CN104520311B - 用于降低酒精毒性的方法和组合物 - Google Patents

用于降低酒精毒性的方法和组合物 Download PDF

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Publication number
CN104520311B
CN104520311B CN201280066882.0A CN201280066882A CN104520311B CN 104520311 B CN104520311 B CN 104520311B CN 201280066882 A CN201280066882 A CN 201280066882A CN 104520311 B CN104520311 B CN 104520311B
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acetaldehyde
ethanol
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CN104520311A (zh
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保罗·塔拉雷
牛田谕介
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Johns Hopkins University
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Johns Hopkins University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/26—Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Addiction (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Enzymes And Modification Thereof (AREA)
CN201280066882.0A 2011-11-22 2012-11-21 用于降低酒精毒性的方法和组合物 Active CN104520311B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161562559P 2011-11-22 2011-11-22
US61/562,559 2011-11-22
US201161568721P 2011-12-09 2011-12-09
US61/568,721 2011-12-09
PCT/US2012/066340 WO2013078371A2 (en) 2011-11-22 2012-11-21 Methods and compositions for reducing alcohol toxicity

Publications (2)

Publication Number Publication Date
CN104520311A CN104520311A (zh) 2015-04-15
CN104520311B true CN104520311B (zh) 2018-03-13

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CN201280066882.0A Active CN104520311B (zh) 2011-11-22 2012-11-21 用于降低酒精毒性的方法和组合物

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US (2) US20150087702A1 (cg-RX-API-DMAC7.html)
EP (1) EP2782583B1 (cg-RX-API-DMAC7.html)
JP (1) JP6437823B2 (cg-RX-API-DMAC7.html)
KR (1) KR102002147B1 (cg-RX-API-DMAC7.html)
CN (1) CN104520311B (cg-RX-API-DMAC7.html)
WO (1) WO2013078371A2 (cg-RX-API-DMAC7.html)

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WO2014163512A1 (en) * 2013-04-05 2014-10-09 Manuka Health New Zealand Limited Therapeutic compositions comprising extracts of propolis and uses thereof
CN103396348B (zh) * 2013-08-21 2015-05-20 昆明龙津药业股份有限公司 蔊菜素的衍生物以及在制备抗癌药物中的应用
JP6855157B2 (ja) * 2014-10-06 2021-04-07 扶桑化学工業株式会社 水中動物用飼料、水中動物用発育向上剤、および、それらを用いた養殖魚の飼育方法
US10233146B2 (en) 2015-04-16 2019-03-19 The Research Foundation For The State University Of New York Acetylenic cyanoenones as therapeutics for inflammation and carcinogenesis
CN105251025B (zh) * 2015-11-11 2018-11-27 福州大学 Aldh2基因在制备预防苯乙烯致遗传毒性药物中的应用
JP2017195809A (ja) * 2016-04-27 2017-11-02 佐々木食品工業株式会社 アセトアルデヒドの代謝促進用食品組成物及びアセトアルデヒドの代謝促進剤
CN107789612A (zh) * 2016-08-31 2018-03-13 李镇坚 一种中药水果复合固体解酒糖及制备工艺
JP6867823B2 (ja) * 2017-02-13 2021-05-12 サッポロビール株式会社 アセトアルデヒドデヒドロゲナーゼ活性促進剤
US10849938B2 (en) 2017-09-13 2020-12-01 ZBiotics Company Gene expression system for probiotic microorganisms
CN107950726A (zh) * 2017-11-27 2018-04-24 广州六顺生物科技有限公司 一种具有解酒护肝作用的凝胶糖果、制备方法和应用
CN110101849B (zh) * 2019-04-12 2023-11-10 暨南大学 一种酶催化解酒作用的组合物及其制备方法与应用
CN110538173A (zh) * 2019-08-20 2019-12-06 郑州大学第一附属医院 异硫氰酸酯类化合物在制备食管癌靶向药中的应用
EP4041269A1 (en) * 2019-10-10 2022-08-17 Zobrius Pharma AS Improved anti-hangover composition, its preparation and uses
KR102460570B1 (ko) 2020-02-18 2022-10-28 주식회사 피코엔텍 신규한 돌연변이 효모를 함유하는 아토피 억제 조성물
CN111437280A (zh) * 2020-04-29 2020-07-24 重庆燕盈生物科技有限公司 一种基于雷公藤红素的新用途及其应用
CN118490676B (zh) * 2024-07-18 2024-09-13 暨南大学 杨芽黄素在制备延缓卵巢衰老和/或修复损伤卵巢和/或重建卵巢功能药物中的应用

Citations (3)

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KR20020014978A (ko) * 2000-08-19 2002-02-27 김기성 숙취제거 향의 조성물
WO2007016953A1 (en) * 2005-07-29 2007-02-15 Matuschka-Greiffenclau Markus Composition for reducing alcohol induced liver cancer risk
CN101977600A (zh) * 2008-01-24 2011-02-16 雷普特医疗公司 原人参二醇-型人参皂甙组合物及其用途

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US5725895B1 (en) 1995-09-15 2000-10-10 Hopkins J School Of Medicine Method of preparing food product from cruciferous seeds
US20050271754A1 (en) * 2004-06-07 2005-12-08 Cochrane Patrick W Composition for prevention or treatment of an alcohol hangover
RU2292899C2 (ru) * 2004-06-29 2007-02-10 Дмитрий Николаевич Мясников Средство и способ профилактики и уменьшения неблагоприятных проявлений острой алкогольной интоксикации (варианты) и способ получения средства
KR100661032B1 (ko) * 2005-04-19 2006-12-22 주식회사한국야쿠르트 간 기능 개선, 혈중 알코올 감소 및 항산화에 유효한조성물
JP5371428B2 (ja) * 2005-07-29 2013-12-18 ティーマ ファウンデーション アルコール代謝を和らげる、およびアルコール誘発性疾患のリスクを減少させるための組成物
US20080311276A1 (en) * 2007-06-12 2008-12-18 Kraft Foods Holdings, Inc. Production of Glucosinolates from Agricultural By-Products & Waste
CN103202838A (zh) 2013-04-16 2013-07-17 缪为民 一种具有肝脏保护作用的植物提取物组合物

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
KR20020014978A (ko) * 2000-08-19 2002-02-27 김기성 숙취제거 향의 조성물
WO2007016953A1 (en) * 2005-07-29 2007-02-15 Matuschka-Greiffenclau Markus Composition for reducing alcohol induced liver cancer risk
CN101977600A (zh) * 2008-01-24 2011-02-16 雷普特医疗公司 原人参二醇-型人参皂甙组合物及其用途

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
In vivo metabolic and antioxidative effects of sulphoraphane derived from broccoli in water- and ethanol drinking rats;Monika Okulicz et al;《Polish Journal of Food and Nutrition Sciences》;20001231;第60卷(第3期);289页摘要 *

Also Published As

Publication number Publication date
EP2782583A2 (en) 2014-10-01
KR102002147B1 (ko) 2019-07-19
KR20140106549A (ko) 2014-09-03
CN104520311A (zh) 2015-04-15
EP2782583B1 (en) 2019-09-25
JP2015509909A (ja) 2015-04-02
WO2013078371A3 (en) 2014-12-04
US20210401791A1 (en) 2021-12-30
US20150087702A1 (en) 2015-03-26
WO2013078371A2 (en) 2013-05-30
JP6437823B2 (ja) 2018-12-12
EP2782583A4 (en) 2016-04-13

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