CN104666991A - Pharmaceutical composition capable of preventing pig diarrhea and preparation method of pharmaceutical composition - Google Patents
Pharmaceutical composition capable of preventing pig diarrhea and preparation method of pharmaceutical composition Download PDFInfo
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Abstract
The invention discloses a pharmaceutical composition capable of preventing pig diarrhea and a preparation method of the pharmaceutical composition, and belongs to the technical field of traditional Chinese medicines. The pharmaceutical composition is prepared from the following raw materials: astragalus membranaceus, wolfberry fruit, Chinese yam, the root of chinese pulsatilla, dandelion, plantain herb, coptis chinensis, cortex phellodendri, purslane, puerarin, radix sophorae flavescentis, radix bupleuri, eupatorium, rhizoma atractylodis lanceae, mangnolia officinalis, pericarpium citri reticulatae, poria cocos, berberis poiretii schneid, tea leaves or tealeaf residues, liquorice, rice bran, egg shell, eggplant root, walnut leaf, walnut green seedcase, flower of poplar, sour pomegranate, garlic straw, aginomoto, flavoring orange essence, citric acid and kelp powder. The pharmaceutical composition disclosed by the invention is prepared from natural traditional Chinese medicines and nontoxic substances as raw materials, is applied to pig breeding, and has the advantages of being low in cost, fast in acting, high in recovery rate and low in medicine residue.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition preventing and treating diarrhea of pigs and preparation method thereof, belong to technical field of Chinese medicines.
Background technology
Porcine epizootic diarrhea is a kind of contact infectious intestinal disease caused by Porcine epidemic diarrhea virus, and feature is vomiting, diarrhoea, dehydration.Clinical change is very similar to pig transmissible gastrointestinal with symptom.1971 starting in Britain, and I crossed and this disease occurred successively early 1980s.Incubation period is generally 5-8 days, and artificial challenge is 8-24 hour incubation period.Main clinical symptoms is watery diarrhea, or has vomiting between diarrhoea.Vomit multiple be born in food or suck the breast after.The size at the age in weight year of symptom and variant, the age is less, and symptom is heavier.In one week age there is 3-4 days after diarrhoea in newborn piglet, and present serious dehydration and dead, mortality rate can reach 50%, and the highest mortality rate reaches 100%; After the larger piglet of part occurs, although do not have death, late growing stage speed is obviously comparatively slow, causes many economic losses to raiser.Due to one of symptom that piglet diarrhea is the comprehensive syndrome of systemic disease or gastroenteropathy, enjoy a trip to the mixed infection of antibacterial and virus.Sick temperature of pig body is normal or slightly high, and spirit is depressed, is suitable for going down, and wean pig, sow are often about a week of down in spirits, anorexia and persistent diarrhea, and recover normal gradually.Retarded growth after minority pig recovers.Growing and fattening pigs are all suffered from diarrhoea after raising infection with circle, rehabilitation after a week, mortality rate 1-3%.Adult Pig symptom is comparatively light, and the only performance vomiting had, severe one watery diarrhea 3-4 days can spontaneous recovery.Have plenty of because feeding and management is not good at, have plenty of because antibacterial or viral infection cause.Diarrhea of pigs popular when winter and the early spring, symptom and porcine epizootic diarrhea and transmissible gastroenteritis of swine closely similar, for raiser, if pig has infected this disease, all can fall ill in whole pig farm in a short time, reaches 1-2 month and just slowly calm down, can cause very large economic loss.Cause the reason of diarrhea of pigs can be divided into avirulence factor and causative factors two kinds substantially, wherein, avirulence factor comprise nutrition and feeding environment stress, as moist, variations in temperature, ablactation stress, Seasonal Temperature Difference etc.
And the regulation of " emergency notice about checking the antiviral drugs such as amantadine " issued according to the Ministry of Agriculture 2006, except the vaccine product produced through approval, use, the viral blight prohibitting the use other drug to prevent and treat class pathogenic microorganisms such as high pathogenic avian influenza to cause.Namely club is domestic prohibits the use antiviral treatment Animal diseases substantially, and normally used cured by antibiotics rate is very low, and cost is high, poor prognosis, easily causes drug residue, cures the symptoms, not the disease.Therefore, urgently work out that a kind of cost is low, the medicine of the high and low drug residue of instant effect, cure rate.
Summary of the invention
The object of the present invention is to provide a kind of pharmaceutical composition preventing and treating diarrhea of pigs and preparation method thereof, overcome the problem that in the medicine of existing control diarrhea of pigs, cure rate is low, cost is high, drug residue is more.
The technical scheme that technical solution problem of the present invention is taked is:
Prevent and treat a pharmaceutical composition for diarrhea of pigs, it is characterized in that, be made up of the material of following weight:
Radix Astragali 20-25, Fructus Lycii 15-20, Rhizoma Dioscoreae 20-25, Radix Pulsatillae 15-20, Herba Taraxaci 15-20, Herba Plantaginis 15-20, Rhizoma Coptidis 15-20, Cortex Phellodendri 15-20, Herba Portulacae 15-20, Radix Puerariae 15-20, Radix Sophorae Flavescentis 15-20, Radix Bupleuri 15-20, Herba Eupatorii 15-20, Atractylodes lancea (Thunb.) DC. 15-20, Cortex Magnoliae Officinalis 15-20, Pericarpium Citri Reticulatae 15-20, Poria 15-20, Radix Berberidis 20-25, Folium Camelliae sinensis or tealeaf residue 20-25, Radix Glycyrrhizae 20-25, Testa oryzae 60-80, Ovum crusta Gallus domesticus 20-25, Fructus Solani melongenae root 30-40, leaf of Semen Juglandis 30-40, Exocarpium Juglandis Immaturus 60-80, flower of poplar 30-40, Fructus punicae granati 20-25, garlic stalk 30-40, monosodium glutamate 2-5, flavoring orange essence 2-5, citric acid 0.5-1.5, Kelp Powder 5-8.
Further, be made up of the material of following weight:
The Radix Astragali 20, Fructus Lycii 15, Rhizoma Dioscoreae 20, the Radix Pulsatillae 15, Herba Taraxaci 20, Herba Plantaginis 20, Rhizoma Coptidis 20, Cortex Phellodendri 20, Herba Portulacae 20, Radix Puerariae 15, Radix Sophorae Flavescentis 15, Radix Bupleuri 15, Herba Eupatorii 20, Atractylodes lancea (Thunb.) DC. 20, Cortex Magnoliae Officinalis 20, Pericarpium Citri Reticulatae 20, Poria 20, Radix Berberidis 25, Folium Camelliae sinensis or tealeaf residue 25, Radix Glycyrrhizae 20, Testa oryzae 60, Ovum crusta Gallus domesticus 20, Fructus Solani melongenae root 30, leaf of Semen Juglandis 40, Exocarpium Juglandis Immaturus 60, flower of poplar 40, Fructus punicae granati 25, garlic stalk 40, monosodium glutamate 3, flavoring orange essence 3, citric acid 0.5, Kelp Powder 5.
Further, be made up of the material of following weight:
The Radix Astragali 20, Fructus Lycii 15, Rhizoma Dioscoreae 20, the Radix Pulsatillae 15, Herba Taraxaci 15, Herba Plantaginis 15, Rhizoma Coptidis 15, Cortex Phellodendri 15, Herba Portulacae 15, Radix Puerariae 15, Radix Sophorae Flavescentis 15, Radix Bupleuri 15, Herba Eupatorii 15, Atractylodes lancea (Thunb.) DC. 15, Cortex Magnoliae Officinalis 15, Pericarpium Citri Reticulatae 15, Poria 15, Radix Berberidis 20, Folium Camelliae sinensis or tealeaf residue 20, Radix Glycyrrhizae 20, Testa oryzae 60-80, Ovum crusta Gallus domesticus 20, Fructus Solani melongenae root 30, leaf of Semen Juglandis 30, Exocarpium Juglandis Immaturus 60, flower of poplar 30, Fructus punicae granati 20, garlic stalk 30, monosodium glutamate 2, flavoring orange essence 2, citric acid 1, Kelp Powder 7.
Further, be made up of the material of following weight:
The Radix Astragali 25, Fructus Lycii 20, Rhizoma Dioscoreae 25, the Radix Pulsatillae 20, Herba Taraxaci 20, Herba Plantaginis 20, Rhizoma Coptidis 20, Cortex Phellodendri 20, Herba Portulacae 20, Radix Puerariae 20, Radix Sophorae Flavescentis 20, Radix Bupleuri 20, Herba Eupatorii 20, Atractylodes lancea (Thunb.) DC. 15-20, Cortex Magnoliae Officinalis 20, Pericarpium Citri Reticulatae 20, Poria 20, Radix Berberidis 25, Folium Camelliae sinensis or tealeaf residue 25, Radix Glycyrrhizae 25, Testa oryzae 80, Ovum crusta Gallus domesticus 25, Fructus Solani melongenae root 40, leaf of Semen Juglandis 40, Exocarpium Juglandis Immaturus 80, flower of poplar 40, Fructus punicae granati 25, garlic stalk 40, monosodium glutamate 5, flavoring orange essence 5, citric acid 1.5, Kelp Powder 8.
Further, be made up of the material of following weight:
The Radix Astragali 23, Fructus Lycii 18, Rhizoma Dioscoreae 23, the Radix Pulsatillae 18, Herba Taraxaci 18, Herba Plantaginis 18, Rhizoma Coptidis 18, Cortex Phellodendri 18, Herba Portulacae 18, Radix Puerariae 18, Radix Sophorae Flavescentis 18, Radix Bupleuri 18, Herba Eupatorii 18, Atractylodes lancea (Thunb.) DC. 18, Cortex Magnoliae Officinalis 18, Pericarpium Citri Reticulatae 18, Poria 18, Radix Berberidis 23, Folium Camelliae sinensis or tealeaf residue 23, Radix Glycyrrhizae 23, Testa oryzae 70, Ovum crusta Gallus domesticus 23, Fructus Solani melongenae root 35, leaf of Semen Juglandis 35, Exocarpium Juglandis Immaturus 70, flower of poplar 35, Fructus punicae granati 23, garlic stalk 35, monosodium glutamate 3, flavoring orange essence 3, citric acid 1, Kelp Powder 6.
Present invention also offers a kind of preparation method of preventing and treating the pharmaceutical composition of diarrhea of pigs, it is characterized in that, comprise the following steps:
1. raw material is taken according to above-mentioned weight portion;
2. by step 1. in the Radix Astragali, Fructus Lycii, Rhizoma Dioscoreae, the Radix Pulsatillae, Herba Taraxaci, Herba Plantaginis, Rhizoma Coptidis, Cortex Phellodendri, Herba Portulacae, Radix Puerariae, Radix Sophorae Flavescentis, Radix Bupleuri, Herba Eupatorii, Atractylodes lancea (Thunb.) DC., Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Poria, Radix Berberidis, Folium Camelliae sinensis or tealeaf residue, Radix Glycyrrhizae, the bran powder that take be broken to more than 20 orders, obtain material one;
3. by step 1. in the Ovum crusta Gallus domesticus that takes dry through baking box, then be crushed to more than 100 orders, be ground into powder finally by super micron mill, then with step 1. in the citric acid, monosodium glutamate, flavoring orange essence, the Kelp Powder that take mix homogeneously, obtain material two;
4. by step 1. in take Fructus Solani melongenae root, leaf of Semen Juglandis, Exocarpium Juglandis Immaturus, flower of poplar, Fructus punicae granati, garlic stalk dry, be then crushed to more than 20 orders, obtain material three;
5. material one, material two and material three mix homogeneously are packed and be get final product.
Using method: first the above-mentioned pharmaceutical composition prepared is added mix homogeneously in feedstuff, obtain and directly feed according to common feed mode.
The Radix Astragali: warm in nature, sweet in the mouth.Tonifying Qi and lifting yang, benefit defends consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic detumescent.Cure mainly weakness of the spleen and stomach, lack of appetite asthenia, deficiency of vital energy blood prostration, exterior deficiency spontaneous perspiration, night sweat.
Fructus Lycii: sweet is flat.Return liver, kidney channel.Function cures mainly: nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
Rhizoma Dioscoreae: sweet, flat.Return spleen, lung, kidney channel.Function cures mainly: spleen reinforcing nourishing the stomach, and promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.
The Radix Pulsatillae: nature and flavor are bitter, cold.Gui Jing: return stomach, large intestine channel.Function cures mainly: heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery.For toxic-heat and blood stasis, pudendal pruritus leukorrhagia, amebic dysentery.
Herba Taraxaci: nature and flavor are bitter, sweet, cold.Gui Jing: return liver, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Herba Plantaginis: nature and flavor are sweet, cold.Gui Jing: return liver, kidney, lung, small intestine meridian.Function cures mainly: clearing away heat and promoting diuresis, eliminates the phlegm, removing heat from blood, removing toxic substances.For edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.
Rhizoma Coptidis: bitter, cold.Gui Jing: GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.
Cortex Phellodendri: bitter, cold.Gui Jing: return kidney, urinary bladder channel.Function cures mainly: heat clearing and damp drying, and pathogenic fire purging removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Herba Portulacae: nature and flavor acid, cold.Function cures mainly: clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.For bacillary dysentery, acute gastroenteritis, acute appendicitis, mastitis, bleeding hemorrhoids, leucorrhea; Furuncle swelling toxin is controlled in external, eczema, herpes zoster.
Radix Puerariae: nature and flavor are sweet, pungent, cool.Gui Jing: return spleen, stomach warp.Function cures mainly: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Radix Sophorae Flavescentis: nature and flavor are bitter, cold.Gui Jing: GUIXIN, liver, stomach, large intestine, urinary bladder channel.Function cures mainly: heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
Radix Bupleuri: pungent, micro-hardship, to be slightly cold; Return liver, gallbladder meridian.Induce sweat and bring down a fever, soothing liver-QI for relieving depression, elevate a turnable ladder yang-energy.This product is dredged to reach and kind be thoroughly longer than and discongest stagnant heat in the liver and gall, again can depressed liver-energy dispersing and QI regulating, pain over the hypochondriac region key medicine caused by treatment stagnant heat in the liver and gall, stagnation of QI due to depression of the liver.Pharmacological research confirms: the effects such as Radix Bupleuri has stronger antipyretic, antiinflammatory, antibacterial, antiviral, protects the liver, function of gallbladder promoting, calmness, analgesia.
Herba Eupatorii: nature and flavor are pungent, flat.Gui Jing returns spleen, stomach, lung meridian.Function cures mainly: removing dampness by means of aromatics, and appetizing of being amusing, delivers expelling summer-heat.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass vomiting and nausea, sweet greasy in mouth, halitosis, sialism, heat-damp in summer table disease, feeling of fullness in the head is uncomfortable in chest.
Atractylodes lancea (Thunb.) DC.: nature and flavor are warm in nature, acrid in the mouth, hardship.Function cures mainly: drying damp and strengthening spleen, dispels the wind, cold expelling, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity are warded off, rheumatic arthralgia, anemofrigid cold, nyctalopia nyctalopia.
Cortex Magnoliae Officinalis: toil, temperature.Enter spleen, stomach, large intestine channel.Have removing dampness intestinal stasis relieving, circulation of qi promoting relievingd asthma, wind dispelling analgesic effect.
Pericarpium Citri Reticulatae: nature and flavor are bitter, pungent, temperature.Return lung, spleen channel.Function cures mainly: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Poria: sweet light is flat.Enter the heart, spleen, lung meridian.Eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Control dysuria, edema distension, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.
Radix Berberidis: nature and flavor are bitter; Cold in nature; Gui Jing: liver; Stomach; Large intestine channel; Function cures mainly: heat clearing away; Dampness; Eliminating fire and detoxication.Main dysentery due to damp-heat profit; Diarrhoea; Jaundice; Eczema; Skin infection; Aphtha; Conjunctival congestion; Pharyngalgia
Folium Camelliae sinensis: property bitter but sweet flavor is cool.Gui Jing enters the heart, lung, stomach warp.Function cures mainly: refresh oneself, and relieving thirst and restlessness is reduced phlegm, and helps digestion, diuresis, removing toxic substances.Control headache, blurred vision, kind sleeping of sleeping, restlessness and thirst, food stagnation expectorant is stagnant, malaria, dysentery more.
Radix Glycyrrhizae: sweet, flat.GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, grows and coughs lung moistening, and emergency is detoxified, and is in harmonious proportion hundred medicines.Cure mainly laryngopharynx swelling and pain, cellulitis skin infection, gastrointestinal ulceration and solution poison of drug, alimentary toxicosis etc.Radix Glycyrrhizae agent have antiinflammatory and resistance state reflection function, therefore in doctor trained in Western medicine clinically mainly as demulcent.
Testa oryzae is also known as Testa oryzae, and nature and flavor are sweet; Pungent; Temperature; Return through large intestine; Stomach warp.Function cures mainly: appetizing; The therapeutic method to keep the adverse QI flowing downwards.Main dysphagic; Regurgitation; Beriberi.
Ovum crusta Gallus domesticus: nature and flavor are lightly seasoned; Property is put down; Return through stomach; Kidney channel, function cures mainly: convergence; Antacid; Bone strengthening; Hemostasis; Improving eyesight.Main gastric abscess; Regurgitation; Acid regurgitation; Rickets of child; Various hemorrhage; The raw nebula film of order; Chancre pox poison.
Fructus Solani melongenae root: nature and flavor: sweet is cool.Function cures mainly: clearing away heat-damp and promoting diuresis, dispelling wind stopping cough, astringing to arrest bleeding.For rheumatic arthritis, senile chronic tracheitis, edema, chronic cough, chronic dysentery, leucorrhea, seminal emission, hematuria, has blood in stool; External treating chilblain.
Leaf of Semen Juglandis: nature and flavor are bitter, puckery, flat.Poisonous.Function cures mainly: removing toxic substances, detumescence.For Corium elephatis kind, leukorrhagia, scabies.
Exocarpium Juglandis Immaturus has another name called Exocarpium Juglandis Immaturus, and nature and flavor are bitter; Puckery; Property is put down; Return through liver; Spleen; Stomach warp, function cures mainly: pain relieving; Cough-relieving; Antidiarrheal; Removing toxic substances; Parasite killing.Main epigastric pain; Dysmenorrhea; Chronic cough; To have loose bowels chronic dysentery; Carbuncle sore tumefacting virus; Stubborn dermatitis; Tinea alba; Vitiligo.
Flower of poplar: nature and flavor are bitter; Cold in nature, return through large intestine channel, function cures mainly: heat-clearing and toxic substances removing; Removing dampness dysentery relieving.Main bacterium dysentery; Enteritis.
Fructus punicae granati: nature and flavor acid; Warm in nature, function cures mainly: quench the thirst; Astringing intestine to stop diarrhea; Hemostasis.Main Tianjin wound is yearningly dry; Slide and rush down; Chronic dysentery; Metrorrhagia; Leukorrhagia.
Garlic stalk is of high nutritive value, crude fiber content is low, have high value containing enriching garlicin, both can develop as feed resource, can improve feedstuff feeding effect again, and have bactericidal action as health care green additive.
Monosodium glutamate is the one of flavouring agent, and main component is sodium glutamate.The Main Function of monosodium glutamate is the delicate flavour increasing food, maximum in Chinese dishes, also can be used for soup and sauce.In this pharmaceutical composition, monosodium glutamate can cover the peculiar taste of Chinese medicine, avoids the problem that pig is unwilling to search for food.
Kelp Powder: the active component that kelp Rich grows containing abundant iodide and mineral, multivitamin and stimulating animal, adds Thallus Laminariae (Thallus Eckloniae) powder, can strengthen the appetite of pig, reach the object of fast well-fattened weightening finish, and can improve resistance against diseases in feedstuff.Mineral contained in Thallus Laminariae (Thallus Eckloniae) and various trace elements all exist with organic, are not easily oxidized, and pig to its absorbability will be good than other inorganic mineral many.And Kelp Powder can cover the peculiar taste of medicine, there is the effect of Synergistic with monosodium glutamate.
Flavoring orange essence has seasoning effect, and auxiliary monosodium glutamate and Kelp Powder, cover the peculiar taste of medicine on the one hand, promotes the desire of pig feed on the other hand.
Citric acid: add citric acid in pig starter feed, can wean ahead of time, improves efficiency of feed utilization 5% ~ 10%, increases sows farrowing amount.In growing-finishing pigs diets, add citric acid, can daily gain be improved, reduce feedstuff-meat ratio, improve protein digestibility, reduce back of the body fat thickness, improve meat and Carcass Characteristics.In addition, citric acid Fructus Citri Limoniae has very strong bactericidal action, can also appetite stimulator.
The invention has the beneficial effects as follows:
1. pharmaceutical composition of the present invention all adopts pure natural medical, nonhazardous, effectively can prevent, treat diarrhea of pigs, avoids antibiotic application in breeding process, and drug residue free.
2. all environmental pollution can not be caused in the raw material of pharmaceutical composition of the present invention and preparation process, and alleviate environmental pollution (leaf of Semen Juglandis in raw material, Exocarpium Juglandis Immaturus, garlic stalk etc. originally belong to agricultural wastes, and the present invention makes it be recycled utilization) to a certain extent.
3. pharmaceutical composition prevention diarrhea of pigs of the present invention, Be very effective, is applied to the treatment of diarrhea of pigs, and effectiveness comparison is obvious, and medicine of the present invention can not produce offending abnormal smells from the patient.Diarrhoeal diseases pig generally has the symptom of anorexia, and pharmaceutical composition of the present invention carries out composite to the component of medicine, eliminates offending abnormal smells from the patient, also has the effect increasing appetite.
Detailed description of the invention
In order to understand the present invention better, illustrate content of the present invention further below in conjunction with embodiment, but content of the present invention is not only confined to the following examples, embodiment should not regard as limiting the scope of the present invention.
Embodiment 1:
Formula: the Radix Astragali 20, Fructus Lycii 15, Rhizoma Dioscoreae 20, the Radix Pulsatillae 15, Herba Taraxaci 20, Herba Plantaginis 20, Rhizoma Coptidis 20, Cortex Phellodendri 20, Herba Portulacae 20, Radix Puerariae 15, Radix Sophorae Flavescentis 15, Radix Bupleuri 15, Herba Eupatorii 20, Atractylodes lancea (Thunb.) DC. 20, Cortex Magnoliae Officinalis 20, Pericarpium Citri Reticulatae 20, Poria 20, Radix Berberidis 25, Folium Camelliae sinensis or tealeaf residue 25, Radix Glycyrrhizae 20, Testa oryzae 60, Ovum crusta Gallus domesticus 20, Fructus Solani melongenae root 30, leaf of Semen Juglandis 40, Exocarpium Juglandis Immaturus 60, flower of poplar 40, Fructus punicae granati 25, garlic stalk 40, monosodium glutamate 3, flavoring orange essence 3, citric acid 0.5, Kelp Powder 5.
Preparation method:
1. raw material is taken according to above-mentioned weight portion;
2. by step 1. in the Radix Astragali, Fructus Lycii, Rhizoma Dioscoreae, the Radix Pulsatillae, Herba Taraxaci, Herba Plantaginis, Rhizoma Coptidis, Cortex Phellodendri, Herba Portulacae, Radix Puerariae, Radix Sophorae Flavescentis, Radix Bupleuri, Herba Eupatorii, Atractylodes lancea (Thunb.) DC., Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Poria, Radix Berberidis, Folium Camelliae sinensis or tealeaf residue, Radix Glycyrrhizae, the bran powder that take be broken to more than 20 orders, obtain material one;
3. by step 1. in the Ovum crusta Gallus domesticus that takes dry through baking box, then be crushed to more than 100 orders, be ground into powder finally by super micron mill, then with step 1. in the citric acid, monosodium glutamate, flavoring orange essence, the Kelp Powder that take mix homogeneously, obtain material two;
4. by step 1. in take Fructus Solani melongenae root, leaf of Semen Juglandis, Exocarpium Juglandis Immaturus, flower of poplar, Fructus punicae granati, garlic stalk dry, be then crushed to more than 20 orders, obtain material three;
5. material one, material two and material three mix homogeneously are packed and be get final product.
Embodiment 2:
Formula: the Radix Astragali 20, Fructus Lycii 15, Rhizoma Dioscoreae 20, the Radix Pulsatillae 15, Herba Taraxaci 15, Herba Plantaginis 15, Rhizoma Coptidis 15, Cortex Phellodendri 15, Herba Portulacae 15, Radix Puerariae 15, Radix Sophorae Flavescentis 15, Radix Bupleuri 15, Herba Eupatorii 15, Atractylodes lancea (Thunb.) DC. 15, Cortex Magnoliae Officinalis 15, Pericarpium Citri Reticulatae 15, Poria 15, Radix Berberidis 20, Folium Camelliae sinensis or tealeaf residue 20, Radix Glycyrrhizae 20, Testa oryzae 60-80, Ovum crusta Gallus domesticus 20, Fructus Solani melongenae root 30, leaf of Semen Juglandis 30, Exocarpium Juglandis Immaturus 60, flower of poplar 30, Fructus punicae granati 20, garlic stalk 30, monosodium glutamate 2, flavoring orange essence 2, citric acid 1, Kelp Powder 7.
Preparation method is with embodiment 1.
Embodiment 3:
Formula: the Radix Astragali 25, Fructus Lycii 20, Rhizoma Dioscoreae 25, the Radix Pulsatillae 20, Herba Taraxaci 20, Herba Plantaginis 20, Rhizoma Coptidis 20, Cortex Phellodendri 20, Herba Portulacae 20, Radix Puerariae 20, Radix Sophorae Flavescentis 20, Radix Bupleuri 20, Herba Eupatorii 20, Atractylodes lancea (Thunb.) DC. 15-20, Cortex Magnoliae Officinalis 20, Pericarpium Citri Reticulatae 20, Poria 20, Radix Berberidis 25, Folium Camelliae sinensis or tealeaf residue 25, Radix Glycyrrhizae 25, Testa oryzae 80, Ovum crusta Gallus domesticus 25, Fructus Solani melongenae root 40, leaf of Semen Juglandis 40, Exocarpium Juglandis Immaturus 80, flower of poplar 40, Fructus punicae granati 25, garlic stalk 40, monosodium glutamate 5, flavoring orange essence 5, citric acid 1.5, Kelp Powder 8.
Preparation method is with embodiment 1.
Embodiment 4:
Formula: the Radix Astragali 23, Fructus Lycii 18, Rhizoma Dioscoreae 23, the Radix Pulsatillae 18, Herba Taraxaci 18, Herba Plantaginis 18, Rhizoma Coptidis 18, Cortex Phellodendri 18, Herba Portulacae 18, Radix Puerariae 18, Radix Sophorae Flavescentis 18, Radix Bupleuri 18, Herba Eupatorii 18, Atractylodes lancea (Thunb.) DC. 18, Cortex Magnoliae Officinalis 18, Pericarpium Citri Reticulatae 18, Poria 18, Radix Berberidis 23, Folium Camelliae sinensis or tealeaf residue 23, Radix Glycyrrhizae 23, Testa oryzae 70, Ovum crusta Gallus domesticus 23, Fructus Solani melongenae root 35, leaf of Semen Juglandis 35, Exocarpium Juglandis Immaturus 70, flower of poplar 35, Fructus punicae granati 23, garlic stalk 35, monosodium glutamate 3, flavoring orange essence 3, citric acid 1, Kelp Powder 6.
Preparation method is with embodiment 1.
The formula chosen in above-described embodiment 4 is applied to pig farm, Tengzhou.
Choose application and insecticide-applying way:
1 group: normal growth 2-6 age in week piglet 50; Pharmaceutical composition obtained in Example, nursing sow of feeding, 1 day pharmaceutical composition of feeding every 3 days, when feeding, every every day feeds 0.5kg, is entrained in feedstuff; Continue 3 weeks.
2 groups: normal growth 1.5-3 month pig 50; Direct-fed, 1 day pharmaceutical composition of feeding every 3 days, when feeding, every every day feeds 0.2kg, is entrained in feedstuff, is entrained in feedstuff; Continue 3 weeks.
3 groups: normal growth 4-6 month pig 50; Direct-fed, 1 day pharmaceutical composition of feeding every 3 days, when feeding, every every day feeds 0.2kg, is entrained in feedstuff, is entrained in feedstuff; Continue 3 weeks.
4 groups: diarrhoeal diseases pig 2 weeks-6 months pigs 50; 2-6 week piglet, its nursing sow of feeding, when feeding, every every day feeds 0.5kg, is entrained in feedstuff; The pig Direct-fed of more than 6 weeks to be fed 0.5kg every every day, is entrained in feedstuff, feeding time 7 days.(choice criteria of diarrhoeal diseases pig is: occur vomiting, symptom of diarrhea, simultaneously, anorexia depressed with spirit, the symptom such as to become thin).
For 1-3 group, in 3 weeks, all there is not symptom of diarrhea.
For 4 groups, all cure for 50 after seven days.
The formula chosen in above-described embodiment 1-3 is applied to pig farm, Tengzhou.
Choose application and insecticide-applying way:
5 groups: choose diarrhoeal diseases pig 2 weeks-6 months pigs 50; Be divided into three groups, wherein, 2-6 week piglet, its nursing sow of feeding, when feeding, every every day feeds 0.5kg (pharmaceutical composition in embodiment 1), is entrained in feedstuff; The pig Direct-fed of more than 6 weeks to be fed 0.5kg every every day, is entrained in feedstuff, feeding time 7 days.(choice criteria of diarrhoeal diseases pig is: occur vomiting, symptom of diarrhea, simultaneously, anorexia depressed with spirit, the symptom such as to become thin).
6 groups: choose diarrhoeal diseases pig 2 weeks-6 months pigs 50; Be divided into three groups, wherein, 2-6 week piglet, its nursing sow of feeding, when feeding, every every day feeds 0.5kg (pharmaceutical composition in embodiment 2), is entrained in feedstuff; The pig Direct-fed of more than 6 weeks to be fed 0.5kg every every day, is entrained in feedstuff, feeding time 7 days.(choice criteria of diarrhoeal diseases pig is: occur vomiting, symptom of diarrhea, simultaneously, anorexia depressed with spirit, the symptom such as to become thin).
7 groups: choose diarrhoeal diseases pig 2 weeks-6 months pigs 50; Be divided into three groups, wherein, 2-6 week piglet, its nursing sow of feeding, when feeding, every every day feeds 0.5kg (pharmaceutical composition in embodiment 1), is entrained in feedstuff; The pig Direct-fed of more than 6 weeks to be fed 0.5kg every every day, is entrained in feedstuff, feeding time 7 days.(choice criteria of diarrhoeal diseases pig is: occur vomiting, symptom of diarrhea, simultaneously, anorexia depressed with spirit, the symptom such as to become thin).
For 5 groups, 49 healings after seven days, 1 symptom is obviously alleviated.
For 6 groups, 49 healings after seven days, 1 symptom is obviously alleviated.
For 7 groups, all cure for 50 after seven days.
Claims (6)
1. prevent and treat a pharmaceutical composition for diarrhea of pigs, it is characterized in that, be made up of the material of following weight:
Radix Astragali 20-25, Fructus Lycii 15-20, Rhizoma Dioscoreae 20-25, Radix Pulsatillae 15-20, Herba Taraxaci 15-20, Herba Plantaginis 15-20, Rhizoma Coptidis 15-20, Cortex Phellodendri 15-20, Herba Portulacae 15-20, Radix Puerariae 15-20, Radix Sophorae Flavescentis 15-20, Radix Bupleuri 15-20, Herba Eupatorii 15-20, Atractylodes lancea (Thunb.) DC. 15-20, Cortex Magnoliae Officinalis 15-20, Pericarpium Citri Reticulatae 15-20, Poria 15-20, Radix Berberidis 20-25, Folium Camelliae sinensis or tealeaf residue 20-25, Radix Glycyrrhizae 20-25, Testa oryzae 60-80, Ovum crusta Gallus domesticus 20-25, Fructus Solani melongenae root 30-40, leaf of Semen Juglandis 30-40, Exocarpium Juglandis Immaturus 60-80, flower of poplar 30-40, Fructus punicae granati 20-25, garlic stalk 30-40, monosodium glutamate 2-5, flavoring orange essence 2-5, citric acid 0.5-1.5, Kelp Powder 5-8.
2. the pharmaceutical composition of control diarrhea of pigs according to claim 1, is characterized in that, is made up of the material of following weight:
The Radix Astragali 20, Fructus Lycii 15, Rhizoma Dioscoreae 20, the Radix Pulsatillae 15, Herba Taraxaci 20, Herba Plantaginis 20, Rhizoma Coptidis 20, Cortex Phellodendri 20, Herba Portulacae 20, Radix Puerariae 15, Radix Sophorae Flavescentis 15, Radix Bupleuri 15, Herba Eupatorii 20, Atractylodes lancea (Thunb.) DC. 20, Cortex Magnoliae Officinalis 20, Pericarpium Citri Reticulatae 20, Poria 20, Radix Berberidis 25, Folium Camelliae sinensis or tealeaf residue 25, Radix Glycyrrhizae 20, Testa oryzae 60, Ovum crusta Gallus domesticus 20, Fructus Solani melongenae root 30, leaf of Semen Juglandis 40, Exocarpium Juglandis Immaturus 60, flower of poplar 40, Fructus punicae granati 25, garlic stalk 40, monosodium glutamate 3, flavoring orange essence 3, citric acid 0.5, Kelp Powder 5.
3. the pharmaceutical composition of control diarrhea of pigs according to claim 1, is characterized in that, is made up of the material of following weight:
The Radix Astragali 20, Fructus Lycii 15, Rhizoma Dioscoreae 20, the Radix Pulsatillae 15, Herba Taraxaci 15, Herba Plantaginis 15, Rhizoma Coptidis 15, Cortex Phellodendri 15, Herba Portulacae 15, Radix Puerariae 15, Radix Sophorae Flavescentis 15, Radix Bupleuri 15, Herba Eupatorii 15, Atractylodes lancea (Thunb.) DC. 15, Cortex Magnoliae Officinalis 15, Pericarpium Citri Reticulatae 15, Poria 15, Radix Berberidis 20, Folium Camelliae sinensis or tealeaf residue 20, Radix Glycyrrhizae 20, Testa oryzae 60-80, Ovum crusta Gallus domesticus 20, Fructus Solani melongenae root 30, leaf of Semen Juglandis 30, Exocarpium Juglandis Immaturus 60, flower of poplar 30, Fructus punicae granati 20, garlic stalk 30, monosodium glutamate 2, flavoring orange essence 2, citric acid 1, Kelp Powder 7.
4. the pharmaceutical composition of control diarrhea of pigs according to claim 1, is characterized in that, is made up of the material of following weight:
The Radix Astragali 25, Fructus Lycii 20, Rhizoma Dioscoreae 25, the Radix Pulsatillae 20, Herba Taraxaci 20, Herba Plantaginis 20, Rhizoma Coptidis 20, Cortex Phellodendri 20, Herba Portulacae 20, Radix Puerariae 20, Radix Sophorae Flavescentis 20, Radix Bupleuri 20, Herba Eupatorii 20, Atractylodes lancea (Thunb.) DC. 15-20, Cortex Magnoliae Officinalis 20, Pericarpium Citri Reticulatae 20, Poria 20, Radix Berberidis 25, Folium Camelliae sinensis or tealeaf residue 25, Radix Glycyrrhizae 25, Testa oryzae 80, Ovum crusta Gallus domesticus 25, Fructus Solani melongenae root 40, leaf of Semen Juglandis 40, Exocarpium Juglandis Immaturus 80, flower of poplar 40, Fructus punicae granati 25, garlic stalk 40, monosodium glutamate 5, flavoring orange essence 5, citric acid 1.5, Kelp Powder 8.
5. the pharmaceutical composition of control diarrhea of pigs according to claim 1, is characterized in that, is made up of the material of following weight:
The Radix Astragali 23, Fructus Lycii 18, Rhizoma Dioscoreae 23, the Radix Pulsatillae 18, Herba Taraxaci 18, Herba Plantaginis 18, Rhizoma Coptidis 18, Cortex Phellodendri 18, Herba Portulacae 18, Radix Puerariae 18, Radix Sophorae Flavescentis 18, Radix Bupleuri 18, Herba Eupatorii 18, Atractylodes lancea (Thunb.) DC. 18, Cortex Magnoliae Officinalis 18, Pericarpium Citri Reticulatae 18, Poria 18, Radix Berberidis 23, Folium Camelliae sinensis or tealeaf residue 23, Radix Glycyrrhizae 23, Testa oryzae 70, Ovum crusta Gallus domesticus 23, Fructus Solani melongenae root 35, leaf of Semen Juglandis 35, Exocarpium Juglandis Immaturus 70, flower of poplar 35, Fructus punicae granati 23, garlic stalk 35, monosodium glutamate 3, flavoring orange essence 3, citric acid 1, Kelp Powder 6.
6. a preparation method for the pharmaceutical composition of the control diarrhea of pigs according to claim 1-5, is characterized in that, comprise the following steps:
1. raw material is taken according to the arbitrary described weight portion of claim 1-5;
2. by step 1. in the Radix Astragali, Fructus Lycii, Rhizoma Dioscoreae, the Radix Pulsatillae, Herba Taraxaci, Herba Plantaginis, Rhizoma Coptidis, Cortex Phellodendri, Herba Portulacae, Radix Puerariae, Radix Sophorae Flavescentis, Radix Bupleuri, Herba Eupatorii, Atractylodes lancea (Thunb.) DC., Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Poria, Radix Berberidis, Folium Camelliae sinensis or tealeaf residue, Radix Glycyrrhizae, the bran powder that take be broken to more than 20 orders, obtain material one;
3. by step 1. in the Ovum crusta Gallus domesticus that takes dry through baking box, then be crushed to more than 100 orders, be ground into powder finally by super micron mill, then with step 1. in the citric acid, monosodium glutamate, flavoring orange essence, the Kelp Powder that take mix homogeneously, obtain material two;
4. by step 1. in take Fructus Solani melongenae root, leaf of Semen Juglandis, Exocarpium Juglandis Immaturus, flower of poplar, Fructus punicae granati, garlic stalk dry, be then crushed to more than 20 orders, obtain material three;
5. material one, material two and material three mix homogeneously are packed and be get final product.
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Application publication date: 20150603 |