CN105628687A - Full-automatic chemiluminiscence tester - Google Patents

Abstract

The invention discloses a full-automatic chemiluminiscence tester and belongs to the field of chemiluminiscence testing.The full-automatic chemiluminiscence tester comprises a mechanical arm module, a refrigeration module, a power module, a reagent sample disk, a sampling needle component, a stirring component, a reaction cup frame, an incubation device, a magnetic separation component, a washing station component and a measuring room.Full-automatic management is achieved for mixing, reacting, incubating, magnetic separating, detecting and other procedures of a sample to be tested, the detection efficiency is improved, and operation errors are reduced.

Description

A kind of Full-automatic chemiluminescence analyzer

Technical field

The present invention relates to chemical luminescent detecting field, particularly relate to a kind of Full-automatic chemiluminescence analyzer.

Background technology

Chemical luminescent detecting technology is high because of its accuracy, is used widely at biological medicine detection field. In detection process, according to different detection projects, it is necessary to censorship sample is added different reagent. Current testing process generally adopts manual operation or semi-automatic operation, and owing to the label on detection sample cup is carried out artificial cognition by staff, such manual operation flow process exists that detection speed is slow and the problem of inefficiency, there is security risk simultaneously. And semi-automatic analyzer can only realize the automatization of part, remain on needs and manual operation matches, cause that mensuration wastes time and energy, and data cannot be transmitted directly in computer, under experiment needs to require accurately, still inevitably cause error.

Summary of the invention

Problem to be solved: for problem above, the present invention provides a kind of Full-automatic chemiluminescence analyzer, by whole automated managements of program such as the mixing of testing sample, reaction, incubation, Magneto separate, detections, improves detection efficiency, reduces operational error.

For solving above technical problem, the present invention adopts the following technical scheme that

A kind of Full-automatic chemiluminescence analyzer, including mechanical arm module, refrigeration module, power module, reagent sample disk, sampling needle assembly, mixing component, reaction glass stand, incubation device, Magneto separate assembly, cleaning station assembly, measurement apparatus;

Described mechanical arm module for capturing reaction cup in three dimensions;

Described refrigeration module provides low temperature environment for reagent sample disk;

Described power module is analyzer running power supply;

Described reagent sample disk is used for placing sample tube and reagent bottle;

Sample liquid in reagent sample disk or reagent are injected in the reaction cup in incubation device by described sampling needle assembly;

Reaction cup in incubation device is stirred by described mixing component;

Described reaction glass stand is easy to mechanical arm module for placing response cup and is captured reaction cup;

Described incubation device provides isoperibol for reaction cup;

Reaction cup on incubation device is carried out Magneto separate by described Magneto separate assembly;

Reaction cup after Magneto separate is carried out by described cleaning station assembly;

Described measurement apparatus is to the reaction cup measurement after cleaning.

Further technical scheme, described mechanical arm module includes X-axis guide assembly, Y-axis guide assembly, Z axis guide assembly, X-axis motor, y-axis motor, Z axis motor, mechanical gripper and mechanical gripper motor, described X-axis guide assembly is connected with X-axis motor, described Y-axis guide assembly is connected with y-axis motor, described Z axis guide assembly is connected with Z axis motor, and described mechanical gripper is connected with mechanical gripper motor; Described Y-axis guide assembly is located on X-axis guide assembly, and described Z axis guide assembly is located on Y-axis guide assembly, and described mechanical gripper is located on Z axis guide assembly; Described mechanical gripper includes jaw, detecting device, and described detecting device is located at above jaw;

Described reagent sample disk includes evenly mixing device, thermal insulation cover, plexiglass cover, sample disk, reagent disc, sample disk support; Described sample disk is located on sample disk support, described evenly mixing device is positioned at the lower section of sample disk, described reagent disc is positioned at the inside of sample disk, described thermal insulation cover is located at the periphery of sample disk, described lucite is covered on thermal insulation cover and seals with thermal insulation cover and coordinates, the circumference outer ring of described sample disk is provided with sample pore, and the side of described thermal insulation cover is provided with refrigeration window, described refrigeration window and refrigeration module and seals cooperation;

Described incubation device includes incubation dish, conducting slip ring, rotary tray motor, heating plate, temperature sensor, incubation disc carrier, and described incubation dish is located on incubation disc carrier, and the back side of described incubation dish is provided with heating plate and temperature sensor; Described conducting slip ring is located at the wire of the center of incubation dish, heating plate and temperature sensor and is all wrapped on conducting slip ring; The axle that rotates of described rotary tray motor is connected with the center of incubation dish; The round edge of described incubation dish is provided with some reaction cup aperture;

Described Magneto separate assembly includes the motor that seesaws, promote device, magnet frame, Magnet, Magnet fixed block, Magneto separate support, Magneto separate base, spring assembly, described magnet frame is connected with the motor that seesaws by promoting device, magnet frame is provided with some magnetic receivers, described Magnet fixed block is located in magnetic receiver, described Magnet is located at the side simultaneously acting on reaction cup in Magnet fixed block close to bottom place, the described motor that seesaws, device and magnet frame is promoted all to be located on Magneto separate support, described Magneto separate props up and is set up on Magneto separate base, described spring assembly is located at inside magnetic receiver, and it is positioned at after Magnet fixed block,

Described measurement apparatus includes photomultiplier tube, renovate motor, renovate, measurement apparatus electric rotating machine, measuring chamber, strengthen liquid filler, described photomultiplier tube is connected with measuring chamber, described motor of renovating is connected with renovating by measurement apparatus connecting rod, it is provided with rotor inside described measuring chamber, rotor is provided with some reaction cup and places position, described rotor includes a primary response cup and places position and a detection reaction cup placement position, described primary response cup is placed position and is positioned at the underface of measuring chamber opening, described detection reaction cup is placed position and is positioned on the detecting position of measuring chamber, the described opening sealing cooperation with measuring chamber of renovating makes whole measuring chamber be internally formed sealing space, described measurement apparatus electric rotating machine is connected with rotor, described strengthens the top that liquid filler is arranged in the detecting position of measuring chamber.

Further technical scheme, described refrigeration module includes air scoop, upper clamshell, lower clamshell, semiconductor chilling plate, radiator fan, chilled air fan, cool guide sheet, bracer and fin; Described upper clamshell is connected with lower clamshell; Described cool guide sheet is located at inside clamshell, and described fin is located at inside lower clamshell; Described block supports fin is in lower clamshell; Described air scoop is located at the air outlet place of chilled air fan and is connected with upper clamshell, forms a gas channel; Described semiconductor chilling plate is positioned in the middle of cool guide sheet and fin, and cool guide sheet is close to by the huyashi-chuuka (cold chinese-style noodles) of described semiconductor chilling plate, and its hot side is close to fin; Described cool guide sheet is connected with fin; Described chilled air fan is located at above cool guide sheet and is close on cool guide sheet; Described radiator fan is located at the lower section of fin and is close on a heat sink.

Described sampling needle assembly includes sampling needle, sampling needle support, sampling needle rotator, sampling needle electric rotating machine, sampling needle up and down motion motor, sampling needle base, sampling needle lifter, Magnet latch segment, described sampling needle lifter is located on sampling needle base, described Magnet latch segment is connected with the rotating shaft of sampling needle up and down motion motor, described rotating shaft is connected with sampling needle lifter, described sampling needle is located on sampling needle support, described sampling needle support and sampling needle rotator connect, described sampling needle rotator is connected with sampling needle electric rotating machine,

Described mixing component includes stirring paddle, stirring paddle support, stirring motor, stirring rotator, stirring electric rotating machine, stirring up and down motion motor, stirring base, stirring lifter, Magnet latch segment, described stirring lifter is located on stirring base, described Magnet latch segment is connected with the rotating shaft of stirring up and down motion motor, described rotating shaft is connected with stirring lifter, described stirring paddle is located on stirring paddle support, described stirring motor is connected with stirring paddle, described stirring paddle support and stirring rotator connect, described stirring rotator is connected with stirring electric rotating machine,

Described cleaning station assembly includes cleaning station support, splined shaft, combined type cleaning pin and cleaning station up and down motion motor, described cleaning station support includes support base plate, support riser, rack plate and support transverse slat, described support riser is located on support base plate, described rack plate is located at the top of support riser, described support riser is provided with cleaning guide rail and cleans slide block, described support transverse slat is located at the middle part of support riser and is fixed on cleaning slide block, described cleaning slide block is located on cleaning guide rail, described cleaning station up and down motion motor is located on support base plate, described splined shaft is connected through rack plate with support transverse slat, described combined type cleaning pin is located on splined shaft, the screw mandrel of described cleaning station up and down motion motor is connected through support transverse slat with the nut on rack plate.

Further technical scheme, described detecting device includes fixed block, optocoupler, spring, pin, catch, described fixed block is provided with chute, described pin is stopper, baffle plate and feeler lever from top to bottom successively, the top of described stopper is located in chute, described spring housing is between the bottom and baffle plate of stopper, and described catch is fixed in stopper and between stopper and optocoupler, and described optocoupler is fixed on fixed block. Described jaw is made up of symmetrical jaw arm and jaws, and jaws is positioned at the end of jaw arm, and described jaws is curved. The lower end inside of described jaw arm is provided with groove.

Described evenly mixing device includes shaking up gear, electric rotating machine, shakes up motor, Timing Belt, connecting rod, central shaft, rotating shaft and eccentric, the top of central shaft is located at by the described gear that shakes up, described electric rotating machine is connected with the bottom of central shaft by Timing Belt, described eccentric is located at and is shaken up on motor, described eccentric is connected with the bottom of central shaft by connecting rod, and described rotating shaft is sheathed on the middle part of central shaft and is fixedly linked with reagent disc.

The described heating plate in incubation dish is affixed on the incubation dish back side by gluing. The bottom of described reaction cup aperture is additionally provided with small sircle hole, and described temperature sensor is fixed in the small sircle hole at the incubation dish back side. The outside of described reaction cup aperture is Openworks shape.

The described motor that seesaws is lead screw motor. Described promotion device includes Magneto separate line slideway and Magneto separate slide block, and described Magneto separate slide block is positioned on Magneto separate line slideway, and described Magneto separate slide block and the nut of lead screw motor are fixedly linked, and described Magneto separate slide block and magnet frame are fixedly linked. The last position of described magnet frame is low level Magnet fixed block, and the described Magnet in low level Magnet fixed block acts on the bottom of reaction cup.

Described measurement apparatus also includes measurement apparatus magnetic receiver, and described measurement apparatus magnetic receiver is located at the outside of measuring chamber, and the primary response cup of itself and rotor is placed position and is located along the same line. Described rotor includes rotor Timing Belt and rotor synchronous pulley, and described rotor synchronous pulley is connected with the rotating shaft of measurement apparatus electric rotating machine, and rotor driven rotates the detecting position making the reaction cup on rotor arrive photomultiplier tube.

Further technical scheme, described refrigeration module also includes heat-preservation cotton, and described heat-preservation cotton is between upper clamshell and lower clamshell. A described bracer is located at fin both sides, and the height of a described bracer is not higher than the contact surface of fin Yu semiconductor chilling plate.

Described refrigeration module also includes fixing seat, and described lower clamshell is connected with base plate by fixing seat, is fixed on base plate by refrigeration module;

Described sampling needle assembly is identical with the Magnet latch segment 13 in mixing component, it includes two contrary annular magnets of magnetic, annular magnet is connected with the rotating shaft of sampling needle up and down motion motor or stirring up and down motion motor, and rotating shaft is connected with the synchronous pulley of sampling needle lifter or stirring lifter.

Described combined type cleaning pin includes cleaning needle shell fragment, cleans punch block, cleaning needle, cleaning needle guard, described cleaning needle is located in cleaning needle guard, described cleaning needle includes injection needle, aspirating needle, one end of described cleaning needle shell fragment is connected with the top cleaning needle guard, its other end is fixing with cleaning punch block to be connected, the syringe needle of described injection needle is connected with flexible pipe, and the syringe needle of described aspirating needle is connected with flexible pipe. Described cleaning punch block is connected with splined shaft. The described top cleaning needle guard is provided with draw-in groove, is used for blocking cleaning needle shell fragment.

Further technical scheme, described X-axis guide assembly includes X-axis rail brackets, X-axis line slideway, X-axis Timing Belt, X-axis synchronizing wheel, X-axis slide block; Described X-axis line slideway is located on X-axis rail brackets, described X-axis slide block is located on X-axis line slideway, described X-axis Timing Belt and X-axis synchronizing wheel drive X-axis slide block to slidably reciprocate on X-axis line slideway, and the rotating shaft of described X-axis synchronizing wheel is connected with X-axis motor; Described Y-axis guide assembly includes Y-axis rail brackets, Y-axis line slideway, Y-axis Timing Belt, Y-axis synchronizing wheel, Y-axis slide block; Described Y-axis line slideway is located on Y-axis rail brackets, described Y-axis slide block is located on Y-axis line slideway, described Y-axis Timing Belt and Y-axis synchronizing wheel drive Y-axis slide block to slidably reciprocate on Y-axis line slideway, and the rotating shaft of described Y-axis synchronizing wheel is connected with y-axis motor; Described Z axis guide assembly includes Z axis polished rod, Z axis linear bearing, Z axis Timing Belt, Z axis synchronizing wheel, described Z axis linear bearing is located on Z axis polished rod, described Z axis Timing Belt and Z axis synchronizing wheel drive Z axis linear bearing to move up and down on Z axis polished rod, and the rotating shaft of described Z axis synchronizing wheel is connected with Z axis motor. Described Y-axis rail brackets is located on X-axis slide block; Described Z axis polished rod is located on Y-axis slide block; Described mechanical gripper is located on Z axis linear bearing.

Described lucite lid is provided with thieff hatch and handle, plexiglass cover and thermal insulation cover and seals cooperation. Described thieff hatch is curved, matches with the putting position of reagent bottle.

Described reagent sample disk and incubation device also include drip tray, and described drip tray is positioned at the lower section of sample disk or incubation dish and is positioned at sample pore or the underface of reaction cup aperture.

Described magnet frame is in sector.

The described axle renovating motor is provided with eccentric, and described eccentric drives measurement apparatus connecting rod, being opened by what the control of measurement apparatus connecting rod was renovated and being closed.

Further technical scheme, the described radiator fan in refrigeration module has two, and the blade installation direction of two radiator fans is contrary, is provided with dividing plate between two radiator fans. Described dividing plate is fixed in lower clamshell, and its lower plane is equal with the bottom surface of lower clamshell, and upper plane connects with the tooth top of fin.

The end of described sampling needle is provided with flange copper sheet.

Described sampling needle lifter and stirring lifter all include Timing Belt, synchronous pulley and guide rail, and described synchronous pulley is connected with the rotating shaft of sampling needle up and down motion motor or stirring up and down motion motor. Described sampling needle rotator and stirring rotator all include Timing Belt, synchronous pulley, and described synchronous pulley is connected with the rotating shaft of sampling needle electric rotating machine or stirring electric rotating machine.

Further technical scheme, the side of described thermal insulation cover is provided with detection mouth.

Described incubation dish adopts pure aluminum material.

Described Magneto separate support is provided with Magneto separate lifter and Magneto separate lifting motor.

Further technical scheme, the upper clamshell in described refrigeration module is connected by screw with lower clamshell. Described cool guide sheet is connected with fin by plastic screw.

Further technical scheme, described cleaning needle has at least one. Described aspirating needle is longer than injection needle, and the syringe needle of injection needle bends to aspirating needle direction. Described cleaning needle shell fragment is spring steel plate.

The workflow of the present invention is:

1, after the analyzer of the present invention is powered by power module, after modules initializes, work is proceeded by;

2, refrigeration module for be reagent sample disk provide cold air ensure that reagent is in low temperature environment;

3, mechanical arm module captures reaction cup from reaction glass stand and is put into the first-class sample to be added of incubation dish and reagent successively;

4, incubation dish turns to reaction cup the position of application of sample, and sampling needle assembly draws sample inside reagent sample disk and reagent is injected into reaction cup, and then incubation coil motor turns to the position of mixing component and is stirred and carries out incubation;

5, after incubation completes, reaction cup forwards to and carries out Magneto separate at Magneto separate module position, enters cleaning station and be carried out after repeatedly Magneto separate;

When 6, cleaning, Magneto separate assembly leans against Magnet in reaction cup, and cleaning station blots the liquid inside reaction cup and injects new washing liquid afterwards, drains and turn to the continuation cleaning of next lattice after waiting 30s, after repeatedly cleaning, reaction cup is put into measuring chamber measurement by mechanical arm module;

7, after measurement terminates, mechanical arm module takes out reaction cup, puts into useless cup gathering station, completes measurement process.

Beneficial effect

Compared with prior art, the present invention possesses following remarkable advantage:

1, the present invention is fully-automated synthesis instrument, it is not necessary to manual intervention, completes the programs such as the mixing to testing sample, reaction, incubation, Magneto separate, detection according to preset program, and directly exports data, substantially increases detection efficiency, it is to avoid error occurs.

2, the mechanical arm simple structure of the present invention, is respectively provided with motor respectively in the X, Y, Z direction, controls motion in X, Y, Z-direction, and trace arrangements is simple, it is not easy to cause circuit dislocation, if the component malfunction in one of them direction, it is only necessary to individually keep in repair; And when using, the regulation and control of position are convenient, accurate positioning, it is possible to meet the accurate high efficiency requirement of height capturing work; Mechanical gripper is provided with detecting device and is connected by structure cleverly, it is possible to detect whether, when jaw captures, the cup that responds, if having, then complete to capture work, capturing if not having mechanical gripper to move to next position, it is to avoid empty pawl phenomenon, improve detection efficiency; Structure of the detecting device is simple, highly sensitive, and jaw efficiently coordinates, and improves the work efficiency of crawl. The lower end inside of jaw arm is provided with groove, and jaws is curved that jaw can be allowed to fit tightly reaction cup, folder very firm, it is possible to the bottleneck of clamping reaction cup steadily, difficult drop-off.

3, the refrigeration of the refrigerating plant of the present invention has respective air path system respectively with heat radiation, does not interfere with each other, and can be effectively accomplished reagent refrigerating requirement soon. Chilled air fan is located at above cool guide sheet and is close on cool guide sheet so that the cold air of generation flows into the agent bin of cold room by air scoop, while realizing refrigeration cool-down, also forms forced convection, effectively prevent the formation of condensed water. Two radiator fans one blow and take out, and form a set of quick air-flow exchange system with external environment, it is achieved fast cooling. Semiconductor chilling plate is positioned in the middle of cool guide sheet and fin, and cool guide sheet is close to by the huyashi-chuuka (cold chinese-style noodles) of described semiconductor chilling plate, and its hot side is close to fin; Described cool guide sheet is connected with fin, it is achieved also ensure cool guide sheet and fin and semiconductor chilling plate close contact while fixing semiconductor chilling plate. Prop up block supports fin in lower clamshell, thus by whole interior structural support. Radiator fan is located at the lower section of fin and is close on a heat sink, is transported in external environment by hot blast, realizes the cooling function to fin.

4, sample disk and reagent disc are concentrated in together by the reagent sample disk of the present invention, so can save space, and reduce sampling needle device, it is only necessary to a sampling needle just can complete sampling. Evenly mixing device adopts an electric rotating machine direction always to rotate, and coordinates with shaking up motor, it is achieved repeat back and forth to shake up magnetic bead, and motor so can be allowed to be not easy hot and be not easy to damage. Lucite lid is provided with thieff hatch and handle, facilitates application of sample and changes reagent bottle. Plexiglass cover and thermal insulation cover seal and coordinate, it is ensured that reagent is under set point of temperature, ensure the effectiveness of reagent. Thieff hatch is curved, matches with the putting position of reagent bottle, and sampling needle application of sample is convenient.

5, the sampling needle assembly of the present invention and mixing component can allow sampling needle assembly and mixing component in normal operation when meeting with unexpected power-off to start locking function, prevent lifter moment from dropping, sampling needle and stirring paddle is avoided to damage, and the work before again can continuing after energising, improve work efficiency, the service life of extension fixture. When power is off, the magnetic force that two annular magnets of Magnet latch segment produce can retrain rotating shaft, by locking lifter, it is to avoid rotating shaft causes that because moment is out of control lifter moment falls and drives sampling needle and stirring paddle to drop and cause damage. The end of sampling needle is provided with flange copper sheet, and solderable wire on flange copper sheet, for the Level Detection of sampling needle.

6, equipped with conducting slip ring device under the incubation dish of the incubation device of the present invention, the line of heating plate and temperature sensor is to be connected on conducting slip ring, effectively solve the problem that rotating disc type causes circuit to be wound around, and save space, make heating plate can be affixed on the incubation dish back side either directly through gluing, it is achieved quickly to heat. Incubation device controls temperature by temperature sensor, and keeping incubation dish is temperature constant state, is affected only small by extraneous factor so that measurement data is more accurate. Incubation dish is pure aluminum material, and heat conductivity is good, it is possible to realize quickly heating. The outside of the reaction cup aperture on incubation dish is Openworks shape, is conducive to coordinating Magneto separate operation. The drip tray of incubation device and reagent sample disk is located at below incubation dish and sample disk, and it is positioned at the underface of reaction cup aperture and sample pore, when reaction cup and sample tube generation leakage situation, it is possible to effectively prevent reagent from outflowing, it is to avoid the generation of security incident problem.

7, each Magnet of the Magneto separate assembly of the present invention is fixed in Magnet fixed block, spring assembly is had after Magnet fixed block, so when Magnet sticks reaction cup, there is a cushioning effect, ensure it is not run into very stiff and demandingly, each Magnet and reaction cup can also be made to fit tightly after adjusting bonding position, Magneto separate better effects if. Magnet acts on the side of reaction cup close to bottom place, it is possible to effectively prevent from taking magnetic bead away during drawing liquid bottom liquid pumping needle insertion reaction cup, is prevented effectively from magnetic bead and runs off. After Magneto separate completes, carry out drawing liquid, during drawing liquid, Magnet is still attached in reaction cup, after drawing liquid, magnet frame there is a low level Magnet in last low level Magnet fixed block, low level Magnet Magneto separate is completed after reaction cup in magnetic bead move reaction cup bottommost to, so send to measuring chamber measure time inject excimer time, react more abundant, avoid magnetic bead on reaction wall of cup, it is impossible to fully to react. Magnet frame contributes to, in sector, the incubation dish that laminating is circular, improves Magneto separate effect.

8, the cleaning station assembly of the present invention is blotted the liquid inside reaction cup by aspirating needle, the syringe needle of injection needle bends to aspirating needle direction, injection needle injects cleanout fluid, injection needle just can be cleaned aspirating needle when injecting, aspirating needle also plays drainage, liquid splash when simultaneously preventing fluid injection. Cleaning needle has cleaning needle shell fragment, when cleaning needle is encountered bottom reaction cup time, has the effect of buffering, effectively prevent aspirating needle because bottoming out the damage that collision causes, extend the service life of aspirating needle, improve work efficiency. The quantity of cleaning needle can suitably increase according to actual needs, improves work efficiency. Up and down motion motor in cleaning station assembly realizes moving up and down by controlling splined shaft, such that it is able to the position of flexible dispatching combined type cleaning pin, it is simple to imbibition and fluid injection, make cleaning more convenient.

9, the measuring chamber of the present invention adopts flip-shell to close, and when reaction cup is put in measuring chamber, renovates and covers one airtight reaction darkroom of formation, and light-shading effect is good and saves space so that measure precisely. Rotor is provided with some reaction cup and places position, it is possible to meet the demand that multiple reaction cup is measured, it is achieved automatically working, it is possible to more efficient rapid measurement, reduces manual operation, it is to avoid cause problem of artificially makeing mistakes. Before reaction cup puts into measuring chamber, first reaction cup is placed on magnetic receiver, it is possible to the magnetic bead in reaction cup is moved to bottom reaction cup, it is possible to react fully, places into measurement in measuring chamber, it is ensured that measure accurately, be substantially reduced CV value.

Accompanying drawing explanation

Fig. 1 is the structural representation of the present invention;

Fig. 2 is the structural representation of mechanical arm module in the present invention;

Fig. 3 is the enlarged drawing of the X-axis guide assembly of mechanical arm module in the present invention;

Fig. 4 is the enlarged drawing of the Y-axis guide assembly of mechanical arm module in the present invention;

Fig. 5 is the enlarged drawing of the Z axis guide assembly of mechanical arm module in the present invention;

Fig. 6 is the enlarged drawing of the mechanical gripper of mechanical arm module in the present invention;

Fig. 7 is the enlarged drawing of the lever of the mechanical gripper of mechanical arm module in the present invention;

Fig. 8 is the external structure schematic diagram of refrigeration module in the present invention;

Fig. 9 is the internal structure schematic diagram of refrigeration module in the present invention;

Figure 10 is the enlarged drawing of the cool guide sheet of refrigeration module in the present invention and fin;

Figure 11 is the external structure schematic diagram of reagent sample disk in the present invention;

Figure 12 is the internal structure schematic diagram of reagent sample disk in the present invention;

Figure 13 is the structural representation of the evenly mixing device of reagent sample disk in the present invention;

Figure 14 is the structural representation of sampling needle assembly in the present invention;

Figure 15 is the enlarged drawing of the sampling needle of sampling needle assembly in the present invention and sampling needle support;

Figure 16 is the structural representation of mixing component in the present invention;

Figure 17 is the enlarged drawing of the Magnet latch segment of sampling needle assembly and mixing component in the present invention;

Figure 18 is the structural representation of incubation device in the present invention;

Figure 19 is the sectional view of incubation device in the present invention;

Figure 20 is the back view of incubation dish in the present invention;

Figure 21 is the structural representation of Magneto separate assembly in the present invention;

Figure 22 is the enlarged drawing of the magnet frame of Magneto separate assembly in the present invention;

Figure 23 is the enlarged drawing promoting device of Magneto separate assembly in the present invention;

Figure 24 is the structural representation of cleaning station assembly in the present invention;

Figure 25 is the structural representation of the combined type cleaning pin of cleaning station assembly in the present invention;

Figure 26 is the structural representation of measurement apparatus in the present invention;

Figure 27 is the top view of measurement apparatus in the present invention;

Figure 28 is the enlarged drawing of the rotor of measurement apparatus in the present invention;

Number in the figure illustrates:

1, mechanical arm module, 2, refrigeration module, 3, power module, 4, reagent sample disk, 5, sampling needle assembly, 6, mixing component, 7, reaction glass stand, 8, incubation device 9, Magneto separate assembly, 10, cleaning station assembly, 11, measuring chamber;

1-1, X-axis guide assembly, 1-2, Y-axis guide assembly, 1-3, Z axis guide assembly, 1-4, X-axis motor, 1-5, y-axis motor, 1-6, Z axis motor, 1-7, mechanical gripper, 1-8, mechanical gripper motor, 1-7-1, fixed block, 1-7-2, optocoupler, 1-7-3, spring, 1-7-4, pin, 1-7-4-1, stopper, 1-7-4-2, baffle plate, 1-7-4-3, feeler lever, 1-7-5, catch, 1-7-6, jaw; 1-1-1, X-axis rail brackets, 1-1-2, X-axis line slideway, 1-1-3, X-axis Timing Belt, 1-1-4, X-axis slide block, 1-2-1, Y-axis rail brackets, 1-2-2, Y-axis line slideway, 1-2-3, Y-axis Timing Belt, 1-2-4, Y-axis slide block; 1-3-1, Z axis polished rod, 1-3-2, Z axis linear bearing, 1-3-3, Z axis Timing Belt, 1-3-4, Z axis synchronizing wheel;

2-1, air scoop, 2-2, upper clamshell, 2-3, lower clamshell, 2-4, semiconductor chilling plate, 2-5, radiator fan, 2-6, chilled air fan, 2-7, cool guide sheet, 2-8, a bracer, 2-9, fin, 2-10, heat-preservation cotton, 2-11, fixing seat, 2-12, dividing plate, 2-13, plastic screw;

4-1, evenly mixing device, 4-1-1, shake up gear, 4-1-2, electric rotating machine, 4-1-3, shakes up motor, 4-1-4, Timing Belt, 4-1-5, connecting rod, 4-1-6, central shaft, 4-1-7, rotating shaft, 4-1-8, eccentric, 4-2, thermal insulation cover, 4-2-1, refrigeration window, 4-2-2, detection mouth, 4-3, plexiglass cover, 4-3-1, thieff hatch, 4-3-2, handle, 4-4, sample disk, 4-5, reagent disc, 4-6, sample disk support, 4-7, sample pore, 12, drip tray;

5-1 sampling needle, 5-2, sampling needle support, 5-3, sampling needle rotator, 5-4, sampling needle electric rotating machine, 5-5, sampling needle up and down motion motor, 5-6, sampling needle base, 5-7, sampling needle lifter, 13, Magnet latch segment, 5-9, flange copper sheet;

6-1, stirring paddle, 6-2, stirring paddle support, 6-3, stirring motor, 6-4, stirring rotator, 6-5, stirring electric rotating machine, 6-6, stirring up and down motion motor, 6-7, stirring base, 6-8, stirring lifter;

8-1, incubation dish, 8-2, conducting slip ring, 8-3, rotary tray motor, 8-4, heating plate, 8-5, temperature sensor, 8-6, incubation disc carrier, 8-7, reaction cup aperture;

9-1, seesaw motor, 9-2, promotes device, 9-2-1, Magneto separate line slideway, 9-2-2, Magneto separate slide block, 9-3, magnet frame, 9-4, Magnet, 9-5, Magnet fixed block, 9-6, Magneto separate support, 9-7, Magneto separate base, 9-8, spring assembly, 9-9, low level Magnet fixed block, 9-10, magnetic receiver, 9-11, nut;

10-1, cleaning station support, 10-2, splined shaft, 10-3, combined type cleaning pin, 10-4, cleaning station up and down motion motor, 10-1-1, support base plate, 10-1-2, support riser, 10-1-3, rack plate, 10-1-4 support transverse slat, 10-5, cleaning slide block, 10-6, cleaning guide rail, 10-3-1, cleaning needle shell fragment, 10-3-2, cleaning punch block, 10-3-3, cleaning needle, 10-3-4, cleaning needle guard, 10-3-3-1, injection needle, 10-3-3-2, aspirating needle, 10-3-5, draw-in groove;

11-1, photomultiplier tube, 11-2, renovate motor, 11-3, renovates, 11-4, measurement apparatus electric rotating machine, 11-5, measuring chamber, 11-6, strengthens liquid filler, 11-7, measurement apparatus connecting rod, 11-8, rotor, 11-9, magnetic receiver.

Detailed description of the invention

Below in conjunction with drawings and Examples, the present invention is further detailed explanation.

Embodiment

As shown in Fig. 1 to Figure 28, a kind of Full-automatic chemiluminescence analyzer, including mechanical arm module 1, refrigeration module 2, power module 3, reagent sample disk 4, sampling needle assembly 5, mixing component 6, reaction glass stand 7, incubation device 8, Magneto separate assembly 9, cleaning station assembly 10, measurement apparatus 11;

Described mechanical arm module 1 for capturing reaction cup in three dimensions;

Described refrigeration module 2 provides low temperature environment for reagent sample disk;

Described power module 3 is analyzer running power supply;

Described reagent sample disk 4 is used for placing sample tube and reagent bottle;

Sample liquid in reagent sample disk 4 or reagent are injected in the reaction cup in incubation device 8 by described sampling needle assembly 5;

Reaction cup in incubation device 8 is stirred by described mixing component 6;

Described reaction glass stand 7 is easy to mechanical arm module 1 for placing response cup and is captured reaction cup;

Described incubation device 8 provides isoperibol for reaction cup;

Reaction cup on incubation device 8 is carried out Magneto separate by described Magneto separate assembly 9;

Reaction cup after Magneto separate is carried out by described cleaning station assembly 10;

Described measurement apparatus 11 is to the reaction cup measurement after cleaning.

Described mechanical arm module 1 includes X-axis guide assembly 1-1, Y-axis guide assembly 1-2, Z axis guide assembly 1-3, X-axis motor 1-4, y-axis motor 1-5, Z axis motor 1-6, mechanical gripper 1-7 and mechanical gripper motor 1-8, described X-axis guide assembly 1-1 is connected with X-axis motor 1-4, described Y-axis guide assembly 1-2 is connected with y-axis motor 1-5, described Z axis guide assembly 1-3 is connected with Z axis motor 1-6, and described mechanical gripper 1-7 is connected with mechanical gripper motor 1-8; Described Y-axis guide assembly 1-2 is located on X-axis guide assembly 1-1, and described Z axis guide assembly 1-3 is located on Y-axis guide assembly 1-2, and described mechanical gripper 1-7 is located on Z axis guide assembly 1-3; Described mechanical gripper 1-7 includes jaw 1-7-6, detecting device, and described detecting device is located at above jaw 1-7-6.

Described reagent sample disk 4 includes evenly mixing device 4-1, thermal insulation cover 4-2, plexiglass cover 4-3, sample disk 4-4, reagent disc 4-5, sample disk support 4-6; Described sample disk 4-4 is located on sample disk support 4-6, described evenly mixing device 4-1 is positioned at the lower section of sample disk 4-4, described reagent disc 4-5 is positioned at the inside of sample disk 4-4, described thermal insulation cover 4-2 is located at the periphery of sample disk 4-4, described plexiglass cover 4-3 is located on thermal insulation cover 4-2 and seals with thermal insulation cover 4-2 and coordinates, the circumference outer ring of described sample disk 4-4 is provided with sample pore 4-7, the side of described thermal insulation cover 4-2 is provided with refrigeration window 4-2-1, described refrigeration window 4-2-1 and refrigeration module 2 seals and coordinates.

Described incubation device 8 includes incubation dish 8-1, conducting slip ring 8-2, rotary tray motor 8-3, heating plate 8-4, temperature sensor 8-5, incubation disc carrier 8-6, described incubation dish 8-1 is located on incubation disc carrier 8-6, and the back side of described incubation dish 8-1 is provided with heating plate 8-4 and temperature sensor 8-5; Described conducting slip ring 8-2 is located at the center of incubation dish 8-1, and the wire of heating plate 8-4 and temperature sensor 8-5 is all wrapped on conducting slip ring 8-2; The axle that rotates of described rotary tray motor 8-3 is connected with the center of incubation dish 8-1; The round edge of described incubation dish 8-1 is provided with some reaction cup aperture 8-7.

Described Magneto separate assembly 9 includes the motor 9-1 that seesaws, promote device 9-2, magnet frame 9-3, Magnet 9-4, Magnet fixed block 9-5, Magneto separate support 9-6, Magneto separate base 9-7, spring assembly 9-8, described magnet frame 9-3 is connected with the motor 9-1 that seesaws by promoting device 9-2, magnet frame 9-3 is provided with some magnetic receiver 9-10, described Magnet fixed block 9-5 is located in magnetic receiver 9-10, described Magnet 9-4 is located at the side simultaneously acting on reaction cup in Magnet fixed block 9-5 close to bottom place, the described motor 9-1 that seesaws, device 9-2 and magnet frame 9-3 is promoted all to be located on Magneto separate support 9-6, described Magneto separate support 9-6 is located on Magneto separate base 9-7, described spring assembly 9-8 is located at inside magnetic receiver 9-10, and be positioned at after Magnet fixed block 9-5.

Described measurement apparatus 11 includes photomultiplier tube 11-1, renovate motor 11-2, renovate 11-3, measurement apparatus electric rotating machine 11-4, measuring chamber 11-5, strengthen liquid filler 11-6, described photomultiplier tube 11-1 is connected with measuring chamber 11-5, the described motor 11-2 that renovates is connected with renovating 11-3 by measurement apparatus connecting rod 11-7, it is provided with rotor 11-8 inside described measuring chamber 11-5, rotor 11-8 is provided with some reaction cup and places position 11-8-1, described rotor 11-8 includes a primary response cup and places position and a detection reaction cup placement position, described primary response cup is placed position and is positioned at the underface of measuring chamber 11-5 opening, described detection reaction cup is placed position and is positioned on the detecting position of measuring chamber 11-5, the described opening renovating 11-3 and measuring chamber 11-5 seals cooperation makes whole measuring chamber 11-5 be internally formed sealing space, described measurement apparatus electric rotating machine 11-4 is connected with rotor 11-8, described strengthens the liquid filler 11-6 top being arranged in the detecting position of measuring chamber 11-5.

Described refrigeration module 2 includes air scoop 2-1, upper clamshell 2-2, lower clamshell 2-3, semiconductor chilling plate 2-4, radiator fan 2-5, chilled air fan 2-6, cool guide sheet 2-7, a bracer 2-8 and fin 2-9; Described upper clamshell 2-2 is connected with lower clamshell 2-3; Described cool guide sheet 2-7 is located at inside clamshell 2-2, and described fin 2-9 is located at inside lower clamshell 2-3; Described bracer 2-8 supports fin 2-9 in lower clamshell 2-3; Described air scoop 2-1 is located at the air outlet place of chilled air fan 2-6 and is connected with upper clamshell 2-2, forms a gas channel; Described semiconductor chilling plate 2-4 is positioned in the middle of cool guide sheet 2-7 and fin 2-9, and cool guide sheet 2-7 is close to by the huyashi-chuuka (cold chinese-style noodles) of described semiconductor chilling plate 2-4, and its hot side is close to fin 2-9; Described cool guide sheet 2-7 is connected with fin 2-9; Described chilled air fan 2-6 is located at above cool guide sheet 2-7 and is close on cool guide sheet 2-7; Described radiator fan 2-5 is located at the lower section of fin 2-9 and is close on fin 2-9.

Described sampling needle assembly 5 includes sampling needle 5-1, sampling needle support 5-2, sampling needle rotator 5-3, sampling needle electric rotating machine 5-4, sampling needle up and down motion motor 5-5, sampling needle base 5-6, sampling needle lifter 5-7, Magnet latch segment 13, described sampling needle lifter 5-7 is located at 5-6 on sampling needle base, described Magnet latch segment 13 is connected with the rotating shaft of sampling needle up and down motion motor 5-5, described rotating shaft is connected with sampling needle lifter 5-7, described sampling needle 5-1 is located on sampling needle support 5-2, described sampling needle support 5-2 and sampling needle rotator 5-3 connects, described sampling needle rotator 5-3 is connected with sampling needle electric rotating machine 5-4.

Described mixing component 6 includes stirring paddle 6-1, stirring paddle support 6-2, stirring motor 6-3, stirring rotator 6-4, stirring electric rotating machine 6-5, stirring up and down motion motor 6-6, stirring base 6-7, stirring lifter 6-8, Magnet latch segment 13, described stirring lifter 6-8 is located on stirring base 6-7, described Magnet latch segment 13 is connected with the rotating shaft of stirring up and down motion motor 6-6, described rotating shaft is connected with stirring lifter 6-8, described stirring paddle 6-1 is located on stirring paddle support 6-2, described stirring motor is connected with stirring paddle 6-1, described stirring paddle support 6-2 and stirring rotator 6-4 connects, described stirring rotator 6-4 is connected with stirring electric rotating machine 6-5.

Described cleaning station assembly includes cleaning station support 10-1, splined shaft 10-2, combined type cleaning pin 10-3 and cleaning station up and down motion motor 10-4, described cleaning station support 10-1 includes support base plate 10-1-1, support riser 10-1-2, rack plate 10-1-3 and support transverse slat 10-1-4, described support riser 10-1-2 is located on support base plate 10-1-1, described rack plate 10-1-3 is located at the top of support riser 10-1-2, described support riser 10-1-2 is provided with cleaning guide rail 10-6 and cleans slide block 10-5, described support transverse slat 10-1-4 is located at the middle part of support riser 10-1-2 and is fixed on cleaning slide block 10-5, described cleaning slide block 10-5 is located on cleaning guide rail 10-6, described cleaning station up and down motion motor 10-4 is located on support base plate 10-1-1, described splined shaft 10-2 is connected through rack plate 10-1-3 with support transverse slat 10-1-4, described combined type cleaning pin 10-3 is located on splined shaft 10-2, the screw mandrel of the cleaning station up and down motion motor 10-4 that institute 10-1-3 states is connected through support transverse slat 10-1-4 with the nut on rack plate.

Described detecting device includes fixed block 1-7-1, optocoupler 1-7-2, spring 1-7-3, pin 1-7-4, catch 1-7-5, described fixed block 1-7-1 is provided with chute, described pin 1-7-4 is stopper 1-7-4-1 from top to bottom successively, baffle plate 1-7-4-2 and feeler lever 1-7-4-3, the top of described stopper 1-7-4-1 is located in chute, described spring 1-7-3 is enclosed between the bottom of stopper 1-7-4-1 and baffle plate 1-7-4-2, described catch 1-7-5 is fixed on stopper 1-7-4-1 and between stopper 1-7-4-1 and optocoupler 1-7-2, described optocoupler 1-7-2 is fixed on fixed block 1-7-1. described jaw 1-7-6 is made up of symmetrical jaw arm and jaws, and jaws is positioned at the end of jaw arm, and described jaws is curved. the lower end inside of described jaw arm is provided with groove.

Described evenly mixing device 4-1 includes shaking up gear 4-1-1, electric rotating machine 4-1-2, shake up motor 4-1-3, Timing Belt 4-1-4, connecting rod 4-1-5, central shaft 4-1-6, rotating shaft 4-1-7 and eccentric 4-1-8, the described gear 4-1-1 that shakes up is located at the top of central shaft 4-1-6, described electric rotating machine 4-1-2 is connected by the bottom of Timing Belt 4-1-4 and central shaft 4-1-6, described eccentric 4-1-8 is located at and shakes up on motor 4-1-3, described eccentric 4-1-8 is connected by the bottom of connecting rod 4-1-5 and central shaft 4-1-6, described rotating shaft 4-1-7 is sheathed on the middle part of central shaft 4-1-6 and is fixedly linked with reagent disc 4-5.

The described heating plate 8-4 in incubation dish is affixed on the incubation dish 8-1 back side by gluing. The bottom of described reaction cup aperture 8-7 is additionally provided with small sircle hole, and described temperature sensor 8-5 is fixed in the small sircle hole at the incubation dish 8-1 back side. The outside of described reaction cup aperture 8-7 is Openworks shape.

The described motor 9-1 that seesaws is lead screw motor. Described promotion device 9-2 includes Magneto separate line slideway 9-2-1 and Magneto separate slide block 9-2-2, described Magneto separate slide block 9-2-2 is positioned on Magneto separate line slideway 9-2-1, described Magneto separate slide block 9-2-2 and the nut 9-11 of lead screw motor is fixedly linked, and described Magneto separate slide block 9-2-2 and magnet frame 9-3 is fixedly linked. The last position of described magnet frame 9-3 is low level Magnet fixed block 9-9, and the described Magnet in low level Magnet fixed block 9-9 acts on the bottom of reaction cup.

Described measurement apparatus 11 also includes measurement apparatus magnetic receiver 11-9, and described measurement apparatus magnetic receiver 11-9 is located at the outside of measuring chamber 11-5, and the primary response cup of itself and rotor 11-8 is placed position and is located along the same line. Described rotor 11-8 includes the rotating shaft of rotor Timing Belt and rotor synchronous pulley, described rotor synchronous pulley and measurement apparatus electric rotating machine 11-4 and is connected, and rotor driven 11-8 rotates the detecting position making the reaction cup on rotor 11-8 arrive photomultiplier tube 11-1.

Described refrigeration module 2 also includes heat-preservation cotton 2-10, described heat-preservation cotton 2-10 between upper clamshell 2-2 and lower clamshell 2-3. A described bracer 2-8 is located at fin 2-9 both sides, the height of the described bracer 2-8 contact surface not higher than fin 2-9 Yu semiconductor chilling plate 2-4.

Described refrigeration module 2 is also included fixing seat 2-11, described lower clamshell 2-3 and is connected with base plate by fixing seat 2-11, is fixed on base plate by refrigeration module 2;

Described sampling needle assembly is identical with the Magnet latch segment 13 in mixing component, it includes two contrary annular magnets of magnetic, annular magnet is connected with the rotating shaft of sampling needle up and down motion motor 5-5 or stirring up and down motion motor 6-6, and rotating shaft is connected with the synchronous pulley of sampling needle lifter 5-7 or stirring lifter 6-8.

Described combined type cleaning pin includes cleaning needle shell fragment 10-3-1, cleaning punch block 10-3-2, cleaning needle 10-3-3, cleans needle guard 10-3-4, described cleaning needle 10-3-3 is located in cleaning needle guard 10-3-4, described cleaning needle 10-3-3 includes injection needle 10-3-3-1, aspirating needle 10-3-3-2, one end of described cleaning needle shell fragment 10-3-1 is connected with the top cleaning needle guard 10-3-4, its other end is fixing with cleaning punch block 10-3-2 to be connected, the syringe needle of described injection needle 10-3-3-1 is connected with flexible pipe, and the syringe needle of described aspirating needle 10-3-3-2 is connected with flexible pipe. Described cleaning punch block 10-3-2 is connected with splined shaft 10-2. The described top cleaning needle guard 10-3-4 is provided with draw-in groove 10-3-5, is used for blocking cleaning needle shell fragment 10-3-1.

Described X-axis guide assembly 1-1 includes X-axis rail brackets 1-1-1, X-axis line slideway 1-1-2, X-axis Timing Belt 1-1-3, X-axis synchronizing wheel, X-axis slide block 1-1-4; Described X-axis line slideway 1-1-2 is located on X-axis rail brackets 1-1-1, described X-axis slide block 1-1-4 is located at 1-1-2 on X-axis line slideway, described X-axis Timing Belt 1-1-3 and X-axis synchronizing wheel drive X-axis slide block 1-1-4 to slidably reciprocate on X-axis line slideway 1-1-2, and the rotating shaft of described X-axis synchronizing wheel is connected with X-axis motor 1-4. Described Y-axis guide assembly 1-2 includes Y-axis rail brackets 1-2-1, Y-axis line slideway 1-2-2, Y-axis Timing Belt 1-2-3, Y-axis synchronizing wheel, Y-axis slide block 1-2-4; Described Y-axis line slideway 1-2-2 is located on Y-axis rail brackets 1-2-1, described Y-axis slide block 1-2-4 is located on Y-axis line slideway 1-2-2, described Y-axis Timing Belt 1-2-3 and Y-axis synchronizing wheel drive Y-axis slide block 1-2-4 to slidably reciprocate on Y-axis line slideway 1-2-3, and the rotating shaft of described Y-axis synchronizing wheel is connected with y-axis motor 1-5. Described Z axis guide assembly 1-3 includes Z axis polished rod 1-3-1, Z axis linear bearing 1-3-2, Z axis Timing Belt 1-3-3, Z axis synchronizing wheel 1-3-4, described Z axis linear bearing 1-3-2 is located on Z axis polished rod 1-3-1, described Z axis Timing Belt 1-3-3 and Z axis synchronizing wheel 1-3-4 drives Z axis linear bearing 1-3-2 to move up and down on Z axis polished rod 1-3-1, and the rotating shaft of described Z axis synchronizing wheel 1-3-4 is connected with Z axis motor 1-6. Described Y-axis rail brackets 1-2-1 is located on X-axis slide block 1-1-4; Described Z axis polished rod 1-3-1 is located on Y-axis slide block 1-2-4; Described mechanical gripper 1-7 is located on Z axis linear bearing 1-3-2.

Described plexiglass cover 4-3 is provided with thieff hatch 4-3-1 and handle 4-3-2, plexiglass cover 4-3 and thermal insulation cover 4-2 and seals cooperation. Described thieff hatch 4-3-1 is curved, matches with the putting position of reagent bottle.

Described reagent sample disk 4 and incubation device 8 also include drip tray 12, and described drip tray 12 is positioned at the lower section of sample disk 4-4 or incubation dish 8-1 and is positioned at sample pore 4-7 or the underface of reaction cup aperture 8-7.

Described magnet frame 9-3 is in sector.

The described axle renovating motor 11-2 is provided with eccentric 11-10, and described eccentric 11-10 drives measurement apparatus connecting rod 11-7, controls to renovate opening and closing of 11-3 by measurement apparatus connecting rod 11-7.

The described radiator fan 2-5 in refrigeration module 2 has two, and the blade installation direction of two radiator fan 2-5 is contrary, is provided with dividing plate 2-12 between two radiator fan 2-5. Described dividing plate 2-12 is fixed in lower clamshell 2-3, and its lower plane is equal with the bottom surface of lower clamshell 2-3, and upper plane connects with the tooth top of fin 2-9.

The end of described sampling needle 5-1 is provided with flange copper sheet 5-9.

Described sampling needle lifter 5-7 and stirring lifter 6-8 all includes Timing Belt, synchronous pulley and guide rail, and described synchronous pulley is connected with the rotating shaft of sampling needle up and down motion motor 5-5 or stirring up and down motion motor 6-6. Described sampling needle rotator 5-3 and stirring rotator 6-4 all includes Timing Belt, synchronous pulley, and described synchronous pulley is connected with the rotating shaft of sampling needle electric rotating machine 5-4 or stirring electric rotating machine 6-5.

The side of described thermal insulation cover 4-2 is provided with detection mouth 4-2-2.

Described incubation dish 8-1 adopts pure aluminum material.

Described Magneto separate support 9-6 is provided with Magneto separate lifter and Magneto separate lifting motor.

Upper clamshell 2-2 in described refrigeration module 2 is connected by screw with lower clamshell 2-3. Described cool guide sheet 2-7 is connected with fin 2-9 by plastic screw 2-13.

Described cleaning needle 10-3-3 has at least one. Described aspirating needle 10-3-3-2 is longer than injection needle 10-3-3-1, and the syringe needle of injection needle 10-3-3-1 bends to aspirating needle 10-3-3-2 direction. Described cleaning needle shell fragment 10-3-1 is spring steel plate.

Claims (10)

1. a Full-automatic chemiluminescence analyzer, it is characterized in that, including mechanical arm module, refrigeration module, power module, reagent sample disk, sampling needle assembly, mixing component, reaction glass stand, incubation device, Magneto separate assembly, cleaning station assembly, measurement apparatus;

Described mechanical arm module for capturing reaction cup in three dimensions;

Described refrigeration module provides low temperature environment for reagent sample disk;

Described power module is analyzer running power supply;

Described reagent sample disk is used for placing sample tube and reagent bottle;

Sample liquid in reagent sample disk or reagent are injected in the reaction cup in incubation device by described sampling needle assembly;

Reaction cup in incubation device is stirred by described mixing component;

Described reaction glass stand is easy to mechanical arm module for placing response cup and is captured reaction cup;

Described incubation device provides isoperibol for reaction cup;

Reaction cup on incubation device is carried out Magneto separate by described Magneto separate assembly;

Reaction cup after Magneto separate is carried out by described cleaning station assembly;

Described measurement apparatus is to the reaction cup measurement after cleaning.

2. a kind of Full-automatic chemiluminescence analyzer according to claim 1, it is characterized in that, described mechanical arm module includes X-axis guide assembly, Y-axis guide assembly, Z axis guide assembly, X-axis motor, y-axis motor, Z axis motor, mechanical gripper and mechanical gripper motor, described X-axis guide assembly is connected with X-axis motor, described Y-axis guide assembly is connected with y-axis motor, described Z axis guide assembly is connected with Z axis motor, and described mechanical gripper is connected with mechanical gripper motor; Described Y-axis guide assembly is located on X-axis guide assembly, and described Z axis guide assembly is located on Y-axis guide assembly, and described mechanical gripper is located on Z axis guide assembly; Described mechanical gripper includes jaw, detecting device, and described detecting device is located at above jaw;

Described reagent sample disk includes evenly mixing device, thermal insulation cover, plexiglass cover, sample disk, reagent disc, sample disk support; Described sample disk is located on sample disk support, described evenly mixing device is positioned at the lower section of sample disk, described reagent disc is positioned at the inside of sample disk, described thermal insulation cover is located at the periphery of sample disk, described lucite is covered on thermal insulation cover and seals with thermal insulation cover and coordinates, the circumference outer ring of described sample disk is provided with sample pore, and the side of described thermal insulation cover is provided with refrigeration window, described refrigeration window and refrigeration module and seals cooperation;

Described incubation device includes incubation dish, conducting slip ring, rotary tray motor, heating plate, temperature sensor, incubation disc carrier, and described incubation dish is located on incubation disc carrier, and the back side of described incubation dish is provided with heating plate and temperature sensor; Described conducting slip ring is located at the wire of the center of incubation dish, heating plate and temperature sensor and is all wrapped on conducting slip ring; The axle that rotates of described rotary tray motor is connected with the center of incubation dish; The round edge of described incubation dish is provided with some reaction cup aperture;

Described Magneto separate assembly includes the motor that seesaws, promote device, magnet frame, Magnet, Magnet fixed block, Magneto separate support, Magneto separate base, spring assembly, described magnet frame is connected with the motor that seesaws by promoting device, magnet frame is provided with some magnetic receivers, described Magnet fixed block is located in magnetic receiver, described Magnet is located at the side simultaneously acting on reaction cup in Magnet fixed block close to bottom place, the described motor that seesaws, device and magnet frame is promoted all to be located on Magneto separate support, described Magneto separate props up and is set up on Magneto separate base, described spring assembly is located at inside magnetic receiver, and it is positioned at after Magnet fixed block,

Described measurement apparatus includes photomultiplier tube, renovate motor, renovate, measurement apparatus electric rotating machine, measuring chamber, strengthen liquid filler, described photomultiplier tube is connected with measuring chamber, described motor of renovating is connected with renovating by measurement apparatus connecting rod, it is provided with rotor inside described measuring chamber, rotor is provided with some reaction cup and places position, described rotor includes a primary response cup and places position and a detection reaction cup placement position, described primary response cup is placed position and is positioned at the underface of measuring chamber opening, described detection reaction cup is placed position and is positioned on the detecting position of measuring chamber, the described opening sealing cooperation with measuring chamber of renovating makes whole measuring chamber be internally formed sealing space, described measurement apparatus electric rotating machine is connected with rotor, described strengthens the top that liquid filler is arranged in the detecting position of measuring chamber.

3. a kind of Full-automatic chemiluminescence analyzer according to claims 1, it is characterised in that described refrigeration module includes air scoop, upper clamshell, lower clamshell, semiconductor chilling plate, radiator fan, chilled air fan, cool guide sheet, bracer and fin; Described upper clamshell is connected with lower clamshell; Described cool guide sheet is located at inside clamshell, and described fin is located at inside lower clamshell; Described block supports fin is in lower clamshell; Described air scoop is located at the air outlet place of chilled air fan and is connected with upper clamshell, forms a gas channel; Described semiconductor chilling plate is positioned in the middle of cool guide sheet and fin, and cool guide sheet is close to by the huyashi-chuuka (cold chinese-style noodles) of described semiconductor chilling plate, and its hot side is close to fin; Described cool guide sheet is connected with fin; Described chilled air fan is located at above cool guide sheet and is close on cool guide sheet; Described radiator fan is located at the lower section of fin and is close on a heat sink;

Described sampling needle assembly includes sampling needle, sampling needle support, sampling needle rotator, sampling needle electric rotating machine, sampling needle up and down motion motor, sampling needle base, sampling needle lifter, Magnet latch segment, described sampling needle lifter is located on sampling needle base, described Magnet latch segment is connected with the rotating shaft of sampling needle up and down motion motor, described rotating shaft is connected with sampling needle lifter, described sampling needle is located on sampling needle support, described sampling needle support and sampling needle rotator connect, described sampling needle rotator is connected with sampling needle electric rotating machine,

Described mixing component includes stirring paddle, stirring paddle support, stirring motor, stirring rotator, stirring electric rotating machine, stirring up and down motion motor, stirring base, stirring lifter, Magnet latch segment, described stirring lifter is located on stirring base, described Magnet latch segment is connected with the rotating shaft of stirring up and down motion motor, described rotating shaft is connected with stirring lifter, described stirring paddle is located on stirring paddle support, described stirring motor is connected with stirring paddle, described stirring paddle support and stirring rotator connect, described stirring rotator is connected with stirring electric rotating machine,

Described cleaning station assembly includes cleaning station support, splined shaft, combined type cleaning pin and cleaning station up and down motion motor, described cleaning station support includes support base plate, support riser, rack plate and support transverse slat, described support riser is located on support base plate, described rack plate is located at the top of support riser, described support riser is provided with cleaning guide rail and cleans slide block, described support transverse slat is located at the middle part of support riser and is fixed on cleaning slide block, described cleaning slide block is located on cleaning guide rail, described cleaning station up and down motion motor is located on support base plate, described splined shaft is connected through rack plate with support transverse slat, described combined type cleaning pin is located on splined shaft, the screw mandrel of described cleaning station up and down motion motor is connected through support transverse slat with the nut on rack plate.

4. a kind of Full-automatic chemiluminescence analyzer according to claims 2, it is characterized in that, described detecting device includes fixed block, optocoupler, spring, pin, catch, described fixed block is provided with chute, described pin is stopper, baffle plate and feeler lever from top to bottom successively, the top of described stopper is located in chute, described spring housing is between the bottom and baffle plate of stopper, described catch is fixed in stopper and between stopper and optocoupler, and described optocoupler is fixed on fixed block; Described jaw is made up of symmetrical jaw arm and jaws, and jaws is positioned at the end of jaw arm, and described jaws is curved; The lower end inside of described jaw arm is provided with groove;

Described evenly mixing device includes shaking up gear, electric rotating machine, shakes up motor, Timing Belt, connecting rod, central shaft, rotating shaft and eccentric, the top of central shaft is located at by the described gear that shakes up, described electric rotating machine is connected with the bottom of central shaft by Timing Belt, described eccentric is located at and is shaken up on motor, described eccentric is connected with the bottom of central shaft by connecting rod, and described rotating shaft is sheathed on the middle part of central shaft and is fixedly linked with reagent disc;

The described heating plate in incubation dish is affixed on the incubation dish back side by gluing; The bottom of described reaction cup aperture is additionally provided with small sircle hole, and described temperature sensor is fixed in the small sircle hole at the incubation dish back side; The outside of described reaction cup aperture is Openworks shape;

The described motor that seesaws is lead screw motor; Described promotion device includes Magneto separate line slideway and Magneto separate slide block, and described Magneto separate slide block is positioned on Magneto separate line slideway, and described Magneto separate slide block and the nut of lead screw motor are fixedly linked, and described Magneto separate slide block and magnet frame are fixedly linked; The last position of described magnet frame is low level Magnet fixed block, and the described Magnet in low level Magnet fixed block acts on the bottom of reaction cup;

Described measurement apparatus also includes measurement apparatus magnetic receiver, and described measurement apparatus magnetic receiver is located at the outside of measuring chamber, and the primary response cup of itself and rotor is placed position and is located along the same line;

Described rotor includes rotor Timing Belt and rotor synchronous pulley, and described rotor synchronous pulley is connected with the rotating shaft of measurement apparatus electric rotating machine, and rotor driven rotates the detecting position making the reaction cup on rotor arrive photomultiplier tube.

5. a kind of Full-automatic chemiluminescence analyzer according to claims 3, it is characterised in that described refrigeration module also includes heat-preservation cotton, and described heat-preservation cotton is between upper clamshell and lower clamshell; A described bracer is located at fin both sides, and the height of a described bracer is not higher than the contact surface of fin Yu semiconductor chilling plate;

Described refrigeration module also includes fixing seat, and described lower clamshell is connected with base plate by fixing seat, is fixed on base plate by refrigeration module;

Described sampling needle assembly is identical with the Magnet latch segment in mixing component, it includes two contrary annular magnets of magnetic, annular magnet is connected with the rotating shaft of sampling needle up and down motion motor or stirring up and down motion motor, and rotating shaft is connected with the synchronous pulley of sampling needle lifter or stirring lifter;

Described combined type cleaning pin includes cleaning needle shell fragment, cleans punch block, cleaning needle, cleaning needle guard, described cleaning needle is located in cleaning needle guard, described cleaning needle includes injection needle, aspirating needle, one end of described cleaning needle shell fragment is connected with the top cleaning needle guard, its other end is fixing with cleaning punch block to be connected, the syringe needle of described injection needle is connected with flexible pipe, and the syringe needle of described aspirating needle is connected with flexible pipe;

Described cleaning punch block is connected with splined shaft;

The described top cleaning needle guard is provided with draw-in groove, is used for blocking cleaning needle shell fragment.

6. a kind of Full-automatic chemiluminescence analyzer according to claims 2, it is characterised in that described X-axis guide assembly includes X-axis rail brackets, X-axis line slideway, X-axis Timing Belt, X-axis synchronizing wheel, X-axis slide block; Described X-axis line slideway is located on X-axis rail brackets, described X-axis slide block is located on X-axis line slideway, described X-axis Timing Belt and X-axis synchronizing wheel drive X-axis slide block to slidably reciprocate on X-axis line slideway, and the rotating shaft of described X-axis synchronizing wheel is connected with X-axis motor; Described Y-axis guide assembly includes Y-axis rail brackets, Y-axis line slideway, Y-axis Timing Belt, Y-axis synchronizing wheel, Y-axis slide block; Described Y-axis line slideway is located on Y-axis rail brackets, described Y-axis slide block is located on Y-axis line slideway, described Y-axis Timing Belt and Y-axis synchronizing wheel drive Y-axis slide block to slidably reciprocate on Y-axis line slideway, and the rotating shaft of described Y-axis synchronizing wheel is connected with y-axis motor; Described Z axis guide assembly includes Z axis polished rod, Z axis linear bearing, Z axis Timing Belt, Z axis synchronizing wheel, described Z axis linear bearing is located on Z axis polished rod, described Z axis Timing Belt and Z axis synchronizing wheel drive Z axis linear bearing to move up and down on Z axis polished rod, and the rotating shaft of described Z axis synchronizing wheel is connected with Z axis motor;

Described Y-axis rail brackets is located on X-axis slide block; Described Z axis polished rod is located on Y-axis slide block; Described mechanical gripper is located on Z axis linear bearing;

Described lucite lid is provided with thieff hatch and handle, plexiglass cover and thermal insulation cover and seals cooperation; Described thieff hatch is curved, matches with the putting position of reagent bottle;

Described reagent sample disk and incubation device also include drip tray, and described drip tray is positioned at the lower section of sample disk or incubation dish and is positioned at sample pore or the underface of reaction cup aperture;

Described magnet frame is in sector;

The described axle renovating motor is provided with eccentric, and described eccentric drives measurement apparatus connecting rod, being opened by what the control of measurement apparatus connecting rod was renovated and being closed.

7. a kind of Full-automatic chemiluminescence analyzer according to claims 3, it is characterised in that the described radiator fan in refrigeration module has two, the blade installation direction of two radiator fans is contrary, is provided with dividing plate between two radiator fans; Described dividing plate is fixed in lower clamshell, and its lower plane is equal with the bottom surface of lower clamshell, and upper plane connects with the tooth top of fin;

The end of described sampling needle is provided with flange copper sheet;

Described sampling needle lifter and stirring lifter all include Timing Belt, synchronous pulley and guide rail, and described synchronous pulley is connected with the rotating shaft of sampling needle up and down motion motor or stirring up and down motion motor; Described sampling needle rotator and stirring rotator all include Timing Belt, synchronous pulley, and described synchronous pulley is connected with the rotating shaft of sampling needle electric rotating machine or stirring electric rotating machine.

8. a kind of Full-automatic chemiluminescence analyzer according to claims 2 or 4 or 6, it is characterised in that the side of described thermal insulation cover is provided with detection mouth;

Described incubation dish adopts pure aluminum material;

Described Magneto separate support is provided with Magneto separate lifter and Magneto separate lifting motor.

9. a kind of Full-automatic chemiluminescence analyzer according to claim 3 or 5 or 7, it is characterised in that the upper clamshell in described refrigeration module is connected by screw with lower clamshell; Described cool guide sheet is connected with fin by plastic screw.

10. a kind of Full-automatic chemiluminescence analyzer according to claim 5, it is characterised in that described cleaning needle has at least; Described aspirating needle is longer than injection needle, and the syringe needle of injection needle bends to aspirating needle direction; Described cleaning needle shell fragment is spring steel plate.