CN104547764A - Medicine for recovering liver functions and preparation method thereof - Google Patents

Medicine for recovering liver functions and preparation method thereof Download PDF

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Publication number
CN104547764A
CN104547764A CN201410793435.6A CN201410793435A CN104547764A CN 104547764 A CN104547764 A CN 104547764A CN 201410793435 A CN201410793435 A CN 201410793435A CN 104547764 A CN104547764 A CN 104547764A
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China
Prior art keywords
medicine
parts
recovering
liver function
weight
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Pending
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CN201410793435.6A
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Chinese (zh)
Inventor
何庆军
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Individual
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Individual
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Priority to CN201410793435.6A priority Critical patent/CN104547764A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998Hordeum (barley)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a medicine for recovering liver functions. The medicine is prepared from the following medicinal raw materials in parts by weight: 8-12 parts of schisandra chinensis, 5-12 parts of white poria, 3-12 parts of polygonum cuspidatum, 3-6 parts of roasted malt, 2-6 parts of salviae miltiorrhizae and 3-6 parts of herba hyperici japonici. The medicine is prepared by the following steps: weighing the raw materials according to the weight proportion, screening, washing, drying, grinding into powder, uniformly mixing, disinfecting and sterilizing, and filling capsules. The medicine has the characteristics of low cost, good curative effect and small side effect. Clinical application of the medicine on 320 cases proves that the apparent effective rate is 95.6 percent, and the medicine is convenient and quick to use.

Description

A kind of for medicine recovering liver function and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, being specifically related to a kind of medicine for recovering liver function, also relating to the preparation method of this medicine simultaneously.
Background technology
Hepatopathy refers to the pathological changes occurring in liver, comprises hepatitis A, hepatitis B, hepatitis C, liver cirrhosis, fatization, alcoholic liver etc.
For hepatopathy, doctor trained in Western medicine is normally treated according to the enforcement of liver Index for examination.Clinical modal Liver function grade mainly contains thymol turbidity (TTT), the third paddy transaminase (GPT), total bilirubin (BIL) etc., and whether liver function is normally the important auxiliary diagnosis foundation determining hepatopath's health status.To treat hepatitis B, doctor trained in Western medicine falls enzyme medicine by using, and it is main for reducing serum alanine aminotransferase; To liver cirrhosis, hepatic ascites disease, usually adopt intravenous drip albumin therapy.Chinese traditional treatment hepatopathy, hepatopathy is divided into liver gallbladder damp-heat type, caused by hepatic stagnation qi stagnation, liver-depression and spleen-insufficiency type, liver-kidney yin deficiency and congestion of the liver silt type 5 type, and Therapeutic Method is a lot, comprises that determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs is write out a prescription, Chinese patent medicine, immobilised compound and single medicinal material etc.
At present, the medication amount of the treatment hepatopathy circulated in market is more, than if any the medicine falling enzyme, as liver-protecting tablet, Bifendate Tablet, Herba Sedi etc.; The medicine of jaundice eliminating class, such as Yinzhihuang" granula, Herba Artemisiae Scopariae preparation; The medicine of antiviral class, as lamivudine, adefovir ester etc., also has the medicine of hepatoprotective class, as vitamins, creatinine etc.But these medicines, have not only people's will part more, or costly weak curative effect or the course for the treatment of long, or side effect is large or dependency is strong.
But after liver disease, liver function recovery aspect, these effect of drugs for hepatopathy are then poor, and cost is high, the course for the treatment of is long, and specific aim is not strong.
Summary of the invention
The object of the present invention is to provide that a kind of cost is low, the medicine for recovering liver function that good effect, side effect are little.
Another object of the present invention is to provide this for recovering the preparation method of the medicine of liver function.
A kind of medicine for recovering liver function of the present invention, by weight, comprises following crude drug: Fructus Schisandrae Chinensis 8-12 part, Poria 5-12 part, Rhizoma Polygoni Cuspidati 3-12 part, Fructus Hordei Germinatus (parched) 3-6 part, Radix Salviae Miltiorrhizae 2-6 part, Herba Hyperici Japonici 3-6 part.
Preferred weight part of above-mentioned each raw material is:
Fructus Schisandrae Chinensis 10 parts, Poria 8.5 parts, Rhizoma Polygoni Cuspidati 7.5 parts, Fructus Hordei Germinatus (parched) 4.5 parts, Radix Salviae Miltiorrhizae 4 parts, Herba Hyperici Japonici 4.5 parts.
The preparation method of a kind of medicine for recovering liver function of the present invention, comprises the following steps:
(1) screen crude drug, sample by weight, cleaning, dry, be ground into powder, cross 150-200 mesh sieve;
(2) after mix homogeneously through sterilization, incapsulate, every dress powder 2g and get final product.
Medicine of the present invention adds required adjuvant according to a conventional method, can be made into other corresponding dosage forms such as tablet, pill.
The present invention compared with prior art, there is obvious beneficial effect, as can be known from the above technical solutions: the present invention selects Fructus Schisandrae Chinensis, Poria, Rhizoma Polygoni Cuspidati, Fructus Hordei Germinatus (parched), Radix Salviae Miltiorrhizae and Herba Hyperici Japonici to be raw material, the liver function damage because various hepatopathy causes is treated by the synergism between each medicine, there is efficient recovery liver function, treating both the principal and secondary aspects of a disease.Ingredient has effect of heat-clearing and toxic substances removing, nourishing the liver and kidney, soothing the liver hepatoprotective, stable curative effect.Its cost is low, good effect, not repeatedly, zest is little, toxic and side effects is little, and medication is convenient and swift.Clinical 320 examples use, and obvious effective rate is 95.6%.
Detailed description of the invention
The beneficial effect of medicine of the present invention is set forth further below by way of test example.
test example:the clinical observation of medicine of the present invention
Clinical data:
All cases 320 example.Wherein, male 165 example, women 155 example, max age 76 years old, minimal ages 19 years old.
Diagnostic criteria:
" disease of tcm Standardization of diagnosis and curative effect "
Therapeutic Method:
Oral medicine of the present invention, every day 2-3 time, each 4 30th is 1 course for the treatment of, 1-3 the course for the treatment of.
Criterion of therapeutical effect:
Effective: main clinic symptoms disappears;
Effective: main clinic symptoms is alleviated to some extent;
Invalid: main clinic symptoms is not improved.
Therapeutic outcome:
The liver function injured patient that 320 examples cause because of hepatopathy, uses medicine of the present invention to be used for the recovery of liver function, effective 306 examples, effective 12 examples, invalid 2 examples, obvious effective rate 95.6%, total effective rate 99.4%.
embodiment 1
For recovering a medicine for liver function, comprise the following steps:
(1) screen crude drug, take Fructus Schisandrae Chinensis 12g, Poria 5g, Rhizoma Polygoni Cuspidati 12g, Fructus Hordei Germinatus (parched) 3g, Radix Salviae Miltiorrhizae 6g, Herba Hyperici Japonici 6g, cleaning, dry, be ground into powder, cross 150 mesh sieves;
(2) after mix homogeneously through sterilization, incapsulate, every dress powder 2g and get final product.
embodiment 2
For recovering a medicine for liver function, comprise the following steps:
(1) screen crude drug, take Fructus Schisandrae Chinensis 8g, Poria 12g, Rhizoma Polygoni Cuspidati 3g, Fructus Hordei Germinatus (parched) 6g, Radix Salviae Miltiorrhizae 2g, Herba Hyperici Japonici 3g, cleaning, dry, be ground into powder, cross 170 mesh sieves;
(2) after mix homogeneously through sterilization, incapsulate, every dress powder 2g and get final product.
embodiment 3
For recovering a medicine for liver function, comprise the following steps:
(1) screen crude drug, take Fructus Schisandrae Chinensis 10g, Poria 8.5g, Rhizoma Polygoni Cuspidati 7.5g, Fructus Hordei Germinatus (parched) 4.5g, Radix Salviae Miltiorrhizae 4g, Herba Hyperici Japonici 4.5g, cleaning, dry, be ground into powder, cross 200 mesh sieves;
(2) after mix homogeneously through sterilization, incapsulate, every dress powder 2g and get final product.
The above, it is only preferred embodiment of the present invention, not any pro forma restriction is done to the present invention, anyly do not depart from technical solution of the present invention content, the any simple modification done above embodiment according to technical spirit of the present invention, equivalent variations and modification, all still belong in the scope of technical solution of the present invention.

Claims (3)

1. for recovering a medicine for liver function, by weight, comprise following crude drug: Fructus Schisandrae Chinensis 8-12 part, Poria 5-12 part, Rhizoma Polygoni Cuspidati 3-12 part, Fructus Hordei Germinatus (parched) 3-6 part, Radix Salviae Miltiorrhizae 2-6 part, Herba Hyperici Japonici 3-6 part.
2. a kind of medicine for recovering liver function as claimed in claim 1, by weight, comprises following crude drug: Fructus Schisandrae Chinensis 10 parts, Poria 8.5 parts, Rhizoma Polygoni Cuspidati 7.5 parts, Fructus Hordei Germinatus (parched) 4.5 parts, Radix Salviae Miltiorrhizae 4 parts, Herba Hyperici Japonici 4.5 parts.
3. the preparation method of a kind of medicine for recovering liver function as claimed in claim 1 or 2, comprises the following steps:
(1) screen crude drug, sample by weight, cleaning, dry, be ground into powder, cross 150-200 mesh sieve;
(2) after mix homogeneously through sterilization, incapsulate, every dress powder 2g and get final product.
CN201410793435.6A 2014-12-20 2014-12-20 Medicine for recovering liver functions and preparation method thereof Pending CN104547764A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105434636A (en) * 2015-12-21 2016-03-30 天农大(天津)生物科技有限公司 Traditional Chinese medicine composition used for treating duckling hepatitis, and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146362A (en) * 1996-09-27 1997-04-02 张庆兰 Capsule for anti hepatitis B
CN1233487A (en) * 1998-04-24 1999-11-03 汪东平 Medicine for treating hepatitis B
CN102028786A (en) * 2010-11-18 2011-04-27 中山市中医院 Preparation for treating chronic hepatitis B

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146362A (en) * 1996-09-27 1997-04-02 张庆兰 Capsule for anti hepatitis B
CN1233487A (en) * 1998-04-24 1999-11-03 汪东平 Medicine for treating hepatitis B
CN102028786A (en) * 2010-11-18 2011-04-27 中山市中医院 Preparation for treating chronic hepatitis B

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘宝密等: "论麦芽对肝炎的治疗作用", 《黑龙江中医药》 *
武谦虎: "《常用治疗肝病中药》", 31 January 2014, 中国医药科技出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105434636A (en) * 2015-12-21 2016-03-30 天农大(天津)生物科技有限公司 Traditional Chinese medicine composition used for treating duckling hepatitis, and preparation method thereof

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Application publication date: 20150429