CN105726361A - Skin-moisturizing essential oil and preparation method thereof - Google Patents

Skin-moisturizing essential oil and preparation method thereof Download PDF

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Publication number
CN105726361A
CN105726361A CN201610101836.XA CN201610101836A CN105726361A CN 105726361 A CN105726361 A CN 105726361A CN 201610101836 A CN201610101836 A CN 201610101836A CN 105726361 A CN105726361 A CN 105726361A
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oil
skin
moisturizing
quintessence oil
essential oil
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杨少凡
胡林刚
马创伟
刘锦
杨晶晶
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GUANGXI WANSHAN PERFUME CO Ltd
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GUANGXI WANSHAN PERFUME CO Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00Essential oils; Perfumes
    • C11B9/0003Compounds of unspecified constitution defined by the chemical reaction for their preparation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

The invention provides skin-moisturizing essential oil and a preparation method thereof. The skin-moisturizing essential oil is prepared from, by weight, 90-100 parts of jojoba oil, 0.5-4 parts of sweet almond oil, 0.5-2 parts of aloe oil, 0.1-1 part of sweet orange essential oil, 0.1-0.5 part of lavender essential oil and 0.01-0.05 part of rose essential oil. The preparation method comprises the steps that the sweet almond oil, the aloe oil, the sweet orange essential oil, the lavender essential oil and the rose essential oil are put into a vessel, uniform stirring is conducted in the same direction, the jojoba oil is added, stirring is conducted in the same direction, and the skin-moisturizing essential oil is obtained. The skin-moisturizing essential oil can promote fibrocyte proliferation and effectively remove free radicals, and therefore the anti-wrinkle effect is greatly improved.

Description

A kind of skin-moisturizing, skin quintessence oil and preparation method thereof
Technical field
The present invention relates to a kind of plants essential oil and preparation method thereof, be specifically related to a kind of skin-moisturizing, skin quintessence oil and preparation method thereof.
Background technology
Skin aging is the modal aging phenomenon of human body, is divided into natural aging and two kinds of forms of photoaging, and natural aging refers to owing in heredity and body, irresistible factor causes, and sees exposure and non-exposed position, hence it is evident that be characterized as appearance and the cutis laxa of wrinkle;Photoaging is then caused by the extrinsic factor such as environmental factors such as ultraviolet, smoking, wind, contact chemical substance.Photoaging shows as that exposure portion is coarse, wrinkle overstriking intensification, organizational structure exception, the deformation of scrambling pigmentation, corium elastic fiber and catabolite accumulation etc..But causing that the most the underlying cause of aging is under internal and external factor effect, cell viability declines, synthesis and metabolic capacity decline, cause that the conversion multiplication capacity of epidermis cell and the ability of fibroblastic synthetic fibers albumen and elastin fiber decline.But the crease-resistant mechanism of existing crease-resistant skin care item is single, anti-wrinkle effect is not good.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of skin-moisturizing, skin quintessence oil and preparation method thereof, and this skin-moisturizing, skin quintessence oil is possible not only to promote fibroblast proliferation, it is also possible to effectively scavenging free radicals, thus substantially increasing anti-wrinkle effect.
Technical scheme provided by the invention is a kind of skin-moisturizing, skin quintessence oil, including the raw material of following weight portion: Jojoba oil 90~100 parts, Semen pruni armeniacae oil 0.5~4 part, aloe 0.5~2 part, sweet orange oil 0.1~1 part, Herba Lysimachiae foenum-graeci quintessence oil 0.1~0.5 part and Flos Rosae Rugosae quintessence oil 0.01~0.05 part.
In above-mentioned formula:
Jojoba oil is the base oil that permeability is the strongest, is very easily absorbed by the skin, and clearly moistens, non-greasy, wrinkle removing stricture of vagina, can be effectively improved oily skin, nurses one's health smegma function, pore refining, is also best skin moisture-keeping oil simultaneously.The oil film that it is formed is different from mineral oil, can pass through the moisture of evaporation, also can control the loss of moisture.
Semen pruni armeniacae oil rich in mineral substances, protein and various vitamin, be a kind of skin care and the splendid vegetable oil of moisturizing effect, can effectively facilitate fibroblastic growth and the effect of synthesis collagen.
Pure oiliness Aloe gel contained by aloe, by nature moisturizing factor such as supplementary mucopolysaccharides, makes skin recover elasticity, aufhellung microgroove.
Containing substantial amounts of VC in sweet orange oil, the conversion multiplication capacity that can promote epidermis cell and the ability collagen protein being enhanced to fibrocellular rubber polymer fibrillin and elastin fiber are formed, also there is splendid antioxygenic property, the scavenging free radicals injury to skin simultaneously.
Herba Lysimachiae foenum-graeci quintessence oil is to be refined by lavandula angustifolia to form, and quickly penetrates into hair follicle disinfecting, antimicrobial, promotes cell regeneration, stimulate fibroblastic formation, recovers skin connective tissue and antioxygenic property.
Flos Rosae Rugosae quintessence oil, can promote that cell metabolism is with cell regeneration function, fibroblast is stimulated to divide and synthesize collagen, also there is the effect eliminating free radical simultaneously, improve skin moisturizing ability, keeping elastic fibers and collagen to put in order constant, maintaining mechanical force and the elasticity of skin, thus avoiding the formation of wrinkle.
Above-mentioned quintessence oil can pass through steam distillation, squeezing and pressing method, cold-maceration or solvent extraction method and refine the volatility direction material extracted.These quintessence oils can be commercially available respectively, it is possible to extracts preparation voluntarily according to the method for prior art.Each quintessence oil in the present invention should meet associated treatment standard-required.
As preferably, the weight portion of each raw material is: Jojoba oil 95~100 parts, Semen pruni armeniacae oil 0.5~1 part, aloe 0.5~1 part, sweet orange oil 0.1~0.5 part, Herba Lysimachiae foenum-graeci quintessence oil 0.1~0.2 part and Flos Rosae Rugosae quintessence oil 0.04~0.05 part.
It is further preferred that the weight portion of each raw material is: Jojoba oil 98.205 parts, Semen pruni armeniacae oil 0.8 part, aloe 0.6 part, sweet orange oil 0.2 part, Herba Lysimachiae foenum-graeci quintessence oil 0.15 part and Flos Rosae Rugosae quintessence oil 0.045 part.
The preparation method that present invention also offers above-mentioned skin-moisturizing, skin quintessence oil, the Semen pruni armeniacae oil of formula ratio, aloe, sweet orange oil, Herba Lysimachiae foenum-graeci quintessence oil and Flos Rosae Rugosae quintessence oil are put in vessel, stirs to same direction, add Jojoba oil, same direction is stirred, and to obtain final product.
Compared with prior art, the method have the advantages that
1) the skin-moisturizing, skin quintessence oil of the present invention is by composite for various plants quintessence oil, make composite essential oil both can strengthen cell proliferation, metabolic capacity, to promote the conversion multiplication capacity of epidermis cell and to be enhanced to the ability of fibrocellular rubber polymer fibrillin and elastin fiber, all right scavenging free radicals, to eliminate the infringement of free radical degree skin, thus substantially increasing the moisture-keeping crease-shedding effect of composite essential oil.These 6 kinds of quintessence oils are worked in coordination with mutually, create the cooperative effect of 1+1 > 2.
2) the skin-moisturizing, skin quintessence oil of the present invention can also pass through to supplement the nature moisturizing factor such as mucopolysaccharide, reconstituted cell epimatrix, makes skin recover elasticity, thus aufhellung wrinkle.
Detailed description of the invention
The present invention is further elaborated for specific examples below, but not as a limitation of the invention.
Embodiment 1
Formula: Jojoba oil 90g, Semen pruni armeniacae oil 0.5g, aloe 0.5g, sweet orange oil 0.1g, Herba Lysimachiae foenum-graeci quintessence oil 0.1g and Flos Rosae Rugosae quintessence oil 0.01g.
Preparation method:
Putting in vessel by the Semen pruni armeniacae oil of formula ratio, aloe, sweet orange oil, Herba Lysimachiae foenum-graeci quintessence oil and Flos Rosae Rugosae quintessence oil, stir to same direction, add Jojoba oil, same direction is stirred, and to obtain final product.
Embodiment 2
Formula: Jojoba oil 95g, Semen pruni armeniacae oil 0.5g, aloe 0.5g, sweet orange oil 0.1g, Herba Lysimachiae foenum-graeci quintessence oil 0.1g and Flos Rosae Rugosae quintessence oil 0.04g.
Preparation method:
Putting in vessel by the Semen pruni armeniacae oil of formula ratio, aloe, sweet orange oil, Herba Lysimachiae foenum-graeci quintessence oil and Flos Rosae Rugosae quintessence oil, stir to same direction, add Jojoba oil, same direction is stirred, and to obtain final product.
Embodiment 3
Formula: Jojoba oil 98.205g, Semen pruni armeniacae oil 0.8g, aloe 0.6g, sweet orange oil 0.2g, Herba Lysimachiae foenum-graeci quintessence oil 0.15g and Flos Rosae Rugosae quintessence oil 0.045g.
Preparation method:
Putting in vessel by the Semen pruni armeniacae oil of formula ratio, aloe, sweet orange oil, Herba Lysimachiae foenum-graeci quintessence oil and Flos Rosae Rugosae quintessence oil, stir to same direction, add Jojoba oil, same direction is stirred, and to obtain final product.
Embodiment 4
Formula: Jojoba oil 100g, Semen pruni armeniacae oil 4g, aloe 2g, sweet orange oil 1g, Herba Lysimachiae foenum-graeci quintessence oil 0.5g and Flos Rosae Rugosae quintessence oil 0.05g.
Preparation method:
Putting in vessel by the Semen pruni armeniacae oil of formula ratio, aloe, sweet orange oil, Herba Lysimachiae foenum-graeci quintessence oil and Flos Rosae Rugosae quintessence oil, stir to same direction, add Jojoba oil, same direction is stirred, and to obtain final product.
Experimental example
1, skin-moisturizing, skin quintessence oil oxidation resistance test
1) removing to DPPH
Weighing the skin-moisturizing, skin quintessence oil 0.5g of embodiment 1~4, with proceeding to constant volume in 100ml volumetric flask after pure water ultrasonic disperse, preparation mass concentration is that 5mg/ml solution as the sample solution of experimental group 1~4 and measures its non-oxidizability.And weigh Estee Lauder instant maintenance eye essence frost (being commonly called as little palm fibre bottle, be purchased from store, Jingdone district) 0.5g, with proceeding to constant volume in 100ml volumetric flask after pure water pure water ultrasonic disperse, preparation mass concentration is 5mg/ml solution sample solution as a control group.
Take 2.00 × 10 respectively-4Mol/LDPPH ethanol solution and the above-mentioned each group of each 3ml of sample solution add in same tool plug test tube, shake up, and lucifuge measures the mixed solution absorbance A at 517nm place with ultraviolet-visible spectrophotometer after preventing 30mini1, measure pure water and the mixed absorbance A of 3mlDPPH ethanol solution of 3ml simultaneously01And 3ml sample solution and the mixed absorbance A of 3ml dehydrated alcoholj1, calculate clearance rate P according to formula1, result is in Table 1.
P1=[1-(Ai1-Aj1)/A01] × 100%.
2) clearance rate to OH
Take 2ml1.00 × 10-2Salicylic acid-the alcoholic solution of mol/L, 2ml9.00 × 10-3The FeSO of mol/L4Solution and the above-mentioned each group of sample solution of 2ml add in same tool plug test tube, are subsequently adding 2ml8.8 × 10-2The H of mol/L2O2Solution, is positioned in 37 DEG C of water-baths and reacts 30min after shaking up, measure absorbance A at 510nm placei2, replace salicylic acid solution to measure absorbance A with 2ml pure waterj2, replace sample solution to measure absorbance A with 2ml pure water02.Clearance rate P is calculated according to formula2, result is in Table 1.
P2=[1-(Ai2-Aj2)/A02] × 100%.
3) to O2 -Clearance rate
Take the Tris-HCl buffer solution 5ml that pH is 8.2 and fill in test tube in tool, after preheating 20min in 25 DEG C of water-baths, be sequentially added into above-mentioned each group of sample solution 2ml and 5.00 × 10-3Mol/L pyrogallol solution 0.5ml is (with 1.00 × 10-2The HCl solution preparation of mol/L), shake up reaction 4min in 25 DEG C of water-baths immediately, measure its absorbance A immediately at 320nm placei3, with 1.00 × 10-2The HCl solution 0.5ml of mol/L replaces pyrogallol measured in solution absorbance Aj3, replace sample solution to measure absorbance A with 2ml pure water solution03.Clearance rate P is calculated according to formula3, result is in Table 1.
P3=[1-(Ai3-Aj3)/A03] × 100%.
Table 1 skin-moisturizing, skin quintessence oil oxidation resistance test result
Group DPPH clearance rate OH clearance rate ·O2 -Clearance rate
Experimental group 1 88.9 64.1 58.9
Experimental group 2 86.7 65.2 60.0
Experimental group 3 92.1 75.4 68.7
Experimental group 4 85.6 68.3 61.4
Matched group 74.3 54.2 44.7
2, the skin-moisturizing, skin quintessence oil impact on proliferative activity of fibroblasts
Weighing the skin-moisturizing, skin quintessence oil 0.5g of embodiment 1~4, with proceeding to constant volume in 100ml volumetric flask after pure water ultrasonic disperse, preparation mass concentration is the 5mg/ml solution sample solution as experimental group 1~4.And weigh Estee Lauder instant maintenance eye essence frost (being commonly called as little palm fibre bottle, be purchased from store, Jingdone district) 0.5g, with proceeding to constant volume in 100ml volumetric flask after pure water pure water ultrasonic disperse, preparation mass concentration is 5mg/ml solution sample solution as a control group.
Taking the foreskin specimen of Wrapping annulus cuts operation patient, conventional method cultivates human fibroblasts, takes the 5th generation purification fibroblast, it is seeded to 96 orifice plates with 3000/hole, after band cell attachment, discards culture fluid, changing the sample solution 100ul of above-mentioned each group into, often group sets 6 multiple holes.Respectively with change 72h, 96h and 120h after liquid and add 10ulWST-8 solution, hatch after 3h by microplate reader in 450nm place reading absorbance.Result is in Table 2.
The impact on proliferative activity of fibroblasts of the table 2 skin-moisturizing, skin quintessence oil
3, the skin-moisturizing, skin quintessence oil impact on skin moisture content
Choosing 20~35 years old tested volunteer of women 300, wherein less than 25 years old 100, as First Year age group;25~30 years old 100, as Second Year age group;30~35 years old 100, as the 3rd age group.Choose two regions that the tested volunteer face of First Year age group is symmetrical, test zone respectively as experimental group 1 and matched group 1, Second Year age group and the 3rd age group are by that analogy, it is divided into experimental group 2 and matched group 2 and experimental group 3 and matched group 3, in dehumidifier environment (temperature 20 DEG C, humidity 50%) testing moisture content.Cleaning skin of face, experimenter sits quietly after 30min in constant environment, uses skinanalysis apparatus (Germany CKCutometerMPA580) to carry out the measurement of recipient site blank value.Divide according to the facial zone of experimental group and matched group, smear skin-moisturizing, skin quintessence oil and the Estee Lauder instant maintenance eye essence frost (being commonly called as little palm fibre bottle, be purchased from store, Jingdone district) of the embodiment 3 of equivalent respectively at cheek antimere.The moisture in two regions of test, interval time is 30min, 1h, 2h, 3h, 4h, 12h respectively.Recording three groups of experimenters skin moisture content in experimental group and matched group region, record each experimental data, result is in Table 1.Computing formula is: moisture content of skin rate of increase=(MMVt-MMV0)/MMV0) × 100%
In formula, MMVtFor smearing the skin MMV (humidity measurements) of rear t period;
MMV0For smearing front skin MMV;
Adopting the test of capacitance method principle, be pressed in moisture measurement probe vertical by side skin surface, probe top is pushed back a segment distance, and probe is internal has a spring to make probe top keep the pressure of 0.16N to be pressed in skin surface, shows result in one second on main frame.
The impact on skin moisture content rate of increase of the table 1 skin-moisturizing, skin quintessence oil
4, the skin-moisturizing, skin quintessence oil impact on skin elasticity
Choosing 20~35 years old tested volunteer of women 300, wherein less than 25 years old 100, as First Year age group;25~30 years old 100, as Second Year age group;30~35 years old 100, as the 3rd age group.Choose two regions that the tested volunteer face of First Year age group is symmetrical, test zone respectively as experimental group 1 and matched group 1, Second Year age group and the 3rd age group are by that analogy, it is divided into experimental group 2 and matched group 2 and experimental group 3 and matched group 3, skin elasticity is tested in dehumidifier environment (temperature 20 DEG C, humidity 50%).Experimental group smears the heal-care essential oil of embodiment 3 every day sooner or later, and matched group Estee Lauder instant maintenance eye essence frost (is commonly called as little palm fibre bottle, be purchased from store, Jingdone district).Test under the same conditions for two groups.
Cleaning skin of face, experimenter sits quietly after 30min in constant environment, uses skinanalysis apparatus (Germany CKCutometerMPA580) to carry out the measurement of recipient site blank value.Divide according to the facial zone of experimental group and matched group, the quintessence oil of equivalent is smeared and Estee Lauder instant maintenance eye essence frost (is commonly called as little palm fibre bottle respectively at cheek antimere, it is purchased from store, Jingdone district), the skin elasticity in two regions of test, test period is 30 days.The result of skin elasticity is represented by the elasticity measurement value (EMV) set, namely skin stretch amount, record three groups of experimenters skin elasticity at experimental group and matched group region, record the experimental data in whole cycle, and calculate skin elasticity increment rate.Formula is: skin elasticity increment rate %=(EMVt-EMV0)/EMV0× 100%
In formula, EMV0For smearing front skin EMV;
EMVtFor smearing rear t period skin EMV.
Adopting suction and stretching principle to test, produce a constant negative pressure by one fc-specific test FC probe of skin inspiration being test for skin surface, the degree of depth that skin is sucked in test probe is to be recorded by a contactless optic testing system.The emitter and receiver of light is included in test probe, the ratio (launch light and accept the ratio of light) of light is directly proportional with the degree of depth being inhaled into skin, thus obtain the relation curve of length that a skin is stretched and practice, then pass through MPA software analysis to determine the elastic performance of skin.
As seen from the above table, the skin elasticity of experimental group and matched group all increases to some extent, but the elastic increment rate of experimental group is apparently higher than matched group.

Claims (4)

1. a skin-moisturizing, skin quintessence oil, it is characterised in that: include the raw material of following weight portion: Jojoba oil 90~100 parts, Semen pruni armeniacae oil 0.5~4 part, aloe 0.5~2 part, sweet orange oil 0.1~1 part, Herba Lysimachiae foenum-graeci quintessence oil 0.1~0.5 part and Flos Rosae Rugosae quintessence oil 0.01~0.05 part.
2. skin-moisturizing, skin quintessence oil according to claim 1, it is characterised in that: the weight portion of each raw material is: Jojoba oil 95~100 parts, Semen pruni armeniacae oil 0.5~1 part, aloe 0.5~1 part, sweet orange oil 0.1~0.5 part, Herba Lysimachiae foenum-graeci quintessence oil 0.1~0.2 part and Flos Rosae Rugosae quintessence oil 0.04~0.05 part.
3. skin-moisturizing, skin quintessence oil according to claim 1, it is characterised in that: the weight portion of each raw material is: Jojoba oil 98.205 parts, Semen pruni armeniacae oil 0.8 part, aloe 0.6 part, sweet orange oil 0.2 part, Herba Lysimachiae foenum-graeci quintessence oil 0.15 part and Flos Rosae Rugosae quintessence oil 0.045 part.
4. the preparation method of the skin-moisturizing, skin quintessence oil according to any one of claims 1 to 3, it is characterized in that: the Semen pruni armeniacae oil of formula ratio, aloe, sweet orange oil, Herba Lysimachiae foenum-graeci quintessence oil and Flos Rosae Rugosae quintessence oil are put in vessel, stir to same direction, add Jojoba oil, same direction is stirred, and to obtain final product.
CN201610101836.XA 2016-02-24 2016-02-24 Skin-moisturizing essential oil and preparation method thereof Pending CN105726361A (en)

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Cited By (6)

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Publication number Priority date Publication date Assignee Title
CN106491401A (en) * 2016-11-26 2017-03-15 无锡市汉方八珍科技有限公司 A kind of skin moistening quintessence oil and preparation method thereof
CN107557164A (en) * 2017-10-10 2018-01-09 广东长利香精香料有限公司 A kind of lemongrass sweet orange oil
CN108567631A (en) * 2017-10-19 2018-09-25 无锡市天爱装饰工程有限公司 A kind of self-control mulberry leaf eye mask
CN108852904A (en) * 2018-07-04 2018-11-23 范加家 A kind of mite killing moisturizing compound borneol essential oil and preparation method thereof
CN110772454A (en) * 2019-12-13 2020-02-11 湖北创界生物科技有限公司 Compound essential oil for skin brightening, moisturizing, soothing and anti-aging, and preparation method and application thereof
CN113101241A (en) * 2021-04-08 2021-07-13 广东丸美生物技术股份有限公司 Skin-care matrix and preparation method and application thereof

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106491401A (en) * 2016-11-26 2017-03-15 无锡市汉方八珍科技有限公司 A kind of skin moistening quintessence oil and preparation method thereof
CN107557164A (en) * 2017-10-10 2018-01-09 广东长利香精香料有限公司 A kind of lemongrass sweet orange oil
CN108567631A (en) * 2017-10-19 2018-09-25 无锡市天爱装饰工程有限公司 A kind of self-control mulberry leaf eye mask
CN108852904A (en) * 2018-07-04 2018-11-23 范加家 A kind of mite killing moisturizing compound borneol essential oil and preparation method thereof
CN110772454A (en) * 2019-12-13 2020-02-11 湖北创界生物科技有限公司 Compound essential oil for skin brightening, moisturizing, soothing and anti-aging, and preparation method and application thereof
CN110772454B (en) * 2019-12-13 2023-07-21 湖北创界生物科技有限公司 Skin-brightening, moisturizing, soothing and anti-aging compound essential oil, and preparation method and application thereof
CN113101241A (en) * 2021-04-08 2021-07-13 广东丸美生物技术股份有限公司 Skin-care matrix and preparation method and application thereof

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Application publication date: 20160706