CN106008459B - 一种曲格列汀的制备方法 - Google Patents
一种曲格列汀的制备方法 Download PDFInfo
- Publication number
- CN106008459B CN106008459B CN201610642548.5A CN201610642548A CN106008459B CN 106008459 B CN106008459 B CN 106008459B CN 201610642548 A CN201610642548 A CN 201610642548A CN 106008459 B CN106008459 B CN 106008459B
- Authority
- CN
- China
- Prior art keywords
- formula
- compound shown
- lieting
- preparation
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (8)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610642548.5A CN106008459B (zh) | 2016-08-05 | 2016-08-05 | 一种曲格列汀的制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610642548.5A CN106008459B (zh) | 2016-08-05 | 2016-08-05 | 一种曲格列汀的制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN106008459A CN106008459A (zh) | 2016-10-12 |
CN106008459B true CN106008459B (zh) | 2018-07-13 |
Family
ID=57134649
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610642548.5A Active CN106008459B (zh) | 2016-08-05 | 2016-08-05 | 一种曲格列汀的制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106008459B (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106749176A (zh) * | 2016-12-08 | 2017-05-31 | 郑州明泽医药科技有限公司 | 一种曲格列汀琥珀酸盐的纯化方法 |
CN107573388A (zh) * | 2017-08-30 | 2018-01-12 | 中国石油大学(华东) | 叠氮化脱氧核苷的制备方法及采用叠氮化脱氧核苷制备氨基修饰脱氧核苷的方法 |
CN112480075A (zh) * | 2020-12-22 | 2021-03-12 | 山东永丞制药有限公司 | 一种琥珀酸曲格列汀的精制方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104961726A (zh) * | 2015-06-19 | 2015-10-07 | 浙江永宁药业股份有限公司 | 一种曲格列汀的制备方法 |
CN105418580A (zh) * | 2014-09-11 | 2016-03-23 | 上海医药工业研究院 | 制备曲格列汀的新工艺 |
CN105524042A (zh) * | 2014-10-22 | 2016-04-27 | 重庆医药工业研究院有限责任公司 | 一种制备曲格列汀的方法 |
-
2016
- 2016-08-05 CN CN201610642548.5A patent/CN106008459B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105418580A (zh) * | 2014-09-11 | 2016-03-23 | 上海医药工业研究院 | 制备曲格列汀的新工艺 |
CN105524042A (zh) * | 2014-10-22 | 2016-04-27 | 重庆医药工业研究院有限责任公司 | 一种制备曲格列汀的方法 |
CN104961726A (zh) * | 2015-06-19 | 2015-10-07 | 浙江永宁药业股份有限公司 | 一种曲格列汀的制备方法 |
Also Published As
Publication number | Publication date |
---|---|
CN106008459A (zh) | 2016-10-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN111333633A (zh) | 一种瑞卢戈利的中间体化合物及其制备方法和用途 | |
CN106008459B (zh) | 一种曲格列汀的制备方法 | |
CN105541844B (zh) | 一种高纯度利拉利汀的简易制备方法 | |
CN109438405A (zh) | 一种3-(苄氧基)-4-氧代-4h-吡喃-2-羧酸的合成方法 | |
US20070207246A1 (en) | Method of Sucralose Synthesis Yield | |
JP6811717B2 (ja) | トピロキソスタット及びその中間体の調製のための方法 | |
CN112441942B (zh) | 沙坦类中间体多溴取代物的脱溴方法 | |
EP2608791B1 (en) | A process for the preparation of imatinib base | |
CN103588765B (zh) | 阿齐沙坦酯或其盐的合成方法及其中间体和中间体的合成方法 | |
CN101376667B (zh) | 一种合成齐多夫定的中间体及其制备方法和该中间体在合成齐多夫定中的应用 | |
JP3440129B2 (ja) | グルタミン誘導体の製造法 | |
CN104803908A (zh) | 2-异丙氧基-5-甲基-4-(4-哌啶基)苯胺二盐酸盐的水合物、其制备方法及用途 | |
KR20100045985A (ko) | 톨루이딘 화합물의 제조 방법 | |
CN103159620A (zh) | 一种2-羟基间苯二甲酸的制备方法 | |
CN103087090B (zh) | 一种二棕榈酰基磷脂酰乙醇胺的合成方法 | |
CN102746207A (zh) | 一种奥拉西坦的合成方法 | |
CN100491377C (zh) | 鸟嘌呤的一锅法合成方法 | |
KR20120026024A (ko) | N-알콕시카르보닐-tert-류신의 제조법 | |
TWI617562B (zh) | 用於由4-胺基-2,5-二甲氧基嘧啶製備2-胺基-5,8-二甲氧基[1,2,4]三唑并[1,5-c]嘧啶的改良方法 | |
CN101857575A (zh) | 2-氨基-5-甲基吡嗪的工业化制备方法 | |
JP2012020970A (ja) | {2−アミノ−1,4−ジヒドロ−6−メチル−4−(3−ニトロフェニル)−3,5−ピリジンジカルボン酸3−(1−ジフェニルメチルアゼチジン−3−イル)エステル5−イソプロピルエステル}の製造方法 | |
CN106083822B (zh) | 一种甲磺酸达比加群酯中间体的制备方法 | |
CN104672239A (zh) | 一种采用一锅法制备阿巴卡韦式v中间体的工艺 | |
JP3511788B2 (ja) | 7−アミノ−2,3−ジヒドロ−2−オキソ−ピリド [2,3−d] ピリミジン及びその製造法 | |
WO2009017239A2 (en) | Process for producing toluidine compound |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB02 | Change of applicant information |
Address after: 253100 Eastern District of Plain Economic Development Zone, Shandong, Dezhou Applicant after: Shandong Fourth Ring pharmaceutical Limited by Share Ltd Address before: South West East Economic Development Zone 253100 Shandong city of Dezhou Province plain county first Applicant before: Pingyuan Pharmaceutical Co Ltd |
|
CB02 | Change of applicant information | ||
CB03 | Change of inventor or designer information |
Inventor after: Li Gang Inventor after: Sun Chongguo Inventor after: Guo Jianjun Inventor after: Liu Huimin Inventor after: Xu Chunhai Inventor before: Li Gang Inventor before: Sun Chongguo Inventor before: Guo Jianjun Inventor before: Liu Huimin |
|
CB03 | Change of inventor or designer information | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A preparation method of trogliptin Effective date of registration: 20211214 Granted publication date: 20180713 Pledgee: Bank of Qilu Co.,Ltd. Dezhou Pingyuan sub branch Pledgor: SHANDONG SIHUAN PHARMACEUTICAL CO.,LTD. Registration number: Y2021980014872 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |