicae Sinensis 15 grams, 20 grams, the Radix Rehmanniae, 20 grams, Radix Rehmanniae Preparata, Cortex Phellodendri 10 grams, Radix Scutellariae 10 grams, Rhizoma Coptidis 3 grams, the Radix Astragali 30 grams, 12 grams, Folium Bambusae, Herba Ecliptae 15 grams, 6 grams, Radix Glycyrrhizae, is decocted in water for oral dose.Know that cypress ball, Pearl Pill are oral.
Application publication number CN103191303A(application number 201310139759.3) Chinese patent literature disclose one and treat night sweat Chinese medicine, be made up of following prescription and weight: Radix Rehmanniae Preparata 10-15 gram, Radix Astragali 10-15 gram, Semen Ziziphi Spinosae 10-15 gram, Cortex Lycii 6-15 gram, Concha Ostreae (calcined) 10-30 gram, Carapax et Plastrum Testudinis 10-24 gram, Rhizoma Polygonati Odorati 8-12 gram, Rhizoma Anemarrhenae 6-12 gram, Radix Paeoniae Alba 5-10 gram, Fructus Corni 5-10 gram, Radix Ephedrae 5-10 gram, Cortex Phellodendri 3-10 gram, Radix Stellariae 3-10 gram, Radix Glycyrrhizae 3-10 gram, Fructus Schisandrae Chinensis 2-4 gram.Application publication number CN103550521A(application number 201310549362.1) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of night sweat, this Chinese medicine composition is by Cortex Lycii, the Radix Astragali, Poria, Radix Ophiopogonis, Fructus Aurantii Immaturus, Fructus Corni, Fructus Lycii, the Pseudobulbus Bletillae (Rhizoma Bletillae), Semen Persicae, Testa sojae atricolor, Os Draconis, Radix Glycyrrhizae is made.Application publication number CN103800691A(application number 201410065797.3) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of night sweat, its raw material of Chinese medicine and weight are: Rhizoma Anemarrhenae 5-25 part, Radix Salviae Miltiorrhizae 10-40 part, Herba Ecliptae 5-25 part, Rhizoma Chuanxiong 5-25 part, Radix Rehmanniae 10-30 part, Cortex Lycii 5-25 part, Rhizoma Atractylodis Macrocephalae 5-25 part, Fructus Ligustri Lucidi 10-30 part, Caulis Perillae 5-25 part, Radix Ephedrae 10-30 part, Fructus Corni 5-25 part, Radix Aucklandiae 5-10 part, Poria 5-25 part, Fructus Gardeniae 5-25 part, Radix Scutellariae 5-20 part, Rhizoma Alismatis 5-25 part, Cortex Phellodendri 5-25 part, Carapax Trionycis 5-25 part, Herba Dendrobii 5-25 part, Radix Glycyrrhizae 5-15 part.Application publication number CN104208401A(application number 201410437228.7) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of night sweat, be made up of the raw material of Chinese medicine of following weight portion: Semen sojae atricolor 12-18 part, Radix Rehmanniae Preparata 10-15 part, Radix Asparagi 8-12 part, Fructus Mori 10-15 part, Galla Chinensis 3-8 part, Herba Epimedii 4-8 part, Radix Puerariae 1-3 part, Fructus Schisandrae Chinensis 5-10 part, Cortex Phellodendri 5-10 part, Carapax Et Plastrum Testudinis 2-5 part, Radix Paeoniae Alba 1-5 part, Cortex Lycii 0.5-2 part, Radix Ophiopogonis 1-3 part, Concha Haliotidis 1-5 part, Rhizoma Cibotii 1-3 part.
At present, doctor trained in Western medicine there is no the specific medicament for the treatment of night sweat, and the Chinese medicine of existing treatment night sweat, effect is not remarkable.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of preparation and the method for making of improving night sweat symptom.The present invention is primary raw material with pure natural Chinese herbal medicine, develops through scientific compatibility, safely, has no side effect, evident in efficacy, and treating both the principal and secondary aspects of a disease, not easily recurs.
Technical scheme of the present invention is:
Improve the preparation of night sweat symptom, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Bupleuri 8-13, Radix vignae sinensis 10-15, Fructus Mume 6-9, Herba Trifolii Pepentis 10-14, Radix Caraganae intermediae 8-15, Bulbus Lilii 9-14, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 7-12, Calyx seu Fructus physalis 5-9, Pericarpium Citri Reticulatae 9-15, Herba Parnassiae Wightianae 8-12, Radix Asparagi 7-13, Herba Bulbophylli inconspicui 8-14, Herba Canscorae 7-11, stone maple medicine 6-13, Petiolus nelumbinis 9-12.
Improve the preparation of night sweat symptom, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Bupleuri 9-11, Radix vignae sinensis 11-14, Fructus Mume 7-8, Herba Trifolii Pepentis 11-13, Radix Caraganae intermediae 10-13, Bulbus Lilii 11-13, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 9-11, Calyx seu Fructus physalis 6-8, Pericarpium Citri Reticulatae 10-14, Herba Parnassiae Wightianae 9-11, Radix Asparagi 8-11, Herba Bulbophylli inconspicui 10-12, Herba Canscorae 8-10, stone maple medicine 8-11, Petiolus nelumbinis 10-11.
Improve the preparation of night sweat symptom, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Bupleuri 10, Radix vignae sinensis 12, Fructus Mume 7.5, Herba Trifolii Pepentis 12, Radix Caraganae intermediae 11, Bulbus Lilii 12, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 10, Calyx seu Fructus physalis 7, Pericarpium Citri Reticulatae 12, Herba Parnassiae Wightianae 10, Radix Asparagi 9, Herba Bulbophylli inconspicui 11, Herba Canscorae 9, stone maple medicine 10, Petiolus nelumbinis 10.5.
Present invention also offers the preparation method aforementioned preparation improving night sweat symptom being made pharmaceutically acceptable decoction, pill, thick paste agent and granule.
The preparation method of described decoction is:
(1) cleaned by Radix Bupleuri, water logging 6-8 hour (preferred water logging 7 hours), pulls out, section, gets Mel, and the weight of Mel is the weight of the preferred Mel of 1/5-1/3(of Radix Bupleuri weight is 1/4 of Radix Bupleuri weight), old honey is smelt with slow fire, tableted Radix Bupleuri is poured into, fries 14-26 minute (preferably frying 20 minutes), take the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, cross No. seven sieves;
(2) get Fructus Mume, clean, add 8-11 times of water gaging (preferably adding 9 times of water gagings), soak 25 minutes, decoct 32-56 minute (preferably decocting 48 minutes), filter and remove residue, medicinal liquid is for subsequent use;
(3) get Bulbus Lilii, soak 12 hours, drop goes out moisture, put into soy bean milk making machine, add water, the consumption of water is 10-13 times (consumption of preferred water is 11 times of Bulbus Lilii weight) of Bulbus Lilii weight, select Five-grain soybean milk pattern, beat 12-18 minute (preferably making a call to 16 minutes), must starch for subsequent use;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 5.4-7.4 times (preferred amount of water is 6.6 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) step (2), step (3) and step (4) gained are mixed, add step (1) gained, stir evenly.
The preparation method of described pill is:
(1) cleaned by Radix Bupleuri, water logging 6-8 hour (preferred water logging 7 hours), pulls out, section, gets Mel, and the weight of Mel is the weight of the preferred Mel of 1/5-1/3(of Radix Bupleuri weight is 1/4 of Radix Bupleuri weight), old honey is smelt with slow fire, tableted Radix Bupleuri is poured into, fries 14-26 minute (preferably frying 20 minutes), take the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, cross No. five sieves;
(2) get Fructus Mume, clean, add 8-11 times of water gaging (preferably adding 9 times of water gagings), soak 25 minutes, decoct 32-56 minute (preferably decocting 48 minutes), filter and remove residue, medicinal liquid is for subsequent use;
(3) Bulbus Lilii is got, soak 12 hours, drop goes out moisture, put into soy bean milk making machine, add water, the consumption of water is 10-13 times (consumption of preferred water is 11 times of Bulbus Lilii weight) of Bulbus Lilii weight, select Five-grain soybean milk pattern, beat 12-18 minute (preferably making a call to 16 minutes), by standing for gained serosity 3 hours, it was for subsequent use to get upper liquid;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 5.4-7.4 times (preferred amount of water is 6.6 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) by step (2) and the mixing of step (4) gained, be condensed into the ointment (being preferably condensed into the ointment that relative density is 1.3) that relative density is 1.28-1.32, dry, pulverize into fine powder, cross No. five sieves;
(6) by step (1) and the mixing of step (5) gained, with the general ball of step (3) gained, the pill that particle diameter is 3mm is made, dry, to obtain final product.
The preparation method of described thick paste agent is:
(1) cleaned by Radix Bupleuri, water logging 6-8 hour (preferred water logging 7 hours), pulls out, section, gets Mel, and the weight of Mel is the weight of the preferred Mel of 1/5-1/3(of Radix Bupleuri weight is 1/4 of Radix Bupleuri weight), old honey is smelt with slow fire, tableted Radix Bupleuri is poured into, fries 14-26 minute (preferably frying 20 minutes), take the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, cross No. five sieves;
(2) get Fructus Mume, clean, add 8-11 times of water gaging (preferably adding 9 times of water gagings), soak 25 minutes, decoct 32-56 minute (preferably decocting 48 minutes), filter and remove residue, medicinal liquid is for subsequent use;
(3) get Bulbus Lilii, soak 12 hours, drop goes out moisture, put into soy bean milk making machine, add water, the consumption of water is 10-13 times (consumption of preferred water is 11 times of Bulbus Lilii weight) of Bulbus Lilii weight, select Five-grain soybean milk pattern, beat 12-18 minute (preferably making a call to 16 minutes), must starch for subsequent use;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 5.4-7.4 times (preferred amount of water is 6.6 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) step (2), step (3) and step (4) gained are mixed, leave standstill 10 hours, get upper liquid, be condensed into the ointment (being preferably condensed into the ointment that relative density is 1.3) that relative density is 1.28-1.32, add step (1) gained fine powder, mix well, add refined honey, every 100kg ointment adds the preferred every 100kg ointment of refined honey 134-150kg(and adds refined honey 142kg), micro-refining, foam removal, seals and get final product in dress aseptic bottle.
The preparation method of described granule is:
(1) cleaned by Radix Bupleuri, water logging 6-8 hour (preferred water logging 7 hours), pulls out, section, gets Mel, and the weight of Mel is the weight of the preferred Mel of 1/5-1/3(of Radix Bupleuri weight is 1/4 of Radix Bupleuri weight), old honey is smelt with slow fire, tableted Radix Bupleuri is poured into, fries 14-26 minute (preferably frying 20 minutes), take the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, cross No. five sieves;
(2) get Fructus Mume, clean, add 8-11 times of water gaging (preferably adding 9 times of water gagings), soak 25 minutes, decoct 32-56 minute (preferably decocting 48 minutes), filter and remove residue, medicinal liquid is for subsequent use;
(3) Bulbus Lilii is got, soak 12 hours, drop goes out moisture, put into soy bean milk making machine, add water, the consumption of water is 10-13 times (consumption of preferred water is 11 times of Bulbus Lilii weight) of Bulbus Lilii weight, select Five-grain soybean milk pattern, beat 12-18 minute (preferably making a call to 16 minutes), by standing for gained serosity 3 hours, it was for subsequent use to get upper liquid;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 5.4-7.4 times (preferred amount of water is 6.6 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) by step (2) and the mixing of step (4) gained, be condensed into the ointment (being preferably condensed into the ointment that relative density is 1.3) that relative density is 1.28-1.32, dry, pulverize into fine powder, cross No. five sieves;
(6) by step (1) and the mixing of step (5) gained, add step (3) gained and make soft material, 16-20 mesh sieve is granulated (preferably granulating on 18 mesh sieves), and make uniform granule, drying, granulate, sub-sieve, to obtain final product.
The preparation improving night sweat symptom provided by the invention is primary raw material with pure natural Chinese herbal medicine, develops through scientific compatibility.In addition, excellent results of the present invention also shows:
1, the preparation method of various dosage form is simple, products obtained therefrom taking convenience;
, have no side effect 2, safely;
3, treating both the principal and secondary aspects of a disease, not easily recurs;
4, there is effect of invigorating the spleen and benefiting QI, nourishing YIN and moistening the lung, lung heat clearing pathogenic fire reducing, regulating QI to expel dampness, clearing away heart-fire for tranquillization, soothing the liver yang invigorating, evident in efficacy.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1improve the preparation of night sweat symptom, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): Radix Bupleuri 8 parts, Radix vignae sinensis 10 parts, Fructus Mume 6 parts, Herba Trifolii Pepentis 10 parts, Radix Caraganae intermediae 8 parts, Bulbus Lilii 9 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 7 parts, Calyx seu Fructus physalis 5 parts, Pericarpium Citri Reticulatae 9 parts, Herba Parnassiae Wightianae 8 parts, Radix Asparagi 7 parts, Herba Bulbophylli inconspicui 8 parts, Herba Canscorae 7 parts, stone maple medicine 6 parts, Petiolus nelumbinis 9 parts.
The above-mentioned preparation method improving the preparation decoction of night sweat symptom is:
(1) cleaned by Radix Bupleuri, water logging 6 hours, pulls out, section, and get Mel, the weight of Mel is 1/5 of Radix Bupleuri weight, is smelt old honey with slow fire, is poured into by tableted Radix Bupleuri, fries 14 minutes, takes the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, crosses No. seven sieves;
(2) get Fructus Mume, clean, add 8 times of water gagings, soak 25 minutes, decoct 32 minutes, filter and remove residue, medicinal liquid is for subsequent use;
(3) get Bulbus Lilii, soak 12 hours, drop goes out moisture, puts into soy bean milk making machine, adds water, and the consumption of water is 10 times of Bulbus Lilii weight, selects Five-grain soybean milk pattern, makes a call to 12 minutes, must starch for subsequent use;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 5.4 times of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) step (2), step (3) and step (4) gained are mixed, add step (1) gained, stir evenly.
The instructions of taking that gained of the present invention improves the preparation decoction of night sweat symptom is: oral, one day twice, and each 180mL(is warm).
embodiment 2improve the preparation of night sweat symptom, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): Radix Bupleuri 13 parts, Radix vignae sinensis 15 parts, Fructus Mume 9 parts, Herba Trifolii Pepentis 14 parts, Radix Caraganae intermediae 15 parts, Bulbus Lilii 14 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 12 parts, Calyx seu Fructus physalis 9 parts, Pericarpium Citri Reticulatae 15 parts, Herba Parnassiae Wightianae 12 parts, Radix Asparagi 13 parts, Herba Bulbophylli inconspicui 14 parts, Herba Canscorae 11 parts, stone maple medicine 13 parts, Petiolus nelumbinis 12 parts.
The above-mentioned preparation method improving the preparation pill of night sweat symptom is:
(1) cleaned by Radix Bupleuri, water logging 7 hours, pulls out, section, and get Mel, the weight of Mel is 1/4 of Radix Bupleuri weight, is smelt old honey with slow fire, is poured into by tableted Radix Bupleuri, fries 20 minutes, takes the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, crosses No. five sieves;
(2) get Fructus Mume, clean, add 9 times of water gagings, soak 25 minutes, decoct 48 minutes, filter and remove residue, medicinal liquid is for subsequent use;
(3) get Bulbus Lilii, soak 12 hours, drop goes out moisture, puts into soy bean milk making machine, adds water, and the consumption of water is 11 times of Bulbus Lilii weight, selects Five-grain soybean milk pattern, makes a call to 16 minutes, and by standing 3 hours of gained serosity, it was for subsequent use to get upper liquid;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 6.6 times of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) by step (2) and the mixing of step (4) gained, be condensed into the ointment that relative density is 1.3, dry, pulverize into fine powder, cross No. five sieves;
(6) by step (1) and the mixing of step (5) gained, with the general ball of step (3) gained, the pill that particle diameter is 3mm is made, dry, to obtain final product.
model case one:du XX, man, 47 years old.Before 1 year, the symptom that patient just has perspiration to release after there is sleep soon, to examination in hospital, examines as night sweat.After treatment, effect does not show, under the introduction of friend, to our hospital.Patient sleeps night sweat night, and sweating is wet clothing, consciously warms, and hotwork sweating, dry mouth with bitter taste, tongue is partially red, yellow and thin fur, thready and stringy pulse.Take the preparation pill that the present embodiment gained improves night sweat symptom, three times on the one, each 4 balls, warm water takes.Take 7 days, night sweat stops, other transference cure.Follow up a case by regular visits to night sweat not recur.
embodiment 3improve the preparation of night sweat symptom, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): Radix Bupleuri 9 parts, Radix vignae sinensis 11 parts, Fructus Mume 7 parts, Herba Trifolii Pepentis 11 parts, Radix Caraganae intermediae 10 parts, Bulbus Lilii 11 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 9 parts, Calyx seu Fructus physalis 6 parts, Pericarpium Citri Reticulatae 10 parts, Herba Parnassiae Wightianae 9 parts, Radix Asparagi 8 parts, Herba Bulbophylli inconspicui 10 parts, Herba Canscorae 8 parts, stone maple medicine 8 parts, Petiolus nelumbinis 10 parts.
The above-mentioned preparation method improving the preparation thick paste agent of night sweat symptom is:
(1) cleaned by Radix Bupleuri, water logging 7 hours, pulls out, section, and get Mel, the weight of Mel is 1/4 of Radix Bupleuri weight, is smelt old honey with slow fire, is poured into by tableted Radix Bupleuri, fries 20 minutes, takes the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, crosses No. five sieves;
(2) get Fructus Mume, clean, add 9 times of water gagings, soak 25 minutes, decoct 48 minutes, filter and remove residue, medicinal liquid is for subsequent use;
(3) get Bulbus Lilii, soak 12 hours, drop goes out moisture, puts into soy bean milk making machine, adds water, and the consumption of water is 11 times of Bulbus Lilii weight, selects Five-grain soybean milk pattern, makes a call to 16 minutes, must starch for subsequent use;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 6.6 times of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) step (2), step (3) and step (4) gained are mixed, leave standstill 10 hours, get upper liquid, be condensed into the ointment that relative density is 1.3, add step (1) gained fine powder, mix well, add refined honey, every 100kg ointment adds refined honey 142kg, micro-refining, foam removal, seals and get final product in dress aseptic bottle.
model case two:qiu XX, female, 53 years old.Before 2 years, there is slight night sweat symptom in patient, do not give attention, symptom increased the weight of gradually afterwards.Once took multi-medicament treatment, Relapse rate shows effect, and fails to effect a radical cure.Under the introduction of friend, to our hospital.Patient sleeps sweating night as washed, and perspiration, with light saline taste, needs to change nightwear and bedding every day, and with irritable, dry mouth and tougue, is weary, dimly red tongue, and yellow fur is slightly greasy, thready pulse.Take the preparation thick paste agent that the present embodiment gained improves night sweat symptom, three times on the one, each 10g, boiled water is taken after mixing it with water.Take 5 days, night sweat obviously alleviates, without changing nightwear and bedding every day.Take 10 days, night sweat stops, other transference cure.Follow up a case by regular visits to night sweat not recur.
embodiment 4improve the preparation of night sweat symptom, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): Radix Bupleuri 11 parts, Radix vignae sinensis 14 parts, Fructus Mume 8 parts, Herba Trifolii Pepentis 13 parts, Radix Caraganae intermediae 13 parts, Bulbus Lilii 13 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 11 parts, Calyx seu Fructus physalis 8 parts, Pericarpium Citri Reticulatae 14 parts, Herba Parnassiae Wightianae 11 parts, Radix Asparagi 11 parts, Herba Bulbophylli inconspicui 12 parts, Herba Canscorae 10 parts, stone maple medicine 11 parts, Petiolus nelumbinis 11 parts.
The above-mentioned preparation method improving the preparation granules agent of night sweat symptom is:
(1) cleaned by Radix Bupleuri, water logging 7 hours, pulls out, section, and get Mel, the weight of Mel is 1/4 of Radix Bupleuri weight, is smelt old honey with slow fire, is poured into by tableted Radix Bupleuri, fries 20 minutes, takes the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, crosses No. five sieves;
(2) get Fructus Mume, clean, add 9 times of water gagings, soak 25 minutes, decoct 48 minutes, filter and remove residue, medicinal liquid is for subsequent use;
(3) get Bulbus Lilii, soak 12 hours, drop goes out moisture, puts into soy bean milk making machine, adds water, and the consumption of water is 11 times of Bulbus Lilii weight, selects Five-grain soybean milk pattern, makes a call to 16 minutes, and by standing 3 hours of gained serosity, it was for subsequent use to get upper liquid;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 6.6 times of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) by step (2) and the mixing of step (4) gained, be condensed into the ointment that relative density is 1.3, dry, pulverize into fine powder, cross No. five sieves;
(6) by step (1) and the mixing of step (5) gained, add step (3) gained and make soft material, 18 mesh sieves are granulated, makes uniform granule, drying, granulate, sub-sieve, to obtain final product.
model case three:king XX, female, 38 years old.Before more than 1 year, there is night sweat symptom in patient, and once take multi-medicament treatment, symptom without improvement, and increases the weight of.Under the introduction of friend, to our hospital.Patient's flushed cheeks, xerostomia, night sweat is as washed every night, susceptible to lose temper due to restlessness, and urine color depth, urine volume is few, is hard and dry.Red and uncoated tongue, thready and rapid pulse.Take the preparation granules agent that the present embodiment gained improves night sweat symptom, three times on the one, each 10g, boiled water is taken after mixing it with water.Take one week, night sweat stops, other transference cure.Follow up a case by regular visits to night sweat not recur.
embodiment 5improve the preparation of night sweat symptom, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): Radix Bupleuri 10 parts, Radix vignae sinensis 12 parts, Fructus Mume 7.5 parts, Herba Trifolii Pepentis 12 parts, Radix Caraganae intermediae 11 parts, Bulbus Lilii 12 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 10 parts, Calyx seu Fructus physalis 7 parts, Pericarpium Citri Reticulatae 12 parts, Herba Parnassiae Wightianae 10 parts, Radix Asparagi 9 parts, Herba Bulbophylli inconspicui 11 parts, Herba Canscorae 9 parts, stone maple medicine 10 parts, Petiolus nelumbinis 10.5 parts.
The above-mentioned preparation method improving the preparation decoction of night sweat symptom is:
(1) cleaned by Radix Bupleuri, water logging 7 hours, pulls out, section, and get Mel, the weight of Mel is 1/4 of Radix Bupleuri weight, is smelt old honey with slow fire, is poured into by tableted Radix Bupleuri, fries 20 minutes, takes the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, crosses No. seven sieves;
(2) get Fructus Mume, clean, add 9 times of water gagings, soak 25 minutes, decoct 48 minutes, filter and remove residue, medicinal liquid is for subsequent use;
(3) get Bulbus Lilii, soak 12 hours, drop goes out moisture, puts into soy bean milk making machine, adds water, and the consumption of water is 11 times of Bulbus Lilii weight, selects Five-grain soybean milk pattern, makes a call to 16 minutes, must starch for subsequent use;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 6.6 times of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) step (2), step (3) and step (4) gained are mixed, add step (1) gained, stir evenly.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Bupleuri: base is former: be the dry root of umbelliferae bupleurum or Radix Bupeuri Scorzonerfolii..The property of medicine: bitter, is slightly cold.Return liver, gallbladder meridian.Function cures mainly: reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis.
Radix vignae sinensis: base is former: be the root of leguminous plant Semen vignae sinensis.The property of medicine: sweet; Flat.Return spleen, stomach warp.Function cures mainly: invigorating the spleen and benefiting QI; Removing food stagnancy; Removing toxic substances.Main weakness of the spleen and stomach; Food stagnation; Leucorrhea; Stranguria with turbid discharge; Hemorrhoidal bleeding; Furuncle.
Fructus Mume: base is former: for rose department plant plum almost ripe fruit is through the smoked roasting person of processing.The property of medicine: sour in the mouth; Property is put down.Return liver, spleen, lung, kidney, stomach, large intestine channel.Function cures mainly: astringing lung-QI and relieving cough, relieving diarrhea with astringents, and hemostasis, promotes the production of body fluid, relieving colic caused by ascaris.Main chronic cough, deficiency-heat excessive thirst, chronic malaria, chronic diarrhea, dysentery, has blood in stool, hematuria, metrorrhagia, and the ascariasis of biliary tract is suffered from abdominal pain, vomiting, ancylostomiasis.
Herba Trifolii Pepentis: base is former: be the herb of leguminous plant T.repens.The property of medicine: taste is micro-sweet; Property is put down.GUIXIN, spleen channel.Function cures mainly: heat clearing away; Removing heat from blood; Mind calming.Main insane disease; Bleeding hemorrhoids; Scleroma lump.
Radix Caraganae intermediae: base is former: be the root of leguminous plant Caragana intermedia.The property of medicine: micro-pungent; Temperature.GUIXIN, Liver Channel.Function cures mainly: supplementing QI and nourishing YIN.Main dizziness, cardiopalmus, shortness of breath and fatigue, hypertension.
Bulbus Lilii: base is former: be the dry meat scale leaf of liliaceous plant tiger lily, Bulbus Lilii or Lilium tenuifolium.The property of medicine: sweet, cold.GUIXIN, lung meridian.Function cures mainly: nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.For deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, absentminded.
Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae): base is former: be the herb of Convolvulaceae calystegia plant DAWANHUA.The property of medicine: sweet, micro-hardship, flat.Function cures mainly: spleen invigorating, dampness removing, regulating menstruation.Cure mainly weakness of the spleen and stomach, dyspepsia, infantile milk regurgitation, infantile malnutrition, five types of stranguria, leukorrhagia, menoxenia.
Calyx seu Fructus physalis: base is former: be the fruit of the band Constellation calyx of plant of Solanaceae Calyx seu Fructus physalis and Calyx seu fructus physalis.The property of medicine: sour in the mouth; Sweet; Cold in nature.Return lung, kidney channel.Function cures mainly: removing heat from the lung and relieving sorethroat, changes dysentery diuretic.Main lung-heat productive cough, laryngopharynx swelling and pain, hectic fever due to YIN-deficiency consumptive fever, urine leaching is puckery, sky bleb eczema.
Pericarpium Citri Reticulatae: base is former: be the dry mature skin of rutaceae orange and variety thereof.The property of medicine: bitter, pungent, temperature.Return lung, spleen channel.Function cures mainly: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Herba Parnassiae Wightianae: base is former: be the herb of saxifragaceae plant clavus Herba parnassiae.The property of medicine: lightly seasoned, cool in nature.Return lung, spleen channel.
Function cures mainly: tonifying the lung and stopping cough; Hemostasis; Dampness removing.Cure mainly cough due to lung-heat, spitting of blood, spit blood, renal calculus, cholelithiasis, leucorrhea, damp and hot sore.
Radix Asparagi: base is former: be the tuber of liliaceous plant Radix Asparagi.The property of medicine: sweet in the mouth; Bitter; Cold in nature.Return lung, kidney channel.Function cures mainly: nourshing Yin and drynsessmoistening prescription, lung heat clearing pathogenic fire reducing.Main cough caused by dryness-heat, deficiency of YIN chronic cough, consumption of YIN caused by febrile disease, interior-heat is quenched one's thirst, dryness of the intestine constipation, laryngopharynx swelling and pain.
Herba Bulbophylli inconspicui: base is former: be the herb of orchid Herba Bulbophylli inconspicui.The property of medicine: sweet; Pungent; Cool; Nontoxic.Attach to the lung and stomach meridians.Function cures mainly: heat clearing away YIN nourishing; Nourishing the lung to arrest cough.Main cough due to lung-heat; Pulmonary tuberculosis is spat blood; Have sore throat; Calentura excessive thirst; Rheumatic arthralgia; Menoxenia; Traumatic injury.
Herba Canscorae: base is former: be the herb of gentianaceae plant Herba Canscorae.The property of medicine: micro-sweet; Micro-hardship; Cool in nature.Return lung, spleen, stomach, Liver Channel.Function cures mainly: heat-clearing and toxic substances removing; Vital energy regualting and blood circulation-promoting.Main cough due to lung-heat; Hepatitis; Leptospirosis; Chest pain; Stomachache; Traumatic injury; Venom.
Stone maple medicine: base is former: be the herb of Maguireothamnus speciosus hedyotis tenelliflora Blume.The property of medicine: micro-hardship; Flat; Cold.Function cures mainly: heat-clearing and toxic substances removing; Promoting blood circulation and stopping pain.Main cough due to lung-heat; Chronic hepatitis; Expand; Appendicitis; Dysentery; Acute toothache; Infantile hernia; Traumatic injury; Venom.
Petiolus nelumbinis: base is former: be petiole or the anthocaulus of nymphaeaceae plant lotus.The property of medicine: bitter; Property is put down.Return spleen; Urinary bladder channel.Function cures mainly: expelling summer-heat heat clearing away; Regulating QI to expel dampness.Main heat-damp in summer is uncomfortable in chest does not relax; Have loose bowels; Dysentery; Gonorrhea; Leukorrhagia.
test example 1gained of the present invention improves the clinical practice of the preparation (embodiment 5) of night sweat symptom: in October ,-2012 in June, 2011, screens 280 routine night sweat patients in 3 hospitals.Be divided into two groups at random, experimental group and matched group.Experimental group male 64 example, women 76 example, age 28-67 year, 35.5 years old mean age.Matched group male 65 example, women 75 example, age 28-66 year, 35.2 years old mean age.The physical data no significant difference such as two groups of case sexes, age, state of an illness, have comparability (P > 0.05).
Therapeutic Method: experimental group uses gained of the present invention to improve the preparation of night sweat symptom, using method: oral, one day twice, and each 180mL(is warm).Matched group uses the Drug therapys such as LIUWEI DIHUANG WAN, ZHIBAI DIHUANG WAN, XuHan-ting granule, within five days, is a course for the treatment of.After two groups of patients all treat two courses for the treatment of, carry out Comparison of therapeutic.
Curative effect situation criterion: cure: perspiration stopped, other transference cures; Take a turn for the better: sweating obviously reduces, other symptoms are improved; Invalid: to perspire with other symptoms all without improvement.Always effectively comprise clinical cure and improvement, result is as shown in table 1.
Table 1: gained of the present invention improves the preparation compliance test result of night sweat symptom
Efficacy analysis: after two groups of cases treat two courses for the treatment of, experimental group clinical cure 112 example, take a turn for the better 26 examples, invalid 2 examples, total effective rate 98.57%; Matched group clinical cure 49 example, take a turn for the better 66 examples, invalid 25 examples, total effective rate 82.14%.The cure rate of experimental group and total effective rate are apparently higher than matched group.The clinical efficacy of experimental group is obviously better than matched group.
The present invention is primary raw material medicine with Radix Bupleuri, Radix vignae sinensis, Fructus Mume and Herba Trifolii Pepentis etc., makes the preparation improving night sweat symptom.In side, Radix Bupleuri reconciling superficies and interior, soothing the liver, yang invigorating.Radix vignae sinensis invigorating the spleen and benefiting QI; Removing food stagnancy; Removing toxic substances.Fructus Mume astringing lung-QI and relieving cough, relieving diarrhea with astringents, hemostasis, promotes the production of body fluid, relieving colic caused by ascaris.Herba Trifolii Pepentis heat clearing away; Removing heat from blood; Mind calming.Radix Caraganae intermediae supplementing QI and nourishing YIN.Bulbus Lilii nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) spleen invigorating, dampness removing, regulating menstruation.Calyx seu Fructus physalis removing heat from the lung and relieving sorethroat, changes dysentery diuretic.Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Herba Parnassiae Wightianae tonifying the lung and stopping cough; Hemostasis; Dampness removing.Radix Asparagi is nourshing Yin and drynsessmoistening prescription, lung heat clearing pathogenic fire reducing.Herba Bulbophylli inconspicui heat clearing away YIN nourishing; Nourishing the lung to arrest cough.Herba Canscorae heat-clearing and toxic substances removing; Vital energy regualting and blood circulation-promoting.Stone maple medicine heat-clearing and toxic substances removing; Promoting blood circulation and stopping pain.The heat clearing away of Petiolus nelumbinis expelling summer-heat; Regulating QI to expel dampness.Many medicines share, and mutually coordinate, play the effect of invigorating the spleen and benefiting QI, nourishing YIN and moistening the lung, lung heat clearing pathogenic fire reducing, regulating QI to expel dampness, clearing away heart-fire for tranquillization, soothing the liver yang invigorating altogether, treating both the principal and secondary aspects of a disease, not easily recurs.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. improve the preparation of night sweat symptom, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Bupleuri 8-13, Radix vignae sinensis 10-15, Fructus Mume 6-9, Herba Trifolii Pepentis 10-14, Radix Caraganae intermediae 8-15, Bulbus Lilii 9-14, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 7-12, Calyx seu Fructus physalis 5-9, Pericarpium Citri Reticulatae 9-15, Herba Parnassiae Wightianae 8-12, Radix Asparagi 7-13, Herba Bulbophylli inconspicui 8-14, Herba Canscorae 7-11, stone maple medicine 6-13, Petiolus nelumbinis 9-12.
2. improve the preparation of night sweat symptom as claimed in claim 1, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Bupleuri 9-11, Radix vignae sinensis 11-14, Fructus Mume 7-8, Herba Trifolii Pepentis 11-13, Radix Caraganae intermediae 10-13, Bulbus Lilii 11-13, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 9-11, Calyx seu Fructus physalis 6-8, Pericarpium Citri Reticulatae 10-14, Herba Parnassiae Wightianae 9-11, Radix Asparagi 8-11, Herba Bulbophylli inconspicui 10-12, Herba Canscorae 8-10, stone maple medicine 8-11, Petiolus nelumbinis 10-11.
3. improve the preparation of night sweat symptom as claimed in claim 1, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Bupleuri 10, Radix vignae sinensis 12, Fructus Mume 7.5, Herba Trifolii Pepentis 12, Radix Caraganae intermediae 11, Bulbus Lilii 12, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 10, Calyx seu Fructus physalis 7, Pericarpium Citri Reticulatae 12, Herba Parnassiae Wightianae 10, Radix Asparagi 9, Herba Bulbophylli inconspicui 11, Herba Canscorae 9, stone maple medicine 10, Petiolus nelumbinis 10.5.
4. the preparation of the improvement night sweat symptom as described in as arbitrary in claims 1 to 3, it is characterized in that, the preparation of this improvement night sweat symptom is made pharmaceutically acceptable decoction, and the preparation method of described decoction is:
(1) cleaned by Radix Bupleuri, water logging 6-8 hour, pulls out, section, and get Mel, the weight of Mel is the 1/5-1/3 of Radix Bupleuri weight, is smelt old honey with slow fire, is poured into by tableted Radix Bupleuri, fries 14-26 minute, takes the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, crosses No. seven sieves;
(2) get Fructus Mume, clean, add 8-11 times of water gaging (preferably adding 9 times of water gagings), soak 25 minutes, decoct 32-56 minute (preferably decocting 48 minutes), filter and remove residue, medicinal liquid is for subsequent use;
(3) get Bulbus Lilii, soak 12 hours, drop goes out moisture, put into soy bean milk making machine, add water, the consumption of water is 10-13 times (consumption of preferred water is 11 times of Bulbus Lilii weight) of Bulbus Lilii weight, select Five-grain soybean milk pattern, beat 12-18 minute (preferably making a call to 16 minutes), must starch for subsequent use;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 5.4-7.4 times (preferred amount of water is 6.6 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) step (2), step (3) and step (4) gained are mixed, add step (1) gained, stir evenly.
5. the preparation of the improvement night sweat symptom as described in as arbitrary in claims 1 to 3, it is characterized in that, the preparation of this improvement night sweat symptom is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) cleaned by Radix Bupleuri, water logging 6-8 hour (preferred water logging 7 hours), pulls out, section, gets Mel, and the weight of Mel is the weight of the preferred Mel of 1/5-1/3(of Radix Bupleuri weight is 1/4 of Radix Bupleuri weight), old honey is smelt with slow fire, tableted Radix Bupleuri is poured into, fries 14-26 minute (preferably frying 20 minutes), take the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, cross No. five sieves;
(2) get Fructus Mume, clean, add 8-11 times of water gaging (preferably adding 9 times of water gagings), soak 25 minutes, decoct 32-56 minute (preferably decocting 48 minutes), filter and remove residue, medicinal liquid is for subsequent use;
(3) Bulbus Lilii is got, soak 12 hours, drop goes out moisture, put into soy bean milk making machine, add water, the consumption of water is 10-13 times (consumption of preferred water is 11 times of Bulbus Lilii weight) of Bulbus Lilii weight, select Five-grain soybean milk pattern, beat 12-18 minute (preferably making a call to 16 minutes), by standing for gained serosity 3 hours, it was for subsequent use to get upper liquid;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 5.4-7.4 times (preferred amount of water is 6.6 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) by step (2) and the mixing of step (4) gained, be condensed into the ointment (being preferably condensed into the ointment that relative density is 1.3) that relative density is 1.28-1.32, dry, pulverize into fine powder, cross No. five sieves;
(6) by step (1) and the mixing of step (5) gained, with the general ball of step (3) gained, the pill that particle diameter is 3mm is made, dry, to obtain final product.
6. the preparation of the improvement night sweat symptom as described in as arbitrary in claims 1 to 3, it is characterized in that, the preparation of this improvement night sweat symptom is made pharmaceutically acceptable thick paste agent, and the preparation method of described thick paste agent is:
(1) cleaned by Radix Bupleuri, water logging 6-8 hour (preferred water logging 7 hours), pulls out, section, gets Mel, and the weight of Mel is the weight of the preferred Mel of 1/5-1/3(of Radix Bupleuri weight is 1/4 of Radix Bupleuri weight), old honey is smelt with slow fire, tableted Radix Bupleuri is poured into, fries 14-26 minute (preferably frying 20 minutes), take the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, cross No. five sieves;
(2) get Fructus Mume, clean, add 8-11 times of water gaging (preferably adding 9 times of water gagings), soak 25 minutes, decoct 32-56 minute (preferably decocting 48 minutes), filter and remove residue, medicinal liquid is for subsequent use;
(3) get Bulbus Lilii, soak 12 hours, drop goes out moisture, put into soy bean milk making machine, add water, the consumption of water is 10-13 times (consumption of preferred water is 11 times of Bulbus Lilii weight) of Bulbus Lilii weight, select Five-grain soybean milk pattern, beat 12-18 minute (preferably making a call to 16 minutes), must starch for subsequent use;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 5.4-7.4 times (preferred amount of water is 6.6 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) step (2), step (3) and step (4) gained are mixed, leave standstill 10 hours, get upper liquid, be condensed into the ointment (being preferably condensed into the ointment that relative density is 1.3) that relative density is 1.28-1.32, add step (1) gained fine powder, mix well, add refined honey, every 100kg ointment adds the preferred every 100kg ointment of refined honey 134-150kg(and adds refined honey 142kg), micro-refining, foam removal, seals and get final product in dress aseptic bottle.
7. the preparation of the improvement night sweat symptom as described in as arbitrary in claims 1 to 3, it is characterized in that, the preparation of this improvement night sweat symptom is made pharmaceutically acceptable granule, and the preparation method of described granule is:
(1) cleaned by Radix Bupleuri, water logging 6-8 hour (preferred water logging 7 hours), pulls out, section, gets Mel, and the weight of Mel is the weight of the preferred Mel of 1/5-1/3(of Radix Bupleuri weight is 1/4 of Radix Bupleuri weight), old honey is smelt with slow fire, tableted Radix Bupleuri is poured into, fries 14-26 minute (preferably frying 20 minutes), take the dish out of the pot, spread out, dry in the air cool, be ground into fine powder, cross No. five sieves;
(2) get Fructus Mume, clean, add 8-11 times of water gaging (preferably adding 9 times of water gagings), soak 25 minutes, decoct 32-56 minute (preferably decocting 48 minutes), filter and remove residue, medicinal liquid is for subsequent use;
(3) Bulbus Lilii is got, soak 12 hours, drop goes out moisture, put into soy bean milk making machine, add water, the consumption of water is 10-13 times (consumption of preferred water is 11 times of Bulbus Lilii weight) of Bulbus Lilii weight, select Five-grain soybean milk pattern, beat 12-18 minute (preferably making a call to 16 minutes), by standing for gained serosity 3 hours, it was for subsequent use to get upper liquid;
(4) 12 taste crude drug except Radix Bupleuri, Fructus Mume and Bulbus Lilii are decocted with water twice, amount of water is 5.4-7.4 times (preferred amount of water is 6.6 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, and each decoction 35 minutes, merges twice medicinal liquid;
(5) by step (2) and the mixing of step (4) gained, be condensed into the ointment (being preferably condensed into the ointment that relative density is 1.3) that relative density is 1.28-1.32, dry, pulverize into fine powder, cross No. five sieves;
(6) by step (1) and the mixing of step (5) gained, add step (3) gained and make soft material, 16-20 mesh sieve is granulated (preferably granulating on 18 mesh sieves), and make uniform granule, drying, granulate, sub-sieve, to obtain final product.
8. improve the preparation method of the preparation decoction of night sweat symptom as claimed in claim 4, it is characterized in that, water logging 7 hours in step (1).
9. improve the preparation method of the preparation decoction of night sweat symptom as claimed in claim 4, it is characterized in that, in step (1), the weight of Mel is 1/4 of Radix Bupleuri weight.
10. improve the preparation method of the preparation decoction of night sweat symptom as claimed in claim 4, it is characterized in that, fry 20 minutes in step (1).
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| CN105535623A (en) * | 2016-01-15 | 2016-05-04 | 夏放军 | Traditional Chinese medicine pills for treating night sweat and preparation method thereof |
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| US20080057161A1 (en) * | 2003-08-05 | 2008-03-06 | Donald Brucker | Functionalized coffee |
| CN102836267A (en) * | 2011-06-23 | 2012-12-26 | 孙逊 | Traditional Chinese drug oral liquid for treating children night sweat |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20080057161A1 (en) * | 2003-08-05 | 2008-03-06 | Donald Brucker | Functionalized coffee |
| CN102836267A (en) * | 2011-06-23 | 2012-12-26 | 孙逊 | Traditional Chinese drug oral liquid for treating children night sweat |
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| CN105535623A (en) * | 2016-01-15 | 2016-05-04 | 夏放军 | Traditional Chinese medicine pills for treating night sweat and preparation method thereof |
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Address after: 756000 the Ningxia Hui Autonomous Region Yuanzhou District of Guyuan City Beihuan Limin District 2 Building 3 unit 601 Applicant after: Zhang Shiyuan Address before: 250000 Shandong, Ji'nan Flyover District Road, Tuen Mun, No. 12 Applicant before: Zhang Shiyuan |
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Application publication date: 20160113 |