CN105381260A - Traditional Chinese medicine for treating acquired immune deficiency syndrome and preparation method thereof - Google Patents
Traditional Chinese medicine for treating acquired immune deficiency syndrome and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating an acquired immune deficiency syndrome and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine is prepared from, by weight, 3-5 parts of honeysuckle, 2-4 parts of costus roots, 3-5 parts of rhizoma coptidis, 4-7 parts of radix sophorae flavescentis, 4-5 parts of herba houttuyniae, 3-5 parts of radix sophorae subprostratae, 2-3 parts of herba fibraureae recisae, 3-5 parts of radix sileris, 3-5 parts of fructus schizandrae, 2-6 parts of cornus pulp, 2-5 parts of radix angelica sinensis, 3-4 parts of panax notoginseng, 3-5 parts of glossy ganoderma, 4-5 parts of radix astragali, 2-5 parts of cynomorium songaricum, 3-6 parts of liquorice, 4-7 parts of radix ranunculi ternate, 3-6 parts of herba agrimoniae, 6-8 parts f stems of noble dendrobium, 3-5 parts of fructus chebulae, 3-5 parts of gallnuts and 5-8 parts of spreading hedyotis herbs. The traditional Chinese medicine has the effects of clearing heat and removing toxicity, benefiting Qi and promoting blood circulation, strengthening the body resistance to eliminate pathogenic factors, nourishing Yin to strengthen the essence and the like and is suitable for treating multiple clinical syndromes in the type 1 acquired immune deficiency syndrome.
Description
Technical field
The present invention relates to technical field of Chinese medicine, particularly a kind of Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS) and preparation method thereof.
Background technology
Acquired immune deficiency syndrome (AIDS), that is: acquired immune deficiency syndrome (AIDS) (or claim acquired immunity lack syndrome, English: Acquiredimmunodeficiencysyndrome, AIDS, transliteration is acquired immune deficiency syndrome (AIDS)), after a kind of retroviral infection by HIV (human immunodeficiency virus) (being called for short HIV), because immune system is damaged, become the target of attack of many waiting for an opportunity property diseases gradually, facilitate various clinical symptom, be referred to as syndrome, but not simple a kind of disease, and this syndrome is by directly contacting the oral cavity of mucous membrane tissue (mucosa), genitals, anus etc. or be with virulent blood, seminal fluid, vaginal secretion, milk and infecting.Acquired immune deficiency syndrome (AIDS) belongs to the mankind slow virus group in Retroviridae lentivirus, is divided into 1 type and 2 types.According to clinical manifestation, HIV is divided into acute stage, asymptomatic stage and AIDS stadium by China.
At present, HAART (HighlyActiveAntiretroviralTherapy, HAART) is the most basic Therapeutic Method of acquired immune deficiency syndrome (AIDS), and needs to take medicine throughout one's life.Its medicine [anti-retroviral (ARV) medicine] mainly contains: ucleosides reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease inhibitor (PIs), integrase inhibitor (raltegravir), merge enzyme inhibitor (FIs) and the large class of CCR5 inhibitor (maraviroc) six, amount to kind more than 30, domestic main employing 4 classes above, count 12 kinds, but total effect is not fairly obvious, and toxic and side effects is large after taking medicine, and produce drug resistance, treatment time is long, drug withdrawal rebounds again.
Chinese patent (number of patent application is 201210095288.6) disclosed " Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS) ", be made up of the crude drug of following portions by weight: Radix Codonopsis 9-15 part, Radix Angelicae Sinensis 4.5-9 part, Radix Rehmanniae Preparata 12-30 part, Colla Corii Asini 4.5-9 part, Rhizoma Atractylodis Macrocephalae 4.5-9 part, Poria (processed with Cinnabaris) 9-15 part, Fructus Corni (processed) meat 4.5-9 part, Radix Astragali Preparata 9-15 part, Radix Dipsaci 6-12 part processed, Fructus Crataegi (parched to brown) 6-12 part, Herba Dendrobii 6-12 part, Herba Cistanches Deserticolae (processed) 6-9 part, Herba Pogostemonis 3-9 part, Semen Coicis 9-30 part, Rhizoma Atractylodis (parched) 4.5-9 part, Lignum Aquilariae Resinatum 1.5-3 part, Herba Ajugae 9-15 part, Radix Salviae Plectranthoidis 3-4 part, Rhizoma Smilacis Chinensis 15-30 part, Caulis Akebiae 3-9 part, Herba Epimedii (processed) 3-9 part, deburring Radix et Caulis Opuntiae Dillenii 30-60 part, Herba Orostachyos 3-9 part, Concha Arcae 9-15 part, Fructus Psoraleae (parched) 4.5-9 part, Semen Trigonellae 3-9 part, the mutual compatibility of each crude drug of this invention, mend that battalion defends that deficiency, insidious blood are dry, body is thin as bavin, skinny as Artemisia, warming middle-JIAO is supporing yang, parasite killing, and dampnessization is turbid, and except anemofrigid-damp arthralgia, moisten internal organs, stomach function regulating in tune, the hematoma that disappears poison, finally reaches the object for the treatment of of AIDS.
Another Chinese patent (number of patent application is 200910272430.8) disclosed " a kind of Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS) ", arranged in pairs or groups by following 39 taste Chinese medicines and form, be specially by weight: Fructus Gardeniae 10g, Radix Scutellariae 15g, Radix Bupleuri 15g, Radix Rehmanniae 16g, Semen Plantaginis 20g, Rhizoma Alismatis 15g, Caulis Akebiae 20g, Radix Glycyrrhizae 10g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 15g, Rhizoma Et Radix Notopterygii 10g, Cortex Phellodendri 15g, Rhizoma Coptidis 10g, Rhizoma Zingiberis Recens 20g, Radix Aucklandiae 10g, Rhizoma Anemarrhenae 15g, Fructus Evodiae 10g, Radix Paeoniae Alba 10g, Fructus Alpiniae Oxyphyllae 10g, Rhizoma Atractylodis 15g, Fructus Setariae Germinatus 15g, Massa Medicata Fermentata 10g, Folium Bambusae 15g, Semen Armeniacae Amarum 15g, Gypsum Fibrosum 15g, WUFUPIAN 10g, Fructus Schisandrae Chinensis 15g, Radix Polygalae 10g, Os Draconis 15g, Fructus Hordei Germinatus 20g, Rhizoma Atractylodis Macrocephalae 20g, Ephemerantha lonchophylla (Hook. F) Hunt et Sum-merh. [Ephemerantha fimbrate (Bl.) Hunt et Summerh. 12g, Radix Isatidis 15g, Radix Astragali 15g, Calculus Bovis 10g, Cortex Dictamni 15g, Radix Gentianae 10g, Fructus Forsythiae 20g, Radix Ophiopogonis 20g.Above Chinese medicine benefiting vital QI and blood, strengthening the body resistance, raising immune function of human body, heat-clearing and toxic substances removing, copying of inhibiting HIV, plays the effect killing HIV (human immunodeficiency virus).This invention, by the combination of Chinese medicine, reaches the object for the treatment of and alleviation acquired immune deficiency syndrome (AIDS).
Also have Chinese patent (number of patent application is 201210090543.8) disclosed " a kind of Chinese medicine preparation for the treatment of acquired immune deficiency syndrome (AIDS) ", the component of this Chinese medicine preparation and the weight portion of each component are: Radix Salviae Miltiorrhizae 5-20 part, Radix Isatidis 5-20 part, Flos Lonicerae 5-20 part, Rhizoma Coptidis 5-25 part, Radix Sophorae Flavescentis 5-20 part, Radix Gentianae 5-25 part, Radix Stemonae 5-25 part, Ganoderma 5-25 part, artificial Calculus Bovis 5-15 part, artificial bear gall powder 5-20 part, Radix Bupleuri 5-20 part, Herba Selaginellae Doederleinii 5-25 part, Herba Solani Nigri 5-25 part, Herba Scutellariae Barbatae 5-25 part, Herba Lobeliae Chinensis 5-25 part.The Chinese medicine preparation of this treatment acquired immune deficiency syndrome (AIDS) is with low cost, good effect, and remission rate is high, and survival period is long.
Summary of the invention
Technical problem to be solved by this invention is to provide the effects such as one has heat-clearing and toxic substances removing, benefiting QI for activating blood circulation, strengthening vital QI to eliminate pathogenic factors, YIN nourishing consolidate, and is applicable to the Chinese medicine of the various clinical symptom in treatment 1 type acquired immune deficiency syndrome (AIDS), and provides its preparation method.
The technical solution used in the present invention is a kind of Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS) of invention, is be prepared from by the raw material of following weight portion:
Its technical scheme one optimized is prepared from by the raw material of following weight portion:
Its technical scheme two optimized is prepared from by the raw material of following weight portion:
Its technical scheme three optimized is prepared from by the raw material of following weight portion:
Meanwhile, also provide a kind of method preparing the Chinese medicine of above-mentioned treatment acquired immune deficiency syndrome (AIDS), its preparation process is as follows:
(1), raw material of Chinese medicine pretreatment:
1., above-mentioned raw material of Chinese medicine is removed foreign material, impurity, silt and the thing that goes mouldy;
2., by the Radix Sophorae Tonkinensis [Euchrestajaponica] in above-mentioned raw material of Chinese medicine, Radix Aucklandiae (Radix Vladimiriae) [AucklandialappaDecne.], Rhizoma Coptidis [CoptischinensisFranch. or CoptisdeltoideaC.Y.ChengetHsiao or CoptisteetaWall.], Caulis Fibraureae [FibraurearecisaPierre (F.tincruriaLour.)], Radix Saposhnikoviae [DivaricateSaposhnikoviaRoot], Radix Sophorae Flavescentis [Sophoraflavescens] is respectively through washing, soak, section, drying (can be dried or dry or dry, lower same) slabbing, for subsequent use,
3., washing: the Radix Astragali [stragalusmembranaceus (Fisch.) Bunge.] in above-mentioned raw material of Chinese medicine, Herba Cynomorii [CynomoriumsongaricumRupr.], Radix Glycyrrhizae [Glycyrrhizauralensis], Radix Angelicae Sinensis [Angelicasinensis.], Herba Dendrobii [DendrobiumnobileLindl] carried out respectively wash, disconnected joint section, be dried to lamellar, for subsequent use;
4., dry: the Fructus Schisandrae Chinensis [Schisandrachinensis] in above-mentioned raw material of Chinese medicine, Fructus Corni [Cornusofficinalis], Radix Ranunculi Ternati [RanunculusternatusThunb.], Fructus Chebulae [TerminaliachebulaRetz.], Radix Notoginseng [Panaxnotoginseng (Burk.) F.H.Chen], Flos Lonicerae [Lonicerajaponica] are carried out drying respectively, for subsequent use;
5., section: by Ganoderma [GanodermaLucidum (Leyss.exFr.) Karst.] section in above-mentioned raw material of Chinese medicine, drying, for subsequent use;
6. the Herba Houttuyniae [Houttuyniacordata], by above-mentioned raw material of Chinese medicine, Herba Hedyotidis Diffusae [Hedyotisdiffusa], Herba Agrimoniae [AgrimoniapilosaLedeb.] cut off respectively, dry, for subsequent use;
7., by the boiling water leaching of the fresh Galla Chinensis (RhuschinensisMill.) in above-mentioned raw material of Chinese medicine scald, when Galla Chinensis surface transfers Lycoperdon polymorphum Vitt to by yellowish-brown, pull drying out immediately, for subsequent use;
The pretreated moisture of above-mentioned raw material of Chinese medicine controls at 11-14%;
(2), pulverize: pulverize above-mentioned respectively through the former material of pretreated Chinese medicine, and cross 100-180 mesh sieve, become raw material of Chinese medicine powder, for subsequent use;
(3), mix: by the weight mixing in proportion of above-mentioned raw material of Chinese medicine powder, and stir, become mixed-powder, for subsequent use.
, sterilization and drying: above-mentioned mixed-powder is carried out dry disinfection, becomes dry disinfection medicated powder, for subsequent use;
(5), granulate: above-mentioned dry disinfection medicated powder is incapsulated or is pressed into tablet, become the Chinese medicine finished product for the treatment of acquired immune deficiency syndrome (AIDS).
Modern medicine study shows, HIV (human immunodeficiency virus) is a kind of virus attacking human immune system.It using T4 lymphocyte most important in human immune system as target of attack, engulf in a large number, destroy T4 lymphocyte, thus destroy the immune system of people, finally make immune system breaks down, human body to be fallen ill to the resistivity of various disease and dead because losing.
The acquired immune deficiency syndrome (AIDS) clinical symptoms main manifestations of acute stage is heating, pharyngalgia, night sweat, nausea,vomiting,diarrhea, erythra, arthralgia, lymphadenectasis and neurological symptom.Most of patients clinical symptoms is slight, alleviates after continuing 1-3 week.
The traditional Chinese medical science is thought: healthy energy internal memory, and heresy can not be done, heresy institute its gas that gathers must void also.From the Chinese point of view, the pathogenic factor of acquired immune deficiency syndrome (AIDS): 1. have endogenous cause of ill and exopathogenic factor, outer because diseases caused by exogenous pathogenic factor, heresy enters flesh table, and performance heating, headache, to mid-term, persistency is generated heat, inappetence, feel sick, overall pain, spleen and lymph nodes of body as a whole enlargement etc., one of its endogenous cause of ill is damp and hot, evil pestilence, and epidemic disease poison invades internal organs; Inside therefore two, be that natural endowment is not enough, in namely positive QI-insufficiency heresy can enter, secondly also have excess of sexual intercourse, blood deficiency is weak, and the evil damage of poison, feelings will is unsuccessful etc.2., when exopathogen and internal injury (positive QI-insufficiency) reciprocal causation, will form vicious cycle, HIV (human immunodeficiency virus) spreads in vivo repeatedly, and develops into aids patient to certain opportunity.3. the deficiency of kidney-QI of pathogenesis mainly patient, namely deficiency of the kidney, deficient be this, and evil pestilence, epidemic disease poison is mark, relates to the internal organs such as lung, spleen, liver, the heart simultaneously, shows deficient because of positive QI-insufficiency, and pathogen is vigorous simultaneously, causes the five internal organs all to damage and exhaustion.Based on this, the Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention, according to: the principle of " heat-clearing and toxic substances removing ", " benefiting QI for activating blood circulation ", " strengthening vital QI to eliminate pathogenic factors ", " YIN nourishing consolidates " carries out prescription, its objective is enhancing immune function of human body.
" heat-clearing and toxic substances removing " is exactly the treatment of antiviral (HIV); " strengthening vital QI to eliminate pathogenic factors " not only can improve the immunologic function of body, adjust autologous tissue's ability self rehabilitation ability in other words of human body simultaneously, namely fuselage state can be improved, the physiological function of the whole internal organs of enhancing body, finally allow body autologous tissue ability go the sterilizing that sterilizes, play the toxic and side effects reducing medicine.
Medicine composition in prescription, take heat-clearing and toxic substances removing as break-through point, based on benefiting QI for activating blood circulation, strengthening vital QI to eliminate pathogenic factors, YIN nourishing consolidates attaches most importance to.
Heat-clearing and toxic substances removing: select Flos Lonicerae, Radix Sophorae Tonkinensis, Rhizoma Coptidis, sends out speckle for the high heat of damp disease, pyretic toxicity, and has antiviral functions; Select Galla Chinensis, Caulis Fibraureae, Radix Ranunculi Ternati, for broken knot, eliminate scrofula, and have analgesia, calm effect; Select Radix Sophorae Flavescentis, Rhizoma Coptidis, Radix Sophorae Tonkinensis, Radix Saposhnikoviae, Caulis Fibraureae, fire removing toxic substances can be let out; Above Chinese medicine can not only heat-clearing and toxic substances removing, and has antiinflammatory, antiviral and enhancing immunization.
Benefiting QI for activating blood circulation: select Fructus Chebulae, Herba Agrimoniae, Radix Notoginseng, has benefiting QI for activating blood circulation, blood stasis dispelling function, significantly can improve clinical symptoms, can have certain inhibitory action again, cytotoxicity can be made to reduce, and can improve the immunologic function of body HIV (virus).
Strengthening vital QI to eliminate pathogenic factors: select Herba Hedyotidis Diffusae, the five tastes, Herba Dendrobii, Fructus Chebulae, Herba Cynomorii, Radix Glycyrrhizae, there is antivirus action, and immunity moderation function can be improved, eliminate or prevent viral infection, alleviating the infringement of virus to respiratory tract and pulmonary and spleen, promote that inflammation disappears, make impaired cell healing, improve and increase lymphocyte quantity, lymph flows into blood circulation and has recovery protein, transport fat and other nutrient substance, regulate blood plasma and interstitial fluid body balance.Lymph flowing can also be eliminated because of injured hemorrhage and enter the erythrocyte of tissue and invade the antibacterial of body, play a part very important to defend against computer virus infection, thus improve quality of life and the survival rate of HIV sufferers, make patient can reach recovery normal healthy body.
YIN nourishing consolidates: select Fructus Corni, Radix Angelicae Sinensis, Radix Notoginseng, Fructus Schisandrae Chinensis, Ganoderma, Radix Aucklandiae (Radix Vladimiriae), the Radix Astragali, for the disease of the various deficient deficiency of tonification, makes up yin-Yang insufficiency of vital energy and blood, walks dynamic unable disease.Acquired immune deficiency syndrome (AIDS) during one's sickness, general nourishing kidney-yin, lose son solid de-, deficiency of kidney-essence, Kidney-Yin virtual loss, exhaust, deficiency of both YIN and YANG, treats in order to upper Chinese medicine card by kidney essense.
Therefore, above-mentioned all medicines share, and have heat-clearing and toxic substances removing, the effect such as benefiting QI for activating blood circulation, strengthening vital QI to eliminate pathogenic factors, YIN nourishing consolidate, and make the Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention, can treat the various clinical symptom in 1 type acquired immune deficiency syndrome (AIDS).
The Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention, once selected HIV sufferers 28 example of the different state of an illness, age, sex, carried out controlled observation.
(i), clinical data
The standard all meeting " about AIDS antiretroviral therapy management work suggestion " that former Ministry of Public Health and State Administration of Traditional Chinese Medicine put into effect in 2004 and " HIV/AIDS management guidelines " that former Ministry of Public Health in 2005 is issued is tested in the blood examination of this group case processization, amount to 28 examples, wherein: women 16 example, male 12 example, age 19-60 year, mean age (34.8 ± 0.18), course of disease 6-24 month; All cases is divided into two groups at random, and two groups of patients statistical procedures PS0.05 difference in age, sex, the course of disease, without work property, has comparability.
This group case mostly after the hospitalize of various places, DeGrain.
(ii), Therapeutic Method
1, matched group: to impeach flat capsule, viracept see nelfinaivr with Zidovudine capsule, lamivudine tablet, Nai Wei.Concrete method of administration, with reference to often kind of medicine, description of taking medicine.
2, treatment group:
Prescription by weight:
Above-mentioned prescription drug is made the Chinese medicinal capsule (content of dispersion of every capsule is 0.25 gram) for the treatment of acquired immune deficiency syndrome (AIDS).
Instructions of taking: oral, three times on the one, each 4-5.
Medicine time: service once for early, middle and late 30 minutes after the meal, warm water delivery service.
Taboo: eat vinegar-pepper, raw and cold food less, forbid to smoke and drink.
Treatment previous crops blood test, make a definite diagnosis the acquired immune deficiency syndrome (AIDS) symptom belonging to which stage, 15 days each courses for the treatment of, each course for the treatment of terminates rear blood test, sees if there is curative effect or recovery from illness, adds up after three courses for the treatment of.
(iii), efficacy determination
Issue in " HIV/AIDS management guidelines " according to former Ministry of Public Health and judge that the criterion of therapeutical effect for the treatment of acquired immune deficiency syndrome (AIDS) is formulated:
1. effective: all diseases disappear, and serum inspectionization does not exist HIV-positive.
2. effective: do not occur lastingly hot in nature, headache, general weakness and overall pain, spleen and lymph nodes of body as a whole enlargement, skin purple class, lean body mass, even tremble, the phenomenon such as dull-witted.
3. invalid: after three courses for the treatment of of taking medicine, all diseases are without change, also without significant change.
Effective percentage was effectively added up with effective adding.
4, result
Table 1 is below two groups of Clinical efficacy comparison tables:
Table 1: Clinical efficacy comparison table
Shown by upper table statistical data, the Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention, the acquired immune deficiency syndrome (AIDS) for various symptom has good curative effect, and its effective percentage reaches 100%; Than matched group, effective percentage improves 66.7 percentage points.
Table 2 is below cardinal symptom and signs change contrast table (treat and observe in 30 days) before and after two groups of treatments:
Table 2 cardinal symptom and sign change contrast table
Shown by upper table statistical data, in treatment in 30 days, only have 2 example heatings in treatment group, matched group has 6 example heatings; Only have 1 example headache in treatment group, matched group has 5 example headaches; Only have 3 routine lymph gland heatings in treatment group, matched group has 8 routine lymph gland heatings; Only have 2 examples to become thin (dementia) in treatment group, matched group has 8 examples to become thin (dementia).As can be seen here, each disease improvement rate for the treatment of group all higher than matched group, and has statistical significance.
5, model case
(1), Lee, man, 27 years old, businessman, in March, 2000, fruit business is done at county town, Luxi, Yunnan, get to know beautiful Bai nationality Miss little beautiful, age only has 19 years old, cohabiting, little Li Changfa hyperpyrexia after three months, dyspnea, cough expectorant band black, sometimes blood is with, can't have dinner everyday, sometimes general weakness is felt, little beautiful father and mother words: " little beautiful be not that what is suffered from is sick, doll is had " in possible belly, Xiao Li and little beautiful one prepares to Hunan to marry, chemical examination is checked to city-level the People's Hospital, two people have infected acquired immune deficiency syndrome (AIDS), belong to initial stage, blood examination chemical examination belongs to positive, take the Chinese medicine 2 months for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention, check to city-level the People's Hospital and belong to negative, various disease disappears completely, all productive labors can be participated in live, physical recovery is fast, after given birth to a girl in May, 2002, check chemical examination all without heritability.
(2), little gorgeous, female, 20 years old, song and dance person, calendar year 2001 has suffered from a bad cold, after soon evening on daytime all as ill, gas god is depressed, green around the gills, very tired weak, singing sound of speaking is low little, aversion to wind is liked to perspire, easy catching a cold, particularly sleep evening and be often in a cold sweat, cough but no phlegm, dry mouth, seek medical advice invalid, chemical examination is checked in the People's Hospital at county level, checklist is indicated: number of white blood cells is less than normal, belong to positive, from seeing her face and tongue fur, insufficiency of lung-QI is belonged in conjunction with chemical examination argument and analysis, YIN-deficiency type, Therapeutic Principle: strengthening vital QI to eliminate pathogenic factors, QI invigorating consolidates, replenishing YIN and removing heat, damp eliminating is reduced phlegm removing toxic substances, take the Chinese medicine 3 months for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention, all transference cures, at examination in hospital, number of white blood cells reaches normal, belong to negative.Within 2003, marry, now given birth to two boys, each all carries out checking and does not all infect, without heritability.
, little jade, female, 20 years old, song and dance person, time ill the acid often of waist, shank swell and ache, brain dusk, rumbling in ear, hands, foot arch generate heat, lassitude and weak, when evening, sleep was waken up, xerostomia tongue is bitter, does not want to contact with male, has played a lot of pin, eaten a lot of medicine, and lymph node appearring in joint portion, is acquired immune deficiency syndrome (AIDS) because suspecting when examination in hospital, took the how flat capsule of Wella, zidovudine tablet, and felt under the weather after clothes, have nausea and vomiting phenomenon, took two months medicines, symptom is not felt any better, drug withdrawal.Check checklist according to patient from addressing, be diagnosed as acquired immune deficiency syndrome (AIDS), belong to " insufficiency of kidney-YANG, pathogenic heat is laid equal stress on class; Therapeutic Principle: " righting dispel evanescence of heat evil the kidney invigorating ", takes the Chinese medicine first quarter moon for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention, and vomiting phenomenon disappears, and waist, shank are not felt to ache, there is lymph node in joint portion, disappear a part, serve on 3 months, all are as normal person, go to county people's hospital to check, all are all normal.Within 2006, marry, raw a man and a woman.
, Xiao Fang, female, 21 years old, dancing hall supervisor, ill existing more than a year, waist and lower limb are unable on foot, dizzy, ring, sometimes do not hear, brain bradykinesia in ear, memory disappears, and easily forgets things, the many insomnias of dream of sleeping evening, and mouth, tongue sensation is bitter, tasteless, Multiple Hospitalization have an injection take medicine invalid.T lymphopenia is found out from laboratory test report, she subjects psychological pressure herself, oneself know and infected acquired immune deficiency syndrome (AIDS) oneself have the thought of wanting to die, persuaded through good friend afterwards, take the Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention after two months, Morbidity control, have kind of a comfort sense, substantially recovers healthy, go to the People's Hospital at county level to check, every laboratory indexes belongs to normal person.Do not recur to reach, she serve on again the Chinese medicine two months for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention, has now visited and has not recurred for 1 year 08 months, looked for a partner in marriage, and marries and has given birth to a boy.
, week certain, man, 38 years old, when being in badly off, sold blood, infected acquired immune deficiency syndrome (AIDS) by blood sales.Start April calendar year 2001 to take Abacavir, Lamivudine pharmaceutical treatment.In March, 2002, the right hip arthralgia, two weakness of the lower extremities on foot, to the People's Hospital X sheet perspective at county level, find right hip femur head necrosis, particularly overcast and rainy pain of walking is severe, companion's stomachache is had loose bowels 4 months, every day defecates 6-7 time, emaciated physique, light red tongue, white and thin fur, tense pulse, demonstration differentiate belong to the deficiency of vital energy tremble with fear warm numbness resistance card, take the Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention after 15 days, arthralgia slightly subtracts, abdomen is not bitterly, only have loose bowels, stool every day 2 times, can work, following the service after two months, the right hip joint of patient is not bitterly, all symptoms disappear substantially, can take part in the work.
, Lee, man, 48 years old, HIV antibody was positive, takes the antiviral drugs such as emtricitabine, nevirapine, prednisone, ritonavir 7 months.After taking antiviral drugs, Nausea and vomiting when namely having, and accompany upper abdomen painful abdominal mass swollen, loss of appetite.Light red tongue, yellow and greasy fur, deep and stringy pulse, sooner or later wake up, mouth is dry especially, bitter again, and the breast side of body is often full vexed, and feel unable, diagnosis belongs to damp and hot middle resistance, and taste abnormal ascending-descending of QI has gallbladder-heat concurrently.Control with dampness heat clearing away, sending down the abnormal ascending QI disappears painful abdominal mass, and clearing gallbladder heat of holding concurrently, took the Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention after 20 days, Nausea and vomiting phenomenon is eliminated, the micro-hardship of mouth, and appetite is for there being increasing, but abdominal part still slightly feeling of fullness, tongue fur is in vain micro-, and following the service is after 2 months, and all transference cures, go to a distant place to repair railway and earned money.
(7), pay certain, man, 54 years old, positive through chemical examination HIV antibody in the People's Hospital's at county level, it is 210/ul that on April 16th, 2010 looks into CD4+T lymphocyte in city-level Disease Control and Prevention Center.Started to take antiviral drugs lamivudine on April 18, stavudine, Yi Feiwei buttocks carry out treatment ten days, or Nausea and vomiting, tired, extremity all feel unable, when wakeing up evening, bitter taste is dry, and nightwear is moistening, total sleepy feel in a day, vexed.Red tongue, tongue is thick in vain, deep and stringy pulse, and mouth feed just occurs that Nausea and vomiting, big belly, appetite reduce, loose stool every day 3-5 time.Diagnosis: vomiting, the warm middle resistance of genus of feeling sick, spleen bone abnormal ascending-descending of QI.Therapeutic Method, must with dampness heat clearing away, and the sending down the abnormal ascending QI painful abdominal mass that disappears is break-through point, and take the Chinese medicine 18 days for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention, nausea and vomiting disappears, appetite increases, and stool recovers normal, every day 1 time, does things and feels there is strength, continue 3 courses for the treatment of, and heal, visit, no recurrence in 2 years.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.Explanation is below the mode exemplified, and is the form with powder, but protection scope of the present invention is not limited thereto.
Embodiment one
The phthisical Chinese medicine for the treatment of of the present embodiment, its preparation process is as follows:
(1), get the raw materials ready: get raw material of Chinese medicine Flos Lonicerae, Radix Aucklandiae (Radix Vladimiriae), Rhizoma Coptidis, Radix Sophorae Flavescentis, Herba Houttuyniae, Radix Sophorae Tonkinensis, Caulis Fibraureae, Radix Saposhnikoviae, Fructus Schisandrae Chinensis, Fructus Corni, Radix Angelicae Sinensis, Radix Notoginseng, Ganoderma, the Radix Astragali, Herba Cynomorii, Radix Glycyrrhizae, Radix Ranunculi Ternati, Herba Agrimoniae, Herba Dendrobii, Fructus Chebulae, Galla Chinensis, Herba Hedyotidis Diffusae respectively, for subsequent use;
(2), raw material of Chinese medicine pretreatment:
1., above-mentioned raw material of Chinese medicine is removed foreign material, impurity, silt and the thing that goes mouldy;
2. the Radix Sophorae Tonkinensis, by above-mentioned raw material of Chinese medicine, Radix Aucklandiae (Radix Vladimiriae), Rhizoma Coptidis, Caulis Fibraureae, Radix Saposhnikoviae, Radix Sophorae Flavescentis are respectively through washing, soaking, cut into slices, dry slabbing, for subsequent use;
3. the Radix Astragali, by above-mentioned raw material of Chinese medicine, Herba Cynomorii, Radix Glycyrrhizae, Radix Angelicae Sinensis, Herba Dendrobii carry out washing respectively, disconnected joint section, dry slabbing, for subsequent use;
4. the Fructus Schisandrae Chinensis, by above-mentioned raw material of Chinese medicine, Fructus Corni, Radix Ranunculi Ternati, Fructus Chebulae, Radix Notoginseng, Flos Lonicerae carry out drying respectively, for subsequent use;
5. the Ganoderma section, by above-mentioned raw material of Chinese medicine, drying, for subsequent use;
6. the Herba Houttuyniae, by above-mentioned raw material of Chinese medicine, Herba Hedyotidis Diffusae, Herba Agrimoniae cut off respectively, dry, for subsequent use;
7., by the fresh Galla Chinensis boiling water leaching in above-mentioned raw material of Chinese medicine scald, when Galla Chinensis surface transfers Lycoperdon polymorphum Vitt to by yellowish-brown, pull drying out immediately, for subsequent use;
The pretreated moisture of above-mentioned raw material of Chinese medicine controls at 11-14%;
(2), pulverize: pulverize above-mentioned respectively through the former material of pretreated Chinese medicine, and cross 150 mesh sieves, become raw material of Chinese medicine powder, for subsequent use;
(3), mix: the weight portion of above-mentioned raw material of Chinese medicine powder according to Flos Lonicerae 3, Radix Aucklandiae (Radix Vladimiriae) 4, Rhizoma Coptidis 5, Radix Sophorae Flavescentis 4, Herba Houttuyniae 5, Radix Sophorae Tonkinensis 5, Caulis Fibraureae 2, Radix Saposhnikoviae 3, Fructus Schisandrae Chinensis 5, Fructus Corni 6, Radix Angelicae Sinensis 2, Radix Notoginseng 3, Ganoderma 5, the Radix Astragali 4, Herba Cynomorii 2, Radix Glycyrrhizae 6, Radix Ranunculi Ternati 4, Herba Agrimoniae 6, Herba Dendrobii 6, Fructus Chebulae 5, Galla Chinensis 3, Herba Hedyotidis Diffusae 8 is mixed, and stir, become mixed-powder, for subsequent use.
, sterilization and drying: above-mentioned mixed-powder is carried out dry disinfection, becomes dry disinfection medicated powder, for subsequent use;
(5), granulate: above-mentioned dry disinfection medicated powder is incapsulated or is pressed into tablet, become the Chinese medicine finished product for the treatment of acquired immune deficiency syndrome (AIDS).
The present embodiment is applicable to the acquired immune deficiency syndrome (AIDS) for the treatment of 1 type acute stage.
Embodiment two
(3), mix: the weight portion of above-mentioned raw material of Chinese medicine powder according to Flos Lonicerae 5, Radix Aucklandiae (Radix Vladimiriae) 2, Rhizoma Coptidis 3, Radix Sophorae Flavescentis 7, Herba Houttuyniae 4, Radix Sophorae Tonkinensis 3, Caulis Fibraureae 3, Radix Saposhnikoviae 5, Fructus Schisandrae Chinensis 3, Fructus Corni 2, Radix Angelicae Sinensis 5, Radix Notoginseng 4, Ganoderma 3, the Radix Astragali 5, Herba Cynomorii 5, Radix Glycyrrhizae 3, Radix Ranunculi Ternati 7, Herba Agrimoniae 3, Herba Dendrobii 8, Fructus Chebulae 3, Galla Chinensis 4, Herba Hedyotidis Diffusae 5 is mixed, and stir, become mixed-powder, for subsequent use.
Other is identical with embodiment one.
The present embodiment is applicable to the acquired immune deficiency syndrome (AIDS) for the treatment of 1 type asymptomatic stage.
Embodiment three
(3), mix: the weight portion of above-mentioned raw material of Chinese medicine powder according to Flos Lonicerae 4, Radix Aucklandiae (Radix Vladimiriae) 3, Rhizoma Coptidis 4, Radix Sophorae Flavescentis 6, Herba Houttuyniae 5, Radix Sophorae Tonkinensis 4, Caulis Fibraureae 3, Radix Saposhnikoviae 4, Fructus Schisandrae Chinensis 4, Fructus Corni 5, Radix Angelicae Sinensis 4, Radix Notoginseng 3, Ganoderma 4, the Radix Astragali 4, Herba Cynomorii 4, Radix Glycyrrhizae 5, Radix Ranunculi Ternati 6, Herba Agrimoniae 5, Herba Dendrobii 7, Fructus Chebulae 4, Galla Chinensis 5, Herba Hedyotidis Diffusae 7 is mixed, and stir, become mixed-powder, for subsequent use.
Other is identical with embodiment one.
The present embodiment is applicable to the acquired immune deficiency syndrome (AIDS) for the treatment of 1 type AIDS stadium.
The Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS) of the present invention, is applicable to the various clinical symptom in treatment 1 type acquired immune deficiency syndrome (AIDS).
Claims (5)
1. treat a Chinese medicine for acquired immune deficiency syndrome (AIDS), it is characterized in that being prepared from by the raw material of following weight portion:
2. treat the Chinese medicine of acquired immune deficiency syndrome (AIDS) according to claim 1, it is characterized in that being prepared from by the raw material of following weight portion:
3. treat the Chinese medicine of acquired immune deficiency syndrome (AIDS) according to claim 1, it is characterized in that being prepared from by the raw material of following weight portion:
4. treat the Chinese medicine of acquired immune deficiency syndrome (AIDS) according to claim 1, it is characterized in that being prepared from by the raw material of following weight portion:
5. according to any one of claim 1-4, treat a preparation method for the Chinese medicine of acquired immune deficiency syndrome (AIDS), it is characterized in that preparation process is as follows:
(1), raw material of Chinese medicine pretreatment:
1., above-mentioned raw material of Chinese medicine is removed foreign material, impurity, silt and the thing that goes mouldy;
2. the Radix Sophorae Tonkinensis, by above-mentioned raw material of Chinese medicine, Radix Aucklandiae (Radix Vladimiriae), Rhizoma Coptidis, Caulis Fibraureae, Radix Saposhnikoviae, Radix Sophorae Flavescentis are respectively through washing, soaking, cut into slices, be dried to lamellar, for subsequent use;
3. the Radix Astragali, by above-mentioned raw material of Chinese medicine, Herba Cynomorii, Radix Glycyrrhizae, Radix Angelicae Sinensis, Herba Dendrobii carry out washing respectively, disconnected joint section, be dried to lamellar, for subsequent use;
4. the Fructus Schisandrae Chinensis, by above-mentioned raw material of Chinese medicine, Fructus Corni, Radix Ranunculi Ternati, Fructus Chebulae, Radix Notoginseng, Flos Lonicerae carry out drying respectively, for subsequent use;
5. the Ganoderma section, by above-mentioned raw material of Chinese medicine, drying, for subsequent use;
6. the Herba Houttuyniae, by above-mentioned raw material of Chinese medicine, Herba Hedyotidis Diffusae, Herba Agrimoniae cut off respectively, dry, for subsequent use;
7., by the fresh Galla Chinensis boiling water leaching in above-mentioned raw material of Chinese medicine scald, when Galla Chinensis surface transfers Lycoperdon polymorphum Vitt to by yellowish-brown, pull drying out immediately, for subsequent use;
(2), pulverize: pulverize above-mentioned respectively through the former material of pretreated Chinese medicine, and cross 100-180 mesh sieve, become raw material of Chinese medicine powder, for subsequent use;
(3), mix: by the weight mixing in proportion of above-mentioned raw material of Chinese medicine powder, and stir, become mixed-powder, for subsequent use.
, sterilization and drying: above-mentioned mixed-powder is carried out dry disinfection, becomes dry disinfection medicated powder, for subsequent use;
(5), granulate: above-mentioned dry disinfection medicated powder is incapsulated or is pressed into tablet, become the Chinese medicine finished product for the treatment of acquired immune deficiency syndrome (AIDS).
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| CN109078114A (en) * | 2017-06-13 | 2018-12-25 | 史亚军 | A kind of Chinese traditional medicine composition oral agents for treating AIDS |
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