CN102919566B - Chinese medicinal feed additive for improving milk yield of cow and preparation method thereof - Google Patents

Chinese medicinal feed additive for improving milk yield of cow and preparation method thereof Download PDF

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CN102919566B
CN102919566B CN 201210379377 CN201210379377A CN102919566B CN 102919566 B CN102919566 B CN 102919566B CN 201210379377 CN201210379377 CN 201210379377 CN 201210379377 A CN201210379377 A CN 201210379377A CN 102919566 B CN102919566 B CN 102919566B
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feed additive
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CN102919566A (en
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董发明
邱妍
张晓锋
王建平
李元晓
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Henan University of Science and Technology
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Abstract

The invention discloses a Chinese medicinal feed additive for improving milk yield of cow and a preparation method thereof, and belongs to the field of livestock additives. The additive comprises the following raw materials in part by weight: 15 to 25 parts of codonopsis pilosula, 15 to 25 parts of Chinese angelica, 25 to 35 parts of fructus ligustri lucidi, 35 to 45 parts of folium isatidis, 15 to 25 parts of dandelion, 15 to 25 parts of common andrographis herb, and 5 to 15 parts of liquoric root. Based on theory of tradition Chinese medicine, the additive is made of pure Chinese medicines.By combination of the seven Chinese medicines which have effects of clearing away heat and toxic materials, eliminating carbuncles and stasis, reinforcing qi and nourishing blood, stimulating the menstrual flow and promoting milking, the Chinese medicinal feed additive is safe to eat, does not have any side effect, has the functions of eliminating bacteria diminishing inflammation, improving immunity in organisms, effectively preventing cow recessive mastitis in cow and obviously increasing milk yield, does not have side effect on milk quality. The additive is simple in formula, economic and practical and is suitable for industrial production, application and popularization.

Description

A kind of Chinese herbal feed additive that improves milk production of cow and preparation method thereof
Technical field
The present invention relates to a kind of Chinese herbal feed additive, be specifically related to a kind of Chinese herbal feed additive that improves milk production of cow and preparation method thereof, belong to the animal feeding-stuff additive agent field.
Background technology
Development along with China's intensive culture industry and feed industry, the application of feed addictive is increasingly extensive, the continuous appearance of the drug resistance that produces for antibiotic simultaneously and the problem such as residual in animal products thereof is so that the cry of development Substitutes For Antibiotic also grows to even greater heights.People turn to sight some natural feed addictives gradually, Chinese herb feed additive is according to Chinese veterinarian's pharmacology opinion scientific composition, be used for increasing milk, its unique advantage is arranged, as ruminant, high to the medicinal plant utilization rate, Chinese medicine can not only be as nutrient utilization, and its pharmacological action of performance in utilization.This pharmacological action diverse in function, toxic and side effect is little, does not produce drug resistance, and is not residual in vivo, resistance milk do not occur, caused the broad interest of Chinese scholars.Chinese herbal medicine has become a large focus of Animal nutrition research direction, the Devoting Major Efforts To Developing Chinese herbal feed additive is for improving production performance, solve the antibiotic residue problem, development stockbreeding industry, satisfy people to the demand of food security, strengthen China's animal products in the competitiveness of international market, have important economic implications and social benefit.
Mastitis for milk cows is the stubborn disease that the most common a kind of multiple harm milk cow produces and is difficult for thoroughly curing, and it not only affects output and the quality of milk, and affects the rate of oestrusing and the pregnancy rate of milk cow, perplexs the sound development of dairy industry always.Comparatively speaking, recessive mastitis is more general in the milk cows, accounts for 75%~95% of morbidity sum, even in the higher country of raise competence, the incidence of disease of recessive mastitis is also more than 50%.Owing to suffer from changing without obvious of cow's milk room and the sight of milk naked eyes, be difficult for clinically finding, and China's most areas not yet cause enough attention, lacks the monitoring means of necessity, virtually produces to bring than large economy to milk cow and loses.
Chinese medicine is used for improving the existing a lot of reports in milk cow production performance aspect as feed addictive, has also obtained certain clinical effectiveness.It is generally acknowledged that increasing milk Chinese medicine has certain trophism, contain milk cow grow necessary protein, amino acid, fat, vitamin, mineral matter, trace element etc., and the glycolysis by microorganism to become can be the nutriment that body absorbs, promote protein and Enzyme Production, improve the output of milk.Increase milk Chinese medicine and have simultaneously immunocompetence, its immune effective active composition is mainly polysaccharide, glucoside, alkaloid, volatile ingredient and organic acid etc., can strengthen the immunologic function of body, the excitating organism vigor, can also promote the anaerobic bacteria growth, regulate the micro ecology of gastrointestinal tract balance, improve the utilization rate of feed, thereby improve production performance.Some traditional Chinese medicinal components also contains some parahormone sample materials, can play the regulating action of hormonelike to body, strengthens body to the regulative mechanism of lactation, promotes the mammary glandular cell anabolism, plays to increase the breast effect." Chinese animal doctor's magazine " discloses a kind of Traditional Chinese medicinal milk-increasing powder formula in the 6th phase in 1993 " the fodder for increasing milk health-care agent increases the loose research of breast ", formed by the 10 flavor Chinese medicines such as Radix Codonopsis, Radix Angelicae Sinensis, the Radix Astragali, the root of herbaceous peony, be used in conjunction administration 21 days with the 180g/ consumption per day, the incidence of cow subclinical mastitis significantly reduces 13.96%(P<0.01 before than medication after the medication), average daily milk yield improves about 1.27kg.
Yet the defectives such as the Chinese herbal feed additive ubiquity flavour of a drug that use in the at present milk cow production are on the high side, cost is higher, the medicine interpolation time is long can not effectively be prevented the generation of cow subclinical mastitis and be improved milk production of cow.Therefore, be badly in need of a kind of Chinese herbal feed additive that can significantly improve milk production of cow, prevention cow subclinical mastitis disease and then improve milk quality.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese herbal feed additive that improves milk production of cow, by in the daily ration of lactating cow, adding this Chinese medicine preparation, effectively bring into play effect of its prevention cow subclinical mastitis, raising milk production of cow, and milk quality is had no adverse effects.
Simultaneously, the present invention also provides a kind of preparation method who improves the Chinese herbal feed additive of milk production of cow.
In order to realize above purpose, the technical solution adopted in the present invention is:
A kind of Chinese herbal feed additive that improves milk production of cow is comprised of the raw material of following parts by weight: 15~25 parts of Radix Codonopsis, 15~25 parts of Radix Angelicae Sinensis, 25~35 parts of the fruit of glossy privets, 35~45 parts of folium isatidis, 15~25 parts of dandelions, 15~25 parts of Herba Andrographitis, 5~15 parts in Radix Glycyrrhizae.
A kind of Chinese herbal feed additive that improves milk production of cow, preferred, formed by the raw material of following parts by weight: 20 parts of Radix Codonopsis, 20 parts of Radix Angelicae Sinensis, 30 parts of the fruit of glossy privets, 40 parts of folium isatidis, 20 parts of dandelions, 20 parts of Herba Andrographitis, 10 parts in Radix Glycyrrhizae.
The present invention adopts Radix Codonopsis, Radix Angelicae Sinensis, the fruit of glossy privet, folium isatidis, dandelion, Herba Andrographitis, Radix Glycyrrhizae 7 flavor Chinese herbal medicines, according to monarch principle compound compatibility.The effect of each bulk drug is summarized as follows:
Radix Codonopsis: nature and flavor are sweet, and are flat, return spleen, lung channel, can tonifying middle-Jiao and Qi, stomach invigorating benefit lung, cure mainly weakness of the spleen and the stomach, qi-blood deficiency etc.Modern pharmacological research proof Radix Codonopsis can significantly promote its lymphocytic conversion, strengthens the immunocompetence of body, significantly strengthens simultaneously red blood cell number and content of hemoglobin, improves body to the resistivity of destructive stimulus.
Radix Angelicae Sinensis: nature and flavor are sweet, hot, bitter, and temperature is returned liver, the heart, the spleen channel, can enrich blood and invigorate blood circulation, menstruction regulating and pain relieving relaxes bowel, cure mainly irregular menstruation, through closing dysmenorrhoea, asthenia cold abdominalgia, the all cards of the deficiency of blood, modern pharmacological research proof Radix Angelicae Sinensis can strengthen the phagocytic function of macrophage and promote the lymphocyte transformation effect, thereby strengthens the immunologic function of body, also has simultaneously anti-inflammatory and antalgic, trophism etc.
The fruit of glossy privet: nature and flavor are sweet, bitter, and liver, kidney channel are returned in cold, can tonify the liver and kidney, and clearind deficient heat cures mainly and has a dizzy spell, osteopyrexia and fever etc., and the modern pharmacological research proof fruit of glossy privet has the hematopoiesis facilitation, the effect that has simultaneously anti-inflammatory and improve body's immunity.
Folium isatidis: nature and flavor are bitter, cold, the thoughts of returning home, stomach, liver, lung channel, can be clearing heat and detoxicating, cool blood, hemostasis cures mainly the high hot polydipsia of warm heat disease etc., modern pharmacological research proof folium isatidis has the effect of resisting pathogenic microbes, and staphylococcus aureus, alpha streptococcus, typhoid bacillus, Escherichia coli and shigella dysenteriae are had certain inhibitory action.
Dandelion: nature and flavor are bitter, sweet, cold, return liver, stomach warp, can be clearing heat and detoxicating, the carbuncle that disappears dissipating bind, cure mainly acute mastitis, lung carbuncle, acute appendicitis, cold, fever etc., modern pharmacological research proof dandelion has stronger bactericidal action to staphylococcus aureus resistance bacterial strain, hemolytic streptococcus, and Diplococcus pneumopniae, Pseudomonas aeruginosa, shigella dysenteriae and typhoid bacillus are also had certain bactericidal action, can strengthen the immunity function of body simultaneously.
Herba Andrographitis: nature and flavor are bitter, and are cold, the thoughts of returning home, lung, large intestine, urinary bladder channel, can be clearing heat and detoxicating, cool blood, detumescence, purging intense heat, eliminating dampness cures mainly anemopyretic cold, warm disease heating etc., that modern pharmacological research proof Herba Andrographitis has is analgesic, anti-inflammatory, D-dimer and anti-thrombus function, can improve PBL and engulf the ability of staphylococcus aureus, suppress in addition simultaneously colibacillary effect, can strengthen the immunity function of body.
Radix Glycyrrhizae: nature and flavor are sweet, and are flat, return spleen, stomach, the heart, lung channel; can invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing; relieving spasm to stop pain, coordinating the drug actions of a prescription cures mainly weakness of the spleen and the stomach; the burnout food is few; palpitaition, hysteria etc., the effects such as that modern pharmacological research proof Radix Glycyrrhizae has is antimicrobial, anti-inflammatory, antitumor, anti-sudden change, kobadrin; to cardiovascular and digestive system tool protection effect, can strengthen the immunocompetence of body simultaneously.
The present invention is clearing heat and detoxicating with above-mentioned tool according to the tcm theory basis, 7 flavor drug matching prescriptions of the carbuncle that disappears dissipating bind, nourishing qi and blood, the lactogenesis of stimulating the menstrual flow effect, prescription share the effect that has anti-inflammation, strengthens human body immune function, can effectively prevent cow subclinical mastitis disease, significantly improve milk crop, and dairy food quality is had no adverse effects.The present invention adopts pure Chinese medicinal preparation, edible safety, and side effect is little, and prescription is simple, economical and practical, is suitable for suitability for industrialized production and uses and promote.Simultaneously, also be conducive to standardization and the quality control that milk cow is used Chinese herbal feed additive.
A kind of Chinese herbal feed additive that improves milk production of cow can be prepared into other common formulations such as powder, decoction or preserved material.The present invention specifically provides a kind of preparation method of powder.
A kind of preparation method who improves the Chinese herbal feed additive of milk production of cow comprises the steps:
(1) accurately takes by weighing the bulk drug of respectively distinguishing the flavor of, removal of impurities according to parts by weight;
(2) each bulk drug of step (1) is pulverized, sieved, mix and get final product.
The present invention is prepared into powder with Chinese herbal feed additive, and method is simple, easily control, and be convenient to add.
The specific embodiment
Following embodiment only is described in further detail the present invention, but does not consist of any limitation of the invention.
Embodiment 1
Chinese herbal feed additive in the present embodiment is comprised of the raw material of following parts by weight: 15 parts of Radix Codonopsis, 15 parts of Radix Angelicae Sinensis, 25 parts of the fruit of glossy privets, 35 parts of folium isatidis, 15 parts of dandelions, 15 parts of Herba Andrographitis, 5 parts in Radix Glycyrrhizae.Concrete preparation method is: accurately take by weighing the bulk drug of respectively distinguishing the flavor of, remove wherein impurity through screening, pulverize with medicinal herb grinder, cross 60 mesh sieves and get final product.
Embodiment 2
Chinese herbal feed additive in the present embodiment is comprised of the raw material of following parts by weight: 22 parts of Radix Codonopsis, 22 parts of Radix Angelicae Sinensis, 32 parts of the fruit of glossy privets, 38 parts of folium isatidis, 18 parts of dandelions, 18 parts of Herba Andrographitis, 10 parts in Radix Glycyrrhizae.Concrete preparation method is: accurately take by weighing the bulk drug of respectively distinguishing the flavor of, remove wherein impurity through screening, pulverize with medicinal herb grinder, cross 80 mesh sieves and get final product.
Embodiment 3
Chinese herbal feed additive in the present embodiment is comprised of the raw material of following parts by weight: 20 parts of Radix Codonopsis, 20 parts of Radix Angelicae Sinensis, 30 parts of the fruit of glossy privets, 40 parts of folium isatidis, 20 parts of dandelions, 20 parts of Herba Andrographitis, 10 parts in Radix Glycyrrhizae.Concrete preparation method is: accurately take by weighing the bulk drug of respectively distinguishing the flavor of, remove wherein impurity through screening, pulverize with medicinal herb grinder, cross 100 mesh sieves and get final product.
Embodiment 4
Chinese herbal feed additive in the present embodiment is comprised of the raw material of following parts by weight: 18 parts of Radix Codonopsis, 18 parts of Radix Angelicae Sinensis, 28 parts of the fruit of glossy privets, 42 parts of folium isatidis, 22 parts of dandelions, 22 parts of Herba Andrographitis, 10 parts in Radix Glycyrrhizae.Concrete preparation method is: accurately take by weighing the bulk drug of respectively distinguishing the flavor of, remove wherein impurity through screening, pulverize with medicinal herb grinder, cross 60 mesh sieves and get final product.
Embodiment 5
Chinese herbal feed additive in the present embodiment is comprised of the raw material of following parts by weight: 25 parts of Radix Codonopsis, 25 parts of Radix Angelicae Sinensis, 35 parts of the fruit of glossy privets, 45 parts of folium isatidis, 25 parts of dandelions, 25 parts of Herba Andrographitis, 15 parts in Radix Glycyrrhizae.Concrete preparation method is: accurately take by weighing the bulk drug of respectively distinguishing the flavor of, remove wherein impurity through screening, pulverize with medicinal herb grinder, cross 80 mesh sieves and get final product.
More than the preferred using method of each embodiment be: Chinese herbal feed additive is added in the daily ration of lactation milk cow in mid-term, concentrate spice, the 150g that feeds every day is used in conjunction 15 days.
Chinese herbal feed additive improves the test report of milk production of cow
Materials and methods
Experimental animal: be selected from 80 of the holstein cows of Ju Er cattle farm, Luoyang City, body weight is about 550kg, and 2~4 parity are in lactation mid-term, do not have significant difference (P>0.05) between the lactation amount of 80 cow heads.
Test group 1,2,3: the corresponding Chinese herbal feed additive that adds embodiment 1,2,3 preparations, consumption is 150g/ day, feeds continuously 15 days;
Control group: the basal diet of only feeding, do not add any feed addictive.
Test method: test group and control group are given in 80 tested milk cow Random assignments, every group 20, milk twice every day, the time is respectively early 6:00 and late 6:00, before experimental period, the accurate weighing of 15d, 30d records the output of milk of every group of every cow head every day, the results are shown in Table 1.
Each processed group of table 1 is on the impact of milk production of cow
Figure BDA00002228653200051
Annotate: mark without same letter person's significant difference with the column data shoulder.
The SPSS statistical analysis shows that the output of milk of test group 1,2,3 15d, 30d is significantly higher than control group, and wherein, the output of milk of test group 3 is the highest.From the above, the Chinese herbal feed additive of the present invention's preparation can significantly improve milk production of cow, and wherein, each raw material proportioning of the Chinese medicine among the embodiment 3 is best.
Table 2 Chinese herbal feed additive improves the Economic and Efficiency Analysis of the output of milk
Figure BDA00002228653200052
As shown in Table 2, the every cow head of test group fecund every day milk 3.12kg, according to 3.3 yuan/kg of the purchasing price calculating of current raw material milk, every cow head is on average increased income 8.5 yuan, remarkable in economical benefits every day.
Chinese herbal feed additive is on the impact of milk Milk Quality
Materials and methods
Experimental animal: be selected from 80 of the holstein cows of Ju Er cattle farm, Luoyang City, body weight is about 500kg, and 2~4 parity are in lactation mid-term, do not have significant difference (P>0.05) between the lactation amount of 80 cow heads.
Test group 1,2,3: the corresponding Chinese herbal feed additive that adds embodiment 2,3,4 preparations, consumption is 150g/ day, feeds continuously 15 days;
Control group: the basal diet of only feeding, do not add any feed addictive.
Test method: test group and control group are given in 80 tested milk cow Random assignments, 20 every group, before test, 15d, 30d gather respectively newborn sample.Gather after milking in the morning, before filtering, stir squeezing good milk, then from milk churn, extract 100mL fresh milk with syringe and inject the Special sample bottle, every corresponding syringe of ox, avoid cross-reference, measure each physical index of milk with the analysis of milk composition instrument that FOSS company produces, the results are shown in Table 3.
Each processed group of table 3 is on the impact of milk constituents
Figure BDA00002228653200061
The SPSS statistical analysis shows, between butterfat percnetage, lactoprotein and the lactose content of test group 1,2,3 15d, 30d and the control group without significant difference.Show that the Chinese herbal feed additive that the present invention prepares has no adverse effects to milk quality.
The report of Chinese herbal feed additive prevention cow subclinical mastitis disease
Experimental animal:
Be selected from 40 of the holstein cows of Ju Er cattle farm, Luoyang City, body weight is about 500kg, and 2~4 parity are in lactation mid-term, do not have significant difference (P>0.05) between the lactation amount of 40 cow heads.
Test group 1,2,3: the corresponding Chinese herbal feed additive that adds embodiment 3,4,5 preparations, consumption is 150g/ day, feeds continuously 15 days;
Control group: the basal diet of only feeding, do not add any feed addictive.
Test method: test group and control group are given in 40 tested milk cow Random assignments, before test, gather respectively newborn sample after the off-test.After milking in the morning, the fresh milk of getting about 100mL injects ready sample bottle, carries out mark, and measuring the used method of mammitis is alkyl sulfate curdled milk test method(s) (CMT), the results are shown in Table 4.
The criterion of CMT testing result: milk is unchanged, grumeleuse do not occur, and is negative, and decision symbol is "-"; Milk has microprecipitation, but namely disappears soon, and for suspicious, decision symbol is " ± "; The fractal gel in milk middle part is the weak positive "+"; All form gels, grumeleuse stopped to stir then that the grumeleuse concave-convex surface is attached at the bottom of the ware when revolution was stirred in centralized, and positive, decision symbol is " ++ "; All be gel, grumeleuse stopped to stir then and restores to the original state in centralized when revolution was stirred, and was attached at the bottom of the ware, was strong positive, and decision symbol is " +++".
Each processed group of table 4 is on the impact of cow subclinical mastitis disease
Figure BDA00002228653200071
Annotate: adding 1-before the test ox numbering in the form is test group 1, and 2-is test group 2, and 3-is test group 3, and all the other are control group.
As shown in Table 4, the incidence of the cow subclinical mastitis disease of test pre-stage test group and control group is 70%, the incidence of later stage test group is reduced to 30%, and control group is increased to 80%, shows that the Chinese herbal feed additive that the present invention prepares has obvious prevention effect to cow subclinical mastitis disease.

Claims (3)

1. a Chinese herbal feed additive that improves milk production of cow is characterized in that, is comprised of the raw material of following parts by weight: 15~25 parts of Radix Codonopsis, 15~25 parts of Radix Angelicae Sinensis, 25~35 parts of the fruit of glossy privets, 35~45 parts of folium isatidis, 15~25 parts of dandelions, 15~25 parts of Herba Andrographitis, 5~15 parts in Radix Glycyrrhizae.
2. Chinese herbal feed additive according to claim 1 is characterized in that, is comprised of the raw material of following parts by weight: 20 parts of Radix Codonopsis, 20 parts of Radix Angelicae Sinensis, 30 parts of the fruit of glossy privets, 40 parts of folium isatidis, 20 parts of dandelions, 20 parts of Herba Andrographitis, 10 parts in Radix Glycyrrhizae.
3. the preparation method of the Chinese herbal feed additive of a raising milk production of cow as claimed in claim 1 or 2 is characterized in that, comprises the steps:
(1) accurately takes by weighing the bulk drug of respectively distinguishing the flavor of, removal of impurities according to parts by weight;
(2) each bulk drug of step (1) is pulverized, sieved, mix and get final product.
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CN104068221A (en) * 2014-07-10 2014-10-01 南宁荣港生物科技有限公司 Traditional Chinese medicine additive capable of improving lactation yield of diary cow and preparation method thereof
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