CN103230518A - Traditional Chinese medical composition for treating peptic ulcer - Google Patents

Traditional Chinese medical composition for treating peptic ulcer Download PDF

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Publication number
CN103230518A
CN103230518A CN2013101406893A CN201310140689A CN103230518A CN 103230518 A CN103230518 A CN 103230518A CN 2013101406893 A CN2013101406893 A CN 2013101406893A CN 201310140689 A CN201310140689 A CN 201310140689A CN 103230518 A CN103230518 A CN 103230518A
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chinese medicine
composition
peptic ulcer
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CN103230518B (en
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姜晓红
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Jiang Ling
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Abstract

The invention relates to a traditional Chinese medical composition for treating peptic ulcer. The composition comprises the traditional Chinese medicine raw materials by weight as follows: 25-30g of Codonopsis pilosula, 20-25g of Bletilla, 30-35g of oyster, 25-30g of cuttlebone, 20-25g of dandelion, 15-20g of immature bitter orange, 20-25g of Mangnolia officinalis, 15-20g of pericarpium citri reticulatae viride, 30-35g of radix paeoniae alba, 15-20g of corydalis tuber, 10-15g of pseudo-ginseng and 3-6g of liquorice. The components of the composition provided by the invention are prepared by natural traditional Chinese medicine raw materials, and the composition is simple to prepare, wide in medicine source and low in cost. The composition is remarkable in curative effect and free from toxic and side effects through clinical application verification. The total effective rate reaches 94.88%, and the cure rate reaches 88.5%.

Description

A kind of Chinese medicine composition for the treatment of peptic ulcer
Technical field:
The present invention relates to a kind of field of Chinese medicines, specifically a kind of Chinese medicine composition for the treatment of peptic ulcer.
Background technology:
Peptic ulcer mainly refers to gastric ulcer and duodenal ulcer, and pathological changes is confined to stomach and 12 and refers to mucosa.The trend that the peptic ulcer patient increases day by day is very remarkable, mainly due to diet can not control, sudden and violent wine gluttony or work unordered, fatigue and diet do not have rule or numerous factors such as long-term nutrition imbalance, nervous, medicine irritation due to.Now become a kind of commonly encountered diseases and frequently-occurring disease, brought great misery to the patient, caused patients ' life quality to descend.
Chinese medicine thinks that the pathogenetic reason of ulcer mainly comprises: weakness of the spleen and stomach, and drinking and eating irregularly, feelings will is hindered, pathogen infringement and drug induced injury etc.It is generally acknowledged that human digestive ulcer disease is many because gastric mucosa damage factor (hydrion, bile, medicine etc.) and defence factor (coat of the stomach mucus, closely connect between epithelial cell, the prostaglandin that gastric mucosal blood flow and epithelial cell produce etc.) interaction between, all factors that attack factor enhancing or mucosa defense function are weakened all may become aetiology of Peptic Ulcer; The growth and decline of both sides' strength cause generation or the healing of ulcer.Drug therapy to Peptic Ulcers is also closely related with this two aspect.
Treatment Chinese and western medicine to peptic ulcer all can obtain clinical efficacy at present, and especially Western medicine antacid, receptor antagonist, proton pump inhibitor, bismuth etc. continue to bring out, and the clinical cure rate of peptic ulcer obviously improves, but easily relapse rate is higher.Therefore anti-peptic ulcer recurrence treatment, the radical cure peptic ulcer becomes the research focus.
According to theory of Chinese medical science, at the pathogeny of peptic ulcer, carry out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention:
The present invention is in order to overcome the deficiencies in the prior art, provides that a kind of preparation is easy, the medicine source is wide, cost is low, good effect, the Chinese medicine composition of the treatment peptic ulcer that toxic and side effects is little.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine composition for the treatment of peptic ulcer is characterized in that being made up of following Chinese medicine raw materials by weight proportion: Radix Codonopsis 25-30 gram, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-25 gram, Concha Ostreae 30-35 gram, Endoconcha Sepiae 25-30 gram, Herba Taraxaci 20-25 gram, Fructus Aurantii Immaturus 15-20 gram, Cortex Magnoliae Officinalis 20-25 gram, Pericarpium Citri Reticulatae Viride 15-20 gram, Radix Paeoniae Alba 30-35 gram, Rhizoma Corydalis 15-20 gram, Radix Notoginseng 10-15 gram, Radix Glycyrrhizae 3-6 gram.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of peptic ulcer is characterized in that being made up of the raw material of Chinese medicine of following weight: Radix Codonopsis 25 grams, Pseudobulbus Bletillae (Rhizoma Bletillae) 20 grams, Concha Ostreae 30 grams, Endoconcha Sepiae 30 grams, Herba Taraxaci 20 grams, Fructus Aurantii Immaturus 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Citri Reticulatae Viride 20 grams, the Radix Paeoniae Alba 30 grams, Rhizoma Corydalis 15 grams, Radix Notoginseng 10 grams, Radix Glycyrrhizae 5 grams.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In the present invention in the drug composition: Radix Codonopsis has the effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting; The Pseudobulbus Bletillae (Rhizoma Bletillae) has tonifying the lung, hemostasis, and detumescence, granulation promoting is held back the effect of skin ulcer; The Concha Ostreae detoxifcation is eased pain, is had suppressing the hyperactive liver and subsiding YANG, tranquillizing the mind by relieving convulsion, and hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating effect; Endoconcha Sepiae has the effect that astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving gastric hyperacidity to alleviate stomachache, removing dampness are held back skin ulcer; Herba Taraxaci has the effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Fructus Aurantii Immaturus has the effect of the diffusing painful abdominal mass of reducing phlegm, dispelling the stagnated QI removing food stagnancy; Cortex Magnoliae Officinalis has circulation of qi promoting removing food stagnancy, dampness except effect full, lowering the adverse QI to relieve asthma; Pericarpium Citri Reticulatae Viride has soothing the liver dispelling the stagnated QI, the stagnant effect of removing food stagnancyization; The Radix Paeoniae Alba has the effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Rhizoma Corydalis is controlled depressed the stagnating of taste and is not loose, main asthenia cold diarrhea, and cardiac and abdominal pain, the therapeutic method to keep the adverse QI flowing downwards helps digestion; Radix Notoginseng has hemostasis, dissipating blood stasis, detumescence, the effect of pain relieving; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.Drug component in the present composition is through dialectical compatibility, complements each other using, and has synergism, thereby reaches the purpose for the treatment of peptic ulcer.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, the medicine source is wide, cost is low.Through the clinical practice checking, it is evident in efficacy, has no side effect, and total effective rate reaches 94.88%, cure rate rate 88.5%.
The specific embodiment
Embodiment 1: a kind of Chinese medicine composition for the treatment of peptic ulcer, it is made up of following Chinese medicine raw materials by weight proportion: Radix Codonopsis 25-30 gram, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-25 gram, Concha Ostreae 30-35 gram, Endoconcha Sepiae 25-30 gram, Herba Taraxaci 20-25 gram, Fructus Aurantii Immaturus 15-20 gram, Cortex Magnoliae Officinalis 20-25 gram, Pericarpium Citri Reticulatae Viride 15-20 gram, Radix Paeoniae Alba 30-35 gram, Rhizoma Corydalis 15-20 gram, Radix Notoginseng 10-15 gram, Radix Glycyrrhizae 3-6 gram.
Chinese medicine composition of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soaked 20~30 minutes, add water again and do not have about 8 centimetres of powder, decoct.Adopt intense fire to decoct earlier, the back of boiling takes concoction with slow fire boiling 20~30 minutes; Add water and carry out decocting the second time again, decoction took concoction in 15~20 minutes after water boiled.Twice decoction removed slag and merged behind the extracting juice.
Embodiment 2: a kind of Chinese medicine composition for the treatment of peptic ulcer, its raw material of Chinese medicine by following weight is formed: Radix Codonopsis 25 grams, Pseudobulbus Bletillae (Rhizoma Bletillae) 20 grams, Concha Ostreae 30 grams, Endoconcha Sepiae 30 grams, Herba Taraxaci 20 grams, Fructus Aurantii Immaturus 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Citri Reticulatae Viride 20 grams, the Radix Paeoniae Alba 30 grams, Rhizoma Corydalis 15 grams, Radix Notoginseng 10 grams, Radix Glycyrrhizae 5 grams.
Embodiment 3: a kind of Chinese medicine composition for the treatment of peptic ulcer is characterized in that being made up of following Chinese medicine raw materials by weight proportion: Radix Codonopsis 30 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 22 grams, Concha Ostreae 35 grams, Endoconcha Sepiae 25 grams, Herba Taraxaci 22 grams, Fructus Aurantii Immaturus 18 grams, Cortex Magnoliae Officinalis 25 grams, Pericarpium Citri Reticulatae Viride 18 grams, the Radix Paeoniae Alba 35 grams, Rhizoma Corydalis 18 grams, Radix Notoginseng 12 grams, Radix Glycyrrhizae 3 grams.
Embodiment 4: a kind of Chinese medicine composition for the treatment of peptic ulcer is characterized in that being made up of following Chinese medicine raw materials by weight proportion: Radix Codonopsis 28 grams, Pseudobulbus Bletillae (Rhizoma Bletillae) 25 grams, Concha Ostreae 32 grams, Endoconcha Sepiae 28 grams, Herba Taraxaci 25 grams, Fructus Aurantii Immaturus 15 grams, Cortex Magnoliae Officinalis 22 grams, Pericarpium Citri Reticulatae Viride 15 grams, the Radix Paeoniae Alba 32 grams, Rhizoma Corydalis 20 grams, Radix Notoginseng 15 grams, Radix Glycyrrhizae 6 grams.
A kind of Chinese medicine composition for the treatment of peptic ulcer, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is used for many years clinically, clinical observation case 78 examples, and male 43 examples, women 35 examples, at 30~55 years old age, the course of disease all reaches 1-4.
Two, usage and dosage: during clinical practice, the component in the compositions, consumption are taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.Potion on the one, the about 300ml of twice extracting juice of decocting takes sooner or later 30 minutes ante cibum.Ten days is a course for the treatment of.
Three, criterion of therapeutical effect:
? Curative effect Symptom The sign electronic gastroscopy
Recovery from illness Complete obiteration Negative Ulcer S1 phase or S2 phase
Effectively Obviously alleviate Positive or negative Ulcer H1 phase or H2 phase
Invalid Do not disappear Positive Ulcer A1 phase or A2 phase
Four, therapeutic effect: in the clinical observation case, take medicine 1-2 the course for the treatment of 69 examples of fully recovering, produce effects 3 examples, effective 2 examples, invalid 4 examples.Do not see this medicine toxic side effect in the treatment clinical course, also do not see cause perforation, metabolic alkalosis and sodium retention, constipation, intestinal obstruction, anaphylaxis, feel sick, untoward reaction such as diarrhoea, stomachache, paraesthesia, headache take place, and do not have recurrence after curing drug withdrawal.
Five, model case:
1, Lee, the man, 42 years old, in November, 2008 hospital's barium meal examination was diagnosed as duodenal bulbar ulcer; Tcm diagnosis is the weakness of the spleen and stomach gastrorrhagia, and Western medicine diagnose is duodenal ulcer, namely cures a course for the treatment of with pharmaceutical composition of the present invention, so far not recurrence.
2, Zhang, the woman, 46 years old, in August, 2009 hospital's barium meal examination was diagnosed as gastric ulcer, and tcm diagnosis is gastric abscess, and Western medicine diagnose is ulcer of upper digestive tract, cures a course for the treatment of with pharmaceutical composition of the present invention, so far not recurrence.
3, permitted certain, the man, 55 years old, in October, 2009, hospital gastroscope checked, was diagnosed as duodenal ulcer and erosive gastritis, and tcm diagnosis is gastric abscess, and Western medicine diagnose is ulcer of upper digestive tract, cures three courses for the treatment of with pharmaceutical composition of the present invention, so far not recurrence.

Claims (2)

1. a Chinese medicine composition for the treatment of peptic ulcer is characterized in that being made up of following Chinese medicine raw materials by weight proportion: Radix Codonopsis 25-30 gram, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-25 gram, Concha Ostreae 30-35 gram, Endoconcha Sepiae 25-30 gram, Herba Taraxaci 20-25 gram, Fructus Aurantii Immaturus 15-20 gram, Cortex Magnoliae Officinalis 20-25 gram, Pericarpium Citri Reticulatae Viride 15-20 gram, Radix Paeoniae Alba 30-35 gram, Rhizoma Corydalis 15-20 gram, Radix Notoginseng 10-15 gram, Radix Glycyrrhizae 3-6 gram.
2. the Chinese medicine composition for the treatment of peptic ulcer according to claim 1 is characterized in that being made up of the raw material of Chinese medicine of following weight: Radix Codonopsis 25 grams, Pseudobulbus Bletillae (Rhizoma Bletillae) 20 grams, Concha Ostreae 30 grams, Endoconcha Sepiae 30 grams, Herba Taraxaci 20 grams, Fructus Aurantii Immaturus 20 grams, Cortex Magnoliae Officinalis 20 grams, Pericarpium Citri Reticulatae Viride 20 grams, the Radix Paeoniae Alba 30 grams, Rhizoma Corydalis 15 grams, Radix Notoginseng 10 grams, Radix Glycyrrhizae 5 grams.
CN201310140689.3A 2013-04-04 2013-04-04 Traditional Chinese medical composition for treating peptic ulcer Expired - Fee Related CN103230518B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104013921A (en) * 2014-06-27 2014-09-03 田丽华 Medicament composition for treating gastric ulcer and adjusting digestive functions
CN106421051A (en) * 2016-11-29 2017-02-22 佘延英 Traditional Chinese medicine for treating peptic ulcer

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1100651A (en) * 1994-03-15 1995-03-29 广东医学院医药科技开发中心 Chinese herbal prepn. for curing chronic gastroenteritis and peptic gastric ulcer
CN1682878A (en) * 2005-01-25 2005-10-19 蒋迎春 Medicine for treating digestive tract ulcer and stomach cercinoma prophase pathologic change
CN101066445A (en) * 2007-06-29 2007-11-07 曹国胜 Chinese medicine prepn for curing gastropathy radically
CN102188614A (en) * 2009-05-27 2011-09-21 成仕孝 Capsule for gastric ulcer
CN102824587A (en) * 2011-07-07 2012-12-19 随洪涛 Traditional Chinese medicinal formula for treating gastropathy

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1100651A (en) * 1994-03-15 1995-03-29 广东医学院医药科技开发中心 Chinese herbal prepn. for curing chronic gastroenteritis and peptic gastric ulcer
CN1682878A (en) * 2005-01-25 2005-10-19 蒋迎春 Medicine for treating digestive tract ulcer and stomach cercinoma prophase pathologic change
CN101066445A (en) * 2007-06-29 2007-11-07 曹国胜 Chinese medicine prepn for curing gastropathy radically
CN102188614A (en) * 2009-05-27 2011-09-21 成仕孝 Capsule for gastric ulcer
CN102824587A (en) * 2011-07-07 2012-12-19 随洪涛 Traditional Chinese medicinal formula for treating gastropathy

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104013921A (en) * 2014-06-27 2014-09-03 田丽华 Medicament composition for treating gastric ulcer and adjusting digestive functions
CN106421051A (en) * 2016-11-29 2017-02-22 佘延英 Traditional Chinese medicine for treating peptic ulcer

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