CN105194582A - Traditional Chinese medicinal oral solution for treating gastritis and preparation method of traditional Chinese medicinal oral solution - Google Patents

Traditional Chinese medicinal oral solution for treating gastritis and preparation method of traditional Chinese medicinal oral solution Download PDF

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CN105194582A
CN105194582A CN201510755147.6A CN201510755147A CN105194582A CN 105194582 A CN105194582 A CN 105194582A CN 201510755147 A CN201510755147 A CN 201510755147A CN 105194582 A CN105194582 A CN 105194582A
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parts
rhizoma
radix
filtrate
subsequent use
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陈慧珊
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Abstract

The invention discloses a traditional Chinese medicinal oral solution for treating gastritis and a preparation method of the traditional Chinese medicinal oral solution. The oral solution is prepared from the following raw materials in parts by weight: 9-15 parts of radix bupleuri, 6-12 parts of fructus aurantii, 12-18 parts of herba eupatorii, 9-15 parts of rose flowers, 9-15 parts of notopterygium root, 17-23 parts of dandelion, 12-18 parts of magnolia officinalis, 7-13 parts of amomum cardamomum, 7-13 parts of rhizoma acori graminei, 6-12 parts of sandalwood, 9-18 parts of rhizoma atractylodis macrocephalae, 6-12 parts of perilla stem, 12-18 parts of radix curcumae and 7-13 parts of poria cocos. The traditional Chinese medicinal oral solution has the effects of regulating qi, relieving middle-jiao, clearing heat, removing toxicity, promoting appetite, relieving pain, removing stagnation and diminishing swelling, and is a safe and reliable traditional Chinese medicine composition with no toxic or side effect, high efficient ingredient usage rate and quick response.

Description

A kind of Chinese medicine oral liquid and preparation method for the treatment of gastritis
Technical field
The present invention relates to a kind of Chinese medicine oral liquid for the treatment of gastritis, belong to the field of Chinese medicines.
Background technology
Gastritis is the gastric mucosa acute and chronic inflammation that multiple different pathogeny causes, often with epithelial damage, mucosal inflammation reaction and epithelium regeneration, it is one of modal digestive system disease, the clinical manifestation of different gastritis can be different, common clinical manifestation: (one) upper abdominal pain: most of gastritis sufferer has upper abdominal pain, epigastrium pain majority is irregular, and have nothing to do with diet, pain is generally diffusivity epigastrium causalgia, dull pain, distending pain etc.; (2) abdominal distention: some patients can feel abdominal distention, usually because gastric retention food, emptying delay, caused by dyspepsia; (3) belch: have belch, shows that gastric gas increases, and discharges, make Abdeminal pain respite through esophagus; (4) Repeated Hemorrhage: hemorrhage is that a kind of gastric mucosa acute inflammation concurrent on gastritis basis changes; (5) other: inappetence, acid regurgitation, Nausea and vomiting, weak, constipation or diarrhoea etc.; (6) sign: have upper abdomen tenderness during inspection, small number of patients can be become thin and anemia; Primary disease belongs to the category such as Chinese medicine " gastric abscess ", " epigastric pain ", " acid regurgitation ", " stomach painful abdominal mass ", and glutted after clinical visible gastral cavity abdomen discomfort, dull pain, burning pain, food, these symptoms are generally without obvious rhythmicity, and feed can increase the weight of or alleviate; In addition can have loss of appetite, belch, feel sick, pantothenic acid etc., the diseases such as the later stage can occur malaise, becomes thin, pernicious anemia, morbidity many by eating and drinking without temperance, overstrain too, feelings will is smooth so that taste are impaired, functional activity of QI being not smooth, caused by middle Jiao's lifting imbalance, the western medical treatment Main Means taked this disease at present uses antibiotic etc, but western medicine is temporary transient symptom management mostly, and life-time service easily produces dependency and toxic and side effects.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine oral liquid for the treatment of gastritis, it has effect of regulating the flow of QI to ease the stomach, heat-clearing and toxic substances removing, appetizing pain relieving, the stagnant relieving distension of row.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine oral liquid for gastritis, be made up of following raw material: Radix Bupleuri 9-15 part, Fructus Aurantii 6-12 part, Herba Eupatorii 12-18 part, Flos Rosae Rugosae 9-15 part, Rhizoma Et Radix Notopterygii 9-15 part, Herba Taraxaci 17-23 part, Cortex Magnoliae Officinalis 12-18 part, Fructus Amomi Rotundus 7-13 part, Rhizoma Acori Graminei 7-13 part, Lignum Santali Albi 6-12 part, Rhizoma Atractylodis Macrocephalae 9-18 part, Caulis Perillae 6-12 part, Radix Curcumae 12-18 part, Poria 7-13 part.
Preferably, each parts by weight of raw materials is: Radix Bupleuri 12 parts, Fructus Aurantii 9 parts, Herba Eupatorii 15 parts, Flos Rosae Rugosae 12 parts, Rhizoma Et Radix Notopterygii 12 parts, Herba Taraxaci 20 parts, Cortex Magnoliae Officinalis 15 parts, Fructus Amomi Rotundus 10 parts, Rhizoma Acori Graminei 10 parts, 9 parts, Lignum Santali Albi, the Rhizoma Atractylodis Macrocephalae 15 parts, Caulis Perillae 9 parts, Radix Curcumae 15 parts, 10 parts, Poria.
Pharmacological action:
Radix Bupleuri: nature and flavor with return through: bitter, be slightly cold; Return liver, gallbladder meridian, function with cure mainly: reconciling superficies and interior, soothing the liver, yang invigorating; For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
Fructus Aurantii: nature and flavor with return through: bitter, pungent, sour, temperature; Return spleen, stomach warp, function with cure mainly: regulating the flow of QI to ease the stomach, row stagnant relieving distension; For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official's prolapsus.
Herba Eupatorii: nature and flavor with return through: pungent, flat; Return spleen, stomach, lung meridian, function with cure mainly: removing dampness by means of aromatics, appetizing of being amusing, delivers expelling summer-heat; For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass vomiting and nausea, sweet greasy in mouth, halitosis, sialism, heat-damp in summer table disease, feeling of fullness in the head is uncomfortable in chest.
Flos Rosae Rugosae: nature and flavor with return through sweet, micro-hardship, temperature; Return liver, spleen channel, function with cure mainly: promoting QI circulation for relieving depression, and blood, pain relieving; For stomachache due to hyperactive liver-QI attacking the stomach, lack of appetite vomiting and nausea, menoxenia, falls and flutters the pain of injury.
Rhizoma Et Radix Notopterygii: nature and flavor with return through: pungent, bitter, temperature; Return bladder, kidney channel, function with cure mainly: cold expelling, dispel the wind, dehumidifying, pain relieving; For anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.
Herba Taraxaci: nature and flavor with return through: bitter, sweet, cold; Return liver, stomach warp, function with cure mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome; For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Cortex Magnoliae Officinalis: nature and flavor with return through: bitter, pungent, temperature; Return spleen, stomach, lung, large intestine channel, function with cure mainly: dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full; For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.
Fructus Amomi Rotundus: nature and flavor with return through: pungent, temperature; Return lung, spleen, stomach warp, function with cure mainly: removing dampness disappears painful abdominal mass, circulation of qi promoting warming middle-JIAO, appetite-stimulating indigestion-relieving; For turbid damp obstructing in middle-JIAO, anorexia, hygropyrexia from the beginning of, uncomfortable in chest not hungry, cold-damp vomiting, chest and abdomen swelling and pain, food stagnation does not disappear.
Rhizoma Acori Graminei: nature and flavor with return through: pungent, bitter, temperature; GUIXIN, stomach warp, function with cure mainly: removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae; Not hungry for gastral cavity painful abdominal mass, a mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.
Lignum Santali Albi: nature and flavor with return through: pungent, temperature; Return spleen, stomach, the heart, lung meridian, function with cure mainly: circulation of qi promoting warming middle-JIAO, appetizing pain relieving; For QI stagnated by cold, chest pain, stomachache, stomachache lack of appetite; Coronary heart disease, angina pectoris.
The Rhizoma Atractylodis Macrocephalae: nature and flavor with return through: bitter, sweet, temperature; Return spleen, stomach warp, function with cure mainly: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive; For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement; Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive; For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
Caulis Perillae: nature and flavor with return through: pungent, temperature; Return lung, spleen channel, function with cure mainly: regulating the flow of QI to ease the stomach, pain relieving, antiabortive; Vexed for chest and diaphragm painful abdominal mass, gastralgia, belch is vomitted, frequent fetal movement.
Radix Curcumae: nature and flavor with return through: pungent, bitter, cold; Return liver, the heart, lung meridian, function with cure mainly: regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice; For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.
Poria: nature and flavor with return through: sweet, light, flat; GUIXIN, lung, spleen, kidney channel, function with cure mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming; For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Another technical problem to be solved by this invention is to provide a kind of preparation method preparing above-mentioned Chinese medicine oral liquid.
Another technical problem to be solved by this invention is achieved through the following technical solutions:
Treat a preparation method for the Chinese medicine oral liquid of gastritis, be prepared from by following methods:
(1) raw material Radix Bupleuri, Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, 10-20 order is ground into after oven dry, for subsequent use;
(2) get raw material Flos Rosae Rugosae, Herba Taraxaci cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, is ground into 10-20 order after oven dry, for subsequent use;
(3) Radix Bupleuri after pulverizing in step (1), Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria are put into machine for decocting Chinese traditional herb medicines, soak 10-20min, amount of water is 8-12 times of above-mentioned raw materials gross weight, decoct under 60-100 DEG C of condition, time is 1-3h, then filter, obtain filtrate and medicinal residues; Flos Rosae Rugosae after pulverizing in step (2), Herba Taraxaci are put into machine for decocting Chinese traditional herb medicines and soaked 10-20min, and amount of water is 8-12 times of above-mentioned raw materials gross weight, decocts under 60-100 DEG C of condition, time is 1-3h, then filters, and obtains filtrate and medicinal residues, after being merged by twice medicinal residues, amount of water is 5-10 times of medicinal residues gross weight, and decoct under 60-100 DEG C of condition, the time is 10-30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, and revolution 10000-28000r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of gastritis.
Preferably, a kind of preparation method of Chinese medicine oral liquid for the treatment of gastritis, is prepared from by following methods:
(1) raw material Radix Bupleuri, Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2m/s, and drying time is 1h, 20 orders are ground into after oven dry, for subsequent use;
(2) get raw material Flos Rosae Rugosae, Herba Taraxaci cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2m/s, and drying time is 1h, is ground into 20 orders after oven dry, for subsequent use;
(3) Radix Bupleuri after pulverizing in step (1), Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria are put into machine for decocting Chinese traditional herb medicines, soak 20min, amount of water is 12 times of above-mentioned raw materials gross weight, decoct under 83 DEG C of conditions, time is 1h, then filter, obtain filtrate and medicinal residues; Flos Rosae Rugosae after pulverizing in step (2), Herba Taraxaci are put into machine for decocting Chinese traditional herb medicines and soaked 20min, and amount of water is 12 times of above-mentioned raw materials gross weight, decocts under 83 DEG C of conditions, time is 1h, then filters, and obtains filtrate and medicinal residues, twice medicinal residues is merged 10 times that amount of water is above-mentioned raw materials gross weight, and decoct under 75 DEG C of conditions, the time is 30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 105mm, and revolution 16500r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.2 μm, and pressure is 0.05MPa, and crossflow velocity is 4m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, when being evaporated to 60 DEG C in concentration tank, the clear paste of relative density 1.08, obtains clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 83 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100 DEG C, time is 15min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of gastritis.
Beneficial effect: the present invention has effect of regulating the flow of QI to ease the stomach, heat-clearing and toxic substances removing, appetizing pain relieving, the stagnant relieving distension of row, be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
The present invention adopts pure Chinese medicine to be raw material, according to pathogenic factor and the Clinical symptoms of gastritis, under instruction of Chinese Medicine theory, carry out prescription be prepared from the basis not being raw-material activity, show through clinical efficacy, this medicine has definite curative effect to gastritis, is the ideal treatment medication of a kind of gastritis sufferer.
Model case
Case 1: Mrs Hong, 40 years old, medical history: patient main suit's gastral cavity abdominal distention vexed several days, after food more very, tastelessness is dull, disease belongs to: liver violates stomach, and wet tired spleen, takes Drug therapy of the present invention one week, the vexed obvious minimizing of patient's conscious gastral cavity abdominal distention after treatment, appetite is normal, and after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 2: Mrs Tao, 28 years old, medical history: patient main suit's gastral cavilty portion pain, often with inappetence, vexed or the distension of painful abdominal mass, nausea and vomiting, acid regurgitation and epigastric upset, takes Drug therapy of the present invention one week, after treatment, patient conscious gastral cavilty portion pain obviously reduces, appetite is normal, and after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 3: Mr. Shi, 35 years old, medical history: patient main suit's gastral cavilty portion pain one week, vexed with painful abdominal mass, belch, pantothenic acid, noisy, feel sick, take Drug therapy of the present invention one week, after treatment, the symptom such as patient conscious gastral cavilty portion pain obviously reduces, and after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 4: Mr. Luo, 42 years old, medical history: patient main suit's epigastrium pain companion acid regurgitation is felt sick 2 days, tending to vomit, melena, diarrhoea and tenesmus, be diagnosed as gastritis, take Drug therapy of the present invention one week, after treatment, patient's conscious abdominal pain companion acid regurgitation is nauseating obviously reduces, after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 5: Mrs Xing, 50 years old, medical history: patient main suit is abdominal distention repeatedly, suffer from abdominal pain half a year, increase the weight of one week, more than outbreak half an hour after meal, companion feels sick, and vomiting, recently goes up disease and increase the weight of gradually, come here to see a doctor, take Drug therapy of the present invention one week, after treatment, the conscious abdominal distention of patient, stomachache obviously reduce, and appetite is normal, after taking three courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 6: Mr. Liu, 59 years old, medical history: patient is conscious epigastric discomfort before first quarter moon, poor appetite, conscious feeling of repletion, the nauseating heartburn companion's pantothenic acid once in a while of companion, the light tenderness of epigastrium, slightly firmly, without vomiting, two is just normal, take Drug therapy of the present invention one week, after treatment, the conscious heartburn companion's pantothenic acid of feeling sick of patient obviously reduces, and appetite is normal, after taking three courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Clinical data
Physical data: gastritis sufferer 50 example, wherein man 29 example, female 21 example, the age be 20-65 year.
Diagnostic criteria: 1. have feed chemistry, physical stimulation thing and contain microorganism, bacteriotoxic food history, often falling ill in 24 hours; 2. have the symptoms such as epigastric discomfort, pain, Nausea and vomiting, several cases can have heating, dehydration, acidosis, even suffers a shock, and erosive gastritis often has upper gastrointestinal hemorrhage; 3. abdominal part or all tenderness of umbilicus is had; 4. visible gastric mucosa hyperemia, edema, secretions increase under gastroscope, or the phenomenon such as hemorrhage erosion.
Therapeutic Method: take Chinese medicine oral liquid of the present invention, every day 2 times, each 30ml one week is a course for the treatment of.
Curative effect determinate standard: recovery from illness: clinical symptoms all disappears, year gastroscope check drug withdrawal later six months to one has no any pathologic and changes: effectively: clinical symptoms all disappears, and after drug withdrawal half a year, gastroscope check pathological change is tending towards curing; Invalid: though clinical symptoms is improved, gastroscope shows that pathological change is without being clearly better.
Therapeutic outcome: by this side treatment gastritis sufferer 50 example, wherein clinical recovery 47 example, effective 3 examples, invalid 0 example, total effective rate is 100%.
Detailed description of the invention
Embodiment 1
The present invention treats the preparation of gastritis Chinese medicine oral liquid, and the weight portion of each raw material is: Radix Bupleuri 15 parts, Fructus Aurantii 12 parts, Herba Eupatorii 18 parts, Flos Rosae Rugosae 15 parts, Rhizoma Et Radix Notopterygii 15 parts, Herba Taraxaci 23 parts, Cortex Magnoliae Officinalis 18 parts, Fructus Amomi Rotundus 13 parts, Rhizoma Acori Graminei 13 parts, 12 parts, Lignum Santali Albi, the Rhizoma Atractylodis Macrocephalae 18 parts, Caulis Perillae 12 parts, Radix Curcumae 18 parts, 13 parts, Poria;
Be prepared from by following methods:
(1) raw material Radix Bupleuri, Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, 10-20 order is ground into after oven dry, for subsequent use;
(2) get raw material Flos Rosae Rugosae, Herba Taraxaci cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, is ground into 10-20 order after oven dry, for subsequent use;
(3) Radix Bupleuri after pulverizing in step (1), Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria are put into machine for decocting Chinese traditional herb medicines, soak 10-20min, amount of water is 8-12 times of above-mentioned raw materials gross weight, decoct under 60-100 DEG C of condition, time is 1-3h, then filter, obtain filtrate and medicinal residues; Flos Rosae Rugosae after pulverizing in step (2), Herba Taraxaci are put into machine for decocting Chinese traditional herb medicines and soaked 10-20min, and amount of water is 8-12 times of above-mentioned raw materials gross weight, decocts under 60-100 DEG C of condition, time is 1-3h, then filters, and obtains filtrate and medicinal residues, after being merged by twice medicinal residues, amount of water is 5-10 times of medicinal residues gross weight, and decoct under 60-100 DEG C of condition, the time is 10-30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, and revolution 10000-28000r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of gastritis.
Usage: oral, every day 2 times, each 30ml.
Embodiment 2
The present invention treats the preparation of gastritis Chinese medicine oral liquid, and the weight portion of each raw material is: Radix Bupleuri 12 parts, Fructus Aurantii 9 parts, Herba Eupatorii 15 parts, Flos Rosae Rugosae 12 parts, Rhizoma Et Radix Notopterygii 12 parts, Herba Taraxaci 20 parts, Cortex Magnoliae Officinalis 15 parts, Fructus Amomi Rotundus 10 parts, Rhizoma Acori Graminei 10 parts, 9 parts, Lignum Santali Albi, the Rhizoma Atractylodis Macrocephalae 15 parts, Caulis Perillae 9 parts, Radix Curcumae 15 parts, 10 parts, Poria;
Be prepared from by following methods:
(1) raw material Radix Bupleuri, Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, 10-20 order is ground into after oven dry, for subsequent use;
(2) get raw material Flos Rosae Rugosae, Herba Taraxaci cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, is ground into 10-20 order after oven dry, for subsequent use;
(3) Radix Bupleuri after pulverizing in step (1), Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria are put into machine for decocting Chinese traditional herb medicines, soak 10-20min, amount of water is 8-12 times of above-mentioned raw materials gross weight, decoct under 60-100 DEG C of condition, time is 1-3h, then filter, obtain filtrate and medicinal residues; Flos Rosae Rugosae after pulverizing in step (2), Herba Taraxaci are put into machine for decocting Chinese traditional herb medicines and soaked 10-20min, and amount of water is 8-12 times of above-mentioned raw materials gross weight, decocts under 60-100 DEG C of condition, time is 1-3h, then filters, and obtains filtrate and medicinal residues, after being merged by twice medicinal residues, amount of water is 5-10 times of medicinal residues gross weight, and decoct under 60-100 DEG C of condition, the time is 10-30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, and revolution 10000-28000r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of gastritis.
Usage: oral, every day 2 times, each 30ml.
Embodiment 3
The present invention treats the preparation of gastritis Chinese medicine oral liquid, and the weight portion of each raw material is: Radix Bupleuri 9 parts, Fructus Aurantii 6 parts, Herba Eupatorii 12 parts, Flos Rosae Rugosae 9 parts, Rhizoma Et Radix Notopterygii 9 parts, Herba Taraxaci 17 parts, Cortex Magnoliae Officinalis 12 parts, Fructus Amomi Rotundus 7 parts, Rhizoma Acori Graminei 7 parts, 6 parts, Lignum Santali Albi, the Rhizoma Atractylodis Macrocephalae 9 parts, Caulis Perillae 6 parts, Radix Curcumae 12 parts, 7 parts, Poria;
Be prepared from by following methods:
(1) raw material Radix Bupleuri, Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, 10-20 order is ground into after oven dry, for subsequent use;
(2) get raw material Flos Rosae Rugosae, Herba Taraxaci cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, is ground into 10-20 order after oven dry, for subsequent use;
(3) Radix Bupleuri after pulverizing in step (1), Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria are put into machine for decocting Chinese traditional herb medicines, soak 10-20min, amount of water is 8-12 times of above-mentioned raw materials gross weight, decoct under 60-100 DEG C of condition, time is 1-3h, then filter, obtain filtrate and medicinal residues; Flos Rosae Rugosae after pulverizing in step (2), Herba Taraxaci are put into machine for decocting Chinese traditional herb medicines and soaked 10-20min, and amount of water is 8-12 times of above-mentioned raw materials gross weight, decocts under 60-100 DEG C of condition, time is 1-3h, then filters, and obtains filtrate and medicinal residues, after being merged by twice medicinal residues, amount of water is 5-10 times of medicinal residues gross weight, and decoct under 60-100 DEG C of condition, the time is 10-30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, and revolution 10000-28000r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of gastritis.
Usage: oral, every day 2 times, each 30ml.
Embodiment 4
The present invention treats the preparation of gastritis Chinese medicine oral liquid, and the weight portion of each raw material is: Radix Bupleuri 11 parts, Fructus Aurantii 8 parts, Herba Eupatorii 14 parts, Flos Rosae Rugosae 11 parts, Rhizoma Et Radix Notopterygii 11 parts, Herba Taraxaci 19 parts, Cortex Magnoliae Officinalis 14 parts, Fructus Amomi Rotundus 9 parts, Rhizoma Acori Graminei 9 parts, 8 parts, Lignum Santali Albi, the Rhizoma Atractylodis Macrocephalae 14 parts, Caulis Perillae 8 parts, Radix Curcumae 14 parts, 11 parts, Poria;
Be prepared from by following methods:
(1) raw material Radix Bupleuri, Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, 10-20 order is ground into after oven dry, for subsequent use;
(2) get raw material Flos Rosae Rugosae, Herba Taraxaci cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, is ground into 10-20 order after oven dry, for subsequent use;
(3) Radix Bupleuri after pulverizing in step (1), Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria are put into machine for decocting Chinese traditional herb medicines, soak 10-20min, amount of water is 8-12 times of above-mentioned raw materials gross weight, decoct under 60-100 DEG C of condition, time is 1-3h, then filter, obtain filtrate and medicinal residues; Flos Rosae Rugosae after pulverizing in step (2), Herba Taraxaci are put into machine for decocting Chinese traditional herb medicines and soaked 10-20min, and amount of water is 8-12 times of above-mentioned raw materials gross weight, decocts under 60-100 DEG C of condition, time is 1-3h, then filters, and obtains filtrate and medicinal residues, after being merged by twice medicinal residues, amount of water is 5-10 times of medicinal residues gross weight, and decoct under 60-100 DEG C of condition, the time is 10-30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, and revolution 10000-28000r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of gastritis.
Usage: oral, every day 2 times, each 30ml.

Claims (7)

1. treat a Chinese medicine oral liquid for gastritis, it is characterized in that: be made up of following raw material: Radix Bupleuri 9-15 part, Fructus Aurantii 6-12 part, Herba Eupatorii 12-18 part, Flos Rosae Rugosae 9-15 part, Rhizoma Et Radix Notopterygii 9-15 part, Herba Taraxaci 17-23 part, Cortex Magnoliae Officinalis 12-18 part, Fructus Amomi Rotundus 7-13 part, Rhizoma Acori Graminei 7-13 part, Lignum Santali Albi 6-12 part, Rhizoma Atractylodis Macrocephalae 9-18 part, Caulis Perillae 6-12 part, Radix Curcumae 12-18 part, Poria 7-13 part.
2. a kind of Chinese medicine oral liquid for the treatment of gastritis according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Bupleuri 12 parts, Fructus Aurantii 9 parts, Herba Eupatorii 15 parts, Flos Rosae Rugosae 12 parts, Rhizoma Et Radix Notopterygii 12 parts, Herba Taraxaci 20 parts, Cortex Magnoliae Officinalis 15 parts, Fructus Amomi Rotundus 10 parts, Rhizoma Acori Graminei 10 parts, 9 parts, Lignum Santali Albi, the Rhizoma Atractylodis Macrocephalae 15 parts, Caulis Perillae 9 parts, Radix Curcumae 15 parts, 10 parts, Poria.
3. a kind of Chinese medicine oral liquid for the treatment of gastritis according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Bupleuri 11 parts, Fructus Aurantii 8 parts, Herba Eupatorii 14 parts, Flos Rosae Rugosae 11 parts, Rhizoma Et Radix Notopterygii 11 parts, Herba Taraxaci 19 parts, Cortex Magnoliae Officinalis 14 parts, Fructus Amomi Rotundus 9 parts, Rhizoma Acori Graminei 9 parts, 8 parts, Lignum Santali Albi, the Rhizoma Atractylodis Macrocephalae 14 parts, Caulis Perillae 8 parts, Radix Curcumae 14 parts, 11 parts, Poria.
4. a kind of Chinese medicine oral liquid for the treatment of gastritis according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Bupleuri 15 parts, Fructus Aurantii 12 parts, Herba Eupatorii 18 parts, Flos Rosae Rugosae 15 parts, Rhizoma Et Radix Notopterygii 15 parts, Herba Taraxaci 23 parts, Cortex Magnoliae Officinalis 18 parts, Fructus Amomi Rotundus 13 parts, Rhizoma Acori Graminei 13 parts, 12 parts, Lignum Santali Albi, the Rhizoma Atractylodis Macrocephalae 18 parts, Caulis Perillae 12 parts, Radix Curcumae 18 parts, 13 parts, Poria.
5. a kind of Chinese medicine oral liquid for the treatment of gastritis according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Bupleuri 9 parts, Fructus Aurantii 6 parts, Herba Eupatorii 12 parts, Flos Rosae Rugosae 9 parts, Rhizoma Et Radix Notopterygii 9 parts, Herba Taraxaci 17 parts, Cortex Magnoliae Officinalis 12 parts, Fructus Amomi Rotundus 7 parts, Rhizoma Acori Graminei 7 parts, 6 parts, Lignum Santali Albi, the Rhizoma Atractylodis Macrocephalae 9 parts, Caulis Perillae 6 parts, Radix Curcumae 12 parts, 7 parts, Poria.
6. a kind of preparation method for the treatment of the Chinese medicine oral liquid of gastritis according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) raw material Radix Bupleuri, Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, 10-20 order is ground into after oven dry, for subsequent use;
(2) get raw material Flos Rosae Rugosae, Herba Taraxaci cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, is ground into 10-20 order after oven dry, for subsequent use;
(3) Radix Bupleuri after pulverizing in step (1), Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria are put into machine for decocting Chinese traditional herb medicines, soak 15min, amount of water is 8-12 times of above-mentioned raw materials gross weight, decoct under 60-100 DEG C of condition, time is 1-3h, then filter, obtain filtrate and medicinal residues; Flos Rosae Rugosae after pulverizing in step (2), Herba Taraxaci are put into machine for decocting Chinese traditional herb medicines and soaked 10-20min, and amount of water is 8-12 times of above-mentioned raw materials gross weight, decocts under 60-100 DEG C of condition, time is 1-3h, then filters, and obtains filtrate and medicinal residues, after being merged by twice medicinal residues, amount of water is 5-10 times of medicinal residues gross weight, and decoct under 60-100 DEG C of condition, the time is 10-30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, and revolution 10000-28000r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of gastritis.
7. a kind of preparation method for the treatment of the Chinese medicine oral liquid of gastritis according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) raw material Radix Bupleuri, Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2m/s, and drying time is 1h, 20 orders are ground into after oven dry, for subsequent use;
(2) get raw material Flos Rosae Rugosae, Herba Taraxaci cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2m/s, and drying time is 1h, is ground into 20 orders after oven dry, for subsequent use;
(3) Radix Bupleuri after pulverizing in step (1), Herba Eupatorii, Fructus Aurantii, Rhizoma Et Radix Notopterygii, Cortex Magnoliae Officinalis, Rhizoma Acori Graminei, the Rhizoma Atractylodis Macrocephalae, Lignum Santali Albi, Caulis Perillae, Radix Curcumae, Fructus Amomi Rotundus, Poria are put into machine for decocting Chinese traditional herb medicines, soak 20min, amount of water is 12 times of above-mentioned raw materials gross weight, decoct under 83 DEG C of conditions, time is 1h, then filter, obtain filtrate and medicinal residues; Flos Rosae Rugosae after pulverizing in step (2), Herba Taraxaci are put into machine for decocting Chinese traditional herb medicines and soaked 20min, and amount of water is 12 times of above-mentioned raw materials gross weight, decocts under 83 DEG C of conditions, time is 1h, then filters, and obtains filtrate and medicinal residues, twice medicinal residues is merged 10 times that amount of water is above-mentioned raw materials gross weight, and decoct under 75 DEG C of conditions, the time is 30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 105mm, and revolution 16500r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.2 μm, and pressure is 0.05MPa, and crossflow velocity is 4m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, when being evaporated to 60 DEG C in concentration tank, the clear paste of relative density 1.08, obtains clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 83 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100 DEG C, time is 15min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of gastritis.
CN201510755147.6A 2015-11-09 2015-11-09 Traditional Chinese medicinal oral solution for treating gastritis and preparation method of traditional Chinese medicinal oral solution Pending CN105194582A (en)

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