CN105902422A - Acne removal essence and preparation method thereof - Google Patents

Acne removal essence and preparation method thereof Download PDF

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Publication number
CN105902422A
CN105902422A CN201610230096.XA CN201610230096A CN105902422A CN 105902422 A CN105902422 A CN 105902422A CN 201610230096 A CN201610230096 A CN 201610230096A CN 105902422 A CN105902422 A CN 105902422A
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extract
essence
root extract
radix
acne
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CN201610230096.XA
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孔红飞
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Hangzhou Chengfei Cosmetics Co Ltd
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Hangzhou Chengfei Cosmetics Co Ltd
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Priority to CN201610230096.XA priority Critical patent/CN105902422A/en
Publication of CN105902422A publication Critical patent/CN105902422A/en
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Abstract

Belonging to the technical field of cosmetics, the invention relates to an acne removal essence and a preparation method thereof. The acne removal essence comprises glycerin, butylene glycol, hydroxyethylurea, a cinnamon bark extract, a ginger root extract, a Sanguisorba officinalis root extract, beta-glucan, quaternium-73, a Bacillus/soybean fermented product extract, folic acid, sodium hyaluronate, 1, 2-hexanediol, xanthan gum, a alkanet extract, a tremella fruit body extract, olive oil, PEG-7 esters, essence, a solubilizer, a preservative, and deionized water. The essence provided by the invention can reduce skin acne fundamentally, finally performs sterilization and eliminates existing acnes, thereby completely solving the acne problem and completely eradicating the acne recurrence problem.

Description

A kind of anti-acne essence and preparation method thereof
Technical field
The present invention relates to a kind of anti-acne essence and preparation method thereof, belong to cosmetic technical field.
Background technology
Acne is that a kind of chronic inflammatory skin of pilosebaceous unit is sick, calls comedo, acne, is mainly apt to occur in Teenager is the biggest to teen-age psychology and social influence.But, due to environmental pollution, urban life operating pressure increase etc. Reason, the most increasing adult has the puzzlement of acne, life, work, psychology confidence and the social communication etc. to them Create impact in various degree.
The generation of acne is main with hypersteatosis, pilosebaceous duct blocking, antibacterial infection and inflammatory reaction etc. Factor is closely related.The level of androgen particularly testosterone in descendant's body that adolesces raises rapidly, promotes that sebaceous gland is grown And produce a large amount of sebum.The dyskeratosis of pilosebaceous duct causes catheter blockage, dyssebacia simultaneously, forms cutin The i.e. micropowder of bolt stings.Multiple-microorganism especially propionibacterium acnes amount reproduction in hair follicle, the lipase that propionibacterium acnes produces Decomposing sebum and generate free fatty, chemotactic inflammatory cell and medium, finally induce and increase the weight of inflammatory reaction simultaneously.But due to Cause and the trigger mechanism of acne are the most complicated, and this makes acne be difficult to treatment.
In prior art, product on the market mainly solves skin acne problem by the method for sterilization, belongs to Cure the symptoms, not the disease so that acne recurs over and over, bring puzzlement greatly to consumer.
Summary of the invention
It is an object of the invention to overcome above-mentioned deficiency present in prior art, and provide one can thoroughly solve Cuo Anti-acne essence of skin ulcer problem and preparation method thereof.
The present invention solves the problems referred to above and be the technical scheme is that a kind of anti-acne essence, it is characterised in that described essence China liquid include glycerol, butanediol, ethoxy urea, cinnamon bark extract, ginger-root extract, Radix Sanguisorbae root extract, beta glucan, Quaternary ammonium salt-73, bacillus cereus/fermented soybean product extract, folic acid, hyaluronate sodium, 1,2-hexanediol, xanthan gum, Radix Arnebiae (Radix Lithospermi) Root extract, Tremella fructification extract, olive oil PEG-7 esters, essence, solubilizing agent, preservative and deionized water.
Further, according to the gross mass percentages of essence, the content of each component is: glycerol 3%~6%, butanediol 3%~6%, ethoxy urea 3%~5%, cinnamon bark extract, ginger-root extract and Radix Sanguisorbae root extract each 1%~4%, β-Portugal gathers Sugar 3%~7%, quaternary ammonium salt-73 is 0.0001%~0.0005%, bacillus cereus/fermented soybean product extract, folic acid, hyalomitome Acid sodium and 1,2-hexanediol each 0.1%~2%, xanthan gum 0.1%~0.2%, Radix Arnebiae (Radix Lithospermi) extract 0.01%~0.5%, Tremella is real Body extract 0.0001%~0.0005%, olive oil PEG-7 esters 0.1%~3%, essence 0.01%~0.1%, solubilizing agent 0.1%~ 0.3%, preservative 0.1%~0.3%, surplus is deionized water.
The product produced according to this formula, has removing acnes and controlling oil and effect of effective acne removing print, by edible perfume (or spice) Material: Cortex Cinnamomi, Rhizoma Zingiberis Recens, Radix Sanguisorbae plant component suppress the fat secretion of sebum excess effectively, reduces sebum enzymatic activity, reduces free The generation of fatty acid, fundamentally reduces the nutrition needed for bacterial growth, final pasteurising, eliminates existing acne and pox print, makes pox Pox skin fast quick-recovery natural health state.
Further, according to the gross mass percentages of essence, the content of each component is: glycerol 3%~6%, butanediol 3%~6%, ethoxy urea 3%~5%, cinnamon bark extract, ginger-root extract and Radix Sanguisorbae root extract each 3%~4%, β-Portugal gathers Sugar 5%~7%, quaternary ammonium salt-73 is 0.0001%~0.0005%, bacillus cereus/fermented soybean product extract, folic acid, hyalomitome Acid sodium and 1,2-hexanediol each 0.1%~1.5%, xanthan gum 0.1%~0.2%, Radix Arnebiae (Radix Lithospermi) extract 0.01%~0.1%, Tremella Entity extraction thing 0.0001%~0.0005%, olive oil PEG-7 esters 0.1%~3%, essence 0.01%~0.1%, solubilizing agent 0.1% ~0.3%, preservative 0.1%~0.3%, surplus is deionized water.
The product produced according to this formula, has effect of removing acnes and controlling oil emphatically, can effectively control skin excess Fat secretion, fundamentally reduces, the nutrition needed for bacterial growth.Make small pox skin fast quick-recovery natural health state.
Further, according to the gross mass percentages of essence, the content of each component is: glycerol 3%~6%, butanediol 3%~6%, ethoxy urea 3%~5%, cinnamon bark extract, ginger-root extract and Radix Sanguisorbae root extract each 1%~3%, β-Portugal gathers Sugar 3%~5%, quaternary ammonium salt-73 is 0.0001%~0.0005%, bacillus cereus/fermented soybean product extract, folic acid, hyalomitome Acid sodium and 1,2-hexanediol each 0.5%~2%, xanthan gum 0.1%~0.2%, Radix Arnebiae (Radix Lithospermi) extract 0.01%~0.5%, Tremella is real Body extract 0.0001%~0.0005%, olive oil PEG-7 esters 0.1%~3%, essence 0.01%~0.1%, solubilizing agent 0.1%~ 0.3%, preservative 0.1%~0.3%, surplus is deionized water.
The product produced according to this formula, has effect of oil control and acne removal print emphatically, can effectively control skin oil-water Balance, slows down scytitis, makes skin recover the natural health state that smooth children is tender.
A kind of method preparing above-mentioned anti-acne essence, comprises the following steps:
(1) mixture A is obtained after quaternary ammonium salt-73, butanediol being heated to 60 DEG C of dissolvings completely;
(2) the mixture A that step (1) is obtained and deionized water, glycerol, xanthan gum, Tremella fructification extract stirring and dissolving Mixture B is obtained after Wan Quan;
(3) mixture B step (2) obtained extracts with ethoxy urea, cinnamon bark extract, ginger-root extract, Radix Sanguisorbae root Thing, beta glucan, bacillus cereus/fermented soybean product extract, folic acid, hyaluronate sodium, 1,2-hexanediol, olive oil PEG- Mixture C is obtained after 7 esters and olive oil PEG-7 esters mixing and stirring;
(4) mixture C that step (3) is obtained with has dissolved essence, solubilizing agent, preservative mixing and stirring Product.
Further, in above-mentioned preparation method, according to the gross mass percentages of essence, the content of each component is: Glycerol 3%~6%, butanediol 3%~6%, ethoxy urea 3%~5%, cinnamon bark extract, ginger-root extract and Radix Sanguisorbae root extract Thing each 1%~4%, beta glucan 3%~7%, quaternary ammonium salt-73 is 0.0001%~0.0005%, and bacillus cereus/fermented soybean product carries Take thing, folic acid, hyaluronate sodium and 1,2-hexanediol each 0.1%~2%, xanthan gum 0.1%~0.2%, Radix Arnebiae (Radix Lithospermi) extract 0.01% ~0.5%, Tremella fructification extract 0.0001%~0.0005%, olive oil PEG-7 esters 0.1%~3%, essence 0.01%~ 0.1%, solubilizing agent 0.1%~0.3%, preservative 0.1%~0.3%, surplus is deionized water.
Further, in above-mentioned preparation method, according to the gross mass percentages of essence, the content of each component is: Glycerol 3%~6%, butanediol 3%~6%, ethoxy urea 3%~5%, cinnamon bark extract, ginger-root extract and Radix Sanguisorbae root extract Thing each 3%~4%, beta glucan 5%~7%, quaternary ammonium salt-73 is 0.0001%~0.0005%, and bacillus cereus/fermented soybean product carries Take thing, folic acid, hyaluronate sodium and 1,2-hexanediol each 0.1%~1.5%, xanthan gum 0.1%~0.2%, Radix Arnebiae (Radix Lithospermi) extract 0.01%~0.1%, Tremella fructification extract 0.0001%~0.0005%, olive oil PEG-7 esters 0.1%~3%, essence 0.01%~0.1%, solubilizing agent 0.1%~0.3%, preservative 0.1%~0.3%, surplus is deionized water.
Further, in above-mentioned preparation method, according to the gross mass percentages of essence, the content of each component is: Glycerol 3%~6%, butanediol 3%~6%, ethoxy urea 3%~5%, cinnamon bark extract, ginger-root extract and Radix Sanguisorbae root extract Thing each 1%~3%, beta glucan 3%~5%, quaternary ammonium salt-73 is 0.0001%~0.0005%, and bacillus cereus/fermented soybean product carries Take thing, folic acid, hyaluronate sodium and 1,2-hexanediol each 0.5%~2%, xanthan gum 0.1%~0.2%, Radix Arnebiae (Radix Lithospermi) extract 0.01% ~0.5%, Tremella fructification extract 0.0001%~0.0005%, olive oil PEG-7 esters 0.1%~3%, essence 0.01%~ 0.1%, solubilizing agent 0.1%~0.3%, preservative 0.1%~0.3%, surplus is deionized water.
The present invention compared with prior art, has the following advantages and effect: the present invention have removing acnes and controlling oil and acne removing print Effect.Pass through flavorant: Cortex Cinnamomi, Rhizoma Zingiberis Recens, Radix Sanguisorbae plant component suppress the fat secretion of sebum excess effectively, reduce sebum Enzymatic activity, reduces the generation of free fatty, fundamentally reduces the nutrition needed for bacterial growth, final pasteurising, eliminate existing Acne, makes small pox skin fast quick-recovery natural health state, thus thoroughly solves acne problems, stop acne problem repeatedly;Energy The enough expansion effectively suppressing sebum hole, reduces pore dia.
Detailed description of the invention
Below by embodiment, the present invention is described in further detail, following example be explanation of the invention and The invention is not limited in following example.
The present embodiment includes glycerol, butanediol, ethoxy urea, Cortex Cinnamomi (CINNAMOMUMCASSIA) bark extract, Rhizoma Zingiberis Recens (ZINGIBEROFFICINALE) root extract, Radix Sanguisorbae (POTERIUMSANGUISORBA) root extract, beta glucan, quaternary ammonium Salt-73, bacillus cereus/fermented soybean product extract, folic acid, hyaluronate sodium, 1,2-hexanediol, xanthan gum, Radix Arnebiae (Radix Lithospermi) (LITHOSPERMUMERYTHRORHIZON) root extract, Tremella (TREMELLAFUCIFORMIS) fruiting body extract, Fructus Canarii albi Oil PEG-7 esters, essence, solubilizing agent, preservative and deionized water.
Wherein the function of fractions is as follows:
Glycerol: have moisturizing, humectation, high activity, antioxidation, rush refine effect.
Butanediol: moisturizing, antibacterial.
Ethoxy urea: in permeable entrance horny layer, increase moisture content of skin, alleviate and be dried, fill up microgroove, increase skin Elastic.
Cortex Cinnamomi (CINNAMOMUMCASSIA) bark extract: immune function of human body is had obvious potentiation.It is made It is that it can strengthen T lymphocytes in human body and the propagation of bone-marrow-derived lymphocyte and differentiation, and strengthens its function by mechanism;Strengthen and kill carefully The killing ability of born of the same parents and the phagocytic function of mononuclear phagocyte.
Rhizoma Zingiberis Recens (ZINGIBEROFFICINALE) root extract: anti-inflammatory.
Radix Sanguisorbae (POTERIUMSANGUISORBA) root extract: raise peripheral blood leucocyte, neutrophilic granulocyte, platelet, Improve Microcirculation in Bone Marrow.Regulate and improve body's immunity.
Beta glucan: moisture-keeping efficacy, beta glucan has film property, it is possible to helps skin to keep moisture, has stealthy skin The laudatory title of skin;Antioxidation, substantially reduces wrinkle of skin, improves skin elasticity;Protecting the skin from the injury of ultraviolet, skin supports The tolerance of imperial environmental stimuli;The use skinfeel that product is good can be given, increase the Transdermal absorption of activity.
Quaternary ammonium salt-73: sterilization.
Bacillus cereus/fermented soybean product extract: improve blood flow.
Folic acid: manufacture erythrocyte and leukocyte, strengthens immunocompetence.
Hyaluronate sodium: protection skin effect, can keep skin moisturizing smooth, fine and smooth tender, and high resilience has anti- Wrinkle, crease-resistant, aesthetic health care and the effect of recovery skin physiology function.
1,2-hexanediol: moisturizing, moisten.
Xanthan gum: promote skin absorption moisture.
Radix Arnebiae (Radix Lithospermi) (LITHOSPERMUMERYTHRORHIZON) root extract: anticancer, antiinflammatory, the effect such as antibacterial.
Tremella (TREMELLAFUCIFORMIS) fruiting body extract: there is raising immunity, antitumor, defying age, fall The function such as blood glucose and blood fat reducing.
Olive oil PEG-7 esters: have and help emulsifying, auxiliary solubilising and the effect of moisturizing, effectively reduce surface activity The zest of agent system, fabulous tax lipid improvement is dried tight skinfeel after washing.
The preparation method of the present embodiment, comprises the following steps:
(1) quaternary ammonium salt-73, butanediol are heated to 60 DEG C and dissolve completely, obtain mixture A.
(2) mixture A step (1) obtained and deionized water, glycerol, xanthan gum, Tremella (TREMELLAFUCIFORMIS) fruiting body extract stirring and dissolving is complete, obtains mixture B.
(3) the mixture B that step (2) is obtained and ethoxy urea, Cortex Cinnamomi (CINNAMOMUMCASSIA) bark extract, Rhizoma Zingiberis Recens (ZINGIBEROFFICINALE) root extract, Radix Sanguisorbae (POTERIUMSANGUISORBA) root extract, beta glucan, bud Spore bacillus/fermented soybean product extract, folic acid, hyaluronate sodium, 1,2-hexanediol, olive oil PEG-7 esters and olive oil PEG-7 esters mixing and stirring, obtains mixture C.
(4) mixture C that step (3) is obtained and the essence dissolved, solubilizing agent, preservative mixing and stirring Obtain final product.
Every composition presses the gross mass percentages of essence, such as following table:
Essence embodiment one, embodiment two and embodiment three obtained, takes and is respectively applied in right amount test as follows:
Test one:
(1) method of testing: the gel containing 5% essence is used for patients with acne by affected part position.
(2) test result: after 15 minutes, the situation such as following table of each treatment project:
Test two:
(1) test object: 38 patients having acne problems.
(2) method of testing: the essence obtained in Example two, uses the facial milk cleanser containing 0.001% essence, often They 3 times;Use the facial film containing 0.005% essence, 2 times a week.
(3) test result: fortnight erythra number may be reduced by 50%.
Test three:
(1) test object: 30 patients having acne problems, is divided into three groups, compiles as A, B, C group.
(2) method of testing: use object: the essence that embodiment one, embodiment two, embodiment three obtain respectively give A, B, The patient that C is tri-groups uses;
Using method: use the facial milk cleanser containing 0.001% essence, three times a day;Use the facial film containing 0.005% essence, 2 times a week.
(3) test result: after fortnight, the situation such as following table of each treatment project:
Although the present invention is open the most as above with embodiment, but it is not limited to protection scope of the present invention, and any be familiar with should The technical staff of item technology, in the change made without departing from the spirit and scope of the invention and retouching, all should belong to the present invention Protection domain.

Claims (8)

1. an anti-acne essence, it is characterised in that described essence includes that glycerol, butanediol, ethoxy urea, cinnamon bark carry Take thing, ginger-root extract, Radix Sanguisorbae root extract, beta glucan, quaternary ammonium salt-73, bacillus cereus/fermented soybean product extract, Folic acid, hyaluronate sodium, 1,2-hexanediol, xanthan gum, Radix Arnebiae (Radix Lithospermi) extract, Tremella fructification extract, olive oil PEG-7 ester Class, essence, solubilizing agent, preservative and deionized water.
Anti-acne essence the most according to claim 1, it is characterised in that: according to the gross mass percentages of essence, respectively The content of component is: glycerol 3%~6%, butanediol 3%~6%, ethoxy urea 3%~5%, cinnamon bark extract, ginger-root extract Each with Radix Sanguisorbae root extract 1%~4%, beta glucan 3%~7%, quaternary ammonium salt-73 is 0.0001%~0.0005%, bacillus cereus/big Bean tunning extract, folic acid, hyaluronate sodium and 1,2-hexanediol each 0.1%~2%, xanthan gum 0.1%~0.2%, Radix Arnebiae (Radix Lithospermi) Root extract 0.01%~0.5%, Tremella fructification extract 0.0001%~0.0005%, olive oil PEG-7 esters 0.1%~3%, Essence 0.01%~0.1%, solubilizing agent 0.1%~0.3%, preservative 0.1%~0.3%, surplus is deionized water.
Anti-acne essence the most according to claim 2, it is characterised in that: according to the gross mass percentages of essence, respectively The content of component is: glycerol 3%~6%, butanediol 3%~6%, ethoxy urea 3%~5%, cinnamon bark extract, ginger-root extract Each with Radix Sanguisorbae root extract 3%~4%, beta glucan 5%~7%, quaternary ammonium salt-73 is 0.0001%~0.0005%, bacillus cereus/big Bean tunning extract, folic acid, hyaluronate sodium and 1,2-hexanediol each 0.1%~1.5%, xanthan gum 0.1%~0.2% is purple Grass roots extract 0.01%~0.1%, Tremella fructification extract 0.0001%~0.0005%, olive oil PEG-7 esters 0.1%~ 3%, essence 0.01%~0.1%, solubilizing agent 0.1%~0.3%, preservative 0.1%~0.3%, surplus is deionized water.
Anti-acne essence the most according to claim 2, it is characterised in that: according to the gross mass percentages of essence, respectively The content of component is: glycerol 3%~6%, butanediol 3%~6%, ethoxy urea 3%~5%, cinnamon bark extract, ginger-root extract Each with Radix Sanguisorbae root extract 1%~3%, beta glucan 3%~5%, quaternary ammonium salt-73 is 0.0001%~0.0005%, bacillus cereus/big Bean tunning extract, folic acid, hyaluronate sodium and 1,2-hexanediol each 0.5%~2%, xanthan gum 0.1%~0.2%, Radix Arnebiae (Radix Lithospermi) Root extract 0.01%~0.5%, Tremella fructification extract 0.0001%~0.0005%, olive oil PEG-7 esters 0.1%~3%, Essence 0.01%~0.1%, solubilizing agent 0.1%~0.3%, preservative 0.1%~0.3%, surplus is deionized water.
5. the preparation method of an anti-acne essence as claimed in claim 1, it is characterised in that: described preparation method includes following Step:
(1) mixture A is obtained after quaternary ammonium salt-73, butanediol being heated to 60 DEG C of dissolvings completely;
(2) the mixture A that step (1) is obtained and deionized water, glycerol, xanthan gum, Tremella fructification extract stirring and dissolving Mixture B is obtained after Wan Quan;
(3) mixture B step (2) obtained extracts with ethoxy urea, cinnamon bark extract, ginger-root extract, Radix Sanguisorbae root Thing, beta glucan, bacillus cereus/fermented soybean product extract, folic acid, hyaluronate sodium, 1,2-hexanediol, olive oil PEG- Mixture C is obtained after 7 esters and olive oil PEG-7 esters mixing and stirring;
(4) mixture C that step (3) is obtained with has dissolved essence, solubilizing agent, preservative mixing and stirring Product.
Preparation method the most according to claim 5, it is characterised in that: according to the gross mass percentages of essence, each group Point content be: glycerol 3%~6%, butanediol 3%~6%, ethoxy urea 3%~5%, cinnamon bark extract, ginger-root extract and Radix Sanguisorbae root extract each 1%~4%, beta glucan 3%~7%, quaternary ammonium salt-73 is 0.0001%~0.0005%, bacillus cereus/Semen sojae atricolor Tunning extract, folic acid, hyaluronate sodium and 1,2-hexanediol each 0.1%~2%, xanthan gum 0.1%~0.2%, Radix Arnebiae (Radix Lithospermi) Extract 0.01%~0.5%, Tremella fructification extract 0.0001%~0.0005%, olive oil PEG-7 esters 0.1%~3% is fragrant Essence 0.01%~0.1%, solubilizing agent 0.1%~0.3%, preservative 0.1%~0.3%, surplus is deionized water.
Preparation method the most according to claim 5, it is characterised in that: according to the gross mass percentages of essence, each group Point content be: glycerol 3%~6%, butanediol 3%~6%, ethoxy urea 3%~5%, cinnamon bark extract, ginger-root extract and Radix Sanguisorbae root extract each 3%~4%, beta glucan 5%~7%, quaternary ammonium salt-73 is 0.0001%~0.0005%, bacillus cereus/Semen sojae atricolor Tunning extract, folic acid, hyaluronate sodium and 1,2-hexanediol each 0.1%~1.5%, xanthan gum 0.1%~0.2%, Radix Arnebiae (Radix Lithospermi) Root extract 0.01%~0.1%, Tremella fructification extract 0.0001%~0.0005%, olive oil PEG-7 esters 0.1%~3%, Essence 0.01%~0.1%, solubilizing agent 0.1%~0.3%, preservative 0.1%~0.3%, surplus is deionized water.
Preparation method the most according to claim 5, it is characterised in that: according to the gross mass percentages of essence, each group Point content be: glycerol 3%~6%, butanediol 3%~6%, ethoxy urea 3%~5%, cinnamon bark extract, ginger-root extract and Radix Sanguisorbae root extract each 1%~3%, beta glucan 3%~5%, quaternary ammonium salt-73 is 0.0001%~0.0005%, bacillus cereus/Semen sojae atricolor Tunning extract, folic acid, hyaluronate sodium and 1,2-hexanediol each 0.5%~2%, xanthan gum 0.1%~0.2%, Radix Arnebiae (Radix Lithospermi) Extract 0.01%~0.5%, Tremella fructification extract 0.0001%~0.0005%, olive oil PEG-7 esters 0.1%~3% is fragrant Essence 0.01%~0.1%, solubilizing agent 0.1%~0.3%, preservative 0.1%~0.3%, surplus is deionized water.
CN201610230096.XA 2016-04-13 2016-04-13 Acne removal essence and preparation method thereof Pending CN105902422A (en)

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CN106511153A (en) * 2016-10-25 2017-03-22 济南佐康商贸有限公司 Nano composition having acne removal function as well as cosmetic or skin care product of nano composition
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CN106265392A (en) * 2016-11-07 2017-01-04 北京痘博士痤疮医学研究院 A kind of health skin purifies essence
CN106727100A (en) * 2016-11-28 2017-05-31 上海珍芙生物科技有限公司 A kind of anti-acne cream composition, acne eliminating cream and preparation method
CN106983692A (en) * 2017-05-19 2017-07-28 广州蜜妆生物科技有限公司 A kind of plant enzyme oil control and acne removal facial mask
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CN110664700B (en) * 2019-11-25 2022-06-24 广州赛莱拉生物基因工程有限公司 Composition and application thereof in preparation of product for preventing and treating acne
CN112370402A (en) * 2020-10-23 2021-02-19 安徽科治医疗科技有限公司 Acne removing gel for regulating cutin
CN112472653A (en) * 2020-12-18 2021-03-12 广州澳梓美生物科技有限公司 Acne-removing aloe gel and preparation method thereof
CN112641680A (en) * 2021-02-05 2021-04-13 东晟源研究院(广州)有限公司 Formula and preparation method of glucan stock solution

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Application publication date: 20160831