CN104800660A - Traditional Chinese medicine preparation for treating mycoplasma pneumoniae pneumonia and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating mycoplasma pneumoniae pneumonia. The traditional Chinese medicine preparation comprises the following components in proportion by weight: honeysuckle, fructus forsythiae, dyer woad leaf, indigowoad root, reed rhizome, mulberry leaf, lalang grass rhizome, root of kudzu vine, cyrtomium rhizome, tatarian aster root, pepperweed seed, orange fibers, common coltsfoot flower, thunberg fritillary bulb, fried bitter apricot kernel, gypsum, common hogfennel root, heartleaf houttuynia herb, whiteflower patrinia herb, platycodon root, angelica root, wild chrysanthemum and raw licorice root. The traditional Chinese medicine preparation has the advantages that the effects of clearing heat and detoxifying, expelling wind and relieving heat, clearing lungs and moistening dryness, and relieving exterior syndromes and abating heat are realized; the mycoplasma pneumoniae pneumonia can be effectively treated.

Description

A kind of Chinese medicine preparation for the treatment of mycoplasma pneumoniae pneumonia and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for the treatment of mycoplasma pneumoniae pneumonia.The invention still further relates to the preparation method of this Chinese medicine preparation.

Background technology

Mycoplasma pneumoniae pneumonia is the pneumonia caused by mycoplasma pneumoniae, once claims primary atypical pneumonia.Onset is slow, has heating, paroxysmal irritable cough, a small amount of mucus or mucus purulent sputum (occasionally having bloody sputum).How not obvious physical signs of lung is, but easily cause the outer multisystem of lung to get involved, also can life-threatening or death.Be apt to occur in child or teenager, account for 15% ~ 30% of pneumonia sum, popular year can up to 40% ~ 60%; General prognosis bona is self-limited disease.Mycoplasma pneumoniae pneumonia is the respiratory tract infection caused by mycoplasma pneumoniae, has pharyngitis, bronchitis and pneumonia.Mycoplasma pneumoniae is one of minimum microorganism that can grow on cell-free medium, average diameter 125 ~ 150um, acellular wall, can grow on the agar culture medium containing serum albumin and sterol, after 2 ~ 3 weeks, bacterium colony is fried egg shape, central thicker, low flat around.The secretions of mycoplasma per os, nose is propagated in atmosphere, causes the respiratory tract infection of distributing or little popular.

Mycoplasma pneumoniae pneumonia shows as cough for the outstanding symptom of primary disease, generally in 2 ~ 3 days after being ill, is just dry cough, after transfer intractable play to and cough, often have sticky sputum idol to be with the blood streak, minority case can the apasm of coughing of similar pertussis sample.Sustainable 1 ~ 4 week.How not obvious physical signs of lung is, even completely without.Minority can hear dry, moist rales pleasure.But polylith disappears, therefore sign and play are coughed and the clinical manifestation such as heating is inconsistent, are one of primary disease feature.Infant onset is anxious, and the course of disease is long, and the state of an illness is heavier, show as dyspnea, breathe heavily suppress, sound of stridulating is comparatively outstanding, pulmonary's rale is more than Annual wool yield.Part infant child can suffer from hemolytic anemia, meningitis, myocarditis, groan, Green-Pulmonary hypofuntion such as sharp syndromes.

The treatment of mycoplasma pneumoniae pneumonia can use suitable antibacterials can mitigation symptoms and shorten the course of disease in early days, general multiplex Macrolide antibacterials, but use western medicine mycoplasma pneumoniae pneumonia not only treatment time long, and side effect is strong, affect the growth of child, life-time service antibiotic also can produce drug resistance, causes irreversible damage to the health of patient.Motherland's traditional Chinese medical science employing safety, the Chinese medicine that toxic and side effects is little carry out treating both the principal and secondary aspects of a disease, thus effectively can treat mycoplasma pneumoniae pneumonia.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine preparation, this Chinese medicine preparation has evident in efficacy for treatment mycoplasma pneumoniae pneumonia, cheap, has no side effect, not easily recurs, the feature of safe ready.

Another object of the present invention is to provide the preparation method of the Chinese medicine preparation of this treatment mycoplasma pneumoniae pneumonia.

Inventor is in clinical treatment practice for many years, observe the misery that mycoplasma pneumoniae pneumonia brings to patient, according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out a kind of new formula for the treatment of the Chinese medicine preparation of mycoplasma pneumoniae pneumonia repeatedly, the present invention selects Flos Lonicerae, Fructus Forsythiae, Folium Isatidis, Radix Isatidis, Rhizoma Phragmitis, Folium Mori, Rhizoma Imperatae, Radix Puerariae, Rhizoma Osmundae, Radix Asteris, Semen Lepidii (Semen Descurainiae), Vascular aurantii, Flos Farfarae, Bulbus Fritillariae Thunbergii, Semen Armeniacae Amarum (parched), Gypsum Fibrosum, Radix Peucedani, Herba Houttuyniae, Herba Patriniae, Radix Platycodonis, the Radix Angelicae Dahuricae, Flos Chrysanthemi Indici, Radix Glycyrrhizae combines, each efficacy of drugs is made by these drug regimens to produce synergism, make it that there is heat-clearing and toxic substances removing, wind-dispelling heat-dissipating, clearing away lung-heat and moistening for dryness, to induce sweat the effect of bringing down a fever, thus effectively can treat mycoplasma pneumoniae pneumonia.

The effect of Chinese medicine of the present invention:

Wherein:

Flos Lonicerae: the flower that dry flower or band for caprifoliaceae plant Radix Ophiopogonis Lonicera japonica Thunb., Flos Lonicerae Lonicera hypoglauca Miq., Flos Lonicerae (hair calyx Radix Ophiopogonis) Lonicera confusa DC. or hair style Radix Ophiopogonis Lonicera dasystyla Rehd. are just opened.Nature and flavor: sweet, cold.Return lung, the heart, stomach warp.Effect: heat-clearing and toxic substances removing, wind-dispelling heat-dissipating.This product is sweet in flavor and cold in property, can heat-clearing and toxic substances removing, again kind loose carbuncle detumescence, for treating the key medicine of all YANG syndrome carbuncle furuncle.Clinically for carbuncle furunculosis: be often equal to use with Herba Violae, Flos Chrysanthemi Indici, can antipyretic and antidote functions be strengthened, can in order to carbuncle furunculosis, congestion and swelling pain.

Fructus Forsythiae: be the dry fruit of Oleaceae plants Fructus Forsythiae Forsythia suspensa (Thunb.) Vahl.Nature and flavor: bitter, are slightly cold.Return lung, the heart, small intestine meridian.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.Fructus Forsythiae is normal with the same use of Flos Lonicerae, Fructus Forsythiae bitter in the mouth cool in nature, gently clearly to float, and can control all heat of the part of the body cavity above the diaphragm housing the heart and lungs, outstanding energy removing toxicity for eliminating carbuncles and eliminating stagnation, therefore is the key medicine of persons particularly liable to develop skin infection.Fructus Forsythiae has broad-spectrum antibacterial action, has very strong inhibitory action to staphylococcus aureus, Hayes dysentery bacterium, has certain inhibitory action to other pathogenic bacterium, influenza virus, fungus.There is antiinflammatory action.Antibacterial action: Fructus Forsythiae concentrated decotion has antibacterial action in vitro, can suppress Bacillus typhi, Salmonella paratyphi, escherichia coli, dysentery bacterium, diphtheria corynebacterium and vibrio cholera, staphylococcus, streptococcus etc.Fructus Forsythiae antimicrobial spectrum is very wide, has obvious antiinflammatory action, can promote the formation of inflammatory barrier, reduces capillary permeability, reduces inflammatory exudation.

Folium Isatidis: be the dried leaves of cruciferae isatis Isatis indigotica Fort..Nature and flavor: bitter, cold.Return liver, the heart, stomach warp.Effect: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Be mainly used in pyretic toxicity and send out the diseases such as speckle, erysipelas, laryngopharynx swelling and pain, aphtha of the mouth and tongue, sore and toxic.The extensive use clinically of this medicine, control except above-mentioned all diseases except available, can be used for again expectorant heat stagnation lung, cough up phlegm yellow thick; Especially be usually used in popular second encephalitis, both can be applied to prevention by single, and Radix Bupleuri, Flos Lonicerae, Radix Isatidis, Radix Scrophulariae, the Radix Rehmanniae etc. can be coordinated again, the pyretic toxicity that energy removing summer-heat edema caused by disorder of QI, battalion divide, and comparatively suitable with partial heat type.This product bitter cold, the stomach two that can clear away heart-fire is through excess-fire, and kind solution pestilence seasonal noxious pathogen, has the effect of resolving toxin and disinhibiting the throat again.This product bitter cold, be removing toxic substances key medicine, have stronger antivirus action, modern with controlling upper respiratory tract infection, influenza, encephalitis, viral pneumonia, hepatitis, enteritis etc. have good curative effect.

Radix Isatidis: be the dry root of cruciferae isatis Isatis indigotica Fort..Nature and flavor: bitter, cold.Return liver, stomach warp.Effect: heat clearing away, removing toxic substances, removing heat from blood, sore-throat relieving.Radix Isatidis and Folium Isatidis belong to the different medicinal effects of same plant, have similar effect, but Radix Isatidis is more good at resolving toxin and disinhibiting the throat eliminating stagnation, is mainly used in maculae caused by violent heat pathogen; High heat headache; Major part pestilence; Crimson tongue is purple dark, scarlet fever; Erysipelas; Mumps; Sore throat; Skin ulcer is swollen, carbuncle; Chickenpox; Measles; Hepatitis etc.

Rhizoma Phragmitis: be the fresh or dry rhizome of grass phragmites communis Phragmites communis Trin..Nature and flavor: sweet, cold.Return lung meridian, stomach warp.Function: clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.Cure mainly: for calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.Rhizoma Phragmitis one medicine, is mainly used in following two aspects clinically, can clearing away lung-heat and evacuation of pus of eliminating the phlegm, again can clearing away stomach-heat and the preventing or arresting vomiting that promotes the production of body fluid.Though its attribute is trembled with fear, slightly sweet flavor and power use lung heat clearing stomach, can only as auxiliary medicine.But, it has an advantage, and namely property is not grown greasy, promotes the production of body fluid and does not love heresy, and all epidemic febrile disease deep loves are defended, gas, or if any the syndrome that impairment of body fluid is thirsty after calentura, all can apply.

Folium Mori: be the dried leaves of moraceae plants Mulberry Morus alba L..Nature and flavor: sweet, bitter, cold.Return lung, Liver Channel.Effect: dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.Folium Mori are gently dispersed clearly, wind heat of faling apart, but effect is more weak.Clinical being mainly used in lets out clearly lung liver, as wind heat attacks lung, cough ant phlegm, or dryness-heat impairing the lung, dry cough without phlegm; And wind heat is attacked or the disease such as flaming up of liver-fire, conjunctival congestion and swelling pain, be conventional medicine.

Rhizoma Imperatae: be the rhizome of grass perennial herb Herba Imperatae Imperata cylindrica.Nature and flavor: sweet, cold.Return lung, stomach, urinary bladder channel.Effect: cooling blood for hemostasis, clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria; Acute nephritis edema." Bencao Jingshu " is recorded: impairment caused by overstrain void is won, must interior-heat, and Rhizoma Imperatae is sweet can spleen reinforcing, sweet, though cold and do not violate stomach.Gan Hanneng is except interior-heat, therefore main impairment caused by overstrain void is won.Strengthening the spleen so invigorating middle warmer, heat extraction so QI invigorating, the beneficial blood of sweet energy, heat in blood is the stasis of blood then, and the stasis of blood is then closed, and closes then cold and heat and does, cold and cool blood, sweet beneficial blood, heat go then blood and, and then stagnation resolvation and close logical, general rule cold and heat are from only also.Dysuria, due to interior-heat also, pyrolysis then just diarrhea.Pouring person, caused by blood system deficiency-heat also, removing heat from blood benefit blood, then drench spontaneous recovery, and the exopathogenic heat of the intestines and stomach is explained by oneself, and body fluid is raw and yearningly also stop.Blood stored in the liver and main muscle, cool liver of enriching blood, then muscle is hard.Heat in blood then collapses, and removing heat from blood and blood, then collapse spontaneous recovery.Heat in blood is absurd row then, overflow upper orifices for telling, for coughing up, be epistaxis, bleeding from the gum, removing heat from blood and blood, then all cards are from removing.Strengthening the spleen invigorating middle warmer, diuresis, therefore swollen jaundice of also harnessing the river, and hold concurrently reason typhoid fever hiccup also.

Radix Puerariae: be the dry root of legume pueraria lobata Pueraria lobata (Willd.) Ohwi.Nature and flavor: cool, sweet, pungent.Enter spleen, stomach warp.Effect: induce sweat and bring down a fever, promotes the production of body fluid, rash, yang invigorating antidiarrheal.Radix Puerariae is sweet pungent cool in nature, and lightly floating, it is loose to rise, and enters taste warp, has relieving the exterior syndrome by diaphoresis, the merit of expelling pathogenic factors from muscles for reducing heat.

Rhizoma Osmundae: be Dryopteridaceae plant dryopteris crassirhizoma, Athyriaceae plant lunathyrium acrostichoidesChing, ball Pteridiaceae plant Matteuccia strthiopteris, Osmundaceae plant osmund, the rhizome of Blechnaceae plant Blechnum orientale Linn., Brainea insignis, Rhizoma Osmundae etc.Nature and flavor: bitter; Puckery; Be slightly cold; Slightly poisonous, return liver; Stomach warp, effect: parasite killing; Heat clearing away; Removing toxic substances; Cooling blood for hemostasis.Main anemopyretic cold; Warm skin eruption; Spit blood; Hemoptysis; Epistaxis; Have blood in stool; Metrorrhagia; Dysentery; The intestinal parasitic diseases such as leukorrhagia and hook, ascarid, cestode.

Radix Asteris: be the dry root and rhizome of feverfew Radix Asteris Aster tataricus L. f..Nature and flavor: pungent, bitter, temperature.Return lung meridian.Effect: nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm.Breath with cough for abundant expectoration, new chronic cough is coughed, chronic cough hemoptysis.The traditional Chinese medical science thinks that Radix Asteris has warming the lung, the therapeutic method to keep the adverse QI flowing downwards, the function that expectorant, cough-relieving are coughed.Experiment shows, water decoction has phlegm-dispelling functions and without antitussive and antiasthmatic effect; Benzene and methanolic extract also have phlegm-dispelling functions.Radix Asteris has certain inhibitory action to 7 kinds of Gram-negative enteral pathogenic bacterium such as escherichia coli, dysentery bacterium, mycetozoan, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus and vibrio cholera in vitro; And have the effect of antagonism pathogenic fungus.Water decoction infected by influenza in chick embryo allantois has obvious inhibitory action.There is significantly antibacterial and antiviral effect.This product master enters lung meridian, and bitter in the mouth falls to be let out, slightly warm in nature and matter profit, has again the property of unclogging and readjusting and opening concurrently, can fall lung qi, again can lung qi dispersing gas and reach the merit of relieving cough and asthma, is the key medicine for the treatment of cough with asthma.

Semen Lepidii (Semen Descurainiae): be the dry mature seed of crucifer Lepidium sativum L. Lepidium apetalum Willd. or descurainia sophia (l.) webb ex prantl Descurainia sophia (L.) Webb ex prantl.Nature and flavor: pungent, bitter, Great Cold.Return lung, urinary bladder channel.Effect: eliminating pathogen from the lung for relieving asthma, line water detumescence.Stop up lung for sputum, dyspnea and cough with excessive sputum, fullness and distention in the chest and hypochondrium, must not put down sleeping, and ascites pleural fluid swells, dysuria; Pulmonary heart disease edema." Bencao Jingshu ": " Semen Lepidii is the positive medicine of meridian of Hand-TAI YIN, therefore Zhong Jing eliminating the pathogens from the lung soup with it, also start with sun bright, meridian of Foot-TAI YANG.The lung belonging to metal, main fur, bladder belongs to water, hides body fluid, and then bladder is with here for obstruction of lung-QI, and it is obstructed that the upper orifices of example closes then lower orifices, and lower orifices are obstructed, then water is wet overflows for dyspnea with fullness of the chest, for swelling, for gathering, all diease occurrences.Pungent energy falls apart, and hardship can be let out, and Great Cold is heavy cloudy can descendingly relieve oedema or abdominal distension through diuresis or purgation, thus can treat " herbal classic " lead all diseases.

Vascular aurantii: be the grain in the peel of rutaceae orange Citrus reticulata Blanco.Nature and flavor: bitter are flat.Return liver, spleen two warp.Effect: dredging collateral; Regulate the flow of vital energy; Reduce phlegm.Main blockage of meridian-QI; Chronic cough chest pain; Sputum mixed with blood; Get sick from drinking too much wine thirsty.

Flos Farfarae: be the dry flower of feverfew coltsfoot Tussilago farfara L..Nature and flavor: pungent, micro-hardship, temperature.Return lung meridian.Effect: nourishing the lung to keep the adverse QI downward, relieving cough and resolving phlegm.Cough for new chronic cough, dyspnea and cough with excessive sputum, chronic cough hemoptysis.Be mainly used in asthma and chronic tracheitis clinically." property of medicine opinion ": the main treatment lung qi heart is urged, anxious hot weary labor, cough repeatedly without cease, tears saliva is sticky.Control consumptive lung disease lung abscess vomiting pus.

Bulbus Fritillariae Thunbergii: be the dry bulb of liliaceous plant Bulbus Fritillariae Thunbergii Fritillaria thunbergii Miq..Nature and flavor: bitter, cold.Return lung, heart channel.Effect: heat clearing away eliminating stagnation, preventing phlegm from forming and stopping coughing.For wind-heat invading the lung, phlegm-fire cough, lung abscess, acute mastitis, scrofula, sore." book on Chinese herbal medicine is just " is recorded: control greatly lung abscess lung and wither, cough with asthma, and spit blood, mental disorder, falls most in epistaxis, kind relieving stagnation, and relieve the pain pain, and relieving distension is full, clearing away liver-fire, improve visual and auditory acuity, except seasonal epidemic pathogens dysphoria with smothery sensation, and jaundice stranguria with urinary obstruction, hematuria of having blood in stool; Relieving heat toxin, kill parasites and treat sore throat, scrofula, acute mastitis carbuncle on the back, all carbuncle and ulcer toxic swellings, damp and hot malignant boil, anal fistula, incised wound is hemorrhage, burn pain, and than Bulbus Fritillariae Cirrhosae, the merit of falling clearly, not less than several times.

Semen Armeniacae Amarum (parched): be the dry mature seed of rosaceous plant Prunus armeniaca L.var.ansu Maxim. (bitter Fructus Pruni) Prunus armeniaca L. var. ansu Maxim., Siberia Fructus Pruni (Prunus armeniaca L.var.ansu Maxim.) Prunus sibirica L., prunus mandshuricaKoehne Prunus mandshurica (Maxim.) Koehne or Fructus Pruni Prunus armeniaca L..Nature and flavor: bitter, tepor; Slightly poisonous.Return lung, large intestine channel.Effect: sending down the abnormal ascending QI relieving cough and asthma, loosening bowel to relieve constipation.For cough and asthma, fullness in the chest abundant expectoration, blood deficiency Tianjin is withered, dryness of the intestine constipation.

Gypsum Fibrosum: be Sulfates mineral anhydrite race Gypsum Fibrosum, main containing hydrous calcium sulfate (CaSO42H2O).Nature and flavor: sweet, pungent, Great Cold.Attach to the lung and stomach meridians.Effect: clearing away heat-fire, relieving restlessness is quenched the thirst.For fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, headache, toothache.For cough due to lung-heat, asthma.Pathogenic heat attack lung, the diseases such as body Fa Gaore, cough, flaring of nares out of breath, thirst with desire to drink, available Gypsum Fibrosum eliminating heat from the lung.

Radix Peucedani: be the dry root of samphire Peucedanum praeruptorum DUNN Peucedanum praeruptorum Dunn or RADIX PEUCEDANI Peucedanum decursivum Maxim..Nature and flavor: bitter, pungent, are slightly cold.Return lung meridian.Effect: loose wind heat clearing away, lowering the adverse-rising QI to resolve phlegm.For cough due to pathogenic wind-heat's abundant expectoration, expectorant dyspnea of heat type is full, coughs up phlegm yellow thick.This product hardship can be fallen and be let out, the heat clearing away of cold energy, for accumulation of phlegm-heat in the lung, and impairment of dispersing and descending function of the lung.Radix Peucedani can also dispersing wind-cold, and dispersing lung-QI and dissipating phlegm, for cough with copious phlegm person.

Herba Houttuyniae: be the drying water upper part of Saururaceae herbaceos perennial Herba Houttuyniae Houttuynia cordata Thunb..Property: be slightly cold, bitter in the mouth.Return lung meridian, bladder, large intestine channel.Effect: heat-clearing and toxic substances removing; Removing pus and relieving carbuncle; Inducing diuresis for treating stranguria syndrome.Raise a kind of yellow oil in Herba Houttuyniae, all have inhibitory action to various microorganism (especially yeast and mycete), have obvious inhibitory action to the streptococcus of hemolytic, staphylococcus aureus, hemophilus influenza, micrococcus catarrhalis, streptococcus pneumoniae.Also effect is had to escherichia coli, dysentery bacterium, Bacillus typhi.In vitro tests proves, Herba Houttuyniae decoct all has inhibitory action in various degree to multiple gram-positive bacteria and negative bacteria such as staphylococcus aureus, Staphylococcus albus, Hemolytic streptococcus, Diplococcus pneumoniae, micrococcus catarrhalis, diphtheria corynebacterium, Bacillus proteus, will he, Amur, Fu Shi and bacterium sonnei, bacillus enteritidis etc.

Herba Patriniae: be Herba Patriniae section plant Hemerocallis citrina Baroni dragon bud Patrinia scabiosaefolia Fisch. ex Link., patrima villosa (bitter vegetarian) P. villosa (Thunb.) Juss., with root stock and root, all herbal medicine.Nature and flavor: pungent, bitter, cool.Return stomach, large intestine, Liver Channel.Effect: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood circulation promoting competent silt.For acute appendicitis, lung abscess and sore and toxic, the stagnant caused breast abdomen pain of the excess-heat stasis of blood, the diseases such as the stagnant stomachache of the stasis of blood in puerperal.

Radix Platycodonis: be the root of dicotyledon campanulaceae Campanulaceae Radix Platycodonis Platycodon grandiflorum (Jacq.) A. DC..Nature and flavor are bitter, pungent, tepor.Enter lung meridian.Effect: lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus, sharp the five internal organs, fill blood, mend five kinds of over strain, foster the spirit of nobility.Radix Platycodonis is lung meridian edema caused by disorder of QI medicine, and pains are put down, and namely rises and falls, being good at a surname and opening lung qi, therefore exopathogen violates lung, cough with copious phlegm, and disease such as grade uncomfortable in chest of having a stuffy nose, no matter cold and heat all can adapted.

The Radix Angelicae Dahuricae: be the dry root of samphire Radix Angelicae Dahuricae Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. or Radix angelicae dahuricae Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. var.formosana (Boiss.) Shan et Yuan.Nature and flavor: pungent, warm.Attach to the lung and stomach meridians.Effect: expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping.For headache, toothache, nasal sinusitis, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus.Belong to wind and cold person compatibility Herba Schizonepetae, Radix Saposhnikoviae, pus goes out freely not join Flos Lonicerae, Radix Trichosanthis with using.With controlling skin infection, the person that do not burst can impel dissipation, and the person that burst can promote evacuation of pus, therefore is surgery common medicine.Water decoction to escherichia coli, adopt Shigella flexneri, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus, Bacillus proteus, vibrio cholera, human body tubercule bacillus etc. and have inhibitory action." book on Chinese herbal medicine is looked for the truth ": the Radix Angelicae Dahuricae, temperature power is thick, sensible row table, is Foot yangming Channel expelling pathogenic wind and eliminating dampness principal agent.Therefore all diseases of energy all women's head-ornaments of Zhi Yangming, as head's dusk pain, supraorbital bone pain, and gingiva osteodynia, dark complexion scar defect person is also.And its wind heat takes advantage of lung, on sparkle in brain, ooze for deep tears; Move in large intestine, become metrorrhagia blood and close, hemorrhoidal hamorrhage hemorrhoid complicated by anal fistula carbuncle; Wind and damp and hot, sends out in skin, becomes skin infection pruritus due to dryness; All loose solution of temperature can hold in the palm, and the wind of space between skin and muscles is known, stay the carbuncle of knot to dive and disappear, reach on really dispeling the wind, wet dissipation fire wants agent also.

Flos Chrysanthemi Indici: be the dry capitulum of feverfew Herba Dendranthematis indici Chrysanthemum indicum L..Nature and flavor: bitter, pungent, are slightly cold.Return liver, heart channel.Effect: heat-clearing and toxic substances removing.For furuncle carbuncle, conjunctival congestion and swelling pain, has a headache dizzy.The merit of Flos Chrysanthemi heat-clearing and toxic substances removing is excellent, is surgery key medicine, is mainly used in the disease of pathopyretic ulcer, red and swollen heat pain, especially has good efficacy, both oral administrations especially, can mash external application again for the furuncle poison that swells and ache.The product fit applications of the normal and heat-clearing and toxic substances removing such as Herba Violae, Herba Taraxaci clinically.

Radix Glycyrrhizae: be the dry root and rhizome of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza Inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza Glabra L..Nature and flavor: sweet are flat.GUIXIN, lung, spleen, stomach warp.Effect: spleen reinforcing stomach function regulating, Yiqi and vein recovery." Japan hanako materia medica ": peace soul determines soul.Mend five kinds of strain and seven kinds of impairment, all be deficient, palpitation with fear, unhappy, forgetful.Logical nine orifices, sharp hundred arteries and veins, beneficial intensive culture gas, strengthening bone and muscle, separates cold and hot.

Side's solution of the present invention is: Flos Lonicerae, Fructus Forsythiae heat-clearing and toxic substances removing, wind-dispelling heat-dissipating in side, Folium Isatidis, Radix Isatidis heat-clearing and toxic substances removing, Rhizoma Phragmitis clearing away heat and promoting production of body fluid, the above five tastes are monarch drug altogether, fundamentally can carry out heat-clearing and toxic substances removing, anti-inflammation, can play certain antibacterial action to pneumonia from disease, also there is the effect of clearing away heat and promoting production of body fluid, wind-dispelling heat-dissipating simultaneously, the symptom of reduction of patient is carried out, the development of symptom management from symptom, thus the object reaching disease therapy.Folium Mori dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, Rhizoma Imperatae cooling blood for hemostasis, Radix Puerariae induces sweat and brings down a fever, Rhizoma Osmundae heat-clearing and toxic substances removing, Radix Asteris nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm, Semen Lepidii (Semen Descurainiae) eliminating pathogen from the lung for relieving asthma, Vascular aurantii activating QI to eliminate phlegm, above seven tastes are ministerial drug altogether, can assist a ruler in governing a country monarch drug heat-clearing and toxic substances removing, clearing away lung-heat and moistening for dryness, fundamentally nourishing the lung to keep the adverse QI downward can be carried out from patient, the symptom such as cough, pharyngalgia that reduction of patient occurs, strengthens patient's body constitution, accelerates the improvement of the state of an illness.Flos Farfarae nourishing the lung to keep the adverse QI downward, relieving cough and resolving phlegm, Bulbus Fritillariae Thunbergii heat clearing away eliminating stagnation, the cough-relieving of Semen Armeniacae Amarum (parched) sending down the abnormal ascending QI, Gypsum Fibrosum relieving restlessness is quenched the thirst, and Radix Peucedani falls apart wind heat clearing away, lowering the adverse-rising QI to resolve phlegm, Herba Houttuyniae, Herba Patriniae heat-clearing and toxic substances removing, Radix Platycodonis lung qi dispersing sore-throat relieving, Radix Angelicae Dahuricae wind dispelling cold expelling, Flos Chrysanthemi Indici heat-clearing and toxic substances removing, a few taste is adjuvant drug altogether above, there are broad-spectrum antiseptic and antiviral effect more, are equivalent to antibiotic medicine, and patient can not be made to produce drug resistance, and can resistance be improved, accelerate to recover.Radix Glycyrrhizae the spleen and stomach regulating, priming return through, for making medicine.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, has heat-clearing and toxic substances removing, wind-dispelling heat-dissipating, clearing away lung-heat and moistening for dryness, effect of bringing down a fever of inducing sweat, effectively can treat mycoplasma pneumoniae pneumonia.

Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Flos Lonicerae 25-35 part, Fructus Forsythiae 13-23 part, Folium Isatidis 15-25 part, Radix Isatidis 13-23 part, Rhizoma Phragmitis 25-35 part, Folium Mori 13-23 part, Rhizoma Imperatae 19-29 part, Radix Puerariae 10-20 part, Rhizoma Osmundae 7-17 part, Radix Asteris 10-20 part, Semen Lepidii (Semen Descurainiae) 7-17 part, Vascular aurantii 7-17 part, Flos Farfarae 7-17 part, Bulbus Fritillariae Thunbergii 7-17 part, Semen Armeniacae Amarum (parched) 7-17 part, Gypsum Fibrosum 25-35 part, Radix Peucedani 7-17 part, Herba Houttuyniae 15-25 part, Herba Patriniae 15-25 part, Radix Platycodonis 13-23 part, Radix Angelicae Dahuricae 10-20 part, Flos Chrysanthemi Indici 5-15 part, Radix Glycyrrhizae 4-14 part.

Wherein be preferably: Flos Lonicerae 30 parts, Fructus Forsythiae 18 parts, Folium Isatidis 20 parts, Radix Isatidis 18 parts, Rhizoma Phragmitis 30 parts, 18 parts, Folium Mori, Rhizoma Imperatae 24 parts, Radix Puerariae 15 parts, Rhizoma Osmundae 12 parts, Radix Asteris 15 parts, Semen Lepidii (Semen Descurainiae) 12 parts, Vascular aurantii 12 parts, Flos Farfarae 12 parts, Bulbus Fritillariae Thunbergii 12 parts, Semen Armeniacae Amarum (parched) 12 parts, Gypsum Fibrosum 30 parts, Radix Peucedani 12 parts, Herba Houttuyniae 20 parts, Herba Patriniae 20 parts, Radix Platycodonis 18 parts, the Radix Angelicae Dahuricae 15 parts, Flos Chrysanthemi Indici 10 parts, Radix Glycyrrhizae 9 parts.

A kind of preparation method for the treatment of the Chinese medicine preparation of mycoplasma pneumoniae pneumonia is as follows:

Step one: by weight proportion of the present invention, first becomes medicated bag by Semen Lepidii (Semen Descurainiae) bundle, is put in water and soaks about 45 minutes, filters, for subsequent use;

Step 2: by weight proportion of the present invention, grinds to 200 mesh sieves by Gypsum Fibrosum, Semen Armeniacae Amarum (parched), for subsequent use;

Step 3: by weight proportion of the present invention, by Radix Isatidis, Rhizoma Phragmitis, Rhizoma Imperatae, Radix Puerariae, Rhizoma Osmundae, Radix Asteris, Radix Peucedani, Radix Platycodonis, the Radix Angelicae Dahuricae is put into after marmite adds step one immersion and is remained cold water, exceed powder 2 ~ 5 centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 3 cm is added in residue medicinal residues, then Fructus Forsythiae is added, Folium Isatidis, Folium Mori, Bulbus Fritillariae Thunbergii, Herba Houttuyniae, medicated bag in Herba Patriniae and step one decocts about 30 minutes, add Flos Lonicerae afterwards, Vascular aurantii, Flos Farfarae, Flos Chrysanthemi Indici, Radix Glycyrrhizae decocts filtration in 20 minutes, obtain filtrate, merge twice filtrate, filter, waste, for subsequent use,

Step 4: gained medicine soup in step 3 is carried out concentrated add ethanol, place precipitation, filter, abandon precipitation, gained concentration of liquid medicine is the thick paste of relative density 1.15 ~ 1.20 under 75 DEG C of environment, by air-dry for thick paste pulverizing by filtrate recycling ethanol, add the powder in step 2, add Mel, antiseptic, wetting agent etc., carry out beating, rubbing, one-tenth ball, dry, be distributed into bag, both the honeyed pill for the treatment of mycoplasma pneumoniae pneumonia of the present invention.

Medicine of the present invention has heat-clearing and toxic substances removing, wind-dispelling heat-dissipating, clearing away lung-heat and moistening for dryness, effect such as to bring down a fever of inducing sweat, and it is evident in efficacy, cheap, have no side effect, not easily recur, safe ready, the mode that this Chinese medicine preparation adopts is treated and can be reduced the damage of Western medicine to patient's hepatic and renal function, accelerates the improvement of the state of an illness, adds up according to clinical 120 routine patient view, use medicine of the present invention the total effective rate course for the treatment of 90%, two the total effective rate course for the treatment of 95%.

Detailed description of the invention

Embodiment one, Flos Lonicerae 25 parts, Fructus Forsythiae 13 parts, Folium Isatidis 15 parts, Radix Isatidis 13 parts, Rhizoma Phragmitis 25 parts, 13 parts, Folium Mori, Rhizoma Imperatae 19 parts, Radix Puerariae 10 parts, Rhizoma Osmundae 7 parts, Radix Asteris 10 parts, Semen Lepidii (Semen Descurainiae) 7 parts, Vascular aurantii 7 parts, Flos Farfarae 7 parts, Bulbus Fritillariae Thunbergii 7 parts, Semen Armeniacae Amarum (parched) 7 parts, Gypsum Fibrosum 25 parts, Radix Peucedani 7 parts, Herba Houttuyniae 15 parts, Herba Patriniae 15 parts, Radix Platycodonis 13 parts, the Radix Angelicae Dahuricae 10 parts, Flos Chrysanthemi Indici 5 parts, Radix Glycyrrhizae 4 parts.

Embodiment two, Flos Lonicerae 30 parts, Fructus Forsythiae 18 parts, Folium Isatidis 20 parts, Radix Isatidis 18 parts, Rhizoma Phragmitis 30 parts, 18 parts, Folium Mori, Rhizoma Imperatae 24 parts, Radix Puerariae 15 parts, Rhizoma Osmundae 12 parts, Radix Asteris 15 parts, Semen Lepidii (Semen Descurainiae) 12 parts, Vascular aurantii 12 parts, Flos Farfarae 12 parts, Bulbus Fritillariae Thunbergii 12 parts, Semen Armeniacae Amarum (parched) 12 parts, Gypsum Fibrosum 30 parts, Radix Peucedani 12 parts, Herba Houttuyniae 20 parts, Herba Patriniae 20 parts, Radix Platycodonis 18 parts, the Radix Angelicae Dahuricae 15 parts, Flos Chrysanthemi Indici 10 parts, Radix Glycyrrhizae 9 parts.

Embodiment three, Flos Lonicerae 35 parts, Fructus Forsythiae 23 parts, Folium Isatidis 25 parts, Radix Isatidis 23 parts, Rhizoma Phragmitis 35 parts, 23 parts, Folium Mori, Rhizoma Imperatae 29 parts, Radix Puerariae 20 parts, Rhizoma Osmundae 17 parts, Radix Asteris 20 parts, Semen Lepidii (Semen Descurainiae) 17 parts, Vascular aurantii 17 parts, Flos Farfarae 17 parts, Bulbus Fritillariae Thunbergii 17 parts, Semen Armeniacae Amarum (parched) 17 parts, Gypsum Fibrosum 35 parts, Radix Peucedani 17 parts, Herba Houttuyniae 25 parts, Herba Patriniae 25 parts, Radix Platycodonis 23 parts, the Radix Angelicae Dahuricae 20 parts, Flos Chrysanthemi Indici 15 parts, Radix Glycyrrhizae 14 parts.

Here is the clinical statistics data that patient uses medicine of the present invention:

One, physical data and Therapeutic Method

Accept out-patient 120 example for medical treatment.According to Medications Example two of the present invention, and honeyed pill prepared by preferred preparation method, sooner or later service once, each 2, decoction being taken warmly.It within 10th, is a course for the treatment of.

Two, efficacy assessment standard

1, cure: mycoplasma pneumoniae pneumonia transference cure, other symptoms such as cough, pharyngalgia, nauseating, headache also disappear, and pathological examination is normal.

2, take a turn for the better: mycoplasma pneumoniae pneumonia symptom obviously alleviates, and body constitution is progressively recovered, and other clinical symptoms are also recovered gradually.

3, do not heal: mycoplasma pneumoniae pneumonia and other clinical symptoms are without any improvement.

Three, therapeutic outcome statistics

Have and above-mentionedly can to find out, Chinese medicine of the present invention has good clinical effectiveness at treatment mycoplasma pneumoniae pneumonia, effectively can improve the cure rate for the treatment of, be worth promoting in clinical practice.

Model case and curative effect:

Case one, Wu, female, 12 years old, patient's body constitution is always bad, in recent months, there is dyspnea in patient, cough, headache, and there is the sign increased the weight of, the head of a family and be flu, but aggravation at present, remove examination in hospital, be diagnosed as mycoplasma pneumoniae pneumonia, through antibiotic medicine symptomatic treatment, but effect is not clearly, made honeyed pill in the rear employing embodiment of the present invention two, after patient takes two courses for the treatment of, cough, pharyngalgia sensation obviously alleviates, breathe smooth and easy, spirit takes a turn for the better, breathe hard, weak phenomenon is also taken a turn for the better, climb building at ordinary times, obvious eupnea on foot, for consolidate curative effect, continue to take two courses for the treatment of, patient clinical phenomenon disappears completely, body constitution also strengthens gradually, remove examination in hospital, every inspection is all normal, recovery from illness.

Case two, in certain, man, 33 years old, cough, breathe hard, sometimes with heating, about there is the time of 3 months, also there are other uncomfortable phenomenons such as chest pain in the recent period, remove examination in hospital, be diagnosed as mycoplasma pneumoniae pneumonia, take antibiotic medicine and some symptomatic drugs, but effect is not clearly, here treatment afterwards, adopt made honeyed pill in the embodiment of the present invention two, after patient takes two courses for the treatment of, mycoplasma pneumoniae pneumonia sensation obviously alleviates, breathe smooth and easy, do not cough and do not breathe heavily, other symptoms are also controlled, continue to take a course for the treatment of, patient's mycoplasma pneumoniae pneumonia clinical symptoms disappears completely, body constitution also improves, follow up a case by regular visits to half a year, have no recurrence, recovery from illness.

Claims (4)

1. treat the Chinese medicine preparation of mycoplasma pneumoniae pneumonia for one kind, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Flos Lonicerae 25-35 part, Fructus Forsythiae 13-23 part, Folium Isatidis 15-25 part, Radix Isatidis 13-23 part, Rhizoma Phragmitis 25-35 part, Folium Mori 13-23 part, Rhizoma Imperatae 19-29 part, Radix Puerariae 10-20 part, Rhizoma Osmundae 7-17 part, Radix Asteris 10-20 part, Semen Lepidii (Semen Descurainiae) 7-17 part, Vascular aurantii 7-17 part, Flos Farfarae 7-17 part, Bulbus Fritillariae Thunbergii 7-17 part, Semen Armeniacae Amarum (parched) 7-17 part, Gypsum Fibrosum 25-35 part, Radix Peucedani 7-17 part, Herba Houttuyniae 15-25 part, Herba Patriniae 15-25 part, Radix Platycodonis 13-23 part, Radix Angelicae Dahuricae 10-20 part, Flos Chrysanthemi Indici 5-15 part, Radix Glycyrrhizae 4-14 part.

2. the Chinese medicine preparation of the treatment mycoplasma pneumoniae pneumonia according to claims 1, it is characterized in that, be made up of the medicine of following weight portion: Flos Lonicerae 30 parts, Fructus Forsythiae 18 parts, Folium Isatidis 20 parts, Radix Isatidis 18 parts, Rhizoma Phragmitis 30 parts, 18 parts, Folium Mori, Rhizoma Imperatae 24 parts, Radix Puerariae 15 parts, Rhizoma Osmundae 12 parts, Radix Asteris 15 parts, Semen Lepidii (Semen Descurainiae) 12 parts, Vascular aurantii 12 parts, Flos Farfarae 12 parts, Bulbus Fritillariae Thunbergii 12 parts, Semen Armeniacae Amarum (parched) 12 parts, Gypsum Fibrosum 30 parts, Radix Peucedani 12 parts, Herba Houttuyniae 20 parts, Herba Patriniae 20 parts, Radix Platycodonis 18 parts, the Radix Angelicae Dahuricae 15 parts, Flos Chrysanthemi Indici 10 parts, Radix Glycyrrhizae 9 parts.

3. the Chinese medicine preparation for the treatment of mycoplasma pneumoniae pneumonia according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is pill.

4. treat a preparation method for the Chinese medicine preparation of mycoplasma pneumoniae pneumonia, it is characterized in that, preparation method is as follows: step one: by weight proportion of the present invention, first Semen Lepidii (Semen Descurainiae) bundle is become medicated bag, is put in water and soaks about 45 minutes, filters, for subsequent use, step 2: by weight proportion of the present invention, grinds to 200 mesh sieves by Gypsum Fibrosum, Semen Armeniacae Amarum (parched), for subsequent use, step 3: by weight proportion of the present invention, by Radix Isatidis, Rhizoma Phragmitis, Rhizoma Imperatae, Radix Puerariae, Rhizoma Osmundae, Radix Asteris, Radix Peucedani, Radix Platycodonis, the Radix Angelicae Dahuricae is put into after marmite adds step one immersion and is remained cold water, exceed powder 2 ~ 5 centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 3 cm is added in residue medicinal residues, then Fructus Forsythiae is added, Folium Isatidis, Folium Mori, Bulbus Fritillariae Thunbergii, Herba Houttuyniae, medicated bag in Herba Patriniae and step one decocts about 30 minutes, add Flos Lonicerae afterwards, Vascular aurantii, Flos Farfarae, Flos Chrysanthemi Indici, Radix Glycyrrhizae decocts filtration in 20 minutes, obtain filtrate, merge twice filtrate, filter, waste, for subsequent use, step 4: gained medicine soup in step 3 is carried out concentrated add ethanol, place precipitation, filter, abandon precipitation, gained concentration of liquid medicine is the thick paste of relative density 1.15 ~ 1.20 under 75 DEG C of environment, by air-dry for thick paste pulverizing by filtrate recycling ethanol, add the powder in step 2, add Mel, antiseptic, wetting agent etc., carry out beating, rubbing, one-tenth ball, dry, be distributed into bag, both the honeyed pill for the treatment of mycoplasma pneumoniae pneumonia of the present invention.