CN105213946A - 一种治疗便秘的药物及其制备方法 - Google Patents
一种治疗便秘的药物及其制备方法 Download PDFInfo
- Publication number
- CN105213946A CN105213946A CN201510748617.6A CN201510748617A CN105213946A CN 105213946 A CN105213946 A CN 105213946A CN 201510748617 A CN201510748617 A CN 201510748617A CN 105213946 A CN105213946 A CN 105213946A
- Authority
- CN
- China
- Prior art keywords
- grams
- gram
- radix
- fructus
- rhizoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 39
- 206010010774 Constipation Diseases 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 210000000582 Semen Anatomy 0.000 claims abstract description 35
- 241000218236 Cannabis Species 0.000 claims abstract description 12
- 241000628997 Flos Species 0.000 claims abstract description 11
- 240000008397 Ganoderma lucidum Species 0.000 claims abstract description 11
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims abstract description 11
- 239000009636 Huang Qi Substances 0.000 claims abstract description 11
- 239000010135 fructus aurantii immaturus Substances 0.000 claims abstract description 11
- 238000004140 cleaning Methods 0.000 claims description 40
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances data:image/svg+xml;base64,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 data:image/svg+xml;base64,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 O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 26
- 238000005202 decontamination Methods 0.000 claims description 20
- 230000003588 decontaminative Effects 0.000 claims description 20
- 239000012535 impurity Substances 0.000 claims description 20
- 229940079593 drugs Drugs 0.000 claims description 17
- 241000005787 Cistanche Species 0.000 claims description 13
- 238000009835 boiling Methods 0.000 claims description 10
- 210000000080 chela (arthropods) Anatomy 0.000 claims description 7
- 235000015099 wheat brans Nutrition 0.000 claims description 6
- 230000003203 everyday Effects 0.000 claims description 5
- 238000005520 cutting process Methods 0.000 claims description 4
- 239000007921 spray Substances 0.000 claims description 4
- 235000013372 meat Nutrition 0.000 claims description 3
- 241000266855 Astragalus mongholicus Species 0.000 claims description 2
- 235000006533 astragalus Nutrition 0.000 claims description 2
- 235000019504 cigarettes Nutrition 0.000 claims description 2
- 235000013399 edible fruits Nutrition 0.000 claims description 2
- 239000000284 extract Substances 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims description 2
- 239000003205 fragrance Substances 0.000 claims description 2
- 238000002386 leaching Methods 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 239000002245 particle Substances 0.000 claims description 2
- 239000002994 raw material Substances 0.000 claims description 2
- 230000001429 stepping Effects 0.000 claims description 2
- 238000003756 stirring Methods 0.000 claims description 2
- 210000004369 Blood Anatomy 0.000 abstract description 23
- 239000008280 blood Substances 0.000 abstract description 23
- 210000003734 Kidney Anatomy 0.000 abstract description 14
- 230000001105 regulatory Effects 0.000 abstract description 9
- 230000017531 blood circulation Effects 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 8
- 231100000765 Toxin Toxicity 0.000 abstract description 3
- 230000000968 intestinal Effects 0.000 abstract description 3
- 239000003053 toxin Substances 0.000 abstract description 3
- 239000000796 flavoring agent Substances 0.000 description 30
- 235000019634 flavors Nutrition 0.000 description 30
- 210000004185 Liver Anatomy 0.000 description 20
- 210000000952 Spleen Anatomy 0.000 description 20
- 208000002193 Pain Diseases 0.000 description 16
- 235000009508 confectionery Nutrition 0.000 description 15
- 210000002784 Stomach Anatomy 0.000 description 14
- 206010062717 Increased upper airway secretion Diseases 0.000 description 12
- 210000004072 Lung Anatomy 0.000 description 11
- 210000001015 Abdomen Anatomy 0.000 description 10
- 206010011224 Cough Diseases 0.000 description 10
- 210000002429 large intestine Anatomy 0.000 description 9
- 206010037660 Pyrexia Diseases 0.000 description 8
- 210000000038 chest Anatomy 0.000 description 8
- 235000019525 fullness Nutrition 0.000 description 8
- 208000001848 Dysentery Diseases 0.000 description 7
- 206010030113 Oedema Diseases 0.000 description 7
- 231100000614 Poison Toxicity 0.000 description 7
- 230000001717 pathogenic Effects 0.000 description 7
- 206010000087 Abdominal pain upper Diseases 0.000 description 6
- 206010007247 Carbuncle Diseases 0.000 description 6
- 208000002173 Dizziness Diseases 0.000 description 6
- 206010027327 Menstrual disease Diseases 0.000 description 6
- 206010027514 Metrorrhagia Diseases 0.000 description 6
- 230000002522 swelling Effects 0.000 description 6
- 208000006820 Arthralgia Diseases 0.000 description 5
- 210000000936 Intestines Anatomy 0.000 description 5
- 206010068760 Ulcers Diseases 0.000 description 5
- 239000002253 acid Substances 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 235000013305 food Nutrition 0.000 description 5
- 201000007227 lymph node tuberculosis Diseases 0.000 description 5
- 230000014759 maintenance of location Effects 0.000 description 5
- 244000052769 pathogens Species 0.000 description 5
- 231100000397 ulcer Toxicity 0.000 description 5
- 208000006673 Asthma Diseases 0.000 description 4
- 210000000481 Breast Anatomy 0.000 description 4
- 206010012735 Diarrhoea Diseases 0.000 description 4
- 210000000232 Gallbladder Anatomy 0.000 description 4
- 210000002216 Heart Anatomy 0.000 description 4
- 230000002269 spontaneous Effects 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 231100000331 toxic Toxicity 0.000 description 4
- 239000003440 toxic substance Substances 0.000 description 4
- 206010000077 Abdominal mass Diseases 0.000 description 3
- 206010001928 Amenorrhoea Diseases 0.000 description 3
- 206010016256 Fatigue Diseases 0.000 description 3
- 206010019233 Headache Diseases 0.000 description 3
- 206010067171 Regurgitation Diseases 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 3
- 230000003187 abdominal Effects 0.000 description 3
- 230000002411 adverse Effects 0.000 description 3
- 201000000736 amenorrhea Diseases 0.000 description 3
- 231100000540 amenorrhea Toxicity 0.000 description 3
- 230000001396 anti-anti-diuretic Effects 0.000 description 3
- 230000013872 defecation Effects 0.000 description 3
- 201000008286 diarrhea Diseases 0.000 description 3
- 230000001882 diuretic Effects 0.000 description 3
- 239000002934 diuretic Substances 0.000 description 3
- 201000006549 dyspepsia Diseases 0.000 description 3
- 230000003419 expectorant Effects 0.000 description 3
- 239000003172 expectorant agent Substances 0.000 description 3
- 231100000869 headache Toxicity 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 230000001737 promoting Effects 0.000 description 3
- 230000001225 therapeutic Effects 0.000 description 3
- 230000035922 thirst Effects 0.000 description 3
- 230000002588 toxic Effects 0.000 description 3
- 206010000060 Abdominal distension Diseases 0.000 description 2
- 206010063409 Acarodermatitis Diseases 0.000 description 2
- 206010003549 Asthenia Diseases 0.000 description 2
- 206010010741 Conjunctivitis Diseases 0.000 description 2
- 206010011878 Deafness Diseases 0.000 description 2
- 206010061428 Decreased appetite Diseases 0.000 description 2
- 241000668709 Dipterocarpus costatus Species 0.000 description 2
- 208000000059 Dyspnea Diseases 0.000 description 2
- 206010013975 Dyspnoeas Diseases 0.000 description 2
- 206010013990 Dysuria Diseases 0.000 description 2
- 208000001780 Epistaxis Diseases 0.000 description 2
- 206010016286 Febrile disease Diseases 0.000 description 2
- 206010017553 Furuncle Diseases 0.000 description 2
- 206010018987 Haemorrhage Diseases 0.000 description 2
- 208000006454 Hepatitis Diseases 0.000 description 2
- 210000001624 Hip Anatomy 0.000 description 2
- 208000008454 Hyperhidrosis Diseases 0.000 description 2
- 206010021118 Hypotonia Diseases 0.000 description 2
- 206010022437 Insomnia Diseases 0.000 description 2
- 206010023126 Jaundice Diseases 0.000 description 2
- 208000004396 Mastitis Diseases 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 208000005687 Scabies Diseases 0.000 description 2
- 241000447727 Scabies Species 0.000 description 2
- 206010042674 Swelling Diseases 0.000 description 2
- 206010046814 Uterine prolapse Diseases 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 201000004484 acute conjunctivitis Diseases 0.000 description 2
- 238000004220 aggregation Methods 0.000 description 2
- 230000002776 aggregation Effects 0.000 description 2
- 230000001166 anti-perspirant Effects 0.000 description 2
- 239000003213 antiperspirant Substances 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019658 bitter taste Nutrition 0.000 description 2
- 230000034002 defecation rhythm Effects 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 231100000283 hepatitis Toxicity 0.000 description 2
- 210000004914 menses Anatomy 0.000 description 2
- 230000003020 moisturizing Effects 0.000 description 2
- 230000000414 obstructive Effects 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 230000025627 positive regulation of urine volume Effects 0.000 description 2
- 230000003014 reinforcing Effects 0.000 description 2
- 231100000486 side effect Toxicity 0.000 description 2
- 230000035900 sweating Effects 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- 231100000820 toxicity test Toxicity 0.000 description 2
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010001093 Acute tonsillitis Diseases 0.000 description 1
- 206010002153 Anal fissure Diseases 0.000 description 1
- 206010002156 Anal fistula Diseases 0.000 description 1
- 206010002383 Angina pectoris Diseases 0.000 description 1
- 206010003011 Appendicitis Diseases 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 208000002894 Beriberi Diseases 0.000 description 1
- 206010006451 Bronchitis Diseases 0.000 description 1
- 206010009346 Clonus Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010012218 Delirium Diseases 0.000 description 1
- 208000010228 Erectile Dysfunction Diseases 0.000 description 1
- 206010015137 Eructation Diseases 0.000 description 1
- 210000003414 Extremities Anatomy 0.000 description 1
- 206010015958 Eye pain Diseases 0.000 description 1
- 210000003608 Feces Anatomy 0.000 description 1
- 208000009531 Fissure in Ano Diseases 0.000 description 1
- 208000007882 Gastritis Diseases 0.000 description 1
- 206010018045 Gastroptosis Diseases 0.000 description 1
- 208000007565 Gingivitis Diseases 0.000 description 1
- 206010018830 Haematemesis Diseases 0.000 description 1
- 208000002287 Hemorrhoids Diseases 0.000 description 1
- 206010019641 Hepatic cirrhosis Diseases 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 210000003026 Hypopharynx Anatomy 0.000 description 1
- 206010022114 Injury Diseases 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- 208000001083 Kidney Disease Diseases 0.000 description 1
- 210000003127 Knee Anatomy 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 206010025421 Macule Diseases 0.000 description 1
- 210000003205 Muscles Anatomy 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010029149 Nephropathy Diseases 0.000 description 1
- 206010029151 Nephropathy Diseases 0.000 description 1
- 208000001140 Night Blindness Diseases 0.000 description 1
- 206010029410 Night sweats Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-N Picric acid Chemical compound data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' viewBox='0 0 300 300'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300.0' height='300.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 237.8,148.0 L 221.6,148.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 221.6,148.0 L 205.4,148.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 205.4,148.0 L 180.7,190.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 193.1,149.5 L 175.8,179.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-12 atom-1' d='M 180.7,105.2 L 205.4,148.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 180.7,190.8 L 188.5,204.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 188.5,204.4 L 196.3,217.9' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-2 atom-6' d='M 180.7,190.8 L 131.2,190.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 194.0,253.3 L 191.7,257.3' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 191.7,257.3 L 189.4,261.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 230.6,238.6 L 234.5,238.6' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 234.5,238.6 L 238.4,238.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 230.6,228.7 L 234.5,228.7' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 234.5,228.7 L 238.4,228.7' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 131.2,190.8 L 106.5,148.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 136.1,179.5 L 118.8,149.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 106.5,148.0 L 94.4,148.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 94.4,148.0 L 82.3,148.0' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-7 atom-11' d='M 106.5,148.0 L 131.2,105.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 48.0,132.3 L 45.7,128.4' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 45.7,128.4 L 43.5,124.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 41.4,165.2 L 39.1,169.2' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 39.1,169.2 L 36.8,173.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 50.0,170.2 L 47.7,174.2' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 47.7,174.2 L 45.4,178.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 131.2,105.2 L 180.7,105.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 138.7,115.1 L 173.3,115.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 180.7,105.2 L 187.4,93.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 187.4,93.6 L 194.0,82.1' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 230.6,62.4 L 234.5,62.4' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 234.5,62.4 L 238.4,62.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 200.6,44.2 L 198.3,40.3' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 198.3,40.3 L 196.1,36.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 192.0,49.1 L 189.8,45.2' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 189.8,45.2 L 187.5,41.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='248.9' y='157.9' class='atom-0' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='262.6' y='157.9' class='atom-0' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='199.5' y='243.5' class='atom-3' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='213.1' y='235.6' class='atom-3' style='font-size:13px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >+</text>
<text x='174.8' y='286.4' class='atom-4' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='188.4' y='278.5' class='atom-4' style='font-size:13px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='248.9' y='243.5' class='atom-5' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='51.1' y='157.9' class='atom-8' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='64.8' y='150.0' class='atom-8' style='font-size:13px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >+</text>
<text x='26.4' y='115.1' class='atom-9' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='40.1' y='107.2' class='atom-9' style='font-size:13px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='26.4' y='200.7' class='atom-10' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='199.5' y='72.3' class='atom-13' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='213.1' y='64.4' class='atom-13' style='font-size:13px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >+</text>
<text x='248.9' y='72.3' class='atom-14' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='262.6' y='64.4' class='atom-14' style='font-size:13px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='174.8' y='29.5' class='atom-15' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' viewBox='0 0 85 85'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85.0' height='85.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 69.6,41.4 L 63.6,41.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 63.6,41.4 L 57.7,41.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 57.7,41.4 L 50.7,53.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 54.2,41.9 L 49.3,50.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-12 atom-1' d='M 50.7,29.3 L 57.7,41.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 50.7,53.6 L 53.6,58.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 53.6,58.6 L 56.5,63.6' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-2 atom-6' d='M 50.7,53.6 L 36.7,53.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 55.8,69.1 L 53.8,72.4' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 53.8,72.4 L 51.9,75.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 62.3,67.1 L 66.0,67.1' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 66.0,67.1 L 69.7,67.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 62.3,64.3 L 66.0,64.3' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 66.0,64.3 L 69.7,64.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 36.7,53.6 L 29.7,41.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 38.1,50.4 L 33.2,41.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 29.7,41.4 L 25.0,41.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 25.0,41.4 L 20.3,41.4' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-7 atom-11' d='M 29.7,41.4 L 36.7,29.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 14.4,39.3 L 12.5,35.9' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 12.5,35.9 L 10.6,32.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 12.5,44.1 L 10.6,47.5' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 10.6,47.5 L 8.6,50.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 15.0,45.5 L 13.0,48.9' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 13.0,48.9 L 11.1,52.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 36.7,29.3 L 50.7,29.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 38.8,32.1 L 48.6,32.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 50.7,29.3 L 53.2,24.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 53.2,24.9 L 55.8,20.5' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 62.3,17.2 L 66.0,17.2' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 66.0,17.2 L 69.7,17.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 57.7,14.3 L 55.7,11.0' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 55.7,11.0 L 53.8,7.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 55.2,15.7 L 53.3,12.4' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 53.3,12.4 L 51.4,9.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='69.9' y='44.4' class='atom-0' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='74.0' y='44.4' class='atom-0' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='55.9' y='68.7' class='atom-3' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='60.0' y='66.3' class='atom-3' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >+</text>
<text x='48.9' y='80.8' class='atom-4' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='53.0' y='78.4' class='atom-4' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='69.9' y='68.7' class='atom-5' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='13.9' y='44.4' class='atom-8' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='18.0' y='42.0' class='atom-8' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >+</text>
<text x='6.9' y='32.3' class='atom-9' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='11.0' y='29.9' class='atom-9' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='6.9' y='56.6' class='atom-10' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='55.9' y='20.2' class='atom-13' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='60.0' y='17.8' class='atom-13' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >+</text>
<text x='69.9' y='20.2' class='atom-14' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='74.0' y='17.8' class='atom-14' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='48.9' y='8.0' class='atom-15' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
</svg>
 OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 description 1
- 206010036018 Pollakiuria Diseases 0.000 description 1
- 208000008425 Protein Deficiency Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010057071 Rectal tenesmus Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 206010043458 Thirst Diseases 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 206010046577 Urinary tract infection Diseases 0.000 description 1
- 210000002700 Urine Anatomy 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 1
- 230000003213 activating Effects 0.000 description 1
- 201000005661 acute cystitis Diseases 0.000 description 1
- 230000000240 adjuvant Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 201000010188 anus disease Diseases 0.000 description 1
- 231100000319 bleeding Toxicity 0.000 description 1
- 230000000740 bleeding Effects 0.000 description 1
- 201000004569 blindness Diseases 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 201000001352 cholecystitis Diseases 0.000 description 1
- 230000001684 chronic Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000002354 daily Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 201000000297 erysipelas Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound data:image/svg+xml;base64,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 data:image/svg+xml;base64,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 CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 230000001605 fetal Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000002650 habitual Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 201000004044 liver cirrhosis Diseases 0.000 description 1
- 201000003265 lymphadenitis Diseases 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 230000001617 migratory Effects 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 229940114148 picric acid Drugs 0.000 description 1
- 230000001047 pyretic Effects 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 230000004206 stomach function Effects 0.000 description 1
- 229950002929 trinitrophenol Drugs 0.000 description 1
- 201000002327 urinary tract obstruction Diseases 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Abstract
本发明公开了一种治疗便秘的药物及其制备方法，其主要是由太子参、黄芪、灵芝草、当归、川芎、熟地黄、砂仁、山药、白芍、白术、青蒿、香附、连翘、枳实、决明子、瓜蒌、佛手钳、柴胡、厚朴、山楂、郁李仁、火麻仁、金银花、瓦楞子、乌贼鱼肉按一定重量配比制备而成，本发明药物具有补肾益精，补血和血，顺气导滞，清热排毒，润燥滑肠的功能，用于治疗便秘见效快、疗效好，不复发。
Description
技术领域
[0001] 本发明涉及一种治疗便秘的药物及其制备方法，属中药领域。 技术背景
[0002] 便秘是指一种大肠病证，由于大肠传导功能失常，导致大便排出困难，排便时间或 排便间隔时间延长。中医则认为便秘与脾胃受寒，肠中有热和肾病有关。由于西药治疗副 作用大，因此人们对有效治疗便秘的中药药物存在极大的需求，至今为止，还没有发现关于 本发明的有关报道。
发明内容
[0003] 本发明人依据中医理论的研究和临床试验的反复验证，终于找到了有效治疗便秘 的药物，从而完成了本发明。
[0004] 本发明的目的就是提供一种有效治疗便秘的中药组合药物。
[0005] 本发明的另一目的就是提供了该中药组合药物的制备方法。
[0006] 本发明药物是选择太子参、黄芪、灵芝草、当归、川芎、熟地黄、砂仁、山药、白芍、白 术、青蒿、香附、连翘、枳实、决明子、玄参、瓜蒌、大黄、肉苁蓉、杏仁、佛手钳、柴胡、厚朴、山 楂、郁李仁、火麻仁、金银花、蒲公英、瓦楞子、乌贼鱼肉药物进行组合制备的，将这些药物组 合使得各药物功效产生协同作用，从而能够有效治疗便秘。其中，选用太子参是因为其性味 甘苦，微温，入心、脾、肺三经，有补肺、健脾的功能，治肺虚咳嗽，脾虚食少，心悸且汗，精神 疲乏。选用黄芪是因为其性味甘，微温，入肺、脾经，生用有益卫固表，利水消肿，托毒，生肌 的功能，治自汗，盗汗，血痹，浮肿，痈疽不溃或溃久敛；炙用有补中益的功能，治内伤劳倦， 脾虚泄泻，脱肛，气虚血脱，崩带及一切气衰血虚之症。选用灵芝草是因为其性味甘，平，入 心、肺、肝、肾经，有补气安神，止咳平喘的功能，治虚劳，咳嗽，气喘，失眠，消化不良。选用当 归是因为其性味甘辛，温，入心、肝、脾经，有补血和血，调经止痛，润燥滑肠的功能，治月经 不调，经闭腹痛，癥瘕结聚，崩漏，血虚头痛，眩晕，痿痹，肠燥难便，赤痢后重，痈疽疮疡，金 疮，跌扑损伤。选用川芎是因为其性味辛，温，入肝、胆经，有行气开郁，祛风燥湿，活血止痛 的功能，治风冷头痛旋晕，胁痛腹疼，寒痹筋挛，经闭，难产，产后瘀阻块痛，痈疽疮疡。选用 熟地黄是因为其性味甘，微温，入肝、肾经，有滋阴，补血的功能，治阴虚血少，腰膝痿弱，劳 嗽骨蒸，遗精，崩漏，月经不调，消渴，溲数，耳聋，目昏。选用砂仁是因为其性味辛，温，入脾、 胃经，有行气调中，和胃、醒脾的功能，治腹痛痞胀，胃呆食滞，噎隔呕吐，寒泻冷痢，妊娠胎 动。选用山药是因为其性味甘，平，入肺、脾、肾经，有健脾，补肺，固肾，益精的功能，治脾虚 泄泻，久痢，虚劳咳嗽，消渴，遗精、带下，小便频数。选用白芍是因为其性味苦酸，凉，入肝、 脾经，有养血柔肝，缓中止痛，敛阴收汗的功能，治胸腹胁肋疼痛，泻痢腹痛，自汗盗汗，阴虚 发热，月经不调，崩漏，带下。选用白术是因为其性味苦甘，温，入脾、胃经，有补脾，益胃，燥 湿，和中的功能，治脾胃气弱，不思饮食，倦怠少气，虚胀，泄泻，痰饮，水肿，黄疸，湿痹，小便 不利，头晕，自汗，胎气不安。选用青蒿是因为其性味苦，微辛，寒，归入肝、胆经，有清热，解 暑，除蒸的功能，治温病，暑热，骨蒸劳热，疥疮，瘙痒。选用香附是因为其性味辛微苦干，平， 入肝、三焦经，有理气解郁，止痛调经的功能，治肝胃不和，气郁不舒，胸腹胁肋胀痛，痰饮痞 满，月经不调，崩漏带下。选用连翘是因为其性味苦，凉，入心、肝、胆经，有清热，解毒，散结， 消肿的功能，治温热，丹毒，斑疹，痈疡肿毒，瘰疬，小便淋闭。选用枳实是因为其性味苦，寒， 入脾、胃经，有破气，散痞，泻痰，消积的功能，治胸腹胀痛，胸痹，痞痛，痰癖，水肿，食积，便 秘，胃下垂，子宫下垂，脱肛。选用决明子是因为其性味苦甘，凉，入肝、肾经，有清肝，明目， 利水，通便的功能，治风热赤眼，青盲，雀目，高血压，肝炎，肝硬化腹化，习惯性便秘。选用玄 参是因为其性味苦，咸，凉，入肺、肾经，有滋阴，降火，除烦，解毒的功能，治热病烦渴，发斑， 骨蒸劳热，夜寐不宁，自汗盗汗，津伤便秘，吐血衄血，咽喉肿痛，痈肿，瘰疬。选用瓜蒌是因 为其性味甘、微苦，寒，归肺、胃、大肠经，有清热涤痰，宽胸散结，润燥滑肠的功能，治肺热咳 嗽，痰浊黄稠，胸痹心痛，结胸痞满，乳痈，肠痈，大便秘结。选用大黄是因为其性味苦、寒， 入胃、大肠、肝径，有泻热毒，破积滞，行瘀血的功能，治实热便秘，谵语发狂，食积痞满，痢疾 初起，里急后重，瘀停经闭，癥瘕积聚，时行热疫，暴眼赤痛，吐血，衄血，阳黄，水肿，淋池，溲 赤，痈疡肿毒，疔疮，汤火伤。选用肉苁蓉是因为其性味甘酸咸，温，入肾、大肠经，有补肾， 益精，润燥，清肠的功能，治男子阳痿，女子不孕，带下，血崩，腰膝冷痛，血枯便秘。选用杏 仁是因为其性味苦，温，有毒，入肺、大肠经，有祛痰止咳，平喘，润肠的功能，治外感咳嗽，喘 满，喉痹，肠燥便秘。选用佛手柑是因为其性味辛苦酸，温，入肝、胃经，有理气，化痰的功能， 治胃痛，胁胀，呕吐，噎膈，痰饮咳喘，并能解酒。选用柴胡是因为其性味苦，凉，入肝、胆经， 有和解表里，疏肝，升阳的功能，治寒热往来，胸满胁痛，口苦耳聋，头痛目眩，疟疾，下利脱 肛，月经不调，子宫下垂。选用厚朴是因为其性味苦辛，温，入脾、胃、大肠经，有温中，下气， 燥湿，消痰的功能，治胸腹痞满胀痛，反胃、呕吐，宿食不消，痰饮喘咳，寒湿泻痢。选用山楂 是因为其性味酸甘，微温，入脾、胃、肝经，有消食积，散瘀血，驱绦虫的功能，治肉积，癥瘕， 痰饮，痞满，吞酸，泻痢，肠风，腰痛，疝气，产后儿枕痛，恶露不尽，小儿乳食停滞。选用郁李 仁是因为其性味辛苦甘，平，入脾、大小肠经，有润燥，滑肠，下气，利水的功能，治大肠气滞， 燥涩不通，小便不利，大腹水肿，四肢浮肿，脚气。选用火麻仁是因为其性味甘，平，入脾、胃、 大肠经，有润燥，滑肠，通淋，活血的功能，治肠燥便秘，消渴，热淋，风痹，痢疾，月经不调，疥 疮，癣癫。选用金银花是因为其性味甘，寒，入肺、胃经，有清热，解毒的功能，治温病发热，热 毒血痢，痈疡，肿毒，瘰疬，痔漏。选用蒲公英是因为其性味苦甘，寒，入肝、胃经，有清热解 毒，利尿散结的功能，治急性乳腺炎，淋巴腺炎，瘰疬，疔毒疮肿，急性结膜炎，感冒发热，急 性扁桃体炎，急性支气管炎，胃炎，肝炎，胆囊炎，尿路感染。选用瓦楞子是因为其性味甘， 咸，平，入肝、脾经，有化痰，软坚，散瘀，消积的功能，治痰积，胃痛，嘈杂，吐酸，癥瘕，瘰疬， 牙疳。选用乌贼鱼肉是因为其性味咸，平，入肝、肾经，有养血滋阴的功能，治血虚经闭，崩 漏，带下。
具体实施方式[0007] 本发明组分的药物用量也是发明人经过大量摸索总结得出的，各组分的用量在下述重 量范围内都具有较好的疗效： 太子参12-16克，黄芪25-35克，灵芝草12-18克，当归8-12克，川芎8-12克，熟地黄 8-12克，砂仁8-12克，山药15-25克，白芍8-12克，白术10-15克，青蒿10-15克，香附8-12 克，连翘8-12克，枳实8-12克，决明子8-12克，玄参10-15克，瓜蒌6-10克，大黄8-12克， 肉苁蓉8-12克，杏仁5-8克，佛手钳8-12克，柴胡6-10克，厚朴8-12克，山楂25-35克，郁 李仁15-25克，火麻仁25-35克，金银花15-25克，蒲公英15-25克，瓦楞子25-35克，乌贼 鱼肉15-25克。
[0008] 优选为： 太子参15克，黄芪30克，灵芝草15克，当归10克，川考10克，熟地黄10克，砂仁10 克，山药20克，白芍10克，白术12克，青蒿12克，香附10克，连翘10克，枳实10克，决明子 10克，玄参12克，瓜蒌8克，大黄10克，肉苁蓉10克，杏仁6克，佛手钳10克，柴胡8克，厚 朴10克，山楂30克，郁李仁20克，火麻仁30克，金银花20克，蒲公英20克，瓦楞子30克， 乌贼鱼肉20克。
[0009] 本发明药物的制备方法如下 一、备料 1、 太子参：摘除须根，晒干； 2、 黄芪：取黄芪片，加炼熟蜂蜜与开水少许，拌匀，稍闷，置锅内用文火炒至变为黄色， 不粘手为止，取出，放凉 3、 灵芝草：除去杂质，洗净，润软，切厚片，干燥，筛去碎肩； 4、 当归：拣去杂质，洗净，闷润，稍晾，切片晒干； 5、 川芎：拣去杂质，分开大、小个，用水浸泡，晒瞭，闷润后切片，干燥； 6、 熟地黄：取原药材，蒸至表面乌黑色，取出，晒至八成干时，切片，干燥； 7、 砂仁：拣去杂质及果壳，捣碎； 8、 山药：拣去杂质，用水泡至山药中心部软化，捞出稍瞭，切片晒干或烘干； 9、 白芍：取净白芍片，置锅内用文火炒至微黄色，取出，放凉； 10、 白术：先将麸皮撒于热锅内，候烟冒出时，将白术片倒入微炒至淡黄色，取出，筛去 麸皮后放凉，每白术片100斤，用麸皮10斤； 11、 青高：拣去杂质，除去残根，水淋使润，切段，晒干； 12、 香附：拣去杂质，礙成碎粒，鑛去细毛及细末； 13、 连翘：拣净杂质，搓开，除去枝梗； 14、 枳实：拣净杂质，用水浸泡至八成透，捞出，润至内无硬心，切片，晾干； 15、 决明子：取净决明子，置锅内炒至微有香气，取出，放凉； 16、 玄参：拣净杂质，除去芦头，洗净润透，切片，晾干； 17、 瓜蒌：取原药材，除去杂质及果柄，洗净，压扁，切丝或小块，干燥； 18、 大黄：拣净杂质，大小分档，闷润至内外湿度均匀，切片或切成小块、晒干； 19、 肉苁蓉：拣净杂质，清水浸泡，每天换水1-2次，如系咸苁蓉，泡尽盐分，润透，切片 纵向，晒干； 20、 杏仁：拣净杂质，置沸水中略煮，俟皮微皱起捞出，浸凉水中，脱去种皮，晒干，簸 净； 21、 佛手钳：拣去杂质，用水喷润后，切碎，晒干； 22、 柴胡：拣去杂质，除去残茎，洗净泥沙，捞出，润透后及时切片，随即晒干； 23、 厚朴：用水浸泡捞出，润透后刮去粗皮，洗净，切丝，晾干； 24、 山楂：取拣净的山楂，置锅内用武火炒至外面焦褐色，内部黄褐色为止，喷淋清水， 取出，晒干； 25、 郁李仁：筛去泥肩，淘净，拣净杂质和碎壳，晒干，用时捣碎； 26、 火麻仁：拣去杂质及残留外壳，取净仁； 27、 金银花：筛去泥沙，拣净杂质； 28、 蒲公英：拣去杂质，洗净泥土，切段，晒干； 29、 瓦楞子：取瓦楞子放坩锅内，置无烟的炉火中煅至红透，取出放凉，碾碎用； 30、 乌贼鱼肉：肉洗净，鲜用。
[0010] 二、制备 1、 将所述重量的太子参、黄芪、灵芝草、当归、川芎、熟地黄、砂仁、山药、白芍、白术、青 蒿、香附、连翘、枳实、决明子、玄参、瓜蒌、大黄、肉苁蓉、杏仁、佛手钳、柴胡、厚朴、山楂、郁 李仁、火麻仁、金银花、蒲公英、瓦楞子、乌贼鱼肉放入煎药容器内，第一次加水8倍量，浸泡 100分钟后，武火煎煮沸腾，再用文火煎煮20分钟，过滤得第一次煎煮液，将第一次煎煮液 倒入容器内； 2、 将过滤的药渣加水6倍量，武火煮沸，再用文火煎煮20分钟，过滤得第二次煎煮液； 3、 将两次煎煮液混合搅拌均匀，分为3剂服用。
[0011] 组方中肉苁蓉有补肾，益精，润燥，清肠的功能为君药；火麻仁润燥，滑肠，通淋，活 血；当归有补血和血，调经止痛，润燥滑肠的功能，二者为臣药，三味药共同发挥补肾，益精， 补血，活血，润燥，滑肠的作用，治疗便秘效力全面，且以补肾，和血，润燥为主可治本，郁李 仁有润燥，滑肠，下气，利水的功能为佐药，瓜蒌有清热涤痰，宽胸散结，润燥滑肠的功能为 使药，与余下诸药是治标。
[0012] 本发明药物具有补肾益精，补血和血，顺气导滞，清热排毒，润燥滑肠的功能，用于 治疗便秘，疗程短、见效快、治愈后不复发。
[0013]
具体实施方式： 以下通过试验例来进一步阐述本发明所述药物的有益效果，这些试验例包括本发明药 物的动物毒性试验报告和临床疗效观察资料。
[0014][试验例1]本发明药物的动物毒性试验报告： 取家兔30只，雌雄兼用，体重2. 0 - 2. 5kg，分两组，每组15只，其中一组为超剂量试验 组，另一组为正常量试验组。超常量组为20ml/kg，正常量为10ml/kg，给药方式为灌胃法给 药，每天两次，连服7天，每天观察给药反应，结果表明二组家兔活动、饮食正常，药物无不 良毒副作用。
[0015][试验例2]本发明药物的临床疗效观察 1、一般资料 收治便秘门诊患者共30例。
[0016] 2、诊断标准 典型症状为粪便在肠内滞留过久，排便周期延长，或粪质干结，排出困难，或欲大便而 艰涩不畅。患者还常伴有腹胀腹痛、头晕头胀、嗳气食少、心烦失眠、肛裂、出血、痔疮以及气 短乏力，心悸头晕等症状。
[0017] 3、治疗方法 选用上述药剂，给患者服用，每日3次，每次服用1剂，每天早、中、晚各服1次，7天为一 个疗程，连续服用3个疗程。
[0018] 4、疗效评定标准 显效：便秘症状消失，体质恢复正常，痊愈； 好转：患者排便困难，腹胀腹痛现象减轻，便秘症状明显好转，排便周期逐步恢复正 常； 无效：达不到好转标准者。
[0019] 5、治疗结果(见下表）
在上述治疗中，用本发明药物治疗便秘患者30例，结果显效22例，显效率为73. 33%，好 转6例，好转率为20%，无效2例，总有效率为93. 33%。
Claims (3)
1. 一种治疗便秘的药物，其特征在于：它是由下列重量范围内的原料药制成： 太子参12-16克，黄芪25-35克，灵芝草12-18克，当归8-12克，川芎8-12克，熟地黄 8-12克，砂仁8-12克，山药15-25克，白芍8-12克，白术10-15克，青蒿10-15克，香附8-12 克，连翘8-12克，枳实8-12克，决明子8-12克，玄参10-15克，瓜蒌6-10克，大黄8-12克， 肉苁蓉8-12克，杏仁5-8克，佛手钳8-12克，柴胡6-10克，厚朴8-12克，山楂25-35克，郁 李仁15-25克，火麻仁25-35克，金银花15-25克，蒲公英15-25克，瓦楞子25-35克，乌贼 鱼肉15-25克。
2. 根据权利要求1所述的药物，其中各原料药的用量为： 太子参15克，黄芪30克，灵芝草15克，当归10克，川考10克，熟地黄10克，砂仁10 克，山药20克，白芍10克，白术12克，青蒿12克，香附10克，连翘10克，枳实10克，决明子 10克，玄参12克，瓜蒌8克，大黄10克，肉苁蓉10克，杏仁6克，佛手钳10克，柴胡8克，厚 朴10克，山楂30克，郁李仁20克，火麻仁30克，金银花20克，蒲公英20克，瓦楞子30克， 乌贼鱼肉20克。
3. 根据权利要求1或2所述药物的制备方法，它包括下列步骤： (一）备料 (1) 太子参：摘除须根，晒干； (2) 黄芪：取黄芪片，加炼熟蜂蜜与开水少许，拌匀，稍闷，置锅内用文火炒至变为黄色， 不粘手为止，取出，放凉 (3) 灵芝草：除去杂质，洗净，润软，切厚片，干燥，筛去碎肩； (4) 当归：拣去杂质，洗净，闷润，稍晾，切片晒干； (5) 川芎：拣去杂质，分开大、小个，用水浸泡，晒晾，闷润后切片，干燥； (6) 熟地黄：取原药材，蒸至表面乌黑色，取出，晒至八成干时，切片，干燥； (7) 砂仁：拣去杂质及果壳，捣碎； (8) 山药：拣去杂质，用水泡至山药中心部软化，捞出稍晾，切片晒干或烘干； (9) 白芍：取净白芍片，置锅内用文火炒至微黄色，取出，放凉； (10 )白术：先将麸皮撒于热锅内，候烟冒出时，将白术片倒入微炒至淡黄色，取出，筛去 麸皮后放凉，每白术片100斤，用麸皮10斤； (11) 青蒿：拣去杂质，除去残根，水淋使润，切段，晒干； (12) 香附：拣去杂质，礙成碎粒，鑛去细毛及细末； (13) 连翘：拣净杂质，搓开，除去枝梗； (14) 枳实：拣净杂质，用水浸泡至八成透，捞出，润至内无硬心，切片，晾干； (15) 决明子：取净决明子，置锅内炒至微有香气，取出，放凉； (16) 玄参：拣净杂质，除去芦头，洗净润透，切片，晾干； (17) 瓜蒌：取原药材，除去杂质及果柄，洗净，压扁，切丝或小块，干燥； (18) 大黄：拣净杂质，大小分档，闷润至内外湿度均匀，切片或切成小块、晒干； (19) 肉苁蓉：拣净杂质，清水浸泡，每天换水1-2次，如系咸苁蓉，泡尽盐分，润透，纵向 切片，晒干； (20) 杏仁：拣净杂质，置沸水中略煮，俟皮微皱起捞出，浸凉水中，脱去种皮，晒干，簸 净； (21) 佛手钳：拣去杂质，用水喷润后，切碎，晒干； (22) 柴胡：拣去杂质，除去残茎，洗净泥沙，捞出，润透后及时切片，随即晒干； (23) 厚朴：用水浸泡捞出，润透后刮去粗皮，洗净，切丝，晾干； (24) 山楂：取拣净的山楂，置锅内用武火炒至外面焦褐色，内部黄褐色为止，喷淋清水， 取出，晒干； (25) 郁李仁：筛去泥肩，淘净，拣净杂质和碎壳，晒干，用时捣碎； (26) 火麻仁：拣去杂质及残留外壳，取净仁； (27) 金银花：筛去泥沙，拣净杂质； (28) 蒲公英：拣去杂质，洗净泥土，切段，晒干； (29) 瓦楞子：取瓦楞子放坩锅内，置无烟的炉火中煅至红透，取出放凉，碾碎用； (30) 乌贼鱼肉：肉洗净，鲜用； (二）制备 (1) 将所述重量的太子参、黄芪、灵芝草、当归、川芎、熟地黄、砂仁、山药、白芍、白术、青 蒿、香附、连翘、枳实、决明子、玄参、瓜蒌、大黄、肉苁蓉、杏仁、佛手钳、柴胡、厚朴、山楂、郁 李仁、火麻仁、金银花、蒲公英、瓦楞子、乌贼鱼肉放入煎药容器内，加水8倍量，浸泡100分 钟后，武火煎煮沸腾，再用文火煎煮20分钟，过滤得第一次煎煮液，将第一次煎煮液倒入容 器内； (2) 将过滤的药渣加水6倍量，武火煮沸，再用文火煎煮20分钟，过滤得第二次煎煮 液； (3) 将两次煎煮液混合搅拌均匀，分为3剂服用。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510748617.6A CN105213946A (zh) | 2015-11-07 | 2015-11-07 | 一种治疗便秘的药物及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510748617.6A CN105213946A (zh) | 2015-11-07 | 2015-11-07 | 一种治疗便秘的药物及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105213946A true CN105213946A (zh) | 2016-01-06 |
Family
ID=54983458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510748617.6A Pending CN105213946A (zh) | 2015-11-07 | 2015-11-07 | 一种治疗便秘的药物及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105213946A (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108635457A (zh) * | 2018-07-26 | 2018-10-12 | 王小岗 | 一种治疗便秘的中药组合物及其制备方法与应用 |
-
2015
- 2015-11-07 CN CN201510748617.6A patent/CN105213946A/zh active Pending
Non-Patent Citations (3)
| Title |
|---|
| 宋丙跃: ""中药内服配合保留灌肠治疗慢性传输型便秘疗效观察"", 《中国中医急症》 * |
| 杨永勤: ""中医药治疗高原地区习惯性便秘78例"", 《西南军医》 * |
| 谷元铸等: ""益气养血汤治疗老处性便秘的体会"", 《工企医刊》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108635457A (zh) * | 2018-07-26 | 2018-10-12 | 王小岗 | 一种治疗便秘的中药组合物及其制备方法与应用 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103610978B (zh) | 一种治疗失眠的药物及其制备方法 | |
| CN103479896B (zh) | 一种治疗脑血栓的药物及其制备方法 | |
| CN105477614A (zh) | 一种治疗肥胖的药物及其制备方法 | |
| CN103751682B (zh) | 一种治疗肺热咳嗽的药物及其制备方法 | |
| CN105148106A (zh) | 一种治疗肺痨的药物及其制备方法 | |
| CN103656406B (zh) | 一种治疗肺结核的药物及其制备方法 | |
| CN103977306A (zh) | 一种治疗乙型肝炎的药物及其制备方法 | |
| CN105362889A (zh) | 一种治疗耳鸣的药物及其制备方法 | |
| CN104352758A (zh) | 一种治疗高血压的药物及其制备方法 | |
| CN103961616A (zh) | 一种治疗过敏性咳嗽的药物及其制备方法 | |
| CN104056223A (zh) | 一种治疗疣的药物及其制备方法 | |
| CN106110184A (zh) | 一种治疗脂肪肝的药物及其制备方法 | |
| CN105343490A (zh) | 一种治疗痔疮的药物及其制备方法 | |
| CN103536839B (zh) | 一种治疗膀胱炎的药物及其制备方法 | |
| CN103263555B (zh) | 一种治疗功能失调性子宫出血的药物及其制备方法 | |
| CN105457001A (zh) | 一种治疗小儿多动症的药物及其制备方法 | |
| CN103263575B (zh) | 一种治疗头痛的药物及其制备方法 | |
| CN104352709A (zh) | 一种治疗胃溃疡的药物及其制备方法 | |
| CN105213946A (zh) | 一种治疗便秘的药物及其制备方法 | |
| CN104398925A (zh) | 一种治疗皮肤病的药物及其制备方法 | |
| CN103735833B (zh) | 一种治疗小儿脱发的药物及其制备方法 | |
| CN106177857A (zh) | 一种治疗习惯性流产的药物及其制备方法 | |
| CN105326996A (zh) | 一种治疗痔疮的药物及其制备方法 | |
| CN105456928A (zh) | 一种治疗类风湿性关节炎的药物及其制备方法 | |
| CN105327194A (zh) | 一种治疗贫血的药物及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160106 |