CN104430348A - Sterilization composition containing kasugamycin and validamycin - Google Patents
Sterilization composition containing kasugamycin and validamycin Download PDFInfo
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- CN104430348A CN104430348A CN201410681775.XA CN201410681775A CN104430348A CN 104430348 A CN104430348 A CN 104430348A CN 201410681775 A CN201410681775 A CN 201410681775A CN 104430348 A CN104430348 A CN 104430348A
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- kasugarnycin
- jinggangmeisu
- bactericidal composition
- validamycin
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Abstract
The invention belongs to the technical field of pesticides, and particularly relates to a sterilization composition containing kasugamycin and validamycin. The weight ratio of kasugamycin to validamycin in the composition is (1:1) to (1:100). The composition plays synergistic function through compounding, and is wide in application range, low in cost, good in effect, and used for controlling diseases of banded sclerotial blight, rice blast, blight, and the like on various crops of vegetables, amphisarca, paddy rice, cotton, beans and the like.
Description
Technical field
The invention belongs to the technical field of agricultural chemicals, be specifically related to a kind of bactericidal composition containing kasugarnycin and jinggangmeisu.
Background technology
Kasugarnycin (Kasugamycin) is also known as kasugarnycin, kasumin, chemical name 5-amino-2-methyl-6-(2, 3, 4, 5, 6-carbonyl cyclohexyl oxo) pyrans-3-base amino-a-IMDA, belong to antibiotics bactericide, the esterase system of metabolism of amino acid can be disturbed, thus affect the synthesis of protein, suppress hyphal elongation and cause cell granulations, there is stronger systemic activity, its result for the treatment of is more remarkable, control vegetables, the various bacteria of the crops such as melon and fruit and the favourable agents of fungal disease, and the melon leaf look after dispenser can be made dark green and extend harvest time.
Jinggangmeisu (validacin, Valimon) is the water soluble antibiotics-glucoside compounds produced by the mutation of water streptomycete well ridge.Have 6 components, main active substances is jinggangmycin A and B.Sterling is colorless and odorless hygroscopic powder, fusing point 130-135 DEG C (decomposition), disregards under vapour pressure room temperature, and solvability is water-soluble very soon, be dissolved in methyl alcohol, dimethyl formamide, dimethyl sulfoxide (DMSO), is slightly soluble in ethanol and acetone, be insoluble in ether and ethyl acetate, stablize in neutrality and alkaline medium under room temperature, less stable in acid medium, pKb8.0.Be mainly used in rice sheath blight disease, also can be used for the control of rice green smut, corn northern and southern leaf blight and vegetables and the crop pest such as cotton, beans.
Above-mentioned two kinds of medicaments are owing to being used alone for a long time, easily cause the drug-fast generation of germ, cause drug effect obviously to decline, thus cause dosage greatly to rise, spray cycle time, and result of use is poor, add cost, the use of a large amount of agricultural chemicals, make germ resistance more serious, also affect to environment, the medicament residue of agricultural product also increases, and has influence on health and the normal existence of the mankind, animal etc.
Summary of the invention
The object of the invention is to provide a kind of for the problems referred to above and carry out composite bactericidal composition and application thereof by kasugarnycin and jinggangmeisu, said composition plays synergistic effect by composite, applied widely, cost is low, effective, can be used to prevent and treat sickle-like bacteria, root shell bacterium, rhizoctonia, pythium spp, the rotten bacterium of seedling, the fungies such as photovoltaicing leather bacteria are at grape, cucumber, tomato, potato, all kinds of vegetables, paddy rice, peanut, tobacco, medicinal material, the fusarium wilt that the various crop such as banana produce, root rot, stem rot, epidemic disease, verticillium wilt, banded sclerotial blight, the diseases such as rice blast, and strengthen low temperature, frost, arid, flood stain, poisoning, the multiple natural calamity such as fertilizer damage resist performance.There is good effect to the pesticide resistance delaying pathogen simultaneously.
In the present invention, the weight etc. of the kasugarnycin mentioned, the weight of jinggangmeisu, active ingredient, all refers to the weight after folding hundred, i.e. the weight of active principle.
Bactericidal composition containing kasugarnycin and jinggangmeisu of the present invention, its active ingredient consists of kasugarnycin and jinggangmeisu, and described kasugarnycin and the weight ratio of jinggangmeisu be, jinggangmeisu: kasugarnycin=1:1 ~ 1:100.
As preferably, described kasugarnycin and the weight ratio of jinggangmeisu be, jinggangmeisu: kasugarnycin=1:10 ~ 1:40.
Wherein, in said composition, the weight percentage of active ingredient is 1% ~ 90%.
Said composition formulation comprises wetting powder, aqua, adds auxiliary agent and excipient, and the production technology all known according to those skilled in the art can be made into required formulation.
The disease such as banded sclerotial blight, rice blast, fusarium wilt that this bactericidal composition produces in the various crop such as control vegetables, melon and fruit, paddy rice, cotton, beans.And strengthen and performance is resisted to multiple natural calamities such as low temperature, frost, arid, flooded stain, poisoning, fertilizer damages.There is good effect to the pesticide resistance delaying pathogen simultaneously.
Beneficial effect of the present invention is: undertaken composite by kasugarnycin and jinggangmeisu two kinds of bactericide, expand fungicidal spectrum, thus it is applied widely, composite composition has synergistic effect in certain proportion, not only control efficiency is good, decrease dosage and drug cost, reduce the harmful effect to environment, and greatly delay the drug-fast generation of germ.And strengthen and performance is resisted to multiple natural calamities such as low temperature, frost, arid, flooded stain, poisoning, fertilizer damages.There is good effect to the pesticide resistance delaying pathogen simultaneously.In a word, combination sterilization composition of the present invention, has obvious economic benefit and environmental benefit.
The composite mixture of kasugarnycin and jinggangmeisu different ratio is have studied to the indoor virulence of Rhizoctonia solani Kuhn with mycelial growth rate method, experimental technique adopts the abundant method of Sun Yun to calculate co-toxicity coefficient (CTC) and evaluates mixed effect, when CTC value is greater than 120, mixture has synergistic effect, are antagonisms when being less than 80, time between 80 ~ 120, there is summation action.
Concrete grammar is as follows:
Get the liquid prepared and be placed in 100ml 50-60 DEG C of PDA sterilising medium, shake up, pour in the sterilizing culture dish of diameter 60mm, after cooled and solidified, move the bacterium cake that length is consistent, diameter is 4mm of delivering a child respectively, to add the sterilising medium of equivalent coordinative solvent as blank, all operations all carries out sterile working at superclean bench, and often 3 repetitions are established in process.Put into after 27 DEG C of constant incubators cultivate 3-8 days, adopt right-angled intersection method to measure colony diameter, calculate bacteriostasis rate, EC
50, the relevant parameter such as CTC, relevant calculating formulas is as follows:
Pure amount of growth=bacterium colony average diameter-bacterium cake diameter (0.4cm)
Bacteriostasis rate=[the pure amount of growth of (contrast pure amount of growth-process pure amount of growth) × 100/ contrast] × 100%
The EC50*100 of the EC50/B agent of toxicity index TI (B)=standard agent A
The EC50*100 of the EC50/AB of actual toxicity index ATI (AB)=A
Theoretical toxicity index TTI (AB)=percentage+TI (B) the * B percentage in mixture of TI (A) * A in mixture
Co-toxicity coefficient CTC=ATI (AB)/TTI (AB) * 100
Table 1 kasugarnycin and jinggangmeisu list mixture are to the toxicity test table of rice sheath blight disease germ
From table 1, kasugarnycin and composite jinggangmycin, to rice sheath blight disease germ, there is good indoor virulence, the CTC value of seven proportionings is all more than 120, show that these two bactericide have good synergistic function under this proportioning, also can find out that mixed ratio synergy between 1:10 ~ 1:40 is particularly remarkable in the composition along with jinggangmeisu is also different from its synergistic effects different of kasugarnycin ratio simultaneously.
Embodiment
Below in conjunction with embodiment, the invention will be further described, but the present invention is not limited thereto, and the formulation preparation method in embodiment is conventional method.
Embodiment 1:11% kasugarnycin jinggangmeisu aqua, comprises following component by weight:
By whole mixing of materials, stir obtained 11% kasugarnycin jinggangmeisu aqua.
Embodiment 3:80% kasugarnycin jinggangmeisu wetting powder, comprises following component by weight:
Said components is carried out air-flow crushing, obtained 80% kasugarnycin jinggangmeisu wetting powder.
Test example: the mixture of kasugarnycin and jinggangmeisu different ratio prevents and treats the test of pesticide effectiveness of cucumber fusarium axysporum
The 3 kinds of mixtures embodiment of the present invention obtained carry out the test of pesticide effectiveness, adopt greenhouse pot culture cucumber seedling, measure single mixture of kasugarnycin and jinggangmeisu to the control efficiency of cucumber fusarium axysporum.When cucumber grows to 3 ~ 4 leaves, select the blade of growing way uniformity to adopt manual sprayer to carry out foliar spray process, inoculate pathogen after 24 hours, 7d " Invest, Then Investigate " result is cultivated in moisturizing, the results are shown in Table 2.
The control efficiency table of table 2 pair cucumber fusarium axysporum
As can be seen from Table 2, the mixture preparation of kasugarnycin and jinggangmeisu effectively can prevent and treat cucumber fusarium axysporum, and is obviously better than the control efficiency of single dose.
Claims (6)
1. containing a bactericidal composition for kasugarnycin and jinggangmeisu, it is characterized in that, its active ingredient consists of kasugarnycin and jinggangmeisu, and described kasugarnycin and the weight ratio of jinggangmeisu be, jinggangmeisu: kasugarnycin=1:1 ~ 1:100.
2. bactericidal composition according to claim 1, is characterized in that, described kasugarnycin and the weight ratio of jinggangmeisu be, jinggangmeisu: kasugarnycin=1:10 ~ 1:40.
3. bactericidal composition according to claim 1 and 2, is characterized in that, the weight percentage of described active ingredient is 1% ~ 90%.
4. bactericidal composition according to claim 1, is characterized in that, said composition formulation comprises wetting powder, aqua.
5. bactericidal composition as claimed in claim 1, is characterized in that, for preventing and treating the fungal disease on crop.
6. bactericidal composition as claimed in claim 1, is characterized in that, for preventing and treating the disease such as banded sclerotial blight, rice blast, fusarium wilt that the various crop such as vegetables, melon and fruit, paddy rice, cotton, beans produce.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410681775.XA CN104430348A (en) | 2014-11-24 | 2014-11-24 | Sterilization composition containing kasugamycin and validamycin |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410681775.XA CN104430348A (en) | 2014-11-24 | 2014-11-24 | Sterilization composition containing kasugamycin and validamycin |
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| Publication Number | Publication Date |
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| CN104430348A true CN104430348A (en) | 2015-03-25 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410681775.XA Pending CN104430348A (en) | 2014-11-24 | 2014-11-24 | Sterilization composition containing kasugamycin and validamycin |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105284337A (en) * | 2015-06-25 | 2016-02-03 | 吉林省吉阳农业科学研究院 | Organic cultivation method of northern paddy rice |
| CN108770874A (en) * | 2018-07-04 | 2018-11-09 | 来安县薜必英家庭农场 | A kind of pesticide of long-acting prevention rice blast |
-
2014
- 2014-11-24 CN CN201410681775.XA patent/CN104430348A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105284337A (en) * | 2015-06-25 | 2016-02-03 | 吉林省吉阳农业科学研究院 | Organic cultivation method of northern paddy rice |
| CN108770874A (en) * | 2018-07-04 | 2018-11-09 | 来安县薜必英家庭农场 | A kind of pesticide of long-acting prevention rice blast |
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Application publication date: 20150325 |
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| WD01 | Invention patent application deemed withdrawn after publication |