CN104619683B - 用于制备任选地取代的苯基和吡啶基吡咯烷类的方法 - Google Patents

用于制备任选地取代的苯基和吡啶基吡咯烷类的方法 Download PDF

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Publication number
CN104619683B
CN104619683B CN201380048737.4A CN201380048737A CN104619683B CN 104619683 B CN104619683 B CN 104619683B CN 201380048737 A CN201380048737 A CN 201380048737A CN 104619683 B CN104619683 B CN 104619683B
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China
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formula
compound
alkyl
iii
phenyl
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Expired - Fee Related
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CN201380048737.4A
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English (en)
Chinese (zh)
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CN104619683A (zh
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F.A.米尔陶
M.J.福特
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Bayer CropScience AG
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Bayer CropScience AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/02—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms
    • C07C317/10—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/14—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/01—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton
    • C07C323/02—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton having sulfur atoms of thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/07—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton having sulfur atoms of thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/16—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN201380048737.4A 2012-09-27 2013-09-25 用于制备任选地取代的苯基和吡啶基吡咯烷类的方法 Expired - Fee Related CN104619683B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12186243.7 2012-09-27
EP12186243 2012-09-27
PCT/EP2013/069919 WO2014048958A1 (en) 2012-09-27 2013-09-25 Process for the preparation of optionally substituted phenyl and pyridyl pyrrolidines

Publications (2)

Publication Number Publication Date
CN104619683A CN104619683A (zh) 2015-05-13
CN104619683B true CN104619683B (zh) 2017-05-10

Family

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CN201380048737.4A Expired - Fee Related CN104619683B (zh) 2012-09-27 2013-09-25 用于制备任选地取代的苯基和吡啶基吡咯烷类的方法

Country Status (13)

Country Link
US (1) US9447036B2 (enExample)
EP (1) EP2900634B1 (enExample)
JP (1) JP6251749B2 (enExample)
KR (1) KR20150059778A (enExample)
CN (1) CN104619683B (enExample)
BR (1) BR112015006825A2 (enExample)
DK (1) DK2900634T3 (enExample)
ES (1) ES2625547T3 (enExample)
IL (1) IL237749A (enExample)
IN (1) IN2015DN02542A (enExample)
MX (1) MX350575B (enExample)
TW (1) TWI601713B (enExample)
WO (1) WO2014048958A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111032617B (zh) * 2017-08-09 2023-02-24 阿尔萨达股份公司 制备4-(七氟-2-丙基)苯胺的方法

Citations (2)

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WO2008128711A1 (en) * 2007-04-23 2008-10-30 Bayer Cropscience Ag Insecticidal aryl pyrrolidines
WO2011080211A1 (en) * 2009-12-28 2011-07-07 Bayer Cropscience Ag Pesticidal arylpyrrolidines

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ATE128466T1 (de) 1989-04-17 1995-10-15 Bayer Ag Verfahren zur herstellung von 2,7- diazabicyclo(3.3.0)octanen.
IT1274021B (it) 1994-02-28 1997-07-14 Italfarmaco Spa Diesteri dell'acido carbonico ad attivita' antivirale ed antinfiammatoria
DK0863857T3 (da) 1995-11-23 2002-11-04 Rhodia Chimie Sa Fremgangsmåde til perfluoralkylering og reaktant til iværksættelse af denne fremgangsmåde
WO1998006694A1 (en) * 1996-08-16 1998-02-19 Du Pont Pharmaceuticals Company Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof
MY137509A (en) 2002-05-28 2009-02-27 Dimensional Pharm Inc Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions
US7230119B2 (en) 2004-08-25 2007-06-12 Biocryst Pharmaceuticals, Inc. Process for the preparation of substituted pyrrolidine derivatives and intermediates
US7521427B2 (en) 2004-11-09 2009-04-21 Georgia Tech Research Corporation Peptidyl allyl sulfones
AR057032A1 (es) 2005-05-27 2007-11-14 Wyeth Corp Tigeciclina y metodos de preparacion
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WO2011080211A1 (en) * 2009-12-28 2011-07-07 Bayer Cropscience Ag Pesticidal arylpyrrolidines

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Also Published As

Publication number Publication date
EP2900634A1 (en) 2015-08-05
KR20150059778A (ko) 2015-06-02
WO2014048958A1 (en) 2014-04-03
MX350575B (es) 2017-09-11
IL237749A (en) 2017-09-28
US9447036B2 (en) 2016-09-20
MX2015003902A (es) 2015-07-17
CN104619683A (zh) 2015-05-13
EP2900634B1 (en) 2017-02-22
ES2625547T3 (es) 2017-07-19
IN2015DN02542A (enExample) 2015-09-11
TW201418215A (zh) 2014-05-16
US20150246880A1 (en) 2015-09-03
JP6251749B2 (ja) 2017-12-20
BR112015006825A2 (pt) 2017-08-08
DK2900634T3 (en) 2017-05-22
TWI601713B (zh) 2017-10-11
JP2015535835A (ja) 2015-12-17

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Termination date: 20190925