CN105395397A - Antibacterial skin care type traditional Chinese medicine composition and application thereof in daily necessities - Google Patents
Antibacterial skin care type traditional Chinese medicine composition and application thereof in daily necessities Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
The invention discloses an antibacterial skin care type traditional Chinese medicine composition and application thereof in daily necessities, and belongs to the field of daily chemical products. The antibacterial skin care type traditional Chinese medicine composition is prepared from, by weight, 1-5 parts of a Chinese mugwort extract and 1 part of a sambong extract; the Chinese mugwort extract and the sambong extract are obtained through extraction by means of a supercritical CO2 extraction technology. According to the antibacterial skin care type traditional Chinese medicine composition, the Chinese mugwort extract and the sambong extract are obtained through extraction by means of the supercritical CO2 extraction technology, the best activity and content of bioactive components of Chinese mugwort and sambong are achieved, and the antibacterial skin care type traditional Chinese medicine composition has the functions of diminishing inflammation, achieving xeransis, promoting collaterals, activating blood, sterilizing and relieving itching through the cooperation and compound effect of Chinese mugwort and sambong. The traditional Chinese medicine composition is mixed with other daily necessity matrixes, the medicine effect of the traditional Chinese medicine composition is not affected, and the obtained daily necessities have the good functions of achieving xeransis, activating blood, resisting bacteria and protecting skin. The antibacterial skin care type traditional Chinese medicine composition is simple in formula, the components are homogenous of medicine and good, and the traditional Chinese medicine is safe, reliable and low in cost.
Description
Technical field
The present invention relates to cosmetics of everyday use field, particularly a kind of antibiotic skin-care type Chinese medicine composition and the application in article of everyday use thereof.
Background technology
In daily life, particularly spring and summer, along with the increase of ambient humidity, antibacterial and virus are easily grown, and are transmitted on human body skin by various communication channel, if do not processed in time it, skin disease can be caused, such as dermatitis, eczema, tinea, acne, dandruff etc.So increasing antibiotic skin-care type article of everyday use becomes the necessary in people's daily life.Common antibiotic skin-care type article of everyday use mostly is antibacterial and the antibacterial of some chemosynthesis, and long-time use easily causes skin dependency, reduces skin to the toleration of antibacterial simultaneously.So, provide a kind of antibiotic skin-care type article of everyday use of safety non-toxic very necessary.
Prior art provides a kind of Chinese medicinal herb antibiotic bacteriostat, is made up of Chinese medicine ingredients such as the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, Rhizoma Alpiniae Officinarum, Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Fructus Gardeniae, Cortex Phellodendri, Ramulus Moris.But inventor finds, the Chinese medicinal herb antibiotic bacteriostat that prior art provides, medicinal herb components is complicated and of a great variety, so not only by increasing the uncertain risk of the Chinese medicinal herb antibiotic bacteriostat formed, also can improve the cost of Chinese medicinal herb antibiotic bacteriostat.
Based on above-mentioned, provide a kind of composition simple, safe and reliable, and cheap antibiotic skin-care type Chinese medicine composition and consisting of article of everyday use have great importance.
Summary of the invention
Embodiment of the present invention technical problem to be solved is, provides a kind of antibiotic skin-care type Chinese medicine composition and the application in article of everyday use thereof.Concrete technical scheme is as follows:
First aspect, embodiments provide a kind of antibiotic skin-care type Chinese medicine composition, this Chinese medicine composition comprises the component of following weight portion: Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract 1-5 part, Herba Blumeae Balsamiferae extract 1 part.Wherein, Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and Herba Blumeae Balsamiferae extract pass through supercritical CO
2abstraction technique extraction obtains.
Particularly, as preferably, the preparation method of described Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and described Herba Blumeae Balsamiferae extract is as follows:
By the mixture of Artemisia argyi Levl. et Van. var. argyi cv. Qiai and Herba Blumeae Balsamiferae and mass concentration be the alcoholic solution of 40-75% according to the quality of 5-8:1 than mixing homogeneously, then extracting pressure be 5-20MPa, extraction temperature is 30-50 DEG C, extraction time carries out supercritical CO under being the condition of 30-240min
2extraction, obtains described Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and described Herba Blumeae Balsamiferae extract.
Second aspect, embodiments provides above-mentioned antibiotic skin-care type Chinese medicine composition and is preparing the application in antibiotic skin-care type article of everyday use.
Particularly, described antibiotic skin-care type article of everyday use is fancy soap, bath foam, liquid detergent, handwashing liquid, shampoo, cleansing milk, facial cream, hands frost, disinfectant, detergent, foot-soaking liquid, bath foam, mosquito is water funk, hair conditioner, Feminine care solution, toothpaste, collutory, air freshener, insecticide, HUOLUO YOU, moxa roll, massage oil, facial film, eye cream, send out film, foot film, quintessence oil soap or body lotion.
The third aspect, embodiments provides a kind of antibiotic skin-care type bath gel, comprises above-mentioned antibiotic skin-care type Chinese medicine composition.
Particularly, as preferably, described bath gel comprises the component of following weight portion: bath gel substrate 100 parts, compositions 5-20 part according to claim 1.
Particularly, described bath gel substrate comprises the component of following weight percentage:
Sodium ethylene diamine tetracetate 0.05-0.15%, acrylic polymer 0.8-1.3%, cocamido propyl betaine 4-7%, Coconut Fatty Acid Monoethanolamide 0.8-1.2%, polyoxyethylenated alcohol sodium sulfate 8-12%, sodium N-lauroyl sarcosinate 4-7%, Polyethylene Glycol-5-lauryl citric acid disodium succinate 8-12%, styrene/acrylamide copolymer 0.25-0.4%, sodium chloride 0.6-1.2%, polydimethylsiloxane 0.9-1.1%, lemon yellow 0.05-0.08%, surplus is deionized water.
Fourth aspect, the embodiment of the present invention additionally provides a kind of antibiotic skin-care type handwashing liquid, comprises the component of following weight portion: handwashing liquid substrate 100 parts, above-mentioned Chinese medicine composition 5-20 part.
5th aspect, the embodiment of the present invention additionally provides a kind of antibiotic skin-care type shampoo, comprises the component of following weight portion: shampoo substrate 100 parts, above-mentioned Chinese medicine composition 5-20 part.
5th aspect, the embodiment of the present invention additionally provides a kind of antibiotic skin-care type emollient cream, comprises the component of following weight portion: emollient cream substrate 100 parts, Chinese medicine composition 5-20 part described in claim 1 or 2.
The beneficial effect that the technical scheme that the embodiment of the present invention provides is brought is:
The antibiotic skin-care type Chinese medicine composition that the embodiment of the present invention provides, passes through supercritical CO
2abstraction technique extraction obtains Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and Herba Blumeae Balsamiferae extract, the activity of the bioactive ingredients of the bioactive ingredients such as volatile oil in Artemisia argyi Levl. et Van. var. argyi cv. Qiai, flavone, triterpenes, vitamin and choline and Herba Blumeae Balsamiferae and content is made to reach best, then the Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract of 1-5 weight portion and the Herba Blumeae Balsamiferae extract of 1 weight portion is adopted to carry out collaborative composite, make this Chinese medicine composition can give full play to the medicinal advantage of each component, have that antiinflammatory dehumidifies, restores menstrual flow and invigorates blood circulation, the function of sterilizing and itch-relieving.Other article of everyday use substrate of this Chinese medicine composition mixed, its drug effect can not be affected, and ensures that the article of everyday use obtained also has good antibacterial functions.Visible, the antibiotic skin-care type Traditional Chinese medicine composition formula that the embodiment of the present invention provides is simple, and each composition integration of edible and medicinal herbs is not only safe and reliable, and with low cost, is convenient to large-scale promotion application.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearly, below embodiment of the present invention is described further in detail.
First aspect, embodiments provide a kind of antibiotic skin-care type Chinese medicine composition, this Chinese medicine composition comprises the component of following weight portion: Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract 1-5 part, Herba Blumeae Balsamiferae extract 1 part.Wherein, Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and Herba Blumeae Balsamiferae extract pass through supercritical CO
2abstraction technique extraction obtains.
The embodiment of the present invention provide for antibiotic skin-care type Chinese medicine composition, pass through supercritical CO
2abstraction technique extraction obtains Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and Herba Blumeae Balsamiferae extract, the activity of the bioactive ingredients of the bioactive ingredients such as volatile oil in Artemisia argyi Levl. et Van. var. argyi cv. Qiai, flavone, triterpenes, vitamin and choline and Herba Blumeae Balsamiferae and content is made to reach best, then the Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract of 1-5 weight portion and the Herba Blumeae Balsamiferae extract of 1 weight portion is adopted to carry out collaborative composite, make this Chinese medicine composition can give full play to the medicinal advantage of each component, have that antiinflammatory dehumidifies, restores menstrual flow and invigorates blood circulation, the function of sterilizing and itch-relieving.Other article of everyday use substrate of this Chinese medicine composition mixed, its drug effect can not be affected, and ensures that the article of everyday use obtained also has good antibacterial functions.Visible, the antibiotic skin-care type composite formula that the embodiment of the present invention provides is simple, and each composition integration of edible and medicinal herbs is not only safe and reliable, and with low cost, is convenient to large-scale promotion application.
Wherein, " Artemisia argyi Levl. et Van. var. argyi cv. Qiai " described in the embodiment of the present invention refers in particular to originate from Qichun County, Hubei Province, and the Artemisia argyi Levl. et Van. var. argyi cv. Qiai of gathering before the time Dragon Boat Festival, reach best with the activity and content that ensure wherein contained bioactie agent.
Folium Artemisiae Argyi, has another name called Artemisia argyi, Radix Artemisia ordosicae, is the perennial wild herb of Compositae artemisia.Folium Artemisiae Argyi has very high medical value, is China's Chinese medicine.Among the people in China, also spread the proverb of " there are 3 years Chinese mugworts in family, and doctor is not used for " so far, more have many places to plant Folium Artemisiae Argyi in every family, every household collection Folium Artemisiae Argyi.Mencius says: the disease of 7 years, asks the Chinese mugwort of 3 years.The height of its pharmacological function visible.Motherland's Chinese medicine history is early on the books: Folium Artemisiae Argyi is the natural plants that a kind of medical value is very high, is one of China working people understanding and application Traditional chinese medicine medicament comparatively early.Compendium of Material Medica is recorded: Folium Artemisiae Argyi has the effect of getting rid of evils, purifying; The function of promoting flow of qi by warming channel, pain relieving of dispeling cold, looks improving and the skin nourishing, slow down aging.Wherein, originate from Qichun County, Hubei Province, and the Artemisia argyi Levl. et Van. var. argyi cv. Qiai of gathering before the time Dragon Boat Festival receives much concern based on this good anti-inflammation function.The main chemical compositions of Artemisia argyi Levl. et Van. var. argyi cv. Qiai has volatile oil, eudesmane, triterpenes, flavonoid and various trace elements.Wherein, volatile oil contains the effective ingredient of broad-spectrum sterilization, such as eucalyptol, Camphora etc., and to aquatile encountered pathogenic bacteria, such as anthrax bacillus, staphylococcus aureus and escherichia coli have stronger bacteriostasis; The composition such as flavonoid, triterpenes has certain antioxidation; Flavone compound has the multiple physiological activities such as blood fat reducing, antithrombotic, antioxidation, blood sugar lowering, antitumor, enhancing immunity, slow down aging and treatment chronic prostatitis.
Herba Blumeae Balsamiferae, function cures mainly: warming middle-JIAO is invigorated blood circulation, expelling wind and removing dampness, parasite killing; Control cold-damp dysentery, stomachache borborygmus, swelling, bones and muscles pain, traumatic injury, tinea skin ulcer." Haiyao Bencao, Oversea Materia Medica ": main typhoid fever five kinds of diarrhea, trusted subordinate's gas injection, lower cun is white, only borborygmus, burning ward off pestilence." Kaibao Bencao ": remove bad odor, parasite killing, main abdomen is cold lets out dysentery." the SHENGCAO property of medicine is standby to be wanted ": detumescence of dispeling the wind, dehumidifying of invigorating blood circulation, controls traumatic injury, applies wind syndrome due to invasion of wind when drinking foot." south of the Five Ridges gather medicinal herbs record ": treat extremity osteodynia.
As preferably, the embodiment of the present invention passes through supercritical CO
2abstraction technique extracts Artemisia argyi Levl. et Van. var. argyi cv. Qiai and Herba Blumeae Balsamiferae, and obtain Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and Herba Blumeae Balsamiferae extract, concrete preparation method is as follows:
Be 40-75% by the mixture of Artemisia argyi Levl. et Van. var. argyi cv. Qiai and Herba Blumeae Balsamiferae and mass concentration, the alcoholic solution being preferably 50% according to the quality of 5-8:1 than mix homogeneously, then extracting pressure be 5-20MPa, extraction temperature is 30-50 DEG C, extraction time carries out supercritical CO under being the condition of 30-240min
2extraction, obtains Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and Herba Blumeae Balsamiferae extract.
The embodiment of the present invention is by adopting as above extracting method, the destruction to bioactie agent in Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and Herba Blumeae Balsamiferae extract can be reduced as far as possible, and improve extraction ratio as far as possible, ensure that the activity of the bioactive ingredients of the bioactive ingredients such as volatile oil, flavone, triterpenes, vitamin and choline in Artemisia argyi Levl. et Van. var. argyi cv. Qiai and Herba Blumeae Balsamiferae and content reach best.For example, at supercritical CO
2in extraction process, its extracting pressure can be 5MPa, 8MPa, 10MPa, 12MPa, 14MPa, 17MPa, 20MPa etc., its extraction temperature can be 30 DEG C, 32 DEG C, 35 DEG C, 37 DEG C, 40 DEG C, 42 DEG C, 45 DEG C, 47 DEG C, 49 DEG C etc., and extraction time can be 30min, 50min, 70min, 100min, 120min, 140min, 160min, 180min, 200min, 220min, 240min etc.
Second aspect, embodiments provides above-mentioned antibiotic skin-care type Chinese medicine composition and is preparing the application in antibiotic skin-care type article of everyday use.Particularly, this antibiotic skin-care type article of everyday use is fancy soap, bath foam, liquid detergent, handwashing liquid, shampoo, cleansing milk, facial cream, hands frost, disinfectant, detergent, foot-soaking liquid, bath foam, mosquito is water funk, hair conditioner, Feminine care solution, toothpaste, collutory, air freshener, insecticide, HUOLUO YOU, moxa roll, massage oil, facial film, eye cream, send out film, foot film, quintessence oil soap or body lotion, or other skin and hair article of everyday use.
The third aspect, the embodiment of the present invention specifically provides a kind of antibiotic skin-care type bath gel, comprises above-mentioned antibiotic skin-care type Chinese medicine composition.Particularly, this bath gel comprises the component of following weight portion: bath gel substrate 100 parts, above-mentioned Chinese medicine composition 5-20 part.Wherein, this bath gel substrate comprises the component of following weight percentage:
Sodium ethylene diamine tetracetate 0.05-0.15%, acrylic polymer 0.8-1.3%, cocamido propyl betaine 4-7%, Coconut Fatty Acid Monoethanolamide 0.8-1.2%, polyoxyethylenated alcohol sodium sulfate 8-12%, sodium N-lauroyl sarcosinate 4-7%, Polyethylene Glycol-5-lauryl citric acid disodium succinate 8-12%, styrene/acrylamide copolymer 0.25-0.4%, sodium chloride 0.6-1.2%, polydimethylsiloxane 0.9-1.1%, lemon yellow 0.05-0.08%, surplus is deionized water.
As preferably, in this bath gel substrate, the percentage by weight of each component is as follows: sodium ethylene diamine tetracetate 0.1%, acrylic polymer 1%, cocamido propyl betaine 5%, Coconut Fatty Acid Monoethanolamide 1%, polyoxyethylenated alcohol sodium sulfate 10%, sodium N-lauroyl sarcosinate 5%, Polyethylene Glycol-5-lauryl citric acid disodium succinate 10%, styrene/acrylamide copolymer 0.3%, sodium chloride 0.9%, polydimethylsiloxane 1%, lemon yellow 0.075%, surplus are deionized water.
Particularly, in above-mentioned each component, sodium ethylene diamine tetracetate (i.e. EDTA), acrylic polymer (such as SF-1 type acrylic polymer), cocamido propyl betaine (i.e. CAB), Coconut Fatty Acid Monoethanolamide (i.e. CMEA), polyoxyethylenated alcohol sodium sulfate (such as AES-70 sodium), sodium N-lauroyl sarcosinate (such as the sodium N-lauroyl sarcosinate of LS-30N type), Polyethylene Glycol-5-lauryl citric acid disodium succinate (Polyethylene Glycol-5-lauryl citric acid disodium succinate of such as MESD30 type), styrene/acrylamide copolymer (such as OP-303 type styrene/acrylamide copolymer), sodium chloride, polydimethylsiloxane, lemon yellow is the conventional commodity raw material in this area, those skilled in the art easily can be obtained by the mode made by oneself or buy.
Be understandable that, Chinese medicine composition that the embodiment of the present invention provides can also be used alone or be joined in conventional article of everyday use mixed, to reach good bactericidal and bacteriostatic effect.
Particularly, the 5th aspect, the embodiment of the present invention additionally provides a kind of antibiotic skin-care type handwashing liquid, comprises the component of following weight portion: handwashing liquid substrate 100 parts, above-mentioned Chinese medicine composition 5-20 part.Wherein the formula of handwashing liquid substrate is as shown in table 1:
Table 1
6th aspect, the embodiment of the present invention additionally provides a kind of antibiotic skin-care type shampoo, comprises the component of following weight portion: shampoo substrate 100 parts, above-mentioned Chinese medicine composition 5-20 part.Wherein the formula of shampoo substrate is as shown in table 2:
Table 2
| Shampoo substrate | Percentage by weight (%) |
| Disodiumedetate | 0.1 |
| Cation guar gum | 0.2-0.4 |
| Polyquaternium-10 | 0.2-0.4 |
| Cocamido propyl betaine | 5.0-8.0 |
| Sodium lauroyl sarcosine | 3.0-5.0 |
| Fatty alcohol ether ammonium sulfate | 10.0-15.0 |
| Ammonium lauryl sulfate | 5.0-10.0 |
| Coconut monoethanol amide | 1.5‐2.5 |
| Ethylene Glycol Distearate | 1.0‐2.0 |
| Cetearyl alcohol | 0.3‐0.5 |
| Citric acid | 0.04-0.1 |
| Polydimethylsiloxane | 2.0-4.0 |
| Sodium lactate | 2.0-3.0 |
| Methylchloroisothiazandnone | 0.2-2％ |
| Essence | 0.01-1％ |
| Deionized water | Surplus |
7th aspect, the embodiment of the present invention additionally provides a kind of antibiotic skin-care type emollient cream, comprises the component of following weight portion: emollient cream substrate 100 parts, above-mentioned Chinese medicine composition 5-20 part.Wherein the formula of emollient cream substrate is as shown in table 3:
Table 3
| Emollient cream substrate | Percentage by weight (%) |
| C12-20 alkyl androstanediol | 2.0-3.0 |
| Glyceryl stearate | 1.0-2.0 |
| Cetearyl alcohol | 2.0-4.0 |
| Isononyl isononanoate | 2.0-5.0 |
| Tridecyl alcohol stearate | 2.0-3.0 |
| Parleam | 2.0-3.0 |
| Polydimethylsiloxane | 2.0-4.0 |
| American Avocado Tree oil | 2.0-3.0 |
| Butyrospermum Parkii Oil | 2.0-4.0 |
| Jojoba seed oil | 1.0-3.0 |
| Vitamin E acetate | 0.5-1.0 |
| Essence | 0.01-0.1 |
| Deionized water | Surplus |
| Glycerol | 3.0-6.0 |
| 1.3-butanediol | 4.0-8.0 |
| Hyaluronate sodium | 0.05-0.1 |
| Betanin | 1.0-5.0 |
| Nicotiamide | 1.0-2.0 |
| Trehalose | 1.0-3.0 |
| Phenoxyethanol | 0.5-0.8 |
| Carbomer | 0.2-0.3 |
| Triethanolamine | 0.2-0.3 |
Below further the present invention will be described by specific embodiment.In following specific embodiment, the unreceipted condition person of involved operation, the condition of all conveniently condition or manufacturer's suggestion is carried out.Raw materials used unreceipted production firm and specification person are can by the conventional products of commercial acquisition.Involved Artemisia argyi Levl. et Van. var. argyi cv. Qiai refers in particular to and originates from Qichun County, Hubei Province, and the Artemisia argyi Levl. et Van. var. argyi cv. Qiai of gathering before the time Dragon Boat Festival.
Embodiment 1
Present embodiments provide a kind of antibiotic skin-care type Chinese medicine composition, this Chinese medicine composition comprises the component of following weight portion: Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract 1 part, Herba Blumeae Balsamiferae extract 1 part.
This Chinese medicine composition prepares by the following method:
According to the weight proportion of component each in Chinese medicine composition, by the mixture of Artemisia argyi Levl. et Van. var. argyi cv. Qiai and Herba Blumeae Balsamiferae and mass concentration be 50% alcoholic solution according to the quality of 6:1 than mixing homogeneously, then extracting pressure be 15MPa, extraction temperature is 40 DEG C, extraction time carries out supercritical CO under being the condition of 30-240min
2extraction, obtains Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and Herba Blumeae Balsamiferae extract.
Embodiment 2
Present embodiments provide a kind of antibiotic skin-care type Chinese medicine composition, this Chinese medicine composition comprises the component of following weight portion: Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract 2 parts, Herba Blumeae Balsamiferae extract 1 part.
This Chinese medicine composition prepares by the following method:
According to the weight proportion of component each in Chinese medicine composition, by the mixture of Artemisia argyi Levl. et Van. var. argyi cv. Qiai and Herba Blumeae Balsamiferae and mass concentration be 40% alcoholic solution according to the quality of 7:1 than mixing homogeneously, then extracting pressure be 5MPa, extraction temperature is 45 DEG C, extraction time carries out supercritical CO under being the condition of 150min
2extraction, obtains Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and Herba Blumeae Balsamiferae extract.
Embodiment 3
Present embodiments provide a kind of antibiotic skin-care type Chinese medicine composition, this Chinese medicine composition comprises the component of following weight portion: Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract 3 parts, Herba Blumeae Balsamiferae extract 1 part.
This Chinese medicine composition prepares by the following method:
According to the weight proportion of component each in Chinese medicine composition, by the mixture of Artemisia argyi Levl. et Van. var. argyi cv. Qiai and Herba Blumeae Balsamiferae and mass concentration be 60% alcoholic solution according to the quality of 8:1 than mixing homogeneously, then extracting pressure be 20MPa, extraction temperature is 30 DEG C, extraction time carries out supercritical CO under being the condition of 240min
2extraction, obtains Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and Herba Blumeae Balsamiferae extract.
Embodiment 4
Present embodiments provide a kind of antibiotic skin-care type Chinese medicine composition, this Chinese medicine composition comprises the component of following weight portion: Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract 4 parts, Herba Blumeae Balsamiferae extract 1 part.
This Chinese medicine composition prepares by the following method:
According to the weight proportion of component each in Chinese medicine composition, by the mixture of Artemisia argyi Levl. et Van. var. argyi cv. Qiai and Herba Blumeae Balsamiferae and mass concentration be 40% alcoholic solution according to the quality of 5:1 than mixing homogeneously, then extracting pressure be 10MPa, extraction temperature is 50 DEG C, extraction time carries out supercritical CO under being the condition of 30min
2extraction, obtains Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and Herba Blumeae Balsamiferae extract.
Embodiment 5
Present embodiments provide a kind of bath gel, comprise the component of following weight portion: the Chinese medicine composition that bath gel substrate 100 parts, embodiment 3 provide 5 parts.
Wherein, bath gel substrate is selected from the Liushen Shower Gel that Shanghai Fine Chemical Co., Ltd sells.
Embodiment 6
Present embodiments provide a kind of bath gel, comprise the component of following weight portion: the Chinese medicine composition that bath gel substrate 1000 parts, embodiment 1 provide 75 parts.
Wherein, the percentage by weight of each component of bath gel substrate is as follows: sodium ethylene diamine tetracetate 0.1%, acrylic polymer 1%, cocamido propyl betaine 5%, Coconut Fatty Acid Monoethanolamide 1%, polyoxyethylenated alcohol sodium sulfate 10%, sodium N-lauroyl sarcosinate 5%, Polyethylene Glycol-5-lauryl citric acid disodium succinate 10%, styrene/acrylamide copolymer 0.3%, sodium chloride 0.9%, polydimethylsiloxane 1%, lemon yellow 0.075%, surplus are deionized water.
Embodiment 7
Present embodiments provide a kind of bath gel, comprise the component of following weight portion: the Chinese medicine composition that bath gel substrate 100 parts, embodiment 2 provide 10 parts.
Wherein, the percentage by weight of each component of bath gel substrate is as follows: sodium ethylene diamine tetracetate 0.12%, acrylic polymer 0.9%, cocamido propyl betaine 6%, Coconut Fatty Acid Monoethanolamide 1.1%, polyoxyethylenated alcohol sodium sulfate 12%, sodium N-lauroyl sarcosinate 4%, Polyethylene Glycol-5-lauryl citric acid disodium succinate 9%, styrene/acrylamide copolymer 0.3%, sodium chloride 1%, polydimethylsiloxane 1%, lemon yellow 0.06%, surplus are deionized water.
Embodiment 8
Present embodiments provide a kind of bath gel, comprise the component of following weight portion: the Chinese medicine composition that bath gel substrate 100 parts, embodiment 4 provide 8 parts.
Wherein, the percentage by weight of each component of bath gel substrate is as follows: sodium ethylene diamine tetracetate 0.08%, acrylic polymer 0.8%, cocamido propyl betaine 4%, Coconut Fatty Acid Monoethanolamide 1%, polyoxyethylenated alcohol sodium sulfate 8%, sodium N-lauroyl sarcosinate 6%, Polyethylene Glycol-5-lauryl citric acid disodium succinate 8%, styrene/acrylamide copolymer 0.3%, sodium chloride 0.65%, polydimethylsiloxane 0.95%, lemon yellow 0.07%, surplus are deionized water.
Embodiment 9
Present embodiments provide a kind of handwashing liquid, comprise the component of following weight portion: the Chinese medicine composition that handwashing liquid substrate 100 parts, embodiment 1 provide 10 parts.
Wherein, in handwashing liquid substrate, the percentage by weight of each component is as follows: disodiumedetate 0.1%, fatty alcohol-ether sodium sulfate 12%, cocamido propyl betaine 6%, sodium lauroyl glutamate 4%, laurylglutamic potassium 3%, coconut monoethanol amide 1%, sodium chloride 0.8%, salicylic acid 0.2%, triclosan 0.2%, glycerol 4%, fatty alcohol-polyoxyethylene ether disodium sulfosuccinate salt 8%, essence 0.05%, surplus are water.
Embodiment 10
Present embodiments provide a kind of shampoo, comprise the component of following weight portion: the Chinese medicine composition that shampoo substrate 100 parts, embodiment 1 provide 10 parts.
Wherein, in handwashing liquid substrate, the percentage by weight of each component is as follows: disodiumedetate 0.1%, cation guar gum 0.3%, Polyquaternium-10 0.2%, cocamido propyl betaine 6%, sodium lauroyl sarcosine 5%, fatty alcohol ether ammonium sulfate 12%, ammonium lauryl sulfate 8%, coconut monoethanol amide 2%, Ethylene Glycol Distearate 1.5%, cetearyl alcohol 0.25%, citric acid 0.05%, polydimethylsiloxane 3%, sodium lactate 2.5%, methylchloroisothiazandnone 1%, essence 0.03%, surplus are deionized water.
Embodiment 11
Present embodiments provide a kind of emollient cream, comprise the component of following weight portion: the Chinese medicine composition that emollient cream substrate 100 parts, embodiment 1 provide 10 parts.
Wherein, in emollient cream substrate, the percentage by weight of each component is as follows: C12-20 alkyl androstanediol 2.5%, glyceryl stearate 1.5%, cetearyl alcohol 3%, isononyl isononanoate 3%, tridecyl alcohol stearate 2.5%, Parleam 2.5%, polydimethylsiloxane 2.5%, American Avocado Tree oil 3%, shea fruit oil 4%, Jojoba seed oil 2%, Vitamin E acetate 0.6%, glycerol 3.5%, 1, 3-butanediol 5%, hyaluronate sodium 0.08%, betanin 5%, nicotiamide 1.5%, trehalose 2%, phenoxyethanol 0.6%, carbomer 0.25%, triethanolamine 0.2%, essence 0.1%, surplus is deionized water.
Embodiment 12
The Chinese medicine composition that this enforcement at random utilizes embodiment 1-4 to provide, the bath gel that embodiment 5-8 provides, the handwashing liquid that embodiment 9 provides, the shampoo that embodiment 10 provides and emollient cream that embodiment 11 provides are tested for there being the crowd of skin bacteriostatic treatments demand, to investigate the antibacterial effect of above product.Wherein, the skin condition of above-mentioned crowd is unstable, time have pruritus, inflammation or eczema symptom.
1, study subject and method
1.1 study subjects: normal men and women experimenter 50 people of age between 18-60 year, preferred women; In the past to skin care item without allergies; Hormone medicine and immunoreagent person had not been used in nearly one month.
1.2 subject method: using face or extremity as tested region, apply above compositions or bath gel 10-20 minute is advisable in above tested region, the persistent period is 30 days.Experimenter can not use other products (such as cosmetics, topical drug or health product) with white-skinned face function tested period.
1.3 tested effect assessments: antibacterial effect is evaluated by the sensory experience of experimenter.
2, experimental result:
Carried out sensory testing to above experimenter, test result is divided into does not have the general and successful Three Estate of effect, effect.Wherein, effect and subjects skin's pruritus, inflammation or eczema phenomenon is not had still often to show effect; Effect generally namely experimenter experience skin pruritus, inflammation or eczema phenomenon and make moderate progress, its seizure frequency obviously reduces before comparatively testing, and skin condition is stablized; No longer there is skin pruritus, inflammation or eczema phenomenon in successful and experimenter, and skin-tolerant strengthens, and skin condition is highly stable.Result shows, and in 50 experimenters, effect is general to have 5 people to reflect, all the other all reflect successful.The skin condition of above experimenter all keeps good steady statue at test period, and moist degree, moisturizing degree and comfort level all have excellent feedback.
The foregoing is only preferred embodiment of the present invention, not in order to limit the scope of the invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. an antibiotic skin-care type Chinese medicine composition, is characterized in that, described Chinese medicine composition comprises the component of following weight portion: Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract 1-5 part, Herba Blumeae Balsamiferae extract 1 part;
Described Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and described Herba Blumeae Balsamiferae extract pass through supercritical CO
2abstraction technique extraction obtains.
2. antibiotic skin-care type Chinese medicine composition according to claim 1, is characterized in that, the preparation method of described Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and described Herba Blumeae Balsamiferae extract is as follows:
By the mixture of Artemisia argyi Levl. et Van. var. argyi cv. Qiai and Herba Blumeae Balsamiferae and mass concentration be the alcoholic solution of 40-75% according to the quality of 5-8:1 than mixing homogeneously, then extracting pressure be 5-20MPa, extraction temperature is 30-50 DEG C, extraction time carries out supercritical CO under being the condition of 30-240min
2extraction, obtains described Artemisia argyi Levl. et Van. var. argyi cv. Qiai extract and described Herba Blumeae Balsamiferae extract.
3. the antibiotic skin-care type Chinese medicine composition described in claim 1 or 2 is preparing the application in antibiotic skin-care type article of everyday use.
4. application according to claim 3, it is characterized in that, described antibiotic skin-care type article of everyday use is fancy soap, bath foam, liquid detergent, handwashing liquid, shampoo, cleansing milk, facial cream, hands frost, disinfectant, detergent, foot-soaking liquid, bath foam, mosquito is water funk, hair conditioner, Feminine care solution, toothpaste, collutory, air freshener, insecticide, HUOLUO YOU, moxa roll, massage oil, facial film, eye cream, send out film, foot film, quintessence oil soap or body lotion.
5. an antibiotic skin-care type bath gel, comprises the antibiotic skin-care type Chinese medicine composition described in claim 1 or 2.
6. bath gel according to claim 5, is characterized in that, described bath gel comprises the component of following weight portion: bath gel substrate 100 parts, Chinese medicine composition 5-20 part described in claim 1 or 2.
7. bath gel according to claim 6, is characterized in that, described bath gel substrate comprises the component of following weight percentage:
Sodium ethylene diamine tetracetate 0.05-0.15%, acrylic polymer 0.8-1.3%, cocamido propyl betaine 4-7%, Coconut Fatty Acid Monoethanolamide 0.8-1.2%, polyoxyethylenated alcohol sodium sulfate 8-12%, sodium N-lauroyl sarcosinate 4-7%, Polyethylene Glycol-5-lauryl citric acid disodium succinate 8-12%, styrene/acrylamide copolymer 0.25-0.4%, sodium chloride 0.6-1.2%, polydimethylsiloxane 0.9-1.1%, lemon yellow 0.05-0.08%, surplus is deionized water.
8. an antibiotic skin-care type handwashing liquid, comprises the component of following weight portion: handwashing liquid substrate 100 parts, Chinese medicine composition 5-20 part described in claim 1 or 2.
9. an antibiotic skin-care type shampoo, comprises the component of following weight portion: shampoo substrate 100 parts, Chinese medicine composition 5-20 part described in claim 1 or 2.
10. an antibiotic skin-care type emollient cream, comprises the component of following weight portion: emollient cream substrate 100 parts, Chinese medicine composition 5-20 part described in claim 1 or 2.
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| CN201510849787.3A CN105395397A (en) | 2015-11-27 | 2015-11-27 | Antibacterial skin care type traditional Chinese medicine composition and application thereof in daily necessities |
| HK16104107.4A HK1216605A1 (en) | 2015-11-27 | 2016-04-11 | Antibacterial skin care product with chinese herbal preparation and its application in daily use |
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| CN201510849787.3A CN105395397A (en) | 2015-11-27 | 2015-11-27 | Antibacterial skin care type traditional Chinese medicine composition and application thereof in daily necessities |
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| CN106913602A (en) * | 2017-01-24 | 2017-07-04 | 中国热带农业科学院热带作物品种资源研究所 | A kind of Blumea balsamifera gynaecologic washing lotion and its preparation method and application |
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| CN110917076A (en) * | 2018-09-19 | 2020-03-27 | 中国医学科学院药用植物研究所 | Plant bath foam for children |
| CN109594196A (en) * | 2018-11-07 | 2019-04-09 | 桐城市鸿江包装有限公司 | The preparation method of antimicrobial form wall paper non-woven fabrics |
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| CN110292556A (en) * | 2019-07-03 | 2019-10-01 | 深圳市艾一生命科技有限公司 | Mescenchymal stem cell excretion group combination preparation and preparation method and application |
| CN114306404A (en) * | 2020-09-30 | 2022-04-12 | 贵州宏宇药业有限公司 | A herba Blumeae Balsamiferae extract with anti-influenza virus effect, and its preparation method |
| CN114732745A (en) * | 2022-04-14 | 2022-07-12 | 杭州鲸护卫纳米科技有限公司 | Nano-silver antibacterial hand sanitizer and preparation method thereof |
| CN114732745B (en) * | 2022-04-14 | 2023-08-22 | 杭州鲸护卫纳米科技有限公司 | Nano-silver antibacterial hand sanitizer and preparation method thereof |
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