CN104524504A - Traditional Chinese medicine for treating female idiopathic edema - Google Patents

Traditional Chinese medicine for treating female idiopathic edema Download PDF

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Publication number
CN104524504A
CN104524504A CN201410796771.6A CN201410796771A CN104524504A CN 104524504 A CN104524504 A CN 104524504A CN 201410796771 A CN201410796771 A CN 201410796771A CN 104524504 A CN104524504 A CN 104524504A
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China
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traditional chinese
chinese medicine
edema
idiopathic edema
treating
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CN201410796771.6A
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Chinese (zh)
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CN104524504B (en
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许丹
董宇翔
杨雪芹
何滨
高霞
李有田
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Jilin University
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Jilin University
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Abstract

The invention discloses a traditional Chinese medicine for treating female idiopathic edema, belongs to the field of traditional Chinese medicines and aims at providing the traditional Chinese medicine for treating the female idiopathic edema with adoption of the traditional Chinese medicine theory and capabilities of warming yang, benefiting qi, excreting dampness, promoting urination and reducing swelling. The traditional Chinese medicine is prepared from the following medicinal raw materials including cassia twigs, dried tangerine peels, areca peels, polyporus, poria cocos, rhizoma alismatis, atractylodes, fresh ginger peels, radix bupleuri, snakegourd fruits, all-grasses of desertliving cistanche and 5-10 of twotooth achyranthes root. The traditional Chinese medicine is simple in preparation, low in cost, good in curative effect and good in social and economical benefits, does not have side or toxic effect and is mainly used for treating the female idiopathic edema.

Description

The Chinese medicine for the treatment of women idiopathic edema
Technical field
The invention belongs to the field of Chinese medicines.
Background technology
Women's idiopathic edema is common clinical, frequently-occurring disease, and a kind of especially agnogenic water and salt metabolic disturbance and to cause some position of body to occur take edema as a class syndrome of cardinal symptom.Show as puffiness of face, edema of pair of lower extremities or anasarca, all get rid of heart source property edema through the every inspection of doctor trained in Western medicine, liver source property edema, pulmonary edema, edema caused by the sufferer such as endocrine such as property edema and hypothyroidism etc. of kidney source.
Summary of the invention
The object of the invention is to adopt theory of Chinese medical science, with warming YANG activating QI, the treatment by Chinese herbs women idiopathic edema of the little clock of eliminating dampness and diuresis.
Important part of raw material that the present invention makes effective ingredient consists of:
Ramulus Cinnamomi 5-10 Pericarpium Citri Reticulatae 10-15 Pericarpium Arecae 5-15 Polyporus 10-20
Poria 10-15 Rhizoma Alismatis 10-15 Rhizoma Atractylodis Macrocephalae 10-15 CORTEX ZINGIBERIS RHIZOMAE 5-10
Radix Bupleuri 10-15 Fructus Trichosanthis 15-20 Herba Cistanches 10-15 Radix Achyranthis Bidentatae 5-10.
The present invention prepares simply, cheap, and good effect, has no side effect, social and good in economic efficiency.The present invention is mainly used in treatment women idiopathic edema.
Detailed description of the invention
Important part of raw material that the present invention makes effective ingredient consists of:
Ramulus Cinnamomi 5-10 Pericarpium Citri Reticulatae 10-15 Pericarpium Arecae 5-15 Polyporus 10-20
Poria 10-15 Rhizoma Alismatis 10-15 Rhizoma Atractylodis Macrocephalae 10-15 CORTEX ZINGIBERIS RHIZOMAE 5-10
Radix Bupleuri 10-15 Fructus Trichosanthis 15-20 Herba Cistanches 10-15 Radix Achyranthis Bidentatae 5-10.
preparation method is:
By above 12 taste Chinese medicines, add 8 times amount water soaking and decoct secondary, each 0.5 hour in 30 minutes, filter, at merging filtrate, be concentrated into 1000ml(m1), add sodium benzoate 2g, make it dissolve, then cold preservation 12 hours, filter, filtrate adding distil water is adjusted to 1000ml, stirs evenly, subpackage and get final product.
Embodiment 1
Important part of raw material that the present invention makes effective ingredient consists of:
Ramulus Cinnamomi 5 Pericarpium Citri Reticulatae 10 Pericarpium Arecae 5 Polyporus 10
Poria 10 Rhizoma Alismatis 10 Rhizoma Atractylodis Macrocephalae 10 CORTEX ZINGIBERIS RHIZOMAE 5
Radix Bupleuri 10 Fructus Trichosanthis 15 Herba Cistanches 10 Radix Achyranthis Bidentatae 5;
Preparation method is the same.
Embodiment 2:
Important part of raw material that the present invention makes effective ingredient consists of:
Ramulus Cinnamomi 7.5 Pericarpium Citri Reticulatae 12.5 Pericarpium Arecae 10 Polyporus 15
Poria 12.5 Rhizoma Alismatis 12.5 Rhizoma Atractylodis Macrocephalae 12.5 CORTEX ZINGIBERIS RHIZOMAE 7.5
Radix Bupleuri 12.5 Fructus Trichosanthis 17.5 Herba Cistanches 12.5 Radix Achyranthis Bidentatae 7.5;
Preparation method is the same.
Embodiment 3:
Important part of raw material that the present invention makes effective ingredient consists of:
Ramulus Cinnamomi 10 Pericarpium Citri Reticulatae 15 Pericarpium Arecae 15 Polyporus 20
Poria 15 Rhizoma Alismatis 15 Rhizoma Atractylodis Macrocephalae 15 CORTEX ZINGIBERIS RHIZOMAE 10
Radix Bupleuri 15 Fructus Trichosanthis 20 Herba Cistanches 15 Radix Achyranthis Bidentatae 10;
Preparation method is the same.
Embodiment 4:
The optimum feed stock weight portion that the present invention makes effective ingredient consists of:
Ramulus Cinnamomi 10 Pericarpium Citri Reticulatae 15 Pericarpium Arecae 15 Polyporus 20
Poria 15 Rhizoma Alismatis 1 Rhizoma Atractylodis Macrocephalae 15 CORTEX ZINGIBERIS RHIZOMAE 10
Radix Bupleuri 15 Fructus Trichosanthis 20 Herba Cistanches 15 Radix Achyranthis Bidentatae 10;
Preparation method is the same.
character:
This product is brown liquid, and have clear jolting in a small amount, dispersible precipitation, feeble QI is fragrant, and bitter in the mouth is pungent.
differentiate:
Get this product 20ml and add formic acid 80ml, stir evenly, leave standstill 30 minutes, filter, filtrate evaporate to dryness, the residue 10ml that adds water makes it to dissolve, with chloroform extraction 3 times, each 20ml, discard chloroform solution, water layer again with water saturation, n-butanol extraction 3 times, each 20ml, merge n-butyl alcohol liquid, wash 2 times with n-butyl alcohol saturation water, each 25ml, after emulsifying, centrifugal in 4000 revs/min, divide and get n-butyl alcohol liquid, evaporate to dryness, residue adds methanol 1m makes dissolving, as need testing solution.Another extracting liquorice control medicinal material 1g, filters, filtrate evaporate to dryness.Every regulation that identification result is relevant under meeting mixture item.(Chinese Pharmacopoeia version in 2000 annex 1, j).
usage of the present invention and consumption:
Oral, a 100ml, 2 times on the one, temperatureization taking medicine after meal.
Untoward reaction: pole few patients occasionally has times of defecation to increase.
taboo and points for attention:
1. clothes are avoided to this Chinese medicine allergy sufferers;
When 2. catching a cold, carefully to take;
3., when green grass or young crops, female middle-aged physiology phase, clothes are avoided;
4. Aqua Folium Camelliae sinensis and congee with mung beans is avoided;
The merit that monarch drug of the present invention is Ramulus Cinnamomi, Herba Cistanches plays warming YANG activating QI, inducing diuresis to remove edema.Ministerial drug Radix Bupleuri, Fructus Trichosanthis, Pericarpium Citri Reticulatae with depressed liver-energy dispersing and QI regulating, the folding of regulating fluid apssage.Adjuvant drug is the effect that Poria, Polyporus, Rhizoma Alismatis, Pericarpium Arecae etc. play spleen invigorating, eliminating dampness and diuresis, and make medicine be Radix Achyranthis Bidentatae, priming is descending, transports to bladder under water is wet, forms urine and excretes.All medicines are public, gather warming YANG activating QI altogether, invigorating the spleen for eliminating dampness, eliminating dampness and diuresis, edema extinction.Therefore medicine card conforms to, treating both the principal and secondary aspects of a disease, brings out the best in each other.
The present invention the observation of curative effect for the treatment of women idiopathic edema:
object:observe a kind of Chinese Herbs for the treatment of women's idiopathic edema. method:adopt random packet: treatment group 41 example, take traditional Chinese medicine treatment.Matched group 40 example, takes Western medicine (hydrochlorothiazide) treatment.Two groups are 2 weeks is a course for the treatment of, then observes hydrosarca and disappears and experimental check change. result:treatment group 41, cures 27 examples (65.9%), invalid 5 examples (12.2%) of 9 examples that take a turn for the better (21.9%), and total effective rate 87.8%.. follows up a case by regular visits to (3 months) recurrence example 3 example (7.3%); Matched group 40 example, cures 13 examples (32.5%) and to take a turn for the better invalid 15 examples (37.5%) of 19 examples (30.0%); Total effective rate: 62.5%, recurrence example 29 example (70.0%). conclusion:treatment by Chinese herbs women idiopathic edema is effective, reliable and curative effect persistent, and relapse rate is low, has no adverse reaction.And matched group (Western medicine), although effectively, be temporary transient, take Western medicine with regard to diuresis, the just recurrence of drug withdrawal edema, few patients on the contrary edema increases the weight of, and has untoward reaction, as: feel sick, tell, diarrhoea, malaise, blood pressure drops, the symptoms such as dizziness, relapse rate is high especially.
1 clinical data
41 examples are the female patient of out-patient based on edema, minimum 35 years old of age, maximum 69 years old, average 43.8 years old, course of disease 2-9, all looked into the routine examinations such as cardiac function, renal function, liver function, pulmonary function, all except the case of unfaithful intention source property, liver source property, kidney source property, pulmonary and Hypothyroidism and nutritional edema is treatment object of statistics.
2 Therapeutic Method
Treatment group is taken and from intending prescriptions of Chinese medicine is: Ramulus Cinnamomi 10g, Pericarpium Citri Reticulatae 15g, Pericarpium Arecae 15g, Polyporus 15g, Poria 15g, Rhizoma Alismatis 10g, Rhizoma Atractylodis Macrocephalae 15g, CORTEX ZINGIBERIS RHIZOMAE 10g, Radix Bupleuri 15g, Fructus Trichosanthis 20g, meat Poria 15g, Radix Achyranthis Bidentatae 10g.Be decocted in water for oral dose, 2 times on the one, each 100ml, serve on 2 weeks; The oral hydrochlorothiazide 25mg of matched group, 2 times on the one, serve on 2 weeks.
3 criterions of therapeutical effect
Cure: drug withdrawal is after one month, and edema disappears completely, without recidivist; Take a turn for the better, drug withdrawal is after one month, and edema obviously goes down, but sees Mild edema person; Invalid: without obvious changer before and after treatment.
4 therapeutic outcomes:
Treatment group 41 example, cures 27 examples (65.9%); 9 examples that take a turn for the better (21.9%); Invalid 5 examples (12.2%) total effective rate is 87.8%.Follow up a case by regular visits to (2 months), this group patients with recurrent 3 example (7.3%); Team leader organizes 40 examples, cures 13, example (32.5%), 12 examples that take a turn for the better (30.0%), invalid 15 examples (37.5%).Total effective rate (62.5%), this group patients with recurrent 28 example (70.0%) in a word:treatment by Chinese herbs women idiopathic edema is effective, reliable and curative effect persistent, and relapse rate is low, has no adverse reaction.And matched group (Western medicine), although effectively, be temporary transient, take Western medicine with regard to diuresis, the just recurrence of drug withdrawal edema, few patients on the contrary edema increases the weight of, and has untoward reaction, as: feel sick, tell, diarrhoea, malaise, blood pressure drops, the symptoms such as dizziness, relapse rate is high especially.
5 discuss
Women's idiopathic edema is common clinical, frequently-occurring disease, and a kind of especially agnogenic water and salt metabolic disturbance and to cause some position of body to occur take edema as a class syndrome of cardinal symptom.Show as puffiness of face, edema of pair of lower extremities or anasarca, all get rid of heart source property edema through the every inspection of doctor trained in Western medicine, liver source property edema, pulmonary edema, edema caused by the sufferer such as endocrine such as property edema and hypothyroidism etc. of kidney source.
Primary disease belongs to " edema ", " edema due to wind pathogen " category of Chinese medicine, married woman take blood as this, the warp, band, tire, product etc. of middle aged and aged women Yin Shengli aspect are many because of easy damaged deficiency of YIN-blood, with the passing of time cause damage of kidney-YIN, due to deficiency of kidney-QI, kidney yang is lost, kidney essense cannot change raw kidney qi, cause the gasification of kidney not normal, folding is unfavorable, causes water liquid dysbolismus and edema occurs; Again due to the easy excessive anger impairing the liver of women, cause the catharsis function of liver to neglect one's duty, forming the metabolism of water liquid not normal, there is further edema in retention of water-damp in the body.Therefore treatment should adopt warming YANG activating QI, liver-smoothing, qi-regulating, eliminating dampness and diuresis detumescence Chinese medicine, side in monarch drug Ramulus Cinnamomi, Herba Cistanches with the kidney invigorating, warming YANG activating QI, diuretic.Ministerial drug Radix Bupleuri, Fructus Trichosanthis, Pericarpium Citri Reticulatae with depressed liver-energy dispersing and QI regulating, the folding of regulating fluid apssage.Adjuvant drug: Polyporus, Poria, the medicine eliminating dampness and diuresises such as Rhizoma Alismatis, help with Rhizoma Atractylodis Macrocephalae spleen invigorating victory wet.Make medicine, Radix Achyranthis Bidentatae, priming is descending, transports to bladder, excrete under making water wet.All medicines share, and gather warming YANG activating QI altogether, liver-smoothing, qi-regulating, the merit of eliminating dampness and diuresis detumescence.

Claims (1)

1. treat a Chinese medicine for women's idiopathic edema, it is characterized in that: the important part of raw material of making effective ingredient consists of:
Ramulus Cinnamomi 5-10 Pericarpium Citri Reticulatae 10-15 Pericarpium Arecae 5-15 Polyporus 10-20
Poria 10-15 Rhizoma Alismatis 10-15 Rhizoma Atractylodis Macrocephalae 10-15 CORTEX ZINGIBERIS RHIZOMAE 5-10
Radix Bupleuri 10-15 Fructus Trichosanthis 15-20 Herba Cistanches 10-15 Radix Achyranthis Bidentatae 5-10.
CN201410796771.6A 2014-12-22 2014-12-22 Treat the Chinese medicine of women idiopathic edema Expired - Fee Related CN104524504B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101066444A (en) * 2007-06-05 2007-11-07 北京艺信堂医药研究所 Chinese medicine prepn for treating acute nephritis
CN101703639A (en) * 2009-11-10 2010-05-12 陈卫 Damp-clearing and heat calming pill

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101066444A (en) * 2007-06-05 2007-11-07 北京艺信堂医药研究所 Chinese medicine prepn for treating acute nephritis
CN101703639A (en) * 2009-11-10 2010-05-12 陈卫 Damp-clearing and heat calming pill

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张秋雨等: "《方剂学》", 31 August 2005, 第四军医大学出版社 *
李传岐: "五苓散加味治疗特发性水肿", 《山西中医》 *

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