DE69221777T2 - Fermentationsverfahren zur Herstellung von 2-Keto-L-Gulonsäure - Google Patents

Fermentationsverfahren zur Herstellung von 2-Keto-L-Gulonsäure

Info

Publication number
DE69221777T2
DE69221777T2 DE69221777T DE69221777T DE69221777T2 DE 69221777 T2 DE69221777 T2 DE 69221777T2 DE 69221777 T DE69221777 T DE 69221777T DE 69221777 T DE69221777 T DE 69221777T DE 69221777 T2 DE69221777 T2 DE 69221777T2
Authority
DE
Germany
Prior art keywords
keto
production
gulonic acid
fermentation process
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69221777T
Other languages
English (en)
Other versions
DE69221777D1 (de
Inventor
Tatsuo Hoshino
Setuko Ojima
Teruhide Sugisawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE69221777D1 publication Critical patent/DE69221777D1/de
Publication of DE69221777T2 publication Critical patent/DE69221777T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/02—Acetobacter
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/823—Acetobacter

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE69221777T 1991-06-13 1992-05-29 Fermentationsverfahren zur Herstellung von 2-Keto-L-Gulonsäure Expired - Lifetime DE69221777T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91810451 1991-06-13

Publications (2)

Publication Number Publication Date
DE69221777D1 DE69221777D1 (de) 1997-10-02
DE69221777T2 true DE69221777T2 (de) 1998-01-29

Family

ID=8208850

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69221777T Expired - Lifetime DE69221777T2 (de) 1991-06-13 1992-05-29 Fermentationsverfahren zur Herstellung von 2-Keto-L-Gulonsäure

Country Status (10)

Country Link
US (1) US5312741A (de)
EP (1) EP0518136B1 (de)
JP (1) JP3192487B2 (de)
CN (2) CN1052512C (de)
AT (1) ATE157400T1 (de)
DE (1) DE69221777T2 (de)
DK (1) DK0518136T3 (de)
HR (1) HRP930952B1 (de)
RU (1) RU2102481C1 (de)
YU (1) YU61392A (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL104419A0 (en) * 1992-01-24 1993-05-13 Fmc Corp Insecticidally effective peptides
US5437989A (en) * 1992-12-30 1995-08-01 Hoffmann-La Roche Inc. Alcohol/aldehyde dehydrogenase from Gluconobacter oxydans DSM 4025 FERM BP-3812
CN1080761C (zh) * 1993-12-24 2002-03-13 Basf公司 2－酮基－l－古洛糖酸的改良性生产方法
US5834263A (en) * 1994-02-25 1998-11-10 Fujisawa Pharmaceutical Co., Ltd. Method for producing 2-keto-L-gulonic acid
US5776742A (en) * 1996-02-19 1998-07-07 Roche Vitamins Inc. Aldehyde dehydrogenase enzyme
US5834231A (en) * 1996-10-24 1998-11-10 Archer Daniels Midland Co. Bacterial strains and use thereof in fermentation process for 2-keto-L-gulonic acid production
EP0869175B1 (de) * 1997-04-04 2011-03-09 DSM IP Assets B.V. Cytochrom C und dessen Gen
CA2277539A1 (en) * 1998-07-17 2000-01-17 F. Hoffmann-La Roche Ag Continuous fermentation process
EP0972843A1 (de) * 1998-07-17 2000-01-19 F. Hoffmann-La Roche Ag Kontinuierliches Fermentationsverfahren
EP1112344A2 (de) 1998-09-11 2001-07-04 Archer-Daniels-Midland Company Bakterienstämme für die herstellung von 2-keto-l-gulonsäure
DE19907115A1 (de) * 1999-02-19 2000-08-24 Basf Ag Verfahren zur Herstellung von L-Sorbose
US6204040B1 (en) 1999-04-22 2001-03-20 Korea Research Institute Of Bioscience And Biotechnology Gluconobacter suboxydans sorbitol dehydrogenase, genes and methods of use thereof
US6153791A (en) * 1999-08-02 2000-11-28 Archer-Daniels-Midland Company Process for purifying 2-keto-L-gulonic acid
US6902917B1 (en) * 1999-08-03 2005-06-07 Archer-Daniels-Midland Company Process for recovery of organic acids from fermentration broths
AU2001253162A1 (en) 2000-04-05 2001-10-23 Archer-Daniels-Midland Company Ketogulonigenium shuttle vectors
US20020006665A1 (en) 2000-04-05 2002-01-17 D'elia John Ketogulonigenium endogenous plasmids
US6387654B1 (en) 2000-05-04 2002-05-14 Archer-Daniels-Midland Company Bacterial strains and fermentation processes for the production of 2-keto-l-gulonic acid
GB0119864D0 (en) * 2001-08-15 2001-10-10 Cerestar Holding Bv Process for the manufacture of 2-keto-L-gulonic acid
AU2003270233A1 (en) * 2002-09-27 2004-04-19 Dsm Ip Assets B.V. Production of 2 - keto - l - gulonic acd
AU2003270234A1 (en) * 2002-09-27 2004-04-19 Dsm Ip Assets B.V. Microbial production of vitamin c
AU2003283253A1 (en) * 2002-09-27 2004-04-19 Dsm Ip Assets B.V. Production of 2-kga
AU2003280338A1 (en) * 2002-09-27 2004-04-19 Dsm Ip Assets B.V. Process for producing vitamin c
CN102757928B (zh) * 2012-08-09 2014-04-16 山东天力药业有限公司 一种2-酮基-l-古龙酸高耐受型氧化葡糖酸杆菌及其在维生素c发酵生产中的应用
WO2016141148A1 (en) * 2015-03-05 2016-09-09 Bp Corporation North America Inc. Synthesis of furans from sugars via keto intermediates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5021559B2 (de) * 1973-03-22 1975-07-23
DE3684533D1 (de) * 1985-08-28 1992-04-30 Hoffmann La Roche Verfahren zur herstellung von ketogulonsaeure.
DK171869B1 (da) * 1985-10-22 1997-07-21 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-keto-L-gulonsyre samt biologisk ren mikroorganismekultur til anvendelse ved fremgangsmåden
US4933289A (en) * 1986-06-05 1990-06-12 Takeda Chemical Industries, Ltd. Biologically pure cultures of Pseudomonas sorbosoxidans useful for producing 2-keto-L-gulonic acid
JPH0795957B2 (ja) * 1986-06-05 1995-10-18 武田薬品工業株式会社 ２−ケト−ｌ−グロン酸の製造法
US4935359A (en) * 1987-02-07 1990-06-19 Institute Of Microbiology Fermentation process
DK173507B1 (da) * 1988-09-30 2001-01-15 Hoffmann La Roche Fremgangsmåde til fremstilling af 2-keto-L-gulonsyre

Also Published As

Publication number Publication date
JPH05317062A (ja) 1993-12-03
CN1067681A (zh) 1993-01-06
YU61392A (sh) 1994-11-15
EP0518136B1 (de) 1997-08-27
JP3192487B2 (ja) 2001-07-30
ATE157400T1 (de) 1997-09-15
HRP930952A2 (en) 1995-12-31
CN1052512C (zh) 2000-05-17
DK0518136T3 (da) 1997-12-22
US5312741A (en) 1994-05-17
EP0518136A2 (de) 1992-12-16
RU2102481C1 (ru) 1998-01-20
HRP930952B1 (en) 2000-06-30
EP0518136A3 (de) 1994-03-30
CN1181423A (zh) 1998-05-13
DE69221777D1 (de) 1997-10-02

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