CN105473153A - 包含具有减小的免疫原性的经修饰的噬菌体g3p氨基酸序列的多肽 - Google Patents
包含具有减小的免疫原性的经修饰的噬菌体g3p氨基酸序列的多肽 Download PDFInfo
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107250154A (zh) * | 2014-12-03 | 2017-10-13 | 普罗克拉拉生物科学股份有限公司 | 包含缺乏糖基化信号的经修饰的噬菌体g3p氨基酸序列的多肽 |
| CN107384960A (zh) * | 2017-07-25 | 2017-11-24 | 吉优诺(上海)基因科技有限公司 | 基于复制缺陷性重组腺病毒携带il‑17结合分子转基因载体及其构建方法和应用 |
| CN114057858A (zh) * | 2020-08-10 | 2022-02-18 | 北京太东生物科技有限公司 | 对引起神经变性和神经退行性疾病的蛋白聚集具有解聚作用的多肽 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2785364B1 (en) | 2011-11-29 | 2019-01-09 | Proclara Biosciences, Inc. | Use of p3 of bacteriophage as amyloid binding agents |
| MX358755B (es) | 2012-10-02 | 2018-09-03 | Proclara Biosciences Inc | Uso del p3 de proteinas de fusion de bacteriofago como agentes de union amiloides. |
| US11692017B2 (en) | 2018-06-15 | 2023-07-04 | Amyl Therapeutics Srl | General amyloid interaction motif (GAIM) |
| EP3966227A1 (en) | 2019-05-07 | 2022-03-16 | Voyager Therapeutics, Inc. | Compositions and methods for the vectored augmentation of protein destruction, expression and/or regulation |
| BR112023001238A2 (pt) | 2020-07-24 | 2023-04-04 | Jawaharlal Nehru Centre For Advanced Scient Research | Compostos de monoimida de naftaleno e métodos para os mesmos |
| KR20250110352A (ko) | 2022-12-02 | 2025-07-18 | 알제온, 인크. | 트라미프로세이트를 이용하여 신경퇴행성 장애를 치료하는 방법 |
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| MX358755B (es) * | 2012-10-02 | 2018-09-03 | Proclara Biosciences Inc | Uso del p3 de proteinas de fusion de bacteriofago como agentes de union amiloides. |
| SG11201704427YA (en) | 2014-12-03 | 2017-06-29 | Proclara Biosciences Inc | Polypeptides comprising a modified bacteriophage g3p amino acid sequence lacking a gylcosylation signal |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101166536A (zh) * | 2005-02-01 | 2008-04-23 | 雷蒙特亚特特拉维夫大学有限公司 | 治疗与淀粉样蛋白沉积有关的炎症和涉及已活化小胶质细胞的脑部炎症的方法 |
| WO2011084714A2 (en) * | 2009-12-17 | 2011-07-14 | Biogen Idec Ma Inc. | STABILIZED ANTI-TNF-ALPHA scFv MOLECULES OR ANTI-TWEAK scFv MOLECULES AND USES THEREOF |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107250154A (zh) * | 2014-12-03 | 2017-10-13 | 普罗克拉拉生物科学股份有限公司 | 包含缺乏糖基化信号的经修饰的噬菌体g3p氨基酸序列的多肽 |
| CN107384960A (zh) * | 2017-07-25 | 2017-11-24 | 吉优诺(上海)基因科技有限公司 | 基于复制缺陷性重组腺病毒携带il‑17结合分子转基因载体及其构建方法和应用 |
| CN107384960B (zh) * | 2017-07-25 | 2020-06-12 | 吉优诺(上海)基因科技有限公司 | 基于复制缺陷性重组腺病毒携带il-17结合分子转基因载体及其构建方法和应用 |
| CN114057858A (zh) * | 2020-08-10 | 2022-02-18 | 北京太东生物科技有限公司 | 对引起神经变性和神经退行性疾病的蛋白聚集具有解聚作用的多肽 |
| US11970517B2 (en) | 2020-08-10 | 2024-04-30 | Rejukon Biopharm Inc. | Compositions and methods for dissolving protein aggregates |
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| US20160115223A1 (en) | 2016-04-28 |
| AU2014274253A1 (en) | 2016-01-21 |
| JP2016526044A (ja) | 2016-09-01 |
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| US9988444B2 (en) | 2018-06-05 |
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| EP3003349A1 (en) | 2016-04-13 |
| EA201592272A1 (ru) | 2016-04-29 |
| AU2014274253B2 (en) | 2018-06-14 |
| US20170129945A9 (en) | 2017-05-11 |
| MX2015016263A (es) | 2016-04-18 |
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| KR20160010618A (ko) | 2016-01-27 |
| PH12015502585A1 (en) | 2016-02-29 |
| SG11201509647WA (en) | 2015-12-30 |
| US20180251534A1 (en) | 2018-09-06 |
| EA030389B1 (ru) | 2018-07-31 |
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