CN1052512C - 生产2-酮基-l-古洛糖酸或其盐的方法 - Google Patents

生产2-酮基-l-古洛糖酸或其盐的方法 Download PDF

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Publication number
CN1052512C
CN1052512C CN92104573A CN92104573A CN1052512C CN 1052512 C CN1052512 C CN 1052512C CN 92104573 A CN92104573 A CN 92104573A CN 92104573 A CN92104573 A CN 92104573A CN 1052512 C CN1052512 C CN 1052512C
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CN
China
Prior art keywords
gluconobacter
microorganism
keto
gulonic acid
ifo
Prior art date
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Expired - Lifetime
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CN92104573A
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English (en)
Chinese (zh)
Other versions
CN1067681A (zh
Inventor
立夫星埜
节子尾岛
昭秀杉泽
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D Sm Ip Assets Ltd
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F Hoffmann La Roche AG
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Publication of CN1067681A publication Critical patent/CN1067681A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/02—Acetobacter
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/823—Acetobacter

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN92104573A 1991-06-13 1992-06-12 生产2-酮基-l-古洛糖酸或其盐的方法 Expired - Lifetime CN1052512C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP91810451.4 1991-06-13
EP91810451 1991-06-13

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN97110732A Division CN1181423A (zh) 1991-06-13 1997-04-15 生产2－酮基－l－古洛糖酸或其盐的方法

Publications (2)

Publication Number Publication Date
CN1067681A CN1067681A (zh) 1993-01-06
CN1052512C true CN1052512C (zh) 2000-05-17

Family

ID=8208850

Family Applications (2)

Application Number Title Priority Date Filing Date
CN92104573A Expired - Lifetime CN1052512C (zh) 1991-06-13 1992-06-12 生产2-酮基-l-古洛糖酸或其盐的方法
CN97110732A Pending CN1181423A (zh) 1991-06-13 1997-04-15 生产2－酮基－l－古洛糖酸或其盐的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN97110732A Pending CN1181423A (zh) 1991-06-13 1997-04-15 生产2－酮基－l－古洛糖酸或其盐的方法

Country Status (10)

Country Link
US (1) US5312741A (enExample)
EP (1) EP0518136B1 (enExample)
JP (1) JP3192487B2 (enExample)
CN (2) CN1052512C (enExample)
AT (1) ATE157400T1 (enExample)
DE (1) DE69221777T2 (enExample)
DK (1) DK0518136T3 (enExample)
HR (1) HRP930952B1 (enExample)
RU (1) RU2102481C1 (enExample)
YU (1) YU61392A (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL104419A0 (en) * 1992-01-24 1993-05-13 Fmc Corp Insecticidally effective peptides
US5437989A (en) * 1992-12-30 1995-08-01 Hoffmann-La Roche Inc. Alcohol/aldehyde dehydrogenase from Gluconobacter oxydans DSM 4025 FERM BP-3812
CN1080761C (zh) * 1993-12-24 2002-03-13 Basf公司 2－酮基－l－古洛糖酸的改良性生产方法
WO1995023220A1 (en) * 1994-02-25 1995-08-31 Fujisawa Pharmaceutical Co., Ltd. Process for producing 2-keto-l-gulonic acid
US5776742A (en) * 1996-02-19 1998-07-07 Roche Vitamins Inc. Aldehyde dehydrogenase enzyme
US5834231A (en) * 1996-10-24 1998-11-10 Archer Daniels Midland Co. Bacterial strains and use thereof in fermentation process for 2-keto-L-gulonic acid production
EP0869175B1 (en) * 1997-04-04 2011-03-09 DSM IP Assets B.V. Cytochrome C and its gene
US6238897B1 (en) * 1998-07-17 2001-05-29 Roche Vitamins Inc. Continuous process for producing 2-keto-L-gulonic acid
EP0972843A1 (en) * 1998-07-17 2000-01-19 F. Hoffmann-La Roche Ag Continuous fermentation process
EP1112344A2 (en) 1998-09-11 2001-07-04 Archer-Daniels-Midland Company Bacterial strains for the production of 2-keto-l-gulonic acid
DE19907115A1 (de) * 1999-02-19 2000-08-24 Basf Ag Verfahren zur Herstellung von L-Sorbose
US6204040B1 (en) 1999-04-22 2001-03-20 Korea Research Institute Of Bioscience And Biotechnology Gluconobacter suboxydans sorbitol dehydrogenase, genes and methods of use thereof
US6153791A (en) * 1999-08-02 2000-11-28 Archer-Daniels-Midland Company Process for purifying 2-keto-L-gulonic acid
US6902917B1 (en) 1999-08-03 2005-06-07 Archer-Daniels-Midland Company Process for recovery of organic acids from fermentration broths
US7033824B2 (en) 2000-04-05 2006-04-25 Archer-Daniels-Midland Company Ketogulonigenium shuttle vectors
US20020006665A1 (en) * 2000-04-05 2002-01-17 D'elia John Ketogulonigenium endogenous plasmids
US6387654B1 (en) 2000-05-04 2002-05-14 Archer-Daniels-Midland Company Bacterial strains and fermentation processes for the production of 2-keto-l-gulonic acid
GB0119864D0 (en) * 2001-08-15 2001-10-10 Cerestar Holding Bv Process for the manufacture of 2-keto-L-gulonic acid
AU2003280338A1 (en) 2002-09-27 2004-04-19 Dsm Ip Assets B.V. Process for producing vitamin c
AU2003283253A1 (en) * 2002-09-27 2004-04-19 Dsm Ip Assets B.V. Production of 2-kga
WO2004029268A1 (en) * 2002-09-27 2004-04-08 Dsm Ip Assets B.V. Microbial production of vitamin c
WO2004029262A2 (en) * 2002-09-27 2004-04-08 Dsm Ip Assets B.V. Production of 2 - keto - l - gulonic acd
CN102757928B (zh) * 2012-08-09 2014-04-16 山东天力药业有限公司 一种2-酮基-l-古龙酸高耐受型氧化葡糖酸杆菌及其在维生素c发酵生产中的应用
WO2016141148A1 (en) * 2015-03-05 2016-09-09 Bp Corporation North America Inc. Synthesis of furans from sugars via keto intermediates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5021559B2 (enExample) * 1973-03-22 1975-07-23
EP0213591B1 (en) * 1985-08-28 1992-03-25 F. Hoffmann-La Roche Ag Process for the manufacture of keto gulonic acid
DK171869B1 (da) * 1985-10-22 1997-07-21 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-keto-L-gulonsyre samt biologisk ren mikroorganismekultur til anvendelse ved fremgangsmåden
US4933289A (en) * 1986-06-05 1990-06-12 Takeda Chemical Industries, Ltd. Biologically pure cultures of Pseudomonas sorbosoxidans useful for producing 2-keto-L-gulonic acid
JPH0795957B2 (ja) * 1986-06-05 1995-10-18 武田薬品工業株式会社 ２−ケト−ｌ−グロン酸の製造法
US4935359A (en) * 1987-02-07 1990-06-19 Institute Of Microbiology Fermentation process
DK173507B1 (da) * 1988-09-30 2001-01-15 Hoffmann La Roche Fremgangsmåde til fremstilling af 2-keto-L-gulonsyre

Also Published As

Publication number Publication date
DE69221777T2 (de) 1998-01-29
HRP930952A2 (en) 1995-12-31
EP0518136B1 (en) 1997-08-27
ATE157400T1 (de) 1997-09-15
HRP930952B1 (en) 2000-06-30
EP0518136A3 (enExample) 1994-03-30
DE69221777D1 (de) 1997-10-02
CN1181423A (zh) 1998-05-13
US5312741A (en) 1994-05-17
JPH05317062A (ja) 1993-12-03
EP0518136A2 (en) 1992-12-16
JP3192487B2 (ja) 2001-07-30
DK0518136T3 (da) 1997-12-22
YU61392A (sh) 1994-11-15
CN1067681A (zh) 1993-01-06
RU2102481C1 (ru) 1998-01-20

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C15 Extension of patent right duration from 15 to 20 years for appl. with date before 31.12.1992 and still valid on 11.12.2001 (patent law change 1993)
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Owner name: DSM IP ASSET CO., LTD.

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