CN103212032B

CN103212032B - Traditional Chinese medicine composition for treating gastric diseases

Info

Publication number: CN103212032B
Application number: CN201310148194.5A
Authority: CN
Inventors: 闫忠英
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-04-11
Filing date: 2013-04-11
Publication date: 2015-05-20
Anticipated expiration: 2033-04-11
Also published as: CN103212032A

Abstract

The invention relates to a traditional Chinese medicine composition for treating gastric diseases. The traditional Chinese medicine composition is made from the following raw materials in parts by weight: 7-12 parts of rhizoma bletillae, 7-12 parts of cuttle bone, 4-7 parts of fritillary, 6-10 parts of roasted rhizoma corydalis, 6-10 parts of roasted malt, 5-8 parts of liquorice, 5-7 parts of roasted coptis root, 6-9 parts of betel nut slice, 5-7 parts of elecampane, 8-12 parts of dandelion, 7-10 parts of vinegar curcuma zedoary, 8-12 parts of fried bighead atractylodes rhizome, 5-7 parts of fructus amomi rotundus, 4-6 parts of pericarpium citri reticulatae, 7-10 parts of lithospermum and 7-11 parts of astragalus root.

Description

A kind of Chinese medicine composition for the treatment of gastropathy

Technical field

Invention relates to the field of Chinese medicines, especially, relates to the field of Chinese medicines for the treatment of gastropathy.

Background technology

Gastropathy, is actually the general designation of many diseases.They have similar symptom, as upper abdomen gastral cavilty portion discomfort, pain, after meal glutted, belch, return acid, even Nausea and vomiting etc.Gastropathy common clinically has the innocent and malignant tumour of acute gastritis, chronic gastritis, gastric ulcer, duodenal ulcer, gastroduodenal complex ulcer, polyp of stomach, gastric calculus, stomach, also has prolapse of gastric mucosa, acute gastric dilatation, pyloric obstruction etc.

The symptom of gastritis can very light also can be very heavy, modal have epigastric discomfort or pain, nausea,vomiting,diarrhea, inappetence.The symptom of gastritis and duodenal ulcer is then epigastrium burning pain, particularly between two meals, early occurs before the meal or after drinking orange juice, coffee.Severe patient can have tarry stool, melena or hemafecia.

The medicine of current treatment gastropathy (curing gastritis and ulcers) has Chinese medicine preparation and Western medicine, although can cure, easily recurs.Scientific research proves, patients with gastric disease more than 95% causes a disease because helicobacter pylori (HP) infects, and mostly thoroughly can not kill helicobacter pylori (HP), therefore gastropathy easily recurs in current Chinese medicine and Western medicine.

Summary of the invention

An object of the present invention is to provide a kind of Chinese medicine composition for the treatment of gastropathy, it is made up of the crude drug of following weight portion: Pseudobulbus Bletillae (Rhizoma Bletillae) 7-12 part, Os Sepiae 7-12 part, Bulbus Fritillariae Uninbracteatae 4-7 part, processs Rhizoma Corydalis 6-10 part, Fructus Hordei Germinatus (parched) 6-10 part, Radix Glycyrrhizae 5-8 part, Rhizoma Coptidis (processed) 5-7 part, Semen Arecae sheet 6-9 part, Radix Aucklandiae 5-7 part, Herba Taraxaci 8-12 part, stir-baked RHIIZOMA CURCUMAE with vinegar 7-10 part, Rhizoma Atractylodis Macrocephalae (parched) 8-12 part, roud cardamon seed 5-7 part, Pericarpium Citri Reticulatae 4-6 part, Radix Arnebiae (Radix Lithospermi) 7-10 part, Radix Astragali 7-11 part.

Preferably, the weight proportion of described raw material is: Pseudobulbus Bletillae (Rhizoma Bletillae) 9 parts, Os Sepiae 9 parts, Bulbus Fritillariae Uninbracteatae 5 parts, processs Rhizoma Corydalis 8 parts, Fructus Hordei Germinatus (parched) 8 parts, 6 parts, Radix Glycyrrhizae, Rhizoma Coptidis (processed) 6 parts, Semen Arecae sheet 7 parts, the Radix Aucklandiae 6 parts, Herba Taraxaci 10 parts, stir-baked RHIIZOMA CURCUMAE with vinegar 8 parts, Rhizoma Atractylodis Macrocephalae (parched) 10 parts, roud cardamon seed 6 parts, Pericarpium Citri Reticulatae 5 parts, Radix Arnebiae (Radix Lithospermi) 8 parts, Radix Astragali 9 parts.

Preferably, the manufacture-yellow in described raw material is linked as Fructus Evodiae Rhizoma Coptidis (processed).

Another object of the present invention there is provided the preparation method of described Chinese medicine composition, is specially: crude drug is mixed and made into powder or pill after pulverizing sterilizing.

The instructions of taking of Chinese medicine composition of the present invention is: half an hour ante cibum takes, each 5-7g, three times on the one.The general course for the treatment of is 1 month, and symptom especially severe person can proper extension medicine time.

The function of Chinese medicine composition of the present invention: invigorating the spleen and benefiting QI, clearing away heat-damp and promoting diuresis, promoting blood circulation and stopping pain.

Curing mainly of Chinese medicine composition of the present invention: Stomach duodenum bulb inflammation, the stomachache caused by gastric ulcer, flatulence, acid regurgitation, belch, the symptoms such as inappetence.

The medicine principle of Chinese medicine composition of the present invention:

Monarch drug: Pseudobulbus Bletillae (Rhizoma Bletillae), Os Sepiae, Herba Taraxaci, Pseudobulbus Bletillae (Rhizoma Bletillae) granulation promoting, convergence, hemostasis; Os Sepiae antacid, hemostasis; Herba Taraxaci clearing heat, detoxicating, dispelling dampness, has inhibitory action to stomach Helicobacter pylori (HP).

Ministerial drug: Rhizoma Atractylodis Macrocephalae (parched), Radix Astragali, roud cardamon seed, process Rhizoma Corydalis, Rhizoma Coptidis (processed), Semen Arecae sheet, stir-baked RHIIZOMA CURCUMAE with vinegar, Radix Arnebiae (Radix Lithospermi).Rhizoma Atractylodis Macrocephalae (parched) the spleen strengthening and damp drying; Radix Astragali benefiting qi for promoting granulation; Roud cardamon seed the spleen strengthening and damp drying; Process Rhizoma Corydalis promoting blood circulation and stopping pain; Rhizoma Coptidis (processed) heat clearing and damp drying, has obvious inhibitory action to stomach Helicobacter pylori (HP); Semen Arecae sheet circulation of qi promoting removing food stagnancy, has obvious inhibitory action to stomach Helicobacter pylori (HP); Stir-baked RHIIZOMA CURCUMAE with vinegar blood circulation promoting and blood stasis dispelling is regulated the flow of vital energy, and science proves there is the effect obviously strengthening gastric peristalsis.

Adjuvant drug: Bulbus Fritillariae Uninbracteatae, Fructus Hordei Germinatus (parched), the Radix Aucklandiae.Bulbus Fritillariae Uninbracteatae heat clearing away, eliminating stagnation; Fructus Hordei Germinatus (parched) depressed liver-energy dispersing and QI regulating; Muxiangliqi; Radix Arnebiae (Radix Lithospermi) clearing away heat and cooling blood, removing toxic substances.

Make medicine: Radix Glycyrrhizae, Pericarpium Citri Reticulatae.Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription; Pericarpium Citri Reticulatae is regulated the flow of vital energy appetizing.

Detailed description of the invention:

Embodiment 1

Raw material prepares (weight portion): Pseudobulbus Bletillae (Rhizoma Bletillae) 7 parts, Os Sepiae 7 parts, Bulbus Fritillariae Uninbracteatae 4 parts, process Rhizoma Corydalis 6 parts, Fructus Hordei Germinatus (parched) 6 parts, 5 parts, Radix Glycyrrhizae, Rhizoma Coptidis (processed) 5 parts, Semen Arecae sheet 6 parts, the Radix Aucklandiae 5 parts, Herba Taraxaci 8 parts, stir-baked RHIIZOMA CURCUMAE with vinegar 7 parts, Rhizoma Atractylodis Macrocephalae (parched) 8 parts, roud cardamon seed 5 parts, Pericarpium Citri Reticulatae 4 parts, Radix Arnebiae (Radix Lithospermi) 7 parts, Radix Astragali 7 parts, makes the pill of unit dosage 2.5g after pulverizing sterilizing mixing.

Embodiment 2

Raw material prepares (weight portion): Pseudobulbus Bletillae (Rhizoma Bletillae) 9 parts, Os Sepiae 9 parts, Bulbus Fritillariae Uninbracteatae 5 parts, process Rhizoma Corydalis 8 parts, Fructus Hordei Germinatus (parched) 8 parts, 6 parts, Radix Glycyrrhizae, Rhizoma Coptidis (processed) 6 parts (Fructus Evodiae system), Semen Arecae sheet 7 parts, the Radix Aucklandiae 6 parts, Herba Taraxaci 10 parts, stir-baked RHIIZOMA CURCUMAE with vinegar 8 parts, Rhizoma Atractylodis Macrocephalae (parched) 10 parts, roud cardamon seed 6 parts, Pericarpium Citri Reticulatae 5 parts, Radix Arnebiae (Radix Lithospermi) 8 parts, Radix Astragali 9 parts, makes the powder of unit dosage 2.5g after pulverizing sterilizing mixing.

Embodiment 3

Raw material prepares (weight portion): Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts, Os Sepiae 12 parts, Bulbus Fritillariae Uninbracteatae 7 parts, process Rhizoma Corydalis 10 parts, Fructus Hordei Germinatus (parched) 10 parts, 8 parts, Radix Glycyrrhizae, Rhizoma Coptidis (processed) 7 parts (Fructus Evodiae system), Semen Arecae sheet 9 parts, the Radix Aucklandiae 7 parts, Herba Taraxaci 12 parts, stir-baked RHIIZOMA CURCUMAE with vinegar 10 parts, Rhizoma Atractylodis Macrocephalae (parched) 12 parts, roud cardamon seed 7 parts, Pericarpium Citri Reticulatae 6 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Radix Astragali 11 parts, makes the powder of unit dosage 2.5g after pulverizing sterilizing mixing.

Embodiment 4 (pharmacodynamics)

Randomly draw patients with gastric disease 200 people, wherein man 100 example, female 100 example.Age 20-30 year 40 example, 30-40 year 40 example, 40-50 year 40 example, 50-60 year 40 example, 60-70 year 40 example.

20-30 year group: completely cure 35 example, remission 5 example, invalid 0 example.

30-40 year group: completely cure 36 example, remission 4 example, invalid 0 example.

40-50 year group: completely cure 34 example, remission 6 example, invalid 0 example.

50-60 year group: completely cure 32 example, remission 8 example, invalid 0 example.

60-70 year group: completely cure 28 example, remission 10 example, invalid 2 example.

Special case:

1, king XX, female, 34 years old, Inner Mongol newspaper office office worker, serious peptic gastric ulcer is suffered from before taking medicine, stomach ulcer face is large, with obvious edematous condition, have serious fatigue weak, inappetence, abdominal distention, stomachache, belch, singultus, heartburn, the symptoms such as acid regurgitation, medication is after 15 days, ulcer surface disappears substantially, local is slightly rubescent, still have obvious inflammatory symptom, with edema slightly, fatigue is weak to be alleviated, appetite starts to recover to increase, abdominal distention, stomachache, belch, singultus, heartburn, the symptoms such as acid regurgitation alleviate, occasionally there is generation, medication is after 1 month, ulcer surface disappears completely, inflammation disappears, without obvious edematous condition.

2, open X, man, Inner Mongol private owner, 42 years old, suffers from chronic gastritis medical history 10 years, give omeprazole medication for many years, companion amoxicillin, gastritis disease repeatedly, has no recovery from illness always, inflammatory congestion under gastroscope, has rotten to the corn mucosa phenomenon, congested, has a large amount of histopathology to show secretions.After medication two weeks, under gastroscope, mucosal inflammation alleviates, rotten to the corn range shorter, congested edema alleviates, histopathology shows that secretions reduces, and medication is after 1 month, and under gastroscope, inflammatory congestion disappears, rotten to the corn mucosa recovery from illness, histopathology shows that Active inflammation disappears, the transference cures such as throughout the year adjoint belch, singultus, acid regurgitation, and appetite and digestive function recover normal.

3, Lee XX, man, Inner Mongol state-owned enterprise employee, 56 years old, suffer from serious gastroduodenal compound inflammation, have gastric abscess, feeling of fullness, noisy acid regurgitation, feel sick, bitter taste, xerostomia, glutinous greasy not well, indigestion and loss of appetite, belch, the multiple symptomology such as white and greasy fur, after taking medicine 15 days, inflammation alleviates, congested edema abatement, and relevant stomach abdomen pain, the related symptoms such as to feel sick obviously alleviate, after taking medicine 30 days, inflammation disappears, and edema disappears, and related symptoms etc. all disappear, and compound inflammatory disorders is fully recovered.

Claims

1. treat a Chinese medicine composition for gastropathy, it is characterized in that being made up of the crude drug of following weight portion: Pseudobulbus Bletillae (Rhizoma Bletillae) 7-12 part, Os Sepiae 7-12 part, Bulbus Fritillariae Uninbracteatae 4-7 part, processs Rhizoma Corydalis 6-10 part, Fructus Hordei Germinatus (parched) 6-10 part, Radix Glycyrrhizae 5-8 part, Rhizoma Coptidis (processed) 5-7 part, Semen Arecae sheet 6-9 part, Radix Aucklandiae 5-7 part, Herba Taraxaci 8-12 part, stir-baked RHIIZOMA CURCUMAE with vinegar 7-10 part, Rhizoma Atractylodis Macrocephalae (parched) 8-12 part, roud cardamon seed 5-7 part, Pericarpium Citri Reticulatae 4-6 part, Radix Arnebiae (Radix Lithospermi) 7-10 part, Radix Astragali 7-11 part.

2. Chinese medicine composition according to claim 1, wherein the weight proportion of crude drug is: Pseudobulbus Bletillae (Rhizoma Bletillae) 9 parts, Os Sepiae 9 parts, Bulbus Fritillariae Uninbracteatae 5 parts, processs Rhizoma Corydalis 8 parts, Fructus Hordei Germinatus (parched) 8 parts, 6 parts, Radix Glycyrrhizae, Rhizoma Coptidis (processed) 6 parts, Semen Arecae sheet 7 parts, the Radix Aucklandiae 6 parts, Herba Taraxaci 10 parts, stir-baked RHIIZOMA CURCUMAE with vinegar 8 parts, Rhizoma Atractylodis Macrocephalae (parched) 10 parts, roud cardamon seed 6 parts, Pericarpium Citri Reticulatae 5 parts, Radix Arnebiae (Radix Lithospermi) 8 parts, Radix Astragali 9 parts.

3., according to the Chinese medicine composition of claim 1 or 2, wherein said Rhizoma Coptidis (processed) is Fructus Evodiae Rhizoma Coptidis (processed).

4., according to the Chinese medicine composition of claim 1 or 2, wherein pharmaceutical dosage form is powder or pill.

5. Chinese medicine composition according to claim 3, wherein pharmaceutical dosage form is powder or pill.