CN102988870A - Oral liquid for treating diseases of liver, gall, stomach and intestinal canal - Google Patents

Oral liquid for treating diseases of liver, gall, stomach and intestinal canal Download PDF

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CN102988870A
CN102988870A CN2012105047575A CN201210504757A CN102988870A CN 102988870 A CN102988870 A CN 102988870A CN 2012105047575 A CN2012105047575 A CN 2012105047575A CN 201210504757 A CN201210504757 A CN 201210504757A CN 102988870 A CN102988870 A CN 102988870A
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parts
radix
fructus
rhizoma
root
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陈光明
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Beijing Zhongrong Yangguang Investment Management Co Ltd
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Beijing Zhongrong Yangguang Investment Management Co Ltd
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Abstract

The invention relates to oral liquid for treating diseases of the liver, gall, stomach and intestinal canal. The oral liquid comprises the following medicaments in parts by weight: 5 to 10 parts of pilose asiabell root, 5 to 10 parts of largehead atractylodes rhizome, 5 to 10 parts of astragalus mongholicus, 5 to 10 parts of common yam rhizome, 5 to 10 parts of northern hawthorn fruit, 5 to 10 parts of malt, 5 to 10 parts of tangerine peel, 5 to 10 parts of Chinese angelica, 5 to 10 parts of red sage root, 5 to 10 parts of bletilla striata, 5 to 10 parts of white paeony root, 5 to 10 parts of endothelium corneum gigeriae galli, 2 to 5 parts of liquoric root, 2 to 5 parts of Indian buead, 2 to 5 parts of finger citron, 2 to 5 parts of villous amomum fruit, 2 to 5 parts of officinal magnolia bark, 2 to 5 parts of Chinese eaglewood, 2 to 5 parts of cyperus rotundus, 2 to 5 parts of medlar, 2 to 5 parts of shelled cuttlebone, 2 to 5 parts of Chinese thorowax root, 2 to 5 parts of coastal glehnia root, 2 to 5 parts of fragrant solomonseal rhizome, 2 to 5 parts of Chinese magnoliavine fruit, 2 to 5 parts of shelled radish seed, 2 to 5 parts of white hyacinth bean, 2 to 5 parts of immature bitter orange, 2 to 5 parts of costustoot, 2 to 5 parts of coix seed and 2 to 5 parts of lindera root. The oral liquid is clinically proven to have a definite treatment effect on acute or chronic gastroenteritis.

Description

A kind of oral liquid for the treatment of the liver and gall gastroenteropathy
Technical field
The present invention relates to a kind of medicine for the treatment of the liver and gall gastroenteropathy and preparation method thereof, be specifically related to a kind of Chinese medicine oral liquid and preparation method thereof.
Background technology
Gastroenteropathy such as chronic gastritis, gastric ulcer, chronic colitis, gastrointestinal dysfunctions etc. are common clinically frequently-occurring diseases, wherein anorexia, belch, abdominal distention, diarrhoea, the syndrome such as weak appear in chronic gastritis, enteritis and gastrointestinal dysfunction, Western medicine just carries out part alleviation or treatment to gastroenteropathy, can't solve the problem of recurrence and side effect.
Summary of the invention
Technical problem to be solved by this invention provides a kind of Chinese medicine composition for the treatment of the liver and gall gastroenteropathy.
In order to address the above problem, the invention provides following technical proposals:
The present invention relates to a kind of Chinese medicine composition, contain following weight portion medicine: Radix Codonopsis 5-10 part, Rhizoma Atractylodis Macrocephalae 5-10 part, Radix Astragali 5-10 part, Rhizoma Dioscoreae 5-10 part, Fructus Crataegi 5-10 part, Fructus Hordei Germinatus 5-10 part, Pericarpium Citri Reticulatae 5-10 part, Radix Angelicae Sinensis 5-10 part, Radix Salviae Miltiorrhizae 5-10 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-10 part, Radix Paeoniae Alba 5-10 part, Endothelium Corneum Gigeriae Galli 5-10 part, Radix Glycyrrhizae 2-5 part, Poria 2-5 part, Fructus Citri Sarcodactylis 2-5 part, Fructus Amomi 2-5 part, Cortex Magnoliae Officinalis 2-5 part, Lignum Aquilariae Resinatum 2-5 part, Rhizoma Cyperi 2-5 part, Fructus Lycii 2-5 part, the Endoconcha Sepiae 2-5 part of shelling, Radix Bupleuri 2-5 part, Radix Glehniae 2-5 part, Rhizoma Polygonati Odorati 2-5 part, Fructus Schisandrae Chinensis 2-5 part, peeling Semen Raphani 2-5 part, Semen Lablab Album 2-5 part, Fructus Aurantii Immaturus 2-5 part, Radix Aucklandiae 2-5 part, Semen Coicis 2-5 part, root of three-nerved spicebush 2-5 part.Be preferably 5 parts of Radix Codonopsis, 5 parts of the Rhizoma Atractylodis Macrocephalaes, 5 parts of the Radixs Astragali, 5 parts of Rhizoma Dioscoreaes, 5 parts of Fructus Crataegis, 5 parts in Fructus Hordei Germinatus, 5 parts of Pericarpium Citri Reticulataes, 5 parts of Radix Angelicae Sinensis, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 5 parts of the Radix Paeoniae Albas, 5 parts of Endothelium Corneum Gigeriae Galli, 2 parts in Radix Glycyrrhizae, 3 parts in Poria, 2 parts of Fructus Citri Sarcodactylis, 3 parts of Fructus Amomis, 2 parts of Cortex Magnoliae Officinalis, 2 parts of Lignum Aquilariae Resinatum, 3 parts of Rhizoma Cyperi, 3 parts of Fructus Lyciis, 3 parts of the Endoconcha Sepiaes of shelling, 2 parts of Radix Bupleuri, 3 parts of Radix Glehniaes, 2 parts of Rhizoma Polygonati Odorati, 2 parts of Fructus Schisandrae Chinensis, 3 parts of peeling Semen Raphanis, 3 parts of Semen Lablab Albums, 3 parts of Fructus Aurantii Immaturuss, 3 parts of the Radix Aucklandiae, 3 parts of Semen Coiciss, 2 parts of the root of three-nerved spicebushs.
Get Radix Codonopsis 5-10g, Rhizoma Atractylodis Macrocephalae 5-10g, Radix Astragali 5-10g, Rhizoma Dioscoreae 5-10g, Fructus Crataegi 5-10g, Fructus Hordei Germinatus 5-10g, Pericarpium Citri Reticulatae 5-10g, Radix Angelicae Sinensis 5-10g, Radix Salviae Miltiorrhizae 5-10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-10g, Radix Paeoniae Alba 5-10g, Endothelium Corneum Gigeriae Galli 5-10g, Radix Glycyrrhizae 2-5g, Poria 2-5g, Fructus Citri Sarcodactylis 2-5g, Fructus Amomi 2-5g, Cortex Magnoliae Officinalis 2-5g, Lignum Aquilariae Resinatum 2-5g, Rhizoma Cyperi 2-5g, Fructus Lycii 2-5g, the Endoconcha Sepiae 2-5g that shells, Radix Bupleuri 2-5g, Radix Glehniae 2-5g, Rhizoma Polygonati Odorati 2-5g, Fructus Schisandrae Chinensis 2-5g, peeling Semen Raphani 2-5g, Semen Lablab Album 2-5g, Fructus Aurantii Immaturus 2-5g, Radix Aucklandiae 2-5g, Semen Coicis 2-5g, root of three-nerved spicebush 2-5g makes 1000ml.Be preferably and get Radix Codonopsis 5g, Rhizoma Atractylodis Macrocephalae 5g, Radix Astragali 5g, Rhizoma Dioscoreae 5g, Fructus Crataegi 5g, Fructus Hordei Germinatus 5g, Pericarpium Citri Reticulatae 5g, Radix Angelicae Sinensis 5g, Radix Salviae Miltiorrhizae 5g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Paeoniae Alba 5g, Endothelium Corneum Gigeriae Galli 5g, Radix Glycyrrhizae 2g, Poria 3g, Fructus Citri Sarcodactylis 2g, Fructus Amomi 3g, Cortex Magnoliae Officinalis 2g, Lignum Aquilariae Resinatum 2g, Rhizoma Cyperi 3g, Fructus Lycii 3g, the Endoconcha Sepiae 3g that shells, Radix Bupleuri 2g, Radix Glehniae 3g, Rhizoma Polygonati Odorati 2g, Fructus Schisandrae Chinensis 2g, peeling Semen Raphani 3g, Semen Lablab Album 3g, Fructus Aurantii Immaturus 3g, Radix Aucklandiae 3g, Semen Coicis 3g, root of three-nerved spicebush 2g makes 1000ml.
Manufacture method:
(1) gets Radix Codonopsis 5-10g, Rhizoma Atractylodis Macrocephalae 5-10g, Radix Astragali 5-10g, Rhizoma Dioscoreae 5-10g, Fructus Crataegi 5-10g, Fructus Hordei Germinatus 5-10g, Pericarpium Citri Reticulatae 5-10g, Radix Angelicae Sinensis 5-10g, Radix Salviae Miltiorrhizae 5-10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-10g, Radix Paeoniae Alba 5-10g, Endothelium Corneum Gigeriae Galli 5-10g, Radix Glycyrrhizae 2-5g, Poria 2-5g, Fructus Citri Sarcodactylis 2-5g, Fructus Amomi 2-5g, Cortex Magnoliae Officinalis 2-5g, Lignum Aquilariae Resinatum 2-5g, Rhizoma Cyperi 2-5g, Fructus Lycii 2-5g, the Endoconcha Sepiae 2-5g that shells, Radix Bupleuri 2-5g, Radix Glehniae 2-5g, Rhizoma Polygonati Odorati 2-5g, Fructus Schisandrae Chinensis 2-5g, peeling Semen Raphani 2-5g, Semen Lablab Album 2-5g, Fructus Aurantii Immaturus 2-5g, Radix Aucklandiae 2-5g, Semen Coicis 2-5g, root of three-nerved spicebush 2-5g decocts with water, filter, get filtrate, for subsequent use;
(2) step (1) filtering residue decocts with water 1-2 time, filters, and gets filtrate, and is for subsequent use;
(3) step (1) and step (2) filtrate merge, and heating is concentrated, gets concentrated solution;
(4) step (3) concentrated solution adds cereuisiae fermentum, Bulgarian Lactobacillus and acetobacter, ferments;
(5) step (4) filtering fermentation liquor is got filtrate, adds water and makes 1000ml, and get final product.
Step (1) and the described amount of water of step (2) are 5-10 times of medical material weight, and step (1) decocting time is 15-60 minute, and step (2) decocting time is 2-4 hour.
The amount of the described concentrated solution of step (3) is 5-7 times (w/w) of medical material weight.
The strain of step (4) institute selection-breeding derives from Hua Zhong Agriculture University, Hubei Province's edible fungi association, and strain quality requires first can guarantee that the every ml of relative density reaches 1 * 10 8Individual (more than 100,000,000), purity 100%, without living contaminants, the second strain safety in utilization is through the health ministry virulence test, Hubei Province Disease Control and Prevention Center toxicological test, result of the test meets the quality safety requirement, and excellent the going down to posterity of the 3rd strain training was no more than for the 5th generation, kept original fine quality and characteristic.Inoculum concentration is according to amount of fermentation, and step (3) concentrated solution mixes probiotic bacteria strain weight ratio with three kinds be 15-20:1, preferred 18:1.
Above-mentioned prescription foundation:
Radix Codonopsis nature and flavor: sweet, flat.Effect: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.Be used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
Rhizoma Atractylodis Macrocephalae nature and flavor: bitter, sweet, temperature.Effect: invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.Be used for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Radix Astragali nature and flavor: sweet, temperature.Effect: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst for a long time and do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Rhizoma Dioscoreae nature and flavor: sweet, flat.Effect: spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Be used for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.Be used for insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, leukorrhagia.
The Fructus Crataegi nature and flavor: sour, sweet, tepor.Effect: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.Be used for meat stagnation, gastral cavilty distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.
Fructus Hordei Germinatus nature and flavor: sweet, flat.Effect: spleen benefiting and stimulating the appetite, move back newborn relieving distension.Be used for food stagnation and do not disappear, women's ablactation.The Fructus Hordei Germinatus (parched to brown) relieving dyspepsia.Be used for food stagnation and do not disappear abdominal distention.
The Pericarpium Citri Reticulatae nature and flavor: bitter, hot, temperature.Effect: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Be used for fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
The Radix Angelicae Sinensis nature and flavor: sweet, hot, temperature.Effect: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.The Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.Be used for the amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
The Radix Salviae Miltiorrhizae nature and flavor: hardship is slightly cold.Effect: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Be used for menoxenia, amenorrhea dysmenorrhea , lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Pseudobulbus Bletillae (Rhizoma Bletillae) nature and flavor: bitter, sweet, puckery, be slightly cold.Effect: astringing to arrest bleeding, detumescence and promoting granulation.Be used for spitting of blood and spit blood traumatic hemorrhage, sore swollen toxin, chapped skin; Hemoptysis of pulmonary tuberculosis, ulcer haemorrhage.
Radix Paeoniae Alba nature and flavor: bitter, sour, be slightly cold.Effect: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.It is dizzy to be used for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Endothelium Corneum Gigeriae Galli nature and flavor: sweet, flat.Effect: invigorating the stomach and promoting digestion, arresting seminal emission.Be used for food stagnation and do not disappear, vomiting dysentery, infantile malnutrition, the enuresis, seminal emission.
Radix Glycyrrhizae nature and flavor: sweet, flat.Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Poria nature and flavor: sweet, light, flat.Effect: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.Be used for the edema oliguria, the phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in the loose stool, irritability, palpitation with fear insomnia.
The Fructus Citri Sarcodactylis nature and flavor: hot, bitter, sour, temperature.Effect: liver-smoothing, qi-regulating, and stomach and alleviating pain.Be used for stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, lack of appetite vomiting.
Fructus Amomi nature and flavor: suffering, temperature.Effect: the removing dampness appetizing, warming spleen and stopping diarrha, it is antiabortive to regulate the flow of vital energy.Be used for turbid damp obstructing in middle-JIAO, the gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.
The Cortex Magnoliae Officinalis nature and flavor: bitter, hot, temperature.Effect: the dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full.Be used for the humidity hysteresis damaging the spleen and stomach, the gastral cavity painful abdominal mass is vomited and diarrhoea, stagnation of QI due to dyspepsia, and abdominal distention constipation, phlegm retention is breathed with cough.
The Lignum Aquilariae Resinatum nature and flavor: hot, bitter, tepor.Effect: promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting, helping inspiration to relieve asthma.Be used for the vexed pain of breast abdominal distention, gastrofrigid vomiting singultus, the QI rising in reverse order of suffering from a deficiency of the kidney dyspnea with rapid respiration.
The Rhizoma Cyperi nature and flavor: hot, little hardship, little sweet, flat.Effect: promoting QI circulation for relieving depression, menstruction regulating and pain relieving.Be used for stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Fructus Lycii nature and flavor: sweet, flat.Effect: nourishing the liver and kidney, replenishing vital essence to improve eyesight.Cure mainly: be used for the asthenia damage of essence.Soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.
The Endoconcha Sepiae nature and flavor shell: salty, puckery, and temperature.Effect: astringing to arrest bleeding, relieving leukorrhea by astringents, antacid, sore.Be used for the stomachache acid regurgitation, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge; Peptic Ulcers.The external treatment bleeding due to trauma, the many pus of skin ulcer.
The Radix Bupleuri nature and flavor: hardship is slightly cold.Effect: reconciling superficies and interior, soothing the liver, yang invigorating.Be used for cold, fever. alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia; Uterine prolapse, proctoptosis.
The Radix Glehniae nature and flavor: sweet, little hardship is slightly cold.Effect: nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.Be used for lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound is thirsty.
The Rhizoma Polygonati Odorati nature and flavor: sweet, be slightly cold.Effect: nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.Be used for the lung stomach-Yin and hinder, cough caused by dryness-heat is swallowed in thirsty, and interior-heat is quenched one's thirst.
The Fructus Schisandrae Chinensis nature and flavor: sour, sweet, temperature.Effect: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Be used for the chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Peeling Semen Raphani nature and flavor: hot, sweet, flat.Effect: help digestion except swollen lowering the adverse-rising QI to resolve phlegm.Be used for retention of food and drink, abdominal distention, constipation, stagnant dysentery, the expectorant heap soil or fertilizer over and around the roots is breathed with cough.
The Semen Lablab Album nature and flavor: sweet, tepor.Effect: invigorating the spleen for eliminating dampness, and in relieve summer heat.Be used for weakness of the spleen and stomach, inappetence, diarrhea, leukorrhagia, heat-damp in summer is vomited and diarrhoea, abdominal distention uncomfortable in chest.The Semen Lablab Album (parched) invigorating the spleen for eliminating dampness.Be used for diarrhea due to hypofunction of the spleen, leukorrhagia.
The Fructus Aurantii Immaturus nature and flavor: bitter, hot, sour, temperature.Effect: dispelling the stagnated QI removing food stagnancy, the loose painful abdominal mass of reducing phlegm.Be used for stopping in stagnant, the feeling of fullness distending pain, heavy behind the dysentery, constipation, the expectorant vapour lock thoracic obstruction that stagnates, blocked-up chest; Gastroptosis, proctoptosis, uterine prolapse.
Radix Aucklandiae nature and flavor: hot, bitter, temperature.Effect: promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.Be used for breast gastral cavity distending pain, heavy behind the dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).Be used for having loose bowels stomachache.
Semen Coicis nature and flavor: sweet, light.Cool.Effect: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, clearing away heat and discharging pus.Be used for edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, pain in the lung, intestinal carbuncle; Verruca plana.
Root of three-nerved spicebush nature and flavor: hot, warm.Effect: pleasant pain relieving, warming kidney for dispelling cold.Cure mainly: be used for chest and abdomen swelling and pain, QI rising in reverse order dyspnea with rapid respiration, deficiency-cold in the urinary bladder, enuresis frequent micturition, hernia, dysmenorrhea.
We are monarch drug with the Chinese medicine of invigorating the spleen and replenishing QI, depressed liver-energy dispersing and QI regulating, the Chinese medicine of joining damp eliminating spleen invigorating, promoting digestion and removing stagnation stomach invigorating is ministerial drug, take add YIN nourishing and the production of body fluid promoting, the Chinese medicine of invigorating blood circulation, stopping blooding of enriching blood is as adjuvant drug, to add the antibacterial and detoxicating antiinflammatory, to be in harmonious proportion the Chinese medicine of the property of medicine for making medicine, its principles of formulating prescriptions are the methods of mediation of mending with disappearing, academic theory of the traditional Chinese medical science of inheriting well-known doctor king of medicine Pang Anshi in the Northern Song Dynasty be basic: " pent-up of liver fearness is when to regulate the flow of vital energy as elder generation; Stomach is afraid of that typhoid fever gets ill from overeating, when take intestinal stasis relieving eliminate indigestion, invigorating the spleen and replenishing QI as first; Spleen is afraid of wet being stranded, and is good for fortune as first when wetting take Eradicates ", we are by " decoction of four noble drugs "; " Xiangsha Liujunzi decoction ", " Radix Ginseng atractylodes decoction ", " GUIPI TANG "; the compound recipe that plus-minuss such as " XIAOYAO POWDER " is combined into by using the modern biotechnology preparation, have unique curative effect to treating the liver and gall gastrointestinal disease.
Through clinical verification, above-mentioned oral liquid has definite curative effect to chronic gastritis and chronic enteritis.
The specific embodiment
Illustrate in greater detail the present invention below in conjunction with embodiment, but the present invention is not subjected to any restriction of these records.
Embodiment 1
Radix Codonopsis 5g, Rhizoma Atractylodis Macrocephalae 5g, Radix Astragali 5g, Rhizoma Dioscoreae 5g, Fructus Crataegi 5g, Fructus Hordei Germinatus 5g, Pericarpium Citri Reticulatae 5g, Radix Angelicae Sinensis 5g, Radix Salviae Miltiorrhizae 5g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Paeoniae Alba 5g, Endothelium Corneum Gigeriae Galli 5g, Radix Glycyrrhizae 2g, Poria 3g, Fructus Citri Sarcodactylis 2g, Fructus Amomi 3g, Cortex Magnoliae Officinalis 2g, Lignum Aquilariae Resinatum 2g, Rhizoma Cyperi 3g, Fructus Lycii 3g, Endoconcha Sepiae 3g shells, Radix Bupleuri 2g, Radix Glehniae 3g, Rhizoma Polygonati Odorati 2g, Fructus Schisandrae Chinensis 2g, peeling Semen Raphani 3g, Semen Lablab Album 3g, Fructus Aurantii Immaturus 3g, Radix Aucklandiae 3g, Semen Coicis 3g, root of three-nerved spicebush 2g.
Manufacture method:
(1) gets above-mentioned medical material, add 10 times of water gagings, soaked 3 hours;
(2) heated and boiled is 15 minutes, filters, and gets filtrate, and is for subsequent use;
(3) filtering residue adds 5 times of water gagings, and heated and boiled 3 hours is filtered, and gets filtrate, and is for subsequent use;
(4) step (2) and step (3) filtrate merge, and heating is concentrated into 7 times of medical material weight, gets concentrated solution;
(5) step (4) concentrated solution adds cereuisiae fermentum, Bulgarian Lactobacillus and acetobacter, and it is 15:1 that concentrated solution mixes probiotic bacteria strain weight ratio with three kinds, ferments;
(6) step (5) filtering fermentation liquor is got filtrate, adds water and makes 1000ml, and get final product.
Embodiment 2
Radix Codonopsis 10g, Rhizoma Atractylodis Macrocephalae 10g, Radix Astragali 10g, Rhizoma Dioscoreae 10g, Fructus Crataegi 10g, Fructus Hordei Germinatus 10g, Pericarpium Citri Reticulatae 10g, Radix Angelicae Sinensis 10g, Radix Salviae Miltiorrhizae 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 10g, Radix Paeoniae Alba 10g, Endothelium Corneum Gigeriae Galli 10g, Radix Glycyrrhizae 2g, Poria 2g, Fructus Citri Sarcodactylis 2g, Fructus Amomi 2g, Cortex Magnoliae Officinalis 2g, Lignum Aquilariae Resinatum 2g, Rhizoma Cyperi 2g, Fructus Lycii 2g, Endoconcha Sepiae 2g shells, Radix Bupleuri 2g, Radix Glehniae 2g, Rhizoma Polygonati Odorati 2g, Fructus Schisandrae Chinensis 2g, peeling Semen Raphani 2g, Semen Lablab Album 2g, Fructus Aurantii Immaturus 2g, Radix Aucklandiae 2g, Semen Coicis 2g, root of three-nerved spicebush 2g.
Manufacture method:
(1) gets above-mentioned medical material, add 5 times of water gagings, soaked 3 hours;
(2) heated and boiled is 60 minutes, filters, and gets filtrate, and is for subsequent use;
(3) filtering residue adds 5 times of water gagings, and heated and boiled 4 hours is filtered, and gets filtrate, and is for subsequent use;
(4) step (2) and step (3) filtrate merge, and heating is concentrated into 5 times of medical material weight, gets concentrated solution;
(5) step (4) concentrated solution adds cereuisiae fermentum, Bulgarian Lactobacillus and acetobacter, and it is 20:1 that concentrated solution mixes probiotic bacteria strain weight ratio with three kinds, ferments;
(6) step (5) filtering fermentation liquor is got filtrate, adds water and makes 1000ml, and get final product.
Embodiment 3
Radix Codonopsis 5g, Rhizoma Atractylodis Macrocephalae 5g, Radix Astragali 5g, Rhizoma Dioscoreae 5g, Fructus Crataegi 5g, Fructus Hordei Germinatus 5g, Pericarpium Citri Reticulatae 5g, Radix Angelicae Sinensis 5g, Radix Salviae Miltiorrhizae 5g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Paeoniae Alba 5g, Endothelium Corneum Gigeriae Galli 5g, Radix Glycyrrhizae 5g, Poria 5g, Fructus Citri Sarcodactylis 5g, Fructus Amomi 5g, Cortex Magnoliae Officinalis 5g, Lignum Aquilariae Resinatum 5g, Rhizoma Cyperi 5g, Fructus Lycii 5g, Endoconcha Sepiae 5g shells, Radix Bupleuri 5g, Radix Glehniae 5g, Rhizoma Polygonati Odorati 5g, Fructus Schisandrae Chinensis 5g, peeling Semen Raphani 5g, Semen Lablab Album 5g, Fructus Aurantii Immaturus 5g, Radix Aucklandiae 5g, Semen Coicis 5g, root of three-nerved spicebush 5g.
Manufacture method:
(1) gets above-mentioned medical material, add 10 times of water gagings, soaked 3 hours;
(2) heated and boiled is 30 minutes, filters, and gets filtrate, and is for subsequent use;
(3) filtering residue adds 10 times of water gagings, and heated and boiled 2 hours is filtered, and gets filtrate, and is for subsequent use;
(4) step (2) and step (3) filtrate merge, and heating is concentrated into 5 times of medical material weight, gets concentrated solution;
(5) step (4) concentrated solution adds cereuisiae fermentum, Bulgarian Lactobacillus and acetobacter, and it is 18:1 that concentrated solution mixes probiotic bacteria strain weight ratio with three grades, ferments;
(6) step (5) filtering fermentation liquor is got filtrate, adds water and makes 1000ml, and get final product.
Embodiment 4 clinical observations
1, physical data
20 ~ 70 years old object of observation age of including in, average 47 years old.Male 120 people, women 156 people.The object of observation is all done health check-up, all without serious organ disease.
2, test case standard
Tcm diagnosis standard: have following clinical manifestation: epigastric distending pain, anorexia, abdominal distention, large loose stool is thin, limbs asthenia, lusterless complexion, acid regurgitation, red tongue, yellow fur.
Western medicine diagnose standard: relate to acute or chronic gastritis, acute chronic enteritis, the diseases such as gastrointestinal dysfunction.
3, administrated method
Make solution by embodiment 1, every day 2 times, each 200ml.Chronic gastritis patients having chronic intestinal inflammation 1-2 month course for the treatment of, one course for the treatment of of acute gastritis acute enteritis patient two weeks.
4, observational technique
Cardinal symptom: upper abdominal pain number of times, degree; Diarrhoea; Abdominal distention; Acid regurgitation.
Minor symptom: belch, feel sick loss of appetite, asthenia.
Safety: select some cases to carry out blood, urine, just routine test.
5, evaluation criterion
Recovery from illness: cardinal symptom and minor symptom are all eliminated.
Produce effects: cardinal symptom and minor symptom all have clear improvement.
Effectively: cardinal symptom and minor symptom all are improved.
Invalid: cardinal symptom and minor symptom are all without improving.
6, therapeutic outcome
? The example number Recovery from illness Produce effects Effectively Invalid Effective percentage (%)
Acute or chronic gastritis 127 32 46 37 12 90.6
Acute chronic enteritis 149 23 38 68 20 86.6

Claims (10)

1. a Chinese medicine composition is characterized in that, contains following weight portion medicine: Radix Codonopsis 5-10 part, Rhizoma Atractylodis Macrocephalae 5-10 part, Radix Astragali 5-10 part, Rhizoma Dioscoreae 5-10 part, Fructus Crataegi 5-10 part, Fructus Hordei Germinatus 5-10 part, Pericarpium Citri Reticulatae 5-10 part, Radix Angelicae Sinensis 5-10 part, Radix Salviae Miltiorrhizae 5-10 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-10 part, Radix Paeoniae Alba 5-10 part, Endothelium Corneum Gigeriae Galli 5-10 part, Radix Glycyrrhizae 2-5 part, Poria 2-5 part, Fructus Citri Sarcodactylis 2-5 part, Fructus Amomi 2-5 part, Cortex Magnoliae Officinalis 2-5 part, Lignum Aquilariae Resinatum 2-5 part, Rhizoma Cyperi 2-5 part, Fructus Lycii 2-5 part, the Endoconcha Sepiae 2-5 part of shelling, Radix Bupleuri 2-5 part, Radix Glehniae 2-5 part, Rhizoma Polygonati Odorati 2-5 part, Fructus Schisandrae Chinensis 2-5 part, peeling Semen Raphani 2-5 part, Semen Lablab Album 2-5 part, Fructus Aurantii Immaturus 2-5 part, Radix Aucklandiae 2-5 part, Semen Coicis 2-5 part, root of three-nerved spicebush 2-5 part.
2. Chinese medicine composition according to claim 1 is characterized in that, contains following weight portion medicine: 5 parts of Radix Codonopsis, 5 parts of the Rhizoma Atractylodis Macrocephalaes, 5 parts of the Radixs Astragali, 5 parts of Rhizoma Dioscoreaes, 5 parts of Fructus Crataegis, 5 parts in Fructus Hordei Germinatus, 5 parts of Pericarpium Citri Reticulataes, 5 parts of Radix Angelicae Sinensis, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 5 parts of the Radix Paeoniae Albas, 5 parts of Endothelium Corneum Gigeriae Galli, 2 parts in Radix Glycyrrhizae, 3 parts in Poria, 2 parts of Fructus Citri Sarcodactylis, 3 parts of Fructus Amomis, 2 parts of Cortex Magnoliae Officinalis, 2 parts of Lignum Aquilariae Resinatum, 3 parts of Rhizoma Cyperi, 3 parts of Fructus Lyciis, 3 parts of the Endoconcha Sepiaes of shelling, 2 parts of Radix Bupleuri, 3 parts of Radix Glehniaes, 2 parts of Rhizoma Polygonati Odorati, 2 parts of Fructus Schisandrae Chinensis, 3 parts of peeling Semen Raphanis, 3 parts of Semen Lablab Albums, 3 parts of Fructus Aurantii Immaturuss, 3 parts of the Radix Aucklandiae, 3 parts of Semen Coiciss, 2 parts of the root of three-nerved spicebushs.
3. Chinese medicine composition according to claim 1 is characterized in that, contains following medicine: Radix Codonopsis 5-10g, Rhizoma Atractylodis Macrocephalae 5-10g, Radix Astragali 5-10g, Rhizoma Dioscoreae 5-10g, Fructus Crataegi 5-10g, Fructus Hordei Germinatus 5-10g, Pericarpium Citri Reticulatae 5-10g, Radix Angelicae Sinensis 5-10g, Radix Salviae Miltiorrhizae 5-10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-10g, Radix Paeoniae Alba 5-10g, Endothelium Corneum Gigeriae Galli 5-10g, Radix Glycyrrhizae 2-5g, Poria 2-5g, Fructus Citri Sarcodactylis 2-5g, Fructus Amomi 2-5g, Cortex Magnoliae Officinalis 2-5g, Lignum Aquilariae Resinatum 2-5g, Rhizoma Cyperi 2-5g, Fructus Lycii 2-5g, the Endoconcha Sepiae 2-5g that shells, Radix Bupleuri 2-5g, Radix Glehniae 2-5g, Rhizoma Polygonati Odorati 2-5g, Fructus Schisandrae Chinensis 2-5g, peeling Semen Raphani 2-5g, Semen Lablab Album 2-5g, Fructus Aurantii Immaturus 2-5g, Radix Aucklandiae 2-5g, Semen Coicis 2-5g, root of three-nerved spicebush 2-5g makes 1000ml.
4. Chinese medicine composition according to claim 3 is characterized in that, contains following medicine: Radix Codonopsis 5g, Rhizoma Atractylodis Macrocephalae 5g, Radix Astragali 5g, Rhizoma Dioscoreae 5g, Fructus Crataegi 5g, Fructus Hordei Germinatus 5g, Pericarpium Citri Reticulatae 5g, Radix Angelicae Sinensis 5g, Radix Salviae Miltiorrhizae 5g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Paeoniae Alba 5g, Endothelium Corneum Gigeriae Galli 5g, Radix Glycyrrhizae 2g, Poria 3g, Fructus Citri Sarcodactylis 2g, Fructus Amomi 3g, Cortex Magnoliae Officinalis 2g, Lignum Aquilariae Resinatum 2g, Rhizoma Cyperi 3g, Fructus Lycii 3g, the Endoconcha Sepiae 3g that shells, Radix Bupleuri 2g, Radix Glehniae 3g, Rhizoma Polygonati Odorati 2g, Fructus Schisandrae Chinensis 2g, peeling Semen Raphani 3g, Semen Lablab Album 3g, Fructus Aurantii Immaturus 3g, Radix Aucklandiae 3g, Semen Coicis 3g, root of three-nerved spicebush 2g makes 1000ml.
5. the preparation method of a Chinese medicine composition claimed in claim 1 is characterized in that, may further comprise the steps:
(1) gets Radix Codonopsis 5-10g, Rhizoma Atractylodis Macrocephalae 5-10g, Radix Astragali 5-10g, Rhizoma Dioscoreae 5-10g, Fructus Crataegi 5-10g, Fructus Hordei Germinatus 5-10g, Pericarpium Citri Reticulatae 5-10g, Radix Angelicae Sinensis 5-10g, Radix Salviae Miltiorrhizae 5-10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-10g, Radix Paeoniae Alba 5-10g, Endothelium Corneum Gigeriae Galli 5-10g, Radix Glycyrrhizae 2-5g, Poria 2-5g, Fructus Citri Sarcodactylis 2-5g, Fructus Amomi 2-5g, Cortex Magnoliae Officinalis 2-5g, Lignum Aquilariae Resinatum 2-5g, Rhizoma Cyperi 2-5g, Fructus Lycii 2-5g, the Endoconcha Sepiae 2-5g that shells, Radix Bupleuri 2-5g, Radix Glehniae 2-5g, Rhizoma Polygonati Odorati 2-5g, Fructus Schisandrae Chinensis 2-5g, peeling Semen Raphani 2-5g, Semen Lablab Album 2-5g, Fructus Aurantii Immaturus 2-5g, Radix Aucklandiae 2-5g, Semen Coicis 2-5g, root of three-nerved spicebush 2-5g decocts with water, filter, get filtrate, for subsequent use;
(2) step (1) filtering residue decocts with water 1-2 time, filters, and gets filtrate, and is for subsequent use;
(3) step (1) and step (2) filtrate merge, and heating is concentrated, gets concentrated solution;
(4) step (3) concentrated solution adds cereuisiae fermentum, Bulgarian Lactobacillus and acetobacter, ferments;
(5) step (4) filtering fermentation liquor is got filtrate, adds water and makes 1000ml, and get final product.
6. the preparation method of Chinese medicine composition according to claim 5 is characterized in that, may further comprise the steps:
(1) gets Radix Codonopsis 5g, Rhizoma Atractylodis Macrocephalae 5g, Radix Astragali 5g, Rhizoma Dioscoreae 5g, Fructus Crataegi 5g, Fructus Hordei Germinatus 5g, Pericarpium Citri Reticulatae 5g, Radix Angelicae Sinensis 5g, Radix Salviae Miltiorrhizae 5g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Paeoniae Alba 5g, Endothelium Corneum Gigeriae Galli 5g, Radix Glycyrrhizae 2g, Poria 3g, Fructus Citri Sarcodactylis 2g, Fructus Amomi 3g, Cortex Magnoliae Officinalis 2g, Lignum Aquilariae Resinatum 2g, Rhizoma Cyperi 3g, Fructus Lycii 3g, the Endoconcha Sepiae 3g that shells, Radix Bupleuri 2g, Radix Glehniae 3g, Rhizoma Polygonati Odorati 2g, Fructus Schisandrae Chinensis 2g, peeling Semen Raphani 3g, Semen Lablab Album 3g, Fructus Aurantii Immaturus 3g, Radix Aucklandiae 3g, Semen Coicis 3g, root of three-nerved spicebush 2g decocts with water, and filters, and gets filtrate, and is for subsequent use;
(2) step (1) filtering residue decocts with water 1-2 time, filters, and gets filtrate, and is for subsequent use;
(3) step (1) and step (2) filtrate merge, and heating is concentrated, gets concentrated solution;
(4) step (3) concentrated solution adds cereuisiae fermentum, Bulgarian Lactobacillus and acetobacter, ferments;
(5) step (4) filtering fermentation liquor is got filtrate, adds water and makes 1000ml, and get final product.
7. the preparation method of Chinese medicine composition according to claim 5, it is characterized in that, step (1) and the described amount of water of step (2) are 5-10 times of medical material weight, and step (1) decocting time is 15-60 minute, and step (2) decocting time is 2-4 hour.
8. the preparation method of Chinese medicine composition according to claim 5 is characterized in that, the amount of the described concentrated solution of step (3) is 5-7 times (w/w) of medical material weight.
9. the preparation method of Chinese medicine composition according to claim 5 is characterized in that, the weight ratio of the described cereuisiae fermentum of step (4), Bulgarian Lactobacillus and acetobacter total amount and step (3) concentrated solution is 1:15-20.
10. the preparation method of Chinese medicine composition according to claim 9 is characterized in that, the weight ratio of the described cereuisiae fermentum of step (4), Bulgarian Lactobacillus and acetobacter total amount and step (3) concentrated solution is 1:18.
CN2012105047575A 2012-11-30 2012-11-30 Oral liquid for treating diseases of liver, gall, stomach and intestinal canal Pending CN102988870A (en)

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CN103393121A (en) * 2013-06-17 2013-11-20 湖北富程祥云生物科技有限公司 Preparation method of enzyme-containing compound probiotic plant ferment able to improve gastrointestinal functions
CN103599433A (en) * 2013-11-19 2014-02-26 太和县中医院 Traditional Chinese medicine for treating acute gastritis
CN103623171A (en) * 2013-11-15 2014-03-12 王芬 Traditional Chinese medicine composition for treating chronic gastritis
CN103638372A (en) * 2013-11-14 2014-03-19 谭晓明 Traditional Chinese medicine composition, preparation method and application thereof
CN103656043A (en) * 2013-12-13 2014-03-26 济南凯因生物科技有限公司 Traditional Chinese medicine with effects of relaxing bowels and lubricating intestines
CN103656222A (en) * 2013-12-25 2014-03-26 陕西步长高新制药有限公司 Chinese medicinal preparation for treating chronic gastritis and preparation method thereof
CN104013912A (en) * 2014-05-27 2014-09-03 李大波 Traditional Chinese medicine composition for treating chronic atrophic gastritis
WO2015149392A1 (en) * 2014-03-31 2015-10-08 袁志贤 Preparation of traditional chinese medicine for treating chronic colitis and preparation method therefor
CN107080776A (en) * 2017-03-17 2017-08-22 广州华农大实验兽药有限公司 Improve traditional Chinese medicine oral liquid of livestock and poultry anti-stress ability and preparation method and application
CN109198630A (en) * 2018-10-25 2019-01-15 厦门三宝地网络科技有限公司 Fat health food of a kind of increasing flesh increasing and preparation method thereof
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CN103393121A (en) * 2013-06-17 2013-11-20 湖北富程祥云生物科技有限公司 Preparation method of enzyme-containing compound probiotic plant ferment able to improve gastrointestinal functions
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CN103638372B (en) * 2013-11-14 2016-01-20 谭晓明 A kind of Chinese medicine composition and its preparation method and application
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WO2015149392A1 (en) * 2014-03-31 2015-10-08 袁志贤 Preparation of traditional chinese medicine for treating chronic colitis and preparation method therefor
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CN107080776A (en) * 2017-03-17 2017-08-22 广州华农大实验兽药有限公司 Improve traditional Chinese medicine oral liquid of livestock and poultry anti-stress ability and preparation method and application
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