CN105198813B - 3‑甲基‑1h‑吲唑的合成工艺 - Google Patents
3‑甲基‑1h‑吲唑的合成工艺 Download PDFInfo
- Publication number
- CN105198813B CN105198813B CN201510613050.1A CN201510613050A CN105198813B CN 105198813 B CN105198813 B CN 105198813B CN 201510613050 A CN201510613050 A CN 201510613050A CN 105198813 B CN105198813 B CN 105198813B
- Authority
- CN
- China
- Prior art keywords
- indazoles
- acetophenones
- synthesis
- nitro
- aminoacetophenones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510613050.1A CN105198813B (zh) | 2015-09-23 | 2015-09-23 | 3‑甲基‑1h‑吲唑的合成工艺 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510613050.1A CN105198813B (zh) | 2015-09-23 | 2015-09-23 | 3‑甲基‑1h‑吲唑的合成工艺 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105198813A CN105198813A (zh) | 2015-12-30 |
CN105198813B true CN105198813B (zh) | 2018-04-03 |
Family
ID=54946811
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510613050.1A Active CN105198813B (zh) | 2015-09-23 | 2015-09-23 | 3‑甲基‑1h‑吲唑的合成工艺 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105198813B (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108558756B (zh) * | 2018-05-25 | 2021-08-03 | 沈阳药科大学 | 2-芳基-2,3-二氢-4(1h)-喹啉酮缩氨基脲类化合物及其应用 |
CN110128347A (zh) * | 2019-06-17 | 2019-08-16 | 韶远科技(上海)有限公司 | 一种1-甲基-1h-吲唑-6-甲酸的合成方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101985424A (zh) * | 2010-09-21 | 2011-03-16 | 浙江工业大学 | 一种合成邻硝基苯乙酮类化合物的方法 |
CN102898374A (zh) * | 2012-11-05 | 2013-01-30 | 上海毕得医药科技有限公司 | 一种1h-吲唑类衍生物的制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8022227B2 (en) * | 2008-08-27 | 2011-09-20 | The Ohio State University | Method of synthesizing 1H-indazole compounds |
-
2015
- 2015-09-23 CN CN201510613050.1A patent/CN105198813B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101985424A (zh) * | 2010-09-21 | 2011-03-16 | 浙江工业大学 | 一种合成邻硝基苯乙酮类化合物的方法 |
CN102898374A (zh) * | 2012-11-05 | 2013-01-30 | 上海毕得医药科技有限公司 | 一种1h-吲唑类衍生物的制备方法 |
Non-Patent Citations (2)
Title |
---|
A Practical, Metal-Free Synthesis of 1H-Indazoles;Carla M. Counceller,等;《Org. Lett.》;20080130;第10卷(第5期);第1021-1023页 * |
Efficient and Selective Reduction of Aromatic Notro Compounds to Aromatic Amine by NbCl5/Indium System;Byung Woo Yoo,等;《Bulletin of the Korean chemical society》;20121231;第33卷(第9期);第2851-2852页 * |
Also Published As
Publication number | Publication date |
---|---|
CN105198813A (zh) | 2015-12-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105198813B (zh) | 3‑甲基‑1h‑吲唑的合成工艺 | |
TWI703163B (zh) | 舒更葡糖鈉之製備方法及其晶型 | |
CN105198863A (zh) | 一种制备高纯度氯沙坦的方法 | |
CN107056756A (zh) | 一种制备高纯度氯沙坦的方法 | |
CN109810031B (zh) | 非罗考昔中间体的制备方法 | |
CN102241722A (zh) | 一种合成孕酮受体调节剂优力司特的纯化方法 | |
CN101270124B (zh) | 一种提纯制备高纯度荧光素及荧光素盐的新方法 | |
CN108358900A (zh) | 一种阿法替尼及其马来酸盐的制备方法 | |
CN108047138A (zh) | 无肼l-肌肽的制备方法 | |
CN104326954B (zh) | 一种福多司坦的合成方法 | |
CN107383418B (zh) | 一种抗紫外线塑料添加剂及其制备方法 | |
CN108329276A (zh) | 杂环衍生物及其制备和用途 | |
CN106674205A (zh) | 一种沙坦类化合物脱色的方法 | |
CN104447715B (zh) | 奥美沙坦酯的制备方法 | |
CN105399790A (zh) | 一种3-酮-4-雄烯-17β羧酸的合成方法 | |
CN106565776A (zh) | 一种4‑(甲基羟基磷酰基)‑2‑羰基丁酸的分离提纯方法 | |
CN108203455B (zh) | 一种双氢非那雄胺碘化物脱碘制备非那雄胺的方法 | |
US20220235010A1 (en) | Synthesis method for 1-methyl-1h-indazole-6-carboxylic acid | |
CN104926682A (zh) | 一种对氯苯肼盐酸盐的制备方法 | |
CN106866378B (zh) | 一种间苯三酚的合成工艺 | |
CN103922959A (zh) | 一种有机合成中间体乙酰氨基丙二酸二乙酯的制备方法 | |
CN101659624A (zh) | N-烷基天门冬氨酸碱土金属盐的制备方法 | |
CN108752230A (zh) | 一种造影剂碘克沙醇杂质e的关键中间体的合成方法 | |
CN108586460A (zh) | 一种恩替卡韦中间体的制备方法 | |
KR101088892B1 (ko) | 4-시아노 벤질브로마이드의 제조방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Synthesis of 3-methyl-1h-indazole Effective date of registration: 20220615 Granted publication date: 20180403 Pledgee: The Bank of Shanghai branch Caohejing Limited by Share Ltd. Pledgor: SHANGHAI TITAN TECHNOLOGY Co.,Ltd. Registration number: Y2022310000059 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20230802 Granted publication date: 20180403 Pledgee: The Bank of Shanghai branch Caohejing Limited by Share Ltd. Pledgor: SHANGHAI TITAN TECHNOLOGY Co.,Ltd. Registration number: Y2022310000059 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Synthesis process of 3-methyl-1H-indole Effective date of registration: 20230829 Granted publication date: 20180403 Pledgee: The Bank of Shanghai branch Caohejing Limited by Share Ltd. Pledgor: SHANGHAI TITAN TECHNOLOGY Co.,Ltd. Registration number: Y2023310000500 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |