CN101301347B - Chinese medicine for treating impotence and preparation - Google Patents
Chinese medicine for treating impotence and preparation Download PDFInfo
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- CN101301347B CN101301347B CN2008100164379A CN200810016437A CN101301347B CN 101301347 B CN101301347 B CN 101301347B CN 2008100164379 A CN2008100164379 A CN 2008100164379A CN 200810016437 A CN200810016437 A CN 200810016437A CN 101301347 B CN101301347 B CN 101301347B
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Abstract
The invention belongs to the traditional Chinese medicine field, and in particular relates to a traditional Chinese medicine for treating impotence and a method for making the same. The traditional Chinese medicine is mainly made by processing and refining velvet antler, epimedium herb, twotooth achyranthes root, ginseng, astragalus root, angelica and lyophilized royal jelly. The medicines in compatibility bring out the best in each other, jointly guarantee the efficacy of warming Yang and nourishing kidney, and play a significant role in warming kidney and strengthening Yang. Moreover, the traditional Chinese medicine has the advantages of good clinical efficacy, fast effect, short treatment course, no obvious toxic and side effect, etc., which is a good medicine for treating impotence.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate in particular to a kind of Chinese medicine and preparation method for the treatment of sexual impotence.
Background technology
The Chinese medicine sexual impotence: the traditional Chinese medical science is with the weak erectile problem of penis or act and not hard, so that influences the sexual impotence of sexual life meaning.The cardinal symptom of primary disease is not play, face room erectile problem or act a little less than penis withers and not hard, and sexual behaviour incapability, normal sex-linkage are desired to fall sharply, even do not have libido, and lassitude or palpitation and being susceptible to fright, depressed joyless, the timid smooth symptom of mind such as suspicious.Chinese medical theory is thought " people is kidney at all; the power of property is essence ", to fundamentally treat to belong to and suffer from a deficiency of the kidney or/and the sexual impotence of syndrome of deficiency of kidney-YANG (erection disturbance or ED), premature ejaculation must both be mended the congenital foundation, mend the life of the day after tomorrow again, " kidney tonifying and controlling nocturnal emission with astringent drugs " could allow the man have real property good fortune.Western modern medicine treatment sexual impotence: sexual impotence is meant the male penis erection dysfunction, and showing as the male is having under the situation of libido, and the penis anorthosis maybe can erect but be not hard, can not have sexual intercourse activity and dyspareunia takes place.The reason that causes sexual impotence is a lot, and except that minority is that great majority were psychological and constitutive the organic disease of reproductive system caused, sexual impotence appears in the man more than 50 years old, and majority is that physiological degeneration changes.The common method of western modern medicine treatment sexual impotence all belongs to takes stopgap measures, and is used for etiology unknown or at etiological treatment and the person of not proving effective does not still have the radical cure medicine of being satisfied with at present, majority can only reach short term effect, can not effect a radical cure more.
Summary of the invention
The present invention has overcome the deficiencies in the prior art, and a kind of Chinese medicine for the treatment of sexual impotence and preparation method thereof is provided.The present invention treats the Chinese medicine of sexual impotence, be prepared from by following component, all in weight portion: 4.1～7.2 parts in Cornu Cervi Pantotrichum, 16.4～28.8 parts of Herba Epimedii, 9.0～15.8 parts of Radix Achyranthis Bidentataes, 8.2～14.4 parts of Radix Ginsengs, 16.4～28.8 parts of the Radixs Astragali, 16.4～28.8 parts of Radix Angelicae Sinensis, 0.6～1.5 part of Lac regis apis lyophilized powder.
The present invention treats the Chinese medicine of sexual impotence, is prepared from by following component, all in weight portion: 4.5 parts in Cornu Cervi Pantotrichum, 16.8 parts of Herba Epimedii, 9.5 parts of Radix Achyranthis Bidentataes, 14.0 parts of Radix Ginsengs, 28.0 parts of the Radixs Astragali, 22.0 parts of Radix Angelicae Sinensis, 0.6 part of Lac regis apis lyophilized powder.
The present invention treats the Chinese medicine of sexual impotence, is prepared from by following component, all in weight portion: 4.5 parts in Cornu Cervi Pantotrichum, 16.8 parts of Herba Epimedii, 11.0 parts of Radix Achyranthis Bidentataes, 13.0 parts of Radix Ginsengs, 27.0 parts of the Radixs Astragali, 20.0 parts of Radix Angelicae Sinensis, 0.6 part of Lac regis apis lyophilized powder.
The present invention treats the Chinese medicine of sexual impotence, is prepared from by following component, all in weight portion: 4.5 parts in Cornu Cervi Pantotrichum, 16.8 parts of Herba Epimedii, 12.0 parts of Radix Achyranthis Bidentataes, 13.0 parts of Radix Ginsengs, 26.0 parts of the Radixs Astragali, 18.0 parts of Radix Angelicae Sinensis, 0.6 part of Lac regis apis lyophilized powder.
Chinese medicine of the present invention is mainly formed by Cornu Cervi Pantotrichum, Herba Epimedii, Radix Achyranthis Bidentatae, Radix Ginseng, the Radix Astragali, Radix Angelicae Sinensis, Lac regis apis lyophilized powder processing and refining, and its dosage form comprises capsule, tablet and granule.Prescription is separated: Cornu Cervi Pantotrichum kidney-replenishing, benefiting essence-blood, strong waist knee joint are monarch drug; But Herba Epimedii kidney-replenishing, bone and muscle strengthening, principal drug assistance warming YANG kidney tonifying, Radix Achyranthis Bidentatae liver and kidney tonifying, strong waist knee joint, Lac regis apis lyophilized powder strengthening by means of tonics, the liver benefiting spleen invigorating, more than 3 the flavor Chinese medicines be ministerial drug altogether; Radix Ginseng, the Radix Astragali, Radix Angelicae Sinensis spleen benefiting and replenishing qi and blood are mended the day after tomorrow (taste) to support congenital (kidney), have the meaning of the first QI invigorating of supporing yang palpus again, so be adjuvant drug altogether; The Radix Achyranthis Bidentatae priming is descending goes into the usefulness that the kidney the common reed is made messenger drug.More than all medicine compatibilities, bring out the best in each other, gather the effect of warming YANG kidney tonifying altogether, Chinese medicine cures mainly suffers from a deficiency of the kidney or/and the syndrome of deficiency of kidney-YANG sexual impotence, disease is seen sexual impotence erectile problem, soreness of the waist and knees, hyposexuality, aversion to cold and cold limbs, lethargy etc.; Western medicine is applicable to diseases such as sexual impotence (erection disturbance or ED), premature ejaculation, seminal emission, hyposexuality, forgetful insomnia, spiritlessness and weakness, waist soreness, waist abdomen cold type of pain, frequent micturition.
The Chinese medicine of treatment sexual impotence of the present invention, its preparation method is as follows:
(1) get the Cornu Cervi Pantotrichum dry sterilization, be ground into fine powder by ingredients weight parts, sieve, standby;
(2) get the ginseng crude drug by ingredients weight parts and decoct with water extraction three times separately, the decocting that adds for the first time 4～7 times of amounts of Radix Ginseng weight boiled 2 hours, adding for the second time 3～6 times of water gagings of Radix Ginseng weight decocted 1.5 hours, adding 2～4 times of water gagings of Radix Ginseng weight for the third time decocted 1.0 hours, collecting decoction filters or/and leave standstill;
(3) getting Herba Epimedii, Radix Achyranthis Bidentatae, the Radix Astragali, Radix Angelicae Sinensis by ingredients weight parts decocts with water and extracts three times, the decocting that adds for the first time 4～7 times of amounts of whole extraction medical material weight boiled 2 hours, adding for the second time 3～6 times of water gagings of whole extraction medical material weight decocted 1.5 hours, adding 2～4 times of water gagings of whole extraction medical material weight for the third time decocted 1.0 hours, collecting decoction filters or/and leave standstill;
(4) get the filtrate of above-mentioned (2) and (3) or/and supernatant is condensed into thick paste, drying is ground into fine powder, sieves;
(5) add above-mentioned velvet powder and, add or do not add pharmaceutic adjuvant, granulate or do not granulate, be packed into capsule and promptly get capsule by the Lac regis apis lyophilized powder mixing of ingredients weight parts; Or add pharmaceutic adjuvant an amount of granulate or do not granulate make sheet and promptly get tablet; Or add pharmaceutic adjuvant and make granule in right amount and promptly get granule.
Pharmaceutic adjuvant is generally: starch, dextrin, lactose, microcrystalline Cellulose, sucrose, stearic acid, magnesium stearate etc., its kind and consumption are the amount doesn't matter according to preparation purpose and dosage form arts demand.
Pharmacodynamic study
Adopt single at random blind method to carry out clinical observation on the therapeutic effect to treatment by Chinese herbs sexual impotence of the present invention.Clinical data: treatment by Chinese herbs group 102 examples of the present invention, the oldest person 57 years old, reckling 26 years old, 46.1 years old mean age, the elder of the course of disease 3 years, the shortest person 1 month, average course of disease 4.2 months.Observational technique: adopt open trial to observe, disease situation of change before and after the record patient medication is carried out the rank scores statistics, carries out clinical observation and record weekly once, and all do routine blood test and hepatic and renal function inspection, the untoward reaction that observation may occur in the treatment front and back; 4 weeks were a course of treatment, added up curative effect after observing two courses of treatment continuously.Therapeutic outcome: treatment by Chinese herbs group 102 examples of the present invention, clinical recovery 52 examples, produce effects 29 examples, effective 12 examples, clinical recovery rate 51.98%, obvious effective rate 27.43%, effective percentage 11.76%, total effective rate are 91.18%.Conclusion: Chinese medicine of the present invention has remarkable therapeutical effect to sexual impotence (curing mainly syndrome of deficiency of kidney-YANG), and treatment by Chinese herbs group clinical efficacy of the present invention is better than oral YISHEN XINGYANG JIAONANG matched group.Untoward reaction: do not observe serious adverse reaction, the dry xerostomia of accidental lip, happiness drink, constipation with dry stool, the scorching sense of whole body, routine blood test and the no abnormal change of hepatic and renal function illustrate that Chinese medicine of the present invention is safe and reliable before and after all patient treatments, untoward reaction is very little.
The invention has the beneficial effects as follows: it is mainly formed by Cornu Cervi Pantotrichum, Herba Epimedii, Radix Achyranthis Bidentatae, Radix Ginseng, the Radix Astragali, Radix Angelicae Sinensis, Lac regis apis lyophilized powder seven flavor raw material of Chinese medicine processing and refinings, more than all medicine compatibilities, bring out the best in each other, gather the effect of warming YANG kidney tonifying altogether.Pharmacodynamic study is the result show, Chinese medicine of the present invention can obviously improve the castrated rats penis to the irritability of outside stimulus, shorten erection incubation period, can increase castration male rat accessory sex organ's weight coefficient, and can obviously raise rat blood serum T, F content, and the weight that can impel hypophysis, adrenal gland's weight coefficient to increase, regulate thymus, spleen, the every symptom of yang deficiency mice is eased even disappears, above result shows that Chinese medicine of the present invention has the effect of significant warming the kidney to invigorate YANG.Chinese medicine of the present invention had both been mended the congenital foundation, mend the life of the day after tomorrow again, " kidney tonifying and controlling nocturnal emission with astringent drugs ", can fundamentally treat to belong to and suffer from a deficiency of the kidney or/and the sexual impotence of syndrome of deficiency of kidney-YANG (erection disturbance or ED), premature ejaculation etc., taking the course of its own aspect the treatment by Chinese herbs sexual impotence, clinical observation on the therapeutic effect shows that further the present invention has advantages such as clinical efficacy height, instant effect, short treating period, no obvious toxic-side effects, is the good medicine of treatment sexual impotence.
The specific embodiment
Mode below by embodiment further specifies the present invention.
Embodiment 1
The Chinese medicine of treatment sexual impotence of the present invention is prepared from by following component, all in weight portion:
4.5 parts in Cornu Cervi Pantotrichum, 16.8 parts of Herba Epimedii, 9.5 parts of Radix Achyranthis Bidentataes, 14.0 parts of Radix Ginsengs, 28.0 parts of the Radixs Astragali, 22.0 parts of Radix Angelicae Sinensis, 0.6 part of Lac regis apis lyophilized powder.
Preparation method is as follows:
(1) get Cornu Cervi Pantotrichum 4.5Kg dry sterilization, be ground into fine powder, sieve, standby;
(2) get ginseng crude drug 14.0Kg and decoct with water extraction three times separately, the decocting that adds for the first time 4～7 times of amounts of Radix Ginseng weight boiled 2 hours, added 3～6 times of water gagings of Radix Ginseng weight for the second time and decocted 1.5 hours, added 2～4 times of water gagings of Radix Ginseng weight for the third time and decocted 1.0 hours, collecting decoction filters or/and leave standstill;
(3) getting Herba Epimedii 16.8Kg, Radix Achyranthis Bidentatae 9.5Kg, Radix Astragali 28.0Kg, Radix Angelicae Sinensis 22.0Kg decocts with water and extracts three times, the decocting that adds for the first time 4～7 times of amounts of whole extraction medical material weight boiled 2 hours, adding for the second time 3～6 times of water gagings of whole extraction medical material weight decocted 1.5 hours, adding 2～4 times of water gagings of whole extraction medical material weight for the third time decocted 1.0 hours, collecting decoction filters or/and leave standstill;
(4) get the filtrate of above-mentioned (2) and (3) or/and supernatant is condensed into thick paste, drying is ground into fine powder, sieves;
(5) add above-mentioned velvet powder, 0.6Kg Lac regis apis lyophilized powder, mixing can add or not add pharmaceutic adjuvant, granulates or does not granulate, and is packed into capsule and promptly gets capsule; Can add pharmaceutic adjuvant an amount of granulate or do not granulate make sheet and promptly get tablet; Or add pharmaceutic adjuvant and make granule in right amount and promptly get granule.
Embodiment 2
The Chinese medicine of treatment sexual impotence of the present invention is prepared from by following component, all in weight portion:
4.5 parts in Cornu Cervi Pantotrichum, 16.8 parts of Herba Epimedii, 11.0 parts of Radix Achyranthis Bidentataes, 13.0 parts of Radix Ginsengs, 27.0 parts of the Radixs Astragali, 20.0 parts of Radix Angelicae Sinensis, 0.6 part of Lac regis apis lyophilized powder.
Other component batching processing and preparation method are with embodiment 1.
Embodiment 3
The Chinese medicine of treatment sexual impotence of the present invention is prepared from by following component, all in weight portion:
4.5 parts in Cornu Cervi Pantotrichum, 16.8 parts of Herba Epimedii, 12.0 parts of Radix Achyranthis Bidentataes, 13.0 parts of Radix Ginsengs, 26.0 parts of the Radixs Astragali, 18.0 parts of Radix Angelicae Sinensis, 0.6 part of Lac regis apis lyophilized powder.
Other component batching processing and preparation method are with embodiment 1.
Claims (6)
1. Chinese medicine for the treatment of sexual impotence, it is characterized in that, be prepared from by following component, all in weight portion: 4.1～7.2 parts in Cornu Cervi Pantotrichum, 16.4～28.8 parts of Herba Epimedii, 9.0～15.8 parts of Radix Achyranthis Bidentataes, 8.2～14.4 parts of Radix Ginsengs, 16.4～28.8 parts of the Radixs Astragali, 16.4～28.8 parts of Radix Angelicae Sinensis, 0.6～1.5 part of Lac regis apis lyophilized powder.
2. the Chinese medicine of treatment sexual impotence as claimed in claim 1, it is characterized in that, be prepared from by following component, all in weight portion: 4.5 parts in Cornu Cervi Pantotrichum, 16.8 parts of Herba Epimedii, 9.5 parts of Radix Achyranthis Bidentataes, 14.0 parts of Radix Ginsengs, 28.0 parts of the Radixs Astragali, 22.0 parts of Radix Angelicae Sinensis, 0.6 part of Lac regis apis lyophilized powder.
3. the Chinese medicine of treatment sexual impotence as claimed in claim 1, it is characterized in that, be prepared from by following component, all in weight portion: 4.5 parts in Cornu Cervi Pantotrichum, 16.8 parts of Herba Epimedii, 11.0 parts of Radix Achyranthis Bidentataes, 13.0 parts of Radix Ginsengs, 27.0 parts of the Radixs Astragali, 20.0 parts of Radix Angelicae Sinensis, 0.6 part of Lac regis apis lyophilized powder.
4. the Chinese medicine of treatment sexual impotence as claimed in claim 1, it is characterized in that, be prepared from by following component, all in weight portion: 4.5 parts in Cornu Cervi Pantotrichum, 16.8 parts of Herba Epimedii, 12.0 parts of Radix Achyranthis Bidentataes, 13.0 parts of Radix Ginsengs, 26.0 parts of the Radixs Astragali, 18.0 parts of Radix Angelicae Sinensis, 0.6 part of Lac regis apis lyophilized powder.
5. the Chinese medicine of treatment sexual impotence as claimed in claim 1 is characterized in that: dosage form is capsule, tablet and granule.
6. treat the preparation method of Chinese medicine of sexual impotence according to claim 1, it is characterized in that concrete steps are as follows:
(1) get the Cornu Cervi Pantotrichum dry sterilization, be ground into fine powder by ingredients weight parts, sieve, standby;
(2) get the ginseng crude drug by ingredients weight parts and decoct with water extraction three times separately, the decocting that adds for the first time 4～7 times of amounts of Radix Ginseng weight boiled 2 hours, adding for the second time 3～6 times of water gagings of Radix Ginseng weight decocted 1.5 hours, adding 2～4 times of water gagings of Radix Ginseng weight for the third time decocted 1.0 hours, collecting decoction filters or/and leave standstill;
(3) getting Herba Epimedii, Radix Achyranthis Bidentatae, the Radix Astragali, Radix Angelicae Sinensis by ingredients weight parts decocts with water and extracts three times, the decocting that adds for the first time 4～7 times of amounts of whole extraction medical material weight boiled 2 hours, adding for the second time 3～6 times of water gagings of whole extraction medical material weight decocted 1.5 hours, adding 2～4 times of water gagings of whole extraction medical material weight for the third time decocted 1.0 hours, collecting decoction filters or/and leave standstill;
(4) get the filtrate of above-mentioned (2) and (3) or/and supernatant is condensed into thick paste, drying is ground into fine powder, sieves;
(5) add above-mentioned velvet powder, by ingredients weight parts royal jelly extracting lyophilized powder mixing, add or do not add pharmaceutic adjuvant, granulate or do not granulate, be packed into capsule and promptly get capsule; Or add pharmaceutic adjuvant an amount of granulate or do not granulate make sheet and promptly get tablet; Or add pharmaceutic adjuvant and make granule in right amount and promptly get granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100164379A CN101301347B (en) | 2008-06-02 | 2008-06-02 | Chinese medicine for treating impotence and preparation |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2008100164379A CN101301347B (en) | 2008-06-02 | 2008-06-02 | Chinese medicine for treating impotence and preparation |
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| Publication Number | Publication Date |
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| CN101301347A CN101301347A (en) | 2008-11-12 |
| CN101301347B true CN101301347B (en) | 2010-12-15 |
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| CN2008100164379A Expired - Fee Related CN101301347B (en) | 2008-06-02 | 2008-06-02 | Chinese medicine for treating impotence and preparation |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103655682A (en) * | 2013-12-21 | 2014-03-26 | 山东中大药业有限公司 | Traditional Chinese medicine for treating impotence and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1115654A (en) * | 1994-07-19 | 1996-01-31 | 于延春 | Kidney-reinforcing oral medicine and its prepn |
| CN1660404A (en) * | 2005-01-19 | 2005-08-31 | 雷小平 | Health product of preserving health, invigorating the kidney and supporting yang for male |
| CN1698878A (en) * | 2005-06-09 | 2005-11-23 | 青岛国风药业股份有限公司 | Kidney replenishing medicinal composition and its preparation process and novel use |
-
2008
- 2008-06-02 CN CN2008100164379A patent/CN101301347B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1115654A (en) * | 1994-07-19 | 1996-01-31 | 于延春 | Kidney-reinforcing oral medicine and its prepn |
| CN1660404A (en) * | 2005-01-19 | 2005-08-31 | 雷小平 | Health product of preserving health, invigorating the kidney and supporting yang for male |
| CN1698878A (en) * | 2005-06-09 | 2005-11-23 | 青岛国风药业股份有限公司 | Kidney replenishing medicinal composition and its preparation process and novel use |
Non-Patent Citations (2)
| Title |
|---|
| 张勉之.补肾活血法延缓衰老的研究.《中医药学刊》.2004,第22卷(第3期),454-457. * |
| 欧阳洪根等.中医药治疗男性免疫性不育症进展.《甘肃中医》.2005,第18卷(第2期),38-41. * |
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