CN104069414A - Stomach-comforting pharmaceutical composition and application thereof - Google Patents

Stomach-comforting pharmaceutical composition and application thereof Download PDF

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CN104069414A
CN104069414A CN201410284398.6A CN201410284398A CN104069414A CN 104069414 A CN104069414 A CN 104069414A CN 201410284398 A CN201410284398 A CN 201410284398A CN 104069414 A CN104069414 A CN 104069414A
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parts
parched
pharmaceutical composition
stomach
rhizoma
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CN104069414B (en
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何镔
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TIANCHANG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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TIANCHANG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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Abstract

The invention discloses a stomach-comforting pharmaceutical composition and application thereof. The stomach-comforting pharmaceutical composition comprises the following materials in parts by weight: 5-7 parts of fried radix bupleuri, 9-11 parts of scutellaria baicalensis, 1-3 parts of oroxylum indicum, 14-16 parts of fried white paeony root, 9-11 parts of fried white atractylodes rhizome, 9-11 parts of fried fructus aurantii, 14-16 parts of poria cocos, 9-11 parts of processed pinellia tuber, 14-16 parts of dandelion, 1-3 parts of fructus amomi, 9-11 parts of Sichuan mangnolia officinalis, 9-11 parts of wrinkled giant hyssop, 9-11 parts of perilla stems, 9-11 parts of Thunberg fritillary bulb and 9-11 parts of bletilla striata. The stomach-comforting pharmaceutical composition disclosed by the invention is rigorous in component, integrally regulated from multiple layers, multiple links and multiple target points, remarkable in clinical curative effect for treating reflux esophagitis, obviously improves symptoms, can reduce pathogenetic condition relapse of a patient and can reduce dependence on a proton pump, and is free of toxic and side effect.

Description

A kind of stomach medical composition and its use that relaxes
Technical field
The present invention relates to gastrotherapy drug regimen technical field, relate in particular to a kind of stomach medical composition and its use that relaxes.
Background technology
Gastroesophageal reflux is digestive system commonly encountered diseases, frequently-occurring disease, and crowd's sickness rate increases, and is to flow into the esophagitis sexually transmitted disease (STD) that esophagus causes and become, the breakage that Endoscopic Features is Esophageal Mucosa, i.e. esophagus erosion and/or esophageal ulcer by Stomach duodenum content is counter.Reflux esophagitis can betide the crowd at any age, and adult's sickness rate raises with age growth.The sickness rate generation ascendant trend in the recent two decades whole world.Middle-aged and elderly people, obesity, smoking, drink and stress is greatly the group of people at high risk of reflux esophagitis.The clinical manifestation of gastroesophageal reflux is: 1, the order of severity of esophagitis and reflux symptom non-correlation, patients with reflux esophagitis performance has the classical symptom of gastroesophageal reflux, but also can be without any reflux symptom, only show as the dyspeptic performance such as Upper abdominal pain, discomfort; 2, classical symptom shows as burn feeling after breastbone, anti-stream and chest pain, the heartburn burn feeling that refers to the backward cervical region radiation of breastbone, and anti-stream refers to that gastric content is counter and flows to pharyngeal or oral cavity, reflux symptom is multiple to be born in after heavy meal; 3, esophagus cicatrization is narrow the disease later stage, and burn feeling and burning pain alleviate gradually, but occur permanent acataposis, when feed food, can cause and stop up sense or pain; 4, serious esophagitis person can occur that Esophageal Mucosa is rotten to the corn and it is hemorrhage to cause, and mostly is chronic hemorrhage on a small quantity, can cause iron deficiency anemia.
At present doctor trained in Western medicine to these symptomatic treatments such as acid inhibitors, gastrointestinal prokinetic agent, proton pump inhibitor that adopt more, and clinical recurrence rate is high, especially treat sensitive patients curative effect poor, and it is current technological difficulties that clinical application proton pump inhibitor relies on.For this situation at present without specially good effect Chinese medicine preparation for treating, especially syndrome of liver-stomach heat, mental disorder are handed over resistance etiology and pathogenesis, it is its main disease card type, particularly in clinical, have that the gastral cavilty resistance of alleviation is swollen, the symptom such as belch acid regurgitation, noisy, the scorching hot pain of esophagus, breast gastral cavity stagnation of phlegm, the valuable feature determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of using the traditional Chinese medical science is according to the concrete state of an illness, differential diagnosis of diseases and dialectical being used in conjunction with each other, to formulate the therapeutic scheme of a proper state of an illness.
CN103495142A relates to a kind of Chinese medicine decoction for the treatment of gastroesophageal reflux sexually transmitted disease (STD), and raw material composition is by weight percentage: Pericarpium Citri Reticulatae 5-11, Fructus Toosendan 8-14, Radix Ophiopogonis 5-11, Rhizoma Zingiberis Recens 5-11, Radix Paeoniae Alba 8-14, fevervine 5-11, Rhizoma Corydalis 5-11, Flos Carthami 6-12, Rhizoma Corydalis 6-12, Fructus Gardeniae 6-12, Rhizoma Atractylodis Macrocephalae 5-9, Herba Patriniae 8-14, Flos Chrysanthemi 8-14, long-pending real 6-12.
CN101829310B provides a kind of Chinese medicine preparation for the treatment of reflux esophagitis, crude drug preparation as following weight percent: Rhizoma Pinelliae 5-11, Radix Codonopsis 8-14, Fructus Evodiae 5-11, Rhizoma Zingiberis 5-11, Poria 8-14, Radix Scutellariae 5-11, Rhizoma Coptidis 5-11, Haematitum 6-12, Endoconcha Sepiae 6-12, Fructus Aurantii 6-12, Radix Glycyrrhizae 5-9, Radix Bupleuri 8-14, Radix Paeoniae Alba 8-14, Caulis Bambusae In Taenia 6-12.
CN103638280A discloses a kind of Chinese medicine that is used for the treatment of reflux esophagitis, raw material forms, Radix Paeoniae Rubra 5-11, Fructus Carpesii 8-14, Fructus Ligustri Lucidi 5-11, Rhizoma Cyperi 5-11, Rhizoma Dioscoreae Septemlobae 8-14, Cacumen Platycladi 5-11, Radix Asparagi 5-11, Semen Raphani 6-12, Herba Bidentis Bipinnatae 6-12, Fructus Gardeniae 6-12, Fructus Citri Sarcodactylis 5-9, Fructus Foeniculi 8-14, Pollen Typhae 8-14, Rhizoma Corydalis 6-12.
But above-mentioned three kinds of Chinese medicines for the treatment of reflux esophagitis have reached certain drug effect in treatment, but pharmacodynamic stability is poor, to relatively difficulty of the overall quality control of medicine, and existing Western medicine side effect is larger, can not treating both the principal and the secondary aspects of a disease at the same time, therefore, be necessary to study a kind of clinical efficacy good, have no side effect, reduce the medicine of conditions of patients recurrence and the treatment reflux esophagitis to proton pump inhibitor dependence effect.
Summary of the invention
The technical problem that basic background technology exists, the present invention proposes a kind of stomach medical composition and its use that relaxes, prescription is rigorous, from multi-level, too many levels, the conditioning of many target spots entirety, treatment reflux esophagitis, clinical efficacy is remarkable, obviously improves symptom, can reduce conditions of patients recurrence and to proton pump inhibitor dependence effect, and have no side effect.
The easypro stomach pharmaceutical composition of one that the present invention proposes, its raw material comprises by weight: Radix Bupleuri Chinensis (parched) 5-7 part, Radix Scutellariae 9-11 part, Semen Oroxyli 1-3 part, Radix Paeoniae Alba (parched) 14-16 part, Rhizoma Atractylodis Macrocephalae (parched) 9-11 part, Fructus Aurantii (parched) 9-11 part, Poria 14-16 part, Rhizoma Pinelliae Preparatum 9-11 part, Herba Taraxaci 14-16 part, Fructus Amomi 1-3 part, river is thick flutters 9-11 part, Herba Pogostemonis 9-11 part, Caulis Perillae 9-11 part, Bulbus Fritillariae Thunbergii 9-11 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 9-11 part.
Radix Bupleuri, conventional diaphoretic medicine, wind-heat-dispersing medicinal.Smoke another name, mountain dish, mushroom grass, faggot.Bitter in the mouth, cold nature.Return liver, gallbladder meridian.There is reconciling superficies and interior, dispersing the stagnated live-QI to relieve the stagnation of QI, effect of elevate a turnable ladder yang-energy.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
Generally Radix Bupleuri adopts vinegar method to concoct: get Radix Bupleuri sheet, mix thoroughly with vinegar, put in pot and fry to vinegar exhaustion micro-dry with slow fire, take out, dry, wherein every 100 jin of Radix Bupleuri, with 12 jin of vinegar.The diversity that can reduce Radix Bupleuri after concocting with vinegar, increases its astriction.
Radix Scutellariae, another name Radix Scutellariae, tsuchikane tea root, be a kind of plant of Labiatae Scutellaria, belongs to half kind kind of semi-wild, herbaceos perennial.Bitter in the mouth, cold in nature, returns lung, gallbladder, spleen, stomach, large intestine, small intestine meridian.There is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical practice of Radix Scutellariae is antibacterial not worse than Rhizoma Coptidis, and does not develop immunity to drugs.
Semen Oroxyli is the dry mature seed of Bignoniaceae plant Semen Oroxyli.The mature fruit of gathering in autumn, two seasons of winter, tans by the sun to cracking of fruit, takes out seed, dries.Bitter in the mouth, sweet, cool in nature.Return lung, liver, stomach warp.There is removing heat from the lung and relieving sorethroat, dispersing the stagnated liver-QI for regulating the stomach, effect of expelling pus and promoting granulation.Cure mainly pharyngalgia sore throat, hoarseness, cough, stomachache due to hyperactive liver-QI attacking the stomach, skin infection is burst and is not held back for a long time, acute eczema.
The Radix Paeoniae Alba, bitter in the mouth, acid, cold nature, has the effects such as blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain, astringing YIN to stop sweating, is applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction anxious, dysentery stomachache, spontaneous sweating, metrorrhagia, is with inferior disease.That the paeoniflorin containing in the Radix Paeoniae Alba has is antibacterial, antipyretic, antiinflammatory, increase coronary flow, improve the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjusting blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.
Radix Paeoniae Alba (parched), for getting Radix Paeoniae Alba sheet, is put in pot and is fried to micro-yellow with slow fire, takes out, and cools, and strengthens effect of Radix Paeoniae Alba spleen invigorating tonify deficiency.
The Rhizoma Atractylodis Macrocephalae, another name small wooden raft Ji, Rhizoma Atractylodis Macrocephalae, the winter Rhizoma Atractylodis Macrocephalae, wash rice art, poplar small wooden raft, Wu Shu, sheet art, Rhizoma Atractylodis etc., belong to Compositae [WTBX herbaceos perennial, is used as medicine with rhizome.Bitter in the mouth, sweet, warm in nature, return spleen, stomach warp.There is spleen reinforcing, stomach reinforcing, dampness, and in, antiabortive effect.Cure mainly deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea uneasiness.
Rhizoma Atractylodis Macrocephalae (parched), for first wheat bran being spread in hot pot, when time cigarette is emerged, is poured Rhizoma Atractylodis Macrocephalae sheet into micro-stir-fry to faint yellow, takes out, and sieves and goes to cool after wheat bran, has increased the dry property of the Rhizoma Atractylodis Macrocephalae, energy invigorating the spleen and benefiting QI, and dampness diuretic, hidroschesis, antiabortive.
Fructus Aurantii, bitter in the mouth, pungent, cool in nature, return lung, spleen, large intestine channel, there is effect of dispelling the stagnated QI, row expectorant, removing food stagnancy, cure mainly the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official's prolapsus.
Fructus Aurantii (parched), for getting clean Fructus Aurantii sheet, is put in pot, fry to yellow with slow fire, or fry with high heat to coke yellow, spray clear water a little, the most Mars that goes out, taking-up cools.Fry and relax its property of medicine.
Poria, another name Fu Tu, Poria, Fu Ling, volt Tu,, loose potato, Masson Pine potato, Song Ling etc.Its medicinal part is the sclerotium of On Polyporaceae Poria.Sweet in the mouth, light, property is flat, GUIXIN, spleen, kidney channel.There is promoting diuresis to eliminate damp pathogen, spleen invigorating, the effect of calming the nerves.
Rhizoma Pinelliae Preparatum, is the tuber of the aroid Rhizoma Pinelliae, is class spherical or be broken into irregular particle shape, surperficial yellowish white, yellow or brown color, and matter is more crisp or firmly crisp.Acrid in the mouth, warm in nature, return spleen, stomach, lung meridian.There is effect of drying dampness to eliminate phlegm.Cure mainly dry laryngopharynx, abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache.
Herba Taraxaci, another name Herba crotalariae albidae, Po Poding, Compositae, is a kind of herbaceos perennial.In Herba Taraxaci plant, contain the multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, inulin.Sweet in the mouth, micro-hardship, cold in nature.Return liver, stomach warp.There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.
Fructus Amomi, acrid in the mouth, warm in nature, return spleen, stomach, kidney channel.Xin Wenhang is loose, removing dampness by means of aromatics, main enter taste, for the removing dampness for regulating stomach key medicine of being amusing, have antiabortive merit concurrently.Main Function is in stomach, kidney and the spleen of human body, can circulation of qi promoting seasoning, and stomach function regulating is amusing.Fructus Amomi often coordinates with Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus, Pericarpium Citri Reticulatae etc., the diseases such as treatment fullness in the epigastrium and chest, abdominal distention and little diet.
CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, another name Cortex Magnoliae Officinalis, Cortex Magnoliae Officinalis etc.Bitter in the mouth, pungent, warm in nature.Return spleen, stomach, large intestine channel.There is circulation of qi promoting removing food stagnancy, dampness except effect full, lowering the adverse QI to relieve asthma, cure mainly that stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, gastral cavity painful abdominal mass are vomited and diarrhoea, expectorant is stopped up QI rising in reverse order, fullness in the chest is breathed with cough.Rhizoma Zingiberis makes for it, dislikes Rhizoma Alismatis, Mirabilitum crystallina, Sal Nitri.Avoid bean, the person of food takes offence.Gestation can not take.
Herba Pogostemonis, for the dry aerial parts of Herba Pogostemonis can be used as medicine.When branch and leaf are luxuriant, tap, Exposure to Sunlight is vexed night, repeatedly to dry.Acrid in the mouth, slightly warm in nature.Return spleen, stomach, lung meridian.There is eliminating turbid pathogen with aromatics, and middle preventing or arresting vomiting, deliver effect of expelling summer-heat.For turbid damp obstructing in middle-JIAO, the vomiting of gastral cavity painful abdominal mass, heat-damp in summer exterior syndrome, hygropyrexia is from the beginning of, heating asthenia, uncomfortable in chestly do not relax, and cold-damp is closed summer-heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.
Caulis Perillae is the dry stem of labiate Folium Perillae.Tap after fruit maturation autumn, removes impurity, dries, or take advantage of fresh slices, dries.Acrid in the mouth, warm in nature.Return lung, spleen channel.There is regulating the flow of QI to ease the stomach, pain relieving, antiabortive effect.Vexed for chest and diaphragm painful abdominal mass, gastralgia, belch vomiting, frequent fetal movement.
Bulbus Fritillariae Thunbergii is the bulb of liliaceous plant Bulbus Fritillariae Thunbergii.Excavate early summer, cleans, and large person plucks core bud, claims " Bulbus Fritillariae Thunbergii ", and hit crust, the conch meal of mixing to forge, sucks knocking-on juice, dry.Bitter in the mouth, cold in nature.There is removing heat-phlegm, effect of dissipating depression of QI eliminating stagnation.For wind heat, scorching, phlegm-fire cough, lung abscess, acute mastitis, scrofula, sore, ambition is gloomy.Can play the effect of antacid eliminating stagnation for gastropathy.Join Folium Mori, Flos Chrysanthemi, Fructus Arctii, Semen Armeniacae Amarum and can be used for wind heat, scorching, phlegm-fire cough.Join Radix Scrophulariae, Concha Ostreae can be used for scrofula, sucutaneous nodule.Join Flos Lonicerae, Flos Chrysanthemi, Fructus Forsythiae, Herba Taraxaci and can be used for carbuncle furuncle and phyma poison.Joining Radix Trichosanthis, Herba Taraxaci, Radix Angelicae Sinensis etc. can be used for acute mastitis and swells and ache.
The Pseudobulbus Bletillae (Rhizoma Bletillae), belongs to perennial herb bulbous plant, and the name after its bulb dries is called the Pseudobulbus Bletillae (Rhizoma Bletillae).Bitter in the mouth, sweet, puckery, cold nature.Return lung, liver, stomach warp.There is astringing to arrest bleeding, effect of detumescence and promoting granulation.The all cards of interior external haemorrhage and carbuncle, scald, rhagadia manus et pedis, anal fissure etc.
Above raw material, after optimum organization of the present invention, is made the Chinese medicine preparation for the treatment of the spleen-stomach disease, not only can bring into play separately original effect, more can further strengthen its curative effect, treatment gastroesophageal reflux is better than to the effect of existing medicine.
Preferably, its raw material comprises by weight: Radix Bupleuri Chinensis (parched) 5.5-6.5 part, Radix Scutellariae 9.3-10.2 part, Semen Oroxyli 1.3-2.6 part, Radix Paeoniae Alba (parched) 14.5-15.7 part, Rhizoma Atractylodis Macrocephalae (parched) 9.6-10.4 part, Fructus Aurantii (parched) 9.8-10.2 part, Poria 14.5-15.7 part, Rhizoma Pinelliae Preparatum 9.3-10.4 part, Herba Taraxaci 14.2-15.6 part, Fructus Amomi 1.3-2.5 part, river is thick flutters 9.1-10.9 part, Herba Pogostemonis 9.4-10.6 part, Caulis Perillae 9.2-10.8 part, Bulbus Fritillariae Thunbergii 9.3-10.2 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 9.8-10.1 part.
Preferably, its raw material comprises by weight: 6 parts of Radix Bupleuri Chinensis (parched), 8 parts of Radix Scutellariaes, 2 parts of Semen Oroxylis, 15 parts of Radix Paeoniae Alba (parched)s, 10 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 10 parts of Fructus Aurantii (parched), 15 parts, Poria, 10 parts of Rhizoma Pinelliae Preparatum, 15 parts of Herba Taraxacis, 2 parts of Fructus Amomis, river is thick flutters 10 parts, 10 parts of Herba Pogostemoniss, 10 parts of Caulis Perillaes, 10 parts of Bulbus Fritillariae Thunbergii, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s.
" comprising " of the present invention, mean it except described component, can also comprise other components, these other components give described pharmaceutical composition different characteristics.In addition, " comprising " of the present invention, can also replace with enclosed " being " or " by ... composition ".
Preferably, described easypro stomach pharmaceutical composition is granule.
Chinese medicine preparation refers to that any medicine, for all making the form that is suitable for medical treatment or prophylactic applications before clinical, is called dosage form, such as tablet, injection, aerosol, pill, powder, unguentum etc.Dosage form is collective noun, generally refers to the classification of preparation, any one the concrete kind in dosage form, and such as ZHICHUANLING ZHUSHEYE, the pill of costus and amomum with six noble ingredients in pill etc. in YUANHU ZHITONG PIAN, the injection in tablet is called preparation.And granule is medicine to be coordinated with suitable adjuvant and the granular formulations made, generally can be divided into soluble granule, suspension granule and effervescency granule, if particle diameter, in 105-500 micrometer range, is called again granula subtilis.Its main feature is directly to swallow, also can pour in water, drink into, apply and carry more convenient, stripping and infiltration rate are very fast.
The present invention also proposes the purposes of a kind of above-mentioned easypro stomach pharmaceutical composition in preparation treatment gastroesophageal reflux medicine.
The present invention uses through the clinical practice over more than 10 years, prescription is rigorous, from multi-level, too many levels, the conditioning of many target spots entirety, cure mainly gastroesophageal reflux disease syndrome of liver-stomach heat, mental disorder friendship resistance person, clinical efficacy is remarkable, obviously improves symptom, cure diseases, reduce recurrence, particularly reduce proton pump inhibitor dependence effect, have no side effect, firmly get Building patient trust and welcome.Medicine pill that the present invention makes is through a large amount of clinical uses, and while using 6 months, 80% patient cures substantially, clinical symptoms improvement, and the symptoms such as heartburn, acid regurgitation, regurgitation, chest pain are alleviated to some extent.
Detailed description of the invention
Below, by specific embodiment, technical scheme of the present invention is elaborated.
In embodiment 1-5, the raw material composition as shown in the table by weight of a kind of easypro stomach pharmaceutical composition that the present invention proposes.
The easypro stomach pharmaceutical composition of one that the present invention proposes, function cures mainly: heat clearing away is relaxed, and stomach, regulating QI reduce phlegm, cuticula, for syndrome of liver-stomach heat, the resistance of mental disorder interlocking type gastral cavilty is swollen, chest pain, scorching hot pain, belch acid regurgitation, heartburn noisy, nausea and vomiting, the diseases such as breast gastral cavity stagnation of phlegm, dysphagia.
For the therapeutical effect of test the present invention to gastroesophageal reflux, select 100 routine patients to carry out clinical observation, be divided at random matched group and treatment group, every group of 50 people.Matched group is treated according to a conventional method, and treatment group adopts the made Chinese medicine granules of embodiment 5 to treat, 10g once a bag, three times on the one.
The clinical verification data of this 100 routine sufferer: gastral cavilty resistance is swollen, chest pain, scorching hot pain, belch acid regurgitation, heartburn noisy, nausea and vomiting, breast gastral cavity stagnation of phlegm, dysphagia, or disease predisposition thereby recurrence, red tongue, light red tongue, Tai Bai or Huang, stringy pulse or cunning.
Can be reached a conclusion by upper table: short term efficacy and the late result for the treatment of group treatment gastroesophageal reflux are all better than matched group, and effective prevention of recurrence.
The clinical apparent side effect that has no for the treatment of group; Matched group adopts proton pump inhibitor to have certain irritation to stomach, and after drug withdrawal, gastroesophageal reflux can recur again, makes sufferer produce dependency to proton pump inhibitor.
Based on above-mentioned easypro stomach pharmaceutical composition, the invention allows for the purposes of a kind of above-mentioned easypro stomach pharmaceutical composition in preparation treatment gastroesophageal reflux medicine.
The above; it is only preferably detailed description of the invention of the present invention; but protection scope of the present invention is not limited to this; any be familiar with those skilled in the art the present invention disclose technical scope in; be equal to replacement or changed according to technical scheme of the present invention and inventive concept thereof, within all should being encompassed in protection scope of the present invention.

Claims (5)

1. an easypro stomach pharmaceutical composition, is characterized in that, its raw material comprises by weight: Radix Bupleuri Chinensis (parched) 5-7 part, Radix Scutellariae 9-11 part, Semen Oroxyli 1-3 part, Radix Paeoniae Alba (parched) 14-16 part, Rhizoma Atractylodis Macrocephalae (parched) 9-11 part, Fructus Aurantii (parched) 9-11 part, Poria 14-16 part, Rhizoma Pinelliae Preparatum 9-11 part, Herba Taraxaci 14-16 part, Fructus Amomi 1-3 part, river is thick flutters 9-11 part, Herba Pogostemonis 9-11 part, Caulis Perillae 9-11 part, Bulbus Fritillariae Thunbergii 9-11 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 9-11 part.
2. easypro stomach pharmaceutical composition as claimed in claim 1, it is characterized in that, its raw material comprises by weight: Radix Bupleuri Chinensis (parched) 5.5-6.5 part, Radix Scutellariae 9.3-10.2 part, Semen Oroxyli 1.3-2.6 part, Radix Paeoniae Alba (parched) 14.5-15.7 part, Rhizoma Atractylodis Macrocephalae (parched) 9.6-10.4 part, Fructus Aurantii (parched) 9.8-10.2 part, Poria 14.5-15.7 part, Rhizoma Pinelliae Preparatum 9.3-10.4 part, Herba Taraxaci 14.2-15.6 part, Fructus Amomi 1.3-2.5 part, river is thick flutters 9.1-10.9 part, Herba Pogostemonis 9.4-10.6 part, Caulis Perillae 9.2-10.8 part, Bulbus Fritillariae Thunbergii 9.3-10.2 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 9.8-10.1 part.
3. easypro stomach pharmaceutical composition as claimed in claim 1 or 2, is characterized in that, its raw material comprises by weight: 6 parts of Radix Bupleuri Chinensis (parched), 8 parts of Radix Scutellariaes, 2 parts of Semen Oroxylis, 15 parts of Radix Paeoniae Alba (parched)s, 10 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 10 parts of Fructus Aurantii (parched), 15 parts, Poria, 10 parts of Rhizoma Pinelliae Preparatum, 15 parts of Herba Taraxacis, 2 parts of Fructus Amomis, river is thick flutters 10 parts, 10 parts of Herba Pogostemoniss, 10 parts of Caulis Perillaes, 10 parts of Bulbus Fritillariae Thunbergii, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s.
4. the easypro stomach pharmaceutical composition as described in claim 1-3 any one, is characterized in that, described easypro stomach pharmaceutical composition is granule.
5. the easypro stomach pharmaceutical composition as described in claim 1-4 any one is treated the purposes in gastroesophageal reflux medicine in preparation.
CN201410284398.6A 2014-06-23 2014-06-23 A kind of medical composition and its use for being used to treat gastroesophageal reflux Expired - Fee Related CN104069414B (en)

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Publication number Priority date Publication date Assignee Title
CN104491599A (en) * 2014-12-11 2015-04-08 吴燕 Traditional Chinese medicine composition for treating exudative skin disease
CN105194582A (en) * 2015-11-09 2015-12-30 陈慧珊 Traditional Chinese medicinal oral solution for treating gastritis and preparation method of traditional Chinese medicinal oral solution
CN105582282A (en) * 2016-03-14 2016-05-18 济南正骐生物科技有限公司 Traditional Chinese medicine for treating esophagitis
CN105617215A (en) * 2016-03-02 2016-06-01 金丽丽 Medicine for treating reflux esophagitis
CN105639111A (en) * 2016-01-12 2016-06-08 中国农业科学院特产研究所 Formula of Chinese medicinal herb additive capable of effectively preventing and treating nest separation stress of minks, foxes and racoon dogs, and preparation method of Chinese medicinal herb additive
CN116211953A (en) * 2023-02-09 2023-06-06 北京中医药大学东方医院 Traditional Chinese medicine composition for treating upper abdominal pain syndrome, preparation method and application

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104491599A (en) * 2014-12-11 2015-04-08 吴燕 Traditional Chinese medicine composition for treating exudative skin disease
CN105194582A (en) * 2015-11-09 2015-12-30 陈慧珊 Traditional Chinese medicinal oral solution for treating gastritis and preparation method of traditional Chinese medicinal oral solution
CN105639111A (en) * 2016-01-12 2016-06-08 中国农业科学院特产研究所 Formula of Chinese medicinal herb additive capable of effectively preventing and treating nest separation stress of minks, foxes and racoon dogs, and preparation method of Chinese medicinal herb additive
CN105617215A (en) * 2016-03-02 2016-06-01 金丽丽 Medicine for treating reflux esophagitis
CN105582282A (en) * 2016-03-14 2016-05-18 济南正骐生物科技有限公司 Traditional Chinese medicine for treating esophagitis
CN116211953A (en) * 2023-02-09 2023-06-06 北京中医药大学东方医院 Traditional Chinese medicine composition for treating upper abdominal pain syndrome, preparation method and application

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