CN104547507B - It is a kind of to reduce somatic number in milk cow's milk and promote newborn Chinese prescription - Google Patents

Abstract

The invention discloses a traditional Chinese medicine powder formula for reducing the number of somatic cells in cow's milk and promoting lactation. The prescription of the present invention is composed by weight: Astragalus 40-100g, Codonopsis 30-90g, Angelica 10-40g, Radix Ophiopogon japonicus 10-30g, Tangerine stone 10-30g, Buliuxing 10-50g, Silverflower rattan 20-60g, Dandelion 20‑60g, whole Trichosanthes 10‑20g, red peony 10‑40g, raw licorice 10‑30g, green bark 10‑40g, motherwort 10‑40g, tangerine peel 10‑30g, etc. Its preparation method crushes 14 Chinese herbal medicines through an 80-mesh sieve, the particle size reaches 180 μm, and packs them separately to obtain the finished product; the invention is a pure Chinese herbal medicine prescription without adding any industrial raw materials, which is safe and reliable; the invention can effectively reduce milk Somatic cell count, increase milk yield and milk quality, and low cost, simple production process, has a good prospect for popularization and application.

Description

A traditional Chinese medicine prescription for reducing the number of somatic cells in dairy cow milk and promoting lactation

technical field

The invention belongs to the field of Chinese herbal medicine products, and relates to the preparation and application of a traditional Chinese medicine powder formula for reducing the number of somatic cells in cow milk and promoting lactation.

technical background

The content of somatic cells in milk is an important indicator for judging whether cows suffer from subclinical mastitis. The country has issued corresponding standards for the determination of somatic cells in milk. Cow recessive mastitis, also known as subclinical or atypical mastitis, is a common intractable disease in dairy cows, and it is the first of the three major diseases (mastitis, metritis, limb and foot disease) that plague the dairy farming industry. At present, there are about 231 million dairy cows in the world, and about 33.3% of them suffer from various types of mastitis. Recessive mastitis in dairy cows not only affects milk production and milk quality, prolongs calving intervals, etc., but also affects human health, causing greater losses to the dairy industry and seriously affecting the economic benefits of dairy cattle owners. According to data records, the incidence of recessive mastitis in dairy cows is generally 50%-70%, and the milk production of cows with recessive mastitis decreases by about 15%. The economic loss caused by recessive mastitis is as high as 2 billion US dollars every year in the world, and the direct economic loss caused by it in my country is as high as 300 million yuan.

Up to now, antibiotic therapy is mainly used in the control of recessive mastitis in dairy cows. Prolonged abuse of antibiotics leads to the emergence of drug-resistant strains, which in turn reduces the therapeutic effect of antibiotics. Since people are paying more and more attention to food safety issues, and antibiotic residues in milk seriously affect people's health, it is particularly important to seek a green, healthy and residue-free method for preventing and treating recessive mastitis in dairy cows. As a substitute for antibiotics, Chinese herbal medicine has attracted much attention for its advantages of naturalness, no residue, less toxic and side effects, and no drug resistance. After searching, it is found that there are some traditional Chinese medicine prescriptions related to the treatment of cow mastitis, but the above traditional Chinese medicine prescriptions have some shortcomings. 1. Some traditional Chinese medicine prescriptions need to be fed, which is time-consuming and laborious; 2. Some traditional Chinese medicine prescriptions are effective for prevention and treatment Mastitis has a certain effect, but there is no report on milk quality and milk production.

The invention provides a traditional Chinese medicine prescription for reducing the number of somatic cells in cow's milk and promoting lactation. Raw licorice, green bark, motherwort, tangerine peel for prescription. Astragalus membranaceus is warm in nature, absorbs sweat and strengthens the surface, supports sores and muscles, promotes yang and invigorates qi; Codonopsis sweet and flat, nourishes the middle and nourishes qi, quenches thirst and produces body fluid; angelica is sweet and warm, produces blood and invigorates the heart, supports deficiency and damage, expels blood stasis and promotes regeneration; Ophiopogon japonicus is sweet in taste, nourishing yin and promoting body fluid, nourishing lung and clearing heart; orange core is bitter in taste, dredging collaterals and dispelling stagnation; Dandelion is bitter in taste, clears heat and detoxifies, reduces swelling and dissipates stagnation; whole melon is sweet in taste, moistens lungs and broadens chest, clears away heat and resolves phlegm, moistens intestines and laxative; Tonifying middle and replenishing qi, clearing heat and detoxifying, eliminating phlegm and relieving cough, relieving spasm and relieving pain, reconciling medicinal properties; Qingpi is bitter and warm, can attack qi stagnation, cut hard and calm liver, soothe the stomach and eat; Swelling and pain; tangerine peel is pungent and warm, smoothes the Qi and widens the diaphragm, leaves white to harmonize the stomach, eliminates phlegm and white.

This prescription has the effects of clearing heat and detoxifying, promoting blood circulation and removing blood stasis, increasing milk and dispelling stagnation, invigorating qi and nourishing blood, and dredging meridians. The preparation is simple and the feeding is convenient. It has been proved by clinical trials that its formula can effectively reduce the number of somatic cells in milk, promote lactation, improve milk quality, and increase milk production.

Contents of the invention

The invention provides a traditional Chinese medicine prescription for reducing the number of somatic cells in milk of cows and promoting lactation, which can significantly reduce the number of somatic cells in milk, effectively prevent recessive mastitis of cows, and improve milk production and milk quality of cows.

In order to achieve the above object, the technical solution adopted by the present invention is as follows.

A traditional Chinese medicine prescription for reducing the number of somatic cells in cow milk and promoting lactation, which is composed of the following raw materials in the weight ratio: 40-100g of astragalus, 30-90g of Codonopsis pilosula, 10-40g of angelica, 10-30g of Radix Ophiopogon japonicus, and 10 orange cores -30g, Wangbuliuxing 10-50g, Yinhuateng 20-60g, Dandelion 20-60g, Whole Trichosanthes 10-20g, Radix Paeoniae Rubra 10-40g, Raw Licorice 10-30g, Qingpi 10-40g, Motherwort 10-40g , Chenpi 10-30g.

Preferred are: Astragalus 60g, Codonopsis 50g, Angelica 20g, Ophiopogon japonicus 15g, Tangerine core 15g, Wangbuliuxing 20g, Yinhuateng 30g, Dandelion 30g, Whole Trichosanthes 10g, Radix Paeoniae Rubra 20g, Raw licorice 15g, Qingpi 20g, Motherwort 20g, tangerine peel 15g.

The present invention also includes a preparation method of the composition of the present invention, comprising the following steps.

Grind astragalus, codonopsis, angelica, Ophiopogon japonicus, tangerine core, wangbuliuxing, silver flower vine, dandelion, whole melon, red peony root, raw licorice, green skin, motherwort, and tangerine peel, pass through a 80-mesh sieve, and mix according to the formula ratio , stir well, that is. It is also possible to mix the 14 traditional Chinese medicines according to the formula ratio and then pulverize them and pass through an 80-mesh sieve.

The invention fully exposes the active ingredients in the medicinal material through pulverization, which is beneficial to the digestion and absorption of the active ingredients, greatly improves the utilization of the bioactive substances of the Chinese herbal medicine, saves the resources of the Chinese herbal medicine, and improves the curative effect. This formula is easy to use, can be fed with mixed materials, and can also be fed with water, which is conducive to the popularization and application of this formula.

detailed description

The following examples only illustrate the present invention in further detail, but these examples are not intended to limit the protection scope of the present invention.

Implementation example 1, the traditional Chinese medicine prescription in this example is composed of the following raw materials in weight ratio: Astragalus 60g, Codonopsis 50g, Angelica 20g, Radix Ophiopogon japonicus 15g, Orange core 15g, Wangbuliuxing 20g, Yinhuateng 30g, Dandelion 30g , Whole Trichosanthes 10g, Radix Paeoniae Rubra 20g, Raw Licorice 15g, Green Peel 20g, Motherwort 20g, Tangerine Peel 15g. Each component is pulverized separately, passed through an 80-mesh sieve, and mixed according to the above ratio to obtain a powder.

Example 2, the traditional Chinese medicine prescription in this example is composed of the following raw materials in weight ratio: Astragalus 65g, Codonopsis 40g, Angelica 20g, Radix Ophiopogon japonicus 15g, Tangerine core 15g, Buliuxing 30g, Yinhuateng 35g, Dandelion 25g , Whole Trichosanthes 10g, Radix Paeoniae Rubra 15g, Raw Licorice 15g, Green Peel 18g, Motherwort 17g, Tangerine Peel 20g. Each component is pulverized separately, passed through an 80-mesh sieve, and mixed according to the above ratio to obtain a powder.

Implementation case 3, drug efficacy experiment.

Experimental method: The California mastitis test method (CMT) was used to conduct a preliminary screening from the lactating cows of Xinjiang Western Animal Husbandry Co., Ltd., and the positive cows with a test result of "++" were tested by a somatic cell analyzer, and the body cells were selected. 40 dairy cows with more than 600,000 cells/mL were used as experimental samples, 30 of which were used as the experimental group, and were randomly divided into two groups, and the remaining 10 were used as the control group. Experimental groups 1 and 2 were respectively fed with the corresponding powders in Examples 1 and 2 at a dose of 170 g/head/d for 10 days. The control group received no drug administration, and the rest of the feeding conditions were the same. The number of somatic cells in the milk and physical and chemical indicators (milk protein, milk fat and non-fat milk solids, freezing point) were measured before and after the experiment, and the milk production of each head was recorded by computer. During the experiment, the feeding progress, mental state and drinking water of each cow were observed.

Experimental results: as can be seen from Table 1, the Chinese medicine prescription of the present invention has a significant impact on the number of somatic cells in the milk of cows suffering from subclinical mastitis. Before the experiment, the number of somatic cells in the experimental group exceeded 1 million/mL. After the prescription of traditional Chinese medicine, the number of somatic cells in the two experimental groups decreased significantly (P < 0.01), meeting the requirements of the industry standard pollution-free food in fresh milk (NY 5045-2008) (≤600,000/mL), while the control group Somatic cells showed an increasing trend after the experiment.

It can be seen from Table 2 that the milk production of experimental groups 1 and 2 increased significantly by 21.2% and 24.6% respectively (P < 0.05) compared with the pre-experimental levels when the traditional Chinese medicine formula was used to treat dairy cows with recessive mastitis. The change of milk production is not obvious, which shows that the traditional Chinese medicine formula has a therapeutic effect on cow recessive mastitis, and at the same time can promote lactation of cows and increase milk production.

It can be seen from Table 3 that the protein, fat and non-fat milk solids and relative density in the milk of the experimental group were higher than those before the treatment, and the physical and chemical indicators in the milk of the control group did not change significantly before and after the test, indicating that the traditional Chinese medicine prescription can improve Increase milk production and improve milk quality.

The embodiment proves that the traditional Chinese medicine prescription prepared by the invention can significantly reduce the number of milk cells in dairy cows, effectively treat subclinical mastitis, and improve the milk production and quality of dairy cows.

Claims (4)

1. a kind of Chinese medicine composition for reducing somatic number in milk cow's milk and promoting breast, it is characterised in that the Chinese medicine composition is： Radix Astragali 60g, Radix Codonopsis 50g, Radix Angelicae Sinensis 20g, tuber of dwarf lilyturf 15g, tangerine core 15g, seed of cowherb 20g, honeysuckle stem 30g, dandelion 30g, full melon Beach wormwood 10g, radix paeoniae rubrathe 20g, licorice 15g, rascal 20g, motherwort 20g, dried orange peel 15g；

The Chinese medicine composition of somatic number and rush breast is prepared into by following preparation methods in a kind of described reduction milk cow's milk Arrive：（1）The Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, the tuber of dwarf lilyturf, tangerine core, the seed of cowherb, honeysuckle stem, dandelion, full Snakegourd Fruit, the radix paeoniae rubrathe, licorice is blue or green Skin, motherwort, dried orange peel crush respectively, cross 80 mesh sieves, mix, produce by composition ratio；（2）Also can by 14 taste medicinal materials press than Crushed after example mixing, cross 80 mesh sieves, produce.

2. the Chinese medicine composition of somatic number and rush breast in a kind of reduction milk cow's milk according to claim 1, manufactured system Agent is powder.

3. the Chinese medicine composition of somatic number and rush breast in a kind of reduction milk cow's milk according to claim 1, it is characterized in that The Chinese medicine composition can be used for the additive of milk cow to be directly appended in feed.

4. the Chinese medicine composition of somatic number and rush breast in a kind of reduction milk cow's milk according to claim 1, its feature It is that the Chinese medicine composition can reduce somatic number in milk cow's milk and promote lactation, for preventing, treating the recessive mastitis of milk cow With the raising milk cow in lactation period output of milk.