CN102696647A - Sterilizing composite containing pyraclostrobin and pyrimethanil and application - Google Patents
Sterilizing composite containing pyraclostrobin and pyrimethanil and application Download PDFInfo
- Publication number
- CN102696647A CN102696647A CN2012102188834A CN201210218883A CN102696647A CN 102696647 A CN102696647 A CN 102696647A CN 2012102188834 A CN2012102188834 A CN 2012102188834A CN 201210218883 A CN201210218883 A CN 201210218883A CN 102696647 A CN102696647 A CN 102696647A
- Authority
- CN
- China
- Prior art keywords
- pyraclostrobin
- mould amine
- phonetic mould
- pyrimethanil
- bactericidal composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention relates to a sterilizing composite in the field of pesticide compounding. The effective components of the sterilizing composite are pyraclostrobin and pyrimethanil. The weight percentage of the pyraclostrobin to the pyrimethanil is 50:1-1:50, and preferably is 5:1-1:10, and the other components are auxiliary components which allow to be used and can be accepted in pesticide. The sterilizing composite can be prepared into wettable powder, suspending agents, water agents and water dispersible granules by using the method known in the field. The sterilizing composite is used for controlling fungal disease of crops.
Description
Technical field
The invention belongs to the compounded technology field of agricultural chemicals, be specifically related to a kind ofly contain pyraclostrobin and phonetic mould amine carries out composite bactericidal composition, and the application aspect control farm crop fungus disease.
Background technology
Pyraclostrobin (Pyraclostrobin) is claimed pyraclostrobin again, chemical name N-[2-[[1-(4-chlorphenyl) pyrazole-3-yl] oxygen methyl] phenyl]-N-methoxyl group methyl carbamate; Belong to the methoxy acrylic bactericide that has the pyrazoles structure concurrently; Be the mitochondrial respiratory inhibitor, the electronics transmission suppresses mitochondrial breathing between thin race pigment b and C1 through stoping, and the interference cell energy is supplied with; Make cell death, thus the performance bactericidal action.Pyraclostrobin has excellent protection, treatment, interior suction conduction and resistance of rainwater washing against performance, and the sterilization wide spectrum, and nearly all Mycophyta (Ascomycetes, Basidiomycetes, Oomycete and Fungi Imperfecti) disease is all demonstrated good active; Simultaneously can be to making the positive physiological regulatory action of deposits yields.Not only toxicity is low for it, to non-target organism safety, and also friendly to user and Environmental security.
Phonetic mould amine (Pyrimethanil), chemical name N-(4,6-dimethyl pyrimidine-2-yl) aniline belongs to the anilino-pyrimidine series bactericidal agent, thereby contaminates infecting the also kill pathogens that the generation of enzyme stops germ through suppressing germ.Inhale conduction and fumigation action in phonetic mould amine has simultaneously, reach the position kill pathogens that the spray medicines such as flower, young fruit of plant can't arrive after the dispenser rapidly, drug effect is more stable sooner.Be used to prevent and treat cucumber, tomato, grape, strawberry, pea, leek, etc. crop gray mold, fusarium wilt and black spot of fruit tree, spot defoliation etc.
Above-mentioned two kinds of medicaments, long-term use separately causes drug-fast generation of germ and development easily, causes dosage to strengthen, and preventive effect reduces, and the lasting period shortens, and is unfavorable for environment sustainable development.The inventor proves through series of studies, pyraclostrobin and the composite use in the certain proportion scope of phonetic mould amine, and synergistic effect is comparatively obvious, can effectively improve preventive effect, reduces the medicament usage amount, thereby accomplishes the present invention.Composite research about pyraclostrobin and phonetic mould amine does not at home and abroad appear in the newspapers at present as yet.
Summary of the invention
The object of the present invention is to provide and a kind ofly carry out composite bactericidal composition and application thereof by pyraclostrobin and phonetic mould amine; Said composition plays synergistic effect through composite; Reduce drug cost, improve actual preventive effect; Can be used to prevent and treat the fungal disease on the crop, simultaneously drug-fast generation and the development that delays pathogen had better action.
Among the present invention, the weight of the pyraclostrobin of being mentioned, the weight of phonetic mould amine, active ingredient etc. all refer to the weight of rolling over after hundred, i.e. the weight of active principle.
The bactericidal composition that contains pyraclostrobin and phonetic mould amine of the present invention, its active ingredient consist of pyraclostrobin and phonetic mould amine, and the weight ratio of described pyraclostrobin and phonetic mould amine is pyraclostrobin: phonetic mould amine=50: 1～1: 50.
As preferably, the weight ratio of described pyraclostrobin and phonetic mould amine is pyraclostrobin: phonetic mould amine=5: 1～1: 10.
Wherein, the weight percentage of active ingredient is 1%～90% in the said composition.
The said composition formulation comprises wetting powder, suspending agent, aqua, water dispersible granules, adds auxiliary agent and excipient, and the production technology of all knowing according to those skilled in the art can be made into required formulation.
This bactericidal composition is used to prevent and treat the fungal disease on the crop, is particularly useful for preventing and treating fruits and vegetables gray mold, fusarium wilt, scab, spot defoliation.
Beneficial effect of the present invention is: pyraclostrobin and two kinds of bactericide of phonetic mould amine are carried out composite, because the structure between the two differs bigger, the mechanism of action is different, and the application of complex preparation can delay generation and the development of germ to single agent resistance.The two composite composition shows synergistic effect preferably in certain ratio range simultaneously; The more single agent of the bactericidal effect of mixed composition is significantly improved; Thereby reduce the medicament usage amount, reduced peasant household's drug cost, reduced harmful effect environment.
Studied the indoor virulence of the composite mixture of pyraclostrobin and the different proportionings of phonetic mould amine with the mycelial growth rate method to botrytis cinerea; Experimental technique adopts the abundant method calculating co-toxicity coefficient of Sun Yun (CTC) to estimate and uses effect with; The CTC value has synergistic effect greater than 120 o'clock mixtures; Less than 80 o'clock be antagonism, have summation action in the time of between 80～120.
Concrete grammar is following:
Get the soup for preparing and place 100ml 50-60 ℃ of PDA sterilising medium; Shake up, pour in the sterilization culture dish of diameter 60mm, after the cooled and solidified; Moving respectively delivers a child grows unanimity, diameter is the bacterium cake of 4mm; As blank, all operations all carries out sterile working at superclean bench with the sterilising medium that adds the equivalent coordinative solvent, and 3 repetitions are established in every processing.Put into 27 ℃ of constant incubators and cultivate after 3-8 days, adopt the right-angled intersection method to measure colony diameter, calculate relevant parameters such as bacteriostasis rate, EC50, CTC, the relevant calculation formula is following:
Pure amount of growth=bacterium colony average diameter-bacterium cake diameter (0.4cm)
Bacteriostasis rate=[the pure amount of growth of (contrast pure amount of growth-handle pure amount of growth) * 100/ contrast] * 100%
The EC50*100 of the EC50/B agent of toxicity index TI (B)=standard agent A
The EC50*100 of the EC50/AB of actual toxicity index ATI (AB)=A
Theoretical toxicity index TTI (AB)=percentage+TI (B) * B the percentage in mixture of TI (A) * A in mixture
Co-toxicity coefficient CTC=ATI (AB)/TTI (AB) * 100
Table 1 pyraclostrobin and phonetic mould amine list mixture are to the toxicity test table of botrytis cinerea
Visible by table 1; Pyraclostrobin and Pyrimethanil compositional; Botrytis cinerea is had good indoor virulence, and the CTC value of nine proportionings shows that all above 120 these two bactericide have good synergistic effects under this proportioning; Can find out also simultaneously that in composition different its synergistic effects along with pyraclostrobin and phonetic mould amine ratio also are different, mixed ratio synergy between 5: 1～1: 10 is particularly remarkable.
Embodiment
Below in conjunction with embodiment the present invention is described further, but the present invention is not limited thereto, the formulation preparation method among the embodiment is conventional method.
The phonetic mould amine suspending agent of embodiment 1:12% pyraclostrobin comprises following component by weight:
With whole mixing of materials, the back that stirs joins sand mill to material and carries out sand milling, makes material reach 2～5 μ m fineness, makes the phonetic mould amine suspending agent of 12% pyraclostrobin.
Embodiment 2:25% pyraclostrobin pyrimethanil water dispersible granule comprises following component by weight:
Above-mentioned mixed by prescription is even, become wetting powder through comminution by gas stream, add the granulation of a certain amount of water extrusion again, after dry screened, obtain 25% pyraclostrobin pyrimethanil water dispersible granule.
The phonetic mould amine wetting powder of embodiment 3:51% pyraclostrobin comprises following component by weight:
Said components is carried out comminution by gas stream, make the phonetic mould amine wetting powder of 51% pyraclostrobin.
The phonetic mould amine wetting powder of embodiment 4:76.5% pyraclostrobin comprises following component by weight:
Said components is carried out comminution by gas stream, make the phonetic mould amine wetting powder of 76.5% pyraclostrobin.
Embodiment 5:30% pyraclostrobin aqueous solution of pyrimethanil comprises following component by weight:
Said components is carried out mixed dissolution, make 30% pyraclostrobin aqueous solution of pyrimethanil.
Test Example: the test of pesticide effectiveness of the mixture control gray mold of cucumber of pyraclostrobin and the different proportionings of phonetic mould amine
5 kinds of mixtures that the embodiment of the invention is obtained carry out the test of pesticide effectiveness, adopt the greenhouse pot culture cucumber seedling, measure the control efficiency of single mixture of pyraclostrobin and phonetic mould amine to gray mold of cucumber.When cucumber grows to 3～4 leaves, select the blade of growing way uniformity to adopt manual sprayer to carry out the foliar spray processing, inoculate pathogen after 24 hours, preserve moisture and cultivate 7d " Invest, Then Investigate " result, the result sees table 2.
The control efficiency table of table 2 pair gray mold of cucumber
Can find out that from table 2 mixture preparation of pyraclostrobin and phonetic mould amine can effectively be prevented and treated gray mold of cucumber, and obviously be superior to the control efficiency of single agent.
Claims (6)
1. bactericidal composition that contains pyraclostrobin and phonetic mould amine, its active ingredient consists of pyraclostrobin and phonetic mould amine, and the weight ratio of described pyraclostrobin and phonetic mould amine is pyraclostrobin: phonetic mould amine=50: 1～1: 50.
2. bactericidal composition according to claim 1 is characterized in that, the weight ratio of described pyraclostrobin and phonetic mould amine is pyraclostrobin: phonetic mould amine=5: 1～1: 10.
3. bactericidal composition according to claim 1 and 2 is characterized in that, the weight percentage of described active ingredient is 1%～90%.
4. bactericidal composition according to claim 1 is characterized in that the said composition formulation comprises wetting powder, suspending agent, aqua, water dispersible granules.
5. like the described bactericidal composition of claim 1-4, it is characterized in that said composition is used to prevent and treat the farm crop fungus disease.
6. like the described bactericidal composition of claim 1-5, it is characterized in that said composition is used to prevent and treat gray mold, fusarium wilt, scab, the spot defoliation on the fruits and vegetables.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102188834A CN102696647A (en) | 2012-06-29 | 2012-06-29 | Sterilizing composite containing pyraclostrobin and pyrimethanil and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102188834A CN102696647A (en) | 2012-06-29 | 2012-06-29 | Sterilizing composite containing pyraclostrobin and pyrimethanil and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102696647A true CN102696647A (en) | 2012-10-03 |
Family
ID=46889948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012102188834A Pending CN102696647A (en) | 2012-06-29 | 2012-06-29 | Sterilizing composite containing pyraclostrobin and pyrimethanil and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102696647A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102948422A (en) * | 2012-11-06 | 2013-03-06 | 海利尔药业集团股份有限公司 | Sterilization composition containing pyraoxystrobin and pyrimethanil |
| CN108244125A (en) * | 2018-03-12 | 2018-07-06 | 佛山市盈辉作物科学有限公司 | A kind of efficient bactericidal composite of the amine of bacterium containing figured silk fabrics and pyrimethanil |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6156760A (en) * | 1996-04-26 | 2000-12-05 | Basf Aktiengesellschaft | Fungicide mixtures |
| CN101953352A (en) * | 2009-07-20 | 2011-01-26 | 中国中化股份有限公司 | Antifungal composition containing pyraclostrobin and pyrimidine compounds |
-
2012
- 2012-06-29 CN CN2012102188834A patent/CN102696647A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6156760A (en) * | 1996-04-26 | 2000-12-05 | Basf Aktiengesellschaft | Fungicide mixtures |
| CN101953352A (en) * | 2009-07-20 | 2011-01-26 | 中国中化股份有限公司 | Antifungal composition containing pyraclostrobin and pyrimidine compounds |
Non-Patent Citations (1)
| Title |
|---|
| 朱引根，等: "几种农药对桑椹小粒性菌核病的防治效果试验", 《蚕业科学》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102948422A (en) * | 2012-11-06 | 2013-03-06 | 海利尔药业集团股份有限公司 | Sterilization composition containing pyraoxystrobin and pyrimethanil |
| CN108244125A (en) * | 2018-03-12 | 2018-07-06 | 佛山市盈辉作物科学有限公司 | A kind of efficient bactericidal composite of the amine of bacterium containing figured silk fabrics and pyrimethanil |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104521989A (en) | Compound composition containing 2-(p-fluorophenyl)-5-methanesulfonyl-1,3,4-oxadiazole and amide bactericides and preparation | |
| CN102197819B (en) | Bactericidal composition and application thereof | |
| CN102715177A (en) | Sterilization combination containing pyraclostrobin and fluazinam and application thereof | |
| CN102715158A (en) | Sterilization composition containing cyazofamid and kasugamycin and application thereof | |
| CN102715179A (en) | Sterilization composition containing cyazofamid and pyraclostrobine and application thereof | |
| CN102696624A (en) | Bactericidal composition containing difenoconazole and kresoxim-methyl | |
| CN104509539A (en) | Compounded bactericide containing metalaxyl and carbendazim and used for controlling main diseases of vegetables and grape | |
| CN103719087A (en) | Sterilizing combination containing chunleimeisu and mushroom protein polysaccharide and application thereof | |
| CN106857599A (en) | A kind of bactericidal composition containing pyraclostrobin and folpet and its application | |
| CN102696647A (en) | Sterilizing composite containing pyraclostrobin and pyrimethanil and application | |
| CN103651492A (en) | Fungicidal composition containing iprodione and triclopyricarb and application thereof | |
| CN101700015B (en) | Bactericidal composition containing cyazofamid and kasugamycin and application thereof | |
| CN109042701A (en) | A kind of rosickyite azoles and the bactericidal composition of trifloxystrobin and application thereof for preventing and treating Cucumber Target Leaf Spot | |
| CN107372505A (en) | A kind of bactericidal composition and application containing bromothalonil and S-Ethyl ethylthio sulfonate | |
| CN107372548A (en) | Composition pesticide containing captan and fluorine azoles ring bacterium amine and application thereof | |
| CN101700014B (en) | Germicide composition and application | |
| CN103651453A (en) | Bactericidal composition containing hymexazol and carbendazim and application of bactericidal composition | |
| CN104430348A (en) | Sterilization composition containing kasugamycin and validamycin | |
| CN103651409A (en) | Bactericidal composition containing hymexazol and oligochitosan and application thereof | |
| CN104488891A (en) | Powdery mildew control sterilization composition | |
| CN103621521A (en) | Fungicidal composition containing benthiavalicarb-isopropyl and dimethomorph and applications thereof | |
| CN103875690A (en) | Propineb and metalaxyl-M compound bactericidal composition | |
| CN101715776A (en) | Bactericidal composition containing bromothalonil and thiophanate-methyl, and application thereof | |
| CN103975923B (en) | A kind of agricultural bactericidal composition | |
| CN104247709B (en) | A kind of bactericidal composition of synergy and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20121003 |