CN104507492B - 治疗高脂血症的包含泌酸调节肽衍生物的组合物 - Google Patents

治疗高脂血症的包含泌酸调节肽衍生物的组合物 Download PDF

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Publication number
CN104507492B
CN104507492B CN201380039596.XA CN201380039596A CN104507492B CN 104507492 B CN104507492 B CN 104507492B CN 201380039596 A CN201380039596 A CN 201380039596A CN 104507492 B CN104507492 B CN 104507492B
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oxyntomodulin
fatty liver
liver disease
seq
hyperlipidemia
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CN104507492A (zh
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郑圣烨
金鎭善
张明贤
李相贤
崔仁荣
权世昌
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Hanmi Pharmaceutical Co Ltd
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Hanmi Pharmaceutical Co Ltd
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K47/6435—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a connective tissue peptide, e.g. collagen, fibronectin or gelatin
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes

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  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Immunology (AREA)
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  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
CN201380039596.XA 2012-07-25 2013-07-25 治疗高脂血症的包含泌酸调节肽衍生物的组合物 Active CN104507492B (zh)

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CN201710990018.4A CN107854691B (zh) 2012-07-25 2013-07-25 治疗高脂血症的包含泌酸调节肽衍生物的组合物

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KR10-2012-0081475 2012-07-25
KR1020120081475A KR101968344B1 (ko) 2012-07-25 2012-07-25 옥신토모듈린 유도체를 포함하는 고지혈증 치료용 조성물
PCT/KR2013/006668 WO2014017843A1 (en) 2012-07-25 2013-07-25 Composition for treating hyperlipidemia comprising oxyntomodulin derivative

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EP (3) EP3384925B1 (enExample)
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KR (1) KR101968344B1 (enExample)
CN (2) CN107854691B (enExample)
AR (1) AR091903A1 (enExample)
AU (2) AU2013293714B2 (enExample)
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Publication number Priority date Publication date Assignee Title
SG10201604564XA (en) 2011-06-10 2016-07-28 Hanmi Science Co Ltd Novel oxyntomodulin derivatives and pharmaceutical composition for treating obesity comprising the same
HRP20190265T1 (hr) 2011-06-17 2019-04-05 Hanmi Science Co., Ltd. Konjugat koji sadrži oksintomodulin i fragment imunoglobulina i njegova uporaba
KR20130049671A (ko) 2011-11-04 2013-05-14 한미사이언스 주식회사 생리활성 폴리펩타이드 결합체 제조 방법
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US9901621B2 (en) 2018-02-27
TWI708614B (zh) 2020-11-01
CA2888407A1 (en) 2014-01-30
IL236913B (en) 2020-05-31
RU2768853C1 (ru) 2022-03-25
ES2942187T3 (es) 2023-05-30
MY187988A (en) 2021-11-06
NZ731657A (en) 2020-01-31
NZ705384A (en) 2018-01-26
ZA201501238B (en) 2019-12-18
CL2020002262A1 (es) 2020-11-20
PH12015500158B1 (en) 2022-02-02
US20150182593A1 (en) 2015-07-02
CL2019001115A1 (es) 2019-06-28
UA118177C2 (uk) 2018-12-10
BR112015001596A2 (pt) 2017-08-01
AR091903A1 (es) 2015-03-11
ES2842881T3 (es) 2021-07-15
CL2017002432A1 (es) 2018-04-02
HK1206280A1 (en) 2016-01-08
SG11201500519UA (en) 2015-02-27
KR20140018462A (ko) 2014-02-13
EP2884994B1 (en) 2023-01-18
CA3121985A1 (en) 2014-01-30
TW201416087A (zh) 2014-05-01
PH12019501131A1 (en) 2020-09-14
CL2015000177A1 (es) 2015-05-04
US10493132B2 (en) 2019-12-03
CN107854691A (zh) 2018-03-30
BR122022025353B1 (pt) 2023-11-21
JP6499333B2 (ja) 2019-04-10
IL274106B1 (en) 2023-04-01
KR101968344B1 (ko) 2019-04-12
EP2884994A1 (en) 2015-06-24
ZA201905331B (en) 2020-05-27

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