CN104069432A - Stomach-harmonizing pharmaceutical composition and application thereof - Google Patents
Stomach-harmonizing pharmaceutical composition and application thereof Download PDFInfo
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Abstract
The invention discloses a stomach-harmonizing pharmaceutical composition which comprises the following materials in parts by weight: 8-12 parts of rhizoma cyperi, 8-12 parts of wrinkled giant hyssop, 8-12 parts of perilla stems, 4-8 parts of fried radix bupleuri, 8-12 parts of white atractylodes rhizome, 8-12 parts of fried fructus aurantii, 4-8 parts of citron peel, 4-8 parts of radix curcumae, 8-12 parts of corydalis tuber, 8-12 parts of fructus toosendan, 4-8 parts of frankincense, 4-8 parts of aspongopus, 13-17 parts of semen raphani, 13-17 parts of semen cassia, 13-17 parts of hawthorns and 13-17 parts of medicated leaven. The invention further discloses application of the stomach-harmonizing pharmaceutical composition in preparation of a drug for treating liver-qi and stomach-qi stagnation, and dysfunction of spleen in transportation. The stomach-harmonizing pharmaceutical composition disclosed by the invention not only has the effects of regulating the flow of qi to alleviate pain and promoting gastrointestinal motility, but also has the effects of tonifying spleen and descending, resolving resolving food stagnation.
Description
Technical field
The present invention relates to digestive system disease medicine technical field, relate in particular to a kind of stomach function regulating medical composition and its use.
Background technology
Digestive system disease is commonly encountered diseases and frequently-occurring disease clinically, the most common with gastritis, gastric ulcer, esophagitis, duodenal bulbar ulcer, functional dyspepsia etc. in digestive system disease, often because of diseases caused by exogenous pathogenic factor six climate exopathogens, injury due to diet, feelings will internal injury, work and rest are irregular and repeatedly bring out and increase the weight of, clinical manifestation is that flatulence, stomachache, belch, noisy, anorexia etc. are main, there are the multiple syndromes such as deficiency-weakness of spleen-QI, spleen YANG deficiency, stomach-Yin virtual loss, damp and hot middle resistance though dialectical, but with stagnation of liver-QI and stomach-QI, spleen fortune is lost and is good for as the most common.Crowd's sickness rate is high, doctor trained in Western medicine adopts the symptomatic treatment such as acid inhibitor, gastrointestinal prokinetic agent to the digestive system disease of this kind of pattern of syndrome more at present, to this type of the spleen-stomach disease without effective treatment means, though exist the similar medicine that is used for the treatment of the spleen-stomach disease all to have the therapeutical effect to taste on market, the valuable feature determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of the traditional Chinese medical science will be according to the concrete state of an illness, differential diagnosis of diseases and dialectical being used in conjunction with each other, can regulating QI to relieve pain, relieving distension, promote digestive tract power effect, can also spleen invigorating is logical fall, change stagnant helping digestion.
Summary of the invention
The technical problem that basic background technology exists, the present invention proposes a kind of stomach function regulating pharmaceutical composition, not only has regulating QI to relieve pain, relieving distension, promotes digestive tract power effect, also has that spleen invigorating is logical falls, and changes the stagnant effect such as help digestion.
A kind of stomach function regulating pharmaceutical composition that the present invention proposes, its raw material comprises by weight: Rhizoma Cyperi 8-12 part, Herba Pogostemonis 8-12 part, Caulis Perillae 8-12 part, Radix Bupleuri Chinensis (parched) 4-8 part, Rhizoma Atractylodis Macrocephalae 8-12 part, Fructus Aurantii (parched) 8-12 part, Pericarpium Citri 4-8 part, radix curcumae 4-8 part, Rhizoma Corydalis 8-12 part, Fructus Toosendan 8-12 part, Olibanum 4-8 part, Aspongopus 4-8 part, Semen Raphani 13-17 part, Semen Cassiae 13-17 part, Fructus Crataegi 13-17 part, Massa Medicata Fermentata 13-17 part.
Rhizoma Cyperi, acrid in the mouth, micro-hardship, sweet, property is flat.Enter liver, tri-jiao channel.There is the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving, antiabortive effect.Cure mainly distending pain over the hypochondrium, mammary swelling is educated, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation, bleeding not during menses, frequent fetal movement.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.Raw with the pain relieving of can inducing sweat.
Herba Pogostemonis, for the dry aerial parts of Herba Pogostemonis can be used as medicine.When branch and leaf are luxuriant, tap, Exposure to Sunlight is vexed night, repeatedly to dry.Acrid in the mouth, slightly warm in nature.Return spleen, stomach, lung meridian.There is eliminating turbid pathogen with aromatics, and middle preventing or arresting vomiting, deliver effect of expelling summer-heat.For turbid damp obstructing in middle-JIAO, the vomiting of gastral cavity painful abdominal mass, heat-damp in summer exterior syndrome, hygropyrexia is from the beginning of, heating asthenia, uncomfortable in chestly do not relax, and cold-damp is closed summer-heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.
Caulis Perillae is the dry stem of labiate Folium Perillae.Tap after fruit maturation autumn, removes impurity, dries, or take advantage of fresh slices, dries.Acrid in the mouth, warm in nature.Return lung, spleen channel.There is regulating the flow of QI to ease the stomach, pain relieving, antiabortive effect.Vexed for chest and diaphragm painful abdominal mass, gastralgia, belch vomiting, frequent fetal movement.
Radix Bupleuri, conventional diaphoretic medicine, wind-heat-dispersing medicinal.Smoke another name, mountain dish, mushroom grass, faggot.Bitter in the mouth, cold nature.Return liver, gallbladder meridian.There is reconciling superficies and interior, dispersing the stagnated live-QI to relieve the stagnation of QI, effect of elevate a turnable ladder yang-energy.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
Generally Radix Bupleuri adopts vinegar method to concoct: get Radix Bupleuri sheet, mix thoroughly with vinegar, put in pot and fry to vinegar exhaustion micro-dry with slow fire, take out, dry, wherein every 100 jin of Radix Bupleuri, with 12 jin of vinegar.The diversity that can reduce Radix Bupleuri after concocting with vinegar, increases its astriction.
The Rhizoma Atractylodis Macrocephalae, another name small wooden raft Ji, Rhizoma Atractylodis Macrocephalae, the winter Rhizoma Atractylodis Macrocephalae, wash rice art, poplar small wooden raft, Wu Shu, sheet art, Rhizoma Atractylodis etc., belong to Compositae [WTBX herbaceos perennial, is used as medicine with rhizome.Bitter in the mouth, sweet, warm in nature, return spleen, stomach warp.There is spleen reinforcing, stomach reinforcing, dampness, and in, antiabortive effect.Cure mainly deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea uneasiness.
Fructus Aurantii, bitter in the mouth, pungent, cool in nature, return lung, spleen, large intestine channel, there is effect of dispelling the stagnated QI, row expectorant, removing food stagnancy, cure mainly the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official's prolapsus.
Fructus Aurantii (parched), for getting clean Fructus Aurantii sheet, is put in pot, fry to yellow with slow fire, or fry with high heat to coke yellow, spray clear water a little, the most Mars that goes out, taking-up cools.Fry and relax its property of medicine.
Pericarpium Citri, ancient times, " book on Chinese herbal medicine " contained Fructus Citri referred to citron more, sometimes including Fructus Citri Sarcodactylis.But the source of commodity Fructus Citri at present, have citron and two kinds of fragrant circles, and output is taking the latter as large, uses also wider.Acrid in the mouth, hardship, acid, warm in nature, return liver, spleen, lung meridian, there is liver-smoothing, qi-regulating, alleviating distention in middle-JIAO, clears phlegm.For stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavity abdomen feeling of fullness, vomiting eructation, abundant expectoration cough.
Radix curcumae, i.e. Radix Curcumae, Curcuma perennial root herbaceous plant.Acrid in the mouth, hardship, cold in nature, return liver, the heart, lung meridian, there is the use of regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire.Cure mainly all pains of breast abdomen side of body rib, lose the heart demented, calentura coma, spits blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.
Rhizoma Corydalis, Rhizoma Corydalis, has another name called Rhizoma Corydalis, Rhizoma Corydalis.Acrid in the mouth, hardship, warm in nature, nontoxic, enter liver, stomach, heart channel, have invigorate blood circulation, circulation of qi promoting, pain relieving effect.For all pain cards of stagnation of QI-blood; The pungent loose temperature of this product is logical, and " stagnation of QI in energy promoting the circulation of blood, stasis in gas, therefore specially control upper and lower all pains all over the body ", analgesic effect is strong.Be usually used in obstruction of qi in the chest and cardialgia, stomachache, stagnation of QI due to depression of the liver distending pain over the hypochondrium, dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal, colic of cold type stomachache, traumatic injury, rheumatic arthralgia etc.
Fructus Toosendan, bitter in the mouth, cold in nature, slightly poisonous.Return liver, small intestinal, urinary bladder channel.There are soothing liver-QI promoting the circulation of QI to relieve pain, except damp and hot, effect of anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.
Olibanum, real name smokes land, and the smoked Lu Xiang of another name, horse hair perfume (or spice), nipple perfume (or spice), the perfume (or spice) that collapses, it pool is fragrant, Moller is fragrant, many gals Luo Xiang etc.Acrid in the mouth, hardship, warm in nature.Enter the heart, liver, spleen channel.Regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Aspongopus, salty in the mouth, warm in nature.Return liver,spleen,kidney warp.Regulating QI to relieve pain, warming middle-JIAO is supporing yang.For cold syndrome of the stomach distending pain, stomachache due to hyperactive liver-QI attacking the stomach, impotence due to deficiency of the kidney, soreness of waist and knee joint.Containing Aspongopus oil, in oil, containing stearic acid, Palmic acid, oleic acid, its stink derives from aldehydes or ketones, also, containing protein, chitin etc., staphylococcus aureus, Bacillus typhi, Salmonella paratyphi, shigella flexneri is had to stronger antibacterial action; And there is a body metabolism of promotion.
Semen Raphani, Semen Raphani, another name Semen Raphani, trailing plants white chessman, Semen Raphani, be the mature seed of crucifer Radix Raphani.Acrid in the mouth, sweet, property is flat, returns lung, spleen, stomach warp.The de-swelling that helps digestion, lowering the adverse-rising QI to resolve phlegm.Cure mainly stagnation of QI due to dyspepsia, distension and fullness in the abdomen, belch, heavy after dysentery, cough with copious phlegm, dyspnea with rapid and short breath fullness in the chest.Enter spleen, stomach, lung meridian, the de-swelling that can help digestion, effect is remarkable, has the title of " rush wall fall wall ".Clinical habit is used for the treatment of excess syndrome.But these product are not only the de-swellings that helps digestion, and deficiency syndrome, with it, are obtained to effect also good, because of its property peace, its abnormal smells from the patient is not high again, and what without the fraud of victory partially, can not be limited to " rush wall fall wall " says there is the suspicion of dispelling the stagnated QI, is having a surplus of flat gas actually, and gives it up.
Semen Cassiae, Semen Cassiae is the dry mature seed of leguminous plant Semen Cassiae or little Semen Cassiae.The mature fruit of gathering autumn, dries, and lays seed, removes impurity.Bitter in the mouth, cold nature.Return liver, large intestine channel.Clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, nyctalopia, hypertension, hepatitis, cirrhotic ascites, constipation.
Fructus Crataegi, sour in the mouth, sweet, slightly warm in nature, enters spleen, stomach, Liver Channel.Have help digestion long-pending, dissipating blood stasis blood, taenifugal effect.Cure mainly meat long-pending, lump in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis etc.For meat stagnation, stomach alkane distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain, hyperlipidemia.
Massa Medicata Fermentata, bitter in the mouth, warm in nature, enter spleen, stomach, large intestine channel.There is strengthening the spleen to promote digestion, regulating QI to expel dampness, the effect of inducing sweat.Cure mainly the feeling of stuffiness in chest of getting ill from overeating, stomachache is vomited and diarrhoea, dysentery, and headache due to common cold, children's hinders hungry mistake and satisfies.
Above raw material, after optimum organization of the present invention, is made the Chinese medicine preparation for the treatment of the spleen-stomach disease, not only can bring into play separately original effect, more can further strengthen its curative effect, treatment digestive tract disease is better than to the effect of existing medicine.
Preferably, its raw material comprises by weight: Rhizoma Cyperi 9-11 part, Herba Pogostemonis 9.6-10.4 part, Caulis Perillae 8.5-11.2 part, Radix Bupleuri Chinensis (parched) 4.3-7.7 part, Rhizoma Atractylodis Macrocephalae 9-11 part, Fructus Aurantii (parched) 9.6-10.1 part, Pericarpium Citri 4.9-6.8 part, radix curcumae 5-7 part, Rhizoma Corydalis 9.2-10.6 part, Fructus Toosendan 9.4-10.2 part, Olibanum 5.6-6.4 part, Aspongopus 4.8-7.3 part, Semen Raphani 14.4-15.7 part, Semen Cassiae 13.2-16.6 part, Fructus Crataegi 14-16 part, Massa Medicata Fermentata 14.9-15.2 part.
Preferably, its raw material comprises by weight: 10 parts of Rhizoma Cyperis, 10 parts of Herba Pogostemoniss, 10 parts of Caulis Perillaes, 6 parts of Radix Bupleuri Chinensis (parched), 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Fructus Aurantii (parched), 6 parts of Pericarpium Citris, 6 parts of radix curcumaes, 10 parts of Rhizoma Corydalis, 10 parts of Fructus Toosendan, 6 parts of Olibanums, 6 parts of Aspongopuss, 15 parts of Semen Raphanis, 15 parts of Semen Cassiaes, 15 parts of Fructus Crataegis, 15 parts of Massa Medicata Fermentata.
" comprising " of the present invention, mean it except described component, can also comprise other components, these other components give described pharmaceutical composition different characteristics.In addition, " comprising " of the present invention, can also replace with enclosed " being " or " by ... composition ".
Preferably, described easypro stomach pharmaceutical composition is granule.
Chinese medicine preparation refers to that any medicine, for all making the form that is suitable for medical treatment or prophylactic applications before clinical, is called dosage form, such as tablet, injection, aerosol, pill, powder, unguentum etc.Dosage form is collective noun, generally refers to the classification of preparation, any one the concrete kind in dosage form, and such as ZHICHUANLING ZHUSHEYE, the pill of costus and amomum with six noble ingredients in pill etc. in YUANHU ZHITONG PIAN, the injection in tablet is called preparation.And granule is medicine to be coordinated with suitable adjuvant and the granular formulations made, generally can be divided into soluble granule, suspension granule and effervescency granule, if particle diameter, in 105-500 micrometer range, is called again granula subtilis.Its main feature is directly to swallow, also can pour in water, drink into, apply and carry more convenient, stripping and infiltration rate are very fast.
The present invention also proposes a kind of described stomach function regulating pharmaceutical composition and loses the purposes in strong medicine in preparation treatment stagnation of liver-QI and stomach-QI, spleen fortune.
Medication of the present invention is without the large bitter suspicion of damaging sun Great Cold, again without the fraud of capturing pathogenic fire purging, though medicine temperature partially, but temperature is not and dry, and Wu the effect of Hao Robbery impairment of YIN, liver spleen is ruled together, dispersing the stagnated liver-QI for regulating the stomach, QI and blood is adjusted altogether, not only has regulating QI to relieve pain, relieving distension, promote digestive tract power effect, also have that spleen invigorating is logical falls, change the stagnant effect such as help digestion, cure mainly disharmony between the liver and spleen, liver-stomach disharmony type taste patient, clinical efficacy is remarkable, has no side effect, cheap, firmly get Building patient trust and welcome.
Detailed description of the invention
Below, by specific embodiment, technical scheme of the present invention is elaborated, in embodiment 1-5, a kind of raw material for stomach function regulating pharmaceutical composition composition as shown in the table by weight that the present invention proposes.
Function of the present invention cures mainly: dispersing the stagnated liver-QI for regulating the stomach, and spleen invigorating helps fortune, the relieving distension of regulating the flow of vital energy; For disharmony between the liver and spleen, incoordination between the liver and stomach, cure mainly the disease of stomachache, flatulence, noisy, belch, anorexia.
For test the present invention loses strong therapeutical effect to stagnation of liver-QI and stomach-QI, spleen fortune, select 120 routine patients to carry out clinical observation, be divided at random matched group and treatment group, every group of 60 people.Matched group is treated according to a conventional method, and treatment group adopts the made Chinese medicine granules of embodiment 5 to treat, and three times on the one, each 5g.
The clinical verification data of this 120 routine sufferer: epigastric distending pain or companion's two side of body distending pains, gastric upset and eructation, anorexia, feelings will not Shu Ze increases the weight of, light red tongue white and thin fur, stringy pulse.
Drawn by upper table: treatment group can be recovered health faster with respect to matched group.
Medicine pill of the present invention is through being widely used for a long time, and clinical cure rate reaches 85%, and effective percentage reaches 90%.
Based on above-mentioned stomach function regulating pharmaceutical composition, the invention allows for a kind of above-mentioned stomach function regulating pharmaceutical composition and lose the purposes in strong medicine in preparation treatment stagnation of liver-QI and stomach-QI, spleen fortune.
The above; it is only preferably detailed description of the invention of the present invention; but protection scope of the present invention is not limited to this; any be familiar with those skilled in the art the present invention disclose technical scope in; be equal to replacement or changed according to technical scheme of the present invention and inventive concept thereof, within all should being encompassed in protection scope of the present invention.
Claims (5)
1. a stomach function regulating pharmaceutical composition, is characterized in that, its raw material comprises by weight: Rhizoma Cyperi 8-12 part, Herba Pogostemonis 8-12 part, Caulis Perillae 8-12 part, Radix Bupleuri Chinensis (parched) 4-8 part, Rhizoma Atractylodis Macrocephalae 8-12 part, Fructus Aurantii (parched) 8-12 part, Pericarpium Citri 4-8 part, radix curcumae 4-8 part, Rhizoma Corydalis 8-12 part, Fructus Toosendan 8-12 part, Olibanum 4-8 part, Aspongopus 4-8 part, Semen Raphani 13-17 part, Semen Cassiae 13-17 part, Fructus Crataegi 13-17 part, Massa Medicata Fermentata 13-17 part.
2. stomach function regulating pharmaceutical composition as claimed in claim 1, it is characterized in that, its raw material comprises by weight: Rhizoma Cyperi 9-11 part, Herba Pogostemonis 9.6-10.4 part, Caulis Perillae 8.5-11.2 part, Radix Bupleuri Chinensis (parched) 4.3-7.7 part, Rhizoma Atractylodis Macrocephalae 9-11 part, Fructus Aurantii (parched) 9.6-10.1 part, Pericarpium Citri 4.9-6.8 part, radix curcumae 5-7 part, Rhizoma Corydalis 9.2-10.6 part, Fructus Toosendan 9.4-10.2 part, Olibanum 5.6-6.4 part, Aspongopus 4.8-7.3 part, Semen Raphani 14.4-15.7 part, Semen Cassiae 13.2-16.6 part, Fructus Crataegi 14-16 part, Massa Medicata Fermentata 14.9-15.2 part.
3. stomach function regulating pharmaceutical composition as claimed in claim 2, is characterized in that, its raw material comprises by weight: 10 parts of Rhizoma Cyperis, 10 parts of Herba Pogostemoniss, 10 parts of Caulis Perillaes, 6 parts of Radix Bupleuri Chinensis (parched), 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Fructus Aurantii (parched), 6 parts of Pericarpium Citris, 6 parts of radix curcumaes, 10 parts of Rhizoma Corydalis, 10 parts of Fructus Toosendan, 6 parts of Olibanums, 6 parts of Aspongopuss, 15 parts of Semen Raphanis, 15 parts of Semen Cassiaes, 15 parts of Fructus Crataegis, 15 parts of Massa Medicata Fermentata.
4. stomach function regulating pharmaceutical composition as described in claim 1-3 any one, is characterized in that, described stomach function regulating pharmaceutical composition is granule.
One kind as described in claim 1-4 any one stomach function regulating pharmaceutical composition lose the purposes in strong medicine in preparation treatment stagnation of liver-QI and stomach-QI, spleen fortune.
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| CN105055740A (en) * | 2015-07-16 | 2015-11-18 | 王乾林 | Traditional Chinese medicine pharmaceutical for treating heartburn |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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