CN105407885B - 包含ω-3脂肪酸和番茄的番茄红素的组合 - Google Patents

包含ω-3脂肪酸和番茄的番茄红素的组合 Download PDF

Info

Publication number
CN105407885B
CN105407885B CN201480024636.8A CN201480024636A CN105407885B CN 105407885 B CN105407885 B CN 105407885B CN 201480024636 A CN201480024636 A CN 201480024636A CN 105407885 B CN105407885 B CN 105407885B
Authority
CN
China
Prior art keywords
composition
another embodiment
omega
acid
lycopene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201480024636.8A
Other languages
English (en)
Chinese (zh)
Other versions
CN105407885A (zh
Inventor
R·利维
N·哈达
T·珊德洛夫
M·塞尔卡
M·萨波琼尼克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lycored Ltd
Original Assignee
Lycored Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lycored Ltd filed Critical Lycored Ltd
Publication of CN105407885A publication Critical patent/CN105407885A/zh
Application granted granted Critical
Publication of CN105407885B publication Critical patent/CN105407885B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A61K31/035—Halogenated hydrocarbons having aliphatic unsaturation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201480024636.8A 2013-04-04 2014-04-03 包含ω-3脂肪酸和番茄的番茄红素的组合 Expired - Fee Related CN105407885B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361808246P 2013-04-04 2013-04-04
US61/808,246 2013-04-04
PCT/IL2014/050329 WO2014162313A1 (en) 2013-04-04 2014-04-03 Anti-inflammatory synergistic combinations comprising omega-3 fatty acid and tomato lycopene

Publications (2)

Publication Number Publication Date
CN105407885A CN105407885A (zh) 2016-03-16
CN105407885B true CN105407885B (zh) 2019-04-30

Family

ID=51657661

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480024636.8A Expired - Fee Related CN105407885B (zh) 2013-04-04 2014-04-03 包含ω-3脂肪酸和番茄的番茄红素的组合

Country Status (7)

Country Link
US (2) US9901562B2 (enExample)
EP (1) EP2981256B1 (enExample)
JP (2) JP2016519101A (enExample)
CN (1) CN105407885B (enExample)
AU (1) AU2014246728B2 (enExample)
ES (1) ES2932248T3 (enExample)
WO (1) WO2014162313A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9901562B2 (en) * 2013-04-04 2018-02-27 Lycored Ltd. Anti-inflammatory omega-3 synergistic combinations
CN108354919A (zh) * 2017-12-29 2018-08-03 广东海洋大学 一种用于提高抗氧化功能的不饱和脂肪酸组合物及其应用
CN111053248A (zh) * 2018-10-16 2020-04-24 东莞市维康医疗投资有限公司 一种地龙蛋白口服液及其制备方法
CA3153891A1 (en) 2019-10-09 2021-04-15 Gregory CUMBERFORD Compositions with purified bombyx mori cocoon silk peptide fiber and refined buglossoides arvensis seed oil, and related methods
US11707497B2 (en) 2019-10-09 2023-07-25 Brain Health Holding Llc Methods and compositions with purified Bombyx mori cocoon silk peptide fiber and refined Buglossoides arvensis seed oil providing anti-inflammatory effects and neuroprotection for disease states
EP4041207B1 (en) * 2019-10-10 2026-02-25 Lycored Ltd. Compositions and methods for inhibiting collagen loss
US12582692B2 (en) 2024-01-03 2026-03-24 Hazel's Holistic, Llc Methods and kits for reducing microplastics levels and/or reducing or minimizing microplastics accumulation rates in subjects

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011057183A1 (en) * 2009-11-06 2011-05-12 Alcon Research, Ltd. Nutritional supplements for relief of dry eye
CN102355894A (zh) * 2009-01-19 2012-02-15 利科雷德有限公司 类胡萝卜素和多酚的协同组合

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837311A (en) 1993-12-13 1998-11-17 Makhteshim Chemical Works Ltd. Industrial processing of tomatoes and product thereof
ATE264063T1 (de) 1998-02-13 2004-04-15 Nestle Sa Garnierte toast
WO2001051088A1 (en) * 2000-01-07 2001-07-19 Anthony Cincotta Composition for reducing plasma triglycerides, platelet aggregation, and oxidative capacity
AU2003205737A1 (en) 2002-02-15 2003-09-04 Humboldt Universitaet Compositions comprising lycopene for the treatment and prevention of angiogenesis associated pathologies
JP2009537467A (ja) 2006-05-15 2009-10-29 ディーエスエム アイピー アセッツ ビー．ブイ． 前立腺癌に対する新規活性物
KR20090109793A (ko) * 2008-04-16 2009-10-21 홉킨스바이오연구센터(주) 크랜베리 추출물 또는 복분자 추출물을 함유하는건강기능성식품 조성물
US20110008901A1 (en) 2009-07-07 2011-01-13 Kiernan Urban A Apolipoprotein ciii in pre- and type 2 diabetes
EP2976070B1 (en) * 2013-03-19 2021-05-12 Lycored Ltd. Anti-inflammatory synergistic combinations of astaxanthin with lycopene and carnosic acid
US9901562B2 (en) * 2013-04-04 2018-02-27 Lycored Ltd. Anti-inflammatory omega-3 synergistic combinations

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102355894A (zh) * 2009-01-19 2012-02-15 利科雷德有限公司 类胡萝卜素和多酚的协同组合
WO2011057183A1 (en) * 2009-11-06 2011-05-12 Alcon Research, Ltd. Nutritional supplements for relief of dry eye

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
A Dietary Mixture Containing Fish Oil,Resveratrol, Lycopene, Catechins, and Vitamins E and C Reduces Atherosclerosis in Transgenic Mice;Lars Verschuren等;《The Journal of Nutrition》;20110316 *
Combination of Antioxidant Supplements Improved Cognitive Function in the Elderly;Fumihiko Yasuno等;《Journal of Alzheimer’s Disease》;20121231(第32期);第895–903页 *
Concomitant consumption of lycopene and fish oil inhibits tumor growth and progression in a mouse xenograft model of colon cancer;Feng-Yao Tang等;《Mol. Nutr. Food Res》;20121231(第56期);第1520-1531页 *
Effect of consumption of tomato juice enriched with n-3 polyunsaturated fatty acids on the lipid profile, antioxidant biomarker status, and cardiovascular disease risk in healthy women;F. J. Garcı´a-Alonso等;《Eur J Nutr》;20121031(第51期);第415-424页 *

Also Published As

Publication number Publication date
EP2981256B1 (en) 2022-08-24
AU2014246728A1 (en) 2015-10-29
EP2981256A4 (en) 2016-11-23
US20160303063A1 (en) 2016-10-20
US20180153843A1 (en) 2018-06-07
JP2016519101A (ja) 2016-06-30
WO2014162313A1 (en) 2014-10-09
EP2981256A1 (en) 2016-02-10
US9901562B2 (en) 2018-02-27
US10154980B2 (en) 2018-12-18
JP6803898B2 (ja) 2020-12-23
ES2932248T3 (es) 2023-01-17
CN105407885A (zh) 2016-03-16
AU2014246728B2 (en) 2019-01-31
JP2019052168A (ja) 2019-04-04

Similar Documents

Publication Publication Date Title
CN105324114B (zh) 虾青素抗炎增效组合
JP6803898B2 (ja) オメガ−３脂肪酸およびトマトリコペンを含む抗炎症性相乗的組み合わせ
CN106580919B (zh) 一种灵芝孢子油微囊粉及其制备方法和应用
JP2013532666A (ja) 抗疲労組成物、その製剤及び応用
CN101601695B (zh) 灵芝三萜提取物的自微乳化纳米组合物及其制备方法
CN110200833A (zh) 一种根皮素纳米乳制剂及其制备方法和应用
CN105963254B (zh) 一种辅酶q10药物组合物及其制备工艺
Sunagawa et al. A novel drug delivery system of oral curcumin markedly improves efficacy of treatment for heart failure after myocardial infarction in rats
CN102511821B (zh) 番茄红素葡萄籽提取物复合降脂软胶囊制剂及其生产方法
CN101492489A (zh) 银莲花素a的提取方法及其脂微球制剂的制备方法
CN1698620B (zh) 一种可过滤除菌的葫芦素乳剂及制备方法
CN103690482A (zh) 以磷脂复合物为中间体的甘草酸自乳化制剂用浓缩液及制备方法
CN1957927B (zh) 三萜皂苷及其衍生物的脂微球制剂及其制备方法
CN103860578A (zh) 香菇多糖作为抗抑郁症药物的用途
TW200946140A (en) Stable-type Cucurbitacin medicinal liquid compositions
CN103599089B (zh) 非诺贝特油溶缓释药物制剂组合物
JP5760098B2 (ja) 前立腺がん治療薬
CN107308159A (zh) 一种提高伊拉地平生物利用度药物组合物
CN107308158A (zh) 一种提高非洛地平生物利用度的药物组合物

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20190430

CF01 Termination of patent right due to non-payment of annual fee