CN105901464A - 一种具有辅助降血脂功效的泡腾片饮料 - Google Patents
一种具有辅助降血脂功效的泡腾片饮料 Download PDFInfo
- Publication number
- CN105901464A CN105901464A CN201610289380.4A CN201610289380A CN105901464A CN 105901464 A CN105901464 A CN 105901464A CN 201610289380 A CN201610289380 A CN 201610289380A CN 105901464 A CN105901464 A CN 105901464A
- Authority
- CN
- China
- Prior art keywords
- parts
- acid
- chinese medical
- auxiliary lipid
- lowering efficacy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000013361 beverage Nutrition 0.000 title claims abstract description 25
- 239000007938 effervescent tablet Substances 0.000 title claims abstract description 10
- 210000004369 blood Anatomy 0.000 title abstract description 18
- 239000008280 blood Substances 0.000 title abstract description 18
- 150000002632 lipids Chemical class 0.000 title abstract description 5
- 240000002234 Allium sativum Species 0.000 claims abstract description 27
- 235000004611 garlic Nutrition 0.000 claims abstract description 26
- 235000003145 Hippophae rhamnoides Nutrition 0.000 claims abstract description 16
- 240000000950 Hippophae rhamnoides Species 0.000 claims abstract description 15
- 239000000284 extract Substances 0.000 claims abstract description 7
- 239000000314 lubricant Substances 0.000 claims abstract description 5
- 239000003755 preservative agent Substances 0.000 claims abstract description 5
- 239000000796 flavoring agent Substances 0.000 claims abstract description 4
- 235000019634 flavors Nutrition 0.000 claims abstract description 4
- 239000003795 chemical substances by application Substances 0.000 claims abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 38
- 239000003826 tablet Substances 0.000 claims description 20
- 241001116389 Aloe Species 0.000 claims description 16
- 244000037364 Cinnamomum aromaticum Species 0.000 claims description 16
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims description 16
- 240000002853 Nelumbo nucifera Species 0.000 claims description 16
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims description 16
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims description 16
- 235000011399 aloe vera Nutrition 0.000 claims description 16
- 235000009917 Crataegus X brevipes Nutrition 0.000 claims description 12
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 claims description 12
- 235000009685 Crataegus X maligna Nutrition 0.000 claims description 12
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 claims description 12
- 235000009486 Crataegus bullatus Nutrition 0.000 claims description 12
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 claims description 12
- 235000009682 Crataegus limnophila Nutrition 0.000 claims description 12
- 235000004423 Crataegus monogyna Nutrition 0.000 claims description 12
- 235000002313 Crataegus paludosa Nutrition 0.000 claims description 12
- 235000009840 Crataegus x incaedua Nutrition 0.000 claims description 12
- 239000002253 acid Substances 0.000 claims description 11
- 238000000227 grinding Methods 0.000 claims description 11
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 10
- 239000007788 liquid Substances 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 239000012141 concentrate Substances 0.000 claims description 9
- 238000001035 drying Methods 0.000 claims description 9
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 8
- 239000002245 particle Substances 0.000 claims description 7
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 6
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical group [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 6
- 239000011734 sodium Substances 0.000 claims description 6
- 229910052708 sodium Inorganic materials 0.000 claims description 6
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 6
- 239000004299 sodium benzoate Substances 0.000 claims description 6
- 235000010234 sodium benzoate Nutrition 0.000 claims description 6
- 235000005979 Citrus limon Nutrition 0.000 claims description 5
- 244000131522 Citrus pyriformis Species 0.000 claims description 5
- 235000011430 Malus pumila Nutrition 0.000 claims description 5
- 235000015103 Malus silvestris Nutrition 0.000 claims description 5
- 239000011780 sodium chloride Substances 0.000 claims description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 4
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 claims description 4
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 claims description 4
- 230000002335 preservative effect Effects 0.000 claims description 4
- 239000002994 raw material Substances 0.000 claims description 4
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 3
- 241000675108 Citrus tangerina Species 0.000 claims description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 3
- 240000008790 Musa x paradisiaca Species 0.000 claims description 3
- 235000018290 Musa x paradisiaca Nutrition 0.000 claims description 3
- 239000003513 alkali Substances 0.000 claims description 3
- 239000007884 disintegrant Substances 0.000 claims description 3
- 239000001530 fumaric acid Substances 0.000 claims description 3
- 229960003511 macrogol Drugs 0.000 claims description 3
- 239000004302 potassium sorbate Substances 0.000 claims description 3
- 235000010241 potassium sorbate Nutrition 0.000 claims description 3
- 229940069338 potassium sorbate Drugs 0.000 claims description 3
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 3
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 3
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 2
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 2
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 2
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 2
- 244000290333 Vanilla fragrans Species 0.000 claims description 2
- 235000009499 Vanilla fragrans Nutrition 0.000 claims description 2
- 235000012036 Vanilla tahitensis Nutrition 0.000 claims description 2
- 239000000853 adhesive Substances 0.000 claims description 2
- 230000001070 adhesive effect Effects 0.000 claims description 2
- 239000001361 adipic acid Substances 0.000 claims description 2
- 235000011037 adipic acid Nutrition 0.000 claims description 2
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 2
- 150000001413 amino acids Chemical class 0.000 claims description 2
- 239000011575 calcium Substances 0.000 claims description 2
- 229910052791 calcium Inorganic materials 0.000 claims description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 2
- 235000011087 fumaric acid Nutrition 0.000 claims description 2
- 239000001630 malic acid Substances 0.000 claims description 2
- 235000011090 malic acid Nutrition 0.000 claims description 2
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims description 2
- 229940041616 menthol Drugs 0.000 claims description 2
- TZBAVQKIEKDGFH-UHFFFAOYSA-N n-[2-(diethylamino)ethyl]-1-benzothiophene-2-carboxamide;hydrochloride Chemical group [Cl-].C1=CC=C2SC(C(=O)NCC[NH+](CC)CC)=CC2=C1 TZBAVQKIEKDGFH-UHFFFAOYSA-N 0.000 claims description 2
- 235000019477 peppermint oil Nutrition 0.000 claims description 2
- 229910000027 potassium carbonate Inorganic materials 0.000 claims description 2
- 238000010298 pulverizing process Methods 0.000 claims description 2
- 239000011975 tartaric acid Substances 0.000 claims description 2
- 235000002906 tartaric acid Nutrition 0.000 claims description 2
- 240000000171 Crataegus monogyna Species 0.000 claims 4
- 239000000463 material Substances 0.000 claims 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims 2
- 241000196324 Embryophyta Species 0.000 claims 1
- 229910021529 ammonia Inorganic materials 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 8
- 239000000945 filler Substances 0.000 abstract description 2
- 244000003416 Asparagus officinalis Species 0.000 abstract 1
- 235000005340 Asparagus officinalis Nutrition 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 230000035764 nutrition Effects 0.000 abstract 1
- 210000000582 semen Anatomy 0.000 abstract 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 20
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid group Chemical group C(CC(O)(C(=O)O)CC(=O)O)(=O)O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 12
- 235000012000 cholesterol Nutrition 0.000 description 10
- 241001092040 Crataegus Species 0.000 description 8
- 210000004204 blood vessel Anatomy 0.000 description 7
- 108090001030 Lipoproteins Proteins 0.000 description 5
- 102000004895 Lipoproteins Human genes 0.000 description 5
- 239000004480 active ingredient Substances 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 238000000605 extraction Methods 0.000 description 5
- 201000005577 familial hyperlipidemia Diseases 0.000 description 5
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 4
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 4
- 235000015165 citric acid Nutrition 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 4
- 239000008101 lactose Substances 0.000 description 4
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 4
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 4
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 3
- 239000005711 Benzoic acid Substances 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 229930195725 Mannitol Natural products 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 235000010233 benzoic acid Nutrition 0.000 description 2
- 230000036770 blood supply Effects 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 238000004090 dissolution Methods 0.000 description 2
- 230000002526 effect on cardiovascular system Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 238000002386 leaching Methods 0.000 description 2
- 239000000594 mannitol Substances 0.000 description 2
- 235000010355 mannitol Nutrition 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 150000003626 triacylglycerols Chemical class 0.000 description 2
- DWNBOPVKNPVNQG-LURJTMIESA-N (2s)-4-hydroxy-2-(propylamino)butanoic acid Chemical compound CCCN[C@H](C(O)=O)CCO DWNBOPVKNPVNQG-LURJTMIESA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 108010004103 Chylomicrons Proteins 0.000 description 1
- 240000009087 Crescentia cujete Species 0.000 description 1
- 235000005983 Crescentia cujete Nutrition 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- 206010016654 Fibrosis Diseases 0.000 description 1
- 206010017577 Gait disturbance Diseases 0.000 description 1
- 208000007882 Gastritis Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 241000229143 Hippophae Species 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 201000001431 Hyperuricemia Diseases 0.000 description 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 description 1
- 235000009797 Lagenaria vulgaris Nutrition 0.000 description 1
- 206010033645 Pancreatitis Diseases 0.000 description 1
- 208000018262 Peripheral vascular disease Diseases 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 244000041790 Spanish garlic Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 208000007107 Stomach Ulcer Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 206010042434 Sudden death Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003143 atherosclerotic effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 201000001883 cholelithiasis Diseases 0.000 description 1
- 208000023652 chronic gastritis Diseases 0.000 description 1
- 230000007882 cirrhosis Effects 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 208000000718 duodenal ulcer Diseases 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 239000010647 garlic oil Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 210000004051 gastric juice Anatomy 0.000 description 1
- 210000001156 gastric mucosa Anatomy 0.000 description 1
- 201000005917 gastric ulcer Diseases 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920006316 polyvinylpyrrolidine Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/40—Effervescence-generating compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
- A23L2/395—Dry compositions in a particular shape or form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
本发明提供一种具有辅助降血脂功效的泡腾片饮料，所述泡腾片饮料包括以下重量份的原料：可食用中药浸膏3～15份、崩解剂43～65份、润滑剂1～13份、填充剂2～10份、粘合剂1～8份、矫味剂0.5～3份、防腐剂0.5～2份，所述可食用中药浸膏为8～35份大蒜、6～30份沙棘、6～30份芦荟、3～20份荷叶、1～15份决明子的混合提取物。本发明泡腾片饮料采用可食用中药提取浸膏制备而成，营养丰富、口味独特、携带方便、易于溶解、冷溶热溶皆可，且生物利用度高、稳定性好，易于贮存，具有显著的辅助降血脂功效。
Description
技术领域
本发明涉及食品技术领域，更具体涉及一种具有辅助降血脂功效的泡腾片饮料。
背景技术
高血脂的魔爪已经渐渐地深入人们的生活，它不再是老年人身上才常见的疾病，人们生活压力越来越大，生活节奏也在不断的加快，不少年轻的朋友也是逐渐患上这种疾病。过量的饮酒、吸烟、缺乏运动，食用不易代谢的食物都是引起高血脂的因素。大量研究资料表明，高血脂症是脑卒中、冠心病、心肌梗死、猝死的危险因素。此外，高血脂症也是促进高血压、糖耐量异常、糖尿病的一个重要危险因素。高血脂症还可导致脂肪肝、肝硬化、胆石症、胰腺炎、眼底出血、失明、周围血管疾病、跛行、高尿酸血症。据调查全国30岁以上的成年人中间，高血脂症的发病率在10％-20％左右，高血脂症患者人数高达9000万。今年来平均每3个死亡的中国人中间就有一个死于心脑血管疾病，而高血脂症导致动脉粥样硬化是心脑血管疾病的罪魁祸首；大量医学研究表明：高血脂的治疗方法不能仅仅通过药物层面上，还要留意在日常生活中身体的调养。因此，开发出在日常生活中具有降血脂功效的保健产品具有广阔的市场前景。
大蒜又称葫蒜，葫，大豆蒜，为百合科植物大蒜的鳞茎。大蒜性味温辛，具有下气，消谷，除风，破冷，解毒，散痈等功效，大蒜油能降低血脂，对预防和治疗心血管病是有益的。然而由于大蒜可刺激胃粘膜，使胃酸增多，所以晚上睡不好的人(尤其更年期的障碍明显的妇女，大手术后或大量失血的人)以及目、口、齿、喉、舌诸热病者、胃溃疡及十二指肠溃疡病或慢性胃炎的人并不适合食用，加之大蒜具有的特殊气味，导致其在保健领域的应用受限。
发明内容
为了克服现有技术的不足，本发明提供一种具有辅助降血脂功效的泡腾片饮料，该泡腾片饮料采用可食用中药提取浸膏制备而成，营养丰富、口味独特、携带方便、易于溶解、冷溶热溶皆可，且生物利用度高、稳定性好，易于贮存，具有良好的辅助降血脂功效。
本发明通过以下技术方案来实现：
本发明提供一种具有辅助降血脂功效的泡腾片饮料，所述泡腾片饮料包括以下重量份的原料：可食用中药浸膏3～15份、崩解剂43～65份、润滑剂1～13份、填充剂2～10份、粘合剂1～8份、矫味剂0.5～3份、防腐剂0.5～2份，所述可食用中药浸膏为8～35份大蒜、6～30份沙棘、6～30份芦荟、3～20份荷叶、1～15份决明子的混合提取物。
血脂主要包括胆固醇(或称总胆固醇TC)和甘油三酯，在血循环中以非游离状态存在，和蛋白结合成脂蛋白这样的大分子运输。主要的脂蛋白分类---乳糜微粒、极低密度(前-β)脂蛋白(VLDL)、低密度(β-)脂蛋白(LDL)和高密度(a-)脂蛋白(HDL)---这些蛋白是紧密相联的，高脂血症由VLDL产生过多或清除障碍以及VLDL转变成LDL过多所致，当食物中的胆固醇(乳糜微粒的残余部分)到达肝脏时，引起细胞内的胆固醇(或肝细胞的胆固醇代谢产物)升高抑制了LDL-受体合成，亦抑制了LDL基因的转录，受体数量的下降引起血浆LDL和TC水平增高。所以降低或清除体内的胆固醇可以达到降低血脂的目的。本发明泡腾片饮料所含中药浸膏以大蒜降低胆固醇、保护心血管，以沙棘、芦荟辅助降低血液中的胆固醇、甘油三酯，同时软化血管、挥复血管弹性、降低血液粘度、改善微循环，佐以荷叶、山楂清除胆固醇、促进胆固醇的排泄，同时扩张血管，促进代谢，以决明子抑制胆固醇的吸收；方中六者合用，不仅可去除大蒜的特殊气味、降低大蒜的刺激性，还可从降脂、促排脂、抑脂、保护血管、恢复血管弹性、增强血液供血供氧能力等多方面结合，提高其降血脂的作用。
进一步地，上述可食用中药浸膏由以下重量份原料制备而成：大蒜12～30份、沙棘10～25份、芦荟10～25份、荷叶7～15份、山楂7～15份、决明子5～12份。
进一步地，所述可食用中药浸膏由大蒜、沙棘、芦荟、荷叶、山楂、决明子粉碎后溶于固液比为1g:(15～50)ml90％～95％乙醇中，于70℃下恒温水浴1～3小时，再于功率为240～800W、装载量为10～30ml条件下微波10～50s后真空浓缩干燥制得。
本发明中药浸膏的有效成分受提取提取时间、溶剂料液比等参数影响显著，通过本发明人大量研究发现本发明中药浸膏在该提取方法及提取参数下有效成分溶出及保留率相对较高、杂质少。装载量影响微波效率，从而影响该中药浸膏有效成分的萃取率，在该提取条件下该中药浸膏有效成分保留率和纯度较为理想。
进一步地，所述大蒜、沙棘、芦荟、荷叶、山楂、决明子粉碎粒度为2000～5000目。中药粉碎并不是越细越好，通过本发明人大量研究发现本发明中药粉碎粒度控制在2000～5000目范围内，既利于其有效成分的提取，又不会改变其成分。
进一步地，所述可食用中药浸膏由大蒜、沙棘、芦荟、荷叶、山楂、决明子粉碎后溶于固液比为1g:35ml90％～95％乙醇中，于70℃下恒温水浴2小时，再于功率为640W、装载量为25ml条件下微波30s后真空浓缩干燥制得。
进一步地，所述可食用中药浸膏在50℃时的相对密度为1.03～1.16g/L。在该密度范围内，本发明中药浸膏制备成泡腾片时较为稳定，更利于泡腾片的贮存。
进一步地，所述酸源为柠檬酸、酒石酸、富马酸、己二酸、苹果酸、水溶性氨基酸中的一种或几种混合；所述碱源为碳酸钠、碳酸氢钠、碳酸钾、碳酸氢钾、碳酸钙中的一种或几种混合。
进一步地，所述润滑剂为聚乙二醇4000、聚乙二醇6000、L-亮氨酸、苯甲酸钠、氯化钠中的一种或几种混合。
进一步地，所述矫味剂为薄荷油、薄荷醇、人造香草、香蕉味、柠檬味、橘味、苹果味中的一种或几种。
进一步地，所述防腐剂为苯甲酸钠、山梨酸钾、脱氢乙酸钠、丙酸钙中的一种或两种。
本发明具有辅助降血脂功效的泡腾片饮料具有如下的有益效果：
1、所含可食用中药浸膏有效成分溶出及保留率相对较高、杂质少；
2、本发明泡腾片饮料营养丰富、口味独特、携带方便、易于溶解、冷溶热溶皆可；
3、本发明泡腾片饮料安全、生物利用度高、稳定性好，易于贮存；
4、本发明泡腾片饮料可有效去除大蒜的特殊气味，同时降低大蒜的刺激性。
5、本发明泡腾片饮料可从降脂、促排脂、抑脂、保护血管、恢复血管弹性、增强血液供血供氧能力等多方面结合，提高其降血脂的作用。
具体实施方式
为了使本技术领域的人员更好地理解本发明的技术方案，下面结合实施例对本发明的技术方案作进一步详细的说明。
实施例1
本发明泡腾片饮料的配方：
可食用中药浸膏3份、柠檬酸18份、碳酸氢钠25份、聚乙二醇60002份、氯化钠1份、淀粉1份、乳糖1份、聚乙烯吡咯烷酮乙醇(水)溶液1份、乙醇溶液1份、苹果味矫味剂0.5份、苯甲酸钠0.7份；其中可食用中药浸膏由大蒜8份、沙棘6份、芦荟6份、荷叶3份、山楂3份、决明子1份混合粉碎(粉碎粒度为2000目)后溶于固液比为1g:15ml90％乙醇中，于70℃下恒温水浴1小时，再于功率为240W、装载量为10ml条件下微波10s后真空浓缩干燥至相对密度为1.03g/L(50℃)既得。
实施例2
可食用中药浸膏5份、柠檬酸21份、碳酸氢钠29份、碳酸钠3份、聚乙二醇60004份、氯化钠2份、甘露醇2份、乳糖2份、聚乙烯吡咯烷酮乙醇(水)溶液3份、橘味矫味剂1份、山梨酸钾0.9份；其中可食用中药浸膏由大蒜12份、沙棘10份、芦荟10份、荷叶7份、山楂7份、决明子5份混合粉碎(粉碎粒度为3000目)后溶于固液比为1g:25ml92％乙醇中，于70℃下恒温水浴1.5小时，再于功率为400W、装载量为15ml条件下微波20s后真空浓缩干燥至相对密度为1.06g/L(50℃)既得。
实施例3
可食用中药浸膏9份、苹果酸23份、碳酸氢钠31份、L-亮氨酸7份、葡萄糖6份、聚乙烯吡咯烷酮乙醇(水)溶液3份、乙醇溶液1份、苹果味矫味剂1.5份、脱氢乙酸钠1.3份；其中可食用中药浸膏由大蒜22份、沙棘18份、芦荟18份、荷叶11份、山楂11份、决明子8份混合粉碎(粉碎粒度为4000目)后溶于固液比为1g:35ml93％乙醇中，于70℃下恒温水浴2小时，再于功率为640W、装载量为20ml条件下微波30s后真空浓缩干燥至相对密度为1.09g/L(50℃)既得。
实施例4
可食用中药浸膏12份、富马酸24份、碳酸氢钠30份、苯甲酸钠10份、乳糖8份、聚乙烯吡咯烷酮乙醇(水)溶液4份、乙醇溶液2份、柠檬味矫味剂2.2份、苯甲酸钠1.7份；其中可食用中药浸膏由大蒜30份、沙棘25份、芦荟25份、荷叶15份、山楂15份、决明子12份混合粉碎(粉碎粒度为5000目)后溶于固液比为1g:45ml94％乙醇中，于70℃下恒温水浴2.5小时，再于功率为640W、装载量为25ml条件下微波40s后真空浓缩干燥至相对密度为1.12g/L(50℃)既得。
实施例5
可食用中药浸膏15份、柠檬酸28份、碳酸氢钠37份、聚乙二醇60009份、氯化钠4份、甘露醇6份、乳糖4份、聚乙烯吡咯烷酮乙醇(水)溶液5份、乙醇溶液3份、香蕉味矫味剂3份、苯甲酸钠2份；其中可食用中药浸膏由大蒜35份、沙棘30份、芦荟30份、荷叶20份、山楂20份、决明子15份混合粉碎后溶于固液比为1g:50ml95％乙醇中，于70℃下恒温水浴3小时，再于功率为800W、装载量为30ml条件下微波50s后真空浓缩干燥至相对密度为1.16g/L(50℃)既得。
以上所述实施例仅表达了本发明的几种实施方式，其描述较为具体和详细，但并不能因此而理解为对本发明专利范围的限制。应当指出的是，对于本领域的普通技术人员来说，在不脱离本发明构思的前提下，还可以做出若干变形和改进，这些都属于本发明的保护范围。因此，本发明专利的保护范围应以所附权利要求为准。
Claims (10)
1.一种具有辅助降血脂功效的泡腾片饮料，其特征在于，所述泡腾片饮料包括以下重量份的原料：
可食用中药浸膏3～15份、崩解剂43～65份、润滑剂1～13份、填充剂2～10份、粘合剂1～8份、矫味剂0.5～3份、防腐剂0.5～2份，所述可食用中药浸膏为8～35份大蒜、6～30份沙棘、6～30份芦荟、3～20份荷叶、1～15份决明子的混合提取物。
2.根据权利要求1所述的具有辅助降血脂功效的泡腾片饮料，其特征在于，所述可食用中药浸膏由以下重量份原料制备而成：
大蒜12～30份、沙棘10～25份、芦荟10～25份、荷叶7～15份、山楂7～15份、决明子5～12份。
3.根据权利要求1或2所述的具有辅助降血脂功效的泡腾片饮料，其特征在于，所述可食用中药浸膏由大蒜、沙棘、芦荟、荷叶、山楂、决明子粉碎后溶于固液比为1g:(15～50)ml90％～95％乙醇中，于70℃下恒温水浴1～3小时，再于功率为240～800W、装载量为10～30ml条件下微波10～50s后真空浓缩干燥制得。
4.根据权利要求3所述的具有辅助降血脂功效的泡腾片饮料，其特征在于，所述大蒜、沙棘、芦荟、荷叶、山楂、决明子粉碎粒度为2000～5000目。
5.根据权利要求1或2所述的具有辅助降血脂功效的泡腾片饮料，其特征在于，所述可食用中药浸膏由大蒜、沙棘、芦荟、荷叶、山楂、决明子粉碎后溶于固液比为1g:35ml90％～95％乙醇中，于70℃下恒温水浴2小时，再于功率为640W、装载量为25ml条件下微波30s后真空浓缩干燥制得。
6.根据权利要求1或2所述的具有辅助降血脂功效的泡腾片饮料，其特征在于，所述可食用中药浸膏在50℃时的相对密度为1.03～1.16g/L。
7.根据权利要求1所述的具有辅助降血脂功效的泡腾片饮料，其特征在于，所述崩解剂包括一个酸源和一个碱源，所述酸源为柠檬酸、酒石酸、富马酸、己二酸、苹果酸、水溶性氨基酸中的一种或几种混合；所述碱源为碳酸钠、碳酸氢钠、碳酸钾、碳酸氢钾、碳酸钙中的一种或几种混合。
8.根据权利要求1所述的具有辅助降血脂功效的泡腾片饮料，其特征在于，所述润滑剂为聚乙二醇4000、聚乙二醇6000、L-亮氨酸、苯甲酸钠、氯化钠中的一种或几种混合。
9.根据权利要求1所述的具有辅助降血脂功效的泡腾片饮料，其特征在于，所述矫味剂为薄荷油、薄荷醇、人造香草、香蕉味、柠檬味、橘味、苹果味中的一种或几种。
10.根据权利要求1所述的具有辅助降血脂功效的泡腾片饮料，其特征在于，所述防腐剂为苯甲酸钠、山梨酸钾、脱氢乙酸钠、丙酸钙中的一种或两种。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610289380.4A CN105901464A (zh) | 2016-05-04 | 2016-05-04 | 一种具有辅助降血脂功效的泡腾片饮料 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610289380.4A CN105901464A (zh) | 2016-05-04 | 2016-05-04 | 一种具有辅助降血脂功效的泡腾片饮料 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105901464A true CN105901464A (zh) | 2016-08-31 |
Family
ID=56753371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610289380.4A Pending CN105901464A (zh) | 2016-05-04 | 2016-05-04 | 一种具有辅助降血脂功效的泡腾片饮料 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105901464A (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107223842A (zh) * | 2017-06-22 | 2017-10-03 | 鄢心怡 | 荷叶清凉泡腾颗粒 |
| CN109717271A (zh) * | 2017-10-27 | 2019-05-07 | 上海寿叶生物科技有限公司 | 一种荷润茶植物代用茶及制作工艺 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1745809A (zh) * | 2004-09-08 | 2006-03-15 | 徐燕和 | 六味地黄泡腾片及其制备方法 |
| CN101695324A (zh) * | 2009-09-21 | 2010-04-21 | 杭州六易科技有限公司 | 一种调节血脂的降脂茶的制作方法 |
| CN105462938A (zh) * | 2014-08-06 | 2016-04-06 | 天津贾立明蚯蚓养殖有限公司 | 一种杞龙sod营养口服液的加工工艺及配方 |
-
2016
- 2016-05-04 CN CN201610289380.4A patent/CN105901464A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1745809A (zh) * | 2004-09-08 | 2006-03-15 | 徐燕和 | 六味地黄泡腾片及其制备方法 |
| CN101695324A (zh) * | 2009-09-21 | 2010-04-21 | 杭州六易科技有限公司 | 一种调节血脂的降脂茶的制作方法 |
| CN105462938A (zh) * | 2014-08-06 | 2016-04-06 | 天津贾立明蚯蚓养殖有限公司 | 一种杞龙sod营养口服液的加工工艺及配方 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107223842A (zh) * | 2017-06-22 | 2017-10-03 | 鄢心怡 | 荷叶清凉泡腾颗粒 |
| CN109717271A (zh) * | 2017-10-27 | 2019-05-07 | 上海寿叶生物科技有限公司 | 一种荷润茶植物代用茶及制作工艺 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100421567C (zh) | 一种速溶普洱茶及其制备方法 | |
| TWI293021B (en) | Weight management beverage | |
| CN101862367B (zh) | 一种降脂减肥用决明子软胶囊及其制备方法 | |
| CN104054769B (zh) | 一种治疗心血管疾病的功能面包及其制作方法 | |
| CN104287036B (zh) | 一种中草药绿茶保健醋饮料及生产工艺 | |
| CN104383156B (zh) | 一种具有减肥和降血脂功效的组合物及其制备方法与用途 | |
| CN105876589A (zh) | 一种具有调节免疫力功效的泡腾片饮料 | |
| JP2016532446A (ja) | 円武扇発酵物含有食品または飲料組成物 | |
| KR101488612B1 (ko) | 흑색 식품소재를 함유하는 건강식품 및 약학적 조성물 | |
| CN107083311A (zh) | 壳寡糖健康养生酒及其制备方法 | |
| CN101543295B (zh) | 一种降压降脂保健茶 | |
| CN1215861C (zh) | 夏桑菊泡腾片及其制备工艺 | |
| CN102687781B (zh) | 苦荞茶泡腾片及其制备方法 | |
| CN105901464A (zh) | 一种具有辅助降血脂功效的泡腾片饮料 | |
| JP4812222B2 (ja) | ミネラル吸収促進剤 | |
| CN106999532A (zh) | 含有复合提取物的运动执行能力增强及体力增进用组合物 | |
| CN104522244A (zh) | 无糖罗汉果饮料及其生产方法 | |
| CN104186657B (zh) | 一种白术奶醋绿茶保健饮料 | |
| CN101884408A (zh) | 一种银杏叶浸提液及其制备方法 | |
| CN105961994A (zh) | 一种具有减肥瘦身功效的泡腾片饮料 | |
| CN104997018A (zh) | 一种红豆杉酵素保健品及其制备方法和应用 | |
| CN104474337B (zh) | 一种含绿茶提取物的中成保健冲剂的制备方法 | |
| CN107384680A (zh) | 一种百香果龙眼果酒及其酿造方法 | |
| CN105961992A (zh) | 一种具有改善睡眠功效的泡腾片饮料 | |
| CN102422887A (zh) | 绞股蓝膏汁姜奶茶 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information | ||
| CB02 | Change of applicant information |
Address after: Nansha District Fengze road Guangzhou city Guangdong province 511458 No. 106 X1301-B437 Applicant after: Guangzhou poly injection General Technology Research Institute Co Ltd Address before: Nansha District Fengze road Guangzhou city Guangdong province 511458 No. 106 X1301-B437 Applicant before: GUANGZHOU JUZHU PATENT RESEARCH AND DEVELOPMENT CO., LTD. |
|
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160831 |