CN105473153A - 包含具有减小的免疫原性的经修饰的噬菌体g3p氨基酸序列的多肽 - Google Patents

包含具有减小的免疫原性的经修饰的噬菌体g3p氨基酸序列的多肽 Download PDF

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Publication number
CN105473153A
CN105473153A CN201480030678.2A CN201480030678A CN105473153A CN 105473153 A CN105473153 A CN 105473153A CN 201480030678 A CN201480030678 A CN 201480030678A CN 105473153 A CN105473153 A CN 105473153A
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seq
amino acid
none
polypeptide
disease
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Chinese (zh)
Inventor
F.J.卡尔
T.D.琼斯
R.A.费希尔
R.G.E.霍尔盖特
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Proclara Biosciences Inc
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NeuroPhage Pharmaceuticals Inc
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    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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CN201480030678.2A 2013-05-28 2014-05-28 包含具有减小的免疫原性的经修饰的噬菌体g3p氨基酸序列的多肽 Pending CN105473153A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361828004P 2013-05-28 2013-05-28
US61/828,004 2013-05-28
US201361828497P 2013-05-29 2013-05-29
US61/828,497 2013-05-29
PCT/US2014/039760 WO2014193935A1 (en) 2013-05-28 2014-05-28 Polypeptides comprising a modified bacteriophage g3p amino acid sequence with reduced immunogenicity

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CN105473153A true CN105473153A (zh) 2016-04-06

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CN201480030678.2A Pending CN105473153A (zh) 2013-05-28 2014-05-28 包含具有减小的免疫原性的经修饰的噬菌体g3p氨基酸序列的多肽

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US (2) US9988444B2 (enExample)
EP (1) EP3003349B1 (enExample)
JP (1) JP2016526044A (enExample)
KR (1) KR20160010618A (enExample)
CN (1) CN105473153A (enExample)
AU (1) AU2014274253B2 (enExample)
CA (1) CA2913414A1 (enExample)
EA (1) EA030389B1 (enExample)
HK (1) HK1223285A1 (enExample)
MX (1) MX2015016263A (enExample)
PH (1) PH12015502585A1 (enExample)
SG (1) SG11201509647WA (enExample)
WO (1) WO2014193935A1 (enExample)

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CN107250154A (zh) * 2014-12-03 2017-10-13 普罗克拉拉生物科学股份有限公司 包含缺乏糖基化信号的经修饰的噬菌体g3p氨基酸序列的多肽
CN107384960A (zh) * 2017-07-25 2017-11-24 吉优诺(上海)基因科技有限公司 基于复制缺陷性重组腺病毒携带il‑17结合分子转基因载体及其构建方法和应用
CN114057858A (zh) * 2020-08-10 2022-02-18 北京太东生物科技有限公司 对引起神经变性和神经退行性疾病的蛋白聚集具有解聚作用的多肽

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EP2785364B1 (en) 2011-11-29 2019-01-09 Proclara Biosciences, Inc. Use of p3 of bacteriophage as amyloid binding agents
MX358755B (es) 2012-10-02 2018-09-03 Proclara Biosciences Inc Uso del p3 de proteinas de fusion de bacteriofago como agentes de union amiloides.
US11692017B2 (en) 2018-06-15 2023-07-04 Amyl Therapeutics Srl General amyloid interaction motif (GAIM)
EP3966227A1 (en) 2019-05-07 2022-03-16 Voyager Therapeutics, Inc. Compositions and methods for the vectored augmentation of protein destruction, expression and/or regulation
BR112023001238A2 (pt) 2020-07-24 2023-04-04 Jawaharlal Nehru Centre For Advanced Scient Research Compostos de monoimida de naftaleno e métodos para os mesmos
KR20250110352A (ko) 2022-12-02 2025-07-18 알제온, 인크. 트라미프로세이트를 이용하여 신경퇴행성 장애를 치료하는 방법

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CN107250154A (zh) * 2014-12-03 2017-10-13 普罗克拉拉生物科学股份有限公司 包含缺乏糖基化信号的经修饰的噬菌体g3p氨基酸序列的多肽
CN107384960A (zh) * 2017-07-25 2017-11-24 吉优诺(上海)基因科技有限公司 基于复制缺陷性重组腺病毒携带il‑17结合分子转基因载体及其构建方法和应用
CN107384960B (zh) * 2017-07-25 2020-06-12 吉优诺(上海)基因科技有限公司 基于复制缺陷性重组腺病毒携带il-17结合分子转基因载体及其构建方法和应用
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US20160115223A1 (en) 2016-04-28
AU2014274253A1 (en) 2016-01-21
JP2016526044A (ja) 2016-09-01
EP3003349B1 (en) 2018-12-12
US9988444B2 (en) 2018-06-05
CA2913414A1 (en) 2014-12-04
EP3003349A1 (en) 2016-04-13
EA201592272A1 (ru) 2016-04-29
AU2014274253B2 (en) 2018-06-14
US20170129945A9 (en) 2017-05-11
MX2015016263A (es) 2016-04-18
HK1223285A1 (zh) 2017-07-28
WO2014193935A1 (en) 2014-12-04
KR20160010618A (ko) 2016-01-27
PH12015502585A1 (en) 2016-02-29
SG11201509647WA (en) 2015-12-30
US20180251534A1 (en) 2018-09-06
EA030389B1 (ru) 2018-07-31

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