CN104411815B - 用于从hPSC生成胰腺祖细胞和功能性β细胞的方法和组合物 - Google Patents

用于从hPSC生成胰腺祖细胞和功能性β细胞的方法和组合物 Download PDF

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CN104411815B
CN104411815B CN201380035022.5A CN201380035022A CN104411815B CN 104411815 B CN104411815 B CN 104411815B CN 201380035022 A CN201380035022 A CN 201380035022A CN 104411815 B CN104411815 B CN 104411815B
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CN104411815A (zh
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凯勒·G
诺斯特罗·M·C
霍尔特辛格尔·A
萨兰奇·F
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University Health Network
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CN201380035022.5A 2012-04-30 2013-04-30 用于从hPSC生成胰腺祖细胞和功能性β细胞的方法和组合物 Active CN104411815B (zh)

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PL3286300T3 (pl) 2015-04-24 2021-05-04 University Of Copenhagen Izolacja bona fide komórek progenitorowych trzustki
US11332716B2 (en) 2015-07-27 2022-05-17 The Regents Of The University Of California Methods and compositions for producing pancreatic beta cells
CN106554936B (zh) * 2015-09-30 2020-05-05 海门雨霖细胞科技有限责任公司 诱导人干细胞向肝细胞定向分化的新方法
MA45747A (fr) 2016-02-24 2019-01-02 Novo Nordisk As Génération de cellules bêta fonctionnelles à partir de progéniteurs endocrines dérivés de cellules souhes pluripotentes humaines
MA45329A (fr) 2016-04-08 2019-02-13 Univ California Production de cellules bêta matures pleinement fonctionnelles à partir de progénitrices pancréatiques humaines
JP7065517B2 (ja) * 2016-07-26 2022-05-12 国立大学法人京都大学 Ｐｔｆ１ａ陽性細胞の製造方法
EP3591040A4 (en) * 2017-03-03 2020-11-11 Kyoto University METHOD OF PRODUCTION OF PANCREATIC PROGENITOR CELLS
CN111246864A (zh) * 2017-07-21 2020-06-05 森玛治疗公司 干细胞衍生的胰腺β细胞的重聚
CA2983845C (en) 2017-10-26 2024-01-30 University Of Copenhagen Generation of glucose-responsive beta cells
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CA3108275A1 (en) 2018-08-10 2020-02-13 Vertex Pharmaceuticals Incorporated Stem cell derived islet differentiation
CA3110932A1 (en) 2018-08-30 2020-03-05 Novo Nordisk A/S Generation of functional beta cells from human pluripotent stem cell-derived endocrine progenitors
CN111875675B (zh) * 2018-09-03 2021-10-01 广东新征程生命科学有限公司 表皮干细胞向胰腺细胞分化的改进方法
WO2020080550A1 (ja) * 2018-10-15 2020-04-23 Cynity株式会社 低分子化合物による内胚葉組織又は器官由来細胞からの幹／前駆細胞の作製方法
JP7385244B2 (ja) * 2019-06-27 2023-11-22 国立大学法人 東京大学 膵前駆細胞の分離方法
WO2021051256A1 (en) * 2019-09-17 2021-03-25 Center For Excellence In Molecular Cell Science, Chinese Academy Of Sciences Pancreatic pro-endocrine progenitor cells and use thereof
EP4284398A4 (en) * 2021-02-01 2025-04-02 Cedars-Sinai Medical Center Generation of functional human ipsc-derived pancreatic islets in co-culture with isogenic ipsc-derived vascular endothelial cells
CN113234664B (zh) * 2021-05-11 2024-05-10 澳门大学 一种胰腺祖细胞的制备方法及其应用
CN114634904B (zh) * 2022-05-17 2022-09-13 天津外泌体科技有限公司 高纯度胰腺祖细胞的产生方法
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JP2015519048A (ja) 2015-07-09
HK1254968A1 (zh) 2019-08-02
ES2747967T3 (es) 2020-03-12
EP2844739A1 (en) 2015-03-11
CN104411815A (zh) 2015-03-11
PT2844739T (pt) 2019-10-01
AU2013255031B2 (en) 2018-09-06
LT2844739T (lt) 2019-10-10
IN2014DN10053A (enExample) 2015-08-14
WO2013163739A1 (en) 2013-11-07
HK1208047A1 (en) 2016-02-19
CY1122058T1 (el) 2020-11-25
AU2013255031C1 (en) 2018-12-06
CA2871795A1 (en) 2013-11-07
DK2844739T3 (da) 2019-09-30
EP2844739A4 (en) 2015-12-02
CA2871795C (en) 2023-03-14
JP2018198620A (ja) 2018-12-20
PL2844739T3 (pl) 2019-12-31
AU2013255031A1 (en) 2014-12-04
HRP20191677T1 (hr) 2019-12-13
SI2844739T1 (sl) 2019-11-29
CN108004199A (zh) 2018-05-08
CN108004199B (zh) 2022-03-18
JP6759293B2 (ja) 2020-09-23
HUE046271T2 (hu) 2020-02-28
JP6397397B2 (ja) 2018-09-26
EP3594323A1 (en) 2020-01-15
EP2844739B1 (en) 2019-06-19

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