CN104013921A - Medicament composition for treating gastric ulcer and adjusting digestive functions - Google Patents
Medicament composition for treating gastric ulcer and adjusting digestive functions Download PDFInfo
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- CN104013921A CN104013921A CN201410296677.4A CN201410296677A CN104013921A CN 104013921 A CN104013921 A CN 104013921A CN 201410296677 A CN201410296677 A CN 201410296677A CN 104013921 A CN104013921 A CN 104013921A
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Abstract
The invention discloses a medicament composition for treating gastric ulcer and adjusting digestive functions. The medicament composition comprises the following raw materials in parts by weight: 14-16 parts of pilose asiabell root, 4-6 parts of hawthorn fruit, 4-6 parts of liquoric root, 14-16 parts of Indian buead, 14-16 parts of mongolian dandelion herb, 1-2 parts of golden thread, 14-16 parts of calcined oyster shell, 7-9 parts of perilla stem, 7-9 parts of Sichuan officinal magnolia bark, 2-4 parts of root of rehmannia, 7-9 parts of zedoary, 9-11 parts of common burreed rhizome, 9-11 parts of pseudo-ginseng and 18-20 parts of wild buckwheat rhizome. The medicament composition disclosed by the invention is rigorous in prescription, performs overall recuperation from various levels, various links and various targets, also can be used for adjusting the disordered digestive functions aiming at the main pathogenesis of gastric ulcer, and can be used for improving the healing quality, reducing the recurrence rate of gastric ulcer, and especially reducing the dependence effects on a proton pump inhibitor without causing side or toxic effects.
Description
Technical field
The present invention relates to Chinese medicine composition technical field, relate in particular to a kind of drug regimen that is used for the treatment of gastric ulcer and adjusts digestive function.
Background technology
Gastric ulcer is common clinical and frequently-occurring disease, and often the cause of disease comprises: 1, helicobacter pylori infections; 2, the medicine such as long-term taking aspirin, corticosteroid, or long-term smoking, drinks for a long time and drinks strong tea, coffee; 3, gastric acid/pepsin autodigestion; 4, long-term psychentonia, anxiety or anxious state of mind; 5, inherited genetic factors; 6, stomach dyskinesia.Epigastrium pain is the cardinal symptom of gastric ulcer, also can appear at after left upper abdomen or breastbone, xiphoid-process.Often be dull pain, dull pain, distending pain, burn sample pain.The many appearance in 1 hour after the meal of pain of gastric ulcer are alleviated gradually, until reappear the above-mentioned rhythm and pace of moving things after the feed of lower meal after 1-2h again.Some patients were can be asymptomatic, or using the complication such as hemorrhage, perforation as onset symptoms.Under scope, ulcer can be divided into three stadium: 1. active stage: ulcer basilar part is covered with white or yellow-white thick fur, congested, the edema (A1) of mucosa around, or periphery mucosa is congested, edema starts to disappear, and there is the formed blush of re-epithelialize (A2) in surrounding; 2. healing stage: ulcer is dwindled and shoaled, tongue attenuation, the formed blush of surrounding re-epithelialize is crowded around to ulcer, and duplicature is concentrated (H1) to ulcer, or ulcer surface is almost re-epithelialize and covers, and duplicature is more to ulcer concentrated (H2).3. cicatricial phase: ulcer basilar part white fur disappears, and presents red cicatrix (S1), finally changes white cicatrix (S2) into.
Drug therapy healing in the recent period is at present better, but after drug withdrawal, relapse rate is high, therefore for the treatment of gastric ulcer, should pay attention to improving late result, control recurrence.Gastric ulcer belongs to the category of the traditional Chinese medical science " gastric abscess ", and take knot, qi depression to blood stasis in weakness of the spleen and stomach, pyretic toxicity is main pathogenesis.Have research data to confirm, spleen invigorating heat clearing and blood stasis dispersing Chinese medicine can not only be eliminated the damage factor of ulcer, strengthens gastric mucosal protection factor; and in treatment gastric ulcer; can also adjust disorderly digestive function, improve healing quality, reduce the relapse rate of gastric ulcer.
Summary of the invention
The technical problem that basic background technology exists, the present invention proposes a kind of drug regimen that is used for the treatment of gastric ulcer and adjusts digestive function, prescription is rigorous, from multi-level, too many levels, the whole conditioning of many target spots, for the main pathogenesis of gastric ulcer, can also adjust disorderly digestive function, improve healing quality, reduced the relapse rate of gastric ulcer, particularly reduced proton pump inhibitor dependence effect, have no side effect.
A kind of drug regimen that is used for the treatment of gastric ulcer and adjusts digestive function that the present invention proposes, its raw material comprises by weight: Radix Codonopsis 19-21 part, Fructus Crataegi 4-6 part, Radix Glycyrrhizae 9-11 part, Poria 14-16 part, Herba Taraxaci 14-16 part, Rhizoma Coptidis 1-2 part, Concha Ostreae (calcined) 14-16 part, Caulis Perillae 7-9 part, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China 7-9 part, Radix Rehmanniae 2-4 part, Rhizoma Curcumae 7-9 part, Rhizoma Sparganii 9-11 part, Radix Notoginseng 9-11 part, Rhizoma Fagopyri Dibotryis 18-20 part.
Radix Codonopsis, sweet in the mouth, property is flat, returns spleen, lung meridian.Have invigorating the spleen and replenishing QI, quench the thirst, spleen invigorating lung benefiting, nourishing blood to promote the production of body fluid.Cure mainly weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, lack of appetite is thirsty, chronic diarrhea proctoptosis.This product effect is similar to Radix Ginseng, and only the efficacy of a drug is weak.Control general deficiency syndrome, can replace Radix Ginseng to use; Collapse is card heavily, still with Radix Ginseng, is advisable.Excavate autumn, cleans, and dries.
Fructus Crataegi, sour in the mouth, sweet, slightly warm in nature, enters spleen, stomach, Liver Channel.Have help digestion long-pending, dissipating blood stasis blood, taenifugal effect.Cure mainly meat long-pending, lump in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis etc.For meat stagnation, stomach alkane distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain, hyperlipidemia.
Radix Glycyrrhizae, sweet in the mouth, property is flat, enters spleen, stomach, lung meridian.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, clear throat, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Poria, another name Fu Tu, Poria, Fu Ling, volt Tu,, loose potato, Masson Pine potato, Song Ling etc.Its medicinal part is the sclerotium of On Polyporaceae Poria.Sweet in the mouth, light, property is flat, GUIXIN, spleen, kidney channel.There is promoting diuresis to eliminate damp pathogen, spleen invigorating, the effect of calming the nerves.
Herba Taraxaci, another name Herba crotalariae albidae, grandmother's fourth, Compositae, is a kind of herbaceos perennial.In Herba Taraxaci plant, contain the multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, inulin.Sweet in the mouth, micro-hardship, cold in nature.Return liver, stomach warp.There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.
Rhizoma Coptidis, bitter in the mouth, cold in nature, GUIXIN, stomach, liver, large intestine channel.The effect with heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.
Concha Ostreae is containing calcium carbonate, the calcium phosphate of 80-95%, and < < Chinese Pharmacopoeia > > nineteen ninety-five version is " get clean Concha Ostreae, according to method of direct calcination, be calcined to crisp " to the process of preparing Chinese medicine regulation of Concha Ostreae.The convergence effect astringent or styptic treatment for spontaneous sweating, relieving gastric hyperacidity to alleviate stomachache of Concha Ostreae (calcined) is strong, can be used for that treatment has a stomach-ache, gastric acid etc., can also tranquillization with heavy prescription, and hard masses softening and resolving.
Caulis Perillae is the dry stem of labiate Folium Perillae.Tap after fruit maturation autumn, removes impurity, dries, or take advantage of fresh slices, dries.Acrid in the mouth, warm in nature.Return lung, spleen channel.There is regulating the flow of QI to ease the stomach, pain relieving, antiabortive effect.Vexed for chest and diaphragm painful abdominal mass, gastralgia, belch vomiting, frequent fetal movement.
CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, another name Cortex Magnoliae Officinalis, Cortex Magnoliae Officinalis etc.Bitter in the mouth, pungent, warm in nature.Return spleen, stomach, large intestine channel.There is circulation of qi promoting removing food stagnancy, dampness except effect full, lowering the adverse QI to relieve asthma, cure mainly that stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, gastral cavity painful abdominal mass are vomited and diarrhoea, expectorant is stopped up QI rising in reverse order, fullness in the chest is breathed with cough.Rhizoma Zingiberis makes for it, dislikes Rhizoma Alismatis, Mirabilitum crystallina, Sal Nitri.Avoid bean, the person of food takes offence.Gestation can not take.
The Radix Rehmanniae, sweet in the mouth, cold in nature, GUIXIN, liver, kidney channel, has clearing away heat and cooling blood effect use, and existing anastalsis, has again blood coagulation resisting function, also has antifungic action.
Rhizoma Curcumae, acrid in the mouth, hardship, warm in nature, return liver, spleen channel.Cure mainly removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving, promoting the circulation of QI to relieve pain, removing blood stasis removing food stagnancy, promoting digestion and removing stagnation.Rhizoma Curcumae has the fraud of consumption impairment of QI blood, and Discontinue medication as soon as get effect should not take excessive or for a long time.Miao Xiyong is discussed in < < Bencao Jingshu > >: " the fluffy cowherb circulation of qi promoting removing blood stasis eliminating stagnation that obtains; be the chief of its function; with regard to married woman, children's's QI and blood deficiency; taste element is weak and without stagnant person; the anti-energy loss vital qi of using does not more disappear food and a little less than taste benefit.Have that vim and vigour are condensed, eating accumulation, also when and spleen benefiting and stimulating the appetite, the same use of tonification vigour medicine, be harmless ear.”
Rhizoma Sparganii, acrid in the mouth, puckery, cool in nature, enter liver, spleen channel.There is the effects such as blood stasis dispelling stimulates the menstrual flow, removing blood stasis eliminating mass, circulation of qi promoting removing food stagnancy.Cure mainly lump in the abdomen, gather, distending pain over the hypochondrium, food stagnation distending pain, dysmenorrhea, amenorrhea, postnatal blood stasis stomachache, traumatic injury.
Radix Notoginseng, sweet and slightly bitter taste, warm in nature, enter liver, stomach, large intestine channel; There is hemostasis, dissipating blood stasis, detumescence, analgesic therapy.Control haematemesis, hemoptysis, epistaxis, has blood in stool, dysentery, metrorrhagia, lump in the abdomen, puerperal blood faints, retention of lochia, falls and flutters blood stasis, traumatic hemorrhage, carbuncle pain.
Rhizoma Fagopyri Dibotryis, polygonaceae plant, another name Radix Et Rhizoma Fagopyri Tatarici, wild bridge Semen Fagopyri Esculenti, day Semen Fagopyri Esculenti, main product in Shaanxi, the province such as Jiangsu, Zhejiang, Hubei, Hunan, East China one band also can be cultivated.It is cool in nature, and acrid in the mouth, hardship have the effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, invigorating spleen to remove dampness.
Above raw material, after optimum organization of the present invention, is made the Chinese medicine preparation for the treatment of gastric ulcer, not only can bring into play separately original effect, more can further strengthen its curative effect, treatment gastric ulcer is better than to the effect of existing medicine, also can reduce recurrence.
Preferably, Radix Codonopsis 19.3-20.7 part, Fructus Crataegi 4.2-5.7 part, Radix Glycyrrhizae 9.5-10.5 part, Poria 14.9-15.7 part, Herba Taraxaci 14.6-15.3 part, Rhizoma Coptidis 1.2-1.7 part, Concha Ostreae (calcined) 14.3-15.6 part, Caulis Perillae 7.8-8.3 part, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China 7.3-8.1 part, Radix Rehmanniae 2.2-3.6 part, Rhizoma Curcumae 7.5-8.5 part, Rhizoma Sparganii 9.6-10.2 part, Radix Notoginseng 9.2-10.8 part, Rhizoma Fagopyri Dibotryis 18.6-19.4 part.
Preferably, the weight ratio of Rhizoma Curcumae and Rhizoma Sparganii is 8:10.
Preferably, 20 parts of Radix Codonopsis, 5 parts of Fructus Crataegis, 10 parts, Radix Glycyrrhizae, 15 parts, Poria, 15 parts of Herba Taraxacis, 1.5 parts of Rhizoma Coptidis, 15 parts of Concha Ostreae (calcined)s, 8 parts of Caulis Perillaes, 8 parts of CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, 3 parts, the Radix Rehmanniae, 8 parts of Rhizoma Curcumae, 10 parts of Rhizoma Sparganii, 10 parts of Radix Notoginseng, 20 parts of Rhizoma Fagopyri Dibotryiss.
Prescription of the present invention is rigorous, from multi-level, too many levels, the whole conditioning of many target spots, main pathogenesis for gastric ulcer, can also adjust disorderly digestive function, improve healing quality, reduce the relapse rate of gastric ulcer, particularly reduced proton pump inhibitor dependence effect, have no side effect, firmly got Building patient trust and welcome.The present invention is the main pathogenesis for knot, qi depression to blood stasis in weakness of the spleen and stomach, pyretic toxicity with spleen invigorating heat clearing and blood stasis dispersing, eliminate the damage factor of ulcer, with Rhizoma Curcumae, Rhizoma Sparganii, coordinate with Radix Codonopsis, Radix Glycyrrhizae, Poria, make that blood stasis dispelling of the present invention stimulates the menstrual flow, when removing blood stasis eliminating mass, circulation of qi promoting removing food stagnancy, avoid injuring taste; In Concha Ostreae (calcined), contain a large amount of calcium carbonate and calcium phosphate, make in the present invention under one's belt and gastric acid, play and restrain effect astringent or styptic treatment for spontaneous sweating, relieving gastric hyperacidity to alleviate stomachache.The present invention is through a large amount of clinical uses, and when using 3 months, 80% patient cures substantially, under scope gastric ulcer many places in the H1-S2 phase, further consultation after 6 months, only 13% Stomach in Patients ulcer recurrence.
The specific embodiment
Below, by specific embodiment, technical scheme of the present invention is elaborated, in embodiment 1-5, the present invention proposes a kind of raw material composition as shown in the table by weight that is used for the treatment of gastric ulcer and adjusts the drug regimen of digestive function.
The present invention is through a large amount of clinical uses, and when using 3 months, 80% patient cures substantially, under scope gastric ulcer many places in the H1-S2 phase, further consultation after 6 months, only 13% Stomach in Patients ulcer recurrence.
The above; it is only the preferably specific embodiment of the present invention; but protection scope of the present invention is not limited to this; anyly be familiar with those skilled in the art in the technical scope that the present invention discloses; according to technical scheme of the present invention and inventive concept thereof, be equal to replacement or changed, within all should being encompassed in protection scope of the present invention.
Claims (4)
1. be used for the treatment of gastric ulcer and adjust the drug regimen of digestive function, it is characterized in that, its raw material comprises by weight: Radix Codonopsis 19-21 part, Fructus Crataegi 4-6 part, Radix Glycyrrhizae 9-11 part, Poria 14-16 part, Herba Taraxaci 14-16 part, Rhizoma Coptidis 1-2 part, Concha Ostreae (calcined) 14-16 part, Caulis Perillae 7-9 part, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China 7-9 part, Radix Rehmanniae 2-4 part, Rhizoma Curcumae 7-9 part, Rhizoma Sparganii 9-11 part, Radix Notoginseng 9-11 part, Rhizoma Fagopyri Dibotryis 18-20 part.
2. be used for the treatment of as claimed in claim 1 gastric ulcer and adjust the drug regimen of digestive function, it is characterized in that Radix Codonopsis 19.3-20.7 part, Fructus Crataegi 4.2-5.7 part, Radix Glycyrrhizae 9.5-10.5 part, Poria 14.9-15.7 part, Herba Taraxaci 14.6-15.3 part, Rhizoma Coptidis 1.2-1.7 part, Concha Ostreae (calcined) 14.3-15.6 part, Caulis Perillae 7.8-8.3 part, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China 7.3-8.1 part, Radix Rehmanniae 2.2-3.6 part, Rhizoma Curcumae 7.5-8.5 part, Rhizoma Sparganii 9.6-10.2 part, Radix Notoginseng 9.2-10.8 part, Rhizoma Fagopyri Dibotryis 18.6-19.4 part.
3. be used for the treatment of as claimed in claim 1 or 2 gastric ulcer and adjust the drug regimen of digestive function, it is characterized in that, the weight ratio of Rhizoma Curcumae and Rhizoma Sparganii is 8:10.
4. be used for the treatment of as claimed in claim 3 gastric ulcer and adjust the drug regimen of digestive function, it is characterized in that 20 parts of Radix Codonopsis, 5 parts of Fructus Crataegis, 10 parts, Radix Glycyrrhizae, 15 parts, Poria, 15 parts of Herba Taraxacis, 1.5 parts of Rhizoma Coptidis, 15 parts of Concha Ostreae (calcined)s, 8 parts of Caulis Perillaes, 8 parts of CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China, 3 parts, the Radix Rehmanniae, 8 parts of Rhizoma Curcumae, 10 parts of Rhizoma Sparganii, 10 parts of Radix Notoginseng, 20 parts of Rhizoma Fagopyri Dibotryiss.
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Cited By (1)
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| CN104225436A (en) * | 2014-09-18 | 2014-12-24 | 高忠青 | Drug provided with sugar coating and having stomach easing and gastric ulcer treatment functions and production process of drug |
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