CN105377306B - Glp-1衍生物和其用途 - Google Patents

Glp-1衍生物和其用途 Download PDF

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CN105377306B
CN105377306B CN201480035036.1A CN201480035036A CN105377306B CN 105377306 B CN105377306 B CN 105377306B CN 201480035036 A CN201480035036 A CN 201480035036A CN 105377306 B CN105377306 B CN 105377306B
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derivative
xaa
glp
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chem
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CN105377306A (zh
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S.里德茨-朗格
P.索尔伯格
J．科福伊德
I.佩特斯森
C.W.托诺伊
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Novo Nordisk AS
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CN201480035036.1A 2013-06-20 2014-06-19 Glp-1衍生物和其用途 Active CN105377306B (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP13173068.1 2013-06-20
EP13173068 2013-06-20
US201361841995P 2013-07-02 2013-07-02
US61/841995 2013-07-02
EP13175092.9 2013-07-04
EP13175092 2013-07-04
US201361845647P 2013-07-12 2013-07-12
US61/845647 2013-07-12
PCT/EP2014/062952 WO2014202727A1 (en) 2013-06-20 2014-06-19 Glp-1 derivatives and uses thereof

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Publication Number Publication Date
CN105377306A CN105377306A (zh) 2016-03-02
CN105377306B true CN105377306B (zh) 2020-03-17

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US (1) US10195255B2 (enExample)
EP (1) EP3010546B1 (enExample)
JP (1) JP6475233B2 (enExample)
KR (1) KR20160021183A (enExample)
CN (1) CN105377306B (enExample)
AU (1) AU2014283221A1 (enExample)
BR (1) BR112015030948A2 (enExample)
CA (1) CA2915922A1 (enExample)
ES (1) ES2646538T3 (enExample)
MX (1) MX2015016564A (enExample)
WO (1) WO2014202727A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
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EP3010546B1 (en) 2013-06-20 2017-08-09 Novo Nordisk A/S Glp-1 derivatives and uses thereof
JP6730278B2 (ja) * 2014-11-27 2020-07-29 ノヴォ ノルディスク アー／エス Ｇｌｐ−１誘導体及びその使用
US10392428B2 (en) 2014-12-17 2019-08-27 Novo Nordisk A/S GLP-1 derivatives and uses thereof
HK1252425A1 (zh) 2015-06-05 2019-05-24 Vertex Pharmaceuticals Incorporated 用於治疗脱髓鞘疾病的三唑类药物
PL3393496T3 (pl) 2015-12-23 2024-04-22 The Johns Hopkins University Długo działający agonista glp-1r jako terapia stanów neurologicznych i neurodegeneracyjnych
CN106928343A (zh) * 2015-12-30 2017-07-07 深圳翰宇药业股份有限公司 索玛鲁肽的制备方法
ES2835033T3 (es) * 2016-03-03 2021-06-21 Novo Nordisk As Derivados de GLP-1 y sus usos
WO2018106646A1 (en) 2016-12-06 2018-06-14 Vertex Pharmaceuticals Incorporated Aminotriazoles for the treatment of demyelinating diseases
WO2018106643A1 (en) 2016-12-06 2018-06-14 Vertex Pharmaceuticals Incorporated Heterocyclic azoles for the treatment of demyelinating diseases
WO2018106641A1 (en) 2016-12-06 2018-06-14 Vertex Pharmaceuticals Incorporated Pyrazoles for the treatment of demyelinating diseases
WO2018113340A1 (zh) * 2016-12-20 2018-06-28 中国药科大学 多肽p11及其用途
ES2980707T3 (es) 2018-04-05 2024-10-02 Sun Pharmaceutical Ind Ltd Nuevos análogos de GLP-1
US11753455B2 (en) * 2018-06-21 2023-09-12 Novo Nordisk A/S Compounds for treatment of obesity
KR20210081389A (ko) * 2018-10-22 2021-07-01 얀센 파마슈티카 엔.브이. 글루카곤 유사 펩티드 1(glp1)-성장 분화 인자 15(gdf15) 융합 단백질 및 이의 용도
JP7422754B2 (ja) * 2018-10-26 2024-01-26 ノヴォ ノルディスク アー／エス 安定性セマグルチド組成物およびその使用
WO2020118843A1 (zh) * 2018-12-12 2020-06-18 四川利通科创生物医药科技有限公司 一种glp-1突变体及其制备方法和用途
CN110590934B (zh) * 2019-09-25 2020-12-08 北京乐普医药科技有限公司 一种glp-1化合物
CN111253475B (zh) * 2020-02-18 2021-03-09 江苏诺泰澳赛诺生物制药股份有限公司 Glp-1激动多肽化合物及其盐与合成方法及用途
AR122579A1 (es) * 2020-06-12 2022-09-21 Lilly Co Eli Proceso para preparar un agonista dual glp-1 / glucagón
JP2023545684A (ja) 2020-09-30 2023-10-31 ベイジン キューエル バイオファーマシューティカル カンパニー，リミテッド ポリペプチドコンジュゲートおよび使用の方法
TW202440619A (zh) 2020-12-18 2024-10-16 丹麥商諾佛 儂迪克股份有限公司 Glp-1及澱粉素受體之共促效劑
EP4323413A4 (en) 2022-03-30 2025-10-15 Beijing Ql Biopharmaceutical Co Ltd LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF
CN117049964A (zh) * 2023-07-25 2023-11-14 杭州诺澳生物医药科技有限公司 一种脂肪二酸单叔丁酯制备工艺
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