CN104013912A - Traditional Chinese medicine composition for treating chronic atrophic gastritis - Google Patents

Traditional Chinese medicine composition for treating chronic atrophic gastritis Download PDF

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CN104013912A
CN104013912A CN201410229678.7A CN201410229678A CN104013912A CN 104013912 A CN104013912 A CN 104013912A CN 201410229678 A CN201410229678 A CN 201410229678A CN 104013912 A CN104013912 A CN 104013912A
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chinese medicine
atrophic gastritis
medicine composition
radix
chronic atrophic
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张自英
李大波
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Abstract

The invention discloses a traditional Chinese medicine composition for treating chronic atrophic gastritis, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition helps to solve the persistent and incurable problems of chronic atrophic gastritis. The traditional Chinese medicine composition is composed of the following raw materials by weight: 8-12 g of radix et rhizoma nardostachyos, 5-10 g of fructus phyllanthi, 3-8 g of rhizoma atractylodis macrocephalae, 3-8 g of poria cocos, 1-5 g of rhizoma curcumae, 3-8 g of radix aucklandiae, 8-12 g of fructus lycii, 5-10 g of semen cuscutae, 1-5 g of radix linderae, 5-10 g of lignum aquilariae resinatum, 5-10 g of hyacinth bean and 6-12 g of chicken's gizzard membrane. The traditional Chinese medicine composition is administrable for patients attacked by chronic atrophic gastritis, the cure rate is 84% and the effective rate is 91%.

Description

The Chinese medicine composition for the treatment of chronic atrophic gastritis
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis, belong to the field of Chinese medicines.
Background technology
Chronic atrophic gastritis, belongs to the traditional Chinese medical science " gastric abscess ", and the category of " abdominal distention ", is a kind of commonly encountered diseases, and World Health Organization (WHO) is classified as Gastric precancerous condition, and especially with intestinal epithelial metaplasia or atypical hyperplasia person, canceration probability is larger.Slowly, patient's condition is touching in its morbidity, and delay is difficult, treat thorny, therefore the taste academic conference for the third time of the national association of traditional Chinese medicine think that chronic atrophic gastritis is dialectical and can belong to " stomach painful abdominal mass " card, with regard to atrophic gastritis.The clinical manifestation of chronic atrophic gastritis not only lacks specificity, and also not quite identical with lesion degree, clinically, some Chronic Atrophic Gastritis Patients can non-evident sympton, but Most patients can have epigastrium causalgia, distending pain, dull pain or distension, painful abdominal mass is vexed, especially with after eating for very, inappetence, feels sick, belch, the symptom such as constipation or diarrhoea, severe patient can be become thin, anemia, onychorrhexis, glossitis or atrophy of tongue papillae, minority gastric mucosal erosion person can be with upper gastrointestinal hemorrhage.At present, the Therapeutic Method both at home and abroad primary disease being there is no.
Chronic atrophic gastritis, belongs to the categories such as the traditional Chinese medical science " feeling of fullness ", " gastric abscess ", " flatulence ", " noisy ", " indigestion and loss of appetite ".About the record of primary disease, first appeared in "Nei Jing", " interior through the hexa-atomic large opinion of just recording of Plain Questions " said: " strongly fragrant the sending out of wood, the sick epigastralgia right below the heart of the people, above props up two sides of body, and diaphragm pharynx is obstructed, aphagia." Zhang Zhongjing, Sun Simiao also have further discussion to primary disease; " gastric abscess " disease that calls for specialized treatment, specially square is found in " secret record of the orchid chamber " of gold dollar Lee in period Dong Yuan, and treatment chronic atrophic gastritis is played to directive function.Clear leaf sky scholar " Linzheng Zhinan Yi gastric abscess ", has many distinctive features for the Coryza Treated by Syndrome Differentiation of primary disease, points out: " husband's pain is obstructed, and negative and positive of qi and blood must be studied carefully in logical word, is to see essentials for diagnosis purport "; Add: " stomachache is sent out for a long time and repeatly must have solidifying expectorant to gather the stasis of blood." the saying of special proposition " pain enters network for a long time ".The sick position of chronic atrophic gastritis is at stomach, and what canvass should be at stomach film (stomach network), and all has substantial connection with the catharsis of liver, the lucid yang sending up of spleen, the turbid descending of stomach.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis, can effectively cure chronic atrophic gastritis, short treating period, instant effect.
The Chinese medicine composition of described treatment chronic atrophic gastritis, is made up of the raw material of Chinese medicine of following weight proportion: Radix Et Rhizoma Nardostachyos 8-12g, Fructus Phyllanthi 5-10g, Rhizoma Atractylodis Macrocephalae 3-8g, Poria 3-8g, Rhizoma Curcumae 1-5g, Radix Aucklandiae 3-8g, Fructus Lycii 8-12g, Semen Cuscutae 5-10g, Radix Linderae 1-5g, Lignum Aquilariae Resinatum 5-10g, Seem Lablab Album 5-10g, Endothelium Corneum Gigeriae Galli 6-12g.
Preferably, the Chinese medicine composition for the treatment of chronic atrophic gastritis, is made up of the raw material of Chinese medicine of following weight proportion: Radix Et Rhizoma Nardostachyos 10g, Fructus Phyllanthi 8g, Rhizoma Atractylodis Macrocephalae 5g, Poria 5g, Rhizoma Curcumae 3g, Radix Aucklandiae 5g, Fructus Lycii 10g, Semen Cuscutae 8g, Radix Linderae 3g, Lignum Aquilariae Resinatum 7g, Seem Lablab Album 8g, Endothelium Corneum Gigeriae Galli 9g.
The pharmacological action of each Chinese medicine:
Radix Et Rhizoma Nardostachyos: acrid, sweet, warm.Return spleen, stomach warp.Function with cure mainly: regulating QI to relieve pain, relieving stagnation and activating the spleen.For distension and fullness in the abdomen, inappetence, vomiting; External treatment toothache, swelling of the feet.
Fructus Phyllanthi: sweet, sour, puckery, cool.Function with cure mainly: clearing away heat and cooling blood, promoting digestion and invigorating the stomach, the cough-relieving of promoting the production of body fluid.For heat in blood blood stasis, liver-gallbladder disease, dyspepsia, stomachache, cough, laryngalgia, xerostomia.
The Rhizoma Atractylodis Macrocephalae: warm in nature, bitter in the mouth, sweet.Function cures mainly: invigorating the spleen and benefiting QI, and dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention have loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Poria: property is flat, sweet in the mouth, light.Function cures mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool have loose bowels, irritability, palpitation with fear insomnia.
Rhizoma Curcumae: pungent, bitter, temperature.Return liver, spleen channel.Function with cure mainly: circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Early cervical carcinoma.
The Radix Aucklandiae: bitter, micro-sweet, temperature; Poisonous.Return liver, spleen, stomach warp.Function with cure mainly: mass dissipating and swelling eliminating, counteracting toxic substances treat skin ulcer.For sore swollen toxin, acute mastitis, scrofula, anal fistula, chronic eczema, tinea alba.
Fructus Lycii: sweet, flat.Return liver, kidney channel.Function with cure mainly: nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.
Semen Cuscutae: warm in nature, sweet in the mouth.Function cures mainly: nourishing the liver and kidney, and controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.
The Radix Linderae: warm in nature, hide pungent.Function cures mainly: pleasant pain relieving, warming kidney for dispelling cold.For chest and abdomen swelling and pain, QI rising in reverse order dyspnea with rapid respiration, deficiency-cold in the urinary bladder, enuresis frequent micturition, hernia, dysmenorrhea.
Lignum Aquilariae Resinatum: slightly warm in nature, acrid in the mouth, hardship.Function cures mainly: promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting, helping inspiration to relieve asthma.For the vexed pain of breast abdominal distention, gastrofrigid vomiting singultus, the QI rising in reverse order of suffering from a deficiency of the kidney dyspnea with rapid respiration.
Seem Lablab Album: sweet in the mouth, property are flat, returns, stomach warp, have spleen invigorating and in, QI invigorating, removing dampness, the effect of relieving summer heat; Cure mainly insufficiency of the spleen holding concurrently and wet, anorexia and loose stool, turbid damp bet, women's leukorrhagia is too much, heat-damp in summer damaging the spleen and stomach, the convulsion of vomiting and diarrhoea waits card.
Endothelium Corneum Gigeriae Galli: sweet, flat.Return spleen, stomach, small intestinal, urinary bladder channel.Function with cure mainly: invigorating the stomach and promoting digestion, arresting seminal emission.Do not disappear for food stagnation, vomiting dysentery, infantile malnutrition, the enuresis, seminal emission.
Profitable effect of the present invention is:
The present invention adopts pure Chinese medicinal preparation, without any side effects, for the Deficiency and coldness of spleen and stomach, stagnation of liver-QI and stomach-QI, the qi depression to blood stasis that cause chronic atrophic gastritis, rational use of drug, scientific matching, each taste Chinese medicine synergism has the effect of tonifying-Yin and nourishing-stomach, depressed liver-energy dispersing and QI regulating, replenishing QI to invigorate the spleen, blood circulation promoting and blood stasis dispelling, by improving the circulation of gastric mucosa blood, effectively cure chronic atrophic gastritis, cure rate 84%, effective percentage 91%.
Below by clinical data and model case, the present invention will be further described.
Clinical trial
1, clinical data:
Randomly draw 200 of the medical Chronic Atrophic Gastritis Patients of coming between year December in May, 2007 to 2012, wherein each 100 of men and women; Age between 17-75 year, 56 years old mean age; The shortest course of disease 3 years, the longest 17 years, average 12.5 years.Clinical manifestation is that gastral cavilty feeling of fullness, gastralgia, belch, pantothenic acid, heartburn or burning sensation, upset in the stomach, fatigue and weak, diet (early full), stool change (rare half congealed, constipated).Diagnostic criteria is: the intrinsic body of gland of gastric mucosa (body of stomach fundic gland, pyloric gland and cardiac gland) atrophy or disappearance in various degree; Intestinal epithelial metaplasia or false gland metaplasia; Lamina propria diffusivity lymphocyte, plasmocyte infiltrating and lymph follicle form; Mucosa flesh thickens.
2, Therapeutic Method:
Get medicine of the present invention, be decocted in water for oral dose, every day potion, sooner or later each decoction is once taken.A month course for the treatment of, take medicine altogether 5 courses for the treatment of.
3, criterion of therapeutical effect:
Recovery from illness: clinical symptom disappearance, histopathologic examination confirm that body of gland atrophy, intestinal epithelial metaplasia and dysplasia recover normal or disappear.
Effective: main clinic symptoms disappears, gastroscope check mucosa chronic inflammatory disease takes a turn for the better, and histopathologic examination confirms that body of gland atrophy, intestinal epithelial metaplasia and dysplasia recover normal or alleviate.
Invalid: do not reach above-mentioned effective standard, or deterioration person.
4, therapeutic outcome:
200 Chronic Atrophic Gastritis Patients were taken medicine after 5 courses for the treatment of, 168 people's recoveries from illness, and 14 people are effective, and 18 people are invalid, cure rate 84%, effective percentage 91%.
Detailed description of the invention
Embodiment 1
The Chinese medicine composition of described treatment chronic atrophic gastritis, is made up of the raw material of Chinese medicine of following weight proportion: Radix Et Rhizoma Nardostachyos 10g, Fructus Phyllanthi 8g, Rhizoma Atractylodis Macrocephalae 5g, Poria 5g, Rhizoma Curcumae 3g, Radix Aucklandiae 5g, Fructus Lycii 10g, Semen Cuscutae 8g, Radix Linderae 3g, Lignum Aquilariae Resinatum 7g, Seem Lablab Album 8g, Endothelium Corneum Gigeriae Galli 9g.
Embodiment 2
Treat a Chinese medicine composition for chronic atrophic gastritis, formed by the raw material of Chinese medicine of following weight proportion: Radix Et Rhizoma Nardostachyos 8g, Fructus Phyllanthi 5g, Rhizoma Atractylodis Macrocephalae 3g, Poria 3g, Rhizoma Curcumae 1g, Radix Aucklandiae 3g, Fructus Lycii 8g, Semen Cuscutae 5g, Radix Linderae 1g, Lignum Aquilariae Resinatum 5g, Seem Lablab Album 5g, Endothelium Corneum Gigeriae Galli 6g.
Embodiment 3
A kind of Chinese medicine composition for the treatment of chronic atrophic gastritis, it is characterized in that, formed by the raw material of Chinese medicine of following weight proportion: Radix Et Rhizoma Nardostachyos 12g, Fructus Phyllanthi 10g, Rhizoma Atractylodis Macrocephalae 8g, Poria 8g, Rhizoma Curcumae 5g, Radix Aucklandiae 8g, Fructus Lycii 12g, Semen Cuscutae 10g, Radix Linderae 5g, Lignum Aquilariae Resinatum 10g, Seem Lablab Album 10g, Endothelium Corneum Gigeriae Galli 12g.
Embodiment 4
Treat a Chinese medicine composition for chronic atrophic gastritis, formed by the raw material of Chinese medicine of following weight proportion: Radix Et Rhizoma Nardostachyos 8-12g, Fructus Phyllanthi 7g, Rhizoma Atractylodis Macrocephalae 6g, Poria 4g, Rhizoma Curcumae 5g, Radix Aucklandiae 7g, Fructus Lycii 11g, Semen Cuscutae 9g, Radix Linderae 2g, Lignum Aquilariae Resinatum 7g, Seem Lablab Album 9g, Endothelium Corneum Gigeriae Galli 11g.

Claims (2)

1. treat the Chinese medicine composition of chronic atrophic gastritis for one kind, it is characterized in that, formed by the raw material of Chinese medicine of following weight proportion: Radix Et Rhizoma Nardostachyos 8-12g, Fructus Phyllanthi 5-10g, Rhizoma Atractylodis Macrocephalae 3-8g, Poria 3-8g, Rhizoma Curcumae 1-5g, Radix Aucklandiae 3-8g, Fructus Lycii 8-12g, Semen Cuscutae 5-10g, Radix Linderae 1-5g, Lignum Aquilariae Resinatum 5-10g, Seem Lablab Album 5-10g, Endothelium Corneum Gigeriae Galli 6-12g.
2. the Chinese medicine composition for the treatment of chronic atrophic gastritis according to claim 1, it is characterized in that, formed by the raw material of Chinese medicine of following weight proportion: Radix Et Rhizoma Nardostachyos 10g, Fructus Phyllanthi 8g, Rhizoma Atractylodis Macrocephalae 5g, Poria 5g, Rhizoma Curcumae 3g, Radix Aucklandiae 5g, Fructus Lycii 10g, Semen Cuscutae 8g, Radix Linderae 3g, Lignum Aquilariae Resinatum 7g, Seem Lablab Album 8g, Endothelium Corneum Gigeriae Galli 9g.
CN201410229678.7A 2014-05-27 2014-05-27 Traditional Chinese medicine composition for treating chronic atrophic gastritis Pending CN104013912A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102988870A (en) * 2012-11-30 2013-03-27 北京中融阳光投资管理有限公司 Oral liquid for treating diseases of liver, gall, stomach and intestinal canal

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102988870A (en) * 2012-11-30 2013-03-27 北京中融阳光投资管理有限公司 Oral liquid for treating diseases of liver, gall, stomach and intestinal canal

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
曹连春等: "慢性萎缩性胃炎的中医药治疗", 《实用中西医结合临床》, vol. 7, no. 2, 30 April 2007 (2007-04-30), pages 93 - 94 *
朱春花等: "慢性萎缩性胃炎中医药治疗进展", 《现代中西医结合杂志》 *

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Application publication date: 20140903