CN105434636A - Traditional Chinese medicine composition used for treating duckling hepatitis, and preparation method thereof - Google Patents
Traditional Chinese medicine composition used for treating duckling hepatitis, and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention relates to a traditional Chinese medicine composition used for treating duckling hepatitis. The traditional Chinese medicine composition is prepared from poria cocos, herba artemisiae scopariae, all-grass of madras grangea, fructus schisandrae chinensis, peach kernel, and lucid ganoderma. The traditional Chinese medicine composition can be made into powder. A preparation method comprises following steps: (1) 16 to 26 parts of poria cocos, 16 to 24 parts of herba artemisiae scopariae, 12 to 20 parts of all-grass of madras grangea, 10 to 18 parts of fructus schisandrae chinensis, 10 to 20 parts of peach kernel, and 10 to 18 parts of lucid ganoderma are weighed; (2) the ingredients above are smashed, and are sieved using a sieve of 40 to 100 meshes; (3) a traditional Chinese medicine powder is obtained via 5 to 15min of mixing; and (4) the traditional Chinese powder is subjected to subpackage so as to obtain finished products, wherein each bag contains 100 to 300g. The traditional Chinese medicine composition is prepared from pure natural Chinese herbal medicines, is capable of inducing diuresis to alleviate edema, disinhibiting dampness and relieving jaundice, relieving diarrhea with astringents, activating blood circulation to remove blood stasis, and invigorating qi and calming the nerves, can be used for treating duckling hepatitis effectively; and cure rate is as high as 92.83%.
Description
Technical field
The invention belongs to Chinese veterinary drug preparation field, especially a kind ofly treat Chinese medicine composition of duckling hepatitis and preparation method thereof.
Background technology
Duckling hepatitis causes the one of duckling to propagate rapid, height lethal infectious diseases by DHV.Principal character is liver enlargement, has hemorrhage speckle and nervous symptoms.
Primary disease mainly betides 4 ~ 20 age in days ducklings, and adult duck has resistance.Sick duck and the malicious duck of band are major source of infection, mainly through digestive tract and respiratory tract infection.Primary disease betides the season of hatching duckling, once occur, bamboo telegraph in duckling group, sickness rate can reach 100%.Children duck mostly is sudden onset, and disease just shows as lethargy, necking down hogback, the soft astasia of foot, and peel off, eyes are narrowed, and show as somnolence state.Part sick duck row dish green or white liquid loose stool.Soon namely occur nervous symptoms after morbidity, uneasy, movement disorder, health swings to side, bipod generation spasm, and after there is nervous symptoms, a few hours are namely dead.Dead front to palintrope, in opisthotonus posture.The mortality rate of primary disease is variant because of the age, and the duckling within 1 week age can up to 95%, the duckling about 50% in 1 ~ 3 week age, and the young duck in 4 ~ 5 week age is substantially not dead.Dissect visible features sexually transmitted disease (STD) to become at liver, liver enlargement, easily tears, and matter is crisp, and in khaki, isabelline, yellow-white, there is the darkviolet petechia differed in size on surface, plaque-like striped or necrosis region.Gollbladder dilation, bile is thin.Spleen, kidney also have enlargement in various degree, hyperemia, hemorrhage.Cephalemia, edema.
At present, China only finds duck hepatitis I type virus, and treatment duckling hepatitis is taked to treat morbidity duckling group injection standard DVH-1 high immunity yolk antibody more.But discovered in recent years primary disease occurs more serious popular in certain areas, its epidemic situation can not be controlled completely by standard duck viral hepatitis I type attenuated vaccine, I type virulent duck enteritis virus variant may be had to occur.Treatment by Chinese herbs duckling hepatitis is treating both the principal and secondary aspects of a disease, effectively can avoid virus variation, thus controls epidemic situation, prevents the further infection of disease, reduces economic loss.Therefore in the urgent need to developing the Chinese medicine preparation effectively can treating duckling hepatitis.
Summary of the invention
The problem to be solved in the present invention is: overcome the deficiencies in the prior art, provides a kind of evident in efficacy, Chinese medicine composition that cure rate is high.
Another technical problem that the present invention will solve is: provide a kind of Chinese medicine formula for the treatment of duckling hepatitis.
Another technical problem that the present invention will solve is: the preparation method providing the powder of above-mentioned Chinese medicine composition.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of duckling hepatitis, is characterized in that: be prepared from by the raw material of following mass fraction: Poria 16-26 part, Herba Artemisiae Scopariae 16-24 part, Herba Hyperici Japonici 12-20 part, Fructus Schisandrae Chinensis 10-18 part, Semen Persicae 10-20 part, Ganoderma 10-18 part.
Further, the mass fraction of the optimum feed stock of this Chinese medicine composition is as follows: 24 parts, Poria, Herba Artemisiae Scopariae 18 parts, Herba Hyperici Japonici 16 parts, Fructus Schisandrae Chinensis 12 parts, 16 parts, Semen Persicae, Ganoderma 14 parts.
Further, this Chinese medicine composition is the various conventional extract oral medicine dosage form containing or do not contain pharmaceutic adjuvant.
Further, described preparation can be powder.
Further, the preparation method of the powder of said composition is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine was pulverized 40-100 mesh sieve; (3) mix 5-15 minute and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 100-300g subpackage, get product.
The advantage that the present invention has and good effect are:
(1) this prescription is according to tcm theory, and scientific compatibility, has effect of inducing diuresis to remove edema, dampness removing jaundice eliminating, relieving diarrhea with astringents, blood circulation promoting and blood stasis dispelling, invigorating QI and tranquilization.Through Clinical Laboratory treatment duckling hepatitis determined curative effect, cure rate can reach 92.83%.
(2) this prescription selects pure natural Chinese herbal medicine to be raw material, has no side effect, pollution-free, is a kind of green veterinary drug really.
(3) pharmacological action of each raw material of Chinese medicine of the present invention is:
Poria: promoting diuresis to eliminate damp pathogen, invigorating the spleen to arrest diarrhea;
Herba Artemisiae Scopariae: eliminating damp-heat, promoting the function of the gallbladder to alleviate jaundice;
Herba Hyperici Japonici: dampness removing jaundice eliminating, heat-clearing and toxic substances removing, promoting blood circulation and detumescence;
Fructus Schisandrae Chinensis: restrain astringent or styptic treatment for spontaneous sweating;
Semen Persicae: blood circulation promoting and blood stasis dispelling;
Ganoderma: invigorating QI and tranquilization.
Among formula, Poria sweet in the mouth and light, Gan Zeneng mends, light, can ooze, mild in medicine property and, diuretic and do not hinder healthy energy, is the key medicine of inducing diuresis to remove edema, can controls the various edema of cold and heat and asthenia and sthenia.Poria can also spleen invigorating eliminating dampness by diuresis and antidiarrheal, is especially suitable for insufficiency of the spleen leading to overabundance of dampness to be had loose bowels.The bitter diarrhea of Herba Artemisiae Scopariae falls, heat clearing away cold in nature, and kind clear sharp taste dampness-heat in the liver and gallbladder, making it to go out from urine, is the key medicine of subcutaneous ulcer of harnessing the Yellow River.Herba Artemisiae Scopariae and Poria are arranged in pairs or groups and can be harnessed the Yellow River subcutaneous ulcer weight in wet base in heat.Herba Hyperici Japonici has another name called Herba Hyperici Japonici, and its property hardship is cool, enters liver and gall warp, can clearing heat, detoxicating, dispelling dampness and jaundice eliminating subcutaneous ulcer, with controlling jaundice due to damp-heat.Fructus Schisandrae Chinensis sour in the mouth adstringency is restrained, and energy relieving diarrhea with astringents, controls spleen-kidney vacuity cold incessant chronic diarrhea.Semen Persicae bitter in the mouth, enters conscience blood system, is apt to rush down stasis, and blood stasis dispelling power is strong, also known as stasis-breaking drug, for treating the common medicine of multiple congestion retardance disease.Ganoderma sweet in the mouth is put down, and has the effect of benefiting qi and nourishing blood, can control the diseases such as asthenia is breathed hard, the tired Mental fatigue of body, anorexia.
Above-mentioned Six-element medicine compatibility uses, and has effect of inducing diuresis to remove edema, dampness removing jaundice eliminating, relieving diarrhea with astringents, blood circulation promoting and blood stasis dispelling, invigorating QI and tranquilization, can effectively treat duckling hepatitis.
Detailed description of the invention
Be further described the present invention below by specific embodiment, following examples are descriptive, are not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
Treat a Chinese powder medicine for duckling hepatitis, the parts by weight of each raw material are as follows: 24 parts, Poria, Herba Artemisiae Scopariae 18 parts, Herba Hyperici Japonici 16 parts, Fructus Schisandrae Chinensis 12 parts, 16 parts, Semen Persicae, Ganoderma 14 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by above-mentioned formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mixing obtains Chinese medicine for 10 minutes and mixes powder; (4) Chinese medicine is mixed powder by every bag of 200g subpackage, get product.
Embodiment 2
Treat a Chinese powder medicine for duckling hepatitis, the parts by weight of each raw material are as follows: 20 parts, Poria, Herba Artemisiae Scopariae 24 parts, Herba Hyperici Japonici 18 parts, Fructus Schisandrae Chinensis 16 parts, 12 parts, Semen Persicae, Ganoderma 10 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by above-mentioned formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mixing obtains Chinese medicine for 10 minutes and mixes powder; (4) Chinese medicine is mixed powder by every bag of 200g subpackage, get product.
Embodiment 3
Treat a Chinese powder medicine for duckling hepatitis, the parts by weight of each raw material are as follows: 18 parts, Poria, Herba Artemisiae Scopariae 16 parts, Herba Hyperici Japonici 14 parts, Fructus Schisandrae Chinensis 18 parts, 18 parts, Semen Persicae, Ganoderma 16 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by above-mentioned formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mixing obtains Chinese medicine for 10 minutes and mixes powder; (4) Chinese medicine is mixed powder by every bag of 200g subpackage, get product.
Embodiment 4
Treat a Chinese powder medicine for duckling hepatitis, the parts by weight of each raw material are as follows: 16 parts, Poria, Herba Artemisiae Scopariae 20 parts, Herba Hyperici Japonici 12 parts, Fructus Schisandrae Chinensis 14 parts, 20 parts, Semen Persicae, Ganoderma 18 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by above-mentioned formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mixing obtains Chinese medicine for 10 minutes and mixes powder; (4) Chinese medicine is mixed powder by every bag of 200g subpackage, get product.
Embodiment 5
Treat a Chinese powder medicine for duckling hepatitis, the parts by weight of each raw material are as follows: 26 parts, Poria, Herba Artemisiae Scopariae 22 parts, Herba Hyperici Japonici 20 parts, Fructus Schisandrae Chinensis 10 parts, 10 parts, Semen Persicae, Ganoderma 12 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by above-mentioned formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mixing obtains Chinese medicine for 10 minutes and mixes powder; (4) Chinese medicine is mixed powder by every bag of 200g subpackage, get product.
Clinical trial
Experiment 1:
Huludao Liaoning Province one raise ducks specialized household has raised the Cherry Village Ducks about more than 600 15 ages in days.Part duckling sudden onset, cashes as lassitude, head and neck is rolled up, two wings are sagging, is slow in action, and what have peels off, lies prostrate in a colony house a corner, have dull, stand reluctantly, two semi-closures, what have squats down, dozes off, and draws yellow-white, celadon loose stool.Get two sick ducks and cut open inspection, find that its specific lesions all occurs in liver, liver enlargement, fragile, color and luster is dim, slightly yellow, and there is hemorrhage speckle on surface, adularescent necrosis region.Gallbladder fills, and enlargement, bile is light green.A wherein sick duck splenomegaly, outward appearance is mottling.The sick duck kidney of another is slightly swollen, and other organs have no obvious naked eyes pathological changes.According to its incidence, clinical symptoms with cut open inspection result, be tentatively judged as duckling hepatitis.Then by more than 30 sick duck isolated rearing of morbidity, the Chinese powder medicine and spice is fed obtained by the embodiment of the present invention 1 is treated, and spice ratio is 200g Chinese powder medicine: 150Kg feedstuff, one day 2 times, is used in conjunction 7 days.All the other duckling injection standard duck viral hepatitis attenuated vaccines of not falling ill prevent.Medication is after 2 days, and except 2 sick ducks are because of except state of an illness Serious Mortality, the spirit of all the other sick ducks starts to take a turn for the better, and just number of times of having loose bowels obviously reduces.Continue medication after 5 days, sick duck spirit is recovered completely, normal activity, and the frequency of defecation and form all recover normal, and jumpbogroup is fully recovered.
Test 1 result to show, the Chinese powder medicine treatment duckling hepatitis obtained by patent Example 1 of the present invention can obtain good curative effect, effectively can control the further propagation of disease, reduce the economic loss of raiser.
Experiment 2
Jiangsu Province's Taizhou City one supports the sheldrake that 2000 1 ~ 3 week ages have been raised in goose field.Part sheldrake sudden onset, shows as down in spirits, dozes off, stand transfixed to the ground, loss of appetite, and some appearance diarrhoea, draws canescence or yellow green watery stools.The next day namely have more than 10 sick duck to occur nervous symptoms, fall and swing to side, play after two lower limbs are spastic, whole body is twitched, namely dead after a few hours.Dead front to palintrope, in opisthotonus posture.All dissected by 11 ducks that die of illness, find that major lesions is all at liver, shows as hepatomegaly, has point-like or stasis of blood ecchymosis, liver lighter, in yellowish red color, surface is in mottling, fragile, the downright bad point of adularescent tip-like.Splenomegaly has mottling hemorrhage.Gollbladder dilation.Most visible renomegaly.According to epidemiology, clinical symptoms with cut open inspection result, be tentatively judged as duckling hepatitis.Morbidity duckling and healthy duckling are strictly isolated.With standard DVH-1 high immunity yolk antibody cervical region subcutaneous injection (1.5ml/ only), the state of an illness is not effectively controlled, and has every day more than 10 sick duck dead.Suspection may be occurred I type DHV variant, then uses Chinese medicine instead and treats.Spice Chinese powder medicine obtained by the embodiment of the present invention 1 of feeding is treated, and spice is than being 200g Chinese powder medicine: 150Kg feedstuff, one day 2 times, is used in conjunction 7 days.Treat the 2nd day, the dead quantity of sick duck is just reduced to 4.From the 3rd day, no longer include death, sick duck spirit takes a turn for the better, and appetite starts to recover, and just number of times of having loose bowels reduces.To the 7th day, sick duck spirit was recovered completely, and freely, appetite is normal, and defecation frequency and form all return to normal in activity.Adopt the sick duck for the treatment of by Chinese herbs to amount to 223, dead 16, jumpbogroup is fully recovered, and cure rate is 92.83%.
Test 2 results to show, for having occurred I type DHV variant, subcutaneous injection standard DVH-1 high immunity yolk antibody carries out treating the situation that can not obtain curative effect, use the Chinese powder medicine obtained by the embodiment of the present invention 1 but can obtain preferably curative effect, effective symptom management, reduces mortality rate.Therefore, Chinese powder medicine of the present invention be adapted at clinical do further genralrlization use.
The above, be only preferred embodiments of the present invention, is illustrative instead of determinate, can list several embodiments according to limited range, therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (5)
1. treat a Chinese medicine composition for duckling hepatitis, it is characterized in that, be prepared from by the raw material of following mass fraction:
Poria 16-26 part, Herba Artemisiae Scopariae 16-24 part, Herba Hyperici Japonici 12-20 part, Fructus Schisandrae Chinensis 10-18 part, Semen Persicae 10-20 part, Ganoderma 10-18 part.
2. a kind of Chinese medicine composition for the treatment of duckling hepatitis according to claim 1, is characterized in that: the mass fraction of optimum feed stock is as follows:
24 parts, Poria, Herba Artemisiae Scopariae 18 parts, Herba Hyperici Japonici 16 parts, Fructus Schisandrae Chinensis 12 parts, 16 parts, Semen Persicae, Ganoderma 14 parts.
3. a kind of Chinese medicine composition for the treatment of duckling hepatitis according to claim 1 and 2, is characterized in that: this Chinese medicine composition is the various conventional extract oral medicine dosage form containing or do not contain pharmaceutic adjuvant.
4. a kind of Chinese medicine composition for the treatment of duckling hepatitis according to claim 3, is characterized in that: described preparation can be powder.
5. prepare an a kind of method for the treatment of the Chinese powder medicine of duckling hepatitis as claimed in claim 4, it is characterized in that, preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine was pulverized 40-100 mesh sieve; (3) mix 5-15 minute and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 100-300g subpackage, get product.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109303904A (en) * | 2017-07-29 | 2019-02-05 | 格特生物制药（天津）有限公司 | A kind of Chinese medicine composition and preparation method thereof for treating duck flower hepatopathy |
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| CN1720965A (en) * | 2005-05-29 | 2006-01-18 | 王福山 | Chinese medicinal composition for treating acute icterohepatitis |
| CN101274028A (en) * | 2007-03-26 | 2008-10-01 | 林宪秋 | Liver health care composition and preparation thereof |
| CN104547764A (en) * | 2014-12-20 | 2015-04-29 | 何庆军 | Medicine for recovering liver functions and preparation method thereof |
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- 2015-12-21 CN CN201510961661.5A patent/CN105434636A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1720965A (en) * | 2005-05-29 | 2006-01-18 | 王福山 | Chinese medicinal composition for treating acute icterohepatitis |
| CN101274028A (en) * | 2007-03-26 | 2008-10-01 | 林宪秋 | Liver health care composition and preparation thereof |
| CN104547764A (en) * | 2014-12-20 | 2015-04-29 | 何庆军 | Medicine for recovering liver functions and preparation method thereof |
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| 郑继芳: "《兽医中药学》", 31 December 2012, 金盾出版社 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109303904A (en) * | 2017-07-29 | 2019-02-05 | 格特生物制药（天津）有限公司 | A kind of Chinese medicine composition and preparation method thereof for treating duck flower hepatopathy |
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Application publication date: 20160330 |