CN105267301A - Traditional Chinese medicine composition for reducing somatic cell count of dairy cows and its preparation method - Google Patents

Traditional Chinese medicine composition for reducing somatic cell count of dairy cows and its preparation method Download PDF

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Publication number
CN105267301A
CN105267301A CN201510808207.6A CN201510808207A CN105267301A CN 105267301 A CN105267301 A CN 105267301A CN 201510808207 A CN201510808207 A CN 201510808207A CN 105267301 A CN105267301 A CN 105267301A
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parts
chinese medicine
medicine composition
reducing
traditional chinese
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陆凤琪
陈文成
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Anhui Muchuntang Natural Medicine Research Development Co Ltd
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Anhui Muchuntang Natural Medicine Research Development Co Ltd
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Priority to CN201510808207.6A priority Critical patent/CN105267301A/en
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Abstract

The invention relates to a traditional Chinese medicine composition for reducing somatic cell count of dairy cows and its preparation method. The traditional Chinese medicine composition is made from following Chinese medicinal materials by weight: Radix Condonopsis Lanceolatae 2-4 parts, Semen Vaccariae (roasted) 3-5 parts, Caulis Spatholobi 3-6 parts, Radix Scutellariae 2-3 parts, Herba Taraxaci 3-5 parts, and Herba Ecliptae 4-6 parts. The traditional Chinese medicine composition is capable of reducing the somatic cell count, reducing clinical incidence of mastitis and increasing milk production.

Description

A kind of Chinese medicine composition increased for reducing dairy cow milk somatic number and preparation method thereof
(1) technical field
The present invention relates to Chinese medicine composition, be specifically related to a kind of Chinese medicine composition increased for reducing dairy cow milk somatic number and preparation method thereof.
(2) background technology
Somatic number (SomaticCellCounts, SCC) refers to somatic cell quantity contained in every ml milk, comprises the isocellular summation of phagocyte, lymphocyte, Exfoliative cells and neutrophilic leukocyte.Its reflection cattle farm cow breast health status.In milk, somatic number is within 200,000/ml under normal circumstances, and wherein neutrophilic leukocyte percentage ratio is 0 ~ 11%, macrophage 66 ~ 88%, lymphocyte 10 ~ 27%, cast epithelial cell 0 ~ 7%.When mammary gland is infected or after damage, in milk, somatic number will rise, and wherein polymorph neutrophile leucocytes proportion can up to more than 95%.
In milk somatic number number be subject to perhaps multifactorial impact.As the milch cow age, lactation period length, courses of infection, Milking time etc.But in the short time, the change that is exceedingly fast of somatic number is inflamed because of cow mammary gland often, and the infection of pathogenic bacteria is its main cause.Because of the intrusion of microorganism, breast regional blood flow is increased, and vascular permeability is hyperfunction, causes neutrophilic leukocyte etc. having the local ionization of inflammation, and in milk, cell number and kind there occurs change.
In milk, somatic number increases and has a huge impact milk-quality, causes dairy fat content to reduce, and lactose content reduces and dry matter content decline.Because tissue has the necrosis of respective degrees and pathogenic bacterium etc., be decomposed generation nitrogen-containing compound, causes Protein Content in Milk to raise, but the aminoacid in milk, particularly essential amino acid reduces as tyrosine equal size, therefore causes total trophic level to be decline.Due to the decline of milk-quality, cause serious economic loss.
Clinical symptoms is not had because Contents in Cows cell number increases majority, and it is residual to adopt antibiotic therapy easily to produce, cause larger economic loss, therefore most of Contents in Cows cell number increases and does not treat clinically, main or undertaken controlling by feeding and management.The clinical treatment also Chinese herbal medicine that adopts carries out more, the medicine that current Clinical practice is maximum improves immunity of organisms for master, but from mechanism, why Contents in Cows cell number increases is hyperfunction due to immunity of organisms, produce a large amount of macrophage in order to eliminate pathogenic microorganism and virulence factor in mammary gland, thus the most clinical effectiveness of existing prescription is unstable.Prescription of the present invention looks for another way, and the medical material of employing heat-clearing and toxic substances removing, lactogenesis of invigorating blood circulation carries out compatibility, increases disease all effective for most somatic number.
(3) summary of the invention
The object of the present invention is to provide one can reduce Contents in Cows cell number, improve the compound Chinese medicinal preparation of milk yield.
For achieving the above object, the technical solution used in the present invention is as follows:
For reducing the Chinese medicine composition that dairy cow milk somatic number increases, be made up of the raw material of Chinese medicine of following portions by weight:
Radix Codonopsis Lanceolatae 2 ~ 4 parts, Semen Vaccariae (stir-fry) 3 ~ 5 parts, Caulis Spatholobi 3 ~ 6 parts, Radix Scutellariae 2 ~ 3 parts, Herba Taraxaci 3 ~ 5 parts, Herba Ecliptae 4 ~ 6 parts.
Described Chinese medicine composition each raw material of Chinese medicine is pulverized respectively rear mistake 200 mesh sieve to be obtained by mixing.
The present invention increases this clinical symptoms to dairy cow milk somatic number; from organic conception; and in conjunction with pathogeny; use heat and toxic materials clearing away medicine with the reaction that reduces inflammation; improve the permeability of microvessel cell film, less leukocyte infiltration, lactogenesis medicine of invigorating blood circulation promotes galactopoiesis; improve mammary gland lactogenic function, then be equipped with Radix Scutellariae with keep-alive blood not damaging fetus.
(4) detailed description of the invention:
Technical scheme of the present invention is further described below in conjunction with detailed description of the invention, but described in claimed scope is not limited to.
Formula: Radix Codonopsis Lanceolatae 3 parts, Semen Vaccariae (stir-fry) 3 parts, Caulis Spatholobi 4 parts, Radix Scutellariae 2 parts, Herba Taraxaci 4 parts, Herba Ecliptae 4 parts.
Method for making: each raw material of Chinese medicine is pulverized respectively the medicament that rear mistake 200 mesh sieve is obtained by mixing, obtain Chinese medicine composition.
Above-mentioned Chinese medicine composition has been carried out Comparison of clinical effect test in cattle farm, and concrete grammar is as follows:
For examination place one: Wuqing District, Tianjin dairy village.
For examination cows: select breast without the milch cow of obvious clinical symptoms, draw by profit and cut down somatic cell detector and detect single newborn district somatic number and enter test the milch cow of 500,000/more than ml, to enter to try milch cow and be divided into 2 groups by average body cell number is similar, be respectively test group and matched group.Test group every cow head to be fed this invention Chinese medicine composition 100g every day, and use 1 week continuously, matched group does not do any process.Within the 3rd day, the 5th day and the 7th day before medication, after medication, measure somatic number in the ill newborn district of milch cow respectively, and test the milk yield of milch cow before adding up medication and after medication, analysis of making comparisons.
Somatic number result of variations sees the following form.
Table 1 Contents in Cows cell number test result (ten thousand/ml)
Group Before medication After medication the 3rd day After medication the 5th day After medication the 7th day
Test group 78.3±18.6 53.4±16.8a 42.8±14.3A 30.5±12.7A
Matched group 79.6±16.4 78.7±18.4b 72.6±16.9B 69.3±17.6B
Note: lower case difference represents significant difference (P < 0.05); Capitalization difference represents that difference extremely significantly (P < 0.01).
The above results illustrates, medicine of the present invention uses 3 days continuously, and Contents in Cows cell number declines significantly, with matched group comparing difference remarkable (P < 0.05); Continuous use more than 5 days, with the poor heteropole of matched group remarkable (P < 0.01).
Milk yield result of variations sees the following form.
Table 2 milk production of cow test result (kg)
Group Before medication After medication
Test group 18.9±3.8 21.5±3.2a
Matched group 19.1±3.4 18.4±2.9b
The above results illustrates, medicine of the present invention not only has reduction somatic number, and has lactogenesis of enriching blood, and promotes the effect of milk yield, with matched group comparing difference remarkable (P < 0.05).
For examination place two: Qingdao milch cow demonstration plant.
For examination cows: select the cows that milk yield is similar, according to milking, order is divided into 2 groups, is respectively test group 60 and matched group 58.This invention Chinese medicine composition of test group full group's spice administration 100g, use 1 week continuously, matched group does not do any process.Before medication and after medication, adopt CMT detection liquid cows to be carried out to the detection of latent mammitis respectively, and carried out the diagnosis of clinical mastitis by clinical symptoms.
Latent mammitis testing result sees the following form.
The testing result of table 3 cows latent mammitis
The above results illustrates, medicine of the present invention uses 1 week continuously, can reduce the recall rate of jumpbogroup bovine subclinical mastitis.
Clinical mastitis testing result sees the following form.
The testing result of the clinical mastitis of table 4 cows
Group Head number Before medication (head) After medication (head) Sickness rate (%)
Test group 60 0 1 1.67
Matched group 58 0 3 5.17
The above results illustrates, medicine of the present invention uses 1 week continuously, can reduce the sickness rate of the clinical mastitis of jumpbogroup milch cow.
In sum, Chinese medicine composition of the present invention dairy cow milk somatic number is increased, milk yield decline there is good therapeutic effect.

Claims (4)

1. for reducing the Chinese medicine composition that dairy cow milk somatic number increases, it is characterized in that: be made up of the raw material of Chinese medicine of following portions by weight:
Radix Codonopsis Lanceolatae 2 ~ 4 parts, Semen Vaccariae (stir-fry) 3 ~ 5 parts, Caulis Spatholobi 3 ~ 6 parts, Radix Scutellariae 2 ~ 3 parts, Herba Taraxaci 3 ~ 5 parts, Herba Ecliptae 4 ~ 6 parts.
2. a kind of Chinese medicine composition increased for reducing dairy cow milk somatic number according to claim 1, is characterized in that: the parts by weight of described raw material of Chinese medicine are:
Radix Codonopsis Lanceolatae 3 parts, Semen Vaccariae (stir-fry) 3 parts, Caulis Spatholobi 4 parts, Radix Scutellariae 2 parts, Herba Taraxaci 4 parts, Herba Ecliptae 4 parts.
3., according to the arbitrary described a kind of Chinese medicine composition increased for reducing dairy cow milk somatic number of claim 1 ~ 2, it is characterized in that: described Chinese medicine composition each raw material of Chinese medicine is pulverized respectively rear mistake 200 mesh sieve to be obtained by mixing.
4., according to the arbitrary described a kind of Chinese medicine composition increased for reducing dairy cow milk somatic number of claim 1 ~ 2, it is characterized in that: with above-mentioned Chinese medicine composition for raw material is prepared into oral liquid and granule.
CN201510808207.6A 2015-11-23 2015-11-23 Traditional Chinese medicine composition for reducing somatic cell count of dairy cows and its preparation method Pending CN105267301A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105833035A (en) * 2016-05-31 2016-08-10 中国农业科学院兰州畜牧与兽药研究所 Traditional Chinese medicine composition for reducing quantities of somatic cells in milk of dairy cows, method for preparing traditional Chinese medicine composition and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103263532A (en) * 2013-05-31 2013-08-28 河北围场金发动物药品有限公司 Medicament for reducing somatic cell count in milk and preparation method
CN104547507A (en) * 2013-10-14 2015-04-29 新疆农垦科学院 Traditional Chinese medicine prescription for reducing number of somatic cells in dairy cow milk and promoting milk production

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103263532A (en) * 2013-05-31 2013-08-28 河北围场金发动物药品有限公司 Medicament for reducing somatic cell count in milk and preparation method
CN104547507A (en) * 2013-10-14 2015-04-29 新疆农垦科学院 Traditional Chinese medicine prescription for reducing number of somatic cells in dairy cow milk and promoting milk production

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
丁伯良等: "《奶牛乳房炎》", 31 January 2011, 中国农业出版社 *
王子敬等: ""复方中草药添加剂对奶牛隐性乳房炎及奶产量的影响"", 《畜牧兽医科技信息》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105833035A (en) * 2016-05-31 2016-08-10 中国农业科学院兰州畜牧与兽药研究所 Traditional Chinese medicine composition for reducing quantities of somatic cells in milk of dairy cows, method for preparing traditional Chinese medicine composition and application thereof

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Application publication date: 20160127