CN104781394B - 用于培养间充质干细胞的方法 - Google Patents

用于培养间充质干细胞的方法 Download PDF

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CN104781394B
CN104781394B CN201380045750.4A CN201380045750A CN104781394B CN 104781394 B CN104781394 B CN 104781394B CN 201380045750 A CN201380045750 A CN 201380045750A CN 104781394 B CN104781394 B CN 104781394B
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cells
stem cells
mesenchymal stem
medium
cell therapy
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CN104781394A (zh
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梁允瑄
吴元
吴元一
权纯载
李美娟
田洪培
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Medipost Co Ltd
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    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
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    • C12N5/0602—Vertebrate cells
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    • C12N5/0662—Stem cells
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
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    • C12N2500/10—Metals; Metal chelators
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  • Orthopedic Medicine & Surgery (AREA)
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CN201380045750.4A 2012-09-03 2013-09-02 用于培养间充质干细胞的方法 Active CN104781394B (zh)

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KR1020120097193A KR101532556B1 (ko) 2012-09-03 2012-09-03 간엽줄기세포의 배양 방법
KR10-2012-0097193 2012-09-03
PCT/KR2013/007891 WO2014035215A1 (en) 2012-09-03 2013-09-02 Method for culturing mesenchymal stem cells

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EP (1) EP2893001B1 (cg-RX-API-DMAC10.html)
JP (1) JP6478243B2 (cg-RX-API-DMAC10.html)
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CN108359637B (zh) * 2018-02-14 2021-09-28 浙江生创精准医疗科技有限公司 一种宫血干细胞快速扩增的方法
CN109517786B (zh) * 2018-10-18 2022-06-17 广州元帅生物科技有限公司 一种具有修复功能的多能干细胞制剂及其应用
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WO2022004938A1 (ko) * 2020-06-30 2022-01-06 주식회사 미래셀바이오 유사 중간엽 줄기세포의 제조방법
CN112147340B (zh) * 2020-09-30 2024-03-08 北京银丰鼎诚生物工程技术有限公司 一种神经干细胞免疫调节功能的检测方法
CN112375733B (zh) * 2020-11-03 2022-09-02 中国人民解放军陆军军医大学第一附属医院 可增进间充质干细胞干细胞性的植物血凝素及其在间充质干细胞扩增培养中的应用
KR102435452B1 (ko) * 2020-11-11 2022-09-07 이엔셀 주식회사 노화가 감소되고 줄기세포능이 보존된 초기 중간엽 줄기세포, 및 그 배양방법
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CN113502261B (zh) * 2021-07-16 2023-08-29 上海东方星际干细胞科技有限公司 一种能高效分化成脂的规模化3d低氧间充质干细胞培养体系
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EP2893001A1 (en) 2015-07-15
CN104781394A (zh) 2015-07-15
US20150284686A1 (en) 2015-10-08
PL2893001T3 (pl) 2020-03-31
PT2893001T (pt) 2019-12-09
KR101532556B1 (ko) 2015-06-30
US10294456B2 (en) 2019-05-21
US9580687B2 (en) 2017-02-28
DK2893001T3 (da) 2019-12-02
CA2884000A1 (en) 2014-03-06
JP6478243B2 (ja) 2019-03-06
KR20140030703A (ko) 2014-03-12
AU2013309642B2 (en) 2018-10-25
WO2014035215A1 (en) 2014-03-06
US11332715B2 (en) 2022-05-17
ES2755802T3 (es) 2020-04-23
EP2893001A4 (en) 2016-03-09
IN2015DN01737A (cg-RX-API-DMAC10.html) 2015-05-29
US20190218517A1 (en) 2019-07-18
CA2884000C (en) 2021-08-24
US20170191036A1 (en) 2017-07-06
AU2013309642A1 (en) 2015-03-26
EP2893001B1 (en) 2019-10-30
JP2015532596A (ja) 2015-11-12

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