CN104222632B - Feed for preventing coccidiosis of rabbits - Google Patents

Feed for preventing coccidiosis of rabbits Download PDF

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CN104222632B
CN104222632B CN201410459522.8A CN201410459522A CN104222632B CN 104222632 B CN104222632 B CN 104222632B CN 201410459522 A CN201410459522 A CN 201410459522A CN 104222632 B CN104222632 B CN 104222632B
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radix
rhizoma
feedstuff
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herba
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不公告发明人
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Interflavor Guangdong Biotechnology Co ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
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    • Y02P60/87Re-use of by-products of food processing for fodder production

Abstract

The invention provides a feed for preventing coccidiosis of rabbits. The feed comprises medicinal powder for treating the coccidiosis of the rabbits, corn, rice chaff, bean pulp, wheat bran, fish meal, bone powder and edible salt. The feed can relieve bleeding and diarrhea which are caused by the coccidiosis and achieve the effects of enhancing the organ immunity and the like so as to achieve the effect of treating both symptoms and root causes; the medicament does not have toxic and side effects, can delay the drug resistance, does not have medicament residues and is a good choice for preventing the coccidiosis.

Description

For preventing the feedstuff of rabbit coccidiosis
Technical field
The present invention relates to field of feed additive technology, more particularly, to a kind of medicine for preventing rabbit coccidiosis.
Background technology
Rabbit coccidiosis is to parasitize Hepar Leporis seu Oryctolagi bile duct and enterocyte by multiple coccidiosiss of Eimeria, and cause internal Parasitic disease.Coccidiosis are a kind of harm 30~70 age in days children rabbit parasites disease in the bodies the most serious.The coccidium infection of young rabbit Rate is 90%, and mortality rate is 60%.The sick rabbit initial stage shows as loss of appetite, does not like activity, and two dull, and at eye nose, secretions increase Many, anemia, dysentery, become thin, sometimes suffer from diarrhoea or diarrhoea is alternately present with constipation, growth retardation.When seriously ill, suffer from rabbit and fall down suddenly, Muscle spasm, hind leg is tetanic, and forelimb makees imperious stroke, and head, to layback, utters a heartrending cry sound and dead.The distribution of this disease is wide, biography Broadcast fast, mortality rate height, to the rabbit of different cultivars, all there is susceptibility, bring huge economic loss to rabbit keeping.Resistance to ball excessively Parasitosis is dead, or rabbit through curing becomes long-term parasite carrier, and becomes this sick source of infection.
Not yet develop rabbit coccidial vaccine at present, the main method of preventing and treating rabbit coccidiosis remains application anticoccidial both at home and abroad Medicine.In feedstuff add coccidiostat, be at present prevent rabbit coccidiosis major measure, for coccidiosis medicine very Many, from earliest sulfa drugss to Salinomycin and Maduramicin plasma carrier class medicine, it is complete, but these Anticoccidial drug all has more or less defect, and some drug toxicitys are big, and safety range is little, and some easily produce drug resistance, Application time too short some can not use with other medicines simultaneously, numerous anticoccidial drug on the market, raiser is often not Know and arranged, blindly apply, frequent dressing, lead to coccidiosis obstinate.From the end of the year 2008, in France, Italy and Spain Diclazuril has authorized rabbit feed addictive, however, the coccidiostat to develop according to Eimeria species pattern, have to rabbit ball Worm is simultaneously inoperative.It is usually used in preventing the active drug of rabbit coccidiosis to have Robenidine, diclazuril and Salinomycin;Medicine has Sulfa drugss and Toltrazuril.
Rabbit coccidiosis belongs to the category of malnutrition due to parasitic infestation in Chinese veterinarian, should can reach preventing and treating coccidiosis with heat-clearing and toxic substances removing, parasite killing medical herbs Effect, improve the resistances against diseases of ill chicken by improving the medicine of immunity of organisms meanwhile, especially reticuloendothelial Function, delays Drug resistance to produce.Rabbit coccidiosis is prevented using Chinese herbal medicine, is on the one hand the growth of suppression coccidiosiss, is on the other hand By adjusting the resistance function of animal body, breed generation nonspecific resistance to strengthen body's resistance to disease, reach and eliminate Pathogen and slow down its damage for cell, recovers the purpose of the normal physiological function of body.
Chinese herbal medicine mostly is natural plants, uses herbal control coccidiosis, both can reach the purpose of preventing and treating coccidiosis, has overcome again Frequent application anticoccidial drug and the residue of veterinary drug drawback brought, and it is not likely to produce drug resistance, do not cause environmental pollution.This The Chinese herbal medicine of bright offer passes through parasite killing anthelmintic, bangle removing toxic substances, cooling blood for hemostasis, improves immunity of organisms, can alleviate because of ball The effect such as bleeding that parasitosis leads to, dysentery, and enhancing body resistance, reaches effect for the treatment of both the principal and secondary aspects of a disease.
Content of the invention
The technical problem to be solved is to provide a kind of medicine for preventing rabbit coccidiosis and feedstuff, using raising Material can alleviate the effect such as bleeding because coccidiosis lead to, dysentery, and enhancing body resistance, reaches effect for the treatment of both the principal and secondary aspects of a disease, And this medicine has no toxic side effect, delays drug resistance, drug residue free, it is that prevention coccidiosis select well.
For solving above-mentioned technical problem, the present invention provides a kind of feedstuff for preventing rabbit coccidiosis, and it is included for pre- The drug powder of anti-rabbit coccidiosis, Semen Maydiss, rice chaff, bean cake, Testa Tritici, fish flour, bone meal and Sal.
Wherein, in described feedstuff each raw material weight be respectively drug powder 0.8kg~1.2kg, Semen Maydiss 45kg~55kg, Rice chaff 27kg~33kg, bean cake 12kg~18kg, Testa Tritici 8kg~12kg, fish flour 2kg~4kg, bone meal 1kg~3kg, Sal 0.5kg~1.5kg.
Wherein, in described feedstuff, the weight of each raw material is respectively drug powder 1kg, Semen Maydiss 50kg, rice chaff 20kg, bean cake 15kg, Testa Tritici 10kg, fish flour 3kg, bone meal 2kg, Sal 1kg.
Wherein, the crude drug of described drug powder include the Radix Pulsatillae, Radix Sanguisorbae, Flos Lonicerae, Radix Glycyrrhizae, Lignum Sappan, Rhizoma Curcumae, Cortex Magnoliae Officinalis, Herba Centipedae, Herba Artemisiae Annuae, Resina Ferulae, Gaultheria, Herba Stellariae Alsiness, Conyza japonica, Caulis Sargentodoxae, the Radix Stemonae, storage, Rhizoma Coptidis, Cortex Ailanthi, Bulbus Allii, buy fiber crops Rattan, Fructus Choerospondiatis, Folium Ginseng, Semen Myristicae, Rhizoma Et Radix Notopterygii, Folium Isatidiss and Concretio silicea Bambusae seu schizostachyi.
Wherein, in described medicine, the weight of each raw material is respectively Radix Pulsatillae 15g~25g, Radix Sanguisorbae 15g~25g, Flos Lonicerae 35g~45g, Radix Glycyrrhizae 15g~25g, Lignum Sappan 15g~25g, Rhizoma Curcumae 5g~15g, Cortex Magnoliae Officinalis 5g~15g, Herba Centipedae 5g~15g, green grass or young crops Artemisia 15g~25g, Resina Ferulae 5g~15g, Gaultheria 15g~25g, Herba Stellariae Alsiness 5g~15g, Conyza japonica 5g~15g, Caulis Sargentodoxae 5g~ 15g, Radix Stemonae 15g~25g, storage 15g~25g, Rhizoma Coptidis 35g~45g, Cortex Ailanthi 15g~25g, Bulbus Allii 15g~25g, Caulis Gneti 15g~25g, Fructus Choerospondiatis 15g~25g, Folium Ginseng 15g~25g, Semen Myristicae 15g~25g, Rhizoma Et Radix Notopterygii 5g~15g, Folium Isatidiss 25g~ 35g and Concretio silicea Bambusae seu schizostachyi 5g~15g.
Wherein, in described medicine, the weight of each raw material is respectively Radix Pulsatillae 18g~22g, Radix Sanguisorbae 18g~22g, Flos Lonicerae 38g~42g, Radix Glycyrrhizae 18g~22g, Lignum Sappan 18g~22g, Rhizoma Curcumae 8g~12g, Cortex Magnoliae Officinalis 8g~12g, Herba Centipedae 8g~12g, green grass or young crops Artemisia 18g~22g, Resina Ferulae 8g~12g, Gaultheria 18g~22g, Herba Stellariae Alsiness 8g~12g, Conyza japonica 8g~12g, Caulis Sargentodoxae 8g~ 12g, Radix Stemonae 18g~22g, storage 18g~22g, Rhizoma Coptidis 38g~42g, Cortex Ailanthi 18g~22g, Bulbus Allii 18g~22g, Caulis Gneti 18g~22g, Fructus Choerospondiatis 18g~22g, Folium Ginseng 18g~22g, Semen Myristicae 18g~22g, Rhizoma Et Radix Notopterygii 8g~12g, Folium Isatidiss 28g~ 32g and Concretio silicea Bambusae seu schizostachyi 8g~12g.
Wherein, in described medicine each raw material weight be respectively Radix Pulsatillae 20g, Radix Sanguisorbae 20g, Flos Lonicerae 40g, Radix Glycyrrhizae 20g, Lignum Sappan 20g, Rhizoma Curcumae 10g, Cortex Magnoliae Officinalis 10g, Herba Centipedae 10g, Herba Artemisiae Annuae 20g, Resina Ferulae 10g, Gaultheria 20g, Herba Stellariae Alsiness 10g, Chinese liquor Careless 10g, Caulis Sargentodoxae 10g, Radix Stemonae 20g, store 20g, Rhizoma Coptidis 40g, Cortex Ailanthi 20g, Bulbus Allii 20g, Caulis Gneti 20g, Fructus Choerospondiatis 20g, Folium Ginseng 20g, Semen Myristicae 20g, Rhizoma Et Radix Notopterygii 10g, Folium Isatidiss 30g and Concretio silicea Bambusae seu schizostachyi 10g.
Present invention also offers the preparation method of said medicine, specially:
Each crude drug is pulverized respectively, is mixed in proportion, mixture loads in percolator, and every 500g adds 50 degree~55 degree Chinese liquor 800g~1000g, under conditions of 30 DEG C~40 DEG C soak 20 hours~30 hours, adjust percolator valve, make white Yeast for brewing rice wine liquid slowly oozes, and oozing speed is 2~4mL per minute, to the color oozing transparent, collect the drip that oozes, Obtain percolate, concentrate, remove Chinese liquor, dry, pulverize, obtain dry drug powder.
Present invention also offers the preparation method of described feedstuff, specially:
The first step, prepares described drug powder according to above method;
Second step, the drug powder of each for remaining in described feedstuff component and first step preparation is sent in blender, Stir 30 minutes~1 hour at normal temperatures, obtain feedstuff.
Beneficial effects of the present invention:
The present invention provides a kind of medicine for preventing rabbit coccidiosis and feedstuff, can be alleviated because of coccidiosis using this medicine The effect such as the bleeding that leads to, dysentery, and enhancing body resistance, reaches effect for the treatment of both the principal and secondary aspects of a disease, and this medicine have no toxic side effect, Delay drug resistance, drug residue free, be that prevention coccidiosis select well.
Specific embodiment
The invention provides a kind of medicine for preventing rabbit coccidiosis, its crude drug includes the Radix Pulsatillae, Radix Sanguisorbae, gold silver Flower, Radix Glycyrrhizae, Lignum Sappan, Rhizoma Curcumae, Cortex Magnoliae Officinalis, Herba Centipedae, Herba Artemisiae Annuae, Resina Ferulae, Gaultheria, Herba Stellariae Alsiness, Conyza japonica, Caulis Sargentodoxae, the Radix Stemonae, Storage, Rhizoma Coptidis, Cortex Ailanthi, Bulbus Allii, Caulis Gneti, Fructus Choerospondiatis, Folium Ginseng, Semen Myristicae, Rhizoma Et Radix Notopterygii, Folium Isatidiss and Concretio silicea Bambusae seu schizostachyi.
Further, described medicine is only made up of above-mentioned raw materials medicine.
In described medicine the weight of each raw material be respectively Radix Pulsatillae 15g~25g, Radix Sanguisorbae 15g~25g, Flos Lonicerae 35g~ 45g, Radix Glycyrrhizae 15g~25g, Lignum Sappan 15g~25g, Rhizoma Curcumae 5g~15g, Cortex Magnoliae Officinalis 5g~15g, Herba Centipedae 5g~15g, Herba Artemisiae Annuae 15g ~25g, Resina Ferulae 5g~15g, Gaultheria 15g~25g, Herba Stellariae Alsiness 5g~15g, Conyza japonica 5g~15g, Caulis Sargentodoxae 5g~15g, hundred Portion 15g~25g, store 15g~25g, Rhizoma Coptidis 35g~45g, Cortex Ailanthi 15g~25g, Bulbus Allii 15g~25g, Caulis Gneti 15g~ 25g, Fructus Choerospondiatis 15g~25g, Folium Ginseng 15g~25g, Semen Myristicae 15g~25g, Rhizoma Et Radix Notopterygii 5g~15g, Folium Isatidiss 25g~35g and Concretio silicea Bambusae seu schizostachyi 5g~15g.
Further preferably, in described medicine, the weight of each raw material is respectively Radix Pulsatillae 18g~22g, Radix Sanguisorbae 18g~22g, gold Flos Lonicerae 38g~42g, Radix Glycyrrhizae 18g~22g, Lignum Sappan 18g~22g, Rhizoma Curcumae 8g~12g, Cortex Magnoliae Officinalis 8g~12g, Herba Centipedae 8g~ 12g, Herba Artemisiae Annuae 18g~22g, Resina Ferulae 8g~12g, Gaultheria 18g~22g, Herba Stellariae Alsiness 8g~12g, Conyza japonica 8g~12g, big blood Rattan 8g~12g, Radix Stemonae 18g~22g, store 18g~22g, Rhizoma Coptidis 38g~42g, Cortex Ailanthi 18g~22g, Bulbus Allii 18g~22g, buy MATENG 18g~22g, Fructus Choerospondiatis 18g~22g, Folium Ginseng 18g~22g, Semen Myristicae 18g~22g, Rhizoma Et Radix Notopterygii 8g~12g, Folium Isatidiss 28g~32g and Concretio silicea Bambusae seu schizostachyi 8g~12g.
Most preferably, in described medicine, the weight of each raw material is respectively Radix Pulsatillae 20g, Radix Sanguisorbae 20g, Flos Lonicerae 40g, Radix Glycyrrhizae 20g, Lignum Sappan 20g, Rhizoma Curcumae 10g, Cortex Magnoliae Officinalis 10g, Herba Centipedae 10g, Herba Artemisiae Annuae 20g, Resina Ferulae 10g, Gaultheria 20g, Herba Stellariae Alsiness 10g, Conyza japonica 10g, Caulis Sargentodoxae 10g, Radix Stemonae 20g, storage 20g, Rhizoma Coptidis 40g, Cortex Ailanthi 20g, Bulbus Allii 20g, Caulis Gneti 20g, Fructus Choerospondiatis 20g, Folium Ginseng 20g, Semen Myristicae 20g, Rhizoma Et Radix Notopterygii 10g, Folium Isatidiss 30g and Concretio silicea Bambusae seu schizostachyi 10g.
Present invention also offers the preparation method of said medicine, specially:
Each crude drug is pulverized respectively, is mixed in proportion, mixture loads in percolator, and every 500g adds 50 degree~55 degree Chinese liquor 800g~1000g, under conditions of 30 DEG C~40 DEG C soak 20 hours~30 hours, adjust percolator valve, make white Yeast for brewing rice wine liquid slowly oozes, and oozing speed is 2~4mL per minute, to the color oozing transparent, collect the drip that oozes, Obtain percolate, concentrate, remove Chinese liquor, dry, pulverize, obtain dry drug powder.
The present invention also provides a kind of feedstuff for preventing rabbit coccidiosis, and it includes above-mentioned drug powder, Semen Maydiss, rice Bran, bean cake, Testa Tritici, fish flour, bone meal and Sal.
Further, described feedstuff is only made up of above-mentioned raw materials.
In described feedstuff, the weight of each raw material is respectively drug powder 0.8kg~1.2kg, Semen Maydiss 45kg~55kg, rice chaff 27kg~33kg, bean cake 12kg~18kg, Testa Tritici 8kg~12kg, fish flour 2kg~4kg, bone meal 1kg~3kg, Sal 0.5kg~ 1.5kg.
In described feedstuff, the weight of each raw material is respectively drug powder 1kg, Semen Maydiss 50kg, rice chaff 20kg, bean cake 15kg, wheat Bran 10kg, fish flour 3kg, bone meal 2kg, Sal 1kg.
Present invention also offers the preparation method of described feedstuff, specially:
The first step, prepares described drug powder according to above method;
Second step, the drug powder of each for remaining in described feedstuff component and first step preparation is sent in blender, Stir 30 minutes~1 hour at normal temperatures, obtain feedstuff.
Each crude drug pharmacology is as follows:
The Radix Pulsatillae:Bitter in the mouth, cold in nature, enter stomach, large intestine channel, play the role of heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, being mainly used in the intestines and stomach has Damp and hot stagnant heating is suffered from abdominal pain, dysentery pus and blood, the treatment of the symptom such as tenesmus, to the hematodiarrhoea hematochezia effect of large intestine heat in blood relatively Good, the Radix Pulsatillae all has certain suppression to make dysentery bacterium, Bacillus typhi, bacillus subtilis, escherichia coli, Staphyloccocus aureus With.
Radix Sanguisorbae:Bitter in the mouth, acid, cold in nature, Return liver;Lung;Kidney;Large intestine channel, has a cooling blood for hemostasis, heat-clearing and toxic substances removing, healing up sore and subduing swelling Effect, cures mainly haematemesis, spitting of blood, epistaxis, and hematuria is had blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, leucorrhea with red and white discharge, sore, carbuncle and painful swelling, eczema, pudendal pruritus, Burn due to hot liquid or fire, snake bite and insect sting etc. is demonstrate,proved.
Flos Lonicerae:Latin name lonicerae japonicae flos, also known as Flos Lonicerae, Flos Lonicerae, Flos Lonicerae, two precious flowers, taste Sweet, cold in nature, enter the heart, lung, stomach, large intestine channel, there iss heat-clearing and toxic substances removing, and energy eliminating pathogenic heat from blood to cure dysentery, it is mainly used in affection due to external wind and heat, warm Febrile disease poison is relatively contained, or epidemic febrile disease from the beginning of pathogenic heat still when the part of the body cavity above the diaphragm housing the heart and lungs is not descending;Pyretic toxicity dysentery, stool hematochezia;Fever disease in summer is demonstrate,proved;Pyretic toxicity gathers Carbuncle sore from the beginning of, the heat person of swelling and ache, and other skin infections, this thing has preferable antipyretic effect, has antiinflammatory action, can promote Multiple pyococcuss and pathogenic entero becteria are had stronger bacteriostasis by the phagocytic function of leukocyte.
Radix Glycyrrhizae:Sweet in the mouth, mild-natured, enter 12 warps, have a heat-clearing and toxic substances removing, mediation property of medicine, the effect of expelling phlegm for arresting cough, and can spleen invigorating and In, relieving spasm to stop pain, it is mainly used in the abdominal distension and anorexia of weakness of the spleen and stomach, weak;Contracture pain in abdomen can be alleviated, relax some drugses Strong and toxicity, mitigating medicine stimulates to the toxic and side effects of body or to gastrointestinal, can play QI invigorating by adding Radix Glycyrrhizae Neutralization, the effect of each component of mediation.
Lignum Sappan:Latin name sappan lignum, sweet in the mouth, one-tenth, mild-natured, enter the heart, liver, large intestine channel, there is blood circulation promoting and blood stasis dispelling, disappear Effect of swollen pain relieving, for blood stasis amenorrhea, dysmenorrhea, puerperal stasis of blood, traumatic injury, fracture, carbuncle sore tumefacting virus etc. are demonstrate,proved, to multiple Tumor cell line has obvious inhibitory action.
Rhizoma Curcumae:Acrid in the mouth, hardship, warm in nature, enter liver, spleen channel, there is blood-breaking, effect of Xiao Ji Zhi Tong, for qi depression to blood stasis Caused abdominal mass lump in the abdomen, chest and abdomen stasis caused pain, amenorrhea, dysmenorrhea, abdominal distention, traumatic injury, blood stasis such as swells and ache at the card.
Cortex Magnoliae Officinalis:Bitter in the mouth, pungent, warm in nature, returns spleen warp;Stomach;Large intestine channel, has gas consumption product;Eliminating dampness except full;Lowering the adverse QI to relieve asthma Effect, cures mainly stagnation of QI due to dyspepsia;Abdominal distention constipation;Retention of dampness in middle-JIAO, gastral cavity ruffian is vomited and diarrhoea;
Phlegm stops up the circulation of vital energy in the wrong direction;Fullness sensation in chest is breathed with cough etc. is demonstrate,proved.
Herba Centipedae:Acrid in the mouth, warm in nature, enter lung, Liver Channel, there is cold-dispelling, clearing the nasal passage, eliminating phlegm and stopping cough, the work of dissipating blood stasis for subsidence of swelling With for exterior syndrome due to wind-cold, nasal obstruction watery nasal discharge and nasal sinusitis, cough with copious phlegm, pertussis, sore, carbuncle and painful swelling etc. is demonstrate,proved.
Herba Artemisiae Annuae:Latin name Artemisiae Annuae Herba, bitter in the mouth, pungent, cold in nature, Return liver, gallbladder meridian, there is clear void Heat, removing heat from blood removes and steams, and except steaming, effect of preventing the attack (or recurrence) of malaria, cures mainly pathogenic summer-heat and generates heat, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, Jaundice due to damp-heat etc. is demonstrate,proved.
Resina Ferulae:Bitter in the mouth, pungent, warm in nature, return kidney, stomach, there is removing food stagnancy, scattered painful abdominal mass, effect of parasite killing, for meat stagnation, the stasis of blood Mass formed by blood stasis abdominal mass, mass in abdomen, abdominal pain due to worm stagnation etc. is demonstrate,proved.
Gaultheria:Root for the white strain tree of Ericaceae Gaultheria plant or stem and leaf, acrid in the mouth, puckery, warm in nature, gas fragrance, tool There is expelling wind and removing dampness, cure mainly rheumatic arthritis, traumatic injury etc. is demonstrate,proved.
Herba Stellariae Alsiness:For the herb of Caryophyllaceae Herba stellariae mediae platymiscium Stellaria alsine Grim., acrid in the mouth, mild-natured, return lung, spleen channel, there is wind-dispelling and remove Wet, promoting blood circulation and detumescence, effect of removing toxic substances hemostasis, cure mainly flu, dysentery, rheumatic arthralgia, traumatic injury, venom, spit blood, wound Bleeding etc. is demonstrate,proved.
Conyza japonica:Bitter in the mouth, pungent, cold in nature, there is clearing away heat to alleviate pain, effect of dispelling pathogenic wind and eliminating phlegm, cure mainly laryngitis, pneumonia, swelling throat Bitterly, the card such as tonsillitiss.
Caulis Sargentodoxae:Bitter in the mouth, mild-natured, Return liver, large intestine channel, there is the eliminating carbuncle that relieves internal heat, promoting blood circulation to remove obstruction in the collateral, the effect of wind dispelling insecticide, master Control acute and chronic appendicitis, rheumatic arthralgia, bloody dysentery, stranguria with blood, menoxenia, infantile malnutrition, worm pain, injury from falling down etc. is demonstrate,proved.
The Radix Stemonae:Sweet in the mouth, hardship, slightly warm in nature, enter lung meridian, there is nourishing the lung to arrest cough, the effect of delousing parasite killing, the Radix Stemonae gentle and not Dry, property is kept and is not walked, and has the work(of using pungent drugs for dispersion and bitter drugs for purgation sending down the abnormal ascending QI again, be mainly used in newly all long cough, be especially suitable to consumptive fever chronic cough person, the modern times are used for preventing and treating The cough of chronic bronchitiss, the dry cough of pulmonary tuberculosis, pertussis etc. are demonstrate,proved.
Store:Latin name Polygoni Avicularis Herba, bitter in the mouth, cold nature, enter bladder warp, there is diuretic and lead to Drench, effect of killing parasites for relieving itching, for stranguria, especially sand Stranguria, stranguria caused by urinary stone, dysuria, jaundice due to damp-heat, dysentery, carry inferior card, Storage has significant diuresis.
Rhizoma Coptidis:Bitter in the mouth, cold in nature, enter the heart, lung, gallbladder, stomach, large intestine channel, there are heat clearing and damp drying, eliminating fire and detoxication, the work of cooling blood for improving eyesight With being usually used in treating the high fever coma of the fire of removing pathogen in the heart warp, the prosperous dysphoria and insomnia of heart-fire, and epidemic febrile disease, the symptom such as vexed, thirsty.
Cortex Ailanthi:Bitter in the mouth, puckery, cold in nature, enter large intestine, stomach, Liver Channel, there is heat clearing and damp drying, astringing intestine to stop diarrhea leukorrhagia stopping, hemostasis, the work of parasite killing With, for damp-heat dysentery, protracted dysentery and diarrhea, metrorrhagia, have blood in stool, hemorrhoid hematochezia, leukorrhagia, discharging fresh blood stool etc. is demonstrate,proved.
Bulbus Allii:Warm in nature, acrid in the mouth is put down;Enter spleen, stomach, lung meridian, there is warming middle-JIAO and help digestion, row stagnant gas, warming the spleen and stomach, removing food stagnancy, detoxify, kill Effect of worm, cure mainly eating accumulation, coldness and pain in the epigastrium, oedema turgor, have loose bowels, dysentery, malaria, pertussis, swollen ulcer drug, white bald tinea The disease such as skin ulcer, snake bite and insect sting and ancylostome, pinworm.
Caulis Gneti:Bitter in the mouth, slightly warm in nature, there is expelling wind and removing dampness, eliminating stasis to stop pain, effect of preventing phlegm from forming and stopping coughing, cure mainly rheumatic arthralgia, Lumbago, treating swelling and pain by traumatic injury, the injury of tendon and muscle of fracturing, ulcer haemorrhage, chronic tracheitiss, venom etc. is demonstrate,proved.
Fructus Choerospondiatis:Sweet in the mouth, acid, mild-natured, there is promoting flow of QI and blood, tranquilizing by nourishing the heart, effect of removing food stagnancy removing toxic substances, cure mainly stagnation of QI blood The stasis of blood, chest pain, shortness of breath and palpitation, neurasthenia, insomnia, bronchitis, dyspepsia abdominal distention, the card such as diarrhoea.
Folium Ginseng:Bitter in the mouth, sweet, cold in nature, attach to the lung and stomach meridians, there is QI invigorating, lung benefiting, driving away summer heat, the effect promoted the production of body fluid, cure mainly the deficiency of vital energy Cough, summer-heat is irritated, injury thirst, and the head is unclear, and tired weary grade of extremity is demonstrate,proved.
Semen Myristicae:Latin name Myristicae Semen, acrid in the mouth, hardship, warm in nature, enter spleen, stomach, large intestine channel, there is warming middle-JIAO puckery Intestinal, the effect of promoting the circulation of qi helps digestion, the card such as do not disappear for diarrhea of deficiency type, cold-dysentery, abdominal distention, lack of appetite vomiting, dyspepsia.
Rhizoma Et Radix Notopterygii:Latin name Notopterygii Rhizoma et Radix, acrid in the mouth, hardship, warm in nature, enter kidney, bladder warp, tool There are relieving exterior syndrome and dispelling cold, expelling wind and dampness, pain relieving, there is wind and cold and press from both sides wet exterior syndrome, symptoms include fever with aversion to cold, headache are such as wrapped up in, neck ridge Stiffback pain, limbs are heavy, joint is ached, and anemofrigid-damp arthralgia etc. is demonstrate,proved.
Folium Isatidiss:Latin name Isatidis Folium, bitter in the mouth, property Great Cold, GUIXIN, liver, gallbladder, stomach, have antipyretic and detoxicated, Cooling blood and dissolving purpura, effect of jaundice eliminating, can the excess-heat that divides of clearing heat in QI system, the pyretic toxicity of blood system can be solved again, be mainly used in caused by pestilence calentura it Hyperpyrexia sweating, excessive thirst taking fluids profusely;The flourishing speckle of fire-toxin is gone mad, the symptom such as haematemesis;The unconsciousness due to high fever of measles, rash color is purple dark;Liver and gall The damp and hot jaundice accumulateing steaming;The deafness and tinnitus of liver and gall fire liter;The card such as the pharyngalgia caused by fire stagnation pyretic toxicity, aphtha of the mouth and tongue, hepatitis.
Concretio silicea Bambusae seu schizostachyi:Lightly seasoned, mild-natured, there is preventing phlegm from forming and stopping coughing, promoting blood circulation to remove blood stasis, effect of expelling wind and removing dampness, cure mainly cough ant phlegm, one hundred days Cough, leukorrhagia, stomachache, rheumatic arthralgia, infantile convulsion, traumatic injury etc. is demonstrate,proved.
Hereinafter embodiments of the present invention are described in detail using embodiment, whereby to the present invention how application technology means To solve technical problem, and reach realizing process and fully understanding and implement according to this of technique effect.
Embodiment 1 drug powder 1
By Radix Pulsatillae 20g, Radix Sanguisorbae 20g, Flos Lonicerae 40g, Radix Glycyrrhizae 20g, Lignum Sappan 20g, Rhizoma Curcumae 10g, Cortex Magnoliae Officinalis 10g, sandwort Careless 10g, Herba Artemisiae Annuae 20g, Resina Ferulae 10g, Gaultheria 20g, Herba Stellariae Alsiness 10g, Conyza japonica 10g, Caulis Sargentodoxae 10g, Radix Stemonae 20g, storage 20g, Rhizoma Coptidis 40g, Cortex Ailanthi 20g, Bulbus Allii 20g, Caulis Gneti 20g, Fructus Choerospondiatis 20g, Folium Ginseng 20g, Semen Myristicae 20g, Rhizoma Et Radix Notopterygii 10g, Folium Isatidiss 30g and Concretio silicea Bambusae seu schizostachyi 10g pulverizes respectively, is mixed in proportion, and mixture loads in percolator, and every 500g adds 50 degree of Chinese liquor 1000g, soaks 30 hours under conditions of 30 DEG C, adjusts percolator valve, so that Chinese liquor medicinal liquid is slowly oozed, it is every for oozing speed Minute 3mL, to the color oozing transparent, collect the drip oozing, obtain percolate, concentrate, remove Chinese liquor, be dried, powder Broken, obtain dry drug powder 1.
Embodiment 2 drug powder 2
By Radix Pulsatillae 18g, Radix Sanguisorbae 18g, Flos Lonicerae 38g, Radix Glycyrrhizae 18g, Lignum Sappan 18g, Rhizoma Curcumae 8g, Cortex Magnoliae Officinalis 8g, Herba Centipedae 8g, Herba Artemisiae Annuae 18g, Resina Ferulae 8g, Gaultheria 18g, Herba Stellariae Alsiness 8g, Conyza japonica 8g, Caulis Sargentodoxae 8g, Radix Stemonae 18g, storage 18g, Rhizoma Coptidis 38g, Cortex Ailanthi 18g, Bulbus Allii 18g, Caulis Gneti 18g, Fructus Choerospondiatis 18g, Folium Ginseng 18g, Semen Myristicae 18g, Rhizoma Et Radix Notopterygii 8g, Folium Isatidiss 28g Pulverize respectively with Concretio silicea Bambusae seu schizostachyi 8g, be mixed in proportion, mixture loads in percolator, and every 500g adds 50 degree of Chinese liquor 1000g, 30 Soak 30 hours under conditions of DEG C, adjust percolator valve, so that Chinese liquor medicinal liquid is slowly oozed, oozing speed is 3mL per minute, extremely Till the color that oozes is transparent, collects the drip oozing, obtain percolate, concentrate, remove Chinese liquor, dry, pulverize, obtain drying Drug powder 2.
Embodiment 3 drug powder 3
By Radix Pulsatillae 22g, Radix Sanguisorbae 22g, Flos Lonicerae 42g, Radix Glycyrrhizae 22g, Lignum Sappan 22g, Rhizoma Curcumae 12g, Cortex Magnoliae Officinalis 12g, sandwort Careless 12g, Herba Artemisiae Annuae 22g, Resina Ferulae 12g, Gaultheria 22g, Herba Stellariae Alsiness 12g, Conyza japonica 12g, Caulis Sargentodoxae 12g, Radix Stemonae 22g, storage 22g, Rhizoma Coptidis 42g, Cortex Ailanthi 22g, Bulbus Allii 22g, Caulis Gneti 22g, Fructus Choerospondiatis 22g, Folium Ginseng 22g, Semen Myristicae 22g, Rhizoma Et Radix Notopterygii 12g, Folium Isatidiss 32g and Concretio silicea Bambusae seu schizostachyi 12g pulverizes respectively, is mixed in proportion, and mixture loads in percolator, and every 500g adds 50 degree of Chinese liquor 1000g, soaks 30 hours under conditions of 30 DEG C, adjusts percolator valve, so that Chinese liquor medicinal liquid is slowly oozed, it is every for oozing speed Minute 3mL, to the color oozing transparent, collect the drip oozing, obtain percolate, concentrate, remove Chinese liquor, be dried, powder Broken, obtain dry drug powder 3.
Embodiment 4 toxicity test
Embodiment 4 pharmacological toxicity is tested
Acute toxicity test data
Detectable
Serum AST, ALT detection kit are purchased from Qingdao Rui Sheng bio tech ltd
Testing equipment
Micro-200 semiautomatic biochemistry detector, analytical balance, dissecting instrument, syringe, test tube etc..
Test method
After raising through the adaptabilities of 3 days, it is divided at random 4 groups (male and female half and half), every group each 20;Matched group, 3 differences Medicine group (respectively 200g/kg body weight, 160g/kg body weight, 120g/kg body weight), matched group gavage normal saline, 3 medicines The drug powder 1 of the group gavage embodiment of the present invention 1 preparation, Chinese medicine feed additive is dissolved in water and gavages mice.
Testing index and method
(1) clinicing symptom observation:The mental status of daily viewing test Mus, diet situation, every day entry morbidity death feelings Condition.
(2) pathological observation:Cut open inspection is carried out for dead Mus and observes internal organs change.
(3) growth indexes are observed:Routine weighing is carried out to test Mus;Off-test, slaughter Mus weigh in, internal organs weight dirty Device assessment of indices:Cut open inspection rat, core dirty, spleen, liver, kidney, testis, ovary, weigh, calculate internal organs according to the following formula and refer to Number:Organ index=internal organs weight/body weight × 100.
(4) change in liver function is observed:After off-test, slaughter Mus, take blood separation serum, measure AST, ALT.
Data processing:Data above is analyzed counting using SPSS 11.0.
Clinicing symptom observation
Matched group and test group Mus, the mental status and diet desire, to external world respond have no obvious exception.Each group Mus Morbidity and death condition such as table 1 below.
Table 1
Packet Sum Dead (only) Mortality rate (%)
1(200g/kg) 20 0 0
2(160g/kg) 20 0 0
3(120g/kg) 20 0 0
Matched group 20 0 0
Pathological observation:Matched group and test group, Mus carry out after slaughtering cut open inspection observe have no observation internal organs obvious Pathological change.
Growth indexes are observed:Off-test, slaughters that Mus weigh in, internal organs weight analysis are shown in Table 2.
Table 2
Packet Liver index Cardiac index Renal index Lungs index Index and spleen index
1(200g/kg) 5.58±0.12 0.74±0.02 1.30±0.19 0.68±0.05 0.52±0.01
2(160g/kg) 5.49±0.19 0.73±0.05 1.21±0.13 0.67±0.03 0.50±0.03
3(120g/kg) 5.62±0.12 0.73±0.09 1.31±0.12 0.71±0.05 0.52±0.03
Matched group 5.86±0.21 0.71±0.02 1.33±0.11 0.70±0.07 0.50±0.02
Change in liver function is observed
After off-test, slaughter Mus, take blood separation serum, measure AST (glutamic oxaloacetic transaminase, GOT), ALT (third turn of ammonia of paddy Enzyme) it is shown in Table 3.Result display each group of data difference compared with healthy control group is not notable, all in normal range.
Table 3
Packet Sum ALT AST
1(200g/kg) 20 36.10±2.21 128.29±11.13
2(160g/kg) 20 36.17±2.12 130.16±12.32
3(120g/kg) 20 36.22±2.39 131.29±16.21
Matched group 20 37.31±4.12 130.62±13.27
Long term toxicity test data
Continuous to rat according to Chinese medicine feed additive 10g/kg, 20g/kg, 100g/kg of the present invention of embodiment 1 preparation Gastric infusion 3 months, the fur of animal, the colour of skin, ingest, activity, the routine blood test of animal all without exception, the Liver and kidney function such as urine, feces Deng blood parameters and animal main organs index all in normal range, and normal kinetic zero difference histopathologic examination Show, the important organ no pathological change such as the heart, liver, spleen, lung, kidney, adrenal gland, trachea, testis, ovary.Check after being discontinued two weeks The all no overt toxicity reactions of above indices, show no cumulative toxicity.
Embodiment 5 feedstuff 1
Drug powder 1 prepared by 1kg embodiment 1, Semen Maydiss 50kg, rice chaff 20kg, bean cake 15kg, Testa Tritici 10kg, fish flour 3kg, bone meal 2kg, Sal 1kg send in blender, stir 1 hour at normal temperatures, obtain feedstuff 1.
Comparative example 1 feedstuff 2
By Semen Maydiss 50kg, rice chaff 20kg, bean cake 15kg, Testa Tritici 10kg, fish flour 3kg, bone meal 2kg, Sal 1kg, 50g ground gram Pearl profit is sent in blender, stirs 1 hour at normal temperatures, obtains feedstuff 2.
Comparative example 2 feedstuff 3
Semen Maydiss 50kg, rice chaff 20kg, bean cake 15kg, Testa Tritici 10kg, fish flour 3kg, bone meal 2kg, Sal 1kg are sent into stirring In machine, stir 1 hour at normal temperatures, obtain feedstuff 3.
Embodiment 6 prophylactic tria
EXPERIMENTAL DESIGN and packet
Experimental rabbits are randomly divided into 4 groups, every group 30, every 2 raisings of cage, and number.First group is blank control group, The feedstuff 3 of feeding comparative example 2 preparation, second group to the 4th group is that infection mixes coccidian oocyst, second group of feeding embodiment 5 respectively The feedstuff 1 of preparation, the feedstuff 2 of the 3rd group of feeding comparative example 1 preparation, the feedstuff 3 of the 4th group of feeding comparative example 2 preparation, during test Between be 28 days.
Egg capsule is inoculated
After feeding pastille feedstuff 3d, every oral vaccination of infected group rabbit 1 × 105Individual mixing coccidian oocyst.
Test index
Clinical health and analyse observation
The mental status of daily observational record experimental rabbit, appetite, feces situation and feed consumption rate.Dead if any rabbit in test Die, then anatomic observation pathological change in time, slaughter rabbit after off-test and observe pathological changes.
Weigh
In test the 0th, 7,14,21 and 28 days respectively by only weighing.
Feed conversion rate
Computing formula is:Feed conversion rate=day feed consumption/Average weight increasing a day
Coccidian oocyst discharges statistics
Collect every rabbit feces in test within 0th, 7,14,21 and 28 days, with Mai Kemasiteshi method (McMaster ' s Method) calculate the worm's ovum number (e.p.g) in its every gram feces.When egg capsule density is too big, counted after stepwise dilution.
Effect of drugs judges
By clinical observation and analyse observation, with egg sac number, daily gain as index, medicine group and matched group are carried out t inspection Test, and judge effect of drugs.
4th group started 4 phenomenons having loose bowels on 7th, and 6 loss of appetite, and feed intake reduces, the 13rd Occur dead 3, take feces and gallbladder plate coating checking it is seen that many coccidian oocysts, to the 28th day, groupment occurs and adopts within 14th Food declines, and spirit is depressed, all has phenomenon of having loose bowels to occur, to off-test dead 16 altogether.Second group of whole process only has 1 rabbit Son is had loose bowels, and death, and microscopy does not find encephalitozoon cuniculi, 5 phenomenons having loose bowels of the 3rd group of appearance, does not occur dead Die, microscopy does not find encephalitozoon cuniculi, total result is shown in Table 1.
Table 1 condition of morbidity death
Group Test number Sickness rate Mortality rate
First group 30 0 0
Second group 30 0 0
3rd group 30 16.7% (5/30) 0
4th group 30 100% (30/30) 53.3% (16/30)
Anticoccidial effect, the results are shown in Table 2.
Table 2 coccidian oocyst discharges situation of change (egg sac number e.p.g × 105/ g feces)
Group 0 day 7 days 14 days 21 days 28 days
First group Do not detect Do not detect Do not detect Do not detect Do not detect
Second group Do not detect 1.39±0.11 Do not detect Do not detect Do not detect
3rd group Do not detect 3.92±0.17 1.76±0.13 0.05±0.01 Do not detect
4th group Do not detect 17.39±1.59 59.26±2.10 37.93±1.03 29.61±2.72
During test, carry out 5 feces Coccidians, the worm egg sac number result of table 2 shows, the medicine providing using the present invention Thing powder, worm egg sac number is similar to blank control group, do not occur what change, preventive effect clearly, using ground gram When detecting within the 7th day, worm egg sac number dramatically increases pearl profit group compared with blank control group, subsequently drastically declines, inhibition is very Good, do not write using the infected group worm's ovum capsule digital display of any medicine and rise.
Daily gain situation, the results are shown in Table 3.
Table 3 daily gain situation compares g
Group Averagely play starting weight Averagely end weight Averagely day increment
First group 993.19±46.17 1347.31±79.83 12.6±3.1
Second group 971.60±57.56 1898.71±63.51 33.1±4.3
3rd group 986.35±20.17 1763.31±52.39 27.7±6.3
4th group 996.19±39.53 1356.29±57.29 12.9±2.5
All above-mentioned this intellectual properties of primary enforcement, do not set this new product of enforcement limiting other forms And/or new method.Those skilled in the art will be using this important information, and the above is changed, to realize similar execution feelings Condition.But, all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above, be only presently preferred embodiments of the present invention, is not the restriction that the present invention is made with other forms, appoints What those skilled in the art possibly also with the disclosure above technology contents changed or be modified as equivalent variations etc. Effect embodiment.But every without departing from technical solution of the present invention content, according to the present invention technical spirit to above example institute Any simple modification, equivalent variations and the remodeling made, still falls within the protection domain of technical solution of the present invention.

Claims (5)

1. a kind of feedstuff for preventing rabbit coccidiosis it is characterised in that:By the drug powder for preventing rabbit coccidiosis, jade Rice, rice chaff, bean cake, Testa Tritici, fish flour, bone meal and Sal are constituted;
The weight of each raw material respectively drug powder 0.8kg~1.2kg, Semen Maydiss 45kg~55kg, rice chaff 20kg, bean cake 12kg~ 18kg, Testa Tritici 8kg~12kg, fish flour 2kg~4kg, bone meal 1kg~3kg, Sal 0.5kg~1.5kg;
The crude drug of described drug powder is by the Radix Pulsatillae, Radix Sanguisorbae, Flos Lonicerae, Radix Glycyrrhizae, Lignum Sappan, Rhizoma Curcumae, Cortex Magnoliae Officinalis, Herba Centipedae, green grass or young crops Artemisia, Resina Ferulae, Gaultheria, Herba Stellariae Alsiness, Conyza japonica, Caulis Sargentodoxae, the Radix Stemonae, storage, Rhizoma Coptidis, Cortex Ailanthi, Bulbus Allii, Caulis Gneti, Fructus Choerospondiatis, people Rhizoma panacis majoris, Semen Myristicae, Rhizoma Et Radix Notopterygii, Folium Isatidiss and Concretio silicea Bambusae seu schizostachyi are constituted;
In described drug powder the weight of each raw material be respectively Radix Pulsatillae 15g~25g, Radix Sanguisorbae 15g~25g, Flos Lonicerae 35g~ 45g, Radix Glycyrrhizae 15g~25g, Lignum Sappan 15g~25g, Rhizoma Curcumae 5g~15g, Cortex Magnoliae Officinalis 5g~15g, Herba Centipedae 5g~15g, Herba Artemisiae Annuae 15g ~25g, Resina Ferulae 5g~15g, Gaultheria 15g~25g, Herba Stellariae Alsiness 5g~15g, Conyza japonica 5g~15g, Caulis Sargentodoxae 5g~15g, hundred Portion 15g~25g, store 15g~25g, Rhizoma Coptidis 35g~45g, Cortex Ailanthi 15g~25g, Bulbus Allii 15g~25g, Caulis Gneti 15g~ 25g, Fructus Choerospondiatis 15g~25g, Folium Ginseng 15g~25g, Semen Myristicae 15g~25g, Rhizoma Et Radix Notopterygii 5g~15g, Folium Isatidiss 25g~35g and Concretio silicea Bambusae seu schizostachyi 5g~15g.
2. feedstuff as claimed in claim 1 it is characterised in that:The weight of each raw material is respectively drug powder 1kg, Semen Maydiss 50kg, rice chaff 20kg, bean cake 15kg, Testa Tritici 10kg, fish flour 3kg, bone meal 2kg, Sal 1kg.
3. feedstuff as claimed in claim 1 or 2 it is characterised in that:In described drug powder, the weight of each raw material is respectively in vain Head father-in-law 18g~22g, Radix Sanguisorbae 18g~22g, Flos Lonicerae 38g~42g, Radix Glycyrrhizae 18g~22g, Lignum Sappan 18g~22g, Rhizoma Curcumae 8g~ 12g, Cortex Magnoliae Officinalis 8g~12g, Herba Centipedae 8g~12g, Herba Artemisiae Annuae 18g~22g, Resina Ferulae 8g~12g, Gaultheria 18g~22g, canopy Careless 8g~12g, Conyza japonica 8g~12g, Caulis Sargentodoxae 8g~12g, Radix Stemonae 18g~22g, store 18g~22g, Rhizoma Coptidis 38g~42g, Cortex Ailanthi 18g~22g, Bulbus Allii 18g~22g, Caulis Gneti 18g~22g, Fructus Choerospondiatis 18g~22g, Folium Ginseng 18g~22g, Semen Myristicae 18g~22g, Rhizoma Et Radix Notopterygii 8g~12g, Folium Isatidiss 28g~32g and Concretio silicea Bambusae seu schizostachyi 8g~12g.
4. feedstuff as claimed in claim 1 or 2 it is characterised in that:In described drug powder, the weight of each raw material is respectively in vain Head father-in-law 20g, Radix Sanguisorbae 20g, Flos Lonicerae 40g, Radix Glycyrrhizae 20g, Lignum Sappan 20g, Rhizoma Curcumae 10g, Cortex Magnoliae Officinalis 10g, Herba Centipedae 10g, Herba Artemisiae Annuae 20g, Resina Ferulae 10g, Gaultheria 20g, Herba Stellariae Alsiness 10g, Conyza japonica 10g, Caulis Sargentodoxae 10g, Radix Stemonae 20g, store 20g, Rhizoma Coptidis 40g, Cortex Ailanthi 20g, Bulbus Allii 20g, Caulis Gneti 20g, Fructus Choerospondiatis 20g, Folium Ginseng 20g, Semen Myristicae 20g, Rhizoma Et Radix Notopterygii 10g, Folium Isatidiss 30g and bamboo Yellow 10g.
5. the preparation method of feedstuff described in claim 1 or 2 is it is characterised in that include:
The first step, each crude drug in described drug powder is pulverized respectively, is mixed in proportion, and mixture loads in percolator, Every 500g adds 50 degree~55 degree of Chinese liquor 800g~1000g, soaks 20 hours~30 hours under conditions of 30 DEG C~40 DEG C, Adjust percolator valve, so that Chinese liquor medicinal liquid is slowly oozed, oozing speed is 2~4mL per minute, transparent to the color oozing is Only, collect the drip oozing, obtain percolate, concentrate, remove Chinese liquor, dry, pulverize, obtain dry drug powder;
Second step, the drug powder of each for remaining in described feedstuff component and first step preparation is sent in blender, normal The lower stirring of temperature 30 minutes~1 hour, obtains feedstuff.
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CN103110036A (en) * 2013-03-21 2013-05-22 曾龙 Compound feed capable of enhancing rabbit immunity and prompting rabbit growth
CN103250914A (en) * 2013-06-08 2013-08-21 潘李亮 Special feed additive for grown-up rex rabbits at age of above 90 days
JP2013215180A (en) * 2012-04-06 2013-10-24 Uurii:Kk Functional food for herbivorous animal
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CN103598460A (en) * 2013-10-25 2014-02-26 青岛华仁技术孵化器有限公司 Forage for preventing infectious bronchitis of chicken
CN103829041A (en) * 2014-03-26 2014-06-04 王媛 Young rabbit feed capable of preventing coccidiosis

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JP2013215180A (en) * 2012-04-06 2013-10-24 Uurii:Kk Functional food for herbivorous animal
CN103110036A (en) * 2013-03-21 2013-05-22 曾龙 Compound feed capable of enhancing rabbit immunity and prompting rabbit growth
CN103250914A (en) * 2013-06-08 2013-08-21 潘李亮 Special feed additive for grown-up rex rabbits at age of above 90 days
CN103495091A (en) * 2013-10-22 2014-01-08 山东新希望六和集团有限公司 Traditional Chinese medicine immune stimulant for preventing Eimeria tenella infections
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