CN105663343A - Traditional Chinese medicine compound preparation for treating gynecological chronic pelvic inflammatory disease - Google Patents
Traditional Chinese medicine compound preparation for treating gynecological chronic pelvic inflammatory disease Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
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Abstract
The invention discloses a traditional Chinese medicine compound preparation for treating gynecological chronic pelvic inflammatory disease. The traditional Chinese medicine compound preparation is characterized by, proportionally weighing, by weight, 70-90 g of Radix Astragali, 15-25 g of Radix Angelicae Sinensis, 5-15 g of Rhizoma Chuanxiong, 15-25 g of Radix Paeoniae Alba(stir-fried), 25-25 g of Fructus Forsythiae, 15-25 g of Flos Lonicerae, 15-25 g of herba taraxaci, 5-15 g of Radix Morindae Officinalis, 5-15 g of Herba Epimedii, 10-20 g of Rhizoma Corydalis and 5-15 g of Radix Glycyrrhizae Preparata, mixing the Chinese medicinal herbs uniformly, grinding and screening by sieves with 60-100 meshes to obtain traditional Chinese medicine powder, and sterilizing the traditional Chinese medicine powder to obtain the compound preparation; further, packing the traditional Chinese medicine powder into capsules which are 0.5g per capsule in specification. The traditional Chinese medicine compound preparation has the advantages of combining tonification and purgation, treating both qi and blood, balancing cold and heat, replenishing yin and yang, and the like.
Description
Technical field
The present invention relates to Chinese medicine, specifically a kind of compound preparation treating women's chronic pelvic inflammation.
Background technology
Chronic pelvic inflammatory disease is one of modal chronic disease of gynecological, and main clinical manifestation is hypogastric region falling inflation pain or lumbosacral region distending pain, is often accompanied by low grade fever, tired, leucorrhoea grow in quantity, menoxenia or infertile etc. Primary disease is the disease that a kind of course of disease is longer, the normal recurrent exerbation of the state of an illness, the feature easily recurred after having course of disease delay, fatigue. Long-term chronic pelvic pain, often may result in patient and produces anxiety, depression, thus affecting work, family life, women's physical and mental health is totally unfavorable. Therefore relevant expert claims chronic pelvic inflammatory disease to be the new challenge to WomanHealth in this century.
Chronic pelvic inflammatory disease be there is no desirable Therapeutic Method, single antibiotic unsatisfactory curative effect, easy drug resistance by current doctor trained in Western medicine, and because of pelvic cavity chronic inflammatory focus adhesion, blood circulation is poor, and antibiotic is difficult to reach valid density, add drug resistance incidence rate, make the state of an illness obstinate and recurrent exerbation. Seek curative effect height, medicine easy to use, be a difficult problem in treatment. Treatment by Chinese herbs chronic pelvic inflammatory disease, has instant effect, curative effect is comprehensive, late result is a good advantage. In the higher medical institution undergraduate course state-compiled textbook of the doctor trained in Western medicine department of obstetrics and gynecology whole nation, chronic pelvic inflammatory disease is unique disease that Chinese medicine is classified as first-selected method for the treatment of, it is sufficient to the advantage of visible Chinese medicine primary disease is by everybody accreditation. Treat the Chinese patent medicine of chronic pelvic inflammatory disease in the market mostly based on the Chinese medicine of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, but if life-time service, with the passing of time will produce the negative effect because using the cold and cool medicines such as heat-clearing and toxic substances removing to bring. Prolonged illness then body is impaired, internal organs deficient qi and blood, wherein basic for it to suffer from a deficiency of the kidney, therefore patient is often because of positive QI-insufficiency, causes the situation that medicine does not remove to disease. With the passing of time undergoing chronic pelvic inflammation must cause positive exogenous pathogen and contain, simulataneous insufficiency and excessive.
Summary of the invention
Present invention aim to address above-mentioned the deficiencies in the prior art, there is provided a kind of according to the basis of clinical observation for many years, select the Chinese medicine with inrigorating qi and promoting blood circulation, kidney-reinforcing Yang strengthening, heat-clearing and toxic substances removing, dispersing cold for relieving pain through clinical repeated screening, and there is reinforcement and elimination in combination, QI and blood is ruled together, coordination of cold and heat, flat nourishing YIN sun, fully demonstrate blood stasis dispelling and just do not hinder, righting and do not hold back heresy, deficiency and excess, QI and blood, cold and heat take into account compatibility treatment women's chronic pelvic inflammation compound preparation.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of compound Chinese medicinal preparation treating women's chronic pelvic inflammation, it is characterized in that the raw material medicaments in part by weight proportioning of Chinese medicine is Radix Astragali 70-90g, Radix Angelicae Sinensis 15-25g, Rhizoma Chuanxiong 5-15g, Radix Paeoniae Alba (parched) 15-25g, Fructus Forsythiae 25-25g, Flos Lonicerae 15-25g, Herba Taraxaci 15-25g, Radix Morindae Officinalis 5-15g, Herba Epimedii 5-15g, Rhizoma Corydalis 10-20g and Radix Glycyrrhizae Preparata 5-15g, by above-mentioned all medicines with together with mix homogeneously, pulverized 60-100 mesh sieve, it is compound preparation after being ground into the Chinese medicine powder sterilizing of smalls, again Chinese medicinal powder is loaded capsule, every capsules 0.5 gram, share by the Radix Astragali and Radix Angelicae Sinensis two medicine, energy qi-supplementing, blood-engendering, righting training is first, to treat disease caused QI and blood consumption wound for a long time, deficiency of QI in middle-JIAO, also can treat because of deficiency of vital energy inability of body fluid to function, water wets the profuse leukorrhea that causes of bet,By Rhizoma Chuanxiong and Radix Angelicae Sinensis compatibility, promoting blood circulation to remove blood stasis can be strengthened, effect of promoting the circulation of QI to relieve pain; Compatible by Radix Paeoniae Alba (parched) and Radix Angelicae Sinensis, Rhizoma Chuanxiong, there is effect of nourishing blood for regulating menstruation; By Fructus Forsythiae and Flos Lonicerae, the use of Herba Taraxaci compatibility, playing effect of heat-clearing and toxic substances removing altogether, treating fights to tie because of damp and hot remaining evil and QI and blood rushes the few abdomen pain appointed caused by uterus, controls with clearing away heat and cooling blood, in case stasis of blood heat-transformation of a specified duration; Share by Radix Morindae Officinalis and Herba Epimedii, there is kidney invigorating and YANG supporting, effect of expelling wind and removing dampness, Papillary kidney-reinforcing Yang strengthening; The traditional Chinese medical science says qi being the governor of blood, gas row then blood, and the stagnation of QI is blood stasis then, therefore helps again with Rhizoma Corydalis, can invigorate blood circulation, again can circulation of qi promoting, there is good analgesic efficacy, above-mentioned all medicines are in harmonious proportion by Radix Glycyrrhizae Preparata, significantly improve effect of replenishing QI to invigorate the spleen.
The present invention can add Radix Aconiti Lateralis Preparata 5-15g, Cortex Cinnamomi 10-15g, Fructus Foeniculi 10-15g and Rhizoma Zingiberis Preparatum 20-25g by weight ratio in the crude drug of above-mentioned Chinese medicine, by being equipped with Radix Aconiti Lateralis Preparata, Cortex Cinnamomi, Fructus Foeniculi and Rhizoma Zingiberis Preparatum, supporing yang to reach benefit fire, dispersing cold for relieving pain, effect of promoting the flow of QI-blood by warming the meridian.
The present invention can add Radix Linderae 10-20g by weight ratio in the crude drug of above-mentioned Chinese medicine, to reach effect of promoting the circulation of QI to relieve pain, warming kidney for dispelling cold.
Instructions of taking: the drug dose that every day is administered orally is 5 grams, every bu is administered orally for early, middle and late three times, each 3.
Due to the fact that employing said structure, there is reinforcement and elimination in combination, QI and blood is ruled together, coordination of cold and heat, flat nourishing YIN sun etc. advantage.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further described:
Preferred embodiment: a kind of compound Chinese medicinal preparation treating women's chronic pelvic inflammation, the raw material medicaments in part by weight proportioning of its Chinese medicine is Radix Astragali 80g, Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 10g, Flos Lonicerae 20g, Fructus Forsythiae 20g, Herba Taraxaci 20g, Rhizoma Zingiberis Preparatum 15g, Rhizoma Corydalis 15g, Radix Paeoniae Alba (parched) 20g, Fructus Foeniculi 15g, Cortex Cinnamomi 15g, Radix Aconiti Lateralis Preparata 10g, Radix Linderae 15g, Herba Epimedii 10g, Radix Morindae Officinalis 10g, Radix Glycyrrhizae Preparata 10g. , by above-mentioned all medicines with together with mix homogeneously, pulverized 60-100 mesh sieve, and after being ground into the Chinese medicine powder sterilizing of smalls, be compound preparation, then Chinese medicinal powder is loaded capsule, every capsules 0.5 gram.
Instructions of taking: the drug dose that every day is administered orally is 5 grams, every bu is administered orally for early, middle and late three times, each 3.
The prescription solution of the present invention:
The Radix Astragali, sweet in the mouth, tepor, return spleen, lung meridian, there is effect of tonifying Qi and lifting yang, for the key medicine of QI invigorating. Radix Angelicae Sinensis sweet in the mouth is pungent, warm in nature, returns liver heart spleen channel, have enrich blood, invigorate blood circulation, effect of pain relieving, it is adaptable to the various syndromes that blood deficiency causes, can replenishing and activating blood, kind pain relieving, is Fuke Tiaojing key medicine again, and the Radix Astragali and Radix Angelicae Sinensis two medicine share, energy qi-supplementing, blood-engendering, righting training is first, to treat disease caused QI and blood consumption wound, deficiency of QI in middle-JIAO for a long time, also can treating because of deficiency of vital energy inability of body fluid to function, water wets the profuse leukorrhea that causes of bet. Rhizoma Chuanxiong, acrid in the mouth, warm in nature, return liver and gall, pericardium channel. There is effect of blood-activating and qi-promoting pain relieving, can temperature promoting blood circulation, can blood circulation promoting and blood stasis dispelling, again can activating QI to alleviate the depression pain relieving, for the gas medicine in blood, and Radix Angelicae Sinensis compatibility, promoting blood circulation to remove blood stasis can be strengthened, effect of promoting the circulation of QI to relieve pain. The Radix Paeoniae Alba, bitter in the mouth acid, cold nature, return liver spleen channel, compatible with Radix Angelicae Sinensis, Rhizoma Chuanxiong, there is effect of nourishing blood for regulating menstruation. Fructus Forsythiae, lightly seasoned, micro-hardship, cool in nature, merit is apt to heat-clearing and toxic substances removing, mass dissipating and swelling eliminating, and Li Gao calls this product " dissipating all menses stagnation of QI to gather, detumescence ". With effect that heat-clearing and toxic substances removing is played in Flos Lonicerae, the use of Herba Taraxaci compatibility altogether, treatment is fought to tie because of damp and hot remaining evil and QI and blood and is rushed the few abdomen pain appointed caused by uterus, controls with clearing away heat and cooling blood, in case stasis of blood heat-transformation of a specified duration, Radix Morindae Officinalis is pungent sweet, and slightly warm in nature has effect of reinforcing the kidney and supporting YANG.Herba Epimedii has kidney invigorating and YANG supporting, effect of expelling wind and removing dampness, Papillary kidney-reinforcing Yang strengthening. Qi being the governor of blood, gas row then blood, the stagnation of QI is blood stasis then, therefore helps again with Rhizoma Corydalis, can invigorate blood circulation, again can circulation of qi promoting, there is good analgesic efficacy. Radix Aconiti Lateralis Preparata, is good at mending fire supporing yang, dispersing cold for relieving pain. Be equipped with Cortex Cinnamomi, that Fructus Foeniculi, Rhizoma Zingiberis Preparatum can mend fire is supporing yang, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian. The Radix Linderae, promoting the circulation of QI to relieve pain, warming kidney for dispelling cold. Radix Glycyrrhizae, replenishing QI to invigorate the spleen, coordinating the actions of various ingredients in a prescription, for making medicine.
We's residence is attacked in benefit, tonification involving purgation, reinforcement and elimination in combination, plays the merit of inrigorating qi and promoting blood circulation, kidney-reinforcing Yang strengthening altogether; All medicines share, flat nourishing YIN sun, QI and blood is ruled together, coordination of cold and heat, reinforcement and elimination in combination, makes we fully demonstrate righting and does not hold back heresy, blood stasis dispelling and just do not hinder, the compatible experiments that deficiency and excess, QI and blood, cold and heat are taken into account. The present invention be this common gynecological disease of chronic pelvic inflammatory disease provide that a kind of curative effect is high, effect is complete, non-evident effect and contraindication, the good medicine of taking convenience. Clinically deeply by the welcome of extensive patients, it is worth of widely use.
The clinical efficacy for the treatment of chronic pelvic inflammatory disease is summed up:
One, physical data
Through 60 example clinical treatments, according to including case standard and Excluded cases standard in, collect 60 example patients altogether and make
For observing case. Being randomly divided into treatment group and matched group, often organize each 30 example patients, the age of two groups of patients, fertility condition, the course of disease, severity extent comparing difference, without significance, have comparability.
Two, diagnostic criteria
(1) medical history: have acute pelvic inflammatory disease medical history more.
(2) symptom: lower abdomen and lumbago, lower abdomen falling inflation, lumbosacral region is ached, after fatigue of being everlasting, sexual intercourse, defecation time and menstruation before and after increase the weight of. Can increase and leucorrhoea grow in quantity with low grade fever, menstruation.
(3) sign: Chang Chenghou position, uterus, limitation of activity or adhesion are fixed; Touch streak thing in one or both sides, uterus during salpingitis, and have mild tenderness; Or touch enclosed mass in one or both sides, uterus.
(4) auxiliary examination
1. routine blood test: if there being inflammatory masses and masses to be formed, can have leukocyte or neutrophilic granulocyte slightly to increase.
2. ultrasound diagnosis: can visit and adnexa inflammatory masses and masses, fallopian tube increase thick or hydrops.
Three, method of administration
Treatment group takes invention formulation, each 3, every day 3 times. It is each that matched group takes FUKE QIANJIN PIAN
6, every day 3 times. Two groups of patients all further consultation after taking medicine 28 days, drug withdrawals in menstrual period.
Four, curative effect determinate standard
Comprehensive therapeutic effect criterion is with reference to " the clinical guidance principle of new Chinese medicine treatment female genital disease "
The curative effect determinate standard formulating chronic pelvic inflammatory disease is as follows: recovery from illness: symptom, sign and inspection all recover normal, and integration is 0. Effective: transference cure, gynecologial examination has clear improvement, and reduces by more than 2/3 than integration before treatment after treatment. Effective: symptom, sign and check all have and alleviate, reduce by more than 1/3 than integration before treatment after treatment. Invalid: without improving after treatment.
Five, therapeutic effect
Taking the treatment group lower abdomen pendant pain twinge of Chinese medicine preparation of the present invention, lumbosacral aching pain and profuse leukorrhea symptom to be obviously improved, difference has significance (P < 0.05) compared with matched group. Clinical efficacy: treatment group (takes this preparation) and matched group (taking FUKE QIANJIN PIAN) total effective rate respectively 96.67%, 76.67%; Treatment group and matched group tcm syndrome total effective rate respectively 96.67%, 76.67%, treatment group is evident in efficacy is better than matched group.
Six, model case
Zhao, female, 27 years old, 2 years after marriage, uncomfortable 1 year of inferior belly gas pain, with Right Lower Abdomen for very, suffering from abdominal pain as holding
Continuous property, afternoon and evening is heavier, and companion's lower back is uncomfortable.Do not practise contraception unpregnancy always. B ultrasonic prompting right side fallopian tube internal diameter 1.5 centimetres, it is considered to right side hydrosalpinx. Gynecologial examination: retroposition of uterus, limitation of activity, light tenderness, ride side attachment touches streak thing, hence it is evident that tenderness. Diagnosis is chronic pelvic inflammatory disease, with right side hydrosalpinx. Patient takes invention formulation, each 3, every day 3 times, drug withdrawal in menstrual period, and after taking 3 months, colic symptoms disappears, conceived after half a year.
2. Korea Spro so-and-so, female, 35 years old, chronic intermittent lower abdominal pain 3 years, increase the weight of one month. Eumenorrhea, patient's private prosecution is in the period be lower abdomen not bitterly, lower abdominal pain after menstruation, especially anus pendant pain is substantially, once in multiple hospitals diagnosis and treatment, all without obvious curative effects. Having a medical check-up: vagina is smooth, and cervix uteri is smooth, retroversio flexio, normal size, during pressing palace body, anus pendant pain increases the weight of, it is impossible to stand, double accessory no abnormality seen. Patient is without operation on pelvis medical history. Color ultrasound shows a small amount of hydrops of pelvic cavity. Diagnosis is chronic pelvic inflammatory disease. After taking invention formulation 1 month, stomachache alleviates, anus pendant pain transference cure.
3, Ma, female, 32 years old, lower abdominal pain after medicine stream, accompany the soreness of waist, recurrent exerbation 2 years, tired postemphasis, weak, low grade fever, Hypomenorrhea, color is dark. B ultrasonic shows: a small amount of hydrops of pelvic cavity. Gynecologial examination: retroposition of uterus, normal in size, tenderness is obvious, and bilateral adnexa thickens, tenderness. Taking 2 months stomachache of invention formulation to disappear, menstrual blood volume is normal, and weak and soreness of waist symptom improves.
Claims (3)
1. the compound Chinese medicinal preparation treating women's chronic pelvic inflammation, it is characterized in that the raw material medicaments in part by weight proportioning of Chinese medicine is Radix Astragali 70-90g, Radix Angelicae Sinensis 15-25g, Rhizoma Chuanxiong 5-15g, Radix Paeoniae Alba (parched) 15-25g, Fructus Forsythiae 25-25g, Flos Lonicerae 15-25g, Herba Taraxaci 15-25g, Radix Morindae Officinalis 5-15g, Herba Epimedii 5-15g, Rhizoma Corydalis 10-20g and Radix Glycyrrhizae Preparata 5-15g, by above-mentioned all medicines with together with mix homogeneously, pulverize 60-100 mesh sieve, after being ground into the Chinese medicine powder sterilizing of smalls, be compound preparation.
2. a kind of compound Chinese medicinal preparation treating women's chronic pelvic inflammation according to claim 1, it is characterized in that in the crude drug of Chinese medicine by weight ratio for Radix Astragali 70-90g, Radix Angelicae Sinensis 15-25g, Rhizoma Chuanxiong 5-15g, Radix Paeoniae Alba (parched) 15-25g, Fructus Forsythiae 25-25g, Flos Lonicerae 15-25g, Herba Taraxaci 15-25g, Radix Morindae Officinalis 5-15g, Herba Epimedii 5-15g, Rhizoma Corydalis 10-20g, Radix Glycyrrhizae Preparata 5-15g, Radix Aconiti Lateralis Preparata 5-15g, Cortex Cinnamomi 10-15g, Fructus Foeniculi 10-15g and Rhizoma Zingiberis Preparatum 20-25g, by above-mentioned all medicines with together with mix homogeneously, pulverized 60-100 mesh sieve, it is compound preparation after being ground into the Chinese medicine powder sterilizing of smalls.
3. a kind of compound Chinese medicinal preparation treating women's chronic pelvic inflammation according to claim 2, it is characterized in that in the crude drug of Chinese medicine by weight ratio for Radix Astragali 70-90g, Radix Angelicae Sinensis 15-25g, Rhizoma Chuanxiong 5-15g, Radix Paeoniae Alba (parched) 15-25g, Fructus Forsythiae 25-25g, Flos Lonicerae 15-25g, Herba Taraxaci 15-25g, Radix Morindae Officinalis 5-15g, Herba Epimedii 5-15g, Rhizoma Corydalis 10-20g, Radix Glycyrrhizae Preparata 5-15g, Radix Aconiti Lateralis Preparata 5-15g, Cortex Cinnamomi 10-15g, Fructus Foeniculi 10-15g, Rhizoma Zingiberis Preparatum 20-25g and Radix Linderae 10-20g, by above-mentioned all medicines with together with mix homogeneously, pulverized 60-100 mesh sieve, it is compound preparation after being ground into the Chinese medicine powder sterilizing of smalls.
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CN106389566A (en) * | 2016-08-08 | 2017-02-15 | 青岛友诚高新技术有限公司 | Traditional Chinese medicine composition for curing pelvic inflammation and preparation method thereof |
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CN1356123A (en) * | 2001-08-16 | 2002-07-03 | 赵西铭 | Medicine for treating female acyesis |
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